A kind of roxithromycin capsule production device and production process

Abstract

The invention provides a roxithromycin capsule production device and a production process, which relate to the technical field of drug production, and comprise a workbench, wherein a rotating frame is provided at the left position of the top of the workbench; a medicine filling tank is provided at the right position of the top of the workbench; a mounting frame is provided in the medicine filling tank; and three adjusting rods are provided on the mounting frame, which can drive the adjusting rod to rotate through the rotating cooperation of a rotating ring and a bearing sleeve, and the limiting sliding of a limiting shaft on a limiting groove, so that a mounting sleeve can be driven to drive the adjusting rod to rotate, thereby realizing the process of squeezing and discharging medicine powder from a cylindrical cavity of a metering seat by a filling head, and the medicine powder is pushed downward by the rotating filling head, so that the medicine powder is effectively prevented from adhering to the filling head and the metering seat, and good fluidity of the medicine powder is ensured, and the problem that the existing roxithromycin capsule production device has poor fluidity in the capsule filling process, is easy to adhere to the filling rod and the metering seat, and affects the accuracy of capsule filling is solved.

Description

Technical Field

[0001] The invention relates to the technical field of drug production, and in particular to a roxithromycin capsule production device and a production process. Background Art

[0002] Roxithromycin is a white or off-white, odorless, bitter, slightly hygroscopic crystalline powder. Roxithromycin is a commonly used antibacterial and anti-inflammatory drug with a wide range of uses and significant effects. The clinically used roxithromycin preparations are mainly capsules and tablets. In order to better meet the medication needs of clinical patients, the process of roxithromycin capsules should be continuously developed and studied.

[0003] For example, the patent with application number CN202010544781.6 discloses a system for preparing roxithromycin capsules, including a device support, a stirring support, a filler support, a screening mechanism, a shaking mechanism, a filler mechanism and a stirring mechanism, which can efficiently and quickly complete the screening, filling and stirring processes of raw materials and particles. A method for preparing roxithromycin capsules has high reliability and high production efficiency. The drying temperature is 60°C to prevent the influence of high temperature on the melting of particles. The addition of silicon dioxide, talc and magnesium stearate makes the fluidity of particles better. The addition of poloxamer and povidone K30 improves the solubility of roxithromycin. The addition of low-substituted hydroxypropyl methylcellulose makes the particles quickly disintegrate into fine powder, which is beneficial to the dissolution of the drug. Through the improvement of the preparation method, the solubility of roxithromycin capsules is improved, the product quality standards are improved, and the patient's medication is safer and more effective.

[0004] When the existing roxithromycin capsule production device is in use, the fluidity of the powder is poor during the capsule filling process, and the powder is easily adhered to the filling rod and the metering seat, which affects the accuracy of the capsule filling. In addition, during the process of filling the powder into the capsule shell, there is a certain gap between the metering seat and the filler holding seat, which causes the powder to be spilled and wasted. In addition, the filling seats above and below the capsule shell need to be wiped and cleaned separately, and the cleaning process is relatively troublesome and needs to be carried out step by step, resulting in poor production efficiency of the equipment. Summary of the invention

[0005] In view of this, the present invention provides a roxithromycin capsule production device, which can make the installation sleeve drive the adjustment rod to rotate through the rotational cooperation of the rotating ring and the bearing sleeve, and the limiting sliding of the limiting shaft on the limiting groove, so as to realize the process of squeezing and discharging the powder from the cylindrical cavity of the metering seat by the filling head, and the filling head rotates to push the medicine downward, so as to effectively avoid the powder from adhering to the filling head and the metering seat, and ensure the good fluidity of the powder.

[0006] The present invention provides the purpose and efficacy of a roxithromycin capsule production device and production process, specifically including: a workbench, a rotating frame is provided at the left position on the top of the workbench; a medicine filling tank is provided at the right position on the top of the workbench; an installation frame is provided inside the medicine filling tank; three adjusting rods are provided on the installation frame, and the three adjusting rods are distributed in a linear array; a blanking seat is provided on the medicine filling tank, and the blanking seat corresponds to the position of the adjusting rod; a limiting frame is provided on the top of the workbench, and the limiting frame is located behind the rotating frame; two sliding frames are provided on the limiting frame, and the two sliding frames are symmetrically distributed; a servo motor is fixedly installed on one side of the limiting frame; a fastening component is provided on the top of the workbench, and the fastening component is located in front of the rotating frame; a capsule discharging frame is provided on the top of the workbench, and the capsule discharging frame is located on the left side of the rotating frame.

[0007] In at least some embodiments, a top cover holding seat and a filler holding seat are provided on the outer peripheral surface of the rotating frame, and the top cover holding seat and the filler holding seat are distributed in a circular array, and the top cover holding seat is located above the filler holding seat. A first chamfer is provided on one side edge of the top of the filler holding seat.

[0008] In at least some embodiments, a rotating disk is rotatably installed inside the medicine filling tank. Four measuring seats are provided on the rotating disk, and the four measuring seats are distributed in a circular array, and the measuring seats correspond to the positions of the blanking seat and the adjusting rod. A communication groove is provided at the bottom of the medicine filling tank, and the blanking seat is slidably installed in the communication groove.

[0009] In at least some embodiments, the installation frame has a "C" - shaped structure. Three limiting round rods are provided at the bottom of the upper horizontal plate of the installation frame, and the three limiting round rods are vertically parallel. A first tension spring is sleeved on the limiting round rods. Three limiting shafts are provided on the vertical plates of the installation frame, and the limiting shafts correspond to the positions of the limiting round rods. Two air cylinders are fixedly installed on the top of the upper horizontal plate of the installation frame, and the two air cylinders are symmetrically distributed.

[0010] In at least some embodiments, a filling head is provided at the bottom end of the adjusting rod, an installation sleeve is provided at the top end of the adjusting rod, and the limiting round rod passes through the installation sleeve. A limiting groove is provided on the outer peripheral surface of the installation sleeve, and the limiting shaft is slidably connected with the limiting groove. A rotating ring is provided at the top end of the installation sleeve. A connecting frame is provided between the three adjusting rods;

[0011] The connecting frame is of a rectangular frame structure. Three limiting rings are provided on the lower long rectangular rod of the connecting frame, and the limiting rings are slidably sleeved on the adjusting rod. Three bearing sleeves are provided on the upper long rectangular rod of the connecting frame, and the installation sleeve is rotatably connected with the bearing sleeve through the rotating ring. The end of the telescopic rod of the air cylinder is connected to the upper long rectangular rod of the connecting frame, and the two ends of the first tension spring are respectively connected to the connecting frame and the installation frame.

[0012] In at least some embodiments, a second chamfer is provided on one edge of the bottom of the material discharge seat, and the second chamfer matches the first chamfer. A support plate is provided on one side of the material discharge seat, and two limit slide bars are slidably penetrated on the support plate, and the two limit slide bars are symmetrically distributed.

[0013] A fixing plate is provided between the top ends of the two limiting slide bars, and the fixing plate is connected to the medicine filling tank. A connecting circular plate is provided at the bottom end of the limiting slide bar. A second tension spring is mounted on the limiting slide bar, and the two ends of the second tension spring are respectively connected to the connecting circular plate and the support plate.

[0014] In at least some embodiments, a fixing seat is provided at the bottom of the limiting frame, and the fixing seat is connected to the workbench. The limiting frame is a rectangular through-cavity structure, and two guide grooves are provided on the inner wall of the through-cavity of the limiting frame.

[0015] In at least some embodiments, the sliding frame is in a "T"-shaped structure, and three connecting columns are provided on the inner sides of the horizontal plates of the two sliding frames, wiping cotton rollers are provided at the ends of the connecting columns, and the upper and lower wiping cotton rollers correspond to the top cover holding seat and the filling holding seat respectively, and guide plates are provided at the ends of the vertical plates of the sliding frame, and the guide plates are slidably connected to the limit frame through guide grooves, and tooth plates are provided on the inner sides of the two guide plates.

[0016] In at least some embodiments, the servo motor is provided with a rotating shaft, and the rotating shaft is rotatably connected to the limit frame through a bearing, and a gear is provided on the rotating shaft, and the gear is located between two guide plates, and the gear is meshingly connected with the gear plate.

[0017] The invention discloses a production process of a roxithromycin capsule production device, comprising the following steps:

[0018] 1) First, during the process of filling the capsule bottom shell in the filler holding seat, the roxithromycin powder in the medicine filling tank enters the cylindrical cavity of the metering seat;

[0019] 2) Two cylinders provide power to push the connecting frame downward, driving the three adjusting rods to adjust downward;

[0020] 3) Through the rotational cooperation between the rotating ring and the bearing sleeve, the limiting shaft slides on the limiting groove, so that the mounting sleeve drives the adjusting rod to rotate, and the filling head realizes the process of squeezing and discharging the powder from the cylindrical cavity of the metering seat;

[0021] 4) Then, the second chamfer cooperates with the first chamfer to push the material discharging seat to slide upward along the limit slide rod, and the rebound pulling effect of the second tension spring is used to make the material discharging seat fit closely with the filling holding seat, so that the medicine powder is fully filled into the capsule shell of the filling holding seat;

[0022] 5) In addition, the servo motor provides power to drive the rotating shaft to rotate, and the gears and the two toothed plates are meshed to drive the two guide plates and the sliding frame to slide along the guide groove;

[0023] 6) The wiping cotton rollers are driven by the upper and lower sliding frames to adjust toward each other, and the empty slots of the capsule shell of the top cover holding seat and the filler holding seat are wiped at the same time to prevent the powder from contaminating the outer wall of the capsule.

[0024] The present invention provides a roxithromycin capsule production device, which has the following beneficial effects:

[0025] According to the embodiments of the present invention, two cylinders provide power to push the connecting frame downward, which can drive the three adjusting rods to adjust downward. Through the rotational cooperation of the rotating ring and the bearing sleeve, and the limited sliding of the limiting shaft on the limiting groove, the installing sleeve can drive the adjusting rod to rotate, thereby realizing the process of squeezing and discharging the powder from the cylindrical cavity of the metering seat by the filling head. The filling head rotates to push the medicine downward, which effectively prevents the powder from sticking to the filling head and the metering seat, thereby ensuring good fluidity of the powder.

[0026] In addition, the upper and lower parts of the material discharge seat respectively correspond to the metering seat and the filling holding seat. Through the cooperation of the second chamfer and the first chamfer, the material discharge seat can be pushed to slide upward along the limit slide rod for adjustment, and the rebound pulling effect of the second tension spring can be used to make the material discharge seat and the filling holding seat fit tightly, ensuring that the medicine powder is fully filled into the capsule shell of the filling holding seat. The metering seat and the filling holding seat are smoothly connected through the material discharge seat, which effectively avoids the spillage and waste of medicine, and the structure is more reasonable.

[0027] In addition, the servo motor provides power to drive the rotating shaft to rotate, and the gears and two toothed plates are engaged to drive the two guide plates and the sliding frame to slide along the guide groove at the same time. The upper and lower sliding frames drive the wiping cotton rollers to adjust toward each other, so that the empty grooves of the capsule shells of the top cover holding seat and the filler holding seat can be wiped at the same time to prevent the powder from contaminating the outer wall of the capsule. The upper and lower capsule shells can be wiped at one time by combining them in linkage, which simplifies the overall use process of the equipment and makes it convenient and flexible to operate. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] In order to more clearly illustrate the technical solution of the embodiment of the present invention, the drawings of the embodiment are briefly introduced below.

[0029] The drawings described below are only related to some embodiments of the present invention, but are not intended to limit the present invention.

[0030] In the attached picture:

[0031] Figure 1 is a schematic diagram of the overall axial viewing angle structure of an embodiment of the present invention;

[0032] Figure 2 is a schematic diagram of the structure of a rotating disk, a mounting frame and an adjusting rod according to an embodiment of the present invention;

[0033] Figure 3 is a schematic diagram of the structure of a mounting frame according to an embodiment of the present invention;

[0034] Figure 4 2 is a schematic diagram of the structure of the regulating rod in the explosion state of an embodiment of the present invention;

[0035] Figure 5 It is a schematic diagram of the explosion state structure of a part of the medicine filling tank, the material discharge seat and the filler containing seat of the embodiment of the present invention;

[0036] Figure 6 2 is a schematic diagram of the structure of a material discharging seat according to an embodiment of the present invention;

[0037] Figure 7 Schematic diagram of the structure of the limit frame, the sliding frame and the servo motor of an embodiment of the present invention;

[0038] Figure 8 It is a schematic diagram of the cross-sectional view structure of the limiting frame of an embodiment of the present invention.

[0039] Reference numerals list

[0040] 1. Workbench;

[0041] 2. Rotating frame; 201. Top cover receiving seat; 202. Filler receiving seat; 203. First chamfer;

[0042] 3. Medicine filling tank; 301. Rotating disk; 302. Measuring seat; 303. Connecting groove;

[0043] 4. Mounting frame; 401. Position-limiting round rod; 402. First tension spring; 403. Position-limiting shaft; 404. Cylinder;

[0044] 5. Adjusting rod; 501. Filling head; 502. Mounting sleeve; 503. Limiting groove; 504. Rotating ring; 505. Connecting frame; 5051. Limiting ring; 5052. Bearing sleeve;

[0045] 6. Material unloading seat; 601. Second chamfer; 602. Support plate; 603. Limiting slide bar; 6031. Fixed plate; 6032. Connecting circular plate; 6033. Second tension spring;

[0046] 7. Limiting frame; 701. Fixed seat; 702. Guide groove;

[0047] 8. Sliding frame; 801. Connecting column; 802. Wiping cotton roller; 803. Guide plate; 804. Tooth plate;

[0048] 9. Servo motor; 901. Rotating shaft rod; 902. Gear;

[0049] 10. Clamping component;

[0050] 11. Capsule discharging rack. Detailed implementation manners

[0051] In order to make the objectives, solutions and advantages of the technical solutions of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings of the specific embodiments of the present invention. Unless otherwise specified, the terms used herein have the ordinary meanings in the art. The same reference numerals in the drawings represent the same components.

[0052] Embodiment 1: Please refer to Figures 1 to 8 as shown in

[0053] The present invention provides a roxithromycin capsule production device and production process, including: a workbench 1, a rotating frame 2 is provided at the left side position of the top of the workbench 1; a medicament filling tank 3 is provided at the right side position of the top of the workbench 1; an installation frame 4 is provided inside the medicament filling tank 3; three adjusting rods 5 are provided on the installation frame 4, and the three adjusting rods 5 are distributed in a linear array; a blanking seat 6 is provided on the medicament filling tank 3, and the blanking seat 6 corresponds to the position of the adjusting rod 5; a limiting frame 7 is provided on the top of the workbench 1, and the limiting frame 7 is located behind the rotating frame 2; two sliding frames 8 are provided on the limiting frame 7, and the two sliding frames 8 are symmetrically distributed; a servo motor 9 is fixedly installed on one side of the limiting frame 7; a clamping component 10 is provided on the top of the workbench 1, and the clamping component 10 is located in front of the rotating frame 2; a capsule discharging rack 11 is provided on the top of the workbench 1, and the capsule discharging rack 11 is located on the left side of the rotating frame 2.

[0054] In the embodiment of the present disclosure, as Figures 2 to 4 shown, a rotating disk 301 is rotatably installed inside the medicament filling tank 3, four metering seats 302 are provided on the rotating disk 301, and the four metering seats 302 are distributed in a circular array, and the metering seats 302 correspond to the positions of the blanking seat 6 and the adjusting rod 5. A communication groove 303 is provided at the bottom of the medicament filling tank 3, and the blanking seat 6 is slidably installed in the communication groove 303;

[0055] The installation frame 4 has a "C" - shaped structure, and three limiting round rods 401 are provided at the bottom of the upper horizontal plate of the installation frame 4, and the three limiting round rods 401 are vertically parallelly distributed. A first tension spring 402 is sleeved on the limiting round rods 401. Three limiting shafts 403 are provided on the vertical plates of the installation frame 4, and the limiting shafts 403 correspond to the positions of the limiting round rods 401. Two air cylinders 404 are fixedly installed on the top of the upper horizontal plate of the installation frame 4, and the two air cylinders 404 are symmetrically distributed;

[0056] A filling head 501 is provided at the bottom end of the adjusting rod 5, a mounting sleeve 502 is provided at the top end of the adjusting rod 5, and the limiting round rod 401 penetrates the mounting sleeve 502, a limiting groove 503 is provided on the outer circumference of the mounting sleeve 502, and the limiting shaft 403 is slidably connected with the limiting groove 503, a rotating ring 504 is provided at the top end of the mounting sleeve 502, and a connecting frame 505 is provided between the three adjusting rods 5;

[0057] The connecting frame 505 is a rectangular frame structure, and three limit rings 5051 are provided on the long moment rod below the connecting frame 505, and the limit rings 5051 are slidably mounted on the adjusting rod 5, and three bearing sleeves 5052 are provided on the long moment rod above the connecting frame 505, and the mounting sleeve 502 is rotatably connected to the bearing sleeve 5052 through the rotating ring 504, and the telescopic rod end of the cylinder 404 is connected to the long moment rod above the connecting frame 505, and the two ends of the first tension spring 402 are respectively connected to the connecting frame 505 and the mounting frame 4, During the process of filling the capsule bottom shell in the material holding seat 202, the roxithromycin powder in the medicine filling tank 3 enters the cylindrical cavity of the metering seat 302, and then the two cylinders 404 provide power to push the connecting frame 505 downward, which can drive the three adjusting rods 5 to adjust downward. Through the rotation cooperation of the rotating ring 504 and the bearing sleeve 5052, and the limited sliding of the limiting shaft 403 on the limiting groove 503, the mounting sleeve 502 can drive the adjusting rod 5 to rotate, thereby realizing the process of squeezing and discharging the powder from the cylindrical cavity of the metering seat 302 by the filling head 501.

[0058] In the present disclosure, Figure 5 and Figure 6 As shown, a top cover receiving seat 201 and a filler receiving seat 202 are provided on the outer circumference of the rotating frame 2, and the top cover receiving seat 201 and the filler receiving seat 202 are distributed in a circular array, and the top cover receiving seat 201 is located above the filler receiving seat 202, and a first chamfer 203 is provided on one side edge of the top of the filler receiving seat 202;

[0059] A second chamfer 601 is provided on one edge of the bottom of the material discharging seat 6, and the second chamfer 601 matches the first chamfer 203. A support plate 602 is provided on one side of the material discharging seat 6, and two limit slide bars 603 are slidably penetrated on the support plate 602, and the two limit slide bars 603 are symmetrically distributed;

[0060] A fixing plate 6031 is provided between the top ends of the two limiting slide bars 603, and the fixing plate 6031 is connected to the medicine filling tank 3, and a connecting circular plate 6032 is provided at the bottom end of the limiting slide bar 603, and a second tension spring 6033 is mounted on the limiting slide bar 603, and the two ends of the second tension spring 6033 are respectively connected to the connecting circular plate 6032 and the support plate 602. In the above-mentioned process of filling the capsule bottom shell in the filling seat 202, the upper and lower parts of the discharge seat 6 correspond to the metering seat 302 and the filling seat 202 respectively, and the second chamfer 601 and the first chamfer 203 cooperate with each other to push the discharge seat 6 to slide upward along the limiting slide bar 603 for adjustment, and the rebound pulling effect of the second tension spring 6033 can make the discharge seat 6 fit closely with the filling seat 202, so as to ensure that the medicine powder is fully filled into the capsule shell of the filling seat 202.

[0061] Embodiment 2, based on embodiment 1, as Figure 7 and Figure 8 As shown, a fixing seat 701 is provided at the bottom of the limiting frame 7, and the fixing seat 701 is connected to the workbench 1, the limiting frame 7 is a rectangular through-cavity structure, and two guide grooves 702 are provided on the inner wall of the through-cavity of the limiting frame 7;

[0062] The sliding frame 8 is in a "T"-shaped structure, and three connecting columns 801 are provided on the inner sides of the two horizontal plates of the sliding frame 8. Wiping cotton rollers 802 are provided at the ends of the connecting columns 801, and the upper and lower wiping cotton rollers 802 correspond to the top cover receiving seat 201 and the filler receiving seat 202 respectively. A guide plate 803 is provided at the end of the vertical plate of the sliding frame 8, and the guide plate 803 is slidably connected to the limit frame 7 through the guide groove 702. Tooth plates 804 are provided on the inner sides of the two guide plates 803.

[0063] A rotating shaft 901 is provided on the servo motor 9, and the rotating shaft 901 is rotatably connected to the limit frame 7 through a bearing, and a gear 902 is provided on the rotating shaft 901, and the gear 902 is located between the two guide plates 803, and the gear 902 is meshingly connected with the tooth plate 804, wherein the servo motor 9 provides power to drive the rotating shaft 901 to rotate, and the meshing transmission of the gear 902 and the two tooth plates 804 can simultaneously drive the two guide plates 803 and the sliding frame 8 to slide along the guide groove 702, and the wiping cotton roller 802 is driven by the upper and lower sliding frames 8 to adjust toward each other, so that the empty grooves of the capsule shell of the top cover holding seat 201 and the filling holding seat 202 can be wiped at the same time to prevent the powder from contaminating the outer wall of the capsule.

[0064] The specific usage and function of this embodiment are as follows: first, in the process of filling the capsule bottom shell in the filling holding seat 202, the roxithromycin powder in the medicine filling tank 3 enters the cylindrical cavity of the metering seat 302, and then the two cylinders 404 provide power to push the connecting frame 505 downward, which can drive the three adjusting rods 5 to adjust downward, and the rotating ring 504 and the bearing sleeve 5052 rotate and cooperate, and the limiting shaft 403 limits the sliding of the limiting groove 503, so that the mounting sleeve 502 can drive the adjusting rod 5 to rotate, thereby realizing the process of squeezing and unloading the powder from the cylindrical cavity of the metering seat 302 by the filling head 501; wherein the unloading seat 6 corresponds to the metering seat 302 and the filling holding seat 202 respectively, through the second chamfer 601 and the first The chamfers 203 cooperate with each other to push the unloading seat 6 to slide upward along the limiting slide bar 603, and use the rebound pulling effect of the second tension spring 6033 to make the unloading seat 6 fit tightly with the filling holding seat 202, ensuring that the medicine powder is fully filled into the capsule shell of the filling holding seat 202; the servo motor 9 provides power to drive the rotating shaft 901 to rotate, and the gear 902 and the two toothed plates 804 are engaged and driven to drive the two guide plates 803 and the sliding frame 8 to slide along the guide groove 702 at the same time, and the upper and lower sliding frames 8 drive the wiping cotton roller 802 to adjust toward each other, so as to wipe the empty grooves of the capsule shell of the top cover holding seat 201 and the filling holding seat 202 at the same time, so as to prevent the medicine powder from contaminating the outer wall of the capsule.

[0065] The above description is merely an exemplary embodiment of the present invention and is not intended to limit the protection scope of the present invention. The protection scope of the present invention is determined by the appended claims.

Claims

1. A roxithromycin capsule production device, characterized in that: It includes a workbench, and a rotating frame is provided at the left position on the top of the workbench; a medicine filling tank is provided at the right position on the top of the workbench; an installation frame is provided inside the medicine filling tank; three adjusting rods are provided on the installation frame, and the three adjusting rods are distributed in a linear array; a blanking seat is provided on the medicine filling tank, and the blanking seat corresponds to the position of the adjusting rod; a limiting frame is provided on the top of the workbench, and the limiting frame is located behind the rotating frame; two sliding frames are provided on the limiting frame, and the two sliding frames are distributed symmetrically; a servo motor is fixedly installed on one side of the limiting frame; a buckling assembly is provided on the top of the workbench, and the buckling assembly is located in front of the rotating frame; a capsule discharging frame is provided on the top of the workbench, and the capsule discharging frame is located on the left side of the rotating frame. A top cover holding seat and a filler holding seat are provided on the outer peripheral surface of the rotating frame, and the top cover holding seat and the filler holding seat are distributed in an annular array, and the top cover holding seat is located above the filler holding seat. A first chamfer is provided on one side edge of the top of the filler holding seat. The installation frame has a "C" - shaped structure, and three limiting round rods are provided at the bottom of the upper horizontal plate of the installation frame, and the three limiting round rods are distributed vertically and parallelly. A first tension spring is sleeved on the limiting round rod. Three limiting shafts are provided on the vertical plate of the installation frame, and the limiting shafts correspond to the positions of the limiting round rods. Two air cylinders are fixedly installed on the top of the upper horizontal plate of the installation frame, and the two air cylinders are distributed symmetrically. A filling head is provided at the bottom end of the adjusting rod, and an installation sleeve is provided at the top end of the adjusting rod. The limiting round rod passes through the installation sleeve. A limiting groove is provided on the outer peripheral surface of the installation sleeve, and the limiting shaft is slidably connected with the limiting groove. A rotating ring is provided at the top end of the installation sleeve. A connecting frame is provided between the three adjusting rods. The connecting frame is of a rectangular frame structure, and three limiting rings are provided on the lower long rectangular rod of the connecting frame, and the limiting rings are slidably sleeved on the adjusting rod. Three bearing sleeves are provided on the upper long rectangular rod of the connecting frame, and the installation sleeve is rotationally connected with the bearing sleeve through the rotating ring. And the end of the telescopic rod of the air cylinder is connected with the upper long rectangular rod of the connecting frame. Moreover, the two ends of the first tension spring are respectively connected with the connecting frame and the installation frame. A second chamfer is provided on one side edge of the bottom of the blanking seat, and the second chamfer matches the first chamfer. A support plate is provided on one side of the blanking seat, and two limiting slide rods are slidably penetrated through the support plate, and the two limiting slide rods are distributed symmetrically. A fixing plate is provided between the top ends of the two limiting slide rods, and the fixing plate is connected with the medicine filling tank. A connecting circular plate is provided at the bottom end of the limiting slide rod. A second tension spring is sleeved on the limiting slide rod, and the two ends of the second tension spring are respectively connected with the connecting circular plate and the support plate. A fixing seat is provided at the bottom of the limiting frame, and the fixing seat is connected with the workbench. The limiting frame is of a rectangular through - cavity structure, and two guiding grooves are provided on the inner wall of the through - cavity of the limiting frame. The sliding frame has a "T" - shaped structure, and three connecting columns are provided on the relatively inner sides of the horizontal plates of the two sliding frames. A wiping cotton roller is provided at the end of the connecting column, and the upper and lower wiping cotton rollers respectively correspond to the top cover holding seat and the filler holding seat. A guiding plate is provided at the end of the vertical plate of the sliding frame, and the guiding plate is slidably connected with the limiting frame through the guiding groove. Tooth plates are provided on the relatively inner sides of the two guiding plates. The servo motor is provided with a rotating shaft rod, and the rotating shaft rod is rotatably connected with the limit frame through a bearing, and the rotating shaft rod is provided with a gear, and the gear is located between the two guide plates, and the gear is meshed and connected with the gear plate.

2. A roxithromycin capsule production device as claimed in claim 1, characterized in that , A rotating disk is rotatably installed in the medicine filling tank, and four metering seats are arranged on the rotating disk, and the four metering seats are distributed in a circular array, and the metering seats correspond to the positions of the discharge seat and the adjustment rod. A connecting groove is provided at the bottom of the medicine filling tank, and the discharge seat is slidably installed in the connecting groove.

3. The production process of the Roxithromycin Capsule Production Device according to claim 2, characterized in that: The following steps are involved:

1. First, during the process of filling the capsule bottom shell in the filling seat, the roxithromycin powder in the medicine filling tank enters the cylindrical cavity of the metering seat; 2. Two cylinders provide power to push the connecting frame downward, driving the three adjusting rods to adjust downward; 3. Through the rotational cooperation between the rotating ring and the bearing sleeve, the limiting shaft slides on the limiting groove, so that the installation sleeve drives the adjusting rod to rotate, and the filling head realizes the process of squeezing and discharging the powder into the cylindrical cavity of the metering seat; 4. Then, the second chamfer cooperates with the first chamfer to push the material discharging seat to slide upward along the limit slide rod, and the rebound pulling effect of the second tension spring is used to make the material discharging seat fit closely with the filling seat, so that the medicine powder is fully filled into the capsule shell of the filling seat; 5. In addition, the servo motor provides power to drive the rotating shaft to rotate, and the gears and the two toothed plates are meshed to drive the two guide plates and the sliding frame to slide along the guide groove; 6. The wiping cotton rollers are driven to adjust toward each other through the upper and lower sliding frames, and the empty slots of the capsule shell of the top cover holding seat and the filler holding seat are wiped at the same time to prevent the powder from contaminating the outer wall of the capsule.

Images