A sleep monitoring device for laboratory mice

Abstract

The present application relates to mouse sleep monitoring technical field, disclose a kind of experimental mouse sleep monitoring device, including monitoring box, the outer wall of monitoring box is slidably installed with box door, the side wall and top end of monitoring box are equidistantly opened with vent, the inner side wall and top end inner wall of monitoring box are installed with filter screen, monitoring box top end middle position is installed with monitoring body, the top end of monitoring box is installed with fan, the bottom end middle position of monitoring box is rotatably installed with support column, the top end of support column is fixedly connected with support seat, and the top end of support seat is installed with rearing unit;The present application is convenient for mouse to be placed while also can be monitored simultaneously, avoid multiple mice to influence each other when monitoring, and four annular arrangement of rearing frame is used, it is convenient to make the mouse inside four rearing frame have same monitoring range and monitoring angle, effectively improve the monitoring stability and monitoring quality of mouse.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of mouse sleep monitoring, in particular to an experimental mouse sleep monitoring device. BACKGROUND

[0002] With the increase of social, environmental and psychological pressure, sleep disorders have become a major public health problem worldwide, among which insomnia can lead to fatigue, low mood or irritability, widespread discomfort and cognitive impairment, and severe insomnia is prone to motor vehicle and workplace accidents, increasing the risk of endocrine metabolic diseases, cardiovascular diseases, mental diseases and neurodegenerative diseases, so the research on insomnia etiology, treatment, etc. has become a hot spot. In animal sleep research, rodents (mice and rats) are mainly used as research objects, because the homeostatic regulation of sleep, circadian rhythm distribution, sensitivity to internal and external factors, response to sleep-wake regulation drugs and neurochemical regulation of humans and rodents are basically similar, suggesting that there are common internal mechanisms in sleep disorders of humans and rodents, so it is necessary to monitor the sleep and wakefulness of rodents.

[0003] When monitoring the sleep of mice, if multiple mice are mixed for monitoring, mutual interference is easy to occur, which will affect the monitoring accuracy, and if they are separated and raised in feeding frames placed in parallel, the monitoring range and monitoring angle of a monitoring device for different mice will be different, which will further reduce the monitoring stability and monitoring quality of each mouse. SUMMARY

[0004] To solve the technical problem that mixed mice are easy to interfere with each other, and that separating and placing them in feeding frames placed in parallel will cause differences in the monitoring range and monitoring angle of a monitoring device for each mouse, thereby reducing the monitoring stability and monitoring quality of each mouse, the present application provides an experimental mouse sleep monitoring device.

[0005] The application adopts the following technical scheme: a mouse sleep monitoring device for experiments, comprising a monitoring box body, a box door slidingly installed on the outer wall of the monitoring box body, ventilation holes equally arranged on the side wall and the top end of the monitoring box body, filter screens installed on the inner side wall and the inner top end wall of the monitoring box body, a monitoring body installed at the middle position of the top end of the monitoring box body, fans equally installed on the top end of the monitoring box body, a support column rotationally installed at the middle position of the bottom end of the monitoring box body, a support seat fixedly connected to the top end of the support column, a feeding unit installed on the top end of the support seat, the feeding unit comprising feeding frames annularly installed on the top end of the support seat and equally arranged, through openings formed in the bottom end of each feeding frame, four feeding frames, a stop ring sleeved on the outer wall of the four feeding frames, plug-in plates equally installed on the top end of the support seat and located inside the stop ring, plug-in slots formed in the bottom end of the feeding frames and sleeved on the outside of the plug-in plates, water tanks arranged at the middle positions of the four feeding frames and connected with the four feeding frames through locking mechanisms, a collection groove formed in the top end of the support seat, a liquid pushing groove formed in one side of the bottom end of the collection groove, a discharge opening formed in one side of the support seat and communicating with the liquid pushing groove, a cleaning assembly arranged in the support seat and connected with the water tanks, and a liquid collecting box arranged below the discharge opening at the bottom end of the support seat.

[0006] As a further improvement of the above scheme, the feeding frame and the net plate are both in a fan-shaped structure, the bottom end inner wall of the feeding frame is provided with a plug hole, the bottom end of the net plate is fixedly connected with a plug rod inserted into the plug hole, and the plug-in plate and the plug-in slot are both in an arc-shaped structure.

[0007] As a further improvement of the above scheme, the outer wall of the monitoring box body is provided with a moving groove, the inner wall of the box door is fixedly connected with a moving seat slidingly arranged in the moving groove, and the longitudinal section of the moving seat and the moving groove is both in a T-shaped structure.

[0008] As a further improvement of the above scheme, the locking mechanism comprises a locking slot formed in the top end of the feeding frame, equally arranged slots formed in the top end of the outer wall of the water tank, a lead screw one rotationally installed on the inner wall of each slot, one end of the lead screw one extending above the water tank, a sliding rod sleeved on the lead screw one and threadedly connected, one end of the sliding rod slidingly contacting the side wall of the slot, a telescopic locking rod sleeved on the other end of the sliding rod, a spring one installed on the inner wall of the telescopic locking rod and connected with one end of the sliding rod, one end of the telescopic locking rod inserted into the locking slot, a limiting piece slidingly connected with the slot arranged on the telescopic locking rod, and the four lead screws one connected through a driving piece.

[0009] As a further improvement of the above-mentioned solution, the limiting piece comprises a stabilizing rod fixed on both sides of the telescopic lock rod, two stabilizing grooves are symmetrically arranged on both sides of the slot, two stabilizing grooves are vertically distributed in staggered positions, and the upper stabilizing groove is arranged close to the first lead screw, the second stabilizing groove is arranged between the two stabilizing grooves, and the second stabilizing groove is arranged obliquely, the two ends of the second stabilizing groove are connected with the close end of the two stabilizing grooves respectively, one end of the stabilizing rod extends into the interior of the stabilizing groove, and the one end of the stabilizing rod is slidable in the interior of the stabilizing groove and the second stabilizing groove.

[0010] As a further improvement of the above-mentioned solution, the driving piece comprises a gear fixed on the top end of the first lead screw, the top end of the water tank is rotatably provided with a gear ring, four gears are arranged on the outside of the gear ring, and the four gears are in meshing connection with the gear ring.

[0011] As a further improvement of the above-mentioned solution, the cleaning assembly comprises a scraping mechanism, a liquid discharge mechanism and a cleaning unit, the cleaning unit comprises a flow guide cylinder installed at the bottom end of the water tank, the flow guide cylinder is in communication with the water tank, the bottom end of the flow guide cylinder is provided with a communication ring, the outer wall of the communication ring is provided with water spray pipes at equal distances, there are four water spray pipes, and the four water spray pipes are arranged below the contact position of adjacent breeding frames, so that the urine on the screen can be prevented from falling on the top end of the water spray pipe.

[0012] As a further improvement of the above-mentioned solution, the scraping mechanism comprises a ring-shaped cylinder fixed on the middle position of the top end of the collecting groove, a rotating shaft is rotatably installed in the interior of the ring-shaped cylinder, the rotating shaft penetrates through the communication ring and the flow guide cylinder and is rotatably connected with the bottom end of the water tank, a groove is arranged below the ring-shaped cylinder and in communication with the liquid pushing groove on the support seat, a double-shaft motor is installed in the interior of the groove, one output shaft of the double-shaft motor is connected with the rotating shaft, the other output shaft of the double-shaft motor is connected with a conical gear one arranged in the interior of the groove, a connecting seat is fixedly installed on the rotating shaft, two scraper two are symmetrically arranged on the bottom end of the connecting seat and sleeved on the outside of the ring-shaped cylinder, the scraper two is in sliding connection with the inner wall of the collecting groove, and the conical gear one is connected with the liquid discharge mechanism.

[0013] As a further improvement of the above-mentioned scheme, the liquid discharge mechanism comprises a screw rod two rotatably installed in the liquid pushing groove, one end of the screw rod two extends to the inside of the discharge port, the other end of the screw rod two is fixedly connected with a conical gear two meshing with the conical gear one, a sliding plate is threadedly sleeved on the screw rod two, the sliding plate is in sliding contact with the inner wall of the liquid pushing groove, a flow guide plate is installed on the top of the liquid pushing groove above the screw rod two, the flow guide plate is smaller than the width of the liquid pushing groove, the width of the liquid pushing groove, the discharge port and the scraper one is equal, which facilitates the sliding contact of the scraper one with the side wall of the liquid pushing groove and the discharge port, and provides convenience for waste liquid discharge, the side surface of the flow guide plate is triangular structure, through the structural arrangement of the flow guide plate, the screw rod two is conveniently shielded, and the waste liquid can be guided, avoiding the contact of the waste liquid with the screw rod two, realizing the protection of the screw rod two, and the bottom end of the sliding plate penetrates the telescopic pushing unit.

[0014] As a further improvement of the above-mentioned scheme, the telescopic pushing unit comprises a lifting plate penetrating into the sliding plate, a scraper one is fixedly connected to the bottom end of the lifting plate, the scraper one is in sliding contact with the inner wall of the liquid pushing groove, a magnetic sheet one is installed on the top end inner wall of the sliding plate, a magnetic sheet two is installed on the top end of the lifting plate, the magnetic sheet one and the magnetic sheet two are magnetically opposite, and the magnetic force generated by the magnetic sheet one and the magnetic sheet two is greater than the elastic force of the spring two, sliding blocks are fixedly connected to the two side top ends of the lifting plate, a sliding channel in sliding connection with the sliding blocks is formed in the inner wall of the sliding plate, the sliding blocks and the sliding channel are connected through the spring two, a limiting rod is fixedly connected to the middle position of the side wall of the lifting plate, two limiting grooves one in sliding connection with the limiting rod are symmetrically formed in the two sides of the sliding plate, two limiting grooves one are symmetrically formed in the inner wall of the liquid pushing groove, the two limiting grooves one are longitudinally parallel, and one end of the two limiting grooves one extends to the side wall of the discharge port, a limiting groove two is formed in the side wall of the liquid pushing groove and communicates with one end of the two limiting grooves one, the two limiting grooves one and the two limiting grooves two form a parallelogram structure, one end of the limiting rod penetrates through the sliding port and extends to the inside of the limiting groove one, and the one end of the limiting rod is slidably arranged in the limiting groove one and the limiting groove two.

[0015] Compared with the prior art, the present application has the following advantages:

[0016] 1、The four feeding frames and the monitoring body are used for conveniently placing and monitoring the mice, avoiding the mutual influence of the mice during monitoring, effectively improving the monitoring efficiency of the mice, and the four feeding frames are arranged in a ring shape, so that the mice in the four feeding frames have the same monitoring range and monitoring angle, effectively improving the monitoring stability and monitoring quality of the mice, solving the problem that the monitoring angle and range of each mouse are inconsistent when the mice are placed in the parallel arranged feeding frames, and effectively improving the synchronous monitoring quality of the mice.

[0017] 2. The locking mechanism design facilitates the limiting of the feeding frame by the insert plate and coordinates with the connection between the feeding frame and the water tank. This prevents the water tank from shifting during the rotation of the scraping mechanism, thus avoiding the displacement of the cleaning unit and effectively preventing urine from falling onto the spray pipe, thereby protecting the spray pipe.

[0018] 3. The design of the scraping mechanism and cleaning unit facilitates the cleaning and scraping of urine that falls into the collection tank. Combined with the design of the drainage mechanism, it is easy to scrape out the accumulated liquid inside the drainage tank, effectively cleaning the urine and solving the problem that urine accumulation in the bottom of the traditional breeding frame can easily affect the quality of sleep monitoring due to the influence of the living environment. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the overall structure of the experimental mouse sleep monitoring device provided in Embodiment 1 of the present invention;

[0020] Figure 2 for Figure 1 Top sectional view of the monitoring enclosure and its door;

[0021] Figure 3 A connection diagram of the feeding unit with its support columns, support bases, locking mechanism, and cleaning components;

[0022] Figure 4 A top view of the feeding unit;

[0023] Figure 5 This is a schematic diagram of the stencil structure;

[0024] Figure 6 for Figure 3 Enlarged structural diagram at point A;

[0025] Figure 7 This is a top sectional view of the support base;

[0026] Figure 8 This is a bottom view of the cleaning unit;

[0027] Figure 9 This is a schematic diagram of the drainage mechanism;

[0028] Figure 10 for Figure 9 Enlarged structural diagram at point B;

[0029] Figure 11 Connection between the feeding unit and the locking mechanism Figure 1 ;

[0030] Figure 12 Connection between the feeding unit and the locking mechanism Figure 2 .

[0031] Main symbol explanation:

[0032] 1, monitoring box; 2, box door; 3, ventilation hole; 4, filter screen; 5, monitoring body; 6, support column; 7, support seat; 8, double-shaft motor; 9, fan; 10, feeding frame; 11, stop ring; 12, through port; 13, net plate; 14, plug-in board; 15, plug-in rod; 16, plug-in slot; 17, collection groove; 18, annular cylinder; 19, liquid pushing groove; 20, discharge port; 21, liquid collection box; 22, rotating shaft; 23, water tank; 24, locking groove; 25, slotted; 26, screw rod one; 27, sliding rod; 28, telescopic locking rod; 29, spring one; 30, stabilizing rod; 31, stabilizing groove one; 32, stabilizing groove two; 33, gear; 34, gear ring; 35, jack; 36, bevel gear one; 37, screw rod two; 38, bevel gear two; 39, sliding plate; 40, limiting groove one; 41, limiting groove two; 42, deflector; 43, lifting plate; 44, scraper one; 45, magnetic sheet one; 46, magnetic sheet two; 47, sliding port; 48, limiting rod; 49, sliding block; 50, slide; 51, spring two; 52, flow guide cylinder; 53, communication ring; 54, water spraying pipe; 55, scraper two; 56, moving seat; 57, moving slot; 58, connection seat. DETAILED DESCRIPTION

[0033] In the following, the application will be further described in conjunction with the drawings and specific embodiments. It should be noted that the following described embodiments or technical features can be combined in any manner to form new embodiments without conflict.

[0034] Embodiment 1:

[0035] Please combine Figure 1 , Figure 3 , Figure 4 , Figure 5 , Figure 10 , Figure 11 and Figure 12The embodiment of the experimental mouse sleep monitoring device, including monitoring box 1, the outer wall of monitoring box 1 is slidably installed with box door 2, the side wall and the top end of monitoring box 1 are equally spaced apart and provided with ventilation hole 3, the inner side wall and the top end inner wall of monitoring box 1 are provided with filter screen 4, monitoring body 5 is installed at the middle position of the top end of monitoring box 1, fan 9 is installed at the top end of monitoring box 1, support column 6 is rotatably installed at the middle position of the bottom end of monitoring box 1, support column 6 is fixedly connected with support seat 7 at the top end, feeding unit is installed at the top end of support seat 7, feeding unit includes feeding frame 10 which is annularly installed at the top end of support seat 7 and is equally arranged, feeding frame 10 is provided with four, the bottom end of feeding frame 10 is provided with through hole 12, support seat 7 is provided with stop ring 11 which is sleeved on the outer wall of four feeding frames 10, plug-in plate 14 is installed at the top end of support seat 7 and is located inside stop ring 11, plug-in groove 16 is formed in the bottom end of feeding frame 10 and is sleeved on the outside of plug-in plate 14, water tank 23 is arranged at the middle position of four feeding frames 10, water tank 23 is connected with four feeding frames 10 through locking mechanism, collecting groove 17 is formed in the top end of support seat 7, push liquid groove 19 is formed in one side of the bottom end of collecting groove 17, discharge port 20 is formed in one side of support seat 7 and is communicated with push liquid groove 19, cleaning assembly is arranged in the inside of support seat 7 and is connected with water tank 23, liquid collecting box 21 is arranged below discharge port 20 at the bottom end of support seat 7, feeding frame 10 and mesh plate 13 are both fan-shaped structures, plug-in hole 35 is formed in the bottom end inner wall of feeding frame 10, plug-in rod 15 is fixedly connected with the bottom end of mesh plate 13 and is inserted into plug-in hole 35, plug-in plate 14 and plug-in groove 16 are both arc-shaped structures;

[0036] The worker places four feeding frames 10 at the top end of the support seat 7, inserts the slots 16 at the bottom end of the four feeding frames 10 into the plugboard 14, and makes the four feeding frames 10 contact the inner wall of the stop ring 11 and the outer wall of the water tank 23, then places the mesh plate 13 inside the feeding frame 10, inserts the plug rod 15 at the bottom end of the mesh plate 13 into the plug hole 35 in the inner wall of the feeding frame 10, realizes the support installation of the mesh plate 13, provides convenience for the later disassembly, replacement and cleaning of the mesh plate 13, and through the design of the mesh plate 13, the urine produced by the mice during the monitoring process can fall through the mesh plate 13 into the collection groove 17, effectively providing convenience for the collection and cleaning of the urine, then puts the mice to be monitored into each feeding frame 10, and through the action of the monitoring body 5, the mice can be conveniently placed separately while being monitored synchronously, effectively improving the monitoring efficiency of multiple mice, and the design solves the problem that multiple mice mixed together affect each other and cause inaccurate sleep monitoring data, then turns on the fan 9, which facilitates the blowing operation inside the monitoring box body 1, realizes the air circulation inside the monitoring box body 1, and the design adopts four annularly arranged feeding frames 10, and the monitoring body 5 is located at the middle position of the top end of the four feeding frames 10, which facilitates the monitoring range and monitoring angle of the monitoring body 5 to the mice inside the four feeding frames 10 to remain consistent, effectively improves the monitoring effect and monitoring quality, solves the problem that the monitoring angle and monitoring range of each mouse are inconsistent when the mice are placed in the feeding frames arranged in parallel, and thus the design effectively improves the synchronous monitoring quality of multiple mice.

[0037] In combination Figure 2 , the outer wall of the monitoring box body 1 is provided with a moving groove 57, the inner wall of the box door 2 is fixedly connected with a moving seat 56 sliding in the moving groove 57, and the longitudinal section of the moving seat 56 and the moving groove 57 is a T-shaped structure; by pushing the box door 2, the box door 2 drives the moving seat 56 to slide in the moving groove 57, and then the box door 2 slides on the outer wall of the monitoring box body 1, realizes the opening and closing of the box door 2 to the monitoring box body 1, and facilitates the replacement of the mice and the cleaning of the feeding frames 10 and the mesh plate 13.

[0038] In combination Figure 6 , Figure 11 and Figure 12The locking mechanism comprises a locking groove 24 formed at the top end of the feeding frame 10, equidistantly formed at the top end of the outer wall of the water tank 23 is a slot 25, the inner wall of the slot 25 is rotatably installed with a lead screw 26, one end of the lead screw 26 extends above the water tank 23, a threaded connection sliding rod 27 is sleeved on the lead screw 26, one end of the sliding rod 27 is in sliding contact with the side wall of the slot 25, the other end of the sliding rod 27 is sleeved with a telescopic lock rod 28, the inner wall of the telescopic lock rod 28 is installed with a spring 29 connected with one end of the sliding rod 27, one end of the telescopic lock rod 28 penetrates into the inside of the locking groove 24, the telescopic lock rod 28 is provided with a limiting piece in sliding connection with the slot 25, the four lead screws 26 are connected through a driving piece, the limiting piece comprises a stabilizing rod 30 fixed on both sides of the telescopic lock rod 28, two stabilizing grooves 31 and 32 are symmetrically formed on both sides of the slot 25, the two stabilizing grooves 31 are vertically distributed in an upper and lower staggered manner, and the upper stabilizing groove 31 is arranged close to the lead screw 26, the stabilizing groove 32 is located between the two stabilizing grooves 31, and the stabilizing groove 32 is arranged obliquely, the two ends of the stabilizing groove 32 are respectively connected with the close end of the two stabilizing grooves 31, one end of the stabilizing rod 30 extends into the inside of the stabilizing groove 31, and the stabilizing rod 30 is slidably arranged in the inside of the stabilizing groove 31 and the stabilizing groove 32, the driving piece comprises a gear 33 fixed on the top end of the lead screw 26, a gear ring 34 is rotatably installed at the top end of the water tank 23, the four gears 33 are located on the outside of the gear ring 34, and the four gears 33 are in meshing connection with the gear ring 34;

[0039] The top end of the support base 7 is provided with a collecting groove 17, and the support base 7 is arranged above the collecting groove 17, so that the inner side of the bottom end of the feeding frame 10 is suspended, and the inner wall of the four feeding frames 10 is in contact with the side wall of the water tank 23, thereby supporting the inner side of the feeding frame 10 by the water tank 23, effectively improving the installation stability of the feeding frame 10. At the same time, the staff rotates the gear ring 34, and the gear ring 34 is in meshing connection with the gear 33, so that the gear 33 rotates, and the four gears 33 rotate in the same direction, and the gear 33 drives the lead screw 26 to rotate. Through the threaded connection between the lead screw 26 and the sliding rod 27 and the sliding relationship between the sliding rod 27 and the inner wall of the slot 25, the sliding rod 27 drives the telescopic lock rod 28 to move downward synchronously, and the telescopic lock rod 28 drives the stabilizing rod 30 to move downward, so that the stabilizing rod 30 slides and moves downward in the upper stabilizing groove 31. When the stabilizing rod 30 moves to the inside of the stabilizing groove 32, the telescopic lock rod 28 moves away from the slot 25 during the downward movement, so that the spring 29 is stretched, and the telescopic lock rod 28 moves to the outside of the slot 25. Then, when the bottom end of the telescopic lock rod 28 moves to the upper side of the lock slot 24, the stabilizing rod 30 moves to the lower stabilizing groove 31 as the sliding rod 27 continues to move downward, so that the telescopic lock rod 28 moves vertically downward, and the telescopic lock rod 28 is inserted into the inside of the lock slot 24, thereby locking the water tank 23 and the feeding frame 10. The design facilitates the positioning of the feeding frame 10 by the plugboard 14 and the connection of the feeding frame 10 and the water tank 23, avoids the deflection of the water tank 23 caused by the cleaning unit during the rotation of the scraping mechanism, effectively avoids the urine falling on the water pipe 54, and thereby maintains the cleanliness of the water pipe 54.

[0040] In combination Figure 8 The cleaning assembly comprises a scraping mechanism, a liquid discharge mechanism and a cleaning unit. The cleaning unit comprises a flow guide cylinder 52 mounted at the bottom end of the water tank 23, the flow guide cylinder 52 being in communication with the water tank 23. A communication ring 53 is mounted at the bottom end of the flow guide cylinder 52. The outer wall of the communication ring 53 is equidistantly provided with four water pipes 54. It should be noted that the inner wall of the water tank 23 is provided with a valve at the bottom end, so that the liquid in the water tank 23 can be sprayed out after the valve is opened. The four water pipes 54 are arranged below the contact position of the adjacent feeding frames 10. Through this position design, the urine on the screen plate 13 can be prevented from falling on the top end of the water pipe 54.

[0041] In the monitoring process, the staff open the valve inside the water tank 23 at irregular intervals, after the valve is opened, the water inside the water tank 23 will enter the flow guide cylinder 52, then the water inside the flow guide cylinder 52 will enter the communication ring 53, then the water will enter the water spray pipe 54, the water inside the water spray pipe 54 will be sprayed to the inside of the collecting groove 17, which is convenient for flushing the urine falling into the collecting groove 17 through the mesh plate 13, and also can spray the top end of the scraper two 55 to realize flushing, realize the cleaning of the scraper two 55.

[0042] With Figure 7 The scraping mechanism comprises an annular cylinder 18 fixedly connected to the middle position of the top end of the collecting groove 17, a rotating shaft 22 rotatably installed in the annular cylinder 18, the rotating shaft 22 penetrating through the communication ring 53 and the flow guide cylinder 52 and being rotatably connected with the bottom end of the water tank 23, a groove located below the annular cylinder 18 and communicating with the liquid pushing groove 19 is formed in the support seat 7, a double-shaft motor 8 is installed in the groove, one output shaft of the double-shaft motor 8 is connected with the rotating shaft 22, the other output shaft of the double-shaft motor 8 is connected with a conical gear one 36 located in the groove, a connecting seat 58 is fixedly installed on the rotating shaft 22, the bottom end of the connecting seat 58 is symmetrically installed with a scraper two 55 sleeved outside the annular cylinder 18, the scraper two 55 is slidably connected with the inner wall of the collecting groove 17, and the conical gear one 36 is connected with the liquid discharging mechanism.

[0043] In the monitoring process, the staff open the valve inside the water tank 23 at irregular intervals, after the valve is opened, the water inside the water tank 23 will enter the flow guide cylinder 52, then the water inside the flow guide cylinder 52 will enter the communication ring 53, then the water will enter the water spray pipe 54, the water inside the water spray pipe 54 will be sprayed to the inside of the collecting groove 17, which is convenient for flushing the urine falling into the collecting groove 17 through the mesh plate 13, and also can spray the top end of the scraper two 55 to realize flushing, realize the cleaning of the scraper two 55.

[0044] With Figure 9 And Figure 10The liquid discharging mechanism comprises a screw rod two 37 rotatably installed in the interior of the liquid pushing groove 19, one end of the screw rod two 37 extending to the interior of the discharge port 20, the other end of the screw rod two 37 being fixedly connected with a conical gear two 38 meshingly connected with the conical gear one 36, the screw rod two 37 being threadedly sleeved with a sliding plate 39, the sliding plate 39 being in sliding contact with the inner wall of the liquid pushing groove 19, the top of the liquid pushing groove 19 being provided with a flow guide plate 42 located above the screw rod two 37, the flow guide plate 42 being smaller than the width of the liquid pushing groove 19, the width of the liquid pushing groove 19, the discharge port 20 and the scraper one 44 being equal, so as to facilitate the sliding contact of the scraper one 44 with the side walls of the liquid pushing groove 19 and the discharge port 20, and provide convenience for the waste liquid discharge, the side of the flow guide plate 42 being triangular in structure, the structure of the flow guide plate 42 facilitating the shielding of the screw rod two 37, so as to facilitate the flow guiding operation of the waste liquid, avoid the contact of the waste liquid with the screw rod two 37, and realize the protection of the screw rod two 37, the bottom end of the sliding plate 39 being provided with a telescopic pushing unit, the telescopic pushing unit comprising a lifting plate 43 inserted into the interior of the sliding plate 39, the bottom end of the lifting plate 43 being fixedly connected with the scraper one 44, the scraper one 44 being in sliding contact with the inner wall of the liquid pushing groove 19, the top end inner wall of the sliding plate 39 being provided with a magnetic sheet one 45, the top end of the lifting plate 43 being provided with a magnetic sheet two 46, the magnetic sheet one 45 and the magnetic sheet two 46 being magnetically opposite, the magnetic force generated by the magnetic sheet one 45 and the magnetic sheet two 46 being greater than the elastic force of a spring two 51, both sides of the top end of the lifting plate 43 being fixedly connected with sliding blocks 49, the inner wall of the sliding plate 39 being provided with sliding channels 50 slidably connected with the sliding blocks 49, the sliding blocks 49 and the sliding channels 50 being connected through the spring two 51, the side wall of the lifting plate 43 being fixedly connected with a limiting rod 48 at the middle position, the two sides of the sliding plate 39 being symmetrically provided with sliding openings 47 slidably connected with the limiting rod 48, the inner wall of the liquid pushing groove 19 being provided with two limiting grooves one 40 symmetrically, the two limiting grooves one 40 being longitudinally and parallelly arranged, one end of each of the two limiting grooves one 40 extending to the side wall of the discharge port 20, the side wall of the liquid pushing groove 19 being provided with a limiting groove two 41 in communication with one end of the two limiting grooves one 40 close to each other, the two limiting grooves one 40 and the two limiting grooves two 41 forming a parallelogram structure, one end of the limiting rod 48 extending to the interior of the limiting groove one 40 through the sliding opening 47, and the one end of the limiting rod 48 being slidable in the interiors of the limiting groove one 40 and the limiting groove two 41;

[0045] When the scraper 2 is rotating, it will push the urine and waste liquid in the collection groove 17 to the liquid pushing groove 19 and the top of the flow guide plate 42, and then under the guidance of the flow guide plate 42, the waste liquid will fall into the liquid pushing groove 19, and then through the action of the discharge port 20, the waste liquid will fall into the liquid collecting box 21 through the discharge port 20. At the same time, the operation of the double-shaft motor 8 will drive the conical gear 1 36 to rotate, and through the meshing connection relationship between the conical gear 1 36 and the conical gear 2 38, the conical gear 2 38 will drive the lead screw 2 37 to rotate. Through the threaded connection relationship between the lead screw 2 37 and the sliding plate 39 and the sliding connection relationship between the sliding plate 39 and the side wall of the liquid pushing groove 19, the sliding plate 39 will drive the lifting plate 43 and the scraper 1 44 to move horizontally. When approaching the discharge port 20, the limiting rod 48 will slide in the limiting groove 1 40 below, and the scraper 1 44 will scrape the bottom and side wall of the liquid pushing groove 19, facilitating the movement of the residual liquid to the discharge port 20. With the continuous horizontal movement of the lifting plate 43, the limiting rod 48 will move to the limiting groove 2 41. Since the limiting groove 2 41 is designed to be inclined, the limiting rod 48 will drive the lifting plate 43, the scraper 1 44 and the magnetic sheet 2 46 to move upwards, and then the sliding block 49 will move upwards in the slide 50, and the spring 2 51 will be stretched. When the limiting rod 48 moves to the top of the limiting groove 2 41, the magnetic sheet 2 46 is connected with the magnetic sheet 1 45 by adsorption, and then the double-shaft motor 8 is started in reverse rotation, which will make the lead screw 2 37 reverse, and the sliding plate 39 moves reversely. Since the adsorption force of the magnetic sheet 1 45 and the magnetic sheet 2 46 is greater than the elastic force of the spring 2 51, the limiting rod 48 will continue to move horizontally in the limiting groove 1 40 above, and then the lifting plate 43 and the scraper 1 44 will be separated from the bottom of the liquid pushing groove 19 during the movement of the ring cylinder 1 8. With the continuous movement of the sliding plate 39, the limiting rod 48 will slide into the limiting groove 2 41, and the magnetic sheet 2 46 will be separated from the magnetic sheet 1 45, and then the scraper 1 44 will be in contact with the bottom of the liquid pushing groove 19 again, facilitating the discharge and cleaning operation of the liquid in the liquid pushing groove 19, effectively realizing the cleaning of the urine, and solving the problem that the traditional breeding frame 10 is prone to urine accumulation at the bottom of the sealing, which will reduce the sleep monitoring quality due to the influence of the living environment.

[0046] The implementation principle of the experimental mouse sleep monitoring device in the embodiment of the application is as follows: the workers place four feeding frames 10 at the top end of the support seat 7, make the insertion grooves 16 at the bottom end of the four feeding frames 10 penetrate the insertion plates 14, make the four feeding frames 10 contact the inner wall of the stop ring 11, and make the four feeding frames 10 contact the outer wall of the water tank 23, then place the mesh plate 13 inside the feeding frame 10, make the insertion rod 15 at the bottom end of the mesh plate 13 penetrate the insertion hole 35 in the inner wall of the feeding frame 10, realize the support installation of the mesh plate 13, provide convenience for the later disassembly, replacement and cleaning of the mesh plate 13, at the same time, through the design of the mesh plate 13, the urine generated by the mice in the monitoring process can fall into the collection groove 17 through the mesh plate 13, effectively providing convenience for the urine collection and cleaning, then put the mice to be monitored into each feeding frame 10, through the action of the monitoring body 5, the mice can be conveniently placed separately and can also be monitored synchronously, effectively improving the monitoring efficiency of multiple mice, at the same time, the design solves the problem that the mixed placement of multiple mice causes the sleep monitoring data to be inaccurate due to the mutual influence, then start the fan 9, conveniently perform the blowing operation on the inside of the monitoring box body 1, realize the air circulation in the inside of the monitoring box body 1, the design adopts four annularly arranged feeding frames 10, and the monitoring body 5 is located at the middle position of the top end of the four feeding frames 10, the monitoring range and the monitoring angle of the monitoring body 5 to the mice in the four feeding frames 10 are kept consistent, effectively improving the monitoring effect and the monitoring quality, solving the problem that the monitoring angle and the monitoring range of each mouse are inconsistent when the mice are placed in the feeding frames arranged in parallel, and further effectively improving the synchronous monitoring quality of multiple mice;

[0047] The top end of the support base 7 is provided with a collecting groove 17, and the support base 7 is arranged above the collecting groove 17, so that the inner side of the bottom end of the feeding frame 10 is suspended, and the inner walls of the four feeding frames 10 are in contact with the side walls of the water tank 23, thereby supporting the inner side of the feeding frame 10 by the water tank 23, effectively improving the installation stability of the feeding frame 10. At the same time, the staff rotates the gear ring 34, and the gear ring 34 is connected with the gear 33 in meshing relationship, so that the gear 33 rotates, and the four gears 33 rotate in the same direction, and the gear 33 drives the lead screw 26 to rotate. Through the threaded connection relationship between the lead screw 26 and the sliding rod 27 and the sliding relationship between the sliding rod 27 and the inner wall of the slot 25, the sliding rod 27 drives the telescopic lock rod 28 to move downward synchronously, and the telescopic lock rod 28 drives the stabilizing rod 30 to move downward, so that the stabilizing rod 30 slides and moves downward in the upper stabilizing groove 31. When the stabilizing rod 30 moves to the inside of the stabilizing groove 32, the telescopic lock rod 28 moves away from the slot 25 during the downward movement, so that the spring 29 is stretched, and the telescopic lock rod 28 moves to the outside of the slot 25. Then, when the bottom end of the telescopic lock rod 28 moves to the upper side of the lock slot 24, the stabilizing rod 30 moves to the lower stabilizing groove 31 as the sliding rod 27 continues to move downward, so that the telescopic lock rod 28 moves vertically downward, and the telescopic lock rod 28 is inserted into the inside of the lock slot 24, thereby locking the water tank 23 and the feeding frame 10. The design facilitates the positioning of the feeding frame 10 by the plug-in board 14 and the connection of the feeding frame 10 and the water tank 23, avoids the deflection of the water tank 23 caused by the rotation of the scraping mechanism, and effectively avoids the urine from falling on the water spray pipe 54, thereby maintaining the cleanliness of the water spray pipe 54.

[0048] During monitoring, the staff opens the valve in the water tank 23 from time to time. After the valve is opened, the water in the water tank 23 enters the flow guide cylinder 52, and then the water in the flow guide cylinder 52 enters the communication ring 53, and then the water enters the water spray pipe 54. The water in the water spray pipe 54 is sprayed into the inside of the collecting groove 17, which is convenient for washing the urine falling into the collecting groove 17, and also can spray the top end of the scraper 55 to realize washing, thereby realizing cleaning of the scraper 55.

[0049] When the scraper 2 is rotating, it pushes the urine and waste liquid in the collecting groove 17 to the liquid pushing groove 19 and the top end of the flow guide plate 42, and then under the guidance of the flow guide plate 42, the waste liquid falls into the liquid pushing groove 19, and through the action of the discharge port 20, the waste liquid falls into the liquid collecting box 21 through the discharge port 20. At the same time, the operation of the double-shaft motor 8 drives the conical gear 1 36 to rotate, and through the meshing connection relationship between the conical gear 1 36 and the conical gear 2 38, the conical gear 2 38 drives the lead screw 2 37 to rotate, and through the threaded connection relationship between the lead screw 2 37 and the sliding plate 39 and the sliding connection relationship between the sliding plate 39 and the side wall of the liquid pushing groove 19, the sliding plate 39 drives the lifting plate 43 and the scraper 1 44 to move horizontally, and when approaching the discharge port 20, the limiting rod 48 slides in the limiting groove 1 40 below, and the scraper 1 44 scrapes the bottom end and the side wall of the liquid pushing groove 19, facilitating the movement of the residual liquid to the discharge port 20. With the continuous horizontal movement of the lifting plate 43, the limiting rod 48 moves to the limiting groove 2 41, and due to the inclined design of the limiting groove 2 41, the limiting rod 48 drives the lifting plate 43, the scraper 1 44 and the magnetic sheet 2 46 to move upward, and then the sliding block 49 moves upward in the slide 50, and the spring 2 51 is stretched. When the limiting rod 48 moves to the top end of the limiting groove 2 41, the magnetic sheet 2 46 is connected with the magnetic sheet 1 45, and then the double-shaft motor 8 is started in the reverse direction, which reverses the lead screw 2 37 and moves the sliding plate 39 in the reverse direction. Due to the fact that the adsorption force of the magnetic sheet 1 45 and the magnetic sheet 2 46 is greater than the elastic force of the spring 2 51, the limiting rod 48 continues to move horizontally in the limiting groove 1 40 above, and then the lifting plate 43 and the scraper 1 44 are separated from the bottom end of the liquid pushing groove 19 during the movement of the lifting plate 43 and the scraper 1 44 approaching the annular cylinder 18. With the continuous movement of the sliding plate 39, the limiting rod 48 slides into the limiting groove 2 41, and the magnetic sheet 2 46 is separated from the magnetic sheet 1 45, and then the scraper 1 44 contacts the bottom end of the liquid pushing groove 19 again, facilitating the discharge and cleaning operation of the liquid in the liquid pushing groove 19, effectively realizing the cleaning of the urine and solving the problem that the traditional feeding frame 10 is prone to urine accumulation at the bottom, which affects the sleep monitoring quality.

[0050] The above embodiments are only preferred embodiments of the present application, and cannot be used to limit the protection scope of the present application. Any non-essential changes and replacements made by those skilled in the art on the basis of the present application shall fall within the protection scope of the present application.

Claims

1. An experimental mouse sleep monitoring apparatus, characterized by, The utility model provides a kind of monitoring box, the outer wall of monitoring box is slidably installed with box door, the side wall and top end of monitoring box are equidistantly opened with ventilation hole, the inner side wall and top end inner wall of monitoring box are installed with filter screen, monitoring box is installed with monitoring body in the middle position of top end, monitoring box is installed with fan in top end equidistance, monitoring box is rotatably installed with support column in the middle position of bottom end, support column is fixedly connected with support seat in top end, support seat is installed with breeding unit in top end, breeding unit includes annular installation in the top end of support seat and equidistance arrangement feeding frame, the bottom end of feeding frame is opened with pass, feeding frame is equipped with four, support seat is equipped with stop ring in the outer wall of four feeding frames, support seat is installed with plugboard in the inside of stop ring equidistance in top end, feeding frame is opened with the insertion slot in the outside of plugboard in bottom end, the middle position of four feeding frames is equipped with water tank, water tank is connected between four feeding frames by locking mechanism, support seat is opened with collection groove in top end, the bottom end of collection groove is opened with liquid pushing groove in one side, the side of support seat is opened with excretory opening being connected with liquid pushing groove, the inside of support seat is equipped with cleaning assembly being connected with water tank, the bottom end of support seat is equipped with liquid collecting box being located below excretory opening, net board is placed in the inside of feeding frame; The locking mechanism includes a lock slot opened in the top end of the feeding frame, the outer wall top end of the water tank is equidistantly opened with a slot, the inner wall of the slot is rotatably installed with a lead screw one, one end of the lead screw one extends above the water tank, a threaded connection sliding rod is sleeved on the lead screw one, one end of the sliding rod is in sliding contact with the side wall of the slot, the other end of the sliding rod is sleeved with a telescopic lock rod, a spring one connected with one end of the sliding rod is installed on the inner wall of the telescopic lock rod, one end of the telescopic lock rod penetrates into the inside of the lock slot, a limiting piece in sliding connection with the slot is provided on the telescopic lock rod, the four lead screws one are connected by a driving piece; The limiting piece includes stabilizing rods fixedly connected to the two sides of the telescopic lock rod, two stabilizing grooves one and two are symmetrically opened on the two sides of the slot, the two stabilizing grooves one are vertically distributed in an upper and lower staggered manner, and the upper stabilizing groove one is arranged close to the lead screw one, the stabilizing groove two is between the two stabilizing grooves one, and the stabilizing groove two is arranged obliquely, the two ends of the stabilizing groove two are respectively in communication with the close end of the two stabilizing grooves one, one end of the stabilizing rod extends into the inside of the stabilizing groove one, and the one end of the stabilizing rod is slidable in the inside of the stabilizing groove one and the stabilizing groove two.

2. The mouse sleep monitoring apparatus for experiments of claim 1, wherein, The feeding frame and the net board are both fan-shaped structures, the bottom end inner wall of the feeding frame is opened with a plug hole, the bottom end of the net board is fixedly connected with a plug rod penetrating into the inside of the plug hole, the plug plate and the plug slot are both arc-shaped structures.

3. The mouse sleep monitoring apparatus for experiments of claim 1, wherein, The outer wall of the monitoring box is opened with a moving slot, the inner wall of the box door is fixedly connected with a moving seat sliding in the inside of the moving slot, the longitudinal section of the moving seat and the moving slot is T-shaped structure.

4. The mouse sleep monitoring apparatus for experiments of claim 1, wherein, The driving piece includes a gear fixedly connected to the top end of the lead screw one, a gear ring is rotatably installed on the top end of the water tank, the four gears are located on the outside of the gear ring, and the four gears are in meshing connection with the gear ring.

5. The mouse sleep monitoring apparatus for experiments of claim 1, wherein, The cleaning assembly comprises a scraping mechanism, a liquid discharging mechanism and a cleaning unit, the cleaning unit comprises a flow guide cylinder mounted at the bottom end of the water tank, the flow guide cylinder is communicated with the water tank, a communication ring is mounted at the bottom end of the flow guide cylinder, a plurality of water spraying pipes are equidistantly mounted on the outer wall of the communication ring, and the four water spraying pipes are arranged below the contact position of adjacent feeding frames.

6. The mouse sleep monitoring apparatus for experiments as claimed in claim 5, wherein, The scraping mechanism comprises an annular cylinder fixedly connected to the middle position of the top end of the collecting groove, a rotating shaft is rotatably mounted in the annular cylinder, a groove is formed in the supporting seat and located below the annular cylinder and communicated with the liquid pushing groove, a double-shaft motor is mounted in the groove, one of the output shafts of the double-shaft motor is connected with the rotating shaft, the other output shaft of the double-shaft motor is connected with a conical gear one located in the groove, a connecting seat is fixedly mounted on the rotating shaft, two scraper plates two are symmetrically mounted at the bottom end of the connecting seat and sleeved on the outside of the annular cylinder, the scraper plates two are slidably connected with the inner wall of the collecting groove, and the conical gear one is connected with the liquid discharging mechanism.

7. The mouse sleep monitoring apparatus for experiments of claim 6, wherein, The liquid discharging mechanism comprises a screw rod two rotatably mounted in the liquid pushing groove, one end of the screw rod two extends into the inside of the discharge port, the other end of the screw rod two is fixedly connected with a conical gear two engaged with the conical gear one, a sliding plate is threadedly sleeved on the screw rod two and slidably contacts with the inner wall of the liquid pushing groove, a flow guide plate is mounted on the top of the liquid pushing groove and located above the screw rod two, the width of the flow guide plate is smaller than that of the liquid pushing groove, the side surface of the flow guide plate is triangular, and the bottom end of the sliding plate penetrates a telescopic pushing unit.

8. The mouse sleep monitoring apparatus for experiments of claim 7, wherein, The telescopic pushing unit comprises a lifting plate penetrating into the sliding plate, a scraper plate one is fixedly connected to the bottom end of the lifting plate and slidably contacts with the inner wall of the liquid pushing groove, a magnetic sheet one is mounted on the top end inner wall of the sliding plate, a magnetic sheet two is mounted on the top end of the lifting plate, the magnetic sheet one and the magnetic sheet two are magnetically opposite, the magnetic force generated by the magnetic sheet one and the magnetic sheet two is greater than the elastic force of the spring two, sliding blocks are fixedly connected to the two top ends of the lifting plate, a sliding channel slidably connected with the sliding blocks is formed in the inner wall of the sliding plate, the sliding blocks are connected by the spring two, a limiting rod is fixedly connected to the middle position of the side wall of the lifting plate, two limiting grooves one are symmetrically formed in the inner wall of the liquid pushing groove and longitudinally arranged in parallel, one end of each of the two limiting grooves one extends to the side wall of the discharge port, a limiting groove two is formed in the side wall of the liquid pushing groove and communicated with one end of the two limiting grooves one, the two limiting grooves one and the two limiting grooves two form a parallelogram structure, one end of the limiting rod penetrates through the sliding port and extends into the inside of the limiting groove one, and the one end of the limiting rod is slidably arranged in the limiting groove one and the limiting groove two.

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