A device for collecting exhaled gas in stages

Abstract

The present invention relates to the technical field of exhaled gas sampling, and discloses an exhaled gas phased collection device, including a host system and a power supply module; the host system includes a gas drying module, an information interaction module, a gas phased collection module, a main control module and a data processing module. The information interaction module is used to select the exhaled gas collection mode and the interaction of voice and display information. The main control module controls the gas phased collection module according to the selected exhaled gas collection mode to simultaneously collect single or multiple selected exhaled gases in the ambient gas, dead space gas, and alveolar gas in phases, detect the gas collection status, and the installation status of the disposable mouthpiece and air bag during the exhaled gas collection process, and the inflation status of the air bag at the gas collection port. The above-mentioned exhaled gas phased collection device is intended to divide the gas exhaled by the human body into different stages for collection, provide technical means for collecting the corresponding stage gas for exhaled gas detection of different diseases, and improve and promote the development of disease exhaled gas detection technology.

Description

Technical Field

[0001] The present invention relates to the technical field of exhaled gas sampling, and in particular to a device for collecting exhaled gas in stages. Background Art

[0002] With the rapid development of breath testing technology for diseases in recent years, the accuracy of disease diagnosis through breath testing has been greatly improved. In addition, with the development of breath metabolomics, breath testing for diseases has become a new disease detection method in addition to imaging and blood testing. Breath testing for diseases is popular among patients due to its advantages of being non-invasive, convenient, and fast. Imaging examinations can cause significant radiation damage to the human body. When patients need to undergo high-frequency imaging examinations in a short period of time, the risk of cancer is greatly increased. When patients undergo continuous blood sugar testing, multiple finger pricks for blood collection may cause infection or even more serious consequences. Therefore, breath testing for diseases, as a non-invasive disease detection method, has a broader application prospect.

[0003] Breath testing technology characterizes human metabolic processes by measuring and analyzing the components of exhaled breath. Exhaled breath can be divided into mixed waste gas, dead space gas, and alveolar gas based on its composition and concentration. Mixed waste gas refers to a mixture of ambient air and dead space gas, containing minimal concentrations of disease-related characteristic VOCs, with a volume of approximately 150ml. Dead space gas refers to the gas that remains in the mouth, nasal cavity, and respiratory tract during exhalation, without undergoing blood-air exchange in the lungs. The characteristic VOCs it contains are closely associated with airway inflammation, kidney disease, and oral diseases, and can reflect the biochemical metabolism of areas such as the upper respiratory tract and oral cavity. Alveolar gas refers to VOCs produced by human metabolism. After blood exchanges with blood through diffusion in the pulmonary capillaries, these VOCs are expelled from the body through the respiratory tract, mouth, and nasal cavity with exhaled air. This gaseous information contains a wealth of information about a person's health status, best reflecting their current physiological state. The breath detection instruments currently widely used in clinical practice include: red blood cell life span determination breath test instrument for detecting red blood cell life span, Helicobacter pylori (Hp) test instrument for detecting Helicobacter pylori, exhaled nitric oxide (FENO) test instrument for detecting respiratory tract inflammation, disease detection electronic nose, etc.

[0004] Research has shown that exhaled breath at different stages contains characteristic VOCs for different diseases. Using these gases to detect specific diseases at corresponding stages can improve the accuracy of disease detection. However, there is currently no device that can collect exhaled breath at specific stages. Therefore, designing a device to collect exhaled breath gases at specific stages is crucial for improving the accuracy of disease detection. Summary of the Invention

[0005] In response to the shortcomings of the existing technology, the present invention proposes a staged exhaled gas collection device, which aims to divide the exhaled gas of the human body into different stages for collection, provide technical means for collecting gas in corresponding stages for exhaled gas detection of different diseases, and improve and promote the development of disease exhaled gas detection technology.

[0006] The present invention provides an exhaled gas phased collection device, comprising a host system and a power module;

[0007] The host system includes a gas drying module, an information interaction module, a gas phased acquisition module, a main control module, a data processing module and a power supply module;

[0008] The gas drying module is used to absorb water vapor in the exhaled gas and reduce the humidity in the collected gas;

[0009] The information interaction module includes an information input module and an information output module;

[0010] The information input module includes a voice input module and a display input module;

[0011] The information output module includes a voice output module and a display output module;

[0012] According to the different components and concentrations of exhaled gas, the exhalation process is divided into three stages: mixed waste gas, dead space gas and alveolar gas.

[0013] The information input module inputs the basic information of the subject and the exhaled breath collection mode through the touch screen or voice input module;

[0014] The exhaled gas collection modes include ambient gas collection, dead space gas collection, alveolar gas collection, simultaneous classification and collection of ambient gas and dead space gas, simultaneous classification and collection of ambient gas and alveolar gas, simultaneous classification and collection of dead space gas and alveolar gas, and simultaneous classification and collection of ambient gas, dead space gas and alveolar gas;

[0015] The information output module outputs prompt information and vital capacity test results through the touch screen and audio;

[0016] The gas phased collection module is used to perform the gas collection process;

[0017] The main control module includes a gas stage identification module, a gas collection determination module and a monitoring module;

[0018] The gas phase identification module is used to identify the phase of the exhaled gas;

[0019] The gas sampling determination module is used to determine whether the subject is in the exhalation state;

[0020] The monitoring module is used to monitor the situation at the port where gas needs to be collected during exhalation;

[0021] The data processing module is used to process the calculation process during the gas collection process;

[0022] The power module includes a charging device and a battery. The charging device supplies power to the exhaled gas collection device in stages and charges the battery. When the charging device is not working, the battery supplies power to the exhaled gas collection device in stages.

[0023] The information interaction module is used to select a gas collection mode, and the main control module controls the gas phase collection module according to the selected gas collection mode to complete the collection of exhaled gas in the selected phase.

[0024] Furthermore, the gas phase identification module includes a flow meter and a gas sensor module, and the gas sensor module includes an oxygen sensor module and a carbon dioxide gas sensor module;

[0025] The gas phase identification module reads the flow meter airflow data, and the gas phase identification module reads the gas concentration values ​​measured by the oxygen sensor module and the carbon dioxide sensor module respectively. and The data processing module calculates the ratio of carbon dioxide concentration to oxygen concentration as K, and the calculation formula of K is as follows:

[0026]

[0027] Furthermore, the gas phased collection module includes: a disposable mouthpiece, a first one-way valve, a first air pump, a three-way valve, a second air pump and a four-way valve;

[0028] According to the exhaled gas collection mode selected by the information input module, the main control module controls the opening and closing sequence of the pumps and valves in the gas staged collection module to achieve staged collection of gas types matching the selected gas collection mode. The pumps and valves are connected by Teflon tubes.

[0029] Furthermore, the gas collection determination module reads the flow rate VL of the flow meter;

[0030] When the flow rate of the flow meter is lower than the threshold value KL, the system is determined to be in the non-gas collection mode, all pumps and valves are closed, and all gas collection processes of the system are stopped;

[0031] When the flow rate of the flow meter is higher than KL, it is determined that the system is in gas collection mode and the gas collection process is started.

[0032] Furthermore, the monitoring module includes a mouthpiece installation detection module, an air bag installation detection module and an air bag inflation monitoring module;

[0033] The mouthpiece installation monitoring module is used to monitor the installation status of the disposable mouthpiece, and the mouthpiece installation monitoring module includes the exhalation port;

[0034] When gas collection begins, the indicator light at the exhalation port flashes to prompt the user to install the disposable mouthpiece. After the disposable mouthpiece is correctly installed, the indicator light at the exhalation port goes out.

[0035] During the exhaled breath collection process, when the mouthpiece installation monitoring module detects that the disposable mouthpiece is not correctly installed, the indicator light at the exhaled breath port flashes, the voice output module and the display output module prompt that the mouthpiece is not correctly installed, all pump valves are closed, and the exhaled breath collection process is paused. When the disposable mouthpiece is correctly installed, the exhaled breath collection process is resumed;

[0036] The air bag installation monitoring module is used to monitor the installation status of the air bag during the gas collection process at the gas collection port determined by the exhaled gas collection mode, including the first gas collection port, the second gas collection port, and the third gas collection port;

[0037] The first gas sampling port is used to collect ambient gas, the second gas sampling port is used to collect dead space gas, and the third gas sampling port is used to collect alveolar gas;

[0038] The port to be sampled refers to the port corresponding to the gas to be sampled in the phase determined by the exhaled gas sampling mode;

[0039] When gas collection starts, the indicator light at the port where gas collection is required flashes, prompting the installation of the air bag. After the air bag is correctly installed, the indicator light at the port where gas collection is required goes out.

[0040] During the exhaled breath collection process, when the air bag installation monitoring module detects that the air bag at the port requiring air collection is not correctly installed, the indicator light at the port requiring air collection that the air bag is not correctly installed flashes, and the voice output module and the display output module prompt information that the port requiring air collection is not correctly installed. The exhaled breath collection process is paused until all the air bags at the ports requiring air collection are correctly installed, and then the exhaled breath collection process is resumed. Air bags do not need to be installed at ports not requiring air collection.

[0041] The air bag inflation monitoring module is used to monitor the output value Pi of the air pressure sensor at the air collection port during the air collection process to monitor the air bag inflation status;

[0042] The air pressure sensor includes a first air pressure sensor, a second air pressure sensor, and a third air pressure sensor;

[0043] The first air pressure sensor is located at the first exhalation port and is used to monitor the environmental gas collection status of the first air bag. The second air pressure sensor is located at the second exhalation port and is used to monitor the dead space gas collection status of the second air bag. The third air pressure sensor is located at the third exhalation port and is used to monitor the alveolar gas collection status of the third air bag.

[0044] When the air bag inflation monitoring module detects that the output value Pi of a certain air pressure sensor at the port requiring air collection is less than the air bag pressure threshold PK, the air circuit is in the air collection state, and the corresponding stage gas is continuously filled into the air bag; when the output value Pi of a certain air pressure sensor at the port requiring air collection detected by the air bag inflation monitoring module is greater than or equal to the air bag pressure threshold PK, the air circuit is in the stopped air collection state, and the gas at this stage is discharged as exhaust gas after being processed by the exhaust gas sterilization and inactivation module. When the pressure values ​​of the air pressure sensors at all ports requiring air collection are greater than or equal to the air bag pressure threshold PK, the air collection stage ends;

[0045] There is no need to detect the inflation status of the air bag at the port where no gas collection is required. All gas types that do not need to be collected are treated as waste gas and discharged after being processed by the tail gas sterilization and inactivation module.

[0046] Furthermore, the information interaction module includes an information input module and an information output module; the information input module includes a voice input module and a display input module;

[0047] The display input module uses a touch screen as a carrier. By clicking on the touch screen, the user can input personal information such as the name, age, gender, department, hospital number and bed number of the tested person and select the exhaled breath collection mode. The user can also click on the touch screen to select voice input, which switches from the display input mode to the voice input mode.

[0048] The voice input module issues voice commands to input personal information such as the name, age, gender, department, hospitalization number, bed number, etc. of the subject and the selection of the exhaled breath collection mode;

[0049] The information output module includes a voice output module and a display output module. The voice output module provides voice prompts during the gas collection process. The voice prompts include voice prompts for the type of gas to be collected, voice prompts for the installation of the disposable mouthpiece and the air bag at the gas collection port, voice prompts when the disposable mouthpiece and the air bag at the gas collection port are not correctly installed during the gas collection process, voice prompts for the completion of the collection of the type of gas to be collected, voice prompts for the end of gas collection, and voice broadcasts of vital capacity.

[0050] The voice prompt information output by the voice output module is displayed on the display output module.

[0051] Furthermore, it also includes a vital capacity detection module;

[0052] The vital capacity detection module reads the gas flow rate data output by the flow meter and calculates the vital capacity of the subject. The vital capacity VC calculation formula is as follows:

[0053]

[0054] Where r is the airway radius, t is the sampling time, and v is the detected airflow velocity. is a single vital capacity measurement value, VC is the vital capacity measurement value of this exhalation test, and n is the number of times of blowing in this exhalation collection.

[0055] Furthermore, it also includes a sterilization and inactivation module, which includes an airway sterilization and inactivation module and an exhaust sterilization and inactivation module;

[0056] The airway sterilization and inactivation module includes a plurality of ultraviolet LED lamps, which are dispersed in the airway of the exhaled gas phased collection device to sterilize and inactivate the airway after the gas collection process is completed;

[0057] The tail gas sterilization and disinfection device includes a plasma generator and sterilization and disinfection particles. The plasma generator is located at the front end of the tail gas sterilization and disinfection device. The sterilization and disinfection particles fill the tube cavity and are used to sterilize and disinfect the tail gas of the gas collection device during the gas collection process before discharging it.

[0058] Furthermore, it includes an information printing module; the information printing module prints a label sticker according to the gas sampling mode selected by the information input module, the number of printed label stickers is determined by the type of gas collected by the gas sampling mode, and the label sticker includes the name, age, gender, department, hospital number, bed number, and gas stage information of the subject recorded by the information input module;

[0059] The label sticker is attached to the surface of the air bag to record the information of the person being tested and the type of gas.

[0060] Furthermore, it also includes a mobile payment template, the mobile payment module includes a payment information display module and a payment data transmission module, the payment information display module sends a payment signal to the display output module, displays the QR code information for payment, and when the user completes the payment, the payment data transmission module sends a payment success signal to the main control module;

[0061] After the main control module receives the payment success signal, the exhaled gas phased collection device starts working.

[0062] The invention adopting the above technical solution has the following advantages:

[0063] 1. The present invention can realize the simultaneous classified collection of single-stage gas, two-stage gas, or three-stage gas according to the selected gas collection mode, covering all collection methods of exhaled gas at each stage in gas detection, which is conducive to improving the accuracy of disease exhaled gas detection.

[0064] 2. Based on the information identified by the data processing module, the main control module controls the opening and closing of the first one-way valve, the first air pump, the four-way valve, the second air pump, and the three-way valve, allowing the target gas to enter a specific air bag for collection. The sterilization and inactivation module sterilizes bacteria and viruses in the airway and exhaust of the gas collection device, ensuring the safety of the gas collection process.

[0065] 3. The present invention provides a device for collecting exhaled gas in stages. After the operator uses the button collection module to select a specific gas collection mode, the gas collection operation is gradually completed according to the voice prompt. According to the selected gas collection mode, the monitoring module detects and transmits the gas sensor, the disposable mouthpiece of the air pressure sensor at the port, and the installation status of the air bag to the data processing module. The data processing module can identify the exhaled gas stage based on the detected data, and send the calculated vital capacity of the subject to the information interaction module for display and voice broadcast. BRIEF DESCRIPTION OF THE DRAWINGS

[0066] In order to more clearly illustrate the specific embodiments of the present invention, the following briefly introduces the drawings required for use in the specific embodiments. In all the drawings, each element or part is not necessarily drawn according to the actual scale.

[0067] Figure 1 This is a diagram showing the overall structure of a system according to an embodiment of the present invention;

[0068] Figure 2 This is a system structure diagram of an embodiment of the present invention in which a spirometry module is added;

[0069] Figure 3 This is a system structure diagram showing an embodiment of the present invention in which an information printing module is added;

[0070] Figure 4 This is a system structure diagram of an embodiment of the present invention in which a sterilization and inactivation module is added;

[0071] Figure 5 This is a system structure diagram that adds a mobile payment module in an embodiment of the present invention;

[0072] Figure 6 A system structure diagram showing all functions added to the embodiment of the present invention;

[0073] Figure 7 This is a structural diagram of the main control module in the host system;

[0074] Figure 8It is a structural diagram of the information interaction module in the host system;

[0075] Figure 9 This is a structural diagram of the exhaust gas deactivation module in the host system;

[0076] Figure 10 A schematic diagram of the gas connection of a gas collection module in a staged exhaled gas collection device;

[0077] Figure 11 This is a schematic diagram of the display screen interaction interface;

[0078] Figure 12 It is a schematic diagram of the drying module structure;

[0079] Figure 13 This is a schematic diagram of the exhaust gas sterilization and inactivation module structure;

[0080] Figure 14 This is a structural diagram of the appearance of a device for collecting exhaled gas in stages;

[0081] Reference numerals:

[0082] 100. Gas phased collection module; 101. Disposable mouthpiece; 102. First one-way valve; 103. First air pump; 104. Four-way valve; 105. Second air pump; 106. Three-way valve;

[0083] 200, information interaction module; 300, information input module;

[0084] 301, voice input module; 302, display input module; 3021 touch screen;

[0085] 400, gas phase identification module; 401, flow meter; 402, gas sensor module; 4021, oxygen sensor module; 4022, carbon dioxide sensor module;

[0086] 500, gas drying module; 501, color-changing silica gel particles; 502, silica gel gasket;

[0087] 600, gas collection determination module;

[0088] 700, monitoring module; 701, mouthpiece installation monitoring module;

[0089] 7011. Exhalation port; 7012. Exhalation port indicator light;

[0090] 702, air bag installation monitoring module; 7021, first gas collection port; 7022, second gas collection port; 7023, third gas collection port; 7024, first gas collection port indicator light; 7025, second gas collection port indicator light; 7026, third gas collection port indicator light;

[0091] 703, air bag inflation monitoring module; 7031, first air pressure sensor; 7032, first air bag; 7033, second air pressure sensor; 7034, second air bag; 7035, third air pressure sensor; 7036, third air bag;

[0092] 800, main control module; 801, single chip microcomputer; 802, control circuit;

[0093] 900, data processing module;

[0094] 1000, information output module; 1001, voice output module; 1002, display output module;

[0095] 1100, power module; 1101, charging device; 1102, battery;

[0096] 1200, spirometry module; 1300, information printing module; 1301, label printer; 1302, label sticker; 1303, printer outlet;

[0097] 1400, sterilization and inactivation module; 1401, airway sterilization and inactivation module; 14011, ultraviolet LED lamp; 1402, exhaust sterilization and inactivation module;

[0098] 14021. Plasma generator; 14022. Strong oxidizing sterilization and inactivation particles; 14023. Sterilization and inactivation gasket;

[0099] 1500. Mobile payment module. DETAILED DESCRIPTION

[0100] The following embodiments of the technical solution of the present invention will be described in detail with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present invention and are therefore only examples and are not intended to limit the scope of protection of the present invention.

[0101] It should be noted that, unless otherwise specified, the technical or scientific terms used in this application should have the common meanings understood by those skilled in the art to which this invention belongs. The terms "first," "second," and so on, in the description and claims of the embodiments of the present disclosure, and in the accompanying drawings, are used to distinguish similar objects and are not necessarily used to describe a specific order or precedence. It should be understood that the terms used in this manner are interchangeable where appropriate to facilitate the implementation of the embodiments of the present disclosure described herein. In addition, the terms "including," "having," and any variations thereof, are intended to cover non-exclusive inclusions. Unless otherwise specified, the term "plurality" means two or more. In the embodiments of the present disclosure, the character " / " indicates that the preceding and following objects are in an "or" relationship. For example, A / B means: A or B. The term "and / or" describes an association relationship between objects, indicating that three relationships can exist. For example, A and / or B means: A or B, or, A and B. The term "corresponding" can refer to an association relationship or a binding relationship. A and B corresponding means that there is an association relationship or a binding relationship between A and B.

[0102] like Figures 1 to 14 As shown, a device for collecting exhaled gas in stages according to the present invention includes a host system and a power module 1100;

[0103] The host system includes a gas drying module 500, an information interaction module 200, a gas phased acquisition module 100, a main control module 800, a data processing module 900, an information output module 1000, a disposable mouthpiece 101 and an air bag.

[0104] The gas drying module 500 contains color-changing silica gel particles 501 for absorbing water vapor in the exhaled gas and reducing the humidity in the collected gas. When the color-changing silica gel particles 501 change color, the color-changing silica gel particles 501 in the gas drying module 500 are replaced.

[0105] The information input module 300 is used to input the name, age, gender, department, hospital number, bed number and other information of the person being tested and to select the gas sampling mode through voice on the touch screen.

[0106] The gas phased collection module 100 is used to perform the gas collection process;

[0107] The gas phase identification module 400 is used to identify the phase of the exhaled gas;

[0108] Gas stage identification is to divide the exhalation process into three stages: mixed waste gas, dead space gas and alveolar gas according to the different components and concentrations in the exhaled gas;

[0109] The exhaled gas collection modes include ambient gas collection, dead space gas collection, alveolar gas collection, simultaneous classification and collection of ambient gas and dead space gas, simultaneous classification and collection of ambient gas and alveolar gas, simultaneous classification and collection of dead space gas and alveolar gas, and simultaneous classification and collection of ambient gas, dead space gas and alveolar gas.

[0110] The gas sampling determination module 600 is used to determine whether the subject is in the exhalation state.

[0111] The gas phase identification module 400 is used to identify mixed waste gas, dead space gas, and alveolar gas in the exhaled gas.

[0112] The main control module 800 includes a gas stage identification module 400, a gas collection determination module 600 and a monitoring module 700;

[0113] The data processing module 900 is used to process the calculation process during the gas collection process.

[0114] The power module 1100 includes a charging device 1101 and a battery 1102. The charging device 1101 supplies power to the exhaled gas collection device in stages and charges the battery 1102 at the same time. When the charging device 1101 is not working, the battery 1102 supplies power to the exhaled gas collection device in stages.

[0115] The present invention can realize the simultaneous collection of single-stage gas, two-stage gas or three-stage gas according to the selected gas collection mode, covering all collection methods of gas at each stage of exhaled gas in gas detection, which is beneficial to improving the accuracy of disease exhaled gas detection.

[0116] The gas phase identification module 400 includes a flow meter 401 and a gas sensor module 402. The gas sensor module 402 includes an oxygen sensor module 4021 and a carbon dioxide gas sensor module. The gas phase identification module 400 reads the airflow data from the flow meter 401. The first 150 ml of exhaled air from a person is mixed waste gas. The gas phase identification module 400 reads the gas concentration values ​​measured by the oxygen sensor module 4021 and the carbon dioxide sensor module 4022, respectively, as a sum. The data processing module 900 calculates the ratio of carbon dioxide concentration to oxygen concentration, K. The calculation formula for K is as follows:

[0117]

[0118] In the formula, when the volume of exhaled gas passing through the flow meter exceeds 150 ml and the calculated ratio K is greater than the threshold KN, the gas phase identification module identifies the exhaled gas phase as dead space gas. When the calculated ratio K is less than or equal to the threshold KN, the gas phase identification module identifies the exhaled gas phase as alveolar gas. The value of KN is greater than or equal to 3.5.

[0119] The information interaction module 200 includes an information input module 300 and an information output module 1000; the information input module 300 includes a voice input module 301 and a display input module 302;

[0120] The display input module 302 uses a touch screen 3021 as a carrier. The user can click on the touch screen 3021 to input personal information such as the subject's name, age, gender, department, hospitalization number, and bed number, and select the exhaled breath collection mode. The user can also click on the touch screen 3021 to select voice input, switching from the display input mode to the voice input mode. The voice input module 301 issues voice commands to input personal information such as the subject's name, age, gender, department, hospitalization number, and bed number, and select the exhaled breath collection mode.

[0121] The information output module 1000 includes a voice output module 1001 and a display output module 1002. The voice output module gives voice prompts during the gas collection process. The voice prompts include voice prompts on the type of gas to be collected, voice prompts on the installation of the disposable mouthpiece and the air bag at the port to be collected, voice prompts when the disposable mouthpiece and the air bag at the port to be collected are not correctly installed during the gas collection process, voice prompts when the collection of the type of gas to be collected is completed, voice prompts when the gas collection is finished, and voice broadcasts of vital capacity. The voice prompt information output by the voice output module is all displayed on the touch screen 3021.

[0122] The touch screen module interface consists of "Ambient Gas," "Dead Space Gas," "Alveolar Gas," "Sterilization," "End," "Select," "Voice Input," "Cancel," and "Complete." By selecting different buttons, you can collect different gases and mixed gases.

[0123] Click "Select" + "Ambient Gas" + "Finish" to complete the collection settings of ambient gas;

[0124] Click "Select" + "Dead Space Gas" + "Finish" to complete the dead space gas collection settings;

[0125] Click "Select" + "Alveolar Gas" + "Finish" to complete the alveolar gas collection settings;

[0126] Click "Select" + "Ambient Gas" + "Dead Space Gas" + "Finish" to complete the collection settings of ambient gas and dead space gas at the same time;

[0127] Click "Select" + "Ambient Gas" + "Alveolar Gas" + "Finish" to complete the collection of ambient gas and alveolar gas at the same time;

[0128] Click "Select" + "Ambient Gas" + "Dead Space Gas" + "Alveolar Gas" + "Finish" to complete the collection settings of ambient gas, dead space gas and alveolar gas at the same time.

[0129] The gas phased collection module 100 includes: a first one-way valve 102, a first air pump 103, a four-way valve 104, a second air pump 105, and a three-way valve 106; according to the exhaled gas collection mode selected by the information interaction module 200, the main control module 800 receives information from the gas phased identification module 400, the gas collection determination module 600, the monitoring module 700, and the data processing module 900. The main control module 800 controls the opening and closing sequence of the pumps and valves in the gas phased collection module 100 in an orderly manner to realize the classified collection of the gas types corresponding to the selected exhaled gas collection mode. Teflon tubes are used to connect the pumps and valves.

[0130] The gas collection determination module 600 reads the flow rate VL of the flow meter 401. When the flow rate of the flow meter 401 is lower than KL, it is determined that the system is in the non-gas collection mode, and all gas collection processes of the system are stopped; when the flow rate of the flow meter 401 is higher than KL, it is determined that the system is in the gas collection mode, and the gas collection process is started.

[0131] The monitoring module 700 includes a mouthpiece installation monitoring module 701, an air bag installation monitoring module 702, and an air bag inflation monitoring module 703;

[0132] The mouthpiece installation monitoring module 701 is used to monitor the installation status of the disposable mouthpiece 101. The mouthpiece installation monitoring module 701 includes an exhalation port 7011. When air collection begins, the indicator light at the exhalation port 7011 flashes to prompt the installation of the disposable mouthpiece 101. After the disposable mouthpiece 101 is correctly installed, the indicator light at the exhalation port 7011 goes out. During the exhalation collection process, if the mouthpiece installation monitoring module 701 detects that the disposable mouthpiece 101 is not correctly installed, the indicator light at the exhalation port 7011 flashes and the exhalation collection process is paused. When the disposable mouthpiece 101 is correctly installed, the exhalation collection process is resumed.

[0133] The air bag installation monitoring module 702 is used to monitor the installation status of the air bag during the air collection process at the air collection port determined by the exhaled air collection mode, including the first air collection port 7021, the second air collection port 7022, and the third air collection port 7023; wherein the first air collection port 7021 is used to collect ambient gas, the second air collection port 7022 is used to collect dead space gas, and the third air collection port 7023 is used to collect alveolar gas; the air collection port refers to the air collection port corresponding to the type of gas to be collected as determined by the exhaled air collection mode; when air collection starts, the indicator light at the air collection port flashes, prompting the installation of the air bag. After the air bag is correctly installed, the indicator light at the air collection port goes out; during the exhaled air collection process, when the air bag installation monitoring module 702 detects that the air bag at the air collection port is not correctly installed, the indicator light at the air collection port that is not correctly installed flashes, and the exhaled air collection process is paused until the air bags at all the air collection ports are correctly installed, and then the exhaled air collection process is resumed. Air bags do not need to be installed at ports that do not require air collection.

[0134] The air bag inflation monitoring module 703 is used to monitor the output value Pi of the air pressure sensor at the air collection port during the air collection process to monitor the air bag inflation status; the air pressure sensor includes a first air pressure sensor 7031, a second air pressure sensor 7033, and a third air pressure sensor 7035; the first air pressure sensor 7031 is located at the first exhalation port 7011, and is used to monitor the ambient air bag collection status, the second air pressure sensor 7033 is located at the second exhalation port 7011, and is used to monitor the dead space air bag collection status, and the third air pressure sensor 7035 is located at the third exhalation port 7011, and is used to monitor the alveolar air bag collection status; when the air bag inflation monitoring module 7 When the output value Pi of a certain air pressure sensor at a port requiring air collection monitored by 03 is less than the air bag pressure threshold PK, the air circuit is in the air collection state, and the corresponding stage gas is continuously filled into the air bag; when the output value Pi of a certain air pressure sensor at a port requiring air collection monitored by the air bag inflation monitoring module 703 is greater than or equal to the air bag pressure threshold PK, the air circuit is in the stopped air collection state, and the gas in this stage is discharged as exhaust gas after treatment. When the air pressure sensors at all ports requiring air collection are greater than or equal to the air bag pressure threshold PK, the air collection stage ends; there is no need to detect the air bag inflation state at ports that do not require air collection, and all gas types that do not need to be collected are treated as waste gas and discharged after treatment.

[0135] The system also includes a vital capacity detection module; the vital capacity detection module reads the gas flow rate data output by the flow meter 401 and calculates the vital capacity of the subject. The vital capacity VC calculation formula is as follows:

[0136]

[0137] Where r is the airway radius, t is the sampling time, v is the detected airflow velocity, is the single vital capacity measurement value, is the vital capacity measurement value of this exhalation test, and n is the number of puffs in this exhalation test.

[0138] The information output module 1000 includes: a voice output module 1001 and a display output module 1002; the voice output module 1001 is used for voice prompts for selecting the exhaled air collection mode, voice prompts for installing the disposable mouthpiece 101 and the air bag at the port to be collected, voice prompts when the disposable mouthpiece 101 or the air bag at the port to be collected is not correctly installed during the collection process, voice prompts when the collection of the required gas types is completed, voice prompts when the gas collection is completed, and voice broadcasts of vital capacity; the display output module 1002 displays the voice prompts of the voice output module 1001 on the touch screen.

[0139] It also includes an information printing module 1300; the information printing module 1300 prints a label sticker 1302 according to the gas sampling mode selected by the information input module 300, and the number of label stickers 1302 printed is determined by the type of gas collected by the gas sampling mode. The label sticker 1302 includes the name, age, gender, department, hospital number, bed number, and gas stage information of the person being tested; the label sticker 1302 is used to be pasted on the surface of the air bag to record the information of the testing personnel and the type of gas.

[0140] It also includes a sterilization and deactivation module 1400, which includes an airway sterilization and deactivation module 1401 and an exhaust gas sterilization and deactivation module 1402; the airway sterilization and deactivation module 1401 includes a plurality of ultraviolet LED lamps, which are dispersed in the airway of the gas collection device. After the gas collection process is completed, the airway is sterilized and deactivated; the exhaust gas sterilization and disinfection device includes a plasma generator and sterilization and disinfection particles with strong oxidizing properties. The plasma generator is located at the front end of the exhaust gas sterilization and disinfection device, and the sterilization and disinfection particles fill the tube cavity, which are used to sterilize and disinfect the exhaust gas of the gas collection device during the gas collection process and then discharge it.

[0141] A method for sampling exhaled gas in stages, using any of the above-mentioned exhaled gas sampling devices in stages, comprises the following steps:

[0142] Step S01: Selecting the exhaled breath collection mode;

[0143] Step S02: Voice prompts and indicator lights flash to remind you to install the disposable mouthpiece 101 and the air bag that needs to be installed. After the mouthpiece and the air bag at the port where gas collection is required are correctly installed, a voice prompt is given to remind you that the disposable mouthpiece 101 and the air bag that needs to be installed are correctly installed, and the indicator lights stop flashing. If the mouthpiece or the air bag at the port where gas collection is required is not correctly installed during the gas collection process, gas collection stops, and voice prompts and indicator lights flash to remind you that the port needs to be correctly installed. When all ports are correctly installed, the gas collection state is restored.

[0144] Step S03: Start the tail gas sterilization and inactivation equipment, and the gas collection device starts gas washing;

[0145] Step S04: After the gas scrubbing is completed, the gas collection determination module 600 reads the gas flow rate of the flow meter 401. When the read gas flow rate is greater than the threshold, the gas collection process is started; when the detected gas flow rate is lower than the gas flow rate, the gas collection is suspended; when the detected gas flow rate is higher than the gas flow rate, the gas collection state is resumed;

[0146] Step S05: The gas collection port only collects the gas types that need to be collected, and other gas types are treated as waste gas and then discharged through the tail gas sterilization and inactivation module 1402;

[0147] Step S06: When multiple gases are collected simultaneously, if the pressure sensor at the gas sampling port where the air bag is first filled detects that the pressure is greater than or equal to the threshold, the gas sampling port is closed and the collection of this type of gas is stopped. The remaining gas of this type in the airway is treated as waste gas and discharged after being processed by the tail gas sterilization and inactivation module 1402. The collection of other types of gases continues;

[0148] Step S07: When all the air bags of the gas types that need to be collected are full, the airway sterilization and inactivation module 1401 sterilizes and inactivates the airway for 2 minutes and then washes the airway. The information printing module 1300 automatically prints the label sticker 1302 and sticks the label sticker 1302 on the corresponding air bag. A voice prompt indicates that the exhaled breath collection process is completed and the gas collection process ends.

[0149] In some embodiments, a scrubbing process is performed.

[0150] Example 1: Ambient gas collection operation process, the operator clicks "Select" + "Ambient Gas" + "Finish" in the button module to complete the ambient gas collection setting;

[0151] Voice prompt: "Please install the air bag at the first air sampling port"

[0152] If the installed air bag is not detected at the first gas collection port, the voice prompt will continue to "Please install the air bag at the first gas collection port"; if the air bag is detected to be installed at the first gas collection port, the voice prompt will continue to "Installation completed, prepare to collect ambient gas, and start gas washing."

[0153] The first one-way valve, port A of the four-way valve, and port A of the three-way valve are opened, and the first and second air pumps begin operating. Air flows through the first and second air pumps into the inactivation device, cleaning the air path of the breath collection device. The cleaned exhaust gas is sterilized and disinfected in the inactivation device before being discharged. After the first and second air pumps have operated for 10 seconds, the first one-way valve, port A of the four-way valve, and port A of the three-way valve are closed, and the first and second air pumps stop operating. A voice prompt "Air cleaning is complete, ambient air collection is about to begin" is emitted. The first one-way valve, port A of the four-way valve, and port B of the three-way valve are opened, and the first and second air pumps begin operating. Ambient air enters the first air bag through the first and second air pumps. The first air pressure sensor collects real-time pressure at the air collection port. When the pressure detected by the first air pressure sensor reaches the threshold, the first air bag is filled with ambient air. The first one-way valve, port A of the four-way valve, and port B of the three-way valve are closed, and the first and second air pumps stop operating.

[0154] Voice prompt: "The ambient air has been collected, please proceed to the next step!"

[0155] Example 2: Dead space gas collection operation process: The operator clicks "Select" + "Dead space gas" + "Finish" in the button module to complete the dead space gas collection settings; a voice prompt "Please install the disposable mouthpiece at the exhalation port and install the air bag at the second gas collection port!"

[0156] If the disposable mouthpiece is not detected installed at the exhalation port, the voice prompt "Please install the disposable mouthpiece at the exhalation port" will continue; if the installed air bag is not detected at the second air collection port, the voice prompt "Please install the air bag at collection port 2" will continue; if the disposable mouthpiece and air bag are detected to be installed at the exhalation port and the second air collection port respectively, the voice prompt "Installation completed, prepare to collect dead space gas, start air washing". The first one-way valve, the four-way valve A port, and the three-way valve A port are opened, the first air pump and the second air pump start working, the air flow flows through the first air pump and the second air pump into the inactivation device, and the air path of the exhalation collection device is cleaned. The cleaned exhaust gas is discharged after being sterilized and disinfected by the inactivation device. After the first air pump and the second air pump have worked for 10S, the first one-way valve, the four-way valve A port, and the three-way valve A port are closed, and the first air pump and the second air pump stop working.

[0157] Voice prompt: "Gas washing is finished, dead space gas collection begins, please aim at the disposable mouthpiece and blow"

[0158] The exhaler blows into the disposable mouthpiece. When the flow rate detected by the flow meter exceeds the threshold, the first one-way valve, port A of the four-way valve, and port A of the three-way valve open, and the first and second air pumps begin operating. The flow meter measures the flow of exhaled gas, and the air flows through the first and second air pumps into the inactivation device. When the flow meter measures the exhaled gas volume reaching 150ml, four-way valve A closes, four-way valve B opens, and the second air pump stops operating. The pressure sensor at the second air sampling port detects the pressure at the second air bag, and air flows through the first air pump and the second air sampling port into the second air bag to collect dead space gas.

[0159] The sensor measurement module measures the concentrations of oxygen and carbon dioxide in exhaled gas. When the measured oxygen concentration / carbon dioxide concentration is less than or equal to 4, indicating that the exhaled gas is alveolar gas, four-way valve B is closed and three-way valve A is opened. Alveolar gas passes through four-way valve A and the second air pump, and is disinfected and sterilized by the inactivation device before being discharged. When the airflow rate detected by the flow meter falls below the threshold, indicating that exhalation has ended, the first one-way valve, port A of the four-way valve, and port A of the three-way valve are closed, and the first and second air pumps are deactivated.

[0160] The exhaler exhales again and repeats the above dead space gas collection process until the air pressure detected by the second air pressure sensor reaches the threshold, indicating that the second air bag is full of dead space gas. Close the first one-way valve, four-way valve B, and the first air pump. The voice prompt "The dead space gas has been collected and the air washing is about to begin!" The first one-way valve, the four-way valve A port, and the three-way valve A port are opened, and the first air pump and the second air pump start working. The air flow flows through the first air pump and the second air pump into the inactivation device to clean the air path of the exhalation collection device. The cleaned exhaust gas is sterilized and disinfected by the inactivation device and then discharged. After the first air pump and the second air pump have worked for 20S, the first one-way valve, the four-way valve A port, and the three-way valve A port are closed, and the first air pump and the second air pump stop working. The voice prompt "The air washing is completed, please proceed to the next operation!"

[0161] Example 3: Dead space gas collection operation process: The operator clicks "Select" + "Alveolar Gas" + "Finish" in the button module to complete the alveolar gas collection settings; a voice prompt "Please install the disposable mouthpiece at the exhalation port and install the air bag at the third gas collection port."

[0162] If the disposable mouthpiece is not detected installed at the exhalation port, the voice prompt will continue to "Please install the disposable mouthpiece at the exhalation port"; if the air bag is not detected installed at the third air collection port, the voice prompt will continue to "Please install the air bag at collection port 3"; if the disposable mouthpiece and air bag are detected to be installed at the exhalation port and the third air collection port respectively, the voice prompt will continue to "Installation completed, prepare to collect alveolar gas, start air washing".

[0163] The first one-way valve, port A of the four-way valve, and port A of the three-way valve are opened, and the first and second air pumps begin operating. Air flows through the first and second air pumps and into the inactivation device, cleaning the air path of the breath collection device. The cleaned exhaust gas is sterilized and disinfected by the inactivation device before being discharged. After the first and second air pumps have operated for 30 seconds, the first one-way valve, port A of the four-way valve, and port A of the three-way valve are closed, and the first and second air pumps cease operation.

[0164] Voice prompt: "Air washing is completed, start collecting alveolar gas, please blow into the disposable mouthpiece"

[0165] The exhaler blows into the disposable mouthpiece. When the airflow velocity detected by the flowmeter exceeds the threshold, the first one-way valve, port A of the four-way valve, and port A of the three-way valve open, and the first and second air pumps begin operating. The flowmeter measures the flow of exhaled gas, and the airflow flows through the first and second air pumps into the inactivation device. The sensor measurement module begins measuring the concentrations of oxygen and carbon dioxide in the exhaled gas. When the measured oxygen concentration / carbon dioxide concentration is less than or equal to 4, it indicates that the exhaled gas is alveolar gas. The four-way valve A and three-way valve A are closed, and the four-way valve C is opened. The second air pump stops operating, and the pressure sensor at the third air sampling port detects the pressure at the third air bag. The air flows through the first air pump and the third air sampling port into the third air bag to collect alveolar gas. When the airflow velocity detected by the flowmeter falls below the threshold, indicating that the exhalation has ended, the first one-way valve and port C of the four-way valve are closed, and the first air pump stops operating.

[0166] The exhaler exhales again, repeating the alveolar gas collection process until the pressure detected by the third pressure sensor reaches the threshold, indicating that the third air bag is full of alveolar gas. Close the first one-way valve, four-way valve C, and the first air pump. A voice prompt appears: "Alveolar gas collection is complete, and air washing will begin!"

[0167] The first one-way valve, port A of the four-way valve, and port A of the three-way valve are opened, and the first and second air pumps begin operating. Air flows through the first and second air pumps and flows into the inactivation device, cleaning the air path of the breath collection device. The cleaned exhaust gas is sterilized and disinfected by the inactivation device before being discharged. After the first and second air pumps have operated for 20 seconds, the first one-way valve, port A of the four-way valve, and port A of the three-way valve are closed, and the first and second air pumps stop operating. A voice prompt appears: "Air cleaning is complete, please proceed to the next operation!"

[0168] Example 4: Operation process for simultaneous collection of ambient gas and dead space gas. The operator clicks "Select" + "Ambient Gas" + "Dead Space Gas" + "Finish" in the button module to complete the simultaneous collection of ambient gas and dead space gas. The voice prompt "Please install the disposable mouthpiece at the exhalation port and install the air bag at the first and second air collection ports"

[0169] If the installed disposable mouthpiece is not detected at the exhalation port, the voice prompt will continue, "Please install the disposable mouthpiece at the exhalation port"; if the installed air bag is not detected at the first gas collection port, the voice prompt will continue, "Please install the air bag at the first gas collection port"; if the installed air bag is not detected at the second gas collection port, the voice prompt will continue, "Please install the air bag at the second gas collection port"; if the disposable mouthpiece is detected at the exhalation port, and the air bags are detected to be installed at the first and second gas collection ports, the voice prompt will continue, "Installation completed, prepare to collect ambient air and dead space gas, start gas washing".

[0170] The first one-way valve, the A port of the four-way valve, and the A port of the three-way valve are opened, and the first and second air pumps start working. The air flows through the first and second air pumps and flows into the inactivation device to clean the air path of the breath collection device. The cleaned tail gas is sterilized and disinfected by the inactivation device and then discharged. After the first and second air pumps have worked for 10 seconds, the first one-way valve, the A port of the four-way valve, and the A port of the three-way valve are closed, and the first and second air pumps stop working. A voice prompt is given: "The air cleaning is completed and the ambient air is about to be collected."

[0171] The first one-way valve, port A of the four-way valve, and port B of the three-way valve are opened, and the first and second air pumps begin operating. Ambient air enters the first air bag through the first and second air pumps. The first air pressure sensor collects the real-time pressure value at the air sampling port. When the pressure detected by the first air pressure sensor reaches the threshold, it indicates that the first air bag is full of ambient air. The first one-way valve, port A of the four-way valve, and port B of the three-way valve are closed; the first and second air pumps stop operating. A voice prompt is emitted: "Ambient air collection is complete. Dead space gas collection has begun. Please exhale into the disposable mouthpiece!"

[0172] The exhaler blows into the disposable mouthpiece. When the airflow rate detected by the flowmeter exceeds the threshold, the first one-way valve, the four-way valve A port, and the three-way valve A port open, and the first and second air pumps start working. The flowmeter measures the flow of exhaled gas, and the airflow flows through the first and second air pumps into the inactivation device. When the flowmeter measures that the exhaled gas reaches 150ml, the four-way valve A closes, the four-way valve B opens, the second air pump stops working, and the pressure sensor at the second air sampling port detects the pressure at the second air bag. The airflow enters the second air bag through the first and second air sampling ports, collects dead space gas, and the sensor measurement module begins to measure the concentration of oxygen and carbon dioxide in the exhaled gas. When the measured carbon dioxide concentration / oxygen concentration is equal to 4, indicating that the exhaled gas is alveolar gas, the four-way valve B is closed and the three-way valve A is opened. The alveolar gas passes through the four-way valve A and the second air pump and is discharged after disinfection and sterilization by the inactivation device.

[0173] When the air flow rate detected by the flow meter is lower than the threshold, indicating that the exhalation has ended, the first one-way valve, the four-way valve A port, and the three-way valve A port are closed, and the first air pump and the second air pump stop working.

[0174] The exhaler exhales again, repeating the dead space gas collection process until the pressure detected by the second pressure sensor reaches the threshold, indicating that the second air bag is full of dead space gas. Close the first one-way valve, four-way valve B, and the first air pump. A voice prompt appears: "Dead space gas collection is complete, and air cleaning will begin!"

[0175] The first one-way valve, port A of the four-way valve, and port A of the three-way valve are opened, and the first and second air pumps begin operating. Air flows through the first and second air pumps and flows into the inactivation device, cleaning the air path of the breath collection device. The cleaned exhaust gas is sterilized and disinfected by the inactivation device before being discharged. After the first and second air pumps have operated for 20 seconds, the first one-way valve, port A of the four-way valve, and port A of the three-way valve are closed, and the first and second air pumps stop operating. A voice prompt appears: "Air cleaning is complete, please proceed to the next operation!"

[0176] Example 5: Operation process for simultaneous collection of ambient gas and dead space gas. The operator clicks "Select" + "Ambient Gas" + "Alveolar Gas" + "Finish" in the button module to complete the simultaneous collection of ambient gas and alveolar gas. The voice prompt "Please install the disposable mouthpiece at the exhalation port and install the air bag at the first and third gas collection ports"

[0177] If the installed disposable mouthpiece is not detected at the exhalation port, the voice prompt will continue, "Please install the disposable mouthpiece at the exhalation port"; if the installed air bag is not detected at the first air collection port, the voice prompt will continue, "Please install the air bag at the first air collection port"; if the installed air bag is not detected at the third air collection port, the voice prompt will continue, "Please install the air bag at the third air collection port"; if the disposable mouthpiece is detected at the exhalation port, and the air bags are detected to be installed at the first and third air collection ports, the voice prompt will continue, "Installation completed, prepare to collect ambient air and dead space gas, start gas washing".

[0178] The first check valve, port A of the four-way valve, and port A of the three-way valve are opened, and the first and second air pumps begin operating. Air flows through the first and second air pumps into the inactivation device, cleaning the air path of the breath collection device. The cleaned exhaust gas is sterilized and disinfected in the inactivation device before being discharged. After the first and second air pumps have operated for 10 seconds, the first check valve, port A of the four-way valve, and port A of the three-way valve are closed, and the first and second air pumps stop operating. A voice prompt "Air cleaning is complete, ambient air collection is about to begin" is emitted. The first check valve, port A of the four-way valve, and port B of the three-way valve are opened, and the first and second air pumps begin operating. Ambient air enters the first air bag through the first and second air pumps. The first air pressure sensor collects real-time pressure at the air collection port. When the pressure detected by the first air pressure sensor reaches the threshold, the first air bag is filled with ambient air. The first check valve, port A of the four-way valve, and port B of the three-way valve are closed, and the first and second air pumps stop operating.

[0179] The voice prompt says, "The environmental gas collection has been completed. Alveolar gas collection has begun. Please exhale into the disposable mouthpiece!" The exhaler blows into the disposable mouthpiece. When the airflow velocity detected by the flowmeter exceeds the threshold, the first one-way valve, port A of the four-way valve, and port A of the three-way valve open, and the first and second air pumps start working. The flowmeter measures the flow of the exhaled gas, and the airflow flows through the first and second air pumps into the inactivation device.

[0180] The sensor measurement module begins measuring the oxygen and carbon dioxide concentrations in the exhaled gas. When the measured oxygen concentration / carbon dioxide concentration is less than or equal to 4, indicating that the exhaled gas is alveolar gas, four-way valve A and three-way valve A are closed, four-way valve C is opened, the second air pump stops, and the pressure sensor at the third air sampling port detects the pressure at the third air bag. Air flows through the first air pump and the third air sampling port into the third air bag, collecting alveolar gas. When the airflow rate detected by the flowmeter falls below the threshold, indicating that the exhalation has ended, the first one-way valve and four-way valve C are closed, and the first air pump stops. The exhaler exhales again, and the alveolar gas collection process repeats until the pressure detected by the third pressure sensor reaches the threshold, indicating that the third air bag is full of alveolar gas. The first one-way valve, four-way valve C, and the first air pump are closed.

[0181] Voice prompt: "Alveolar gas collection is complete, gas washing is about to begin!"

[0182] The first one-way valve, port A of the four-way valve, and port A of the three-way valve are opened, and the first and second air pumps begin to operate. Air flows through the first and second air pumps and flows into the inactivation device, cleaning the air path of the breath collection device. The cleaned exhaust gas is sterilized and disinfected by the inactivation device before being discharged. After the first and second air pumps have operated for 20 seconds, the first one-way valve, port A of the four-way valve, and port A of the three-way valve are closed, and the first and second air pumps stop operating. A voice prompt appears: "Air washing is complete. Please proceed to the next operation!"

[0183] Example 6: Operation process for simultaneous collection of ambient gas and dead space gas: the operator clicks "Select" + "Ambient Gas" + "Dead Space Gas" + "Alveolar Gas" + "Finish" in the button module to complete the simultaneous collection of ambient gas, dead space gas and alveolar gas; a voice prompt says "Please install the disposable mouthpiece at the exhalation port, and install the air bags at the first air collection port, the first air collection port, and the third air collection port."

[0184] If the installed disposable mouthpiece is not detected at the exhalation port, the voice prompt "Please install the disposable mouthpiece at the exhalation port" will continue; if the installed air bag is not detected at the first gas collection port, the voice prompt "Please install the air bag at the first gas collection port" will continue; if the installed air bag is not detected at the second gas collection port, the voice prompt "Please install the air bag at the second gas collection port" will continue; if the installed air bag is not detected at the third gas collection port, the voice prompt "Please install the air bag at the third gas collection port" will continue; if a disposable mouthpiece is detected at the exhalation port, and the air bags are detected to be installed at the first, second and third gas collection ports, the voice prompt "Installation completed, prepare for comprehensive collection, start gas washing".

[0185] The first one-way valve, port A of the four-way valve, and port A of the three-way valve are opened, and the first and second air pumps begin operating. Air flows through the first and second air pumps into the inactivation device, purging the air path of the breath collection device. The purged exhaust gas is sterilized and disinfected by the inactivation device before being discharged. After the first and second air pumps have operated for 10 seconds, the first one-way valve, port A of the four-way valve, and port A of the three-way valve are closed, and the first and second air pumps stop operating. A voice prompt "Air purging is complete, ambient air collection is about to begin" is emitted. The first one-way valve, port A of the four-way valve, and port B of the three-way valve are opened, and the first and second air pumps begin operating. Ambient air enters the first air bag through the first and second air pumps. The first air pressure sensor collects real-time pressure at the air collection port. When the pressure detected by the first air pressure sensor reaches the threshold, the first air bag is filled with ambient air. The first one-way valve, port A of the four-way valve, and port B of the three-way valve are closed, and the first and second air pumps stop operating. A voice prompt says, "The collection of ambient air has been completed. The collection of dead space air and alveolar air has begun. Please exhale into the disposable mouthpiece!" The person exhaling blows into the disposable mouthpiece. When the airflow velocity detected by the flow meter exceeds the threshold, the first one-way valve, port A of the four-way valve, and port A of the three-way valve open, and the first and second air pumps start working. The flow meter measures the flow of the exhaled gas. The airflow flows through the first and second air pumps into the inactivation device, and is then disinfected and sterilized by the inactivation device before being discharged from the exhaled air collection device.

[0186] When the flowmeter measures that the exhaled gas reaches 150ml, four-way valve A is closed, four-way valve B is opened, the second air pump stops working, and the pressure sensor at the second gas sampling port detects the pressure at the second air bag. The air flows through the first air pump and the second gas sampling port into the second air bag to collect dead space gas. The sensor measurement module starts to measure the concentrations of oxygen and carbon dioxide in the exhaled gas.

[0187] When the measured oxygen concentration / carbon dioxide concentration is equal to 4, it indicates that the exhaled gas at this time is alveolar gas. Close the four-way valve B and open the four-way valve C. The air pressure sensor at the third gas sampling port detects the pressure at the third air bag; the air flows through the first air pump and the third gas sampling port into the third air bag to collect alveolar gas.

[0188] When the air flow velocity detected by the flow meter is lower than the threshold, it indicates that the exhalation has ended, the first one-way valve and the C port of the four-way valve are closed, and the first air pump stops working.

[0189] When the exhaler collects their next breath, the above gas collection process repeats until the pressure detected by the third pressure sensor reaches the threshold, indicating that the third air bag is full of alveolar gas. Four-way valve C is closed, four-way valve A is opened, and the second air pump begins operation. Alveolar gas now flows through the first and second air pumps into the inactivation device, which disinfects and sterilizes the alveolar gas before it is discharged from the exhaled breath collection device. When the flow rate detected by the flow meter falls below the threshold, the first one-way valve and four-way valve B are closed.

[0190] When the exhaler collects the next exhaled breath and the airflow velocity detected by the flow meter exceeds the threshold, the first one-way valve, port A of the four-way valve, and port A of the three-way valve are opened, and the first air pump and the second air pump start working. The flow meter measures the flow of the exhaled gas, and the airflow flows through the first air pump and the second air pump into the inactivation device, and is then discharged from the exhaled breath collection device after being disinfected and sterilized by the inactivation device.

[0191] When the flowmeter measures that the exhaled gas reaches 150ml, four-way valve A is closed, four-way valve B is opened, the second air pump stops working, and the pressure sensor at the second gas sampling port detects the pressure at the second air bag. The air flows through the first air pump and the second gas sampling port into the second air bag to collect dead space gas. The sensor measurement module begins to measure the concentrations of oxygen and carbon dioxide in the exhaled gas. When the measured oxygen concentration / carbon dioxide concentration is equal to 4, it indicates that the exhaled gas at this time is alveolar gas. The four-way valve C is closed, the four-way valve A is opened, and the second air pump starts working. At this time, the alveolar gas enters the inactivation device through the first air pump and the second air pump. The inactivation device disinfects and sterilizes the alveolar gas and then discharges it from the exhaled gas collection device. When the flow value detected by the flowmeter is lower than the threshold, the first one-way valve and four-way valve B are closed.

[0192] When the exhaler collects the next breath, the above gas collection process is repeated until the measured value of the second pressure sensor reaches the threshold, indicating that the second air bag is full of dead space gas. Close the first one-way valve and four-way valve B. A voice prompt "Exhaled breath collection is complete, and gas washing will begin soon!"

[0193] The first one-way valve, port A of the four-way valve, and port A of the three-way valve are opened, and the first air pump and the second air pump are in operation. The air flows through the first air pump and the second air pump and flows into the inactivation device to clean the air path of the breath collection device. The cleaned exhaust gas is sterilized and disinfected by the inactivation device and then discharged. After the first and second air pumps have been working for 20 seconds, the first one-way valve, port A of the four-way valve, and port A of the three-way valve are closed, and the first and second air pumps stop working. The voice prompt "Gas washing is completed" is heard. The voice prompt "Gas washing is completed, please proceed to the next operation!"

[0194] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some or all of the technical features therein. These modifications or replacements do not deviate the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present invention, and they should all be included in the scope of the claims and description of the present invention.

Claims

1. A device for collecting exhaled gas in stages, characterized in that: Including host system and power module; The host system includes a gas drying module, an information interaction module, a gas phased acquisition module, a main control module and a data processing module; The gas drying module is used to absorb water vapor in the exhaled gas and reduce the humidity in the collected gas; The information interaction module includes an information input module and an information output module; The information input module includes a voice input module and a display input module; The information output module includes a voice output module and a display output module; According to the different components and concentrations of exhaled gas, the exhalation process is divided into three stages: mixed waste gas, dead space gas and alveolar gas. The information input module inputs the basic information of the subject and the exhaled breath collection mode through the touch screen or voice input module; The exhaled gas collection modes include ambient gas collection, dead space gas collection, alveolar gas collection, simultaneous classification and collection of ambient gas and dead space gas, simultaneous classification and collection of ambient gas and alveolar gas, simultaneous classification and collection of dead space gas and alveolar gas, and simultaneous classification and collection of ambient gas, dead space gas and alveolar gas; The information output module outputs prompt information and vital capacity test results through the touch screen and audio; The gas phased collection module is used to perform the gas collection process; The main control module includes a gas stage identification module, a gas collection determination module and a monitoring module; The gas phase identification module is used to identify the phase of the exhaled gas; The gas sampling determination module is used to determine whether the subject is in the exhalation state; The monitoring module is used to monitor the conditions at the exhalation port and the port requiring gas collection during exhalation; The data processing module is used to process the calculation process during the gas collection process; The power module includes a charging device and a battery. The charging device supplies power to the exhaled gas collection device in stages and charges the battery. When the charging device is not working, the battery supplies power to the exhaled gas collection device in stages. The information input module is used to select a gas collection mode, and the main control module controls the gas phased collection module according to the selected gas collection mode to complete the collection of exhaled gas in the selected phase.

2. The device for collecting exhaled gas in stages according to claim 1, characterized in that: The gas phase identification module includes a flow meter and a gas sensor module, and the gas sensor module includes an oxygen sensor module and a carbon dioxide sensor module; The gas phase identification module reads the flow meter airflow data, and the gas phase identification module reads the gas concentration values ​​measured by the oxygen sensor module and the carbon dioxide sensor module respectively. and The data processing module calculates the ratio of carbon dioxide concentration to oxygen concentration as , The calculation formula is as follows: in, is the ratio of carbon dioxide concentration to oxygen concentration, The gas concentration value measured by the oxygen sensor module. Gas concentration value measured by the carbon dioxide sensor module.

3. The device for collecting exhaled gas in stages according to claim 2, characterized in that: The gas phased collection module includes: a disposable mouthpiece, a first one-way valve, a first air pump, a three-way valve, a second air pump and a four-way valve; According to the exhaled breath collection mode selected by the information input module, the main control module controls the opening and closing sequence of the pumps and valves in the gas staged collection module to achieve staged collection of gas types matching the selected exhaled breath collection mode. The pumps and valves are connected by Teflon tubes.

4. The device for collecting exhaled gas in stages according to claim 3, characterized in that: The gas collection determination module reads the flow rate VL of the flow meter; When the flow rate of the flow meter is lower than the threshold value KL, the system is determined to be in the non-gas collection mode, all pump valves are closed, and all gas collection processes of the system are stopped; When the flow rate of the flow meter is higher than KL, it is determined that the system is in gas collection mode and the gas collection process is started.

5. The device for collecting exhaled gas in stages according to claim 4, characterized in that: The monitoring module includes a mouthpiece installation monitoring module, an air bag installation monitoring module and an air bag inflation monitoring module; The mouthpiece installation monitoring module is used to monitor the installation status of the disposable mouthpiece, and the mouthpiece installation monitoring module includes the exhalation port and an indicator light. When air collection begins, the indicator light at the exhalation port flashes to prompt the installation of the disposable mouthpiece. After the disposable mouthpiece is correctly installed, the indicator light at the exhalation port goes out. During the exhaled breath collection process, when the mouthpiece installation monitoring module detects that the disposable mouthpiece is not correctly installed, the indicator light at the exhaled breath port flashes, the voice output module and the display output module prompt that the mouthpiece is not correctly installed, all pump valves are closed, and the exhaled breath collection process is paused. When the disposable mouthpiece is correctly installed, the exhaled breath collection process is resumed; The air bag installation monitoring module is used to monitor the installation status of the air bag during the air collection process at the air collection port required for air collection determined by the exhaled air collection mode, including a first air collection port, a second air collection port, and a third air collection port; wherein the first air collection port is used to collect ambient air, the second air collection port is used to collect dead space air, and the third air collection port is used to collect alveolar gas; the air collection port required refers to the air collection port corresponding to the gas required for collection in the collection stage determined by the exhaled air collection mode; when air collection starts, the indicator light at the air collection port required for air collection flashes, prompting the installation of the air bag. After the air bag is correctly installed, the indicator light at the air collection port required for air collection goes out; During the exhaled breath collection process, when the air bag installation monitoring module detects that the air bag at the port requiring air collection is not correctly installed, the indicator light at the port requiring air collection that the air bag is not correctly installed flashes, and the voice output module and the display output module prompt information that the port requiring air collection is not correctly installed. The exhaled breath collection process is paused until all the air bags at the ports requiring air collection are correctly installed, and then the exhaled breath collection process is resumed. Air bags do not need to be installed at ports not requiring air collection. The air bag inflation monitoring module is used to monitor the output value Pi of the air pressure sensor at the port where air is to be collected during the air collection process, so as to monitor the inflation status of the air bag; the air pressure sensor includes a first air pressure sensor, a second air pressure sensor, and a third air pressure sensor; the first air pressure sensor is located at the first air collection port, and is used to monitor the environmental gas collection status of the first air bag; the second air pressure sensor is located at the second air collection port, and is used to monitor the dead space gas collection status of the second air bag; the third air pressure sensor is located at the third air collection port, and is used to monitor the alveolar gas collection status of the third air bag; when the air bag inflation monitoring module detects that the port where air is to be collected is empty, the air bag is in a state of being filled with air; When the output value Pi of the air pressure sensor at the port is less than the air bag pressure threshold PK, the air circuit is in the air collection state, and the corresponding stage gas is continuously filled into the air bag; when the output value Pi of the air pressure sensor at the port where air collection is required detected by the air bag inflation monitoring module is greater than or equal to the air bag pressure threshold PK, the air circuit is in the stopped air collection state, and the gas in this stage is discharged as exhaust gas after treatment. When the air pressure sensors at all ports where air collection is required are greater than or equal to the air bag pressure threshold PK, the air collection stage ends; there is no need to detect the air bag inflation status at the ports where air collection is not required, and all gas types that do not need to be collected are treated as waste gas and discharged after treatment.

6. The device for collecting exhaled gas in stages according to claim 5, characterized in that: The information interaction module includes an information input module and an information output module; the information input module includes a voice input module and a display input module; The display input module uses a touch screen as a carrier, and the user can click on the touch screen to input personal information such as the subject's name, age, gender, department, hospitalization number, and bed number, and select the exhaled breath collection mode. The user can also click on the touch screen to select voice input, which switches the display input mode to the voice input mode. The voice input module issues commands in the form of voice to input personal information such as the subject's name, age, gender, department, hospitalization number, and bed number, and select the exhaled breath collection mode. The information output module includes a voice output module and a display output module. The voice output module provides voice prompts during the gas collection process. The voice prompts include voice prompts for the type of gas to be collected, voice prompts for the installation of the disposable mouthpiece and the air bag at the port to be collected, voice prompts when the disposable mouthpiece and the air bag at the port to be collected are not correctly installed during the gas collection process, voice prompts when the collection of the type of gas to be collected is completed, voice prompts when the gas collection is finished, and voice broadcasts of vital capacity. The voice prompt information output by the voice output module is all displayed on the display output module.

7. The device for collecting exhaled gas in stages according to claim 6, characterized in that: Also includes a spirometry module; The vital capacity detection module reads the gas flow rate data output by the flow meter and calculates the vital capacity of the person being tested. The calculation formula is as follows: Where r is the airway radius, t is the sampling time, and v is the detected airflow velocity. is a single vital capacity measurement value. is the vital capacity measurement value of this exhalation test, and n is the number of times of blowing in this exhalation collection.

8. The device for collecting exhaled gas in stages according to claim 7, characterized in that: It also includes a sterilization and inactivation module, which includes an airway sterilization and inactivation module and an exhaust sterilization and inactivation module; The airway sterilization and inactivation module includes a plurality of ultraviolet LED lamps, which are dispersed in the airway of the exhaled gas phased collection device to sterilize and inactivate the airway after the gas collection process is completed; The tail gas sterilization and inactivation module includes a plasma generator and sterilization and disinfection particles. The plasma generator is located at the front end of the tail gas sterilization and inactivation module. The sterilization and disinfection particles fill the tube cavity and are used to sterilize and disinfect the tail gas of the gas collection device during the gas collection process before discharging it.

9. The device for collecting exhaled gas in stages according to claim 8, characterized in that: It also includes an information printing module; the information printing module prints a label sticker according to the gas sampling mode selected by the information input module, the number of label stickers printed is determined by the type of gas collected in the gas sampling mode, and the label sticker includes the name, age, gender, department, hospitalization number, bed number, and gas stage information of the subject recorded by the information input module; The label sticker is attached to the surface of the air bag to record the information of the person being tested and the type of gas.

10. The device for collecting exhaled gas in stages according to claim 9, characterized in that: It also includes a mobile payment module, which includes a payment information display module and a payment data transmission module. The payment information display module sends a payment signal to the display output module and displays the QR code information used for payment. When the user completes the payment, the payment data transmission module sends a payment success signal to the main control module; after the main control module receives the payment success signal, the exhaled gas staged collection device starts working.

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