Conveying device

Abstract

Embodiments of the present invention relate to the technical field of medical devices and disclose a conveying device. When an operator continuously operates the conveying device to cause a movable member to continuously move, the force exerted by the buffer member on the wire fixing member increases slowly, and the tension of the driving wire also increases correspondingly slowly. This prevents damage to human tissues, organs, or other parts of the prosthesis on which the movable member acts. Furthermore, because the buffer member's own elastic properties are generally much smaller than the tensile modulus of the driving wire, the deformation of the driving wire caused by the force exerted by the wire fixing member (i.e., the transmission of the force exerted by the buffer member to the wire fixing member) is much smaller than the axial displacement of the second movable member, thereby preventing breakage of the driving wire.

Description

Technical Field

[0001] The embodiments of the present invention relate to the technical field of medical devices, and in particular to a delivery device. Background Art

[0002] The mitral valve is located between the left atrium and left ventricle. During diastole, the mitral valve opens, allowing blood from the left atrium to flow into the left ventricle. During systole, the mitral valve closes, allowing pumped blood to flow into the aorta and prevent it from flowing back into the left atrium. This means the mitral valve acts as a one-way valve. If the mitral valve fails to close completely during systole, some blood from the left ventricle can flow back into the left atrium, a condition known as mitral regurgitation (MR). When MR occurs, the mitral valve is no longer functioning as a one-way valve. During systole, some blood flows back into the left atrium, reducing forward blood flow and limiting the heart's pumping function. Severe MR can lead to complications such as atrial fibrillation, pulmonary hypertension, congestive heart failure, blood clots, and stroke. Therefore, patients with severe MR urgently need effective treatment.

[0003] Traditionally, MR is treated through open-chest surgery. One such procedure involves suturing the edges of the mitral valve leaflets directly to each other (called the "Alfieri" suture), a difficult procedure that is prone to numerous complications.

[0004] With the advancement of interventional technology, various interventional procedures have emerged, such as transcatheter edge-to-edge mitral valve repair (TEER), which mimics the aforementioned "Alfieri" suture. In the TEER procedure, the transcatheter mitral valve repair system consists of a mitral valve clip and a delivery device. The mitral valve clip is delivered via the delivery device, guided by three-dimensional ultrasound and DSA, through the femoral vein, across the atrial septum, and into the left atrium and left ventricle. The clip then grasps the edges of the mitral valve leaflets (i.e., the anterior and posterior leaflets), reducing the mitral valve's single, open orifice during systole and reducing mitral regurgitation. Compared to surgical edge-to-edge repair, TEER offers advantages such as less trauma, shorter operative time, and improved safety, and is expected to improve the cure rate of MR.

[0005] However, existing transcatheter mitral valve repair systems still have many shortcomings. For example, after the mitral valve clip has clamped the valve leaflets, if the operator continues to operate the delivery device, the clamping force on the valve leaflets will rapidly increase, potentially damaging the leaflets. Furthermore, continued operation of the delivery device may also cause the actuator wire to break. Summary of the Invention

[0006] The purpose of the embodiments of the present invention is to provide a delivery device to solve the problem that after the mitral valve clip clamps the valve leaflets, if the operation continues, the valve leaflets may be damaged or the driving wire may be broken.

[0007] To solve the above technical problems, the first aspect of the present invention provides a delivery device for delivering a prosthesis having a movable part, comprising:

[0008] The cam is adapted to move the movable member relative to the outer shell and to move the movable member to a position adjacent to the outer shell, wherein the movable member is adapted to move relative to the outer shell in a direction parallel to the axis of the movable member and relative to the outer shell. The cam is adapted to move relative to the outer shell and to move relative to the outer shell.

[0009] Optionally, the movable member includes an axially extending movable channel, the movable channel includes a first sub-channel and a second sub-channel, the first sub-channel is located on the distal side of the second sub-channel, and the inner diameter of the first sub-channel is smaller than the inner diameter of the second sub-channel, so as to form a first abutment surface at the connection between the first sub-channel and the second sub-channel; the wire fixing member includes a first section and a second section, the outer diameter of the first section is smaller than the outer diameter of the second section, so as to form a second abutment surface at the connection between the first section and the second section, the first section is partially accommodated in the first sub-channel, the second section is partially accommodated in the second sub-channel, and the buffer member is located between the first abutment surface and the second abutment surface.

[0010] Optionally, the moving member includes an axially extending moving channel, the end face of the proximal end of the moving member is defined as a first abutment surface, the wire fixing member includes a first section and a second section, the outer diameter of the first section is smaller than the outer diameter of the second section, so as to form a second abutment surface at the connection between the first section and the second section, the first section is partially accommodated in the moving channel, and the second section is located on the proximal side of the moving member and outside the moving channel; the buffer member is located between the first abutment surface and the second abutment surface.

[0011] Optionally, the limiting assembly includes a slide groove provided at the proximal end of the movable member and extending axially, and a sliding portion provided at the proximal end of the wire fixing member, wherein the sliding portion is movably provided in the slide groove to couple the movable member and the wire fixing member.

[0012] Optionally, there are multiple slide grooves, which are spaced apart along the circumference of the movable member; there are multiple sliding parts, which are spaced apart along the circumference of the wire fixing member; and at least one sliding part is accommodated in at least part of the slide grooves.

[0013] Optionally, the limiting assembly includes a snap-fit ​​cover and a limiting member arranged at the proximal end of the movable member, the snap-fit ​​cover abuts the proximal end of the wire fixing member and couples the limiting member so that the movable member and the wire fixing member remain axially relatively stationary under the action of the preload force.

[0014] Optionally, the snap-on cover includes an abutting portion and a limiting portion that are fixedly connected, the abutting portion is provided at a proximal end of the limiting portion for abutting against a proximal end of the wire fixing member, and the limiting portion is used for coupling with the limiting member.

[0015] Optionally, the snap-on cover further includes a connecting portion fixedly connecting the abutting portion and the limiting portion, the connecting portion being circumferentially arranged along the abutting portion and extending axially; the limiting portion is located at one end of the connecting portion away from the abutting portion, and the limiting portion is used to engage with the limiting member.

[0016] Optionally, the limiting portion is a first protrusion extending radially toward the moving part, and the limiting part is a second protrusion arranged along the circumference of the moving part and extending radially toward the snap-fit ​​cover, the first protrusion includes a first sliding surface and a third abutting surface, the first sliding surface is located on the distal side of the third abutting surface; the second protrusion includes a second sliding surface and a fourth abutting surface, the second sliding surface is located on the proximal side of the fourth abutting surface; the first sliding surface is configured to slide relative to the second sliding surface when the snap-fit ​​cover is engaged with the limiting part; the third abutting surface is configured to abut against the fourth abutting surface after the snap-fit ​​cover is engaged with the limiting part.

[0017] Optionally, the buffer member is an elastic member, a hydraulic buffer or a pneumatic buffer.

[0018] Optionally, the elastic member is a compression spring or a rubber ring sleeved on the wire fixing member.

[0019] A second aspect of the present invention provides another delivery device, comprising:

[0020] a housing; a drive assembly comprising a moving member, the moving member being movably accommodated in the housing relative to the housing along the axial direction of the housing; a wire fixing member, the wire fixing member being movably accommodated in the moving member; a driving wire, the proximal end of the driving wire being fixed to the wire fixing member, and the distal end of the driving wire being used to be detachably connected to the prosthesis; the moving member drives the driving wire to move axially via the wire fixing member to drive the movable member to move; a limiting assembly comprising a first limiting portion provided on the moving member and a second limiting portion provided on the wire fixing member; a buffer member, the buffer member being located between the moving member and the second limiting portion, the buffer member being used to apply a first pre-tightening force to the moving member, and applying a second pre-tightening force to the wire fixing member through the second limiting portion, so that the moving member and the wire fixing member have a movement tendency away from each other, the first pre-tightening force and the second pre-tightening force being equal in magnitude and opposite in direction; the limiting assembly being configured to prevent the wire fixing member from moving toward the proximal end under the action of the second pre-tightening force by cooperating with the first limiting portion and the second limiting portion.

[0021] Optionally, the first limiting portion is a sliding groove provided at the proximal end of the movable member and extending axially, and the second limiting portion is a sliding portion provided at the proximal end of the wire fixing member, and the sliding portion is movably provided in the sliding groove.

[0022] Optionally, the movable member includes an axially extending movable channel, the movable channel includes a first sub-channel and a second sub-channel, the first sub-channel is located on the distal side of the second sub-channel, and the inner diameter of the first sub-channel is smaller than the inner diameter of the second sub-channel, so as to form a first abutment surface at the connection between the first sub-channel and the second sub-channel; the wire fixing member is accommodated in the movable channel, and the buffer member is located between the first abutment surface and the distal end face of the sliding portion.

[0023] Compared with the related art, the embodiments of the present invention are as follows: when the operator continuously operates the conveying device to cause the movable part to continue to move, especially after the tension of the driving wire is greater than the pre-tightening force, the force exerted by the buffer member on the wire fixing part increases slowly, and accordingly, the tension of the driving wire also increases slowly, thereby preventing damage to the human tissue organs or other parts of the prosthesis acted upon by the movable part; on the other hand, since the elastic properties of the buffer member itself are generally much smaller than the tensile modulus of the driving wire, the deformation of the driving wire caused by the force exerted by the wire fixing member (i.e., the transmission of the force exerted by the buffer member to the wire fixing member) is much smaller than the axial displacement of the second movable part, which can prevent the driving wire from breaking and provide good protection for the driving wire. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] One or more embodiments are exemplarily illustrated by pictures in the corresponding drawings. These exemplifications do not constitute limitations on the embodiments. Elements with the same reference numerals in the drawings are represented as similar elements. Unless otherwise stated, the figures in the drawings do not constitute proportional limitations.

[0025] Figure 1 This is a schematic diagram of delivering a mitral valve clip to the mitral valve through a catheter so that the mitral valve clip clamps the anterior and posterior leaflets of the mitral valve;

[0026] Figure 2 This is a schematic diagram of the mitral valve clip clamping the mitral valve leaflets;

[0027] Figure 3 This is a schematic diagram of the structure of the mitral valve clip when the arms are retracted;

[0028] Figure 4 This is a schematic diagram of the structure of the mitral valve clip when the arms are opened;

[0029] Figure 5 is a cross-sectional view of the proximal end portion of a delivery device of the prior art in the axial direction;

[0030] Figure 6 is a schematic side view of a conveying device according to an embodiment of the present invention;

[0031] Figure 7 is a cross-sectional view of the proximal end portion of the delivery device according to an embodiment of the present invention in the axial direction;

[0032] Figure 8 is a cross-sectional view of a moving member of a conveying device according to an embodiment of the present invention in the axial direction;

[0033] Figure 9 is a cross-sectional view of a wire fixing member of a delivery device according to an embodiment of the present invention in the axial direction;

[0034] Figure 10 is a cross-sectional view of the snap-fit ​​cover of the conveying device according to an embodiment of the present invention in the axial direction;

[0035] Figure 11 is a cross-sectional view of the proximal end portion of the housing of the delivery device according to an embodiment of the present invention in the axial direction;

[0036] Figure 12 is a cross-sectional view of a driving member of a conveying device according to an embodiment of the present invention in the axial direction;

[0037] Figure 13 FIG. 1 is a cross-sectional view of the proximal end portion of a delivery device according to another embodiment of the present invention in the axial direction. DETAILED DESCRIPTION

[0038] To make the purpose, technical solutions, and advantages of the embodiments of the present invention more clear, each embodiment of the present invention will be described in detail below with reference to the accompanying drawings. However, those skilled in the art will appreciate that in each embodiment of the present invention, many technical details are provided to help readers better understand the present application. However, even without these technical details and various changes and modifications based on the following embodiments, the technical solutions claimed in the present application can still be implemented.

[0039] In the embodiments of the present invention, terms such as "upper," "lower," "left," "right," "front," "back," "top," "bottom," "inner," "outer," "center," "vertical," "horizontal," "transverse," and "longitudinal" to indicate directions or positions are based on the directions or positions shown in the accompanying drawings. These terms are primarily intended to better describe the present invention and its embodiments and are not intended to limit the devices, elements, or components indicated to having a specific direction, or to being constructed or operated in a specific direction.

[0040] Furthermore, some of the above terms may be used to express other meanings besides indicating a position or location. For example, the term "on" may also be used to indicate a dependency or connection in certain circumstances. Those skilled in the art will understand the specific meanings of these terms in the present invention based on the specific circumstances.

[0041] Furthermore, the terms "installed," "set," "provided with," "opened," "connected," and "connected" should be interpreted broadly. For example, they can refer to fixed connections, removable connections, or integral structures; mechanical connections or electrical connections; direct connections or indirect connections through an intermediary; or internal communication between two devices, elements, or components. Those skilled in the art will understand the specific meanings of these terms in the present invention based on specific circumstances.

[0042] Furthermore, the terms "first," "second," etc., are primarily used to distinguish between different devices, elements, or components (which may or may not be of the same type and configuration), and are not intended to indicate or imply the relative importance or quantity of the devices, elements, or components indicated. Unless otherwise specified, "plurality" means two or more.

[0043] The present invention is not particularly limited to prostheses; the prosthesis may be a mitral valve clip used to clamp the mitral valve leaflets to treat mitral regurgitation, a valve clip used to clamp other valves, such as a tricuspid valve clip used to clamp the tricuspid valve to treat tricuspid regurgitation, or other prostheses with movable parts. The present invention will be explained below using a mitral valve clip as an example of a prosthesis.

[0044] See also Figures 1 to 4The mitral valve clip 100 includes a base 110, a clamping arm 120 (i.e., a movable part) and a clip 130. There are two clamping arms 120 and two clips 130, respectively. The clamping arm 120 is located on the distal side of the clip 130, and the two clamping arms 120 and the two clips 130 are symmetrically arranged on both sides of the base 110. There is a clamping space between the clamping arms 120 and the clips 130 on the same side of the base 110 for accommodating the leaflets. The clamping arms 120 and the clips 130 are both rotatably connected to the base 110 and can rotate relative to the base 110 to change the angle with the axis of the base 110, thereby increasing or decreasing the clamping space. In this way, the mitral valve leaflets (i.e., the anterior leaflet and the posterior leaflet) can be clamped by controlling the relative movement between the clamping arms 120 and the clips 130.

[0045] Specifically, the clamping arm 120 includes a first clamping arm 121 and a second clamping arm 122, which are symmetrically arranged about the axis of the base 110. Preferably, the axis of the base 110 lies within the plane of the motion paths of the first clamping arm 121 and the second clamping arm 122, to better grip the edges of the mitral valve leaflets 300. The "plane of the motion paths of the first clamping arm 121 and the second clamping arm 122" herein refers to the motion paths of the first clamping arm 121 and the second clamping arm 122 when they rotate relative to the base 110. Preferably, the first clamping arm 121 and the second clamping arm 122 are pivotally connected to the base 110 at the same location. In this case, the first clamping arm 121 and the second clamping arm 122 can use the same pivot axis. Accordingly, the clip 130 includes a first clip 131 and a second clip 132, each corresponding to the two clamping arms and located at the proximal end of the corresponding clamping arm.

[0046] The mitral valve clip 100 may further include an actuating assembly 140, which may include a base 141, a first clamp arm link 142, and a second clamp arm link 143. The first clamp arm link 142 has one end pivotally connected to the first clamp arm 121 and the other end pivotally connected to the base 141. The second clamp arm link 143 has one end pivotally connected to the second clamp arm 122 and the other end pivotally connected to the base 141. The base 110 includes an axially extending receiving channel. The base 141 is generally T-shaped. The ends of its transverse arms, which extend perpendicular to the axial direction of the base 110, are pivotally connected to the first clamp arm link 142 and the second clamp arm link 143, respectively. The axially extending straight arm of the base 111 has one end connected to the transverse arm and the other end received in the receiving channel. The straight arm is detachably connected to the drive wire 240 of the delivery device described below and is axially movable relative to the base 110. In this way, the base 110, the base 141, the first clamp arm link 142 and the first clamp arm 121 form a mechanism similar to a connecting rod slider mechanism. Similarly, the base 110, the base 141, the second clamp arm link 143 and the second clamp arm 122 form a mechanism similar to a connecting rod slider mechanism. When the base 110 remains relatively stationary, the drive wire 240 drives the base 141 to move axially relative to the base 110, thereby causing the first clamp arm 121 and the second clamp arm 122 to rotate, thereby achieving clamping of the leaflet edge with the assistance of the first clamp 131 and the second clamp 132. More specifically, when the drive wire moves proximally, the first clamp arm 121 and the second clamp arm 122 rotate and move closer to the base 110. When the drive wire moves distally, the first clamp arm 121 and the second clamp arm 122 rotate and move away from the base 110.

[0047] See also Figure 1 as well as Figure 4 The mitral valve clip 100 passes from the femoral vein to the inferior vena cava and then to the right atrium. After passing through the atrial septum, it enters the left atrium 400 and the left ventricle 500, and then clamps the edges of the mitral valve leaflets 300, thereby reducing mitral regurgitation. To achieve the above purpose, a delivery device is generally used to move the mitral valve clip 100 into the left atrium 400 in a form with the smallest possible profile (at this time, the clamping arms and the base are basically parallel to each other), and then the clamping arms 120 of the mitral valve clip 100 are driven to rotate and unfold, passing through the mitral valve at a suitable angle and entering the left ventricle 500. After the edges of the anterior and posterior leaflets enter the clamping space, the clips 130 are released, and the clamping arms 120 are rotated to narrow the clamping space until the clamping arms 120 and the clips 130 cooperate to clamp the mitral valve leaflets 300.

[0048] Please refer to Figure 5In the existing conveying device, the first movable member 150 drives the rotating shaft 160 of the fixed driving wire 240 to move axially so that the clamping arm 120 moves. The first movable member 150 is provided with a first positioning groove, and the outer wall of the rotating shaft 160 is provided with a second positioning groove. The cross-sectional shape of the first positioning groove and the cross-sectional shape of the second positioning groove are configured to cooperate with each other to form a closed shape, so that the first positioning groove and the second positioning groove after cooperation form a positioning through hole 170. The positioning pin 180 is installed in the positioning through hole 170 so that the first movable member 150 and the rotating shaft 160 are relatively fixed. Only when the first movable member 150 moves, the rotating shaft 160 will follow and move. Thus, due to the effect of the positioning pin 180, the first movable member 150 and the rotating shaft 160 form an integral body.

[0049] The inventors have discovered that after the mitral valve clip 100 is driven and clamps the anterior and posterior lobes of the mitral valve, the clamp arm 120 and the base 110 are at a certain angle, that is, the first moving member 150 still has an excess travel that can allow the clamp arm 120 to move from a certain angle with the base 110 to a position substantially parallel to the base 110. If the operator continues to operate Figure 5 The existing device shown in the figure drives the driving wire 240 to move toward the proximal end through the first movable member 150. The driving wire 240 can still drive the clamping arm 120, and the clamping arm 120 will still apply force to the anterior flap and the posterior flap. At this time, the anterior flap and the posterior flap may be damaged. Particularly when the anterior flap and the posterior flap of the patient are thicker, if the operator continues to operate the driving wire 240 according to habit, even if the operator operates the driving wire 240 to move a less distance, the above situation is likely to occur. On the other hand, because the anterior flap and the posterior flap of the clamped mitral valve are similar to rigid bodies, the clamping arm 120 can not continue to deflect, and the driving wire 240 can not continue to move toward the proximal end as a whole. At this time, the operating force that the driving wire 240 is subjected to can only cause the driving wire 240 to produce deformation, and the free stroke of the first movable member 150 is often greater than the maximum deformation of the driving wire 240. This causes that when the existing device is continued to be operated, it is easy to cause the driving wire 240 to break.

[0050] To solve the above technical problems, an embodiment of the present invention provides a delivery device for delivering a prosthesis having a movable part, comprising: a housing, a drive assembly, comprising a second movable part, the second movable part being movably accommodated in the housing along the axial direction of the housing relative to the housing; a wire fixing member, movably accommodated in the second movable part; a drive wire, the proximal end of the drive wire being fixed to the wire fixing member, and the distal end of the drive wire being used to detachably connect to the prosthesis; the second movable part drives the drive wire to move axially via the wire fixing member to drive the movable part of the prosthesis (in this embodiment, the clamping arm of the above-mentioned mitral valve clip) to move; a buffer member, the buffer member being located between the second movable part and the wire fixing member, and being used to apply pre-tightening forces in opposite directions to the second movable part and the wire fixing member, respectively, so that the second movable part and the wire fixing member have a tendency to move away from each other; a limit assembly, the limit assembly being configured to prevent the wire fixing member from moving toward the proximal end under the action of the pre-tightening force.

[0051] Such an arrangement can prevent the driving wire and the movable part from being damaged during the movement, or the human tissue and other parts of the prosthesis acted upon by the movable part from being damaged. Specifically in this embodiment, the friction between the various components and parts in the mitral valve clip and the conveying device can be ignored. When the second movable part is moved toward the distal end, the clamping arm rotates and unfolds, and the distal end of the driving wire is not subjected to the force of the mitral valve clip. With the cooperation of the buffer and the limiting component, the second movable part and the wire fixing part remain relatively stationary in the axial direction, and the wire fixing part moves toward the distal end with the second movable part; when the second movable part is moved toward the proximal end, and the mitral valve clip clamps the anterior and posterior petals, because the anterior and posterior petals of the mitral valve are in contact with each other before clamping, the mitral valve clip is in contact with each other. The force exerted by the clamping arm can be ignored, and the force exerted on the distal end of the drive wire can be ignored. The second movable member and the wire fixing member remain relatively stationary in the axial direction, and the wire fixing member as a whole moves toward the proximal end with the second movable member. After the second movable member continues to move toward the proximal end, and the mitral valve clip clamps the anterior and posterior valves, as previously described, the clamping arm of the mitral valve clip can no longer continue to rotate, and the drive wire no longer moves toward the proximal end as a whole. Instead, the distal end of the drive wire is approximately fixed, and the proximal end of the drive wire moves toward the proximal end, so the tension of the drive wire gradually increases. When the tension of the drive wire is greater than the preload force, the second movable member begins to move toward the proximal end relative to the wire fixing member, further squeezing the buffer member. In the prior art, the deformation amount of the driving wire is identical with the axial displacement amount of the first moving member. In the present embodiment, when the tension force of the driving wire is greater than the preload force, the wire fixing member is only subjected to the force exerted on the driving wire by the buffer member, and the force exerted by the buffer member by the second moving member is related to the elastic properties of the buffer member itself (for example, the Hooke's coefficient of the elastic member; for another example, the damping coefficient of the hydraulic buffer; for another example, the damping coefficient of the pneumatic buffer) and the axial displacement of the second moving member. Therefore, the force exerted by the wire fixing member by the buffer member increases slowly as the second moving member squeezes the buffer member. Thus, the tension force of the driving wire also increases slowly, which can avoid leaflet damage or driving wire rupture. On the other hand, because the elastic properties of the buffer member itself are generally much smaller than the tensile modulus of the driving wire, the deformation amount produced by the driving wire by the force exerted by the wire fixing member (that is, the transmission of the force exerted by the buffer member to the wire fixing member) is much smaller than the axial displacement amount of the second moving member, and the driving wire is well protected.

[0052] The following is a detailed description of the implementation details of the conveying device of this embodiment. The following content is only provided for ease of understanding and is not necessary for implementing this solution.

[0053] See also Figures 6 to 8An embodiment of the present invention provides a delivery device 200 for use with the aforementioned mitral valve clip 100. The delivery device 200 includes a housing 210, a drive assembly including a second moving member 220, a wire fixing member 230, a buffer member 250 positioned between the second moving member 220 and the wire fixing member 230, a position limiting assembly, and a drive wire 240.

[0054] The second moving member 220 is movably disposed in the housing 210 relative to the housing 210 along the axial direction of the housing 210. The wire fixing member 230 is movably accommodated in the second moving member 220.

[0055] The proximal end of the driving wire 240 is fixed to the wire fixing member 230, and the distal end of the driving wire 240 is used to detachably connect to the mitral valve clip 100. The second moving member 220 drives the driving wire 240 to move axially via the wire fixing member 230 to drive the clip arm 120 of the mitral valve clip 100 to move.

[0056] The buffer member 250 located between the second movable member 220 and the wire fixing member 230 is used to apply preload forces in opposite directions to the second movable member 220 and the wire fixing member 230 respectively, so that the second movable member 220 and the wire fixing member 230 tend to move away from each other.

[0057] The limiting assembly is configured to prevent the wire fixing member 230 from moving toward the proximal end of the second movable member 220 under the action of the preload force. Because the buffer member applies preload forces in opposite directions to the second movable member 220 and the wire fixing member 230, respectively, the second movable member 220 and the wire fixing member 230 tend to move away from each other. However, the presence of the limiting assembly prevents the second movable member 220 and the wire fixing member 230 from moving away from each other, thereby maintaining relative stillness in the axial direction.

[0058] See also Figure 7 and Figure 11 The housing 210 includes a receiving space 211 , and a proximal opening 212 is provided at the proximal end of the housing 210 . The distal end of the second moving member 220 passes through the proximal opening 212 and is received in the receiving space 211 .

[0059] See also Figure 11 and Figure 12, drive assembly also includes a driver 260, and the driver 260 is transmission-connected with the second mobile member 220, so that the operating force of the operator is transmitted to the second mobile member 220, so that the second mobile member 220 moves axially. In one example, the driver 260 is sleeved on the second mobile member 220 peripheries, and the driver 260 is provided with an internal thread 261, and the second mobile member 220 is provided with an external thread 222 that cooperates with the internal thread 261, and the driver 260 and the second mobile member 220 are threadedly connected, and the driver 260 is configured to be rotatable relative to the shell 210, and is axially static relative to the shell 210, and the second mobile member 220 is configured to be movable relative to the shell 210, and is circumferentially static relative to the shell 210. Like this, the operator rotates the driver 260, and the driver 260 drives the second mobile member 220 to move axially.

[0060] Specifically, the driving member 260 comprises a connecting passage 262 that runs through the front and rear end surfaces, the inwall of the connecting passage 262 is provided with an internal thread 261, a part of the outer wall of the second moving member 220 is provided with an external thread 222, and after the far-end of the second moving member 220 passes through the connecting passage 262, the external thread 222 and the internal thread 261 cooperate with each other. Like this, the second moving member 220 and the driving member 260 constitute a screw slider transmission mechanism, and when the rotating driving member 260, the second moving member 220 can move axially relative to the shell 210. It is understandable that a stroke limit is provided at the far-end of the external thread 222 to prevent the moving stroke of the second moving member 220 from exceeding the limit.

[0061] See again Figure 11 and Figure 12 The edge of the proximal opening 212 is radially retracted to form an opening shoulder 213. The distal end of the driving member 260 is provided with a circumferentially extending limiting groove 263. The opening shoulder 213 is accommodated in the limiting groove 263 so that the driving member 260 is restricted and can only rotate relative to the housing 210.

[0062] The second moving member 220 can be moved relative to the shell 210 along the axial direction of the shell 210, and is circumferentially static relative to the shell 210. For example, the inwall of the shell 210 is provided with the first limiting member (not shown), and the outer surface of the second moving member 220 distal ends is provided with the second limiting member (not shown), and the first limiting member is configured to limit the second limiting member circumferentially, so that the second moving member 220 can only be axially moved relative to the shell 210. Exemplary, the inside of the shell 210 can be provided with one or more axially extending chute, and promptly the first limiting member is a chute, and the distal outer surface of the second moving member 220 is provided with a protruding structure, and promptly the second limiting member is a protruding structure. The protruding structure can be accommodated in the chute, and the protruding structure can move in the direction that the chute constrains. During the rotation drive member 260, the sidewall of the chute stopped the protruding structure from rotating, thereby made the second moving member 220 can't rotate circumferentially.

[0063] See again Figure 8 , the second movable member 220 is provided with a movable channel 221 in the axial direction. The distal end of the wire fixing member 230 is at least partially movably accommodated in the movable channel 221. On the whole, the outer diameter of the wire fixing member 230 is less than or equal to the diameter of the movable channel 221. In this way, the wire fixing member 230 can move axially relative to the second movable member 220. In one example, the movable channel 221 includes a first sub-channel 221a and a second sub-channel 221b, and the first sub-channel 221a is located at the distal end side of the second sub-channel 221b, and the inner diameter of the first sub-channel 221a is less than the inner diameter of the second sub-channel 221b, so as to form a first abutting surface 221c at the junction of the first sub-channel 221a and the second sub-channel 221b. In this way, a step structure can be formed at the junction of the first sub-channel 221a and the second sub-channel 221b. Since the first sub-channel 221a is located at the distal end side of the second sub-channel 221b, the step surface of the step structure is towards the proximal end, forming the first abutting surface 221c. Exemplarily, the movable channel 221 axially extends through the second movable member 220, and the first sub-channel 221a and the second sub-channel 221b are both circular channels, with the inner diameter of the first sub-channel 221a being smaller than the inner diameter of the second sub-channel 221b. Furthermore, the movable channel 221 may also be an elliptical channel, a polygonal channel, or the like, and the shape of the wire fixture 230 may be appropriately adjusted to match the movable channel 221.

[0064] See also Figure 9 Accordingly, the wire fixture 230 includes a first section 231 located at the distal end and a second section 232 located at the proximal end. The outer diameter of the first section 231 is smaller than the outer diameter of the second section 232, so as to form a second abutment surface 233 at the connection between the first section 231 and the second section 232. In this way, a stepped structure can be formed at the connection between the first section 231 and the second section 232. Since the first section 231 is located on the distal side of the second section 232, the stepped surface of the stepped structure faces the distal end, forming the second abutment surface 233. Exemplarily, the first section 231 and the second section 232 are both cylindrical structures, and the outer diameter of the first section 231 is smaller than the outer diameter of the second section 232.

[0065] Further, the outer diameter of the first section 231 can be equal to or slightly smaller than the inner diameter of the first sub-channel 221a, and the outer diameter of the second section 232 can be equal to or slightly smaller than the inner diameter of the second sub-channel 221b, that is, the first section 231 can be accommodated in the first sub-channel 221a and the second sub-channel 221b, but the second section 232 part can only be accommodated in the second sub-channel 221b. In this way, the silk fixing member 230 can move axially relative to the second movable member 220. When the first section 231 is located in the first sub-channel 221a, and the second section 232 is located in the second sub-channel 221b, the second abutting surface 233 is located in the second sub-channel 221b and is relative to the first abutting surface 221c. At this time, the buffer member 250 is disposed between the first abutting surface 221c and the second abutting surface 233. When the second movable member 220 and the wire fixing member 230 move toward each other and compress the buffer member 250, the buffer member 250 generates a force on the second movable member 220 and the wire fixing member 230. At this time, the buffer member 250 is located in the second sub-channel 221b.

[0066] In an alternative example, mobile channel 221 is no longer provided with first sub-channel 221a and second sub-channel 221b, using the proximal end face of second moving member 220 as abutment surface, i.e. the 3rd abutment surface.At this moment, mobile channel 221 internal diameters are constant or continuously change.Perhaps, although mobile channel 221 is provided with first sub-channel 221a and second sub-channel 221b, and the first abutment surface 221c that first sub-channel 221a and second sub-channel 221b form, first abutment surface 221c is no longer used for abutting described buffer member 250. The wire fixing member 230 still includes a first section and a second section, wherein the outer diameter of the first section is smaller than the outer diameter of the second section, so as to form a second abutment surface 233 at the connection between the first section and the second section, the outer diameter of the first section 231 of the wire fixing member 230 is equal to or slightly smaller than the inner diameter of the movable channel 221, and the first section 231 is partially located in the movable channel 221, and the outer diameter of the second section 232 is larger than the outer diameter of at least the proximal end of the movable channel 221, so that the second section 232 is located on the proximal side of the second movable member 220 and is limited to the outside of the movable channel 221. The buffer member 250 is located between the third abutment surface 233 and the second abutment surface 233, and can abut the third abutment surface 233. At this time, the buffer member 250 is located outside the movable channel 221. This embodiment has no particular restrictions on the specific structure of the limiting assembly.

[0067] See also Figure 6 、 Figure 7 and Figure 9In one example, the limiting assembly includes a snap-fit ​​cover 270 and a limiting member 223. The limiting member 223 is disposed at the proximal end of the second movable member 220. The snap-fit ​​cover 270 abuts the proximal end of the wire fixing member 230 and is coupled to the limiting member 223 so that the second movable member 220 and the wire fixing member 230 remain relatively stationary in the axial direction under the action of the preload force. For example, the snap-fit ​​cover 270 can be movably sleeved on the proximal end of the second movable member 220 and is coupled to the limiting member 223 so that the second movable member 220 and the wire fixing member 230 remain relatively stationary in the axial direction under the action of the preload force.

[0068] In one example, the snap-on cover 270 comprises an abutment 271 and a first limiting portion 272 that are fixedly connected to each other. The abutment 271 is arranged on the proximal end of the first limiting portion 272, for abutting the proximal end of the silk fixture 230, and the first limiting portion 272 is used for coupling with limiting member 223. Like this, the silk fixture 230 is restricted to move to the proximal end relative to the second moving member 220 under the preload force. Exemplary, the first limiting portion 272 and limiting member 223 can be limited by the mode of clamping. Perhaps, the first limiting portion 272 and limiting member 223 also can adopt other connection modes, and the silk fixture 230 is restricted to move to the proximal end relative to the second moving member 220 under the preload force.

[0069] When assembling the second movable member 220, the wire fixing member 230, the buckling cover 270, the limiting member 223 and the buffer member 250, the buffer member 250 is first placed in the second sub-channel 221b, and the distal end of the buffer member 250 contacts the first abutting surface 221c; then the wire fixing member 230 is placed in the movable channel 221, and the proximal end of the buffer member 250 contacts the second abutting surface 233. In the natural state, the buffer member 250 maintains a natural length, and the proximal end of the wire fixing member 230 extends from the proximal end of the second movable member 220; the buckling cover 270 is made to abut and squeeze the proximal end of the wire fixing member 230, so that the wire fixing member 230 squeezes the buffer member 250 through the second abutting surface 233, and the buffer member 250 is compressed to generate a pre-tightening force until the buckling cover 270 is coupled with the limiting member 223. In this way, the buffer member 250 can be configured to be compressed until the pre-tightening force reaches a predetermined threshold value. At this time, due to the action of the buffer member 250 on the wire fixing member 230, the wire fixing member 230 has a tendency to move toward the proximal end of the second movable member 220. At the same time, due to the cooperation of the snap-fit ​​cover 270 and the limiting member 223, the wire fixing member 230 is restricted from moving toward the proximal end of the second movable member 220, so that the wire fixing member 230 and the second movable member 220 remain relatively stationary axially.

[0070] Taking the mutual clamping of the first limiting portion 272 and the limiting member 223 as an example, the snap-fit ​​cover 270 also includes a connecting portion 273 connecting the abutment portion 271 and the first limiting portion 272, and the connecting portion 273 is arranged circumferentially along the abutment portion 271 and extends axially. The first limiting portion 272 is positioned at an end of the connecting portion 273 away from the abutment portion 271. In one example, the first limiting portion 272 is a first projection extending radially toward the second moving member 220 (inwardly in the figure). Accordingly, the limiting member 223 is a second projection extending radially away from the direction (outwardly in the figure) of the second moving member 220, and the first projection is clamped with the second projection so that the silk fixing member 230 and the second moving member 220 remain axially relatively static." radially " is perpendicular to the axial direction.

[0071] See again Figure 10 The cooperation of the connecting portion 273 and the abutting portion 271 makes the snap-fit ​​cover 270 as a whole groove-shaped, which includes a cavity 274, and the cavity 274 is used to accommodate the proximal end of the second movable member 220 and the proximal end of the wire fixing member 230. The abutting portion 271 is the bottom of the groove, and the connecting portion 273 is the side wall of the groove. The first protrusion is arranged at one end of the connecting portion 273 away from the abutting portion 271. It can be understood that the circumferential size of the cavity 274 should be larger than the outer diameter of the proximal end of the second movable member 220 and larger than the outer diameter of the proximal end of the wire fixing member 230; the axial size of the cavity 274 will affect the compressed size of the buffer member 250, that is, the size of the preload. Therefore, the axial size of the cavity 274, as a factor affecting the preload, will be adjusted according to the size of the preload as needed.

[0072] In one example, the connecting portion 273 is cylindrical, and the first protrusions may be multiple and spaced apart along the circumference of the connecting portion 273. Alternatively, the first protrusion may be one and extends along the circumference of the connecting portion 273.

[0073] In one example, the connecting portion 273 can be set to a plurality of and arranged at circumferential intervals around the abutting portion 271. At the same time, each connecting portion 273 extends axially. At this time, the first limiting portion 272 is correspondingly set to a plurality of and is arranged one-to-one at the far end of the first limiting portion 272 away from the abutting portion 271. For example, the connecting portion 273 is circumferentially set to a plurality of comb tooth structures. With such a configuration, when the second movable member 220 and the wire fixing member 230 are connected using the snap-fit ​​cover 270, each connecting portion 273 can better achieve elastic deformation, thereby reducing the difficulty of assembly.

[0074] Continue to see Figure 8 and Figure 10The first projection includes a first sliding surface 272a and a fourth abutting surface 272b, wherein the first sliding surface 272a is located at the distal end side of the fourth abutting surface 272b. The second projection includes a second sliding surface 223a and a fifth abutting surface 223b, wherein the second sliding surface 223a is located at the proximal end side of the fifth abutting surface 223b. For example, the first sliding surface 272a can be tilted, with the first sliding surface 272a gradually approaching the second moving member 220 from far to near, and the fourth abutting surface 272b being perpendicular to the axial direction or tilted in the same direction as the first sliding surface 272a; the second sliding surface 223a can be tilted, with the second sliding surface 223a gradually moving away from the direction of the second moving member 220 from far to near, and the fifth abutting surface 223b being perpendicular to the axial direction or tilted in the same direction as the second sliding surface 223a. Preferably, the fourth abutting surface 272b and the fifth abutting surface 223b have the same degree of inclination.

[0075] When the snap-fit ​​cover 270 is engaged with the stopper 223, the first sliding surface 272a can slide relative to the second sliding surface 223a until the fourth abutting surface 272b moves to the side of the fifth abutting surface 223b. Furthermore, after the snap-fit ​​cover 270 is engaged with the stopper 223, the fourth abutting surface 272b is configured to abut the fifth abutting surface 223b. This arrangement allows the first sliding surface 272a and the second sliding surface 223a to cooperate with each other, and the fourth abutting surface 272b and the fifth abutting surface 223b to cooperate with each other, achieving the snap-fit ​​connection between the snap-fit ​​cover 270 and the stopper 223, reducing assembly difficulty.

[0076] Optionally, in the cross section along the axial direction, the cross-sectional shape of the first protrusion can be a triangle or a trapezoid, and the cross-sectional shape of the second protrusion can also be a triangle or a trapezoid. Preferably, the first protrusion and the second protrusion are both right triangles or right trapezoids.

[0077] refer to Figure 13 In another alternative embodiment, the limiting assembly includes a slide groove 224 arranged at the proximal end of the second movable member 220 and extending axially, and a sliding portion 234 arranged at the proximal end of the wire fixing member 230, and the sliding portion 234 is movably arranged in the slide groove 224.

[0078] In one example, sliding portion 234 can be arranged on the second section 232 side of the silk fixture 230, and chute 224 is arranged on the sidewall of the second sub-channel 221b of the second mobile member 220. Under the preload effect, there is a movement trend away from each other between the second mobile member 220 and the silk fixture 230, because sliding portion 234 abuts the proximal sidewall of chute 224, so that the second mobile member 220 and the silk fixture 230 keep axial relative static. When driving wire 240 tension forces greater than preload, if the operator continues to operate driver 260, the second mobile member 220 can move relative to the silk fixture 230. At this moment, sliding portion 234 then moves to the far end relative to chute 224. The application is not restricted to the quantity and specific shape of chute 224, sliding portion 234.

[0079] For example, there are multiple slide grooves 224 that are spaced apart along the circumference of the second movable member 220 ; there are multiple sliding portions 234 that are spaced apart along the circumference of the wire fixing member 230 ; at least part of the slide grooves 224 accommodates at least one sliding portion 234 .

[0080] In another alternative embodiment, similar to the above embodiment, the difference is that the limiting assembly includes a second limiting portion provided on the second moving member 220 and a third limiting portion provided on the wire fixing member 230, and a buffer member 250 is located between the second moving member 220 and the third limiting portion. The buffer member 250 is used to apply a preload force to the second moving member 220 and to apply a preload force to the wire fixing member 230 through the second limiting portion. The two preload forces are of the same magnitude but in opposite directions. Furthermore, the second limiting portion and the third limiting portion cooperate with each other to prevent the wire fixing member 230 from moving toward the proximal end under the action of the preload force it receives.

[0081] In one example, the second limiting portion can adopt the above-mentioned slide groove 224, and the third limiting portion can adopt the above-mentioned sliding portion 234. Further, in this example, the wire fixing member 230 may no longer be provided with the first section 231 and the second section 232, and there is no second abutting surface. That is, the size of the wire fixing member 230 remains unchanged or changes continuously, for example, it is approximately cylindrical or truncated cone-shaped. Alternatively, although the second abutting surface is formed between the first section 231 and the second section 232 in the wire fixing member 230, the second abutting surface is no longer used to abut the buffer member 250. The buffer member 250 is located between the first abutting surface 221c in the second moving member 220 and the distal end face of the sliding portion 234.

[0082] In this embodiment, the proximal end of the drive wire 240 is fixed to the wire fixture 230, and the distal end, after passing through the accommodation space 211, exits the housing 210 and extends toward the distal end of the delivery device 200, where it is removably connected to the mitral valve clip 100. It should be noted that the drive wire 240 can preferably be made of a biocompatible metal wire, such as stainless steel, nickel-titanium, or the like. Furthermore, the distal end of the drive wire 240 can be provided with an external thread, and the proximal end of the base 141 can be provided with an internal thread that mates with the external thread, thereby removably connecting the drive wire 240 and the base 141 via the threaded connection. Alternatively, the distal end of the drive wire 240 can be provided with an internal thread, and the proximal end of the base 141 can be provided with an external thread that mates with the internal thread, thereby threading the drive wire 240 and the base 141 together. Alternatively, the distal end of the drive wire 240 can be provided with another coupling structure, and the proximal end of the base 141 can be provided with a structure that mates with the coupling structure to facilitate connection and separation with the base 141.

[0083] This embodiment does not particularly limit the specific type of the buffer 250, as long as it can generate a force when under pressure. For example, the buffer 250 can be an elastic member, a hydraulic buffer, or a pneumatic buffer. Exemplarily, in a natural state, the buffer 250 drives the proximal end of the wire fixing member 230 to extend from the proximal end of the second movable member 220. When the snap-fit ​​cover 270 abuts the wire fixing member 230, it drives the wire fixing member 230 to move toward the distal end. At the same time, the buffer 250 is subjected to a force to generate a preload. Under the action of the preload, the second movable member 220 and the wire fixing member 230 have a tendency to move away from each other; when the snap-fit ​​cover 270 is coupled to the first limit portion 272, the second movable member 220 and the wire fixing member 230 are kept axially relative to each other. Preferably, the buffer 250 is configured as an elastic member, such as a rubber ring, a compression spring, etc. The elastic member as the buffer 250 can be directly mounted on the wire fixing member 230. In this way, the buffer 250 has a simple structure and is easy to assemble.

[0084] See again Figure 6 and Figure 7 The delivery device further includes a catheter 280 extending from the housing 210 to the distal end of the delivery device. The catheter 280 is detachably connected to the base 110 of the mitral valve clip 100. The specific manner of detachable connection between the two is not particularly limited in this embodiment. The catheter 280 also has an axially extending delivery channel for the drive wire 240 to pass through.

[0085] The above is a detailed introduction to the conveying device provided by the embodiment of the present invention. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above implementation methods is only used to help understand the ideas of the present invention. There may be changes in the specific implementation methods and application scope. In summary, the contents of this specification should not be understood as limiting the present invention.

Claims

1. A conveying device for conveying a prosthesis having movable parts, characterized in that: include: shell; A driving assembly including a moving member, wherein the moving member is accommodated in the housing so as to be movable relative to the housing along an axial direction of the housing; a wire fixing member, the wire fixing member being movably accommodated in the moving member; a driving wire, wherein the proximal end of the driving wire is fixed to the wire fixing member, and the distal end of the driving wire is used to be detachably connected to the prosthesis; the moving member drives the driving wire to move axially via the wire fixing member to drive the movable member to move; a buffer member, the buffer member being located between the moving member and the wire fixing member and being used to apply pre-tightening forces in opposite directions to the moving member and the wire fixing member, respectively, so that the moving member and the wire fixing member tend to move away from each other; A limiting assembly is configured to prevent the wire fixing component from moving toward the proximal end under the action of the pre-tightening force.

2. The conveying device according to claim 1, characterized in that The moving member includes an axially extending moving channel, the moving channel including a first sub-channel and a second sub-channel, the first sub-channel is located on a distal side of the second sub-channel, and the inner diameter of the first sub-channel is smaller than the inner diameter of the second sub-channel, so as to form a first abutment surface at the connection between the first sub-channel and the second sub-channel; The wire fixing member includes a first section and a second section, the outer diameter of the first section is smaller than the outer diameter of the second section, so as to form a second abutment surface at the connection between the first section and the second section, the first section is partially accommodated in the first sub-channel, the second section is partially accommodated in the second sub-channel, and the buffer member is located between the first abutment surface and the second abutment surface.

3. The conveying device according to claim 1, characterized in that The moving member includes an axially extending moving channel, the end face of the proximal end of the moving member is defined as a first abutment surface, the wire fixing member includes a first section and a second section, the outer diameter of the first section is smaller than the outer diameter of the second section, so as to form a second abutment surface at the connection between the first section and the second section, the first section is partially accommodated in the moving channel, the second section is located on the proximal side of the moving member and is limited to outside the moving channel; the buffer member is located between the first abutment surface and the second abutment surface.

4. The conveying device according to claim 1 or 2, characterized in that The limiting assembly includes a slide groove provided at the proximal end of the moving member and extending axially, and a sliding portion provided at the proximal end of the wire fixing member, wherein the sliding portion is movably provided in the slide groove to couple the moving member and the fixing member.

5. The conveying device according to claim 4, characterized in that There are multiple chute grooves, which are spaced apart along the circumference of the movable member; there are multiple sliding parts, which are spaced apart along the circumference of the fixed member; at least one sliding part is accommodated in at least part of the chute grooves.

6. The conveying device according to any one of claims 1 to 3, characterized in that: The limiting assembly includes a snap-fit ​​cover and a limiting member arranged at the proximal end of the moving member. The snap-fit ​​cover abuts the proximal end of the wire fixing member and couples the limiting member to keep the moving member and the wire fixing member axially relatively stationary under the action of the preload force.

7. The conveying device according to claim 6, characterized in that The snap-on cover includes an abutting portion and a limiting portion that are fixedly connected. The abutting portion is arranged at the proximal end of the limiting portion and is used to abut the proximal end of the wire fixing member. The limiting portion is used to couple with the limiting member.

8. The conveying device according to claim 7, characterized in that The snap-on cover also includes a connecting portion fixedly connecting the abutting portion and the limiting portion, wherein the connecting portion is arranged circumferentially along the abutting portion and extends axially; the limiting portion is located at one end of the connecting portion away from the abutting portion, and the limiting portion is used to engage with the limiting member.

9. The conveying device according to claim 8, characterized in that The limiting portion is a first protrusion extending radially toward the moving member, and the limiting member is a second protrusion arranged along the circumference of the moving member and extending radially toward the snap-fit ​​cover, the first protrusion includes a first sliding surface and a third abutting surface, and the first sliding surface is located on the distal side of the third abutting surface; the second protrusion includes a second sliding surface and a fourth abutting surface, and the second sliding surface is located on the proximal side of the fourth abutting surface; The first sliding surface is configured to slide relative to the second sliding surface when the snap-fit ​​cover is engaged with the limiter; the third abutting surface is configured to abut against the fourth abutting surface after the snap-fit ​​cover is engaged with the limiter.

10. The conveying device according to any one of claims 1 to 3, characterized in that: The buffer member is an elastic member, a hydraulic buffer or a pneumatic buffer.

11. The conveying device according to claim 10, characterized in that The elastic member is a compression spring or a rubber ring sleeved on the wire fixing member.

12. A conveying device for conveying a prosthesis having movable parts, characterized in that: include: shell; A driving assembly including a moving member, wherein the moving member is accommodated in the housing so as to be movable relative to the housing along an axial direction of the housing; a wire fixing member, the wire fixing member being movably accommodated in the moving member; a driving wire, wherein the proximal end of the driving wire is fixed to the wire fixing member, and the distal end of the driving wire is used to be detachably connected to the prosthesis; the moving member drives the driving wire to move axially via the wire fixing member to drive the movable member to move; A limiting assembly, comprising a first limiting portion provided on the moving member and a second limiting portion provided on the wire fixing member; a buffer member, the buffer member being located between the movable member and the second limiting portion, the buffer member being configured to apply a first pre-tightening force to the movable member and a second pre-tightening force to the wire fixing member via the second limiting portion, so that the movable member and the wire fixing member tend to move away from each other, the first pre-tightening force and the second pre-tightening force being equal in magnitude and opposite in direction; The limiting assembly is configured to prevent the wire fixing piece from moving toward the proximal end under the action of the second pre-tightening force through the cooperation of the first limiting portion and the second limiting portion.

13. The conveying device according to claim 12, characterized in that The first limiting portion is a sliding groove provided at the proximal end of the movable member and extending axially. The second limiting portion is a sliding portion provided at the proximal end of the wire fixing member. The sliding portion is movably provided in the sliding groove.

14. The conveying device according to claim 13, characterized in that The moving member includes an axially extending moving channel, the moving channel including a first sub-channel and a second sub-channel, the first sub-channel is located on a distal side of the second sub-channel, and the inner diameter of the first sub-channel is smaller than the inner diameter of the second sub-channel, so as to form a first abutment surface at the connection between the first sub-channel and the second sub-channel; The wire fixing member is accommodated in the moving channel, and the buffer member is located between the first abutting surface and the distal end surface of the sliding portion.

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