A mildew-proof agent for liquid feeding and its preparation method and application

Abstract

The present application relates to the technical field of feed additive, in particular to a kind of antifungal agent for liquid feeding and its preparation method and application.The antifungal agent for liquid feeding includes the following components by 1000 mass parts: bio-acid 150-300 parts, permeation acid 20-100 parts, plant extract 150-250 parts, mannose oligosaccharide 50-100 parts, glyceryl laurate 50-100 parts and solvent 200-550 parts.The antifungal agent for liquid feeding is combined according to certain proportion, and each component has synergistic effect, has good antifungal effect when used for liquid feeding, can effectively reduce the deterioration problem of residual feed in liquid feeding system, reduce harmful microorganism in feed, improve the digestibility of feed, thereby improve the production efficiency of animal, help the cost reduction and efficiency increase of breeding industry.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of feed additives, in particular to a mildew-proof agent for liquid feeding and a preparation method and application thereof. BACKGROUND

[0002] In the traditional pig raising process, liquid feeding is the main feeding method, and the proportion of liquid feeding in the pig industry in Europe is about 50-70%. In recent years, with the outbreak of swine fever and the advent of the era of banning antibiotics, cost reduction and efficiency improvement have become the core demand of the pig industry. Liquid feeding is adopted by many large-scale breeding enterprises due to its advantages of utilizing non-grain and other extensive feed resources, reducing dust pollution and lowering respiratory diseases in pigs, and reducing raw material process cost.

[0003] However, whether it is a pig farm using liquid feeding equipment on a large scale or a pig farm feeding in liquid form without equipment, due to the high moisture characteristics of liquid feed itself, they all face the problem of feed deterioration. The former often has residual equipment pipelines, and the latter often has feed deterioration in troughs under high temperature or long time without cleaning. The deteriorated feed contains a large amount of harmful bacteria and toxins produced by their metabolism, which can damage the immune system of animals and destroy intestinal integrity, causing economic losses to the breeding industry. Therefore, a strategy that can effectively alleviate the deterioration of liquid feeding mode is an important basis for popularizing liquid feeding in the pig industry and a powerful guarantee for cost reduction and efficiency improvement.

[0004] In view of this, the present application is proposed. SUMMARY

[0005] The purpose of the present application is to provide a mildew-proof agent for liquid feeding and a preparation method and application thereof, which can effectively reduce the deterioration problem of residual feed in the liquid feeding system.

[0006] In order to achieve the above purpose of the present application, the following technical solution is adopted:

[0007] In one aspect of the present application, a mildew-proof agent for liquid feeding is provided, comprising the following components per 1000 parts by mass:

[0008] 150-300 parts of biological acid, 20-100 parts of permeation acid, 150-250 parts of plant extract, 50-100 parts of mannose oligosaccharide, 50-100 parts of glyceryl laurate, and 200-550 parts of solvent.

[0009] The mildew-proof agent for liquid feeding is combined according to a certain proportion, and the components synergize with each other. When used for liquid feeding, it has good mildew-proof effect, reduces the cost of liquid feeding, and can effectively reduce the deterioration problem of residual feed in the liquid feeding system.

[0010] Another aspect of the present invention relates to a method for preparing the aforementioned antifungal agent for liquid feeding, comprising the following steps:

[0011] Mix all components thoroughly.

[0012] The method for preparing the antifungal agent is simple, easy to operate, requires no complex processes or equipment, and is low in cost.

[0013] Another aspect of the present invention relates to a liquid feed, comprising the aforementioned antifungal agent for liquid feeding or an antifungal agent for liquid feeding prepared by the aforementioned method for preparing the antifungal agent for liquid feeding.

[0014] Another aspect of the invention relates to a method for liquid feeding of pigs, wherein the liquid feed is fed to the pigs.

[0015] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0016] (1) The anti-mold agent for liquid feeding provided by the present invention combines the components in a certain proportion and the components work synergistically. When used for liquid feeding, it has a good anti-mold effect, reduces the cost of liquid feeding, and can effectively reduce the problem of residual feed deterioration in liquid feeding systems.

[0017] (2) The antifungal agent for liquid feeding provided by this invention is more effective for this feeding mode. Conventional solid dry feed is far less prone to mold and bacterial growth than liquid feed (which has a high moisture content). Liquid feeding equipment and pipelines have many dead corners, making residues easy to accumulate. The antifungal agent of this invention not only inhibits bacteria but also breaks down bacterial films, reducing resistance during feed transport and maintaining the usability of equipment and pipelines. Furthermore, the antifungal agent of this invention can improve the digestibility of liquid feed. The use of bio-acids provides a better environment for digestive enzymes, improving feed digestibility. Moreover, because the composition of this antifungal agent is carefully considered, it broadens the antibacterial spectrum and provides growth substrates for beneficial bacteria such as lactic acid bacteria. It not only directly kills bacteria but also indirectly achieves antifungal and bactericidal effects through competitive inhibition, combining both antibacterial and nutritional effects. Detailed Implementation

[0018] The technical solutions of the present application will be described clearly and completely below in conjunction with specific embodiments, but those skilled in the art will understand that the following described embodiments are part of the embodiments of the present application, rather than all the embodiments, and are only used to illustrate the present application, and should not be regarded as limiting the scope of the present application. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without making creative efforts are within the scope of protection of the present application. If specific conditions are not indicated in the embodiments, the conventional conditions or the conditions recommended by the manufacturer are used. If the reagents or instruments used are not indicated by the manufacturer, they are all conventional products that can be purchased on the market.

[0019] In one aspect of the present application, a mold inhibitor for liquid feeding, comprising the following components per 1000 parts by mass:

[0020] The biological acid is 150-300 parts by mass, the permeation acid is 20-100 parts by mass, the plant extract is 150-250 parts by mass, the manno-oligosaccharide is 50-100 parts by mass, the glyceryl laurate is 50-100 parts by mass, and the solvent is 200-550 parts by mass.

[0021] In some specific embodiments, the biological acid may, for example, be, but is not limited to, any one of the point values of 150 parts, 180 parts, 200 parts, 230 parts, 250 parts, 280 parts or 300 parts by mass, or a range value between any two of them.

[0022] In some specific embodiments, the permeation acid may, for example, be, but is not limited to, any one of the point values of 20 parts, 30 parts, 40 parts, 50 parts, 60 parts, 70 parts, 80 parts, 90 parts or 100 parts by mass, or a range value between any two of them.

[0023] In some specific embodiments, the plant extract may, for example, be, but is not limited to, any one of the point values of 150 parts, 170 parts, 190 parts, 210 parts, 230 parts or 250 parts by mass, or a range value between any two of them.

[0024] In some specific embodiments, the manno-oligosaccharide may, for example, be, but is not limited to, any one of the point values of 50 parts, 60 parts, 70 parts, 80 parts, 90 parts or 100 parts by mass, or a range value between any two of them.

[0025] In some specific embodiments, the glyceryl laurate may, for example, be, but is not limited to, any one of the point values of 50 parts, 60 parts, 70 parts, 80 parts, 90 parts or 100 parts by mass, or a range value between any two of them.

[0026] In some embodiments, the solvent can be, for example, but not limited to, any one of 200 parts, 230 parts, 250 parts, 280 parts, 300 parts, 330 parts, 350 parts, 380 parts, 400 parts, 430 parts, 450 parts, 480 parts, 500 parts, 530 parts, or 550 parts, or a range value between any two of them in mass parts.

[0027] The mold inhibitor for liquid feeding is combined with the components in a certain proportion, and the components synergize with each other, and has a good mold-proof effect when used for liquid feeding, reduces the cost of liquid feeding, and effectively reduces the deterioration problem of residual feed in the liquid feeding system with a small amount of addition in the liquid feed.

[0028] The mold inhibitor of the present application can play a better effect on liquid feeding mode, and the degree of mold growth of conventional solid dry feed is much lower than that of liquid feed (with high moisture content). The device pipeline of liquid feeding has many dead angles and is easy to be left. The mold inhibitor of the present application can not only inhibit bacteria, but also break the bacterial biofilm, reduce the resistance of feed transportation, and maintain the usability of the device pipeline. On the other hand, the mold inhibitor of the present application can also improve the digestibility of liquid feed. The use of biological acid can provide a better environment for digestive enzymes, and improve the digestibility of feed. Furthermore, the components of the mold inhibitor are carefully selected, which not only expands the bacteriostatic spectrum, but also provides a growth substrate for beneficial bacteria such as lactic acid bacteria, directly kills bacteria, and indirectly inhibits mold and bacteria through competition, and has the effects of bacteriostasis and nutrition.

[0029] The mold inhibitor plays a role in inhibiting bacteria by biological acid and lauryl glyceride, reduces harmful microorganisms, breaks the biofilm formed between bacteria by permeabilizing acid, reduces the wrapping of feed in the pipeline, and reduces the resistance of feed line flow.

[0030] The mold inhibitor supplies mannose oligosaccharide to beneficial bacteria as a substrate, improves the load of beneficial bacteria, and further combines with the improvement of feed digestibility by acid to protect the freshness and nutritional value of feed from multiple dimensions, and provides protection for the implementation of liquid feeding. Mannose oligosaccharide can settle E. coli, reduce the colonization of E. coli in the intestinal tract, and reduce the damage of E. coli to the intestinal tract. In addition, as a preferred substrate of probiotics, mannose oligosaccharide is beneficial to the growth of probiotics, especially lactic acid bacteria. On the one hand, lactic acid bacteria can reproduce and colonize harmful bacteria, and on the other hand, lactic acid bacteria can also inhibit the growth of harmful bacteria by producing acid to reduce pH.

[0031] Lauryl glyceride, as one of medium-chain fatty acids, has a better inhibitory effect on gram-positive bacteria, and can better inhibit gram-negative bacteria in combination with biological acid + permeabilizing acid. The addition of biological acid and permeabilizing acid can more comprehensively improve the bacteriostatic spectrum.

[0032] The plant extract has the effect of inhibiting harmful microorganisms such as bacteria and molds, and can also scavenge free radicals and play the role of anti-inflammatory and anti-oxidation.

[0033] Further, per 1000 parts by mass of the antifungal agent for liquid feeding, the following components are included:

[0034] The biological acid is 180-250 parts, the permeation acid is 40-80 parts, the plant extract is 180-230 parts, the mannose oligosaccharide is 60-90 parts, the glyceryl laurate is 60-90 parts, and the solvent is 300-450 parts.

[0035] Further, the biological acid includes, but is not limited to, at least one of formic acid, acetic acid, benzoic acid or lactic acid.

[0036] Further, the biological acid includes formic acid, acetic acid, benzoic acid and lactic acid in a mass ratio of (1-3):(3-5):(1-3):(1-3), for example, but not limited to, 1:5:1:3, 2:4:2:2 or 3:3:3:1.

[0037] The present application optimizes the compounding relationship and proportion of each acid of the biological acid, and improves the bacteriostatic effect.

[0038] Further, the permeation acid includes, but is not limited to, at least one of fumaric acid, citric acid or cinnamic acid.

[0039] Further, the permeation acid includes fumaric acid, citric acid and cinnamic acid in a mass ratio of (4-6):(2-4):(1-3), for example, but not limited to, 4:4:1, 5:3:2 or 6:2:3.

[0040] The permeation acid has a permeation effect, can better open the outer membrane of the cell wall of gram-negative bacteria, and help other bacteriostatic substances to enter the bacteria more effectively to play a role. Generally, the content is low, and reasonable compounding can play a good permeation effect.

[0041] Further, the plant extract includes, but is not limited to, at least one of carvacol, eugenol, ferulic acid or baicalin.

[0042] Further, the plant extract includes carvacol, eugenol, ferulic acid and baicalin in a mass ratio of (3-5):(2-4):(1-3):1, for example, but not limited to, 3:4:1, 4:3:2 or 5:2:3.

[0043] Further, the solvent includes, but is not limited to, anhydrous ethanol 50-150 parts and double distilled water 150-400 parts in terms of mass fraction.

[0044] In some embodiments, the anhydrous ethanol can be, for example, but not limited to, any one of 50 parts, 60 parts, 70 parts, 80 parts, 90 parts, 100 parts, 110 parts, 120 parts, 130 parts, 140 parts, or 150 parts, or a range value between any two of them, in terms of mass fraction.

[0045] In some embodiments, the double distilled water can be, for example, but not limited to, any one of 150 parts, 180 parts, 200 parts, 230 parts, 250 parts, 280 parts, 300 parts, 330 parts, 350 parts, 380 parts, or 400 parts, or a range value between any two of them, in terms of mass fraction.

[0046] Another aspect of the present application also relates to a preparation method of the mold inhibitor for liquid feeding, comprising the following steps:

[0047] Mixing the components.

[0048] Further, the mixing includes:

[0049] (1) dissolving the plant extract in anhydrous ethanol;

[0050] (2) dissolving the glyceryl laurate in anhydrous ethanol;

[0051] (3) dissolving the benzoic acid in double distilled water, heating and stirring, cooling at room temperature, and then adding formic acid, acetic acid, benzoic acid, and lactic acid;

[0052] (4) mixing fumaric acid, citric acid, and cinnamic acid;

[0053] (5) dissolving the mannan oligosaccharide in double distilled water;

[0054] (6) mixing the above parts together while stirring.

[0055] According to the above mixing order, the components can be fully dissolved, and the mold inhibitor can have sufficient effective components.

[0056] Another aspect of the present application also relates to a liquid feed, comprising the mold inhibitor for liquid feeding or the mold inhibitor for liquid feeding prepared by the preparation method of the mold inhibitor for liquid feeding.

[0057] Further, the liquid feed contains 0.2wt% to 1wt% (for example, but not limited to, any one of 0.2wt%, 0.4wt%, 0.6wt%, 0.8wt%, or 1wt%, or a range value between any two of them) of the mold inhibitor for liquid feeding. At this content, the occurrence of moldy liquid feed can be reduced.

[0058] Another aspect of the present application also relates to a method for liquid feeding of pigs, wherein the liquid feed is fed to the pigs.

[0059] Embodiments of the present application will be described in detail below with reference to Examples, but those skilled in the art will appreciate that the following Examples are intended to be illustrative only and should not be viewed as limiting the scope of the present application. Where specific conditions are not mentioned in the Examples, they are carried out under conventional conditions or conditions recommended by the manufacturer. Where the manufacturer of the reagent or instrument is not mentioned, it is a conventional product that can be obtained commercially.

[0060] Example 1

[0061] The mold inhibitor for liquid feeding provided in this Example includes the following components per 1000 parts by mass:

[0062] 300 parts of bio-acid, 30 parts of permeation acid, 150 parts of plant extract, 100 parts of manno-oligosaccharide, 50 parts of glyceryl laurate, and a solvent;

[0063] The bio-acid includes formic acid, acetic acid, benzoic acid, and lactic acid at a mass ratio of 2:4:2:2;

[0064] The permeation acid includes fumaric acid, citric acid, and cinnamic acid at a mass ratio of 5:3:2;

[0065] The plant extract includes carvacrol, eugenol, ferulic acid, and baicalin at a mass ratio of 4:3:2:1.

[0066] The method for preparing the mold inhibitor for liquid feeding provided in this Example includes the following steps:

[0067] (1) dissolving the plant extract in 50 parts of anhydrous ethanol;

[0068] (2) mixing the glyceryl laurate with 20 parts of anhydrous ethanol while stirring the solution;

[0069] (3) dissolving the benzoic acid in 100 parts of double-distilled water while stirring under heating, cooling at room temperature, and then adding the formic acid, acetic acid, benzoic acid, and lactic acid;

[0070] (4) mixing the fumaric acid, citric acid, and cinnamic acid;

[0071] (5) dissolving the manno-oligosaccharide in 200 parts of water while stirring the portion;

[0072] (6) mixing the above portions together while stirring, which is the complete liquid mold inhibitor.

[0073] Example 2

[0074] The fungicide for liquid feeding provided by the embodiment comprises the following components per 1000 parts by mass:

[0075] biological acid 250 parts, permeation acid 100 parts, plant extract 200 parts, mannose oligosaccharide 50 parts, glyceryl laurate 100 parts, and solvent;

[0076] The biological acid comprises formic acid, acetic acid, benzoic acid, and lactic acid at a mass ratio of 2:4:2:2;

[0077] The permeation acid comprises fumaric acid, citric acid, and cinnamic acid at a mass ratio of 5:3:2;

[0078] The plant extract comprises carvacrol, eugenol, ferulic acid, and baicalin at a mass ratio of 4:3:2:1.

[0079] The preparation method of the fungicide for liquid feeding provided by the embodiment comprises the following steps:

[0080] (1) dissolving the plant extract in 70 parts of anhydrous ethanol;

[0081] (2) mixing the glyceryl laurate with 30 parts of anhydrous ethanol and stirring the solution while mixing;

[0082] (3) dissolving the benzoic acid in 100 parts of double-distilled water, stirring while heating, cooling at room temperature, and then adding the formic acid, acetic acid, benzoic acid, and lactic acid;

[0083] (4) mixing the fumaric acid, citric acid, and cinnamic acid;

[0084] (5) dissolving the mannose oligosaccharide in 100 parts of water and stirring while mixing;

[0085] (6) mixing the above parts together and stirring while mixing, to obtain the complete liquid fungicide.

[0086] Embodiment 3

[0087] The fungicide for liquid feeding provided by the embodiment comprises the following components per 1000 parts by mass:

[0088] biological acid 300 parts, permeation acid 20 parts, plant extract 150 parts, mannose oligosaccharide 50 parts, glyceryl laurate 100 parts, and solvent;

[0089] The biological acid comprises formic acid, acetic acid, benzoic acid, and lactic acid at a mass ratio of 1:3:1:1;

[0090] The permeation acid comprises fumaric acid, citric acid, and cinnamic acid at a mass ratio of 4:2:1;

[0091] The plant extract includes carvacol, eugenol, ferulic acid and baicalin in a mass ratio of 3:2:1:1.

[0092] The preparation method of the antifungal agent for liquid feeding provided in the embodiment includes the following steps:

[0093] (1) dissolving the plant extract in 100 parts of anhydrous ethanol;

[0094] (2) mixing glyceryl laurate with 30 parts of anhydrous ethanol and stirring the solution while mixing;

[0095] (3) dissolving benzoic acid in 150 parts of double-distilled water, stirring while heating, cooling at room temperature, and then adding formic acid, acetic acid, benzoic acid and lactic acid;

[0096] (4) mixing fumaric acid, citric acid and cinnamic acid;

[0097] (5) dissolving mannose oligosaccharide in 100 parts of water and stirring while mixing;

[0098] (6) mixing the above parts together and stirring while mixing, which is the complete liquid antifungal agent.

[0099] Embodiment 4

[0100] Bio-acid 150 parts, permeation acid 100 parts, plant extract 250 parts, mannose oligosaccharide 100 parts, glyceryl laurate 50 parts and solvent;

[0101] The bio-acid includes formic acid, acetic acid, benzoic acid and lactic acid in a mass ratio of 3:3:1:3;

[0102] The permeation acid includes fumaric acid, citric acid and cinnamic acid in a mass ratio of 6:2:3;

[0103] The plant extract includes carvacol, eugenol, ferulic acid and baicalin in a mass ratio of 5:4:3:1.

[0104] The preparation method of the antifungal agent for liquid feeding provided in the embodiment includes the following steps:

[0105] (1) dissolving the plant extract in 100 parts of anhydrous ethanol;

[0106] (2) mixing glyceryl laurate with 50 parts of anhydrous ethanol and stirring the solution while mixing;

[0107] (3) dissolving benzoic acid in 100 parts of double-distilled water, stirring while heating, cooling at room temperature, and then adding formic acid, acetic acid, benzoic acid and lactic acid;

[0108] (4) mixing fumaric acid, citric acid and cinnamic acid;

[0109] (5) Dissolve the mannose oligosaccharide in 100 parts of water, and mix and stir the part;

[0110] (6) Mix the above parts together, and mix and stir, to obtain the complete liquid antifungal agent.

[0111] Comparative Example 1

[0112] The difference between this comparative example and Example 1 is that no biological acid is added.

[0113] Comparative Example 2

[0114] The difference between this comparative example and Example 1 is that no mannose oligosaccharide is added.

[0115] Comparative Example 3

[0116] The difference between this comparative example and Example 1 is that no permeation acid is added.

[0117] Comparative Example 4

[0118] The difference between this comparative example and Example 1 is that the biological acid comprises formic acid, acetic acid, benzoic acid and lactic acid in a mass ratio of 6:1:4:4.

[0119] Comparative Example 5

[0120] The difference between this comparative example and Example 1 is that the permeation acid comprises fumaric acid, citric acid and cinnamic acid in a mass ratio of 1:5:4.

[0121] Comparative Example 6

[0122] The difference between this comparative example and Example 1 is that the plant extract comprises carvacrol, eugenol, ferulic acid and baicalin in a mass ratio of 2:5:4:1.

[0123] Comparative Example 7

[0124] The antifungal agent for liquid feeding provided by this comparative example comprises the following components per 1000 parts by mass:

[0125] biological acid 400 parts, permeation acid 150 parts, plant extract 100 parts, mannose oligosaccharide 40 parts, glyceryl laurate 150 parts and solvent 160 parts;

[0126] The preparation method is the same as that of Example 1.

[0127] Experimental Example 1

[0128] The antifungal agent prepared in the examples and the comparative examples was added to the liquid feed in an amount of 0.5 wt%, and a commercially available antifungal agent was added to the liquid feed in an amount of 0.5 wt% as a comparative example, and a feed group without the addition of the antifungal agent was used as a blank control group. The groups were placed in a constant temperature and humidity biochemical incubator, the humidity was (80±5)%, and the temperature was (33±2)℃. The results showed that the control group had obvious alcohol smell in 12-18h, the antifungal agent group had no obvious odor in 72h, and the comparative example had obvious alcohol smell in 48h. The samples of each group at 0d, 3d, 6d, 9d, 12d and 15d were taken to detect the number of bacteria and molds, and the results are shown in Tables 1 and 2.

[0129] Table 1

[0130]

[0131] Table 2

[0132]

[0133]

[0134] As can be seen from the data in Tables 1 and 2, within the scope defined in the present application, the antifungal agent has better bacteriostatic and mold-proof effect, and each component plays its own characteristics, and the combination is more complementary and comprehensive in bacteriostatic and mold-proof.

[0135] Experimental Example 2

[0136] 96 healthy 28-day-old (Du × Chang × Large) weaned piglets were selected for the test. The piglets were divided into 4 treatments according to body weight and gender, i.e. a control group (without the addition of the antifungal agent), a test group 1 (adding 0.5 wt% of the antifungal agent in Example 1), a test group 2 (adding 0.5 wt% of the antifungal agent in Example 2), and a commercially available antifungal agent (adding an amount of 0.5 wt%). There were 6 replicates for each treatment, and 4 piglets in each replicate, and the gender ratio of all replicates was consistent. Three days before the start of the test was a pre-feeding period to adapt the piglets to the environment and the feed. After the start of the formal test, the piglets in each treatment were fed the corresponding feed, and the formal test period was 28 days. After the end of the experiment, the growth performance of the piglets and the apparent digestibility of the feed nutrients were calculated, and the results are shown in Table 3.

[0137] Table 3

[0138] Item Control Example 1 Example 2 Commercially available Average daily gain, ADG, g / d 356 ± 16 c ]] 399 ± 17 a ]] 407 ± 17 a ]] 375 ± 20 b ]] Average daily feed intake, ADFI, g / d 540 ± 19 c ]] 579 ± 21 a ]] 588 ± 23 a ]] 554 ± 18 b <!-- 7 -->]] Feed:gain, F:G 1.52 ± 0.08 b ]] 1.45 ± 0.06 a ]] 1.44 ± 0.09 a ]] 1.47 ± 0.10 ab ]] Diarrhea rate (%) 5.34 ± 0.26 c ]] 1.67 ± 0.14 a ]] 1.58 ± 0.18 b ]] 2.75 ± 0.16 b ]] Apparent digestibility of dry matter (%) 80.56 86.53 86.97 83.21 Apparent digestibility of crude protein (%) 78.24 84.36 83.88 80.19 Apparent digestibility of crude fat (%) 49.45 58.32 57.55 52.18 Apparent digestibility of crude fiber (%) 44.66 52.16 53.77 47.80 Feed in the trough pH 6.34 4.89 4.74 5.68

[0139] As can be seen from Table 3, the addition of the antifungal agent of the examples improves the daily weight gain and feed intake of the pigs, reduces the diarrhea rate and the feed conversion ratio, and improves the digestibility, indicating that the antifungal agent provided by the present application has a significant mold-proof effect and is beneficial to the growth of pigs. Compared with the commercially available antifungal agent, the antifungal agent provided by the present application has a better feeding effect.

[0140] Although the present application has been described and illustrated with a certain degree of particularity, it is understood that the present application has been made by way of examples only and that numerous changes in the details of execution can be made by those skilled in the art without departing from the spirit and scope of the application. It is therefore intended to cover in the appended claims all such changes and modifications that come within the scope of the application.

Claims

1. A fungicide for liquid feeding, characterized by comprising: Per 1000 parts by mass, the following components are included: biological acid 150-300 parts, permeation acid 20-100 parts, plant extract 150-250 parts, mannose oligosaccharide 50-100 parts, glyceryl laurate 50-100 parts, and solvent 200-550 parts; the biological acid includes formic acid, acetic acid, benzoic acid, and lactic acid in a mass ratio of (1-3):(3-5):(1-3):(1-3); the permeation acid includes fumaric acid, citric acid, and cinnamic acid in a mass ratio of (4-6):(2-4):(1-3); the plant extract includes carvacol, eugenol, ferulic acid, and baicalin in a mass ratio of (3-5):(2-4):(1-3):

1.

2. The mold inhibitor for liquid feeding according to claim 1, characterized by, Per 1000 parts by mass of the antifungal agent for liquid feeding, the following components are included: biological acid 180-250 parts, permeation acid 40-80 parts, plant extract 180-230 parts, mannose oligosaccharide 60-90 parts, glyceryl laurate 60-90 parts, and solvent 300-450 parts.

3. The mold inhibitor for liquid feeding according to claim 1 or 2, characterized by, The solvent includes anhydrous ethanol 50-150 parts and double-distilled water 150-400 parts, in terms of parts by mass.

4. The method for preparing an antifungal agent for liquid feeding according to any one of claims 1 to 3, characterized by, The method includes the following steps: mixing the components.

5. A liquid feed, characterized in that, The antifungal agent for liquid feeding is prepared by the method of any one of claims 1-3 or the method of claim 4.

6. The liquid feed according to claim 5, characterized in that, The liquid feed contains 0.2wt%-1wt% of the antifungal agent for liquid feeding.

7. A method of liquid feeding pigs, characterized in that The liquid feed of claim 5 or 6 is fed to pigs.

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