A method and device for detecting an optical transmission path in a near-infrared brain function imaging device

Abstract

The present application relates to the technical field of near-infrared device detection, and provides a method and device for detecting an optical transmission path in a near-infrared brain function imaging device. The method includes obtaining light attenuation intensity calibration data of a measurement phantom, wherein the measurement phantom is used to simulate the attenuation of incident light in an object; obtaining the initial light intensity detection result of the outgoing light emitted from the measurement phantom after the incident light enters the measurement phantom detection environment; determining the standard light intensity detection result of the optical transmission path in the standard phantom detection environment based on the initial light intensity detection result and the light attenuation intensity calibration data of the measurement phantom; comparing the standard light intensity detection result with the standard light intensity range to determine the detection result of the optical transmission path in the near-infrared brain function imaging device. In this way, the credibility of the detection result of the performance of the optical transmission path of the near-infrared brain function imaging device using the measurement phantom can be improved.

Description

Technical Field

[0001] The present application relates to the technical field of near-infrared device detection, and in particular to a method and device for detecting an optical transmission path in a near-infrared brain function imaging device. Background Art

[0002] Near-infrared brain function imaging technology uses near-infrared light to detect the hemodynamic response in brain tissue to indirectly reflect the neuronal activity and its changing patterns in local brain tissue. Near-infrared brain function imaging equipment includes light source, cables, transmitting probe (the light source can be set in the transmitting probe), receiving probe, light receiving part and other light transmission related components. These components can constitute an optical transmission path for transmitting near-infrared light to the brain and / or an optical transmission path for receiving near-infrared light from the brain. The performance of the optical transmission path in the near-infrared brain function imaging equipment will directly affect the detection results of the equipment.

[0003] After using the near-infrared brain function imaging device for a period of time, in order to ensure the performance of the device, engineers need to use testing equipment to regularly test it to evaluate its performance. In addition, when the near-infrared brain function imaging device fails, it also needs to be tested with testing equipment to find out the cause of the failure.

[0004] However, due to differences in the models, manufacturers, production batches, manufacturing processes, etc. of the detection equipment, there will be certain deviations in the detection results of the optical transmission pathway in the near-infrared brain function imaging equipment by each detection equipment. Even if the detection equipment has the same structure, there will be certain deviations when it is manufactured using the same manufacturing process, which will lead to certain deviations in the detection results of the optical transmission pathway in the near-infrared brain function imaging equipment. The near-infrared light emitted by the near-infrared brain function imaging equipment to the brain and the near-infrared light received from the brain are both relatively weak. In particular, the near-infrared light will be absorbed and scattered after entering the brain tissue, and the near-infrared light emitted from the brain through the brain tissue is even weaker (i.e., the near-infrared light received from the brain), and its optical power is at the picowatt (W) level. Therefore, this field has very high requirements on the performance of the optical transmission pathway in the near-infrared brain function imaging equipment. How to accurately detect the performance of the optical transmission pathway in the near-infrared brain function imaging equipment has also become a problem to be urgently solved in this field. Summary of the invention

[0005] The present application is proposed to solve the above technical problems existing in the prior art. The present application aims to provide a method and device for detecting an optical transmission path in a near-infrared brain function imaging device, which can solve the problem that the performance of the optical transmission path of the near-infrared brain function imaging device cannot be accurately detected due to individual differences of the measurement phantom, and can improve the accuracy of the detection results of the performance of the optical transmission path of the near-infrared brain function imaging device using the measurement phantom.

[0006] According to a first scheme of the present application, a method for detecting an optical transmission path in a near-infrared brain function imaging device is provided, wherein the near-infrared brain function imaging device has an optical transmission path for transmitting near-infrared light to an object and / or transmitting near-infrared light from an object, and the method comprises: obtaining light attenuation intensity calibration data of a measurement phantom, wherein the measurement phantom is used to simulate the attenuation of incident light in an object; obtaining an initial light intensity detection result of an outgoing light emitted from the measurement phantom after the incident light enters a detection environment of the measurement phantom; determining a standard light intensity detection result of the optical transmission path in a standard phantom detection environment based on the initial light intensity detection result and the light attenuation intensity calibration data of the measurement phantom; and comparing the standard light intensity detection result with a standard light intensity range to determine a detection result of the optical transmission path in the near-infrared brain function imaging device.

[0007] According to a second scheme of the present application, there is provided a device for detecting an optical transmission path in a near-infrared brain function imaging device, wherein the near-infrared brain function imaging device has an optical transmission path for transmitting near-infrared light to an object and / or receiving and transmitting near-infrared light from an object; the device comprises a processing unit, wherein the processing unit is configured to: obtain light attenuation intensity calibration data of a measurement phantom, wherein the measurement phantom is used to simulate the attenuation of incident light in an object; obtain an initial light intensity detection result of an outgoing light emitted from the measurement phantom after the incident light enters a detection environment of the measurement phantom;

[0008] Based on the initial light intensity detection result and the light attenuation intensity calibration data of the measurement phantom, the standard light intensity detection result of the optical transmission path under the standard phantom detection environment is determined; the standard light intensity detection result is compared with the standard light intensity range to determine the detection result of the optical transmission path in the near-infrared brain function imaging device.

[0009] According to a third scheme of the present application, a computer-readable storage medium is provided, wherein the computer-readable storage medium stores a computer program, and when the computer program is executed by a processing device, the following steps are performed: obtaining light attenuation intensity calibration data of a measurement phantom, wherein the measurement phantom is used to simulate the attenuation of incident light in an object; obtaining an initial light intensity detection result of an outgoing light emitted from the measurement phantom after the incident light enters a detection environment of the measurement phantom; determining a standard light intensity detection result of the optical transmission path in a standard phantom detection environment based on the initial light intensity detection result and the light attenuation intensity calibration data of the measurement phantom; and comparing the standard light intensity detection result with a standard light intensity range to determine a detection result of the optical transmission path in the near-infrared brain function imaging device.

[0010] Compared with the prior art, the beneficial effects of the embodiments of the present application are:

[0011] The method for detecting the optical transmission path in the near-infrared brain function imaging device provided in the embodiment of the present application converts the initial light intensity detection result of the optical transmission path in the measurement phantom detection environment into the standard light intensity detection result in the standard phantom detection environment based on the obtained light attenuation intensity calibration data of the measurement phantom, so as to correct the initial light intensity detection result, and can eliminate the adverse effect of the problem of the measurement phantom itself on the performance of the detection optical transmission path. Based on the detection method provided in the embodiment of the present application, by comparing the standard light intensity detection result obtained after conversion with the standard light intensity range, the standardized detection of the optical transmission path in the near-infrared brain function imaging device is realized, and the accuracy and credibility of the detection result of the performance of the optical transmission path in the near-infrared brain function imaging device is improved.

[0012] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application, it can be implemented in accordance with the contents of the specification. In order to make the above description and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] In the drawings, which are not necessarily drawn to scale, the same reference numerals may describe similar parts in different views. Similar reference numerals with letter suffixes or different letter suffixes may represent different examples of similar components. The accompanying drawings generally illustrate various embodiments by way of example and not by way of limitation, and together with the description and claims, are used to illustrate the disclosed embodiments. Such embodiments are illustrative and exemplary and are not intended to be exhaustive or exclusive embodiments of the present method, apparatus, or non-transitory computer-readable medium having instructions for implementing the method.

[0014] Figure 1 A schematic diagram showing a light transmission path in a near-infrared brain function imaging device according to an embodiment of the present application.

[0015] Figure 2 A flow chart of a method for detecting an optical transmission path in a near-infrared brain function imaging device according to an embodiment of the present application is shown.

[0016] Figure 3 A schematic diagram showing the use of a measurement phantom to detect the performance of an optical transmission path of a near-infrared brain function imaging device according to an embodiment of the present application is shown.

[0017] Figure 4 An interface for displaying first prompt information according to an embodiment of the present application is shown.

[0018] Figure 5 A diagram showing the first probe hole position of the measurement phantom according to an embodiment of the present application is shown.

[0019] Figure 6 A schematic diagram of a collection interface according to an embodiment of the present application is shown.

[0020] Figure 7 A schematic diagram showing a light intensity voltage value according to an embodiment of the present application is shown. DETAILED DESCRIPTION

[0021] In order to enable those skilled in the art to better understand the technical solution of the present application, the present application is described in detail below in conjunction with the accompanying drawings and specific implementation examples. The embodiments of the present application are further described in detail below in conjunction with the accompanying drawings and specific implementation examples, but are not intended to limit the present application.

[0022] The words "first", "second" and similar words used in this application do not indicate any order, quantity or importance, but are only used to distinguish. The words "include" or "comprises" and similar words used in this application mean that the elements before the word include the elements listed after the word, and do not exclude the possibility of covering other elements. In this application, the arrows shown in the figures of each step are only examples of the execution order, not limitations. The technical solution of this application is not limited to the execution order described in the embodiments. The various steps in the execution order can be combined, decomposed, or the order can be changed, as long as the logical relationship of the execution content is not affected.

[0023] All terms (including technical terms or scientific terms) used in this application have the same meaning as those understood by ordinary technicians in the field to which this application belongs, unless otherwise specifically defined. It should also be understood that terms defined in general dictionaries should be interpreted as having a meaning consistent with their meaning in the context of the relevant technology, and should not be interpreted in an idealized or extremely formal sense, unless explicitly defined here. Techniques and equipment known to ordinary technicians in the relevant field may not be discussed in detail, but where appropriate, the techniques and equipment should be considered as part of the specification.

[0024] First, the optical transmission path in the near-infrared brain function imaging device in the present application is introduced. The optical transmission path in the near-infrared brain function imaging device in the present application is used to characterize the transmission path of the near-infrared light used when the near-infrared brain function imaging device is in the working state, which is specifically the components related to optical transmission of the near-infrared brain function imaging device in the whole machine state. It can be understood that the whole machine state of the near-infrared brain function imaging device means that the components related to optical transmission have been assembled or connected, and the device can directly enter the working state. For example, the head cap of the near-infrared brain function imaging device is worn on the head of the subject, and the device can enter the working state to collect the near-infrared signal of the subject's head after it is turned on. It can be understood that the components related to optical transmission may include at least one of a light source part, a transmitting probe, a receiving probe, a transmission cable (such as an optical fiber) between the transmitting probe and the light source part, a transmission cable between the receiving probe and the optical processing module, and a light receiving part; in some embodiments, the components related to optical transmission may also include a head-mounted device for installing a transmitting probe and / or a receiving probe, and the head-mounted device may be, for example, a head cap worn on the head of the subject for installing a transmitting probe and / or a receiving probe. The above-mentioned light transmission-related components can be arbitrarily combined and coordinated to form an optical transmission path for emitting near-infrared light to the brain and / or an optical transmission path for receiving near-infrared light from the brain. For example, some light source units are directly installed in the transmitting probe, and the near-infrared light emitted by them can directly enter the subject's head without being transmitted through optical fiber. In near-infrared brain function imaging devices used in scenarios such as nuclear magnetic resonance and transcranial magnetic resonance, the light source unit is arranged inside the main unit, and the near-infrared light emitted by the light source unit can be transmitted to the transmitting probe through an optical fiber cable and then enter the subject's head. For example, in some near-infrared brain function imaging devices, the near-infrared light from the subject can be transmitted to the optical processing module through optical fiber. In other near-infrared brain function imaging devices, the optical processing module can be integrated on a head cap, and the near-infrared light from the subject can be directly acquired by the optical processing module integrated on the head cap.

[0025] In summary, there is an optical transmission path in the near-infrared brain function imaging device that transmits near-infrared light to an object and / or transmits near-infrared light from an object, but the present application does not specifically limit the setting position of the optical transmission path, the design of specific components constituting the optical transmission path, the combination of each component, the matching method, etc.

[0026] Exemplarily, the schematic diagram of the optical transmission path in the near-infrared brain function imaging device can be as follows: Figure 1 As shown, Figure 1As shown, the near-infrared brain function imaging device includes a host, a transmission cable, a transmitting probe S and a receiving probe D respectively connected to each transmission cable, and the transmitting probe S and the receiving probe D are assembled on a head cap, wherein the host includes a light source unit and a light processing module, and when the near-infrared brain function imaging device is used in a complete state, the near-infrared light emitted by the light source unit enters the transmitting probe S on the head cap via the transmission cable, and is emitted from the transmitting probe S to enter the subject's head, and the near-infrared light from the subject's head is acquired by the receiving probe D on the head cap, and reaches the light processing module via the transmission cable, and the light processing module processes and analyzes the near-infrared light signal and transmits it to the processor or display, at which time the light transmission path in the near-infrared brain function imaging device in the complete state includes the host, the optical fiber cable, the transmitting probe S, the receiving probe D, and the head cap for installing the probe. This is only used as an example and does not constitute a limitation on the present application scheme.

[0027] Figure 2 A flow chart of a method for detecting an optical transmission path in a near-infrared brain function imaging device according to an embodiment of the present application is shown. In the flow chart, the arrows from step S201 to step S204 shown in the figure are merely examples of the execution order, not limitations. The technical solution of the present application is not limited to the execution order described in the embodiments, and the steps in the execution order can be combined, decomposed, or the order can be changed, as long as the logical relationship of the execution content is not affected.

[0028] Among them, the near-infrared brain function imaging device may include a light source part, a transmitting probe, a receiving probe and a light processing module. The light processing module may include a photoelectric conversion unit for converting an optical signal into an electrical signal. For example, the photoelectric conversion unit can convert the optical signal into a light intensity voltage value for characterizing the light intensity.

[0029] In this embodiment, there is an optical transmission path in the near-infrared brain function imaging device for transmitting near-infrared light to the object and / or transmitting near-infrared light from the object. Taking the use of the near-infrared brain function imaging device to detect the brain of the object as an example, for example, the near-infrared brain function imaging device may also include a head cap, which is used to be worn on the head of the object, and the head cap may have multiple probes for transmitting near-infrared light and / or receiving near-infrared light. Each of the multiple probes can be configured as a transmitting probe or a receiving probe, and each pair of probes arranged in pairs can form a detection channel. In some embodiments, the near-infrared light emitted by the light source part can be transmitted to the transmitting probe through a transmission cable, and the transmitting probe emits near-infrared light to the head of the object. The receiving probe on the head cap receives the near-infrared light scattered from the head, and transmits the received near-infrared light to the light processing module through the transmission cable.

[0030] The light source unit and the transmitting probe may be provided separately or integrated into one body. Similarly, the receiving probe and the optical processing module may be provided separately or integrated into one body. There is no specific limitation on this.

[0031] The performance of the optical transmission path of near-infrared brain function imaging equipment will directly affect the detection effect of brain detection. The attenuation of light in the brain environment can be simulated by measuring the phantom to detect the performance of the optical transmission path in the near-infrared imaging equipment. Figure 3 As shown, the near-infrared brain function imaging device 400 includes at least one probe group, which is composed of a transmitting probe (S) and a receiving probe (D). Figure 3 4 probe groups are shown in the figure, namely S1D1, S2D2, S3D3, and S4D4. The measurement phantom 300 is provided with a first hole 301 for installing a transmitting probe (S), and a second hole 302 for installing a receiving probe (D). For example, the transmitting probes S1, S2, S3, and S4 are respectively installed on each first hole 301, and the receiving probes D1, D2, D3, and D4 are respectively installed on each second hole 302. The measurement phantom 300 and the near-infrared brain function imaging device 400 can be connected by wire or wirelessly, so that the near-infrared brain function imaging device 400 can directly obtain relevant information of the measurement phantom 300, and collect and analyze the light intensity data of the output light emitted from the measurement phantom 300.

[0032] In step S201, light attenuation intensity calibration data of a measurement phantom is obtained, wherein the measurement phantom is used to simulate the attenuation of incident light in an object. The light attenuation intensity calibration data can be pre-stored in a storage device of the measurement phantom, and the storage device can be a USB flash drive physically restricted to read-only, or other types of storage devices, which are not limited to this. The storage device can also store other device information of the measurement phantom. After the near-infrared brain function imaging device is connected to the measurement phantom, the near-infrared brain function imaging device can directly read the relevant device information stored in the storage device to directly obtain the light attenuation intensity calibration data of the measurement phantom.

[0033] Specifically, Figure 3 The near-infrared brain functional imaging device 400 can provide an interactive interface for interacting with the user. For example, a data acquisition item 303 is provided on the interactive interface so that the user can trigger the data acquisition item 303 to perform an acquisition operation of acquiring light attenuation intensity calibration data.

[0034] In some other embodiments, when the light attenuation intensity calibration data of the measurement phantom is obtained, first prompt information for prompting that the light attenuation intensity calibration data has been obtained is provided, such as Figure 4As shown, the first prompt information is detection completion. At this time, the user can confirm that the light attenuation intensity calibration data of the measurement phantom has been obtained based on the first prompt information. In addition, the first prompt information can also be acquisition completion or light attenuation intensity calibration data has been obtained, which is not specifically limited as long as it can be used to prompt the user that the light attenuation intensity calibration data has been obtained.

[0035] In the case where the light attenuation intensity calibration data of the measurement phantom cannot be obtained, a second prompt information is provided to prompt the user to re-acquire the light attenuation intensity calibration data of the measurement phantom. For example, the second prompt information is a detection failure. At this time, the user can know based on the second prompt information that the light attenuation intensity calibration data has not been obtained, and it is necessary to check the measurement phantom and related components such as the near-infrared brain function imaging device. In addition, the second prompt information can also be acquisition failure, please re-acquire or please update the measurement phantom, which is not specifically limited. Based on the second prompt information, the user can check the connection between the measurement phantom and the near-infrared brain function imaging device, and re-acquire the light attenuation intensity calibration data until the first prompt information is displayed to enter the next step.

[0036] In some other embodiments, the light attenuation intensity calibration data includes at least one of the light attenuation intensity deviation of the measurement phantom relative to the standard phantom and the light attenuation intensity corresponding to the measurement phantom. The light attenuation intensity deviation can be the difference between the light attenuation intensity corresponding to the measurement phantom and the preset attenuation intensity. Specifically, the transmitting probe and the receiving probe in the same probe group in the near-infrared brain functional imaging device can be used to obtain the standard attenuation light intensity value of the incident light emitted after entering the standard phantom for standard light attenuation, and the measured attenuation light intensity value of the incident light emitted after entering the measurement phantom for measured light attenuation, and then the light attenuation intensity deviation is calculated according to formula (1), wherein formula (1): ΔdB=10log 10 (I1 / I2), where ΔdB represents the light attenuation intensity deviation, I1 represents the measured attenuation light intensity value, and I2 represents the standard attenuation light intensity value.

[0037] The standard phantom has a preset attenuation intensity for the standard light attenuation of the incident light, for example, the preset attenuation intensity is 60 dB. Based on the light attenuation intensity deviation and the preset attenuation intensity, the light attenuation intensity corresponding to the measured phantom is obtained, for example, if the preset attenuation intensity is 60 dB and the deviation of the light attenuation intensity of the measured phantom relative to the standard phantom is 3 dB, then the light attenuation intensity corresponding to the measured phantom is 57 dB.

[0038] That is to say, the light attenuation intensity calibration data can be used to calibrate the light attenuation intensity of the outgoing light emitted from the measurement phantom, so as to eliminate the problem of deviation in the light attenuation intensity of the outgoing light emitted from the measurement phantom due to differences in the light attenuation intensity of the incident light entering the interior of the measurement phantom caused by individual differences in the measurement phantom.

[0039] In some other embodiments of the present application, before the incident light enters the measurement phantom detection environment, the detection mode corresponding to the current detection is determined, wherein the detection mode is used to characterize the properties of the probe group to be detected, and the probe group is composed of a transmitting probe and a receiving probe. The properties of the probe group can be understood as the number of probe groups, and the detection mode can include a single detection mode and a multi-round detection mode. In the case where the number of probe groups to be detected is less than or equal to the maximum hole position provided by the measurement phantom, the detection mode can be a single detection mode; in the case where the number of probe groups to be detected is greater than the maximum hole position provided by the measurement phantom, the detection mode can be a multi-round detection mode.

[0040] For example, when only one probe group needs to be detected, the detection mode corresponding to the current detection is the single detection mode. Alternatively, when five probe groups need to be detected and the measurement phantom can provide a maximum of 10 probe group holes each time, the detection mode corresponding to the current detection is the single detection mode.

[0041] For example, when 15 probe groups need to be tested and the measurement phantom can provide hole positions of a maximum of 10 probe groups at a time, the detection mode corresponding to the current detection is the multi-round detection mode.

[0042] This is only an exemplary description and does not constitute a specific limitation on the detection mode.

[0043] In this embodiment, a first probe hole position diagram matching the detection mode is displayed to indicate that the transmitting probe and the receiving probe are installed at corresponding positions of the measurement phantom according to the first probe hole position diagram. Specifically, Figure 5 A first probe hole position diagram is shown, in which the hole positions for installing the transmitting probe and the hole positions for installing the receiving probe are distinguished and displayed using symbols that can be clearly distinguished. For example, hole position symbols such as A11, A21, A31, A12, A22 are used to represent the positions of each hole position for installing the transmitting probe, and hole position symbols such as B11, B21, B31, B12, B22 are used to represent the positions of each hole position for installing the receiving probe. The first probe hole position diagram only shows some hole position symbols, and does not show other hole position symbols.

[0044] When it is necessary to detect the four probe groups S1D1, S5D5, S2D2 and S6D6, the detection mode is a single detection mode, and a first probe hole position map matching the single detection mode is displayed accordingly. The first probe hole position map indicates that the transmitting probes S1, S5, S2 and S6 are respectively installed at the positions of the hole position symbols A11, A21, A12 and A22 of the measurement phantom, and the receiving probes D1, D5, D2 and D6 are respectively installed at the positions of the hole position symbols B11, B21, B12 and B22 of the measurement phantom.

[0045] This is only used as an example for explanation, and does not constitute a specific limitation on the first probe hole position map. The first probe hole position map can be arranged by the user, or recommended by the processor to the user, for example, the matching hole positions can be recommended based on the light attenuation intensity deviation of the measured phantom relative to the standard phantom, or the matching hole positions can be randomly selected, and there is no limitation on this.

[0046] In other embodiments, when the number of probe groups to be tested is greater than the upper limit of the number of probe groups to be tested in a single time corresponding to the measurement phantom, a detection scheme including multiple detections may be determined. For example, when the number of probe groups to be tested is 15 and the upper limit of the number of probe groups to be tested in a single time corresponding to the measurement phantom is 12, in this case, only a single detection cannot detect all the probe groups, and two detections are required.

[0047] In each test, a second probe hole position map matching the current test is displayed to indicate that the transmitting probe and the receiving probe are installed to the corresponding positions of the measurement phantom according to the second probe hole position map. For example, in the case where two tests are required, the corresponding second probe hole position map is matched for each test. When performing the first test, the user installs the transmitting probe and the receiving probe to be tested in the near-infrared brain functional imaging device to the corresponding hole positions according to the displayed second probe hole position map for the first test. After the test is completed, the user can install the transmitting probe and the receiving probe to be tested to the corresponding hole positions according to the displayed second probe hole position map matching the second test for the second test.

[0048] In step S202, the initial light intensity detection result of the outgoing light emitted from the measurement phantom after the incident light enters the measurement phantom detection environment is obtained. Figure 3 After the transmitting probes S1, S2, S3, and S4 are respectively installed on the first hole positions 301, and the receiving probes D1, D2, D3, and D4 are respectively installed on the second hole positions 302, and the near-infrared brain function imaging device 400 is connected to the measurement phantom 300, the near-infrared brain function imaging device 400 can directly obtain the light attenuation intensity calibration data stored in the storage device in the measurement phantom 300.

[0049] In some other embodiments of the present application, programs related to data analysis can be stored in a storage device of the measurement phantom 300. When in use, the program can be first obtained from the measurement phantom 300, and then the program can be used to perform data analysis; in addition, programs related to data analysis can also be directly deployed on the computer device of the near-infrared brain functional imaging device 400, which is not limited to the embodiments of the present disclosure.

[0050] like Figure 6 , click on the Start Collection item 601 in the collection interface on the near-infrared brain function imaging device (after clicking, the "Start Collection Item 601" becomes the "Stop Collection Item"), and the near-infrared brain function imaging device transmits near-infrared light to the transmitting probe through the transmission cable, and the transmitting probe emits near-infrared light to the measurement phantom. The near-infrared light entering the detection environment of the measurement phantom undergoes light attenuation, and the near-infrared light emitted from the measurement phantom is received by the receiving probe and transmitted to the light processing module through the transmission cable to obtain the initial light intensity detection result, and the initial light intensity detection result is analyzed and processed. If there is an abnormal waveform during the collection process, the user can pause the collection by clicking on the Stop Collection item (not shown), check whether the transmitting probe and the receiving probe are loose or have other problems, or click on the previous step 602 to check whether the previous settings are correct. After troubleshooting the problem, click on the Start Collection item 601 again to restart the collection. Before the collection is completed, the next step 603 is in an unselectable state, and becomes an selectable state after the collection is completed, so that the user can perform the next operation by clicking on the next step 603.

[0051] This is only an exemplary description and does not constitute a specific limitation on the specific solution.

[0052] In step S203, based on the initial light intensity detection result and the light attenuation intensity calibration data of the measurement phantom, the standard light intensity detection result of the optical transmission path in the standard phantom detection environment is determined. In this way, the initial light intensity detection result of the optical transmission path in the measurement phantom detection environment can be converted into a standard light intensity detection result in the standard phantom detection environment to eliminate the influence of individual differences in the measurement phantom.

[0053] Specifically, the standard light intensity detection result can be calculated according to formula (2), which is as follows: ,in, I 标 Indicates the standard light intensity detection result. I 初 represents the initial light intensity detection result, OLIndicates the light attenuation intensity corresponding to the measured phantom. Wherein, the light attenuation intensity corresponding to the measured phantom can be obtained based on the light attenuation intensity calibration data. In some other embodiments, the initial light intensity detection result and the standard light intensity detection result include a light intensity voltage value obtained by the photoelectric conversion unit for characterizing the light intensity.

[0054] In step S204, the standard light intensity detection result is compared with the standard light intensity range to determine the detection result of the optical transmission path in the near-infrared brain function imaging device. Among them, the standard light intensity range can be an empirical value measured based on a newly manufactured near-infrared brain function imaging device, and there is no specific limitation on this. Specifically, if the standard light intensity detection result exceeds the standard light intensity range, it means that there is an abnormality in the optical transmission path in the near-infrared brain function imaging device, and it is necessary to check the light source part, optical fiber, probe, host and other components. If the standard light intensity detection result is within the standard light intensity range, it means that the performance of the optical transmission path meets the use requirements.

[0055] In some embodiments, based on the method for detecting the optical transmission path in the near-infrared brain function imaging device provided in this embodiment, the whole near-infrared brain function imaging device to be shipped can also be detected, or the performance of the optical transmission path of the near-infrared brain function imaging device in use can be regularly detected. Moreover, by converting the initial light intensity detection result of the optical transmission path in the measurement phantom detection environment into the standard light intensity detection result in the standard phantom detection environment, the adverse effect of the individual differences of the measurement phantom on the performance of the optical transmission path of the near-infrared brain function imaging device can be eliminated. Based on the comparison of the standard light intensity detection result with the standard light intensity range, the detection result of the optical transmission path in the near-infrared brain function imaging device is determined, which realizes the standardized detection of the performance of the optical transmission path of the near-infrared brain function imaging device, and improves the accuracy and reliability of the detection result of the optical transmission path in the near-infrared brain function imaging device.

[0056] In some embodiments of the present application, the transmitting probe transmits near-infrared light of at least two wavelengths to the measurement phantom, and the receiving probe transmits the near-infrared light from the measurement phantom. For example, the wavelength of the near-infrared light may include 730nm, 808nm, 850nm, or other wavelengths, which are not specifically limited. Figure 7 As shown, at least two optional wavelength selection items 701 are displayed on the display interface. For example, when the wavelength selection item 701 with a wavelength of 730 nm is selected, the light intensity voltage value of the near-infrared light with a target wavelength of 730 nm after light attenuation in the standard phantom detection environment is displayed on the display interface. The unit of the light intensity voltage value may be mV or other voltage-related units, which are not specifically limited.

[0057] In some embodiments of the present application, the near-infrared brain function imaging device includes a plurality of probe groups, wherein the probe groups are composed of a transmitting probe and a receiving probe, wherein the transmitting probe transmits near-infrared light of at least two wavelengths to the measurement phantom, and the receiving probe transmits near-infrared light from the measurement phantom; a detection result page can be displayed according to the detection result of the optical transmission path in the near-infrared brain function imaging device, and the detection result page is as follows: Figure 7 The detection result page includes at least two wavelength selection items 701, range prompt information corresponding to the standard light intensity range, and light intensity voltage values ​​corresponding to multiple probe groups; the light intensity voltage value corresponding to each probe group includes the light intensity voltage value corresponding to the near-infrared light of the target wavelength from the measurement phantom transmitted by the receiving probe when the wavelength of the incident light is the target wavelength.

[0058] Specifically, Figure 7 , the range prompt information corresponding to the standard light intensity range can be a range indicated by a dotted line. For example, the lower limit is 145, the upper limit is 198, and both the lower limit area and the upper limit area are indicated by dotted lines to indicate that the standard light intensity range is 145-198. Figure 7 In the figure, the light intensity voltage values ​​corresponding to each probe group are shown, so as to make a horizontal comparison of the light intensity voltage values ​​of different probe groups. On the display interface, the light intensity voltage values ​​corresponding to multiple probe groups under the default wavelength can be displayed. For example, if the default wavelength is 730nm, then after entering the display interface of the light intensity voltage value, the light intensity voltage values ​​corresponding to multiple probe groups under the wavelength of 730nm are displayed. After selecting the wavelength selection item 701 of 808nm wavelength, it switches to display the light intensity voltage values ​​corresponding to multiple probe groups under the wavelength of 808nm. Figure 7 In the display, the light intensity voltage values ​​corresponding to multiple probe groups are displayed simultaneously, which is helpful for users to quickly and accurately observe the optical transmission paths with abnormalities and to make horizontal comparisons on the performance of various optical transmission paths.

[0059] Figure 7 This is only an example of an implementation method, and does not constitute a limitation on the specific solution. For example, the display interface may only display the light intensity voltage value of the probe group corresponding to the optical transmission path with an abnormality, or may not display the standard light intensity voltage range but only display the light intensity voltage value corresponding to each probe group.

[0060] For example, when the wavelength of the incident light is the target wavelength, the light intensity voltage value corresponding to the near-infrared light from the measurement phantom transmitted by the receiving probe of each probe group is displayed, and the light intensity voltage value exceeding the standard light intensity voltage range is highlighted. Figure 7As shown, the light intensity voltage value corresponding to each probe group is marked with a dot symbol. Assuming that the target wavelength is 808nm, when the wavelength of the incident light is 808nm, the light intensity voltage value corresponding to probe group S1D1 is 150, and the light intensity voltage value corresponding to probe group S2D2 is 138 on the display interface. Other probe groups are not listed one by one. Among them, when the standard light intensity voltage range is 145-198, the light intensity voltage value 138 corresponding to probe group S2D2 exceeds the standard light intensity voltage range, then the symbol of the light intensity voltage value 138 corresponding to probe group S2D2 is displayed as a white dot, and other symbols within the standard light intensity voltage range are all black dots. In this way, it is helpful for users to quickly observe the probe group S2D2 corresponding to the abnormal optical transmission path, and then check and adjust the optical transmission path where the probe group S2D2 is located.

[0061] In addition, after the user has observed the light intensity voltage values ​​corresponding to each probe group when the target wavelength is 808nm, if the user wants to continue to observe the light intensity voltage values ​​corresponding to each probe group when the target wavelength is 850nm, the target wavelength can be updated by selecting the wavelength selection item 701 corresponding to 850nm. After the target wavelength is updated to 850nm, the light intensity voltage values ​​corresponding to each probe group when the wavelength of the incident light is 850nm are displayed, and the light intensity voltage values ​​exceeding the standard light intensity voltage range are continued to be highlighted. That is to say, in some other embodiments of the present application, the light intensity voltage values ​​corresponding to the near-infrared light transmitted by the receiving probe from the measuring phantom can be displayed in response to the update operation of the target wavelength, and the light intensity voltage values ​​exceeding the standard light intensity voltage range are highlighted.

[0062] In this embodiment, there is no limitation on the update operation of the target wavelength. For example, the target wavelength can be updated by selecting wavelength selection items corresponding to different wavelengths. Alternatively, when the symbols of the light intensity voltage values ​​corresponding to each probe group under multiple wavelengths are displayed simultaneously, the target wavelength can be updated by clicking on the symbols of the light intensity voltage values ​​corresponding to each probe group under the target wavelength that the user is concerned about, while the symbols of the light intensity voltage values ​​corresponding to each probe group under other wavelengths are grayed out.

[0063] In some embodiments of the present application, a device for detecting an optical transmission path in a near-infrared brain function imaging device is provided, wherein the near-infrared brain function imaging device has an optical transmission path for transmitting near-infrared light to an object and / or receiving and transmitting near-infrared light from an object; the device includes a processing unit, and the processing unit is configured to: obtain light attenuation intensity calibration data of a measurement phantom, wherein the measurement phantom is used to simulate the attenuation of incident light in an object; obtain the initial light intensity detection result of the outgoing light emitted from the measurement phantom after the incident light enters the measurement phantom detection environment; determine the standard light intensity detection result of the optical transmission path in a standard phantom detection environment based on the initial light intensity detection result and the light attenuation intensity calibration data of the measurement phantom; compare the standard light intensity detection result with the standard light intensity range to determine the detection result of the optical transmission path in the near-infrared brain function imaging device. In this way, it is possible to avoid the inability to accurately detect the performance of the optical transmission path of the near-infrared brain function imaging device due to the differences of the measurement phantom itself, and it is possible to eliminate the adverse effects of the problems of the measurement phantom itself on the performance of the detection optical transmission path. By comparing the standard light intensity detection results obtained after conversion with the standard light intensity range, standardized detection of the optical transmission path of the near-infrared brain function imaging device is achieved, and the accuracy and credibility of the detection results of the performance detection of the optical transmission path of the near-infrared brain function imaging device are improved.

[0064] The processing unit may be a processor, and the processor may be a processing device including one or more general-purpose processing devices, such as a microprocessor, a central processing unit (CPU), etc. More specifically, the processor may be a complex instruction set computing (CISC) microprocessor, a reduced instruction set computing (RISC) microprocessor, a very long instruction word (VLIW) microprocessor, a processor running other instruction sets, or a processor running a combination of instruction sets. The processor may also be one or more special-purpose processing devices, such as an application-specific integrated circuit (ASIC), a field programmable gate array (FPGA), a digital signal processor (DSP), a system on a chip (SoC), etc. The processor may be included in a near-infrared brain function imaging device, or may be arranged outside the near-infrared brain function imaging device, and cooperate with the near-infrared brain function imaging device to perform relevant data analysis and processing, thereby forming a device for detecting the optical transmission path in the near-infrared brain function imaging device. The processing unit in the device is configured to execute the method described in each embodiment of the present application.

[0065] This application describes various operations or functions that may be implemented as software codes or instructions or defined as software codes or instructions. Such content may be source code or differential code ("incremental" or "patch" code) that can be directly executed ("object" or "executable" form). Software codes or instructions may be stored in a computer-readable storage medium, and when executed, may cause a machine to perform the described functions or operations, and include any mechanism for storing information in a form accessible to a machine (e.g., a computing device, an electronic system, etc.), such as recordable or non-recordable media (e.g., read-only memory (ROM), random access memory (RAM), magnetic disk storage media, optical storage media, flash memory devices, etc.).

[0066] The exemplary methods described in this application can be implemented at least in part by a machine or computer. In some embodiments, a computer-readable storage medium stores a computer program, and when executed by a processing device, the computer program performs the following steps: obtaining light attenuation intensity calibration data of a measurement phantom, wherein the measurement phantom is used to simulate the attenuation of incident light in an object; obtaining an initial light intensity detection result of the outgoing light emitted from the measurement phantom after the incident light enters the measurement phantom detection environment; determining a standard light intensity detection result of the optical transmission path in a standard phantom detection environment based on the initial light intensity detection result and the light attenuation intensity calibration data of the measurement phantom; comparing the standard light intensity detection result with a standard light intensity range to determine a detection result of the optical transmission path in the near-infrared brain function imaging device.

[0067] The methods for detecting the optical transmission path in the near-infrared brain function imaging device described in various embodiments of the present application can be combined here and will not be described in detail.

[0068] The implementation of such a method may include software code, such as microcode, assembly language code, high-level language code, etc. Various software programming techniques may be used to create various programs or program modules. For example, a program portion or program module may be designed with or by means of Java, Python, C, C++, assembly language, or any known programming language. One or more of such software portions or modules may be integrated into a computer system and / or a computer-readable medium. Such software code may include computer-readable instructions for executing various methods. The software code may form a part of a computer program product or a computer program module. In addition, in an example, the software code may be tangibly stored on one or more volatile, non-temporary or non-volatile tangible computer-readable media, such as during execution or at other times. Examples of these tangible computer-readable media may include, but are not limited to, hard disks, removable disks, removable optical disks (such as optical disks and digital video disks), cassettes, memory cards or memory sticks, random access memories (RAMs), read-only memories (ROMs), etc.

[0069] In addition, although exemplary embodiments have been described herein, the scope includes any and all embodiments based on the present application with equivalent elements, modifications, omissions, combinations (e.g., various embodiments intersecting schemes), adaptations or changes. The elements in the claims are to be interpreted broadly based on the language adopted in the claims, and are not limited to the examples described in this specification or during the practice of this application, and the examples are to be interpreted as non-exclusive. Therefore, this specification and examples are intended to be considered as examples only, and the true scope and spirit are indicated by the following claims and the full scope of their equivalents.

[0070] The above description is intended to be illustrative rather than restrictive. For example, the above examples (or one or more schemes thereof) may be used in combination with each other. For example, a person of ordinary skill in the art may use other embodiments when reading the above description. In addition, in the above-mentioned specific embodiments, various features may be grouped together to simplify the present application. This should not be interpreted as an intention that a disclosed feature that is not required to be protected is necessary for any claim. On the contrary, the subject matter of the present application may be less than all the features of a particular disclosed embodiment. Thus, the claims are incorporated herein as examples or embodiments in the specific embodiments, wherein each claim is independently a separate embodiment, and it is considered that these embodiments may be combined with each other in various combinations or arrangements. The scope of the present application should be determined with reference to the attached claims and the full scope of equivalent forms granted by these claims.

[0071] The above embodiments are only exemplary embodiments of the present application and are not intended to limit the present application. The protection scope of the present application is defined by the claims. Those skilled in the art may make various modifications or equivalent substitutions to the present application within the essence and protection scope of the present application, and such modifications or equivalent substitutions shall also be deemed to fall within the protection scope of the present application.

Claims

1. A method for detecting an optical transmission path in a near-infrared brain function imaging device, characterized in that: The near-infrared brain function imaging device has an optical transmission path for transmitting near-infrared light to the object and / or transmitting near-infrared light from the object, and the method comprises: Acquiring light attenuation intensity calibration data of a measurement phantom, wherein the measurement phantom is used to simulate the attenuation of incident light in an object; Acquiring an initial light intensity detection result of the outgoing light emitted from the measurement phantom after the incident light enters the measurement phantom detection environment; Determining a standard light intensity detection result of the optical transmission path under a standard phantom detection environment based on the initial light intensity detection result and the light attenuation intensity calibration data of the measurement phantom; The standard light intensity detection result is compared with the standard light intensity range to determine the detection result of the light transmission path in the near-infrared brain function imaging device.

2. The method according to claim 1, characterized in that The near-infrared brain function imaging device at least comprises: a light source unit, a transmitting probe, a receiving probe and a light processing module; The optical transmission path is distributed between the light source part and the transmitting probe, and / or between the receiving probe and the optical processing module.

3. The method according to claim 1 or 2, characterized in that: The light attenuation intensity calibration data includes at least one of the light attenuation intensity deviation of the measurement phantom relative to the standard phantom and the light attenuation intensity corresponding to the measurement phantom.

4. The method according to claim 2, characterized in that: The light processing module comprises a photoelectric conversion unit for converting a light signal into an electrical signal, and the initial light intensity detection result and the standard light intensity detection result comprise a light intensity voltage value obtained by the photoelectric conversion unit for characterizing light intensity.

5. The method according to claim 1 or 4, characterized in that: The near-infrared brain function imaging device comprises at least one probe group, the probe group is composed of a transmitting probe and a receiving probe, the transmitting probe transmits near-infrared light of at least two wavelengths to the measurement phantom, and the receiving probe transmits the near-infrared light from the measurement phantom; The method further comprises: The light intensity voltage value corresponding to the near-infrared light from the measurement phantom transmitted by the receiving probe of each probe group when the wavelength of the incident light is the target wavelength is displayed, and the light intensity voltage value exceeding the standard light intensity voltage range is highlighted.

6. The method according to claim 5, characterized in that The method also includes: in response to an update operation on the target wavelength, displaying the light intensity voltage value corresponding to the near-infrared light from the measurement phantom transmitted by the receiving probe of each probe group when the wavelength of the incident light is the updated target wavelength, and highlighting the light intensity voltage value that exceeds the standard light intensity voltage range.

7. The method according to claim 1 or 2, characterized in that: The method further comprises: When the light attenuation intensity calibration data of the measurement phantom is obtained, providing first prompt information for prompting that the light attenuation intensity calibration data has been obtained; In the case where the light attenuation intensity calibration data of the measurement phantom cannot be obtained, second prompt information is provided for prompting to re-acquire the light attenuation intensity calibration data of the measurement phantom.

8. The method according to claim 1 or 2, characterized in that: Before the incident light enters the measurement phantom detection environment, the method further includes: Determine a detection mode corresponding to the current detection; wherein the detection mode is used to characterize the properties of the probe group to be detected, and the probe group is composed of a transmitting probe and a receiving probe; A first probe hole position diagram matching the detection mode is displayed to instruct the transmitter probe and the receiver probe to be installed at corresponding positions of the measurement phantom according to the first probe hole position diagram.

9. The method according to claim 8, characterized in that The method further comprises: When the number of probe groups to be tested is greater than the upper limit of the number of probe groups to be tested in a single time corresponding to the measurement phantom, determining a test scheme including multiple tests; In each test, a second probe hole position map matching the current test is displayed to indicate that the transmitting probe and the receiving probe are installed at corresponding positions of the measurement phantom according to the second probe hole position map.

10. The method according to claim 1 or 4, characterized in that: The near-infrared brain function imaging device comprises a plurality of probe groups, wherein the probe groups are composed of a transmitting probe and a receiving probe, wherein the transmitting probe transmits near-infrared light of at least two wavelengths to the measurement phantom, and the receiving probe transmits the near-infrared light from the measurement phantom; The method further comprises: Displaying a detection result page according to the detection result of the light transmission path in the near-infrared brain function imaging device; Among them, the detection result page contains at least two wavelength selection items, range prompt information corresponding to the standard light intensity range, and light intensity voltage values ​​corresponding to multiple probe groups; the light intensity voltage value corresponding to each probe group includes the light intensity voltage value corresponding to the near-infrared light from the measurement phantom transmitted by the receiving probe when the wavelength of the incident light is the target wavelength.

11. A device for detecting an optical transmission path in a near-infrared brain function imaging device, using a method for detecting an optical transmission path in a near-infrared brain function imaging device as described in any one of claims 1 to 10.

12. A computer-readable storage medium, characterized in that: The computer-readable storage medium stores a computer program, and when the computer program is executed by the processing device, it performs a method for detecting an optical transmission path in a near-infrared brain function imaging device as described in any one of claims 1 to 10.

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