Tumor electric field treatment system, electrode sheet, tumor treatment device and method

Abstract

The application provides a tumor electric field treatment system, an electrode sheet, a tumor treatment device and a method. The system comprises at least one pair of electrode sheets. A plurality of electrode units of each electrode sheet is divided into a plurality of row groups and a plurality of column groups. The ground terminals of temperature detection units in each column group are connected to a ground pin through a control switch. The temperature detection units in each row group are connected in series. After the signal terminals of the temperature detection units are short-circuited with corresponding electrode units, the signal terminals are connected to a switching unit through a two-purpose signal line. When the two-purpose signal line is connected to a temperature sampling point, the switching state of the control switch is configured to make the temperature detection signals of one or more combinations of the temperature detection units in the electrode sheet be sampled. When the two-purpose signal line is connected to an alternating power line, the electrode units of at least one row group are applied with alternating electric signals based on the alternating power line. In this way, a plurality of electrode units are controlled in zones by using fewer conductive traces.

Description

Technical Field

[0001] The present application relates to tumor electric field therapy technology, and in particular to a tumor electric field therapy system, an electrode sheet, a tumor treatment device and a method. Background Art

[0002] Tumor electric field therapy is a method that uses low-intensity, medium-high frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis in mitotic cells, thereby achieving the effect of treating tumors.

[0003] Compared with traditional cancer treatment methods, tumor electric field therapy has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometric shape and high-frequency mitosis, make them susceptible to tumor electric field therapy. Tumor electric field therapy disrupts the normal aggregation of microtubules by exerting directional forces on polar particles (such as macromolecules and organelles) in cells. These processes may lead to physical damage to the cell membrane and cell apoptosis. At the end of cell mitosis, the structural morphology of the cleavage furrow will lead to uneven distribution of the electric field around it. At the same time, under the influence of tumor electric field therapy, the electric field intensity at the cleavage furrow is significantly enhanced, and the charged substances in the cell move toward the cleavage furrow, which interferes with or even destroys the formation of the cell structure, and ultimately leads to cell division failure and apoptosis.

[0004] Related art tumor therapy systems use an electric field application device to transmit alternating electrical signals for tumor therapy to electrodes, which then apply an alternating electric field to the patient's tumor site. When the tumor therapy electric field is applied to the patient's body, it accumulates heat at the application site, causing the temperature to rise accordingly. Therefore, the temperature at the application site must be monitored. If the temperature is too high, the electric field intensity must be adjusted promptly to reduce the risk of skin burns caused by excessive heat.

[0005] The tumor electric field therapy system includes at least one pair of electrode sheets, each of which contains multiple electrode units. Even if the same alternating electrical signal is applied to each electrode unit, the heat generated by each electrode unit will be different due to its different position, that is, the temperature of each electrode unit on the entire electrode sheet will not be completely consistent. In this way, it is possible that the temperature of some electrode units in the entire electrode sheet exceeds the preset temperature, while the temperature of other electrode units is normal. In order to improve the effect of tumor electric field therapy, it is necessary to implement individual control of the over-temperature electrode units. However, for the electrode sheets in the related art, implementing individual control of the electrode units requires setting a conductive trace for each electrode unit in the substrate of the electrode sheet. This will increase the number of conductive traces in the electrode sheet substrate, making the electrode sheet less likely to bend, and the cable electrically connected to the electrode sheet will also be thickened, which increases the overall weight of the electrode sheet, which is not conducive to the application of the electrode sheet. Summary of the Invention

[0006] The present application aims to at least partially address one of the technical problems in the related art. To this end, the first objective of the present application is to provide a tumor therapy field system that utilizes fewer conductive traces to control multiple electrode units in a zoned manner, thereby improving the effectiveness of tumor therapy field therapy and facilitating the application of electrode patches.

[0007] The second objective of this application is to provide an electrode sheet.

[0008] The third object of this application is to provide another tumor electric field treatment system.

[0009] The fourth objective of this application is to provide a tumor treatment device.

[0010] The fifth objective of this application is to provide a method for detecting electrode temperature.

[0011] The sixth objective of this application is to provide a method for detecting electrode abnormalities.

[0012] The seventh objective of this application is to provide a control method for a tumor electric field therapy system.

[0013] The eighth objective of this application is to provide a method for identifying electrode types.

[0014] A ninth objective of the present application is to provide a computer-readable storage medium.

[0015] The tenth objective of this application is to provide an adapter for tumor electric field therapy.

[0016] The eleventh objective of this application is to provide an electric field generator for tumor electric field therapy.

[0017] To achieve the above-mentioned purpose, the first embodiment of the present application provides a tumor electric field therapy system, comprising: at least one pair of electrode sheets, each of the electrode sheets comprising a plurality of electrode units and a plurality of temperature detection units, each of the electrode units being capable of applying an alternating electrical signal, each of the temperature detection units being arranged corresponding to an electrode unit to detect the temperature at the corresponding electrode unit, wherein the plurality of electrode units are configured into at least two row groups and at least two column groups, the grounding terminals of the temperature detection units in each of the column groups being connected to a grounding pin through a control switch, the temperature detection units in each of the row groups being connected in series, and the signal of each temperature detection unit being connected to a grounding pin through a control switch. After the signal terminals are short-circuited with the corresponding electrode units respectively, they are connected to the switching unit through a dual-purpose signal line; the switching unit is configured to switch the dual-purpose signal line to the temperature sampling point or the alternating power line corresponding to the switching unit, so that when the dual-purpose signal line is connected to the temperature sampling point, the temperature detection signals of one or more combinations of all temperature detection units are sampled based on the temperature sampling point by configuring the switching state of the control switch; when the dual-purpose signal line is connected to the alternating power line, the alternating electrical signal is applied to at least one electrode unit of the row group based on the alternating power line.

[0018] According to the tumor electric field therapy system of the embodiment of the present application, for each electrode sheet, multiple electrode units are divided into multiple row groups and multiple column groups, and the ground ends of the temperature detection units corresponding to the electrode units in each column group are commonly connected to the ground pin through a control switch, the temperature detection units corresponding to the electrode units in each row group are connected in series, and the signal ends of the temperature detection units are respectively short-circuited with the corresponding electrode units and then commonly connected to the switching unit through a dual-purpose signal line; at the same time, the switching unit is configured to switch the dual-purpose signal line to connect to the temperature sampling point or the alternating power line corresponding to the switching unit, so that when the dual-purpose signal line is connected to the temperature sampling point, the temperature detection signals of one or more combinations of all temperature detection units are sampled based on the temperature sampling point by configuring the switching state of the control switch, and when the dual-purpose signal line is connected to the alternating power line, the electrode units of at least one row group are applied with an alternating electric signal based on the alternating power line. In this way, temperature sampling and application of alternating electrical signals can be achieved through the dual-purpose signal line. Not only is no new AC signal line (i.e., AC line) added, but the original AC signal line is also eliminated. Therefore, multiple electrode units can be partitioned and controlled using fewer conductive traces, which not only improves the effect of tumor electric field therapy, but also facilitates the application of electrode sheets.

[0019] Furthermore, the switching unit includes at least two bidirectional switches, the first end of each bidirectional switch is connected to the dual-purpose signal line corresponding to each row group, the second end of each bidirectional switch is also connected to the alternating power line, and the third end of each bidirectional switch is connected as a temperature sampling point of the corresponding row group.

[0020] Furthermore, the switching unit is further configured to switch the dual-purpose signal line corresponding to each row group to be connected to the alternating power line, so that the electrode units of each row group are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0021] Furthermore, the switching unit is further configured to switch the dual-purpose signal lines corresponding to at least two of the row groups to be connected to the alternating power line at the same time, so that the electrode units of at least two of the row groups are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0022] Furthermore, the intensity of the alternating electrical signal output by the alternating power line is adjustable.

[0023] Furthermore, the switching unit includes at least two bidirectional switches, the first end of each bidirectional switch is connected to the dual-purpose signal line corresponding to each row group, the second end of each bidirectional switch is connected to a different alternating power line, and the third end of each bidirectional switch serves as a temperature sampling point of the corresponding row group.

[0024] Furthermore, the switching unit is further configured to switch the dual-purpose signal lines corresponding to the at least two row groups to connect to different alternating power lines, so that the alternating electrical signals are applied to the electrode units of each row group based on different alternating power lines.

[0025] Furthermore, the intensities of the alternating electrical signals output by different alternating power lines are adjustable.

[0026] Furthermore, the tumor electric field therapy system also includes a plurality of diodes, each of which is provided corresponding to a temperature detection unit, wherein the anode of each diode is connected to the ground terminal of the corresponding temperature detection unit, and the cathodes of the diodes corresponding to each column group are connected together and then connected to the ground pin through the corresponding control switch.

[0027] Furthermore, each of the temperature sampling points is connected to a DC power supply via a corresponding voltage-dividing resistor.

[0028] Furthermore, an adapter is included, wherein the control switch, the switching unit and the voltage dividing resistor are respectively arranged in the adapter.

[0029] Furthermore, the adapter includes a first controller and an ADC unit, the ADC unit is connected to each of the temperature sampling points to sample the temperature detection signal through each of the temperature sampling points, and the first controller is connected to the ADC unit to determine the temperature at the corresponding electrode unit based on the digital temperature signal output by the ADC unit.

[0030] Furthermore, the first controller is also configured to configure the switch state of the control switch.

[0031] Furthermore, the first controller is also configured to configure the switching state of the bidirectional switch in the switching unit.

[0032] Furthermore, it also includes an electric field generator, which is configured to output the alternating electric signal through the alternating power line.

[0033] Furthermore, the electric field generator includes a second controller and an AC signal generator, the second controller is connected to the AC signal generator, and the second controller is configured to control the AC signal generator to adjust the intensity of the alternating electric signal output by the alternating power line.

[0034] Furthermore, the electric field generator is further configured to obtain the temperature at each electrode unit and control the AC signal generator according to the temperature at each electrode unit.

[0035] Furthermore, the electric field generator also includes a power switch, which is arranged between the AC signal generator and the switching unit. Under the configuration of the second controller, the power switch controls whether the AC signal generator outputs the alternating electric signal through the alternating power line.

[0036] Furthermore, the second controller is also configured to configure the switch state of the control switch.

[0037] Furthermore, the second controller is also configured to configure the switching state of the bidirectional switch in the switching unit.

[0038] To achieve the above-mentioned purpose, the second embodiment of the present application provides an electrode sheet for use in a tumor electric field therapy system, wherein the tumor electric field therapy system includes a switching unit, and the electrode sheet includes: a substrate; a plurality of electrode units and a plurality of temperature detection units arranged on the substrate, each of the electrode units being capable of applying an alternating electrical signal, and each of the temperature detection units being arranged corresponding to an electrode unit to detect the temperature at the corresponding electrode unit, wherein the plurality of electrode units are configured into at least two row groups and at least two column groups; the ground terminals of the temperature detection units in each of the column groups are connected to a ground pin in common through a control switch; the temperature detection units in each of the row groups are connected in series The temperature detection units are connected, and after the signal ends of the temperature detection units are short-circuited with the corresponding electrode units respectively, they are connected to the switching unit through a dual-purpose signal line, so that the dual-purpose signal line is switched by the switching unit to be connected to the temperature sampling point or the alternating power line corresponding to the switching unit; when the dual-purpose signal line is connected to the temperature sampling point, the switching state of the control switch is configured so that the temperature detection signals of one or more combinations of all the temperature detection units are sampled based on the temperature sampling point; when the dual-purpose signal line is connected to the alternating power line, the alternating electrical signal is applied to at least one electrode unit of the row group based on the alternating power line.

[0039] Furthermore, in a case where the dual-purpose signal lines corresponding to each row group are respectively connected to the alternating power line, the electrode units of each row group are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0040] Furthermore, when the dual-purpose signal lines corresponding to at least two of the row groups are simultaneously connected to the alternating power line, the electrode units of at least two of the row groups are simultaneously applied with the alternating electrical signal based on the alternating power line.

[0041] Furthermore, the intensity of the alternating electrical signal output by the alternating power line is adjustable.

[0042] Furthermore, in a case where the dual-purpose signal lines corresponding to the at least two row groups are connected to different alternating power lines, the alternating electrical signals are applied to the electrode units of each row group based on different alternating power lines.

[0043] Furthermore, the intensities of the alternating electrical signals output by different alternating power lines are adjustable.

[0044] Furthermore, the electrode sheet also includes a plurality of diodes, each of which is provided corresponding to a temperature detection unit, wherein the anode of each diode is connected to the ground end of the corresponding temperature detection unit, and the cathodes of the diodes corresponding to each column group are connected together and then connected to the ground pin through the corresponding control switch.

[0045] Furthermore, each of the temperature sampling points is connected to a DC power supply via a corresponding voltage-dividing resistor.

[0046] Furthermore, each of the electrode units is provided with a through-hole, and the through-hole is suitable for accommodating the temperature detection unit.

[0047] Furthermore, the plurality of electrode units and the plurality of temperature detection units are arranged in a substantially array in terms of spatial arrangement, and are arranged in a plurality of rows and columns in terms of circuit connection.

[0048] Furthermore, the number of the plurality of electrode units and the number of the plurality of temperature detection units are both 20, and they are arranged in four rows and five columns in terms of circuit connection.

[0049] To achieve the above-mentioned purpose, the third aspect of the present application provides a tumor electric field therapy system, comprising: at least one pair of the aforementioned electrode sheets; an electric field generator, the electric field generator being used to generate an alternating power supply and transmit the alternating power supply to each of the electrode sheets through the alternating power supply line; a control unit, the control unit being used to configure at least one of the switching state of the control switch and the switching state of the switching unit, so as to sample the temperature detection signals of one or more combinations of all temperature detection units based on the corresponding temperature sampling points, or to control at least one of the electrode units of the row group to be applied with the alternating electric signal based on the alternating power supply line.

[0050] To achieve the above-mentioned objectives, the fourth embodiment of the present application provides a tumor treatment device, including: the aforementioned tumor electric field treatment system.

[0051] To achieve the above-mentioned purpose, the fifth aspect of the present application provides an electrode sheet temperature detection method, which is applied to the aforementioned tumor electric field therapy system or the aforementioned tumor electric field therapy system. The method includes: controlling the switching unit so that the dual-purpose signal line corresponding to each row group in the corresponding electrode sheet is connected to the corresponding temperature sampling point in sequence; controlling the control switch corresponding to each column group so as to sample the temperature detection signal of the corresponding electrode unit based on the corresponding temperature sampling point.

[0052] To achieve the above-mentioned purpose, the sixth aspect of the present application provides an electrode sheet abnormality detection method, in which a preset threshold value and a preset temperature threshold value are preset in the adapter or electric field generator. The method includes: determining the temperature detection signal of each electrode unit in each of the electrode sheets by executing the aforementioned electrode sheet temperature detection method; and judging whether the electrode sheet has an abnormality based on the temperature detection signal.

[0053] Furthermore, judging whether the electrode sheet is abnormal according to the temperature detection signal includes: if it is determined according to the temperature detection signal that any electrode unit in the corresponding electrode sheet is abnormal or faulty, judging that the electrode sheet is unqualified.

[0054] Furthermore, determining whether the electrode sheet is abnormal is based on the temperature detection signal, including: when it is determined based on the temperature detection signal that there are abnormal or faulty electrode units in the corresponding electrode sheet, determining the number of abnormal or faulty electrode units; when the number of abnormal or faulty electrode units reaches a preset threshold, determining that the electrode sheet needs to be replaced.

[0055] Furthermore, judging whether the electrode sheet is abnormal based on the temperature detection signal includes: comparing the temperature of each electrode unit in the corresponding electrode sheet with a preset temperature threshold based on the temperature detection signal; and judging whether the temperature of the electrode sheet is abnormal based on the comparison result.

[0056] Furthermore, judging whether the temperature of the electrode sheet is abnormal based on the comparison result includes: determining that the temperature of the electrode sheet is abnormal when the temperature of any electrode unit in the corresponding electrode sheet exceeds a preset temperature threshold.

[0057] To achieve the above-mentioned purpose, the seventh embodiment of the present application provides a control method for a tumor electric field therapy system, wherein a preset temperature threshold, a preset quantity threshold, a first preset temperature and a second preset temperature are preset in the adapter or electric field generator, and the method includes: determining the temperature detection signal of each electrode unit in each electrode sheet by executing the aforementioned electrode sheet temperature detection method; and controlling the intensity of the alternating electric signal applied to the electrode unit according to the temperature detection signal.

[0058] Furthermore, the intensity of the alternating electric signal applied to the electrode unit is controlled according to the temperature detection signal, including: comparing the temperature of each electrode unit in the electrode sheet with a preset temperature threshold according to the temperature detection signal; and controlling the intensity of the alternating electric signal according to the comparison result.

[0059] Furthermore, the intensity of the alternating electric signal is controlled according to the comparison result, including: when the temperature of at least one electrode unit exceeds a preset temperature threshold, stopping applying the alternating electric signal to the electrode unit of the electrode sheet.

[0060] Furthermore, stopping applying the alternating electric signal to the electrode units of the electrode sheet includes: stopping applying the alternating electric signal to all electrode units of the electrode sheet; or stopping applying the alternating electric signal to all electrode units in the row group of the electrode units in the electrode sheet that exceed a preset temperature threshold.

[0061] Furthermore, the intensity of the alternating electric signal is controlled according to the comparison result, including: determining the number of over-temperature row groups when the temperature at at least one electrode unit exceeds a preset temperature threshold; stopping applying the alternating electric signal to all electrode units of the electrode sheet when the number of over-temperature row groups exceeds a preset number threshold; or stopping applying the alternating electric signal to all electrode units in the row group where the electrode unit exceeding the preset temperature threshold is located in the electrode sheet when the number of over-temperature row groups does not exceed the preset number threshold.

[0062] Furthermore, when the application of the alternating electric signal to all electrode units in the row group where the electrode unit exceeding the preset temperature threshold is located in the electrode sheet is stopped, the method further includes: continuing to apply the alternating electric signal to the electrode units in other row groups in the electrode sheet.

[0063] Furthermore, the intensity of the alternating electric signal applied to the electrode units in other row groups in the electrode sheet is adjustable.

[0064] Furthermore, the intensity of the alternating electric signal applied to the electrode units of each row group in the other row groups is adjustable.

[0065] Furthermore, the intensity of the alternating electric signal is controlled according to the comparison result, including: when the temperature at all electrode units in the electrode sheet does not exceed the preset temperature threshold, and when the temperature at all electrode units in the electrode sheet does not exceed the first preset temperature, increasing the intensity of the alternating electric signal applied to the electrode units of the electrode sheet, wherein the first preset temperature is lower than the preset temperature threshold.

[0066] Furthermore, when the temperatures at all electrode units in the electrode sheet do not exceed the preset temperature threshold, the method also includes: when the temperature at at least one electrode unit in the electrode sheet exceeds the first preset temperature and is less than the preset temperature threshold, the alternating electric signal strength currently applied to the electrode unit of the electrode sheet is maintained unchanged.

[0067] Furthermore, when the temperatures at all electrode units in the electrode sheet do not exceed the preset temperature threshold, the method also includes: when the temperature at at least one electrode unit in the electrode sheet exceeds a second preset temperature and is less than the preset temperature threshold, reducing the intensity of the alternating electric signal applied to the electrode unit of the electrode sheet, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0068] Furthermore, when the number of the over-temperature row groups does not exceed the preset number threshold, the method also includes: when the temperature at each electrode unit in the non-over-temperature row group does not exceed the first preset temperature, increasing the intensity of the alternating electric signal applied to the electrode unit of the non-over-temperature row group, wherein the first preset temperature is less than the preset temperature threshold.

[0069] Furthermore, when the number of the over-temperature row groups does not exceed the preset number threshold, the method also includes: when the temperature of at least one electrode unit in the non-over-temperature row group exceeds the first preset temperature and is less than the preset temperature threshold, the alternating electric signal strength currently applied to the electrode unit of the non-over-temperature row group is maintained unchanged.

[0070] Furthermore, when the number of the over-temperature row groups does not exceed the preset number threshold, the method also includes: when the temperature of at least one electrode unit in the non-over-temperature row group exceeds a second preset temperature and is less than a preset temperature threshold, reducing the intensity of the alternating electric signal applied to the electrode unit of the non-over-temperature row group, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0071] Furthermore, the electric field strengths corresponding to the row groups whose alternating electric signal strengths are increased have the same increase amplitude.

[0072] Furthermore, the increasing extents of the electric field intensities corresponding to the row groups whose alternating electric signal intensities are increased are different from each other.

[0073] Furthermore, maintaining the strength of the alternating electric signal currently applied to the electrode unit unchanged includes: maintaining the strength of the alternating electric signal currently applied to the first target row group unchanged, wherein the first target row group is a row group where the temperature at the electrode unit exceeds a first preset temperature and is less than a preset temperature threshold.

[0074] Furthermore, reducing the intensity of the alternating electric signal applied to the electrode unit includes: reducing the intensity of the alternating electric signal applied to the electrode unit of the second target row group, wherein the second target row group is a row group where the temperature at the electrode unit exceeds the second preset temperature and is less than the preset temperature threshold.

[0075] To achieve the above-mentioned purpose, the eighth embodiment of the present application provides an electrode sheet type identification method, which includes: determining the temperature detection signal of each electrode unit in each electrode sheet by executing the aforementioned electrode sheet temperature detection method; and identifying the type of the electrode sheet based on the temperature detection signal.

[0076] To achieve the above-mentioned purpose, the ninth embodiment of the present application provides a computer-readable storage medium on which a computer program is stored. When the computer program is executed by a processor, it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0077] To achieve the above-mentioned purpose, the tenth embodiment of the present application provides an adapter for tumor electric field therapy, including a first memory and a first controller, wherein the first memory stores a computer program, and when the computer program is executed by the first controller, it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0078] To achieve the above-mentioned purpose, the eleventh embodiment of the present application provides an electric field generator for tumor electric field therapy, including a second memory and a second controller, wherein the second memory stores a computer program, and when the computer program is executed by the second controller, it implements the aforementioned electrode sheet temperature detection method; or the aforementioned electrode sheet abnormality detection method; or the aforementioned tumor electric field therapy system control method; or the aforementioned electrode sheet type identification method.

[0079] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0080] Figure 1 A schematic diagram of a tumor treating field system according to an embodiment of the present application;

[0081] Figure 2 for Figure 1 The schematic diagram of the structure of the electrode sheet of the tumor electric field treatment system shown;

[0082] Figure 3 for Figure 1 A schematic diagram of the circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system is shown;

[0083] Figure 4 for Figure 1 The schematic diagram of the structure of the electrode unit of the tumor electric field treatment system shown;

[0084] Figure 5 for Figure 1 A schematic diagram of the circuit connection between an electrode sheet, an adapter, and an electric field generator of the tumor electric field treating system is shown;

[0085] Figure 6 for Figure 1 A schematic block diagram of the internal structure of the adapter of the tumor electric field treatment system is shown;

[0086] Figure 7 for Figure 1 A schematic block diagram of the internal structure of an electric field generator of a tumor treating field system is shown;

[0087] Figure 8 This is a flow chart of a method for detecting electrode temperature according to an embodiment of the present application;

[0088] Figure 9 This is a flow chart of a method for detecting abnormality of an electrode sheet according to an embodiment of the present application;

[0089] Figure 10 1 is a flow chart of a control method of a tumor treating field system according to an embodiment of the present application;

[0090] Figure 11 This is a flow chart of a method for identifying electrode sheet types according to an embodiment of the present application;

[0091] Figure 12 This is a flow chart of a signal control method for tumor electric field therapy according to an embodiment of the present application;

[0092] Figure 13 This is a flow chart of a method for detecting electrode temperature according to another embodiment of the present application;

[0093] Figure 14 This is a flow chart of a method for applying an alternating electric signal for tumor electric field therapy according to another embodiment of the present application;

[0094] Figure 15 Schematic diagram of a flow chart of a method for applying an alternating electric signal based on a temperature detection signal according to an embodiment of the present application;

[0095] Figure 16 This is a flow chart of a method for applying an alternating electric signal based on a temperature detection signal according to another embodiment of the present application;

[0096] Figure 17 A schematic diagram of a tumor treating field system according to another embodiment of the present application;

[0097] Figure 18 A schematic diagram of a tumor treating field system according to another embodiment of the present application;

[0098] Figure 19 for Figure 18 A schematic diagram of the circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system is shown;

[0099] Figure 20 A schematic diagram of a tumor treating field system according to another embodiment of the present application;

[0100] Figure 21 A schematic diagram of a tumor treating field system according to another embodiment of the present application;

[0101] Figure 22 A schematic diagram of the circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0102] Figure 23 A schematic diagram of the circuit connection between an electrode sheet and an adapter of a tumor electric field treating system according to another embodiment of the present application;

[0103] Figure 24 A schematic diagram of a tumor treating field system according to another embodiment of the present application;

[0104] Figure 25 for Figure 24 A schematic diagram of the circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system is shown;

[0105] Figure 26 A schematic diagram of the circuit connection between an electrode sheet and an adapter of a tumor electric field treating system according to another embodiment of the present application;

[0106] Figure 27 A schematic diagram of a tumor treating field system according to another embodiment of the present application;

[0107] Figure 28 A schematic diagram of the circuit connection between an electrode sheet, an adapter, and an electric field generator of a tumor electric field treating system according to another embodiment of the present application;

[0108] Figure 29 for Figure 27 The schematic diagram of the structure of the electrode unit of the tumor electric field treatment system shown;

[0109] Figure 30 for Figure 28 A schematic block diagram of the internal structure of the adapter of the tumor electric field treatment system is shown;

[0110] Figure 31 for Figure 28 A schematic block diagram of the internal structure of an electric field generator of a tumor treating field system is shown;

[0111] Figure 32 This is a flow chart of a control method of a tumor treating field system according to another embodiment of the present application;

[0112] Figure 33 FIG. 4 is a flow chart of a signal control method for tumor electric field therapy according to another embodiment of the present application.

[0113] Description of reference numerals:

[0114] Tumor treatment field treatment system 100, 100A to 100H, or 100', electrode sheet 13, 13A to 13H, or 13', first cable 15 or 15', adapter 20, 20A to 20B, 20E to 20H, or 20', second cable 25 or 25', electric field generator 30 or 30', substrate 31 or 31', electrode unit 33, 33A to 33H, or 33', temperature detection unit 35 or 35', ground terminal 35-1 or 35-1', signal terminal 35-2 or 35-2', temperature sensor 34 or 34', ground terminal 34-1 or 34-1', signal terminal 34-2 or 34-2', diode 36 or 36', anode 36-1 or 36-1', cathode 36-2 or 36- 2', a second power supply module 32 or 32', a second controller 37 or 37', a second communication unit 38 or 38', an AC signal generator 39 or 39', a power switch 40 or 40', a first controller 51 or 51', an ADC unit 52 or 52', a voltage divider resistor 53 or 53', a control switch 54, 54B, 54E to 54H or 54', a first control switch 54-1, 54-1B, 54-1E to 54-1H or 54-1', a second control switch 54-2, 54-2B, 54-2E to 54-2H or 54-2', a third control switch 54-3, 54-3B, 54-3E to 54-3H or 54-3', a fourth control switch 54-4, 54-4B, 54-4 E to 54-4H or 54-4', a fifth control switch 54-5, 54-5B, 54-5E to 54-5H or 54-5', a bidirectional switch 55, 55B, 55E to 55H or 55', a first bidirectional switch 55-1, 55-1B, 55-1E to 55-1H or 55-1', a second bidirectional switch 55-2, 55-2B, 55-2E to 55-2H or 55-2', a third bidirectional switch 55-3, 55-3B, 55-3E to 55-3H or 55-3', a fourth bidirectional switch 55-4, 55-4B, 55-4E to 55-4H or 55-4', a first communication unit 56 or 56', an alternating power line 57 or 57', a first power cord Source module 58 or 58', ground line 18, 18B, 18E to 18H or 18', first ground line 18-1, 18-1B, 18-1E to 18-1H or 18-1', second ground line 18-2, 18-2B, 18-2E to 18-2H or 18-2', third ground line 18-3, 18-3B, 18-3E to 18-3H or 18-3', fourth ground line 18-4, 18-4B, 18-4E to 18-4G or 18-4', fifth ground line 18-5, 18-5B or 18-5', dual-purpose signal line 19, 19B, 19E to 19H or 19', first dual-purpose signal line 19-1, 19-1B, 19-1E to 19-1H or 19-1',Second dual-purpose signal line 19-2, 19-2B, 19-2E to 19-2H or 19-2', third dual-purpose signal line 19-3, 19-3B, 19-3E to 19-3H or 19-3', fourth dual-purpose signal line 19-4, 19-4E to 19-4F or 19-4', first connector 60 or 60', first plug 61, first socket 62, second connector 70 or 70', second plug 71 or 71', second socket 72 or 72'. DETAILED DESCRIPTION

[0115] The following embodiments of the technical solution of the present application will be described in detail with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present application and are therefore only examples and are not intended to limit the scope of protection of the present application.

[0116] Example 1:

[0117] Figure 1 FIG. 1 is a schematic diagram of a tumor electric field treatment system 100 according to an embodiment of the present application. Figure 1 As shown, the tumor electric field treatment system 100 includes: at least one pair of electrode sheets 13, an adapter 20 connected to the at least one pair of electrode sheets 13, and an electric field generator 30 connected to the adapter 20. The at least one pair of electrode sheets 13 can be arranged in pairs on the patient's body surface, such as Figure 1 There are four electrode sheets 13 in the apparatus, and every two electrode sheets 13 are arranged as a pair on the patient's body surface. The electric field generator 30 is used to supply power to at least one pair of electrode sheets 13, so that an alternating electric field for treating tumors is generated between at least one pair of electrode sheets 13. The adapter 20 is electrically connected between at least one pair of electrode sheets 13 and the electric field generator 30, and is used to transmit the alternating electric signal generated by the electric field generator 30 to at least one pair of electrode sheets 13. In other words, the electric field generator 30 is capable of generating an alternating electric signal, and the alternating electric signal generated by the electric field generator 30 is transmitted to each electrode sheet 13 through the adapter 20, so that an alternating electric field for treating tumors is generated between the same pair of electrode sheets 13, so as to apply an alternating electric field to the tumor site of the patient for tumor treatment.

[0118] like Figure 1 As shown, in this embodiment, there are four electrode sheets 13, each of which includes a plurality of electrode units 33 of the same number. Each electrode unit 33 is electrically connected to the adapter 20, and the number of electrode units 33 on each electrode sheet 13 is 20. In other embodiments, the tumor electric field therapy system 100 may have more or fewer electrode sheets 13; in other embodiments, each pair of electrode sheets 13 may have the same number of electrode units 33, while different pairs of electrode sheets 13 may have different numbers of electrode units 33; in still other embodiments, the number of electrode units 33 on each electrode sheet 13 may be 9, 13, etc.

[0119] In this embodiment, if Figure 1 As shown, from the perspective of the spatial structure of the electrode sheet 13, the connection line between the two electrode units 33 can be called a connecting strip (unnumbered), and the distance between the electrode units 33 can be adjusted by the connecting strip (unnumbered). If an electrode unit 33 is connected to another electrode unit 33 only by a connecting strip (unnumbered), then the electrode unit 33 is an electrode unit 33 at a free end, for example Figure 1 Each electrode sheet 13 shown has nine electrode units 33 at free ends. The space surrounding the electrode units 33 at the free ends is open space, meaning the electrode units 33 at the free ends have a certain degree of freedom and can move freely within the open space. For example, the connecting band (not numbered) can be stretched or bent to a certain extent, allowing the electrode units 33 to move in various directions. The reason some electrode units 33 are arranged at free ends in this embodiment is that after the electrode sheet is applied to the human body, the electric fields of the electrode units 33 are inconsistent due to skin wrinkles and corresponding impedance changes, resulting in inconsistent temperatures among the electrode units 33. Furthermore, the electrode units 33 located at the periphery of the electrode sheet 13 heat up faster. Therefore, if some electrode units 33 in the electrode sheet 13 are at free ends, the electrode units 33 at the free ends can be adjusted to increase the heat dissipation space of the peripheral electrode units 33, thereby accelerating heat dissipation. Furthermore, the application position of the electrode units 33 at the free ends on the human body can be adjusted, allowing the electrode units 33 at the free ends to be flexibly applied to the human body according to actual needs. Specifically, the electrode sheet 13 in this embodiment has a total of 20 electrode units 33 arranged in an array of four rows and six columns. The first and fourth rows each have four electrode units 33, and the second and third rows each have six electrode units 33. The four electrode units 33 in each of the first and fourth rows are located in each of the second to fifth columns, respectively, and the six electrode units 33 in each of the second and third rows are located in each of the first to sixth columns, respectively. The electrode sheet 13 is provided with a number of connecting strips (unnumbered) connecting two adjacent electrode units 33, and a bridging portion (unnumbered) connected to the first cable 15. The bridging portion (unnumbered) connects the adjacent two electrode units 33 located in the third row and the third column and the third row and the fourth column. The 20 electrode units 33 can be divided into a left part including the three columns on the left and a right part including the three columns on the right. The left part and the right part are connected only by the bridging portion (unnumbered), that is, along the row upward, there is no connecting strip (unnumbered) between the electrode unit 33 located in the third column and the adjacent electrode unit 33 located in the fourth column, but an open space is formed; and along the column upward, only the adjacent two electrode units 33 in the third and fifth columns are connected by the connecting strip (unnumbered), and the adjacent two electrode units 33 in each of the other four columns are not provided with a connecting strip.

[0120] Figure 3 for Figure 1 The circuit connection diagram of the electrode sheet 13 and the adapter 20 of the tumor electric field treatment system 100 is shown. Figure 4 Schematic diagram of the structure of the electrode unit 33 is shown. It is worth noting that: Figure 3 The arrangement of the electrode units 33 is shown to more clearly illustrate the electrical connection between an electrode sheet 13 and the adapter 20. Figure 3 The arrangement of the electrode units 33 shown does not represent the arrangement of the electrode units 33 in a spatial structure. Figure 3 It is shown that one end of the bidirectional switching switch 55 provided in the adapter 20 is turned on and the other end is turned off to obtain the temperature detection signal of the temperature detection unit 35 of the electrode unit 33 in the corresponding electrode sheet 13. In another example, when an alternating electric signal needs to be applied to the electrode unit 33 in the corresponding electrode sheet 13, one end of the bidirectional switching switch 55 is controlled to be turned off and the other end is turned on. That is, each bidirectional switching switch 55 has an alternating electric signal transmission point for transmitting the alternating electric signal (i.e., the two ends of the bidirectional switching switch 55) and a temperature sampling point for collecting the temperature detection signal (i.e., the one end of the bidirectional switching switch 55). Combined Figure 1 、 Figure 3 as well as Figure 4 The electrode sheet 13 includes: a substrate 31, a plurality of electrode units 33 electrically connected to the substrate 31 at intervals, a plurality of temperature detection units 35, and a first cable 15 electrically connected to the substrate 31. The substrate 31 can be a flexible circuit board. The substrate 31 is embedded with a plurality of conductive traces, and the plurality of conductive traces include a plurality of grounding wires 18 and a plurality of dual-purpose signal wires 19. The first cable 15 has a multi-core conductor (not shown), each of which is electrically connected to the multi-core grounding wire 18 and the multi-channel dual-purpose signal wire 19 of the substrate 31 in a one-to-one correspondence. In this embodiment, the total number of grounding wires 18 and dual-purpose signal wires 19 embedded in the substrate 31 does not exceed 9, and thus the number of conductors of the first cable 15 does not exceed 9.

[0121] The multiple electrode units 33 are arranged into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13 is provided with 20 electrode units 33. The 20 electrode units 33 are arranged in the order of 1 to 20 for circuit connection, and are divided into four row groups and five column groups. That is, the 20 electrode units 33 are arranged in four rows and five columns for circuit connection. Each electrode unit 33 is provided with a corresponding temperature detection unit 35. Each temperature detection unit 35 has a signal terminal 35-2 and a ground terminal 35-1. The electrode units 33 and the temperature detection units 35 are both soldered to the substrate 31. The electrode units 33 are short-circuited with the signal terminal 35-2 of the corresponding temperature detection unit 35. Because the multiple temperature detection units 35 are provided in a one-to-one correspondence with the multiple electrode units 33, the multiple temperature detection units 35 are also arranged in four rows and five columns for circuit connection. It should be noted that the arrangement here is to more clearly show the electrical connection between the electrode sheet 13 and the adapter 20, and does not represent the arrangement of the electrode unit 33 in the spatial structure. The spatial structure may be as follows: Figure 2 The illustrated structure, which is generally an array, can also be other structures, such as a petal-shaped or scattered pattern, and can be regular or irregular. The electrode units 33 are configured to apply alternating electrical signals to the patient's tumor site. The temperature detection unit 35 is configured to detect the temperature of the patient's body surface to which the electrode sheet 13 is applied, i.e., the temperature at the corresponding electrode unit 33, and output the temperature detection signal to the adapter 20. In this embodiment, the multiplexed signal lines 19 of the substrate 31 are provided in a one-to-one correspondence with the multiple row groups of electrode units 33, and are configured to transmit the alternating electrical signal generated by the electric field generator 30 to each electrode unit 33 in the corresponding row group. That is, the electrode units 33 in the same row group are short-circuited by the same dual-purpose signal line 19 of the substrate 31, while the electrode units 33 in different row groups are connected in parallel by different dual-purpose signal lines 19 of the substrate 31. The dual-purpose signal lines 19 of the substrate 31 are electrically connected to the first cable 15, and then electrically connected to the electric field generator 30 via the adapter 20. Furthermore, the dual-purpose signal line 19 of the substrate 31 receives the alternating electric signal generated by the electric field generator 30 through the first cable 15 and the adapter 20 .

[0122] Multiple grounding lines 18 are provided in a one-to-one correspondence with the multiple column groups of electrode units 33. The multiple grounding lines 18 are used to sequentially short-circuit each temperature detection unit 35 in each column group to ground. Specifically, the ground terminals 35-1 of the multiple temperature detection units 35 in the same column group are all short-circuited via the same grounding line 18 on the substrate 31. The ground terminals 35-1 of the temperature detection units 35 in different column groups are connected in parallel via different grounding lines 18 on the substrate 31. During the temperature detection period, only one of the multiple grounding lines 18 is conductive at any given time; the remaining grounding lines are disconnected. Each temperature detection unit 35 has a signal terminal 35-2 and a ground terminal 35-1 at its two ends. Multiple temperature sensing units 35 in the same row group are connected in series. The signal terminal 35-2 of a temperature sensing unit 35 at the end of each row group is connected to the DC power supply VCC via a series-connected bidirectional switch and a voltage divider resistor. The ground terminals 35-1 of the corresponding temperature sensing units 35 in each column group are connected together, then connected to the control switch 54 via a corresponding ground line in the multiple ground lines 18, and then to the ground pin GND. The tumor electric field therapy system 100 configures the switching timing of the bidirectional switch 55 and the control switch 54 so that the temperature sensing signals detected by one or more corresponding combinations of all temperature sensing units 35 in the electrode sheet 13 are sampled separately.

[0123] like Figure 3 As shown, all the temperature detection units 35 located in the same row group are connected in series to form a line (such as one of the dual-purpose signal lines 19-1, 19-2, 19-3, and 19-4) connected to the DC power supply VCC, and the ground terminals 35-1 of all the temperature detection units 35 located in the same row group are connected to the ground pin GND by five ground lines (such as the ground lines 18-1, 18-2, 18-3, 18-4, and 18-5). The ground terminals 35-1 of all the temperature detection units 35 located in the same column group are connected to the same ground line (such as one of the ground lines 18-1, 18-2, 18-3, 18-4, and 18-5). A row of temperature detection units 35 arranged in series are each connected in series to a bidirectional switch (e.g., bidirectional switch 55-1, 55-2, 55-3, or 55-4) and a voltage divider resistor (e.g., voltage divider resistor R1, R2, R3, or R4) at the DC power supply VCC terminal. The voltage divider resistor (e.g., voltage divider resistor R1, R2, R3, or R4) is closer to the DC power supply VCC terminal than the bidirectional switch 55 (e.g., bidirectional switch 55-1, 55-2, 55-3, or 55-4). Each ground line 18 is respectively connected in series to a control switch 54 (e.g., control switch 54-1, 54-2, 54-3, 54-4, or 54-5).

[0124] In this embodiment, each electrode unit 33 is equipped with a temperature detection unit 35 for temperature detection. The aforementioned circuit design reduces the number of conductors in the first cable 15, preventing cable thickness increases and stiffness that would otherwise increase cable fixation difficulty. Furthermore, the increased number of conductors in the first cable 15 prevents the adhesion between the electrode sheet 13 and the patient's body surface corresponding to the tumor site. The base plate 31 includes nine grounding wires 18 and two dual-purpose signal wires 19. Specifically, in this embodiment, the base plate 31 includes five grounding wires 18 and four dual-purpose signal wires 19. The number of grounding wires 18 is related to the number N of electrode unit columns, which is greater than or equal to the number of electrode unit columns. N is a positive integer. The number of dual-purpose signal wires 19 is related to the number M of electrode unit rows, which is greater than or equal to the number of electrode unit rows. M is a positive integer. The number of circuits L embedded in the base plate 31 of the electrode sheet 13 is equal to the sum of the number of grounding wires 18 and the number of dual-purpose signal wires 19. In this embodiment, the number of ground lines 18 is equal to the number N of column groups of electrode units 33 ; and the number M of row groups of electrode units 33 is equal to the number of dual-purpose signal lines 19 .

[0125] The plurality of electrode units 33 are arranged on the substrate 31 in a two-dimensional array. Figure 2 As shown, the electrode sheet 13 in this embodiment includes 20 electrode units 33, which are arranged in an array of four rows and six columns. The first and fourth rows each contain four electrode units 33, and the second and third rows each contain six electrode units 33. The four electrode units 33 in each of the first and fourth rows are located in each of the second to fifth columns, respectively. The six electrode units 33 in each of the second and third rows are located in each of the first to sixth columns, respectively. The five electrode units 33 located in the second and third columns of the first row and the first, second, and third columns of the second row are divided into Region 1. The five electrode units 33 located in the fourth and fifth columns of the first row and the fourth, fifth, and sixth columns of the second row are divided into Region 2. The five electrode units 33 located in the first, second, and third columns of the third row and the second and third columns of the fourth row are divided into Region 3. The five electrode units 33 located in the fourth, fifth, and sixth columns of the third row and the fourth and fifth columns of the fourth row are divided into Region 4. Each region (1-4) corresponds to a row group. In other embodiments, the 20 electrode units 33 may be arranged in other ways, and the 20 electrode units 33 may be divided into regions in other ways. Of course, in other embodiments, the electrode sheet 13 may also have other numbers of electrode units 33. In short, the implementation of the present application is not limited by the number and arrangement of the electrode units 33 of the electrode sheet 13.

[0126] Each electrode unit 33 can apply an alternating electric signal, and the electrode sheets 13 configured in pairs are used to apply an alternating electric field to the patient's tumor site. Optionally, the electrode unit 33 is a dielectric element, such as a ceramic sheet, or a polymer dielectric layer composed of a polymer material. Each temperature detection unit 35 is set corresponding to an electrode unit 33 to detect the temperature at the corresponding electrode unit 33. Each temperature detection unit 35 can be set at any position of the corresponding electrode unit 33, such as Figure 3 and Figure 4 As shown, in this embodiment, each electrode unit 33 is provided with a through-hole 331 suitable for mounting a temperature detection unit 35. For example, a through-hole 331 is provided through the middle of each electrode unit 33, and a corresponding temperature detection unit 35 is accommodated in the through-hole 331 of each electrode unit 33. Each temperature detection unit 35 has a ground terminal 35-1 and a signal terminal 35-2. Each temperature detection unit 35 includes a temperature sensor 34. The tumor electric field treatment system 100 also includes a plurality of diodes 36. The temperature sensor 34 has a signal terminal 34-2 and a ground terminal 34-1. The diodes 36 have an anode 36-1 and a cathode 36-2. The anode 36-1 of each diode 36 is connected to the ground terminal 35-1 of the corresponding temperature detection unit 35. The cathodes 36-2 of the diodes 36 corresponding to each column group are connected together and then connected to the ground pin GND via the corresponding control switch 54. Specifically, the anode 36-1 of the diode 36 is connected to the ground terminal 34-1 of the temperature sensor 34, and the cathode 36-2 of the diode 36 is connected to the ground pin GND via a corresponding control switch 54. The ground terminal 34-1 of the temperature sensor 34 serves as the ground terminal 35-1 of the temperature detection unit 35, and the signal terminal 34-2 of the temperature sensor 34 serves as the signal terminal 35-2 of the temperature detection unit 35. The temperature sensor 34 can be a thermistor or other temperature sensor other than a thermistor. Each temperature sensor 34 corresponds to a diode 36, which is connected in series with the corresponding temperature sensor 34. The diode 36 can prevent reverse current flow, thereby preventing the detection signal from other electrode units 33 from affecting the temperature sensor 34.

[0127] like Figure 3As shown, the electrode sheet 13 of this embodiment includes five grounding wires 18. Each grounding wire 18 is used to ground the ground terminals 35-1 of the temperature detection units 35 in the same column group. The five grounding wires 18 of the electrode sheet 13 are a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, a fourth grounding wire 18-4, and a fifth grounding wire 18-5. Among the five column groups of the electrode sheet 13, the first column group includes electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16; the second column group includes electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17; the third column group includes electrode unit 33-3, electrode unit 33-8, electrode unit 33-13, and electrode unit 33-18; the fourth column group includes electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19; and the fifth column group includes electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20. Specifically, the first grounding line 18-1 is used to ground the electrode units 33-1, 33-6, 33-11, and 33-16 in the first column group; the second grounding line 18-2 is used to ground the electrode units 33-1 and 33-2, the electrode units 33-6 and 33-7, the electrode units 33-11 and 33-12, and the electrode units 33-16 and 33-17 in series; the third grounding line 18-3 is used to ground the electrode units 33-1 to 33-3, the electrode units 33-6 to 33-8, and the electrode units 33-11 to 33-17 in series. 33-13, the electrode units 33-16 to the electrode units 33-18 connected in series are grounded; the fourth grounding line 18-4 is used to ground the electrode units 33-1 to the electrode units 33-4, the electrode units 33-6 to the electrode units 33-9, the electrode units 33-11 to the electrode units 33-14, and the electrode units 33-16 to the electrode units 33-19 connected in series; the fifth grounding line 18-5 is used to ground the electrode units 33-1 to the electrode units 33-5, the electrode units 33-6 to the electrode units 33-10, the electrode units 33-11 to the electrode units 33-15, and the electrode units 33-16 to the electrode units 33-20 connected in series. It should be noted that these grounding wires 18 can be selectively closed or disconnected, which can be achieved by connecting each grounding wire 18 in series with a control switch 54, that is, the grounding terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33 in each column group are connected to the ground pin through a control switch 54, which will be described in detail below. Figure 4The aforementioned "grounding electrode units 33" refers to connecting the ground terminal 34-1 of the corresponding temperature sensor 34 in each column group to the anode 36-1 of the corresponding diode 36, and then connecting them together through the cathode 36-2 of the corresponding diode 36. In short, each ground line 18 short-circuits the ground terminals 35-1 of the temperature detection units 35 corresponding to all electrode units 33 in each column group through diodes 36 and then to ground.

[0128] like Figure 3As shown, the electrode sheet 13 of this embodiment also includes four dual-purpose signal lines 19. One end of each dual-purpose signal line 19 is connected to all electrode units 33 in a corresponding row group and all temperature detection units 35 connected in series, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting alternating electrical signals. Specifically, the four dual-purpose signal lines 19 of the electrode sheet 13 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. The five electrode units 33, electrode unit 33-1 to electrode unit 33-5, are connected in series to the first dual-purpose signal line 19-1, and the temperature detection units 35 corresponding to the five electrode units 33, electrode unit 33-1 to electrode unit 33-5, are connected in series to the first dual-purpose signal line 19-1; the five electrode units 33, electrode unit 33-6 to electrode unit 33-10, are connected in series to the second dual-purpose signal line 19-2, and the temperature detection units 35 corresponding to the five electrode units 33, electrode unit 33-6 to electrode unit 33-10, are connected in series to the second dual-purpose signal line 19-2; The five electrode units 33, electrode units 33-11 through 33-15, are connected in series to the third dual-purpose signal line 19-3, and the temperature detection units 35 corresponding to the five electrode units 33, electrode units 33-11 through 33-15, are connected in series to the third dual-purpose signal line 19-3. The five electrode units 33, electrode units 33-16 through 33-20, are connected in series to the fourth dual-purpose signal line 19-4, and the temperature detection units 35 corresponding to the five electrode units 33, electrode units 33-16 through 33-20, are connected in series to the third dual-purpose signal line 19-4. In short, each dual-purpose signal line 19 connects the electrode units 33 in the same row group in series, and connects the temperature detection units 35 corresponding to the electrode units 33 in the same row group in series, and then connects them to the adapter 20. It should be noted that these dual-purpose signal lines 19 can selectively transmit alternating electrical signals or receive temperature detection signals. This can be achieved by connecting each dual-purpose signal line 19 in series with a bidirectional switch 55 and coordinating the closing or opening of the ground line 18.That is, the temperature detection units 35 in each row group are connected in series and the signal ends 35-2 of the temperature detection units 35 in each row group are short-circuited with the corresponding electrode units 33 respectively, and then connected to a switching unit (unnumbered) through a dual-purpose signal line 19. The switching unit (unnumbered) includes a plurality of bidirectional switching switches 55, which are configured to switch the dual-purpose signal line 19 to connect to the temperature sampling point (unnumbered) or the alternating power line 57, so that when the dual-purpose signal line 19 is connected to the temperature sampling point (unnumbered), the switching state of the control switch 54 is configured to enable the temperature detection signal detected by the corresponding temperature detection unit 35 in each column group to be sampled based on the temperature sampling point (unnumbered), and when the dual-purpose signal line 19 is connected to the alternating power line 57, an alternating electrical signal is applied to the electrode units 33 of at least one row group based on the alternating power line 57. The details will be described in detail below.

[0129] The multiple ground lines 18 and the multiplexed signal lines 19 are conductive traces embedded in the substrate 31. The substrate 31 is electrically connected to the first cable 15. The multiple ground lines 18 and the multiplexed signal lines 19 embedded in the substrate 31 are electrically connected to corresponding wires (not shown) in the first cable 15.

[0130] The tumor electric field therapy system 100 of this embodiment includes at least one pair of the aforementioned electrode sheets 13, an adapter 20 electrically connected to the electrode sheets 13, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheets 13 and the electric field generator 30. The electric field generator 30 provides alternating electrical signals to the multiple electrode units 33 of the electrode sheet 13 via the adapter 20 and the dual-purpose signal line 19 of the electrode sheet 13, or is used to receive temperature detection signals output by the temperature detection units 35 corresponding to the multiple electrode units 33. The adapter 20 transmits the alternating electrical signals generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode sheet 13, and is also configured to receive the temperature detection signals output by the multiplexed dual-purpose signal line 19 of the electrode sheet 13.

[0131] refer to Figure 3As shown, the adapter 20 includes: a first controller 51, multiple sets of ADC units 52 connected to the first controller 51, multiple sets of voltage-dividing resistors 53 and multiple sets of control switches 54 corresponding to the multiple sets of ADC units 52, multiple sets of bidirectional switches 55 connected to the multiple sets of ADC units 52, a first communication unit 56, an alternating power line 57 connected to each set of bidirectional switches 55, and a first power module 58 connected to the first communication unit 56, the first controller 51, and the multiple sets of ADC units 52. The first power module 58 provides a DC power supply VCC to the various electronic components of the adapter 20. The adapter 20 also includes multiple circuit lines (unnumbered), which are electrically connected to the multiple ground lines 18 and the multiplexed signal lines 19 in the substrate 31 of the corresponding electrode sheet 13 through the first cables 15 of the corresponding electrode sheet 13. The multiple circuit lines (unnumbered) include multiple alternating power lines 57 that transmit alternating electrical signals to corresponding electrode sheets 13 and are electrically connected to the multiplexed signal lines 19 within the substrate 31 of the corresponding electrode sheet 13, multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiplexed signal lines 19 within the substrate 31 of the corresponding electrode sheet 13 and are used to supply power to each temperature detection unit 35 of the electrode sheet 13 or transmit the temperature detection signal of the electrode sheet 13, and multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground lines 18 within the substrate 31 of the corresponding electrode sheet 13. The number L of circuit lines electrically connected to one electrode sheet 13 by the adapter 20 is equal to the sum of the number of rows and columns of the electrode units 33 of the electrode sheet 13; the number H of circuit lines electrically connected to X electrode sheets 13 by the adapter 20 is equal to X times the number of circuit lines electrically connected to a single electrode sheet 13, that is, H = XL = X*(M+N). The number of control switch groups 54 and the number of bidirectional switch groups 55 are both related to the number of electrode sheets 13. The number of control switch groups 54 is the same as the number of bidirectional switch groups 55, and is not less than the number of electrode sheets 13. Optionally, the number of control switch groups 54 and the number of bidirectional switch groups 55 are both the same as the number of electrode sheets 13. The following is a detailed description of the electrical connection between an electrode sheet 13 having 20 electrode units 33 and the adapter 20 as an example.

[0132] Each group of control switches 54 is provided with a plurality of control switches 54, and the plurality of control switches 54 are respectively connected to the adapter 20 and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multi-way grounding lines 18 of the corresponding electrode sheet 13, and are configured to control the conduction or disconnection of the multi-way grounding lines 18. The circuit lines (not numbered) of the multi-way grounding lines 18 electrically connected to the electrode sheet 13 are grounded at one end close to the control switch 54. The number of control switches 54 in each group of control switches 54 is related to the number of grounding lines 18 of the substrate 31 of the corresponding electrode sheet 13, and the two are equal in this embodiment. Figure 3As shown, in this embodiment, the multiple control switches 54 in each group of control switches 54 are respectively a first control switch 54-1, a second control switch 54-2, a third control switch 54-3, a fourth control switch 54-4, and a fifth control switch 54-5. The multiple control switches 54 in the same group each control the closing or opening of the corresponding ground line 18 of the same electrode sheet 13. The first control switch 54-1 is used to control the closing or disconnection of the first grounding line 18-1 of the corresponding electrode sheet 13, and can cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature detection unit 35 corresponding to the four electrode units 33 in the first column group of the electrode sheet 13, namely, the electrode unit 33-1, the electrode unit 33-6, the electrode unit 33-11, and the electrode unit 33-16; the second control switch 54-2 is used to control the closing or disconnection of the second grounding line 18-2 of the electrode sheet 13, and can cooperate with the corresponding group of two-way switching switches 55 to control the multiple electrode units 33 in the first column group and the second column group of the electrode sheet 13 (the multiple electrode units can be: electrode unit 33-1 and electrode unit 33-2, electrode unit 33-6 and electrode unit 33 -7, electrode unit 33-11 and electrode unit 33-12, electrode unit 33-16 and electrode unit 33-17) corresponding to the temperature detection unit 35 is powered on and off; the third control switch 54-3 is used to control the closing or disconnection of the third ground line 18-3 of the electrode sheet 13, and can then cooperate with the corresponding group of two-way switching switches 55 to control the power on and off of each temperature detection unit 35 corresponding to the multiple electrode units 33 in the first column group, the second column group and the third column group of the electrode sheet 13 (the multiple electrode units can be: electrode units 33-1 to 33-3, electrode units 33-6 to 33-8, electrode units 33-11 to 33-13, electrode units 33-16 to 33-18); the same applies to the fourth control switch 54-4 and the fifth control switch 54-5. The above-mentioned control switch 54 can be a mechanical switch, such as a relay. The control switch 54 can also be an electronic switch, and each control switch 54 can be opened and closed by the first controller 51.

[0133] In this embodiment, the multiple groups of control switches 54 are all electronic switches. The first controller 51 is in communication with the multiple groups of control switches 54 and is used to sequentially and cyclically control the on / off states of the multiple control switches 54 in each group of control switches 54, thereby sequentially and individually connecting each of the multiple grounding wires 18 of the corresponding electrode sheet 13 and coordinating the switching of the corresponding bidirectional switch 55 to collect the patient's body surface temperature detected by all temperature detection units 35 on the electrode sheet 13. The number of control switches 54 in each group is no less than the number of grounding wires 18 on the substrate 31 of the corresponding electrode sheet 13. In this embodiment, the number of control switches 54 in each group is the same as the number of grounding wires 18 of the corresponding electrode sheet 13.

[0134] Each set of bidirectional switches 55 includes a plurality of bidirectional switches 55. The plurality of bidirectional switches 55 in each set are connected to the adapter 20 and are electrically connected to circuit lines (not numbered) corresponding one-to-one to the multiplexed signal lines 19 of a corresponding electrode sheet 13. The number of bidirectional switches 55 in each set of bidirectional switches 55 is related to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13, and is greater than or equal to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13. In this embodiment, the number of bidirectional switches 55 in each set of bidirectional switches 55 is equal to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13. Each bidirectional switch 55 has two ends marked 1 and 2. One end of the multiple bidirectional switches 55 in the same group is electrically connected one by one to the corresponding detection channels of the multiple detection channels of the corresponding group of ADC units 52 through the temperature sampling point (unnumbered). The two ends of each bidirectional switch 55 in the same group are electrically connected to the corresponding same alternating power line 57, and are configured to control the multi-channel dual-purpose signal line 19 to connect to the corresponding alternating power line 57 to transmit the alternating electrical signal or to connect to the corresponding detection channel of the corresponding group of ADC units 52 to receive the temperature detection signal output by the temperature detection unit 35.

[0135] like Figure 3As shown, taking the electrical connection between one electrode sheet 13 and the adapter 20 as an example, in this embodiment having 20 electrode units 33, the multiple bidirectional switches 55 in each group of bidirectional switches 55 are respectively a first bidirectional switch 55-1, a second bidirectional switch 55-2, a third bidirectional switch 55-3, and a fourth bidirectional switch 55-4. The multiple bidirectional switches 55 in the same group each control a corresponding one of the multiplexed signal lines 19 of the same electrode sheet 13 to switch between transmitting an alternating electrical signal and transmitting a temperature detection signal. Specifically, the first bidirectional switch 55-1 is used to control the switching between the transmission of the alternating electrical signal and the transmission of the temperature detection signal by the first dual-purpose signal line 19-1 of the corresponding electrode sheet 13, thereby controlling the switching between the conduction of each electrode unit 33 from the electrode unit 33-1 to the electrode unit 33-5 in the first row group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-1 to the electrode unit 33-5 in the first row group, and cooperates with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the first row of electrode units 33-1 to the electrode unit 33-5 to transmit the alternating electrical signal to the patient or enable the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to these electrode units 33 to be sampled and output to the corresponding ADC unit 52. The second bidirectional switch 55-2 is used to control the switching between the transmission of the alternating electrical signal and the transmission of the temperature detection signal by the second dual-purpose signal line 19-2 of the corresponding electrode sheet 13, thereby controlling the conduction of the electrode units 33 from the electrode unit 33-6 to the electrode unit 33-10 in the second row group of the electrode sheet 13 and the conduction of the signal terminals 35-2 of the temperature detection units 35 corresponding to the electrode units 33-6 to the electrode units 33-10 in the second row group, and cooperates with the corresponding control switches 54-1, 54-2, 54-3, 54-4, and 54-5 to enable the second row of electrode units 33-6 to the electrode unit 33-10 to transmit the alternating electrical signal to the patient or to enable the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to the electrode units 33 to be sampled and output to the corresponding ADC unit 52;The third bidirectional switch 55-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode sheet 13 between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33 from the electrode unit 33-11 to the electrode unit 33-15 in the third row group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit corresponding to the electrode unit 33-11 to the electrode unit 33-15 in the third row group, and cooperates with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the third row of electrode units 33-11 to the electrode unit 33-15 to transmit the alternating electric signal to the patient or enable the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to these electrode units 33 to be sampled and output to the corresponding ADC unit 52; The four bidirectional switching switches 55-4 are used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 13 between transmitting alternating electrical signals and transmitting temperature detection signals, thereby controlling the conduction of each electrode unit 33 from the electrode unit 33-16 to the electrode unit 33-20 in the fourth row group of the electrode sheet 13 and the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-16 to the electrode unit 33-20 in the fourth row group, and cooperating with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the fourth row electrode unit 33-16 to the electrode unit 33-20 to transmit alternating electrical signals to the patient or to enable the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to these electrode units 33 to be sampled and output to the corresponding ADC unit 52. When both ends of each set of bidirectional switches 55 are conductive and one end is disconnected, an alternating electrical signal can be transmitted to each electrode unit 33 of the corresponding electrode sheet 13. When each bidirectional switch 55 in each set of bidirectional switches 55 has one end conductive and two ends disconnected in sequence and in a time-sharing manner, and when all other bidirectional switches 55 have both ends conductive and one end disconnected, they can cooperate with each control switch 54 in the corresponding set of control switches 54 to transmit the temperature detection signal collected by the temperature detection unit 35 of each electrode unit 33 on the electrode sheet 13 in a time-sharing manner. The bidirectional switches 55 can be mechanical switches, such as relays. Alternatively, they can be electronic switches, and each bidirectional switch 55 can be switched by the first controller 51.

[0136] In this embodiment, the plurality of sets of bidirectional switches 55 are all electronic switches. The first controller 51 is in communication with the plurality of sets of bidirectional switches 55 and is configured to control the plurality of bidirectional switches 55 in each set of bidirectional switches 55 to switch between their respective terminals 1 and 2, and to coordinate the closing or opening of the corresponding control switch 54 to continuously monitor the patient's body surface temperature detected by all temperature detection units 35 on the electrode sheet 13 or to transmit an alternating electrical signal to the patient.

[0137] In this embodiment, each set of ADC units 52 is electrically connected to one end of each of the plurality of bidirectional switches 55 in the corresponding set of bidirectional switches 55 via a multi-channel circuit line (not numbered) within the adapter 20, and is configured to receive the temperature detection signal transmitted by the multiplexed signal line 19 of the corresponding electrode sheet 13, and convert the temperature detection signal from an analog signal to a digital temperature signal. Figure 3 As shown, each group of ADC units 52 includes a total of four detection channels A, B, C, and D, namely the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. Each detection channel A, B, C, and D is used to connect a corresponding dual-purpose signal line 19 in the multiple dual-purpose signal lines 19 and a corresponding temperature sampling point (unnumbered) through a corresponding bidirectional switch 55. Specifically, the first detection channel A is connected to the first dual-purpose signal line 19-1 through the first end of the first bidirectional switch 55-1, the second detection channel B is connected to the second dual-purpose signal line 19-2 through the first end of the second bidirectional switch 55-2, the third detection channel C is connected to the third dual-purpose signal line 19-3 through the first end of the third bidirectional switch 55-3, and the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 through the first end of the fourth bidirectional switch 55-4. Each detection channel A, B, C, and D is used to receive the temperature detection signal collected by the temperature detection unit 35 corresponding to the electrode unit 33 to which the corresponding dual-purpose signal line 19 is connected. In addition, each detection channel A, B, C, D is connected to a first power module 58 for providing detection voltage to the detection channel A, B, C, D via a corresponding voltage divider resistor 53 in the adapter 20. The first power module 58 provides DC power.

[0138] In this embodiment, the first communication unit 56 is configured to acquire digital temperature signals output by multiple sets of ADC units 52 and transmit the digital temperature signals to the electric field generator 30. The electric field generator 30 is further configured to control and adjust the voltage of the alternating electrical signal provided to the multiple electrode units 33 of the electrode sheet 13 based on the received digital temperature signals. For example, when any of the multiple digital temperature signals received exceeds a preset threshold, indicating that the temperature detected by the temperature detection unit 35 corresponding to at least one electrode unit 33 in the electrode sheet 13 exceeds a preset temperature threshold (e.g., 41°C, 42°C, etc.), the voltage of the alternating electrical signal output by the electric field generator 30 can be appropriately reduced to prevent the electrode units 33 of the electrode sheet 13 from overheating when the alternating electrical signal is applied, thereby preventing low-temperature burns on the patient's skin. The above-mentioned preset temperature threshold and the preset threshold can be determined based on human safety thresholds. The first communication unit 56 is controlled by the first controller 51 and serially transmits the digital temperature signals converted by the multiple sets of ADC units 52. In this embodiment, the preset temperature threshold can be a value within the range of 36°C-45°C.

[0139] refer to Figure 5 and Figure 6 In this embodiment, the first power module 58 is electrically connected to the second power module 32 of the electric field generator 30 and is configured to supply power to the first controller 51, the multiple ADC units 52, and the first communication unit 56 of the adapter 20. A first connector 60 is provided between each electrode sheet 13 and the adapter 20. The first connector 60 is suitable for connecting the corresponding electrode sheet 13 to the adapter 20. Figure 1 As shown, the first connector 60 includes a first plug 61 provided at the end of the first cable 15 away from the electrode sheet 13, and a first socket 62 provided on the adapter 20. The first plug 61 and the first socket 62 are press-type spring connectors, that is, the first connector 60 uses a connector to connect the adapter 20 to the electrode sheet 13. Each first cable 15 has four wires electrically connected to the two-way switches 55 in the corresponding group of two-way switches 55 and five wires electrically connected to the control switches 54 in the corresponding group of control switches 54. In other words, each first connector 60 is electrically connected to the corresponding group of two-way switches 55 and the corresponding group of control switches 54 of the adapter 20 through nine wires, and is connected to the electric field generator 30 through a corresponding alternating power line 57 of the adapter 20.

[0140] A second connector 70 is provided between the adapter 20 and the electric field generator 30. The second connector 70 is suitable for connecting the electric field generator 30 to the adapter 20. Figure 1As shown, the adapter 20 also includes a second cable 25 connected to a second connector 70. The second connector 70 includes a second plug 71 located at the end of the second cable 25 away from the first controller 51 and a second socket 72 located on the electric field generator 30. The second plug 71 and the second socket 72 are push-type spring connectors, that is, the second connector 70 uses a connector to connect the adapter 20 to the electric field generator 30. Each first connector 60, such as X1, Y1, X2, and Y2, is connected to the second connector 70 via a corresponding alternating power line 57. The first connectors 60, such as X1, Y1, X2, and Y2, are also connected to a corresponding set of control switches 54 and a corresponding set of ADC units 52. Each first connector 60 is connected to the second connector 70 and a corresponding set of ADC units 52 via a corresponding set of bidirectional switches 55. The second cable 25 has eight conductors, including four conductors 1 to 4 electrically connected to corresponding alternating power lines 57 for transmitting alternating electrical signals, a conductor 5 electrically connected to the data receiving line RX of the first communication unit 56, a conductor 6 electrically connected to the data transmitting line TX of the first communication unit 56, a conductor 7 electrically connected to the VCC power line of the first power module 58, and a conductor 8 electrically connected to the GND line of the first power module 58. A second connector 70 is connected to the first communication unit 56 via the data receiving line RX and the data transmitting line TX. The VCC pin of the second connector 70 is connected to the VVC power line of the first power module 58, and the GND pin of the second connector 70 is connected to the GND line of the first power module 58 and is grounded. The VCC pin of the second connector 70 is also connected to the corresponding set of voltage dividers 53 and the corresponding set of ADC units 52 via the VCC power line of the first power module 58.

[0141] refer to Figure 5 and Figure 7The electric field generator 30 includes a second power supply module 32, a second controller 37, an AC signal generator 39, a second communication unit 38, and a set of power switches 40. The VCC pin of the second connector 70 is also electrically connected to the VCC power line of the second power supply module 32, and the GND pin of the second connector 70 is grounded via the GND line of the second power supply module 32. The second power supply module 32 is also connected to the second controller 37 and the AC signal generator 39, respectively, and provides power to them. The second communication unit 38 is electrically connected to the wire 5 of the second connector 70 via its data receiving line RX and to the wire 6 of the second connector 70 via its data transmitting line TX, thereby enabling information exchange between the electric field generator 30 and the adapter 20. The second controller 37 is also electrically connected to the second communication unit 38, the AC signal generator 39, and a set of power switches 40. The second controller 37 is configured to control the opening and closing of each power switch 40 in the set of power switches 40 and adjust the relevant parameters of the alternating electrical signal applied by the AC signal generator 39 based on the relevant digital temperature signal received by the second communication unit 38 from the adapter 20. The AC signal generator 39 is electrically connected to the conductors 1 to 4 of the second connector 70 that transmit the alternating electrical signal through the set of power switches 40. The set of power switches 40 includes a plurality of power switches 40, and the plurality of power switches 40 are arranged in a one-to-one correspondence with the plurality of electrode sheets 13. Each power switch 40 is electrically connected to a corresponding conductor 1, 2, 3, 4 in the second connector 70 that transmits the alternating electrical signal through an AC power line 41-1, 41-2, 41-3, 41-4, and is electrically connected to the corresponding electrode sheet 13 through the corresponding conductor 1, 2, 3, 4 of the second connector 70, thereby transmitting the alternating electrical signal to each electrode sheet 13. The AC signal generator 39 is electrically connected to the set of power switches 40 via multiple AC power lines 41. Specifically, the number of power switches 40 in the electric field generator 30 is related to the number of electrode pads 13. In this embodiment, the number of power switches 40 is equal to the number of electrode pads 13, and both are four. The power switches 40 include a first power switch 40-1, a second power switch 40-2, a third power switch 40-3, and a fourth power switch 40-4, which are electrically connected to the wires 1 to 4 of the second connector 70 in a one-to-one correspondence.One end of the first power switch 40-1 is electrically connected to the AC signal generator 39 through the AC power line (unnumbered) of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 1 for transmitting the alternating electric signal in the second connector 70 through an AC power line 41-1, and is electrically connected to the alternating power line 57 at the port X1 of the adapter 20 through the conductor 1 of the second connector 70, the alternating power line 57 at the port X1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the alternating electric signal to the electrode sheet 13 electrically connected to the port X1 of the adapter 20 One end of the second power switch 40-2 is electrically connected to the AC signal generator 39 through the AC power line (unnumbered) of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 2 for transmitting alternating electric signals in the second connector 70 through an AC power line 41-2, and is electrically connected to the alternating power line 57 at the port Y1 of the adapter 20 through the conductor 2 of the second connector 70, the alternating power line 57 at the port Y1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the alternating electric signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20 One end of the third power switch 40-3 is electrically connected to the AC signal generator 39 through the AC power line (unnumbered) of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 3 for transmitting alternating electric signals in the second connector 70 through an AC power line 41-3 and electrically connected to the alternating power line 57 at the port X2 of the adapter 20 through the conductor 3 of the second connector 70, the alternating power line 57 at the port X2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the alternating electric signal to the electrode sheet 13 electrically connected to the port X2 of the adapter 20 One end of the fourth power supply switch 40-4 is electrically connected to the AC signal generator 39 through the AC power line (unnumbered) of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 4 for transmitting alternating electric signals in the second connector 70 through an AC power line 41-4 and electrically connected to the alternating power line 57 at the port Y2 of the adapter 20 through the conductor 4 of the second connector 70, the alternating power line 57 at the port Y2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20.

[0142] The following will refer to Figures 3 to 5The working principle of the tumor electric field treatment system 100 of this embodiment is described in detail.

[0143] Specifically, when it is necessary to detect the temperature of each electrode unit 33 of a certain electrode sheet 13, the second controller 37 of the electric field generator 30 controls the corresponding power switch 40 to disconnect the alternating electric signal applied to the electrode sheet 13; at the same time, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 configures the switching and switching timing of each control switch 54 and each bidirectional switch 55 in a group of control switches 54 electrically connected to the electrode sheet 13. At this time, the temperature detection signals of the temperature detection units 35 corresponding to one or more electrode units 33 in the corresponding row group can be collected respectively through the multiple detection channels A, B, C, and D of the group of ADC units 52 corresponding to the electrode sheet 13. The above temperature detection signals can be represented by resistance values. Only one of the five control switches 54 in the group of control switches 54 corresponding to the electrode sheet 13 can be turned on at the same time, and the other four can be turned off. In a group of bidirectional switches 55 corresponding to the electrode sheet 13, only one bidirectional switch 55 can have one end turned on and both ends turned off at any one time. The remaining bidirectional switches 55 can have both ends turned on and one end turned off. This allows the dual-purpose signal line 19 of the electrode sheet 13 to be electrically connected to and conductive to a corresponding detection channel A, B, C, or D of the corresponding ADC unit 52. With this arrangement, the ADC unit 52 can collect temperature detection signals from one or more combinations of temperature detection units 35 corresponding to the electrode units 33 in the row group corresponding to the turned-on bidirectional switch 55.

[0144] Specifically, the electric field generator 30 disconnects the alternating electric signal applied to the electrode sheet 13. The first bidirectional switch 55-1 is turned on at one end and turned off at two ends. The remaining bidirectional switches 55 (the second bidirectional switch 55-2, the third bidirectional switch 55-3, and the fourth bidirectional switch 55-4) are all turned on at two ends and turned off at one end. At the same time, the first control switch 54-1 is closed, the second control switch 54-2, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 are all turned off. The temperature detection unit 35 corresponding to the electrode unit 33-1 of the first row group is powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off. The ADC of this group is turned on at one end. The signal terminal 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A in the unit 52. Since only the ground terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is connected to the ground, and the ground terminals 35-1 of the remaining electrode units 33 are disconnected, only the temperature detection unit 35 corresponding to the electrode unit 33-1 on the first detection channel A of the group of ADC units 52 is effectively operating, and the temperature detection signal (resistance value) collected by the first detection channel A is the temperature detection signal (resistance value) of the temperature detection unit 35 corresponding to the electrode unit 33-1.

[0145] End 1 of the first bidirectional switch 55-1 is turned on and end 2 is turned off, and ends 2 of the remaining bidirectional switches 55 (second bidirectional switch 55-2, third bidirectional switch 55-3, and fourth bidirectional switch 55-4) are all turned on and ends 1 are all turned off. At the same time, the second control switch 54-2 is closed, and the first control switch 54-1, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 are all turned off. The temperature detection units 35 corresponding to the electrode units 33-1 to 33-2 of the first row group are powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off. The temperature detection units 35 corresponding to the short-circuited electrode unit 33-1 on the first detection channel A in the group of ADC units 52 are turned off. The signal terminal 35-2 and the ground terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-2 are connected to the ground, so the temperature detection units 35 corresponding to the electrode unit 33-1 to the electrode unit 33-2 on the first detection channel A of the group of ADC units 52 are effectively operating. The temperature detection signal (resistance) collected by the first detection channel A is the temperature detection signal (resistance) of the temperature detection units 35 corresponding to the electrode unit 33-1 to the electrode unit 33-2 after the merger. The temperature detection signal (resistance) of the temperature detection unit 35 corresponding to the electrode unit 33-1 is subtracted from the temperature detection signal (resistance) of the temperature detection unit 35 corresponding to the electrode unit 33-2.

[0146] End 1 of the first bidirectional switch 55-1 is turned on and end 2 is turned off, and ends 2 of the remaining bidirectional switches 55 (second bidirectional switch 55-2, third bidirectional switch 55-3, and fourth bidirectional switch 55-4) are all turned on and ends 1 are all turned off. At the same time, the third control switch 54-3 is closed, and the first control switch 54-1, the second control switch 54-2, the fourth control switch 54-4, and the fifth control switch 54-5 are all turned off. The temperature detection units 35 corresponding to the electrode units 33-1 to 33-3 of the first row group are energized, and the temperature detection units 35 corresponding to the remaining electrode units 33 are de-energized. The signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A of the ADC unit 52 of this group. , the ground terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-3 is connected to the ground, so the temperature detection units 35 corresponding to the electrode unit 33-1 to the electrode unit 33-3 on the first detection channel A of the group of ADC units 52 are effectively operating, and the temperature detection signal (resistance) collected by the first detection channel A is the temperature detection signal (resistance) after the merger of the temperature detection units 35 corresponding to the electrode unit 33-1 to the electrode unit 33-3. The temperature detection signal (resistance) of the temperature detection unit 35 corresponding to the electrode unit 33-3 is obtained by subtracting the temperature detection signal (resistance) after the merger of the temperature detection units 35 corresponding to the electrode unit 33-1 to the electrode unit 33-2.

[0147] End 1 of the first bidirectional switch 55-1 is turned on and end 2 is turned off, and ends 2 of the remaining bidirectional switches 55 (second bidirectional switch 55-2, third bidirectional switch 55-3, and fourth bidirectional switch 55-4) are all turned on and ends 1 are all turned off. At the same time, the fourth control switch 54-4 is closed, and the first control switch 54-1, the second control switch 54-2, the third control switch 54-3, and the fifth control switch 54-5 are all turned off. The temperature detection units 35 corresponding to the electrode units 33-1 to 33-4 of the first row group are energized, and the temperature detection units 35 corresponding to the remaining electrode units 33 are de-energized. The signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A of the ADC unit 52 of this group. , the ground terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-4 is connected to the ground, so the temperature detection units 35 corresponding to the electrode units 33-1 to the electrode units 33-4 on the first detection channel A of the group of ADC units 52 are effectively operating, and the temperature detection signal (resistance) collected by the first detection channel A is the temperature detection signal (resistance) after the merger of the temperature detection units 35 corresponding to the electrode units 33-1 to the electrode units 33-4. The temperature detection signal (resistance) of the temperature detection unit 35 corresponding to the electrode units 33-1 to the electrode units 33-3 is subtracted from the merged temperature detection signal (resistance) to obtain the temperature detection signal (resistance) of the temperature detection unit 35 corresponding to the electrode unit 33-4.

[0148] End 1 of the first bidirectional switch 55-1 is turned on and end 2 is turned off, and ends 2 of the remaining bidirectional switches 55 (second bidirectional switch 55-2, third bidirectional switch 55-3, and fourth bidirectional switch 55-4) are all turned on and end 1 is turned off. At the same time, the fifth control switch 54-5 is closed, and the first control switch 54-1, the second control switch 54-2, the third control switch 54-3, and the fourth control switch 54-4 are all turned off. The temperature detection units 35 corresponding to the electrode units 33-1 to 33-5 of the first row group are energized, and the temperature detection units 35 corresponding to the remaining electrode units 33 are de-energized. The signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A of the ADC unit 52 of this group. , the ground terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-5 is connected to the ground, so the temperature detection units 35 corresponding to the electrode unit 33-1 to the electrode unit 33-5 on the first detection channel A of the group of ADC units 52 are effectively operating, and the temperature detection signal (resistance) collected by the first detection channel A is the temperature detection signal (resistance) after the merger of the temperature detection units 35 corresponding to the electrode unit 33-1 to the electrode unit 33-5. The temperature detection signal (resistance) of the temperature detection unit 35 corresponding to the electrode unit 33-1 to the electrode unit 33-4 is subtracted from the merged temperature detection signal (resistance) to obtain the temperature detection signal (resistance) of the temperature detection unit 35 corresponding to the electrode unit 33-5.

[0149] Thus, the temperature detection signals (resistance values) of the temperature detection units 35 corresponding to all the electrode units 33 in the first row group of the electrode sheet 13 are obtained. Similarly, the temperature detection signals (resistance values) of the temperature detection units 35 corresponding to the electrode units 33 in the remaining rows can be obtained.

[0150] Thus, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can collect the temperature detection signals of the temperature detection units 35 corresponding to all electrode units 33 of a particular electrode sheet 13 by controlling a set of bidirectional switches 55 and a set of control switches 54 that are electrically connected to the electrode sheet 13. That is, the switching unit (unnumbered) is configured to switch the dual-purpose signal lines 19 of the corresponding row group to the corresponding temperature sampling points (unnumbered), and by configuring the switching states of the control switches 54 of the corresponding column group, the temperature detection signal of a single temperature detection unit 35 or the combined temperature detection signal of multiple temperature detection units 35 can be obtained. Similarly, the temperature detection signals of the temperature detection units 35 of each electrode unit 33 of other electrode sheets 13 can be obtained.

[0151] The first controller 51 or the second controller 37, the plurality of ADC units 52 and the plurality of bidirectional switches 55 can automatically perform operations according to pre-programmed program codes. For example, the first controller 51 or the second controller 37 first controls all the bidirectional switches 55 in the corresponding group of bidirectional switches 55 to switch to end 1 so that all ends 1 of the bidirectional switches 55 are turned on and all ends 2 are turned off so that the dual-purpose signal lines 19 of the corresponding electrode sheet 13 are electrically connected to the corresponding group of ADC units 52. Then, the control switch 54-1 in the corresponding group of control switches 54 is closed and the remaining control switches 54-2 to 54-5 in the group of control switches 54 are turned off. During this period, the detection signals of the ADC units 52 in the group are detected by the first controller 51 or the second controller 37. Channels A, B, C, and D acquire the temperature detection signals of each temperature detection unit 35 corresponding to each electrode unit 33 in the first column group of the corresponding electrode sheet 13, convert them into digital temperature signals, and store them in a separately provided memory. Then, after a preset time interval, the first controller 51 or the second controller 37 closes the control switch 54-2 in the group of control switches 54 and opens the control switches 54-1, 54-3, 54-4, and 54-5 in the group of control switches 54. During this period, the detection channels A, B, C, and D of the ADC unit 52 acquire the temperature detection signals of a single temperature detection unit 35 or the combined temperature detection signals of multiple temperature detection units 35. By sequentially opening each control switch 54 in the group of control switches 54, the temperature detection signals of all temperature detection units 35 on the electrode sheet 13 can be obtained. Similarly, through this operation, the temperature detection signals of all temperature detection units 35 on at least one pair of electrode sheets 13 can be obtained.

[0152] The first controller 51 serially transmits the digital temperature signal obtained by the ADC unit 52 from the temperature detection signals of each temperature detection unit 35 through the first communication unit 56 , for example, to the electric field generator 30 .

[0153] It should be noted that in other embodiments, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control a set of bidirectional switches 55 and a set of control switches 54 electrically connected to a particular electrode sheet 13 to collect temperature detection signals from the temperature detection units 35 corresponding to some of the electrode units 33 of the electrode sheet 13 during the same temperature collection time period. For example, within the same collection time period, only the temperature detection signal from the temperature detection unit 35 corresponding to a single electrode unit 33 in a row group can be sampled. Similarly, within other collection time periods, the temperature detection signals from one or more temperature detection units 35 corresponding to the electrode units 33 of other row groups can be sampled. That is, the switching unit (unnumbered) is configured to switch the dual-purpose signal line 19 corresponding to each row group to the corresponding temperature sampling point (unnumbered), and by configuring the switching state of the control switch 54, the temperature detection signals detected by the single or multiple temperature detection units 35 in each row group are sampled separately. It should be noted that in other embodiments, the temperature detection signals of the temperature detection units 35 corresponding to single or multiple electrode units 33 in each of the two-row group or three-row group can also be sampled within the same acquisition time period. The details will not be elaborated here.

[0154] Specifically, when an alternating electric signal needs to be applied to each electrode unit 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each of the plurality of bidirectional switches 55 in a group of bidirectional switches 55 electrically connected to the electrode sheet 13 to have two ends connected and one end disconnected, and controls a power switch 40 electrically connected to the electrode sheet 13 to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply an alternating electric signal to each electrode unit 33 of the electrode sheet 13 via the alternating power line 57, and the voltage or current of the applied alternating electric signal is adjustable. That is, the switching unit (unnumbered) is configured to switch the dual-purpose signal lines 19 corresponding to at least two row groups to be connected to the alternating power line 57 at the same time, so that the electrode units 33 of at least two row groups are simultaneously applied with alternating electric signals based on the alternating power line 57.

[0155] It should be noted that in other embodiments, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control a group of bidirectional switches 55 electrically connected to a certain electrode sheet 13 to apply an alternating electric signal to some of the electrode units 33 of the electrode sheet 13 in the same time period. For example, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the first bidirectional switch 55-1 among the multiple bidirectional switches 55 in the group of bidirectional switches 55 electrically connected to the electrode sheet 13 to have both ends turned on and one end turned off, and the remaining bidirectional switches 55 to have one end turned on and both ends turned off, and simultaneously controls all control switches 54 to be turned off, and controls a power switch 40 electrically connected to the electrode sheet 13 to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply an alternating electric signal to the first row group of electrode units 33-1 to 33-5 located in the electrode sheet 13 through the alternating power line 57, and the voltage or current of the applied alternating electric signal is adjustable. That is, the switching unit (not numbered) is configured to switch the dual-purpose signal lines 19 corresponding to each row group to be connected to the alternating power line 57, so that the electrode units 33 of each row group are simultaneously applied with an alternating electrical signal based on the alternating power line 57. It should be noted that in other embodiments, the alternating electrical signal can also be applied to the electrode units 33 of two or three row groups simultaneously within the same time period, which will not be further described in detail here.

[0156] It should be noted that in the embodiment of the present application, the control switch 54 electrically connected to each of the multiple grounding lines 18 of the electrode sheet 13 and the bidirectional switch 55 electrically connected to each of the multiple dual-purpose signal lines 19 of the electrode sheet 13 are both provided in the adapter 20. However, in other embodiments, the control switch 54 electrically connected to the grounding line 18 and the bidirectional switch 55 electrically connected to the dual-purpose signal line 19 may also be provided on the electrode sheet 13 or provided in the electric field generator 30, which will not be described in detail here. In addition, the ADC unit 52 provided in the adapter 20 may also be provided in the electric field generator 30 and directly controlled by the second controller 37.

[0157] The tumor electric field therapy system 100 of the present application can realize real-time and comprehensive monitoring of the temperature of all electrode units 33 on the electrode sheet 13 without increasing the weight of the electrode sheet 13 or increasing the core of the first cable 15 electrically connected to the electrode sheet 13, and then determine whether the electrode sheet 13 is qualified based on the obtained temperature detection signal; or determine whether the temperature detection unit 35 of the electrode sheet 13 is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 13 needs to be replaced based on the number of faulty or abnormal temperature detection units 35 obtained; or if the electrode sheet is qualified, identify the type of the electrode sheet based on the obtained temperature detection signal; or if the electrode sheet is qualified, determine whether the electrode unit 33 of the electrode sheet 13 is overheated based on the obtained temperature detection signal, and then control the alternating electric signal applied to the electrode sheet 13 or the electrode unit 33 of the corresponding row of the electrode sheet 13, so as to avoid low-temperature burns on the patient's body surface when tumor treatment is performed through the electrode sheet 13. In addition, the substrate 31 of the electrode sheet 13 of the present application is electrically connected to the same electrode unit 33 and the signal end 35-2 of the corresponding temperature detection unit 35 through the same dual-purpose signal line 19. While it can transmit both alternating electrical signals and direct current signals for temperature signal acquisition and the collected temperature detection signals through the dual-purpose signal line 19, it also greatly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) laid thereon, reducing the wiring difficulty of the substrate 31, simplifying the manufacturing process, reducing the weight of the substrate 31, and reducing manufacturing costs. The electrode sheet 13 of the present application can also switch between applying alternating electrical signals for tumor treatment and transmitting direct current signals for temperature acquisition and transmitting the collected temperature detection signals through the combined control of a control switch 54 electrically connected to the grounding line 18 laid thereon and a bidirectional switching switch 55 electrically connected to the dual-purpose signal line 19.

[0158] Specifically, when it is necessary to apply an alternating electric signal to the patient through the electrode units 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls all the control switches 54 in a group of control switches 54 corresponding to the electrode sheet 13 to be disconnected, and at the same time controls all the bidirectional switching switches 55 in a group of bidirectional switching switches 55 corresponding to the electrode sheet 13 to be switched to their respective two ends, so that one end of these bidirectional switching switches 55 are all disconnected and the two ends are all turned on to realize that all the dual-purpose signal lines 19 of the electrode sheet 13 are electrically connected to the adapter 20 and an alternating power line 57 corresponding to the electrode sheet 13, thereby transmitting the alternating electric signal to the electrode units 33 of the electrode sheet 13.When the temperature detection signals of the temperature detection units 35 corresponding to all the electrode units 33 of the detected electrode sheet 13 are much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue to generate an alternating electric signal with an increased voltage or current amplitude, or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 13 through a corresponding alternating power line 57 of the adapter 20, so that the pair of electrode sheets 13 continue to apply the alternating electric signal; when the temperature detection signals of the temperature detection units 35 corresponding to all the electrode units 33 of the detected electrode sheet 13 are lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue to generate an alternating electric signal with an increased voltage or current amplitude, or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 13 through a corresponding alternating power line 57 of the adapter 20, so that the pair of electrode sheets 13 continue to apply the alternating electric signal; The generator 30 can reduce the voltage or current of the alternating electric signal generated by the AC signal generator 39 through the second controller 37, thereby reducing the voltage or current of the alternating electric signal applied to the pair of electrode sheets 13; when it is detected that a temperature detection signal converted from the temperature detection unit 35 corresponding to an electrode unit 33 of a certain electrode sheet 13 is greater than a preset temperature threshold, the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode sheet 13 to be disconnected through the second controller 37 to stop applying the alternating electric signal to the electrode sheet 13; or the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 controls all the bidirectional switching switches 55 in a group of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to be automatically disconnected. Its 2 ends are switched to 1 end, that is, all 1 ends of the two-way switching switches 55 of a group of two-way switching switches 55 electrically connected to the electrode sheet 13 are controlled to be turned on and all 2 ends are turned off, thereby stopping the application of the alternating electric signal to the electrode sheet 13; or, when it is detected that a temperature detection signal converted from the temperature detection unit 35 corresponding to an electrode unit 33 of a certain electrode sheet 13 is greater than a preset temperature threshold, the second controller 37 of the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode sheet 13 to continue to be turned on, and the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 controls a two-way switching switch 55 electrically connected to the electrode unit 33 of the electrode sheet 13 to switch from its 2 ends to its 1 end. end, and the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 simultaneously controls the remaining bidirectional switching switches 55 electrically connected to the electrode units 33 in different rows whose temperatures obtained by converting the temperature detection signal of the electrode sheet 13 do not exceed the preset temperature threshold and whose temperature detection signals exceed the converted temperature preset temperature threshold, to continue to maintain electrical connection with their respective two ends, so as to stop applying the alternating electric signal to all the electrode units 33 in the row where the electrode unit 33 whose temperature obtained by converting the temperature detection signal of the electrode sheet 13 exceeds the preset temperature threshold and to continue applying the alternating electric signal to the electrode units 33 in the remaining rows whose temperatures obtained by converting the temperature detection signal of the electrode sheet 13 do not exceed the preset temperature threshold.Thus, the method for controlling the application of the alternating electric signal based on the temperature detection signal of the tumor electric field therapy system 100 is realized.

[0159] The present application embodiment provides an electrode sheet temperature detection method, which is applied to the above-mentioned electrode sheet 13 or tumor electric field treatment system 100, referring to Figure 8 As shown, it includes the following steps:

[0160] Step 210: Control the switching unit so that the dual-purpose signal lines 19 corresponding to each row group in the corresponding electrode sheet 13 are connected to the corresponding temperature sampling points in sequence.

[0161] Specifically, the power supply switch 40 of the electric field generator 30 is controlled to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, and at the same time, each of the two-way switching switches 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to turn on one end and disconnect the other two ends in turn, and one end of the remaining two-way switching switches 55 are turned on and both ends are disconnected to connect the DC signal applied to the signal end 35-2 of the temperature detection unit 35 corresponding to each electrode unit 33 in a row group of the electrode sheet 13.

[0162] Further, each bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to switch in turn from its end electrically connected to the alternating electric signal to its end electrically connected to the direct electric signal, and the remaining bidirectional switching switches 55 are switched from its end electrically connected to the direct electric signal to its end electrically connected to the alternating electric signal, that is, each bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch in turn from its 2 ends to its 1 end, and the remaining bidirectional switching switches 55 are switched from its 1 end to its 2 ends; or, each bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to switch in turn the electrode unit 33 of each electrode unit 33 in a row group corresponding to the bidirectional switching switch 55 in the electrode sheet 13 from the on state to the off state, and at the same time, the signal end 35-2 of the temperature detection unit 35 corresponding to each electrode unit 33 in a row group corresponding to the bidirectional switching switch 55 in the electrode sheet 13 is switched from the off state to the on state.

[0163] Step 220 : Control the control switch 54 corresponding to each column group to sample the temperature detection signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0164] Specifically, the control switch 54 electrically connected to the ground terminal 35-1 of the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode sheet 13 is turned on in a time-sequential manner, and cooperates with the bidirectional switching switch 55 to obtain the temperature detection signal of the temperature detection unit 35 corresponding to each electrode unit 33 of the electrode sheet 13.

[0165] In some embodiments, when the dual-purpose signal lines 19 corresponding to each row group are connected to the corresponding temperature sampling points in sequence, the control switches 54 corresponding to each column group are controlled, including: controlling the control switches 54 corresponding to each column group to be closed in sequence to respectively sample the temperature detection signals of each electrode unit 33 in each row group.

[0166] The electrode sheet temperature detection method of the present application can quickly and accurately obtain the temperature of all electrode units of the electrode sheet; and based on the obtained temperature detection signals of all temperature detection units of the electrode sheet, it can be judged whether the temperature detection units of the electrode sheet are faulty, whether there is an abnormality, whether the electrode sheet is qualified, or whether it needs to be replaced; it can also be judged whether each electrode unit of the electrode sheet is overheated based on the obtained temperature detection signals of all temperature detection units of the electrode sheet when each temperature detection unit of the electrode sheet is normal, and then the alternating electric signal applied to the electrode sheet or applied to each electrode unit of the electrode sheet can be controlled; it can also be used to identify the type of electrode sheet when there is no abnormality in the temperature detection signals of each temperature detection unit of the electrode sheet.

[0167] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the embodiment of the present application is provided with a preset threshold, a first preset temperature, a second preset temperature and a preset temperature threshold, wherein the first preset temperature is lower than the second preset temperature, and the second preset temperature is lower than the preset temperature threshold.

[0168] Reference Figure 9 As shown, the present application also provides a method for detecting abnormal temperature of an electrode sheet, which includes the following steps:

[0169] Step 210: Control the switching unit so that the dual-purpose signal lines 19 corresponding to each row group in the corresponding electrode sheet 13 are connected to the corresponding temperature sampling points in sequence.

[0170] Step 220 : Control the control switch 54 corresponding to each column group to sample the temperature detection signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0171] Step 230: Determine whether the electrode sheet 13 is abnormal based on the temperature detection signal.

[0172] In some embodiments, determining whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0173] Step 231: Compare the temperature of each electrode unit 33 in the corresponding electrode sheet 13 with a preset temperature threshold based on the temperature detection signal. Specifically, the temperature obtained by converting the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 can be compared with the preset temperature threshold.

[0174] Step 232: Determine whether the temperature of the electrode sheet 13 is abnormal based on the comparison result. Specifically, determine whether the temperature of each electrode unit 33 in the electrode sheet 13 is abnormal based on the comparison result.

[0175] The comparison results in step 232 include not exceeding the preset temperature threshold and exceeding the preset temperature threshold. Not exceeding the preset temperature threshold includes being far below the preset temperature threshold and being close to the preset temperature threshold. The preset temperature threshold is 40°C-42°C. Optionally, the preset temperature threshold is 40.5°C-41.5°C. Optionally, the preset temperature threshold is 41°C-41.5°C. Optionally, the preset temperature threshold is 41°C.

[0176] The process of determining whether the temperature of the electrode sheet 13 is abnormal based on the comparison result in step 232 is as follows: if the temperature of any electrode unit 33 in the corresponding electrode sheet 13 exceeds a preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is abnormal. If the temperature of all electrode units 33 in the corresponding electrode sheet 13 does not exceed the preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is not abnormal.

[0177] In other embodiments, determining whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0178] Step 233: When it is determined according to the temperature detection signal that any one of the electrode units 33 in the corresponding electrode sheet 13 is abnormal or faulty, the electrode sheet 13 is determined to be unqualified.

[0179] Specifically, based on the temperature detection signals detected by the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13, it is determined whether the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 have any abnormality or have failed. Then, based on whether the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 have any abnormality or have failed, it is determined whether the electrode sheet 13 is qualified. When the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 have any abnormality or have failed, the electrode sheet 13 is determined to be unqualified. When the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13 do not have any abnormality or have not failed, the electrode sheet 13 is determined to be qualified.

[0180] In some other embodiments, determining whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0181] Step 234 : When it is determined based on the temperature detection signal that an abnormal or faulty electrode unit 33 exists in the corresponding electrode sheet 13 , the number of the abnormal or faulty electrode units 33 is determined.

[0182] Step 235: When the number of abnormal or faulty electrode units 33 reaches a preset threshold, it is determined that the electrode sheet 13 needs to be replaced.

[0183] Specifically, based on the temperature detection signals obtained from the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13, it is determined whether there is an abnormality or a fault in the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13; and then, based on whether there is an abnormality or a fault in the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13, it is determined whether the electrode sheet 13 needs to be replaced.

[0184] For example, when the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or faulty, and the number of abnormal or faulty temperature detection units 35 exceeds a preset threshold, the electrode sheet 13 is determined to need to be replaced. When the number of abnormal or faulty temperature detection units 35 in the electrode sheet 13 does not exceed the preset threshold, the electrode sheet 13 is determined not to need to be replaced. The preset threshold is 20% of the total number of all temperature detection units 35 in the electrode sheet 13.

[0185] Reference Figure 10 As shown, the present application also provides a control method for a tumor electric field treatment system, which includes the following steps:

[0186] Step 210: Control the switching unit so that the dual-purpose signal lines 19 corresponding to each row group in the corresponding electrode sheet 13 are connected to the corresponding temperature sampling points in sequence.

[0187] Step 220 : Control the control switch 54 corresponding to each column group to sample the temperature detection signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0188] Step 240: Control the intensity of the alternating electric signal applied to the electrode unit 33 according to the temperature detection signal.

[0189] Specifically, when it is determined that the electrode sheet 13 does not need to be replaced, the alternating electrical signal applied to each electrode unit 33 in the electrode sheet 13 is controlled or adjusted based on the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13. In other words, steps 234-235 can be added between steps 240 and 220.

[0190] In some embodiments, controlling the intensity of the alternating electrical signal applied to the electrode unit 33 according to the temperature detection signal in step 240 specifically includes the following steps:

[0191] Step 241 : Compare the temperature of each electrode unit 33 in the electrode sheet 13 with a preset temperature threshold according to the temperature detection signal.

[0192] Step 242: Control the intensity of the alternating electric signal according to the comparison result.

[0193] In some embodiments, controlling the strength of the alternating electrical signal according to the comparison result in step 242 specifically includes:

[0194] Step 2421: If the temperature at at least one electrode unit 33 exceeds a preset temperature threshold, stop applying the alternating electrical signal to the electrode units 33 of the electrode sheet 13. Specifically, when the temperature detected by the temperature detection signals of all electrode units 33 of the electrode sheet 13 exceeds the preset temperature threshold, stop applying the alternating electrical signal to the electrode units 33 of the electrode sheet 13. If the temperature detected by the temperature detection signals of all electrode units 33 of the electrode sheet 13 does not exceed the preset temperature threshold, continue applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13.

[0195] In some embodiments, stopping applying the alternating electric signal to the electrode unit 33 of the electrode sheet 13 in step 2421 specifically includes: stopping applying the alternating electric signal to all electrode units 33 of the electrode sheet 13; or stopping applying the alternating electric signal to all electrode units 33 in the row group of the electrode unit 33 in the electrode sheet 13 that exceeds a preset temperature threshold.

[0196] Furthermore, while the application of the alternating electrical signal to all electrode cells 33 in the row group of the electrode cell 33 in the electrode sheet 13 that exceeds the preset temperature threshold is stopped, the alternating electrical signal continues to be applied to the electrode cells 33 in other rows of the electrode sheet 13. The intensity of the alternating electrical signal applied to the electrode cells 33 in other rows of the electrode sheet 13 is adjustable. For example, the alternating electrical signal continues to be applied to all electrode cells 33 in the electrode sheet 13 that have a temperature that does not exceed the preset temperature threshold and are in a different row from the electrode cell 33 whose temperature exceeds the preset temperature threshold, as converted from the temperature detection signal. This signal is adjustable.

[0197] In other embodiments, controlling the strength of the alternating electrical signal according to the comparison result in step 242 specifically includes:

[0198] Step 2422: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode units 33 of the electrode sheet 13, wherein the first preset temperature is less than the preset temperature threshold.

[0199] In step 2422, the electric field strengths corresponding to the row groups whose alternating electric signal strengths are increased have the same increase amplitude.

[0200] Step 2423: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperature at at least one electrode unit 33 in the electrode sheet 13 exceeds the first preset temperature and is less than the preset temperature threshold, the alternating electric signal strength currently applied to the electrode unit 33 of the electrode sheet 13 is maintained unchanged.

[0201] Step 2424: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperature at at least one electrode unit 33 in the electrode sheet 13 exceeds the second preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit 33 of the electrode sheet 13 is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0202] In step 2424, the electric field strength corresponding to the electrode units 33 of each row group whose alternating electric signal strength is reduced is reduced by the same magnitude.

[0203] Exemplarily, when the temperature obtained by converting the temperature detection signal is much lower than the preset temperature threshold, the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, or the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of maintaining the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged. When the temperature obtained by converting the temperature detection signal is close to the preset temperature threshold, the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of maintaining the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13.

[0204] In some other embodiments, controlling the intensity of the alternating electrical signal according to the comparison result in step 242 specifically includes:

[0205] Step 2425: When the temperature at at least one electrode unit 33 exceeds a preset temperature threshold, determine the number of over-temperature row groups.

[0206] Step 2426 : When the number of over-temperature row groups exceeds a preset number threshold, stop applying the alternating electrical signal to all electrode units 33 of the electrode sheet 13 .

[0207] Step 2427: When the number of over-temperature row groups does not exceed the preset number threshold, stop applying the alternating electrical signal to all electrode units 33 in the row group of the electrode unit 33 in the electrode sheet 13 where the electrode unit 33 exceeding the preset temperature threshold is located.

[0208] Furthermore, while stopping the application of the alternating electrical signal to all electrode cells 33 in the row group containing the electrode cell 33 that exceeds the preset temperature threshold in the electrode sheet 13, the alternating electrical signal continues to be applied to the electrode cells 33 in other row groups in the electrode sheet 13. The intensity of the alternating electrical signal applied to the electrode cells 33 in other row groups in the electrode sheet 13 is adjustable.

[0209] Step 2428: When the number of over-temperature row groups does not exceed the preset number threshold, if the temperature at each electrode unit 33 in the non-over-temperature row group does not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode unit 33 of the non-over-temperature row group, wherein the first preset temperature is less than the preset temperature threshold.

[0210] In step 2428, the electric field strengths corresponding to the row groups whose alternating electric signal strengths are increased have the same increase amplitude.

[0211] Step 2429: When the number of over-temperature row groups does not exceed the preset number threshold, if the temperature of at least one electrode unit 33 in the non-over-temperature row group exceeds the first preset temperature and is less than the preset temperature threshold, the alternating electric signal strength currently applied to the electrode unit 33 of the non-over-temperature row group is maintained unchanged.

[0212] Step 2430: When the number of over-temperature row groups does not exceed the preset number threshold, if the temperature of at least one electrode unit 33 in the non-over-temperature row group exceeds the second preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit 33 of the non-over-temperature row group is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0213] In step 2430, the electric field strength corresponding to each row group whose alternating electric signal strength is reduced has the same reduction amplitude.

[0214] Exemplarily, when the temperature detection signal is much lower than the preset temperature threshold, the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, or the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of maintaining the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged. When the temperature detection signal approaches the preset temperature threshold, the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of maintaining the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or the alternating electric signal is continued to be applied to each electrode unit 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13.

[0215] Reference Figure 11 As shown, the present application also provides a method for identifying the type of electrode sheet, which includes the following steps:

[0216] Step 210: Control the switching unit so that the dual-purpose signal lines 19 corresponding to each row group in the corresponding electrode sheet 13 are connected to the corresponding temperature sampling points in sequence.

[0217] Step 220 : Control the control switch 54 corresponding to each column group to sample the temperature detection signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point.

[0218] Step 250: Identify the type of the electrode sheet 13 according to the temperature detection signal.

[0219] Specifically, when the electrode sheet 13 is qualified or there is no abnormality or failure in each temperature detection unit 35 of the electrode sheet 13, the type of the electrode sheet 13 is identified based on the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13.

[0220] The present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned tumor electric field therapy system 100 or for the above-mentioned electrode sheet 13. The method includes: combining and controlling the control switch 54 and the bidirectional switching switch 55 electrically connected to the electrode sheet 13 so that each electrode unit 33 of the electrode sheet 13 switches between applying an alternating electric signal and collecting a temperature detection signal.

[0221] Reference Figure 12 As shown, the present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned electrode sheet 13, and the method includes:

[0222] Step 310: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and executing step 320;

[0223] Step 320 : Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to collect temperature detection signals of the electrode units 33 of the electrode sheet 13 in rows and executing step 330 ;

[0224] Step 330: Determine the combined control mode of the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 according to the collected temperature detection signal and execute step 340;

[0225] Step 340 : Control the working state of each electrode unit 33 of the electrode sheet 13 according to the determined combined control mode of the control switch 54 and the bidirectional switch 55 .

[0226] The operating state of each electrode unit 33 of the electrode sheet 13 in step 340 includes at least one of: stopping applying the alternating electrical signal and continuing to collect the temperature detection signal; and stopping collecting the temperature detection signal and continuing to apply the alternating electrical signal. Continuing to apply the alternating electrical signal includes continuing to apply the alternating electrical signal by increasing the voltage or current amplitude of the currently applied alternating electrical signal, continuing to apply the alternating electrical signal by maintaining the voltage or current amplitude of the currently applied alternating electrical signal unchanged, or continuing to apply the alternating electrical signal by reducing the voltage or current amplitude of the currently applied alternating electrical signal.

[0227] The operating state of each electrode unit 33 of the electrode sheet 13 is determined by the temperature detection signal it collects. Each electrode unit 33 of the electrode sheet 13 is divided into different regions. Each electrode unit 33 in each region is controlled by a combination of a control switch 54 and a bidirectional switch 55 to cyclically switch between applying an alternating electrical signal and collecting a temperature detection signal.

[0228] This embodiment of the present application provides another electrode temperature detection method for the tumor electric field therapy system 100, please refer to Figure 13 As shown, the temperature detection method includes:

[0229] Step 510: disconnect the input of the alternating electrical signal of the electrode sheet 13, perform combination control on the multiple control switches 54 and the multiple bidirectional switches 55, and obtain the temperature detection signal of the temperature detection unit 35 of the electrode sheet 13 corresponding to each combination in all combinations;

[0230] Step 520: sampling and converting the temperature detection signal detected by each temperature detection unit 35 in the electrode sheet 13 to obtain a digital temperature signal;

[0231] Step 530: Transmit the digital temperature signal to the electric field generator 30 of the tumor electric field therapy system 100, so that the electric field generator 30 determines the temperature at the corresponding electrode unit 33 according to the digital temperature signal.

[0232] In step 510, the combined control of the plurality of control switches 54 and the plurality of bidirectional switches 55 specifically includes:

[0233] Step 511: Control the plurality of bidirectional switches 55 so that the dual-purpose signal lines 19 corresponding to each row group in the corresponding electrode sheet 13 are sequentially connected to the corresponding temperature sampling points; one bidirectional switch 55 is placed at end 1, and the remaining bidirectional switches 55 are placed at end 2, so as to electrically connect the signal terminals 35-2 of each temperature detection unit 35 corresponding to each electrode unit 33 in the row group corresponding to the bidirectional switch 55 placed at end 1 with the corresponding ADC unit 52;

[0234] Step 512: Sequentially and individually closing one of the plurality of control switches 54 in a time-sharing manner to collect the temperature detection signals detected by the temperature detection units 35 corresponding to the electrode units 33 in the corresponding row group one by one.

[0235] In step 512 , one of the plurality of control switches 54 is closed in sequence and in a time-sharing manner, so that the ADC unit 52 and each temperature detection unit 35 in the column group corresponding to the closed control switch 54 are grounded in sequence.

[0236] In this way, the temperature detection signals of the corresponding temperature detection units 35 in each row group can be obtained in turn, and then after processing by the adapter 20 or the electric field generator 30, the corresponding temperatures of all electrode units 33 on the electrode sheet 13 can be obtained, thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0237] For the tumor electric field therapy system 100 of the embodiment of the present application, the temperature of a single electrode unit 33 can be detected. For example, the temperature of a single electrode unit 33 located in the first column group can be detected. Taking electrode unit 33-1 as an example: disconnect the input of the alternating electric signal, set the bidirectional switch 55 corresponding to the row group where the electrode unit 33-1 that needs to be individually measured to end 1, and set the remaining bidirectional switches 55 to end 2; at the same time, turn on and ground the control switch 54 corresponding to the column group where the electrode unit 33-1 that needs to be individually measured to end, and turn off all the remaining control switches 54. In this way, the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-1 that needs to be individually measured can be sampled to obtain the temperature of the electrode unit 33-1. For example, bidirectional switch 55-1 corresponding to electrode unit 33-1 is set to terminal 1, and the remaining bidirectional switches (55-2 through 55-4) are all set to terminal 2. Simultaneously, control switch 54-1 corresponding to electrode unit 33-1 is closed and grounded, and the remaining control switches (54-2 through 54-5) are all opened. This allows the temperature of electrode unit 33-1 to be detected. Similarly, the temperatures of the other electrode units 33-6, 33-11, and 33-16 in the first column group can also be individually detected. In addition to temperature detection of a single electrode unit 33 located in the first column group, the temperature detection signals of other electrode units 33 are combined signals. For example, when the bidirectional switching switch 55-2 corresponding to the electrode unit 33-2 is placed at end 1, the remaining bidirectional switching switches (55-1, 55-3 to 55-4) are all placed at end 2; at the same time, the control switch 54-2 corresponding to the electrode unit 33-2 is closed and grounded, and the remaining control switches (54-1, 54-3 to 54-5) are all disconnected. At this time, the temperature detection signal obtained is the combined temperature detection signal of the electrode unit 33-1 and the electrode unit 33-2. The temperature detection signal of the electrode unit 33-2 can be obtained by subtracting the temperature detection signal of the electrode unit 33-1 from the combined temperature detection signal.

[0238] The present application also provides another method for applying an alternating electric signal for tumor electric field therapy, which is applied to the above-mentioned tumor electric field therapy system 100. Please refer to Figure 14 As shown, the alternating electric signal applying method includes:

[0239] Step 610: Determine the region (1-4) where the electrode unit 33 to which the alternating electrical signal is to be applied is located in the electrode sheet 13;

[0240] Step 611: Combining and controlling a plurality of control switches 54 and a plurality of bidirectional switches 55 electrically connected to the electrode sheet 13 to apply an alternating electrical signal.

[0241] In step 611, the combination of controlling the plurality of control switches 54 and the plurality of bidirectional switches 55 electrically connected to the electrode sheet 13 is specifically as follows:

[0242] Step 612: Disconnect all control switches 54 electrically connected to the electrode sheet 13;

[0243] Step 613: determining the row groups where the electrode units 33 in the areas where the alternating electric signals need to be applied are located according to the areas where the electrode units 33 in the areas where the alternating electric signals need to be applied are located;

[0244] Step 614: determining the bidirectional switches 55 electrically connected to the electrode units 33 in the row groups according to the row groups where the electrode units 33 to which the alternating electrical signals are applied are located;

[0245] Step 615: Control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be applied so that the electrode unit 33 to which the alternating electric signal needs to be applied is electrically connected to the alternating power line 57 to apply the alternating electric signal; at the same time, control the remaining bidirectional switching switches 55 so that the electrical connection between each electrode unit 33 in the area where the alternating electric signal does not need to be applied and the alternating power line 57 is disconnected to stop applying the alternating electric signal.

[0246] In step 615, "electrically connecting the electrode units to which alternating electric signals need to be applied to the alternating power line 57 to apply the alternating electric signals and disconnecting the electrical connection between the electrode units 33 in the area where the alternating electric signals do not need to be applied and the alternating power line 57 to stop applying the alternating electric signals" is achieved by placing the bidirectional switching switches 55 electrically connected to the electrode units 33 in the row groups corresponding to the areas (1-4) in the electrode sheet 13 to which the alternating electric signals are to be applied at their two ends, and placing all the bidirectional switching switches 55 electrically connected to the electrode units 33 in the remaining row groups at their one end.

[0247] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the embodiment of the present application is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2 and a preset temperature threshold t0, wherein the first preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0248] The present application also provides a method for applying an alternating electric signal based on a temperature detection signal, which is used in the above-mentioned tumor electric field treatment system 100. Figure 15 As shown, the application method includes:

[0249] Step 710: Start the tumor treating field system 100;

[0250] Step 711: Combining and controlling the control switch 54 (also called the grounding switch) electrically connected to the corresponding electrode sheet 13 and the bidirectional switch 55 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13;

[0251] Step 712: Combine and control the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0252] Step 713: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1. If there is no electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 714. If there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 715.

[0253] Step 714: Continue applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 712;

[0254] Step 715: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; if there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 716; if there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 717;

[0255] Step 716: Continue applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and return to step 712;

[0256] Step 717: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute step 718; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 719.

[0257] Step 718: Continue applying the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712;

[0258] Step 719: Determine the number of over-temperature regions and execute step 720, wherein the over-temperature region is a region containing electrode units whose temperature exceeds the preset temperature threshold t0, and the non-over-temperature region is a region in which the temperature of all electrode units does not exceed the preset temperature threshold t0;

[0259] Step 720: Determine whether the number of over-temperature areas exceeds a preset number threshold. If the number of over-temperature areas exceeds the preset number threshold, execute step 721. If the number of over-temperature areas does not exceed the preset number threshold, execute step 724.

[0260] Step 721: stop applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and execute step 722;

[0261] Step 722: Combine and control the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and execute step 723;

[0262] Step 723: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 711. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 722.

[0263] Step 724: Distinguish between an over-temperature area and a non-over-temperature area based on whether the area contains an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If the area is an over-temperature area, execute step 725; if the area is a non-over-temperature area, execute step 726.

[0264] Step 725: Stop applying the alternating electrical signal to each electrode unit 33 in the over-temperature area and execute step 731;

[0265] Step 726: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 727. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 728.

[0266] Step 727: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating electrical signal and execute step 731;

[0267] Step 728: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 729. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the second preset temperature t2, execute step 730.

[0268] Step 729: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and execute step 731;

[0269] Step 730: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 by reducing the voltage or current amplitude of the currently applied alternating electrical signal and execute step 731;

[0270] Step 731: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to re-acquire the temperature of each electrode unit 33 of the electrode sheet 13 and selecting to execute step 732 or step 734. The temperature of each electrode unit 33 of the electrode sheet 13 includes the temperature of each electrode unit 33 in the over-temperature area and the temperature of each electrode unit 33 in the non-over-temperature area.

[0271] Step 732: Determine whether the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1, execute step 733. If the temperature of each electrode unit 33 in the over-temperature area exceeds the first preset temperature t1, return to step 731.

[0272] Step 733: re-determine the area as a non-overtemperature area and execute step 734;

[0273] Step 734: Determine whether the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1. If the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1, execute step 735. If any of the temperatures of the electrode units 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 736.

[0274] Step 735: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 712;

[0275] Step 736: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2, execute step 737. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the second preset temperature t2, execute step 738.

[0276] Step 737: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and return to step 712;

[0277] Step 738: Determine whether the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the preset temperature threshold t0. If the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the preset temperature threshold t0, execute step 739. If any of the temperatures of the electrode units 33 in the non-overtemperature area exceeds the preset temperature threshold t0, return to step 719.

[0278] Step 739 : Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area in a manner of reducing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 712 .

[0279] The process of combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 711 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet is specifically as follows:

[0280] Disconnect all control switches 54 electrically connected to the corresponding electrode sheets 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 to the end that applies an alternating electrical signal to each electrode unit 33; or

[0281] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the alternating power line 57; or

[0282] All control switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective two ends.

[0283] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in steps 712, 722, and 731 is specifically as follows:

[0284] Controlling the power supply switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switches 55 electrically connected to the electrode sheet 13 to switch in time-sharing order from the end at which the alternating electric signal is applied to each electrode unit 33 to the end at which the temperature of each electrode unit 33 is collected, and controlling the remaining two-way switches 55 to switch in time-sharing order from the end at which the temperature of each electrode unit 33 is collected to the end at which the alternating electric signal is applied to each electrode unit 33, and closing the control switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in time-sharing order to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0285] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switches 55 electrically connected to the electrode sheet 13 to switch from both ends thereof, through which the alternating electric signal is applied to each electrode unit 33, to one end thereof in a time-sharing manner, and controlling the remaining two-way switches 55 to switch from one end thereof to both ends thereof, through which the alternating electric signal is applied to each electrode unit 33, and closing the control switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0286] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switches 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52, and controlling the remaining two-way switches 55 to switch the electrode sheet 13 from being electrically connected to the corresponding ADC unit 52 to being electrically connected to the alternating power line 57, and closing the control switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-divisional and sequential manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0287] The power supply switch 40 of the electric field generator 30 is controlled to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, and each of the two-way switching switches 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating electric signal to transmitting a direct current signal or a temperature detection signal in a time-sharing sequence. The remaining two-way switching switches 55 switch from transmitting a direct current signal or a temperature detection signal to transmitting an alternating electric signal, and close the control switches 54 electrically connected to each electrode unit 33 of the electrode sheet 13 in a time-sharing sequence to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0288] The first preset temperature in steps 713, 723, 726, 732, and 734 is 40°C to 40.3°C, preferably 40.2°C. The second preset temperature in steps 715, 728, and 736 is 40.4°C to 40.6°C, preferably 40.5°C. The preset temperature threshold in steps 717 and 738 is 41°C to 41.5°C, preferably 41°C. The preset quantity threshold in step 720 is preferably 2.

[0289] The process of continuing to apply the alternating electrical signal in steps 714, 716, 718, 727, 729, 730, 735, 737, and 739 is specifically as follows:

[0290] disconnecting the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time controlling the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied to connect the alternating electric signal transmission path electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to continue to be applied; or

[0291] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied to switch from its respective terminal 1 to its respective terminal 2 so as to continue to apply the alternating electrical signal to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied; or

[0292] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied, and at the same time control the two-way switch 55 electrically connected to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied, so that both ends of each of the two-way switch 55 are electrically connected to the alternating power line 57 so as to continue to apply the alternating electrical signal to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied; or

[0293] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied so that its two ends are closed and one end is disconnected, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to continue to be applied; or

[0294] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied so that the electrode unit 33 to which the alternating electric signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the alternating electric signal.

[0295] Increasing the voltage or current amplitude of the currently applied alternating electric signal in step 714, step 727, and step 735 specifically involves boosting the voltage of the currently applied alternating electric signal in a manner of a DC voltage amplitude increment of 0.03 V per second.

[0296] Continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal as described in steps 718, 730, and 739 specifically involves continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal by 5V and lasting for 3 minutes.

[0297] The process of stopping applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in step 721 is specifically as follows:

[0298] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the alternating power line 57; or

[0299] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from the end where the alternating electrical signal is applied to each electrode unit 33 to the end where the temperature of each electrode unit 33 is collected; or

[0300] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all two ends of the bidirectional switch 55, which apply alternating electrical signals to each electrode unit 33, to one end; or

[0301] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from electrically connecting each electrode unit 33 with the alternating power line 57 to electrically connecting each electrode unit 33 with the corresponding ADC unit 52; or

[0302] The bidirectional switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0303] The process of stopping applying the alternating electrical signal to each electrode unit 33 in the over-temperature area in step 725 is specifically as follows:

[0304] Control the bidirectional switch 55 electrically connected to the electrode units 33 in the over-temperature area to disconnect the electrical connection between the electrode units 33 in the over-temperature area and the alternating power line 57; or

[0305] Control the bidirectional switches 55 electrically connected to the electrode units 33 in the over-temperature zone to switch all ends thereof from the end where the electrode units 33 in the over-temperature zone are applied with alternating electrical signals to the end where the electrode units 33 in the over-temperature zone are subjected to temperature acquisition; or

[0306] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature zone to switch all two ends of the bidirectional switch 55, which applies an alternating electrical signal to each electrode unit 33 in the over-temperature zone, to one end; or

[0307] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area so that each electrode unit 33 in the over-temperature area switches from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52; or

[0308] The bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area is controlled to switch each electrode unit 33 in the over-temperature area from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0309] In the above control method, the tumor electric field therapy system 100 includes at least two pairs of electrodes 13 for alternately applying alternating electric fields with different directions. Each electrode 13 can alternately switch between applying alternating electric signals and transmitting temperature detection signals.

[0310] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the present embodiment is further provided with a third preset temperature t3, which is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. The present embodiment also provides an alternating electric signal control method based on a temperature detection signal for use in the above-mentioned tumor electric field therapy system, Figure 16 As shown, the alternating electric signal control method includes:

[0311] Step 810: Start the tumor treating field system 100;

[0312] Step 811: Combining and controlling the control switch 54 (also called the grounding switch) electrically connected to the corresponding electrode sheet 13 and the bidirectional switch 55 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13;

[0313] Step 812: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0314] Step 813: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1. If there is no electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 814. If there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, execute step 815.

[0315] Step 814: Continue applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 812;

[0316] Step 815: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; if there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 816; if there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 817;

[0317] Step 816: Continue applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and return to step 812;

[0318] Step 817: Determine whether there is an electrode unit 33 whose temperature exceeds the third preset temperature t3. If there is no electrode unit 33 whose temperature exceeds the third preset temperature t3, execute step 818; if there is an electrode unit whose temperature exceeds the third preset temperature t3, execute step 819.

[0319] Step 818: Continue applying the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0320] Step 819: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute step 820; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 821;

[0321] Step 820: Continue applying the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0322] Step 821: Determine the number of over-temperature regions and execute step 822, wherein the over-temperature region is a region containing electrode units whose temperatures exceed a preset temperature threshold t0, and the non-over-temperature region is a region in which the temperatures of all electrode units do not exceed the preset temperature threshold t0;

[0323] Step 822: Determine whether the number of over-temperature areas exceeds a preset number threshold. If the number of over-temperature areas exceeds the preset number threshold, execute step 823. If the number of over-temperature areas does not exceed the preset number threshold, execute step 826.

[0324] Step 823: Stop applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and execute step 824;

[0325] Step 824: Combine and control the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and execute step 825;

[0326] Step 825: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 811. If no electrode unit 33 with a temperature exceeding the first preset temperature t1 exists on the electrode sheet 13, the process returns to step 824.

[0327] Step 826: Distinguish between an over-temperature area and a non-over-temperature area based on whether the area contains an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If the area is an over-temperature area, execute step 827; if the area is a non-over-temperature area, execute step 828.

[0328] Step 827: Stop applying the alternating electrical signal to each electrode unit 33 in the over-temperature area and execute step 835;

[0329] Step 828: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 829. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 830.

[0330] Step 829: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 by increasing the voltage or current amplitude of the currently applied alternating electrical signal and execute step 835;

[0331] Step 830: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2. If the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 831. If the temperature of each electrode unit 33 in the non-overtemperature area exceeds the second preset temperature t2, execute step 832.

[0332] Step 831: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and execute step 835;

[0333] Step 832: Determine whether any of the electrode units 33 in the non-overtemperature region has a temperature exceeding the third preset temperature t3. If the temperature of any of the electrode units 33 in the non-overtemperature region does not exceed the third preset temperature t3, execute step 833. If any of the electrode units 33 in the non-overtemperature region has a temperature exceeding the third preset temperature t3, execute step 834.

[0334] Step 833: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 by reducing the voltage or current amplitude of the currently applied alternating electrical signal and execute step 835;

[0335] Step 834: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature region of the electrode sheet 13 in a manner that further reduces the voltage or current amplitude of the currently applied alternating electrical signal and execute step 835;

[0336] Step 835: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to re-acquire the temperature of each electrode unit 33 of the electrode sheet 13 and selecting to execute step 836 or step 838. The temperature of each electrode unit 33 of the electrode sheet 13 includes the temperature of each electrode unit 33 in the over-temperature area and the temperature of each electrode unit 33 in the non-over-temperature area.

[0337] Step 836: Determine whether the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1. If the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1, execute step 837. If the temperature of each electrode unit 33 in the over-temperature area exceeds the first preset temperature t1, return to step 835.

[0338] Step 837: re-determine the area as a non-overtemperature area and execute step 838;

[0339] Step 838: Determine whether the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1. If the temperatures of the electrode units 33 in the non-overtemperature area do not exceed the first preset temperature t1, execute step 839. If any of the temperatures of the electrode units 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 840.

[0340] Step 839: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 812;

[0341] Step 840: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the second preset temperature t2, execute step 841. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the second preset temperature t2, execute step 842.

[0342] Step 841: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area in a manner that maintains the voltage or current amplitude of the currently applied alternating electrical signal unchanged and return to step 812;

[0343] Step 842: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the third preset temperature t3. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the third preset temperature t3, execute step 843. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the third preset temperature t3, execute step 844.

[0344] Step 843: Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area by reducing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 812;

[0345] Step 844: Determine whether the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the preset temperature threshold t0. If the temperatures of the electrode units 33 in the non-overtemperature region do not exceed the preset temperature threshold t0, execute step 845. If any of the temperatures of the electrode units 33 in the non-overtemperature region exceeds the preset temperature threshold t0, return to step 821.

[0346] Step 845 : Continue applying the alternating electrical signal to each electrode unit 33 in the non-overtemperature area in a manner of further reducing the voltage or current amplitude of the currently applied alternating electrical signal and return to step 812 .

[0347] The process of combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 811 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet is specifically as follows:

[0348] Disconnect all control switches 54 electrically connected to the corresponding electrode sheets 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 to the end that applies an alternating electrical signal to each electrode unit 33; or

[0349] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the alternating power line 57; or

[0350] All control switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective two ends.

[0351] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in steps 812, 824, and 835 is specifically as follows:

[0352] Controlling the power supply switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switches 55 electrically connected to the electrode sheet 13 to switch in time-sharing order from the end at which the alternating electric signal is applied to each electrode unit 33 to the end at which the temperature of each electrode unit 33 is collected, and controlling the remaining two-way switches 55 to switch in time-sharing order from the end at which the temperature of each electrode unit 33 is collected to the end at which the alternating electric signal is applied to each electrode unit 33, and closing the control switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in time-sharing order to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0353] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switches 55 electrically connected to the electrode sheet 13 to switch from both ends thereof, through which the alternating electric signal is applied to each electrode unit 33, to one end thereof in a time-sharing manner, and controlling the remaining two-way switches 55 to switch from one end thereof to both ends thereof, through which the alternating electric signal is applied to each electrode unit 33, and closing the control switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0354] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switches 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52, and controlling the remaining two-way switches 55 to switch the electrode sheet 13 from being electrically connected to the corresponding ADC unit 52 to being electrically connected to the alternating power line 57, and closing the control switches 54 electrically connected to the electrode units 33 of the electrode sheet 13 in a time-divisional and sequential manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0355] The power supply switch 40 of the electric field generator 30 is controlled to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, and each of the two-way switching switches 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating electric signal to transmitting a direct current signal or a temperature detection signal in a time-sharing sequence. The remaining two-way switching switches 55 switch from transmitting a direct current signal or a temperature detection signal to transmitting an alternating electric signal, and close the control switches 54 electrically connected to each electrode unit 33 of the electrode sheet 13 in a time-sharing sequence to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0356] The first preset temperature in steps 813, 825, 828, 836, and 838 is 40°C to 40.3°C, preferably 40.2°C. The second preset temperature in steps 815, 830, and 840 is 40.4°C to 40.6°C, preferably 40.5°C. The third preset temperature in steps 817, 832, and 842 is 40.7°C to 40.9°C, preferably 40.8°C. The preset temperature threshold in steps 819 and 844 is 41°C to 41.5°C, preferably 41°C. The preset quantity threshold in step 822 is preferably 2.

[0357] The process of continuing to apply the alternating electrical signal in step 814, step 816, step 818, step 820, step 829, step 831, step 833, step 834, step 839, step 841, step 843, and step 845 is specifically as follows:

[0358] disconnecting the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time controlling the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied to connect the alternating electric signal transmission path electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to continue to be applied; or

[0359] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied to switch from its respective terminal 1 to its respective terminal 2 so as to continue to apply the alternating electrical signal to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied; or

[0360] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied, and at the same time control the two-way switch 55 electrically connected to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied, so that both ends of each of the two-way switch 55 are electrically connected to the alternating power line 57 so as to continue to apply the alternating electrical signal to the electrode unit 33 to which the alternating electrical signal needs to continue to be applied; or

[0361] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied so that its two ends are closed and one end is disconnected, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to continue to be applied; or

[0362] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied so that the electrode unit 33 to which the alternating electric signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the alternating electric signal.

[0363] The method of increasing the voltage or current amplitude of the currently applied alternating electric signal in step 814, step 829, and step 839 is to continue applying the alternating electric signal by boosting the currently applied alternating electric signal with a DC voltage amplitude increment of 0.03V per second and then continuing to apply the alternating electric signal.

[0364] Continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal as described in step 818, step 820, step 833, step 834, step 843 and step 845 specifically means continuing to apply the alternating electric signal in a manner of 5V less than the voltage amplitude of the currently applied alternating electric signal and for 3 minutes.

[0365] The process of stopping applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 in step 823 is specifically as follows:

[0366] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the alternating power line 57; or

[0367] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch from the end where the alternating electrical signal is applied to each electrode unit 33 to the end where the temperature of each electrode unit 33 is collected; or

[0368] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all two ends of the bidirectional switch 55, which apply alternating electrical signals to each electrode unit 33, to one end; or

[0369] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from electrically connecting each electrode unit 33 with the alternating power line 57 to electrically connecting each electrode unit 33 with the corresponding ADC unit 52; or

[0370] The bidirectional switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0371] The process of stopping applying the alternating electrical signal to each electrode unit 33 in the over-temperature area in step 827 is specifically as follows:

[0372] Control the bidirectional switch 55 electrically connected to the electrode units 33 in the over-temperature area to disconnect the electrical connection between the electrode units 33 in the over-temperature area and the alternating power line 57; or

[0373] Control the bidirectional switches 55 electrically connected to the electrode units 33 in the over-temperature zone to switch all ends thereof from the end where the electrode units 33 in the over-temperature zone are applied with alternating electrical signals to the end where the electrode units 33 in the over-temperature zone are subjected to temperature acquisition; or

[0374] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature zone to switch all two ends of the bidirectional switch 55, which applies an alternating electrical signal to each electrode unit 33 in the over-temperature zone, to one end; or

[0375] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area so that each electrode unit 33 in the over-temperature area switches from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52; or

[0376] The bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area is controlled to switch each electrode unit 33 in the over-temperature area from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0377] When the tumor electric field therapy system 100 is in a standby state before starting work, no alternating electric signal is applied to the electrode unit 33. The first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the switching timing of each bidirectional switching switch 55 and each control switch 54, so that the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to each row of electrode units 33 (33-1 to 33-20) in turn.

[0378] The first controller 51 receives the temperature detection signal of the temperature detection unit 35 corresponding to each electrode unit 33 (33-1 to 33-20) through the ADC unit 52, and transmits it to the AC signal generator 39 of the electric field generator 30 through the first communication unit 56 and the second communication unit 38, and then controls or adjusts the alternating electric signal applied to each electrode unit 33 through the second controller 37.

[0379] While various operations are depicted in the drawings as following a particular order, this should not be understood as requiring that these operations be performed in the particular order shown or in sequential order, nor should it be understood that all illustrated operations must be performed to achieve desirable results.

[0380] Example 2:

[0381] In the tumor electric field therapy system 100 shown in Example 1, some adjacent electrode units 33 in the electrode sheet 13 are connected by connecting strips (not numbered). The connection method of the 10 electrode units 33 on the left side of the electrode sheet 13 is asymmetrical to the connection method of the 10 electrode units 33 on the right side. The 10 electrode units 33 on the left side of the electrode sheet 13 have 4 electrode units 33 at the free ends, and the 10 electrode units 33 on the right side of the electrode sheet 13 have 5 electrode units 33 at the free ends. Different from the tumor electric field therapy system 100 shown in Example 1, the reference Figure 17 , another tumor electric field therapy system 100A is described below. Its main concept is the same as the above-mentioned tumor electric field therapy system 100, and the spatial arrangement of its electrode units 33A is the same as the spatial arrangement of the electrode units 33 of the tumor electric field therapy system 100 shown in Example 1. The difference is that: the connection method of the electrode units 33A in the electrode sheet 13A of the tumor electric field therapy system 100A is different, the connection method of the 10 electrode units 33A on the left side of the electrode sheet 13A and the connection method of the 10 electrode units 33A on the right side are symmetrical, the 10 electrode units 33A on the left side of the electrode sheet 13A have 4 electrode units 33A at the free ends, and the 10 electrode units 33A on the right side of the electrode sheet 13A have 4 electrode units 33A at the free ends. Specifically, along the columns upward, only the adjacent two electrode units 33 in the third and fourth columns are connected by a connecting strip (unnumbered), and the adjacent two electrode units 33 in the other four columns are not connected by a connecting strip. The bridging portion (unnumbered) connects the two connecting strips (unnumbered) facing each other upward in the columns.

[0382] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 1 and will not be repeated here.

[0383] Example 3:

[0384] In the tumor electric field therapy system 100 shown in Example 1, each electrode sheet 13 includes 20 electrode units 33. Figure 18 and Figure 19, the following describes another tumor electric field therapy system 100B. Its main concept is the same as that of the above-mentioned tumor electric field therapy system 100, with the following differences: each electrode sheet 13B of the tumor electric field therapy system 100B includes 13 electrode units 33B, each electrode sheet 13B does not have an electrode unit 33B at a free end, and the number of electrode units 33B included in each row group and each column group of each electrode sheet 13B is different. Specifically, these 13 electrode units 33B are arranged in a spatial structure according to five rows and five columns. The first and fifth rows each include two electrode units 33B, and the two electrode units 33B in each row are located in the second and fourth columns respectively; the second to fourth rows each include three electrode units 33B, and the three electrode units 33B in each row are located in the first, third, and fifth columns respectively. Each adjacent pair of electrode units 33B in each of the five rows of electrode units 33B is connected by a connecting strip (unnumbered). Each adjacent pair of electrode units 33B in each of the first, third, and fifth columns is connected by a connecting strip (unnumbered). The electrode unit 33B in the second column of the first row is connected to the electrode units 33B in the first column of the second row and the third column of the first row, respectively, by a connecting strip (unnumbered); the electrode unit 33B in the fourth column of the first row is connected to the electrode units 33B in the third column of the second row and the fifth column of the first row, respectively, by a connecting strip (unnumbered); the electrode unit 33B in the second column of the fifth row is connected to the electrode units 33B in the first column of the fourth row and the third column of the fourth row, respectively, by a connecting strip (unnumbered); the electrode unit 33B in the fourth column of the fifth row is connected to the electrode units 33B in the third column of the fourth row and the fifth column of the fourth row, respectively, by a connecting strip (unnumbered).

[0385] Figure 19 for Figure 18 The diagram shows the circuit connection between the electrode sheet 13B and the adapter 20B of the tumor electric field therapy system 100B. The multiple electrode units 33B are arranged into multiple row groups and multiple column groups in terms of circuit connection. In this embodiment, each electrode sheet 13B is provided with 13 electrode units 33B. The 13 electrode units 33B are arranged in the order of 1 to 13 in terms of circuit connection. The electrode units 33-1B to 33-13B are divided into three row groups and five column groups. That is, the 13 electrode units 33B are arranged in three rows and five columns in terms of circuit connection. The first and second row groups each include five electrode units 33B, the third row group includes three electrode units 33B, the first through third column groups each include three electrode units 33B, and the fourth through fifth column groups each include two electrode units 33B.

[0386] Electrode sheet 13B includes five grounding lines 18B: a first grounding line 18-1B, a second grounding line 18-2B, a third grounding line 18-3B, a fourth grounding line 18-4B, and a fifth grounding line 18-5B. Each of the five grounding lines 18B corresponds to one of the five column groups. The first column group includes electrode unit 33-1B, electrode unit 33-6B, and electrode unit 33-11B; the second column group includes electrode unit 33-2B, electrode unit 33-7B, and electrode unit 33-12B; the third column group includes electrode unit 33-3B, electrode unit 33-8B, and electrode unit 33-13B; the fourth column group includes electrode unit 33-4B and electrode unit 33-9B; and the fifth column group includes electrode unit 33-5B and electrode unit 33-10B. Specifically, the first grounding line 18-1B is used to ground the grounding end 35-1B of the temperature detection unit 35B corresponding to the electrode unit 33-1B, the electrode unit 33-6B, and the electrode unit 33-11B in the first column group; the second grounding line 18-2B is used to ground the grounding end 35-1B of the temperature detection unit 35B corresponding to the electrode unit 33-2B, the electrode unit 33-7B, and the electrode unit 33-12B in the second column group; the third grounding line 18-3B is used to ground the electrode unit 33-3B in the third column group. The grounding ends 35-1B of the corresponding temperature detection units 35B of the electrode units 33-3B, electrode units 33-8B, and electrode units 33-13B are grounded; the fourth grounding wire 18-4B is used to ground the grounding ends 35-1B of the corresponding temperature detection units 35B of the electrode units 33-4B and electrode units 33-9B in the fourth column group; the fifth grounding wire 18-5B is used to ground the grounding ends 35-1B of the corresponding temperature detection units 35B of the electrode units 33-5B and electrode units 33-10B in the fifth column group.

[0387] Unlike the above-mentioned embodiment 1 or embodiment 2, the multi-channel dual-purpose signal line 19B of this embodiment includes only three dual-purpose signal lines, namely the first dual-purpose signal line 19-1B, the second dual-purpose signal line 19-2B, and the third dual-purpose signal line 19-3B. The first dual-purpose signal line 19-1B, the second dual-purpose signal line 19-2B, and the third dual-purpose signal line 19-3B are respectively arranged in a one-to-one correspondence with the three row groups of electrode units 33B of the electrode sheet 13B. Specifically, the five electrode units 33B from electrode unit 33-1B to electrode unit 33-5B are connected in series and then connected to the first dual-purpose signal line 19-1B, and the temperature detection units 35B corresponding to the five electrode units 33 from electrode unit 33-1B to electrode unit 33-5B are connected in series and then connected to the first dual-purpose signal line 19-1B; the five electrode units 33B from electrode unit 33-6B to electrode unit 33-10B are connected in series and then connected to the second dual-purpose signal line 19-2B, and the electrode units 33- The temperature detection units 35B corresponding to the five electrode units 33B, from electrode unit 33-6B to electrode unit 33-10B, are connected in series and then connected to the second dual-purpose signal line 19-2B. The three electrode units 33B, from electrode unit 33-11B to electrode unit 33-13B, are connected in series and then connected to the third dual-purpose signal line 19-3B. Furthermore, the temperature detection units 35B corresponding to the three electrode units 33, from electrode unit 33-11B to electrode unit 33-13B, are connected in series and then connected to the third dual-purpose signal line 19-3B. Of course, in some examples, the multiplexed dual-purpose signal line 19B may also include four dual-purpose signal lines, wherein the fourth dual-purpose signal line is not electrically connected to the signal terminal of any temperature detection unit.

[0388] Specifically, in this embodiment, the plurality of control switches 54B in the corresponding group of control switches 54B are respectively a first control switch 54-1B, a second control switch 54-2B, a third control switch 54-3B, a fourth control switch 54-4B, and a fifth control switch 54-5B. The first control switch 54-1B, the second control switch 54-2B, the third control switch 54-3B, the fourth control switch 54-4B, and the fifth control switch 54-5B respectively control the closing or opening of the corresponding ground line 18B of the same electrode sheet 13B. The first control switch 54-1B is used to control the closing or disconnection of the first grounding line 18-1B of the corresponding electrode sheet 13B, and can cooperate with the corresponding group of two-way switching switches 55B to control the power on and off of each temperature detection unit 35B corresponding to the three electrode units 33B in the first column group of the electrode sheet 13B, namely, the electrode unit 33-1B, the electrode unit 33-6B, and the electrode unit 33-11B; the second control switch 54-2B is used to control the closing or disconnection of the second grounding line 18-2B of the electrode sheet 13B, and can cooperate with the corresponding group of two-way switching switches 55B to control the multiple electrode units in the first column group and the second column group of the electrode sheet 13B (the multiple electrode units can be: electrode unit 33-1B and electrode unit 33-2B). B, electrode unit 33-6B and electrode unit 33-7B, electrode unit 33-11B and electrode unit 33-12B) corresponding temperature detection units 35B are powered on and off; the third control switch 54-3B is used to control the closing or opening of the third grounding line 18-3B of the electrode sheet 13B, and then can cooperate with the corresponding group of bidirectional switching switches 55B to control the power on and off of each temperature detection unit 35B corresponding to multiple electrode units (electrode units 33-1B to 33-3B, electrode units 33-6B to 33-8B, electrode units 33-11B to 33-13B) in the first column group, second column group and third column group of the electrode sheet 13B; the same applies to the fourth control switch 54-4B and the fifth control switch 54-5B.

[0389] Taking the electrical connection between an electrode sheet 13B and an adapter 20B as an example, the multiple bidirectional switches 55B in the corresponding set of bidirectional switches 55B are respectively a first bidirectional switch 55-1B, a second bidirectional switch 55-2B, a third bidirectional switch 55-3B, and a fourth bidirectional switch 55-4B. The first bidirectional switch 55-1B, the second bidirectional switch 55-2B, and the third bidirectional switch 55-3B respectively control the switching of a corresponding one of the multiplexed dual-purpose signal lines 19B of the same electrode sheet 13B between transmitting an alternating electrical signal and transmitting a temperature detection signal. Specifically, the first bidirectional switch 55-1B is used to control the switching of the first dual-purpose signal line 19-1B of the corresponding electrode sheet 13B between transmitting alternating electrical signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of each electrode unit 33B from the electrode unit 33-1B to the electrode unit 33-5B in the first row group of the electrode sheet 13B and the conduction of the signal end 35-2B of each temperature detection unit 35B corresponding to the electrode unit 33-1B to the electrode unit 33-5B in the first row group, and cooperating with the corresponding first control switch 54-1B, the second control switch 54-2B, the third control switch 54-3B, the fourth control switch 54-4B, and the fifth control switch 54-5B, so that the first row of electrode units 33-1B to the electrode unit 33-5B transmits the alternating electrical signal to the patient or the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35B corresponding to these electrode units 33B are sampled and output to the corresponding ADC unit 52B. The second bidirectional switch 55-2B is used to control the switching between the transmission of the alternating electrical signal and the transmission of the temperature detection signal by the second dual-purpose signal line 19-2B of the corresponding electrode sheet 13B, thereby controlling the switching between the conduction of the electrode units 33B from the electrode unit 33-6B to the electrode unit 33-10B in the second row group of the electrode sheet 13B and the conduction of the signal ends 35-2B of the temperature detection units 35B corresponding to the electrode units 33-6B to the electrode units 33-10B in the second row group, and cooperates with the corresponding first control switch 54-1B, second control switch 54-2B, third control switch 54-3B, fourth control switch 54-4B, and fifth control switch 54-5B to enable the second row electrode units 33-6B to the electrode units 33-10B to transmit the alternating electrical signal to the patient or to enable the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35B corresponding to the electrode units 33B to be sampled and output to the corresponding ADC unit 52B.The third bidirectional switch 55-3B is used to control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal by the third dual-purpose signal line 19-3B of the corresponding electrode sheet 13B, thereby controlling the switching between the conduction from the electrode unit 33-11B in the third row group of the electrode sheet 13B to the electrode unit 33-13B and the conduction from the electrode unit 33-11B in the third row group to the signal end 35-2B of each temperature detection unit 35B corresponding to the electrode unit 33-13B, and communicating with the corresponding first control switch 54-1B. The second control switch 54-2B and the third control switch 54-3B cooperate to enable the third row of electrode units 33-11B to 33-13B to transmit alternating electrical signals to the patient, or to enable the temperature detection signals detected by one or more combinations of the temperature detection units 35B corresponding to these electrode units 33B to be sampled and output to the corresponding ADC units. The fourth bidirectional switch 55-4B does not correspond to any row group (not connected to any dual-purpose signal line), so signal control through the fourth bidirectional switch 55-4B is not required.

[0390] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 1 and will not be repeated here.

[0391] Example 4:

[0392] In the tumor therapy field system 100B shown in Example 3, the electrode units 33B at the end of the 13 electrode units 33B in each electrode sheet 13B are not freely arranged. Figure 20 Another tumor therapy field system 100C has the same main concept as the aforementioned tumor therapy field system 100B, with the following differences: the connection method of the connecting strips (unnumbered) in the electrode sheet 13C of this tumor therapy field system 100C is different, and the 13 electrode units 33C include two electrode units 33C at the free ends. Specifically, Figure 20 In the illustrated electrode sheet 13C of the tumor therapy field system 100C, no connecting bands are provided between the electrode unit 33C in the first row, second column and the two electrode units 33C in the first row, fourth column and the second row, first column; no connecting bands are provided between the electrode unit 33C in the fifth row, fourth column and the two electrode units 33C in the fifth row, second column and the fourth row, fifth column; no connecting bands are provided between the two electrode units 610 in the second row, fifth column and the third row, fifth column; and no connecting bands are provided between the two electrode units 610 in the second row, fifth column and the third row, fifth column. The connecting bands (not shown) of the electrode sheet 100C are arranged in this way to create corresponding open spaces and free ends, facilitating application.

[0393] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 3 and will not be repeated here.

[0394] Example 5:

[0395] In the tumor electric field therapy system 100B shown in Example 3, the 13 electrode units 33 in each electrode sheet 13B are connected by 22 connecting strips. Figure 21 Another tumor therapy field system 100D has the same main concept as the tumor therapy field system 100B, except that the 13 electrode units 33D in each electrode sheet 13D of the tumor therapy field system 100D are connected by 18 connecting strips. Specifically, Figure 21 In the illustrated electrode sheet 13D of the tumor therapy field system 100D, no connecting strips are provided between adjacent electrode units 33D in the first and fifth rows; no connecting strips are provided between adjacent electrode units 33D in the second row, first column, and second row, third column; and no connecting strips are provided between adjacent electrode units 33D in the fourth row, third column, and fourth row, fifth column. This arrangement of connecting strips (not shown) in the electrode sheet 100D creates open spaces and free ends for easier application.

[0396] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 3 and will not be repeated here.

[0397] Example 6:

[0398] The difference from the tumor electric field treatment system 100B shown in Example 3 is that Figure 22 Another tumor electric field therapy system 100E is described below. Its main concept is the same as that of the above-mentioned tumor electric field therapy system 100B, except that: each electrode sheet 13E of the tumor electric field therapy system 100E has different numbers of electrode units 33E included in each row group and each column group in the circuit connection.

[0399] Figure 22This is a schematic diagram of the circuit connection between the electrode sheet 13E and the adapter 20E of the tumor electric field therapy system 100E. The multiple electrode units 33E are arranged into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13E is provided with 13 electrode units 33E. The 13 electrode units 33E are arranged in the order of 1 to 13 in the circuit connection. Electrode units 33-1E through 33-13E are divided into four row groups and four column groups. That is, the 13 electrode units 33E are arranged in four rows and four columns in the circuit connection. Each row of the first through third row groups includes four electrode units 33E, and the fourth row group includes one electrode unit 33E. The first column group includes four electrode units 33E, and the second through fourth column groups each include three electrode units 33E.

[0400] The electrode sheet 13E includes four grounding lines 18E: a first grounding line 18-1E, a second grounding line 18-2E, a third grounding line 18-3E, and a fourth grounding line 18-4E. The first grounding line 18-1E, the second grounding line 18-2E, the third grounding line 18-3E, and the fourth grounding line 18-4E are respectively arranged in a one-to-one correspondence with the four column groups. Of the four column groups of the electrode sheet 13E, the first column group includes electrode unit 33-1E, electrode unit 33-5E, electrode unit 33-9E, and electrode unit 33-13E; the second column group includes electrode unit 33-2E, electrode unit 33-6E, and electrode unit 33-10E; the third column group includes electrode unit 33-3E, electrode unit 33-7E, and electrode unit 33-11E; and the fourth column group includes electrode unit 33-4E, electrode unit 33-8E, and electrode unit 33-12E. Specifically, the first grounding wire 18-1E is used to ground the grounding ends 35-1E of the temperature detection units 35E corresponding to the electrode units 33-1E, 33-5E, 33-9E, and 33-13E in the first column group; the second grounding wire 18-2E is used to ground the grounding ends 35-1E of the temperature detection units 35E corresponding to the electrode units 33-2E, 33-6E, and 33-10E in the second column group; the third grounding wire 18-3E is used to ground the grounding ends 35-1E of the temperature detection units 35E corresponding to the electrode units 33-3E, 33-7E, and 33-11E in the third column group; the fourth grounding wire 18-4E is used to ground the grounding ends 35-1E of the temperature detection units 35E corresponding to the electrode units 33-4E, 33-8E, and 33-12E in the fourth column group. Of course, in some examples, the multiple ground lines 18E may also include five ground lines, wherein the fifth ground line is not electrically connected to the ground terminal of any temperature detection unit, that is, the fifth ground line does not short-circuit each corresponding temperature detection unit in any column group to ground.

[0401] In this embodiment, the multiplexed dual-purpose signal line 19E includes a first dual-purpose signal line 19-1E, a second dual-purpose signal line 19-2E, a third dual-purpose signal line 19-3E, and a fourth dual-purpose signal line 19-4E, which are respectively arranged in a one-to-one correspondence with the four row groups of electrode units 33E of the electrode sheet 13E. Specifically, the four electrode units 33E from electrode unit 33-1E to electrode unit 33-4E are connected in series to the first dual-purpose signal line 19-1E, and the four electrode units 33E from electrode unit 33-1E to electrode unit 33-4E and their corresponding temperature detection units 35E are connected in series to the first dual-purpose signal line 19-1E; the four electrode units 33E from electrode unit 33-6E to electrode unit 33-8E are connected in series to the second dual-purpose signal line 19-2E, and the four electrode units 33E from electrode unit 33-5E to electrode unit 33-8E and their corresponding temperature detection units The electrode units 35E are connected in series and connected to the second dual-purpose signal line 19-2E; the four electrode units 33E from the electrode unit 33-9E to the electrode unit 33-12E are connected in series and connected to the third dual-purpose signal line 19-3E, and the four electrode units 33E from the electrode unit 33-9E to the electrode unit 33-12E and their respective corresponding temperature detection units 35E are connected in series and connected to the third dual-purpose signal line 19-3E; the electrode unit 33-13E is connected to the fourth dual-purpose signal line 19-4E, and the temperature detection unit 35E corresponding to the electrode unit 33-13E is connected to the fourth dual-purpose signal line 19-4E.

[0402] Specifically, in this embodiment, the plurality of control switches 54E in the corresponding group of control switches 54E are respectively a first control switch 54-1E, a second control switch 54-2E, a third control switch 54-3E, a fourth control switch 54-4E, and a fifth control switch 54-5E. The first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, and the fourth control switch 54-4E respectively control the closing or opening of the corresponding ground line 18E of the same electrode sheet 13E. The first control switch 54-1E is used to control the closing or disconnection of the first grounding line 18-1E of the corresponding electrode sheet 13E, and can cooperate with the corresponding group of two-way switching switches 55E to control the power on and off of each temperature detection unit 35E corresponding to the four electrode units 33E in the first column group of the electrode sheet 13E, namely, the electrode unit 33-1E, the electrode unit 33-5E, the electrode unit 33-9E, and the electrode unit 33-13E; the second control switch 54-2E is used to control the closing or disconnection of the second grounding line 18-2E of the electrode sheet 13E, and can cooperate with the corresponding group of two-way switching switches 55E to control the multiple electrode units in the first column group and the second column group of the electrode sheet 13E (the multiple electrode units can be: electrode unit 33-1E and electrode unit 33-2E, electrode unit 33-5E and electrode unit 33-6 E, electrode unit 33-9E and electrode unit 33-10E) corresponding temperature detection unit 35E is powered on and off; the third control switch 54-3E is used to control the closing or opening of the third grounding line 18-3E of the electrode sheet 13E, and then can cooperate with the corresponding group of two-way switching switches 55E to control the power on and off of each temperature detection unit 35E corresponding to multiple electrode units in the first column group, second column group and third column group of the electrode sheet 13E (the multiple electrode units can be respectively: electrode unit 33-1E to electrode unit 33-3E, electrode unit 33-5E to electrode unit 33-7E, electrode unit 33-9E to electrode unit 33-11E); the fourth control switch 54-4E is the same; the fifth control switch 54-5E is not connected to any grounding line, and the fifth control switch 54-5E is not used for signal control.

[0403] Taking the electrical connection between an electrode sheet 13E and an adapter 20E as an example, the multiple bidirectional switches 55E in the corresponding set of bidirectional switches 55E are respectively a first bidirectional switch 55-1E, a second bidirectional switch 55-2E, a third bidirectional switch 55-3E, and a fourth bidirectional switch 55-4E. The first bidirectional switch 55-1E, the second bidirectional switch 55-2E, the third bidirectional switch 55-3E, and the fourth bidirectional switch 55-4E respectively control the switching of a corresponding one of the multiplexed dual-purpose signal lines 19E of the same electrode sheet 13E between transmitting an alternating electrical signal and transmitting a temperature detection signal. Specifically, the first bidirectional switch 55-1E is used to control the switching of the first dual-purpose signal line 19-1E of the corresponding electrode sheet 13E between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of each electrode unit 33E of the electrode unit 33-1E to the electrode unit 33-4E in the first row group of the electrode sheet 13E and the conduction of the signal end 35-2E of each temperature detection unit 35E corresponding to the electrode unit 33-1E to the electrode unit 33-4E in the first row group, and cooperates with the corresponding first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, and the fourth control switch 54-4E to enable the first row of electrode units 33-1E to the electrode unit 33-4E to transmit the alternating electric signal to the patient or enable the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35E corresponding to these electrode units 33E to be sampled and output to the corresponding ADC unit 54-1E, the second control switch 54-2E, the third control switch 54-3E, and the fourth control switch 54-4E. 2E; the second bidirectional switch 55-2E is used to control the switching of the second dual-purpose signal line 19-2E of the corresponding electrode sheet 13E between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of each electrode unit 33E from the electrode unit 33-5E to the electrode unit 33-8E in the second row group of the electrode sheet 13E and the conduction of the signal end 35-2E of each temperature detection unit 35E corresponding to the electrode unit 33-5E to the electrode unit 33-8E in the second row group, and cooperates with the corresponding first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, and the fourth control switch 54-4E to enable the second row electrode unit 33-5E to the electrode unit 33-8E to transmit the alternating electric signal to the patient or to enable the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35E corresponding to the electrode units 33E to be sampled and output to the corresponding ADC unit 52E;The third bidirectional switch 55-3E is used to control the switching of the third dual-purpose signal line 19-3E of the corresponding electrode sheet 13E between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of each electrode unit 33E from the electrode unit 33-9E to the electrode unit 33-12E in the third row group of the electrode sheet 13E and the conduction of the signal end 35-2E of each temperature detection unit 35E corresponding to the electrode unit 33-9E to the electrode unit 33-12E in the third row group, and cooperates with the corresponding first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, and the fourth control switch 54-4E to enable the third row electrode unit 33-9E to the electrode unit 33-12E to transmit the alternating electric signal to the patient or enable the corresponding temperature detection units 35E corresponding to these electrode units 33E to be switched on. The temperature detection signals detected by one or more combinations are sampled and output to the corresponding ADC unit 52E. The fourth bidirectional switch 55-4E is used to control the switching between the transmission of the alternating electrical signal and the transmission of the temperature detection signal by the fourth dual-purpose signal line 19-4E of the corresponding electrode sheet 13E. This, in turn, controls the switching between the conduction of the electrode units 33-13E in the fourth row of the electrode sheet 13E and the conduction of the signal terminals 35-2E of the temperature detection units 35E corresponding to the electrode units 33-13E in the fourth row. It cooperates with the corresponding first control switch 54-1E to cause the fourth row of electrode units 33-13E to transmit the alternating electrical signal to the patient or to cause the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35E corresponding to the electrode units 33E to be sampled and output to the corresponding ADC unit 52E.

[0404] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 3 and will not be repeated here.

[0405] Example 7:

[0406] The difference from the tumor electric field treatment system 100E shown in Example 6 is that Figure 23 Another tumor electric field therapy system 100F is described below. Its main concept is the same as that of the above-mentioned tumor electric field therapy system 100E, except that each electrode sheet 13E of the tumor electric field therapy system 100F has different numbers of electrode units 33F included in each row group and each column group in the circuit connection.

[0407] Figure 23This is a schematic diagram of the circuit connection between the electrode sheet 13F and the adapter 20F of the tumor electric field therapy system 100F. The multiple electrode units 33F are arranged into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13F is provided with 13 electrode units 33F. The 13 electrode units 33F are arranged in the order of 1 to 13 for circuit connection. Electrode units 33-1F through 33-13F are divided into four row groups and four column groups. That is, the 13 electrode units 33F are arranged in four rows and four columns for circuit connection. The first row group includes four electrode units 33F, the second through fourth row groups each include three electrode units 33F, the first through third column groups each include four electrode units 33F, and the fourth column group includes one electrode unit 33F.

[0408] The electrode sheet 13F includes four ground lines 18F, namely a first ground line 18-1F, a second ground line 18-2F, a third ground line 18-3F, and a fourth ground line 18-4F. The first ground line 18-1F, the second ground line 18-2F, the third ground line 18-3F, and the fourth ground line 18-4F are respectively provided in a one-to-one correspondence with the four column groups. Of course, in some examples, the multiple ground lines 18F may also include five ground lines, wherein the fifth ground line is not electrically connected to the ground terminal of any temperature detection unit, that is, the fifth ground line does not short-circuit each corresponding temperature detection unit in any column group to ground. The multiple control switches 54F are respectively a first control switch 54-1F, a second control switch 54-2F, a third control switch 54-3F, a fourth control switch 54-4F, and a fifth control switch 54-5F. The first control switch 54-1F, the second control switch 54-2F, the third control switch 54-3F, and the fourth control switch 54-4F respectively control the closing or opening of the corresponding grounding line 18F of the same electrode sheet 13F. The fifth control switch 54-5F is not connected to any grounding line and is not used for signal control.

[0409] The multiplexed signal lines 19F include four dual-purpose signal lines: a first dual-purpose signal line 19-1F, a second dual-purpose signal line 19-2F, a third dual-purpose signal line 19-3F, and a fourth dual-purpose signal line 19-4F. These lines correspond one to each of the four row groups of the electrode unit 33F. The multiplexed signal lines 19F include a first dual-purpose signal line 19-1F, a second dual-purpose signal line 19-2F, a third dual-purpose signal line 19-3F, and a fourth dual-purpose signal line 19-4F. The first, second, third, and fourth dual-purpose switches 55F, 55-1F, 55-2F, 55-3F, and 55-4F, control the switching between transmitting an alternating electrical signal and transmitting a temperature detection signal on a corresponding one of the multiplexed signal lines 19F of the same electrode sheet 13F.

[0410] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 3 and will not be repeated here.

[0411] Example 8:

[0412] The difference from the tumor electric field treatment systems 100B, 100C, 100D, 100E, and 100F shown in Examples 3 to 7 is that Figure 24 and Figure 25 , another tumor electric field therapy system 100G is described below. Its main concept is the same as that of the above-mentioned tumor electric field therapy system 100B, 100C, 100D, 100E or 100F, except that each electrode sheet 13G of the tumor electric field therapy system 100G includes 9 electrode units 33G.

[0413] Figure 25 for Figure 24 FIG. 1 is a schematic diagram showing the circuit connection between the electrode 13G and the adapter 20G of the tumor electric field therapy system 100G.

[0414] The multiple electrode units 33G are arranged into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13G is provided with nine electrode units 33G. The nine electrode units 33G are arranged in the order of 1 to 9 for circuit connection. The electrode units 33-1G to 33-9G are divided into three row groups and four column groups. That is, the nine electrode units 33G are arranged in three rows and four columns for circuit connection. Each row of the first to second row groups includes four electrode units 33G, and the third row group includes one electrode unit 33G. The first column group includes three electrode units 33G, and each column of the second to fourth column groups includes two electrode units 33G.

[0415] The electrode sheet 13G includes four ground lines 18G, namely a first ground line 18-1G, a second ground line 18-2G, a third ground line 18-3G, and a fourth ground line 18-4G. The first ground line 18-1G, the second ground line 18-2G, the third ground line 18-3G, and the fourth ground line 18-4G are respectively provided in a one-to-one correspondence with the four column groups of the electrode unit 33G. Of course, in some examples, the multiple ground lines 18G can also include five ground lines, wherein the fifth ground line is not electrically connected to the ground terminal of any temperature detection unit, that is, the fifth ground line does not short-circuit each corresponding temperature detection unit in any column group to ground. The multiple control switches 54G are respectively a first control switch 54-1G, a second control switch 54-2G, a third control switch 54-3G, a fourth control switch 54-4G, and a fifth control switch 54-5G. The first control switch 54-1G, the second control switch 54-2G, the third control switch 54-3G, and the fourth control switch 54-4G respectively control the closing or opening of the corresponding grounding line 18G of the same electrode sheet 13G. The fifth control switch 54-5G is not connected to any grounding line and is not used for signal control.

[0416] The multiplexed signal lines 19G include three dual-purpose signal lines, namely a first dual-purpose signal line 19-1G, a second dual-purpose signal line 19-2G, and a third dual-purpose signal line 19-3G. The first dual-purpose signal line 19-1G, the second dual-purpose signal line 19-2G, and the third dual-purpose signal line 19-3G are respectively arranged in a one-to-one correspondence with the three row groups of electrode units 33G. Of course, in some examples, the multiplexed signal lines 19G may also include four dual-purpose signal lines, wherein the fourth dual-purpose signal line is not electrically connected to the signal terminal of any temperature detection unit. The multiple bidirectional switches 55G are respectively a first bidirectional switch 55-1G, a second bidirectional switch 55-2G, a third bidirectional switch 55-3G, and a fourth bidirectional switch 55-4G. The first bidirectional switch 55-1G, the second bidirectional switch 55-2G, and the third bidirectional switch 55-3G respectively control the switching of a corresponding dual-purpose signal line 19G in the multiplexed dual-purpose signal line 19G of the same electrode sheet 13G between transmitting alternating electrical signals and transmitting temperature detection signals. The fourth bidirectional switch 55-4G is not connected to any dual-purpose signal line, and the fourth bidirectional switch 55-4G is not used for signal control.

[0417] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 1 and will not be repeated here.

[0418] Example 9:

[0419] The difference from the tumor electric field treatment system 100G shown in Example 8 is that Figure 26Another tumor electric field therapy system 100H is described below. Its main concept is the same as that of the above-mentioned tumor electric field therapy system 100G, except that the number of electrode units 33H included in each row group and column group of the electrode sheet 13H in the circuit connection of each electrode sheet 13H of the tumor electric field therapy system 100H is different.

[0420] Figure 26 FIG. 1 is a schematic diagram showing the circuit connection between the electrode sheet 13H and the adapter 20H of the tumor electric field treatment system 100H.

[0421] The multiple electrode units 33H are arranged into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13H is provided with nine electrode units 33H. The nine electrode units 33H are arranged in the order of 1 to 9 for circuit connection. Electrode units 33-1H to 33-9H are divided into three row groups and three column groups. That is, the nine electrode units 33H are arranged in three rows and three columns for circuit connection. Each row group includes three electrode units 33H, and each column group includes three electrode units 33H.

[0422] The electrode sheet 13H includes three ground lines 18H, namely a first ground line 18-1H, a second ground line 18-2H, and a third ground line 18-3H. The first ground line 18-1H, the second ground line 18-2H, and the third ground line 18-3H are respectively provided in a one-to-one correspondence with the three column groups. Of course, in some examples, the multiple ground lines 18H may also include four or five ground lines, wherein the fourth ground line and / or the fifth ground line are not electrically connected to the ground terminal of any temperature detection unit, that is, the fourth ground line and / or the fifth ground line do not short-circuit each corresponding temperature detection unit in any column group to ground. The multiple control switches 54H are respectively a first control switch 54-1H, a second control switch 54-2H, a third control switch 54-3H, a fourth control switch 54-4H, and a fifth control switch 54-5H. The first control switch 54-1H, the second control switch 54-2H, and the third control switch 54-3H respectively control the closing or opening of the corresponding grounding line 18H of the same electrode sheet 13H. The fourth control switch 54-4H and the fifth control switch 54-5H are not connected to any grounding line, and the fourth control switch 54-4H and the fifth control switch 54-5H are not used for signal control.

[0423] The multiplexed signal lines 19H include three dual-purpose signal lines: a first dual-purpose signal line 19-1H, a second dual-purpose signal line 19-2H, and a third dual-purpose signal line 19-3H. The first dual-purpose signal line 19-1H, the second dual-purpose signal line 19-2H, and the third dual-purpose signal line 19-3H are respectively provided in a one-to-one correspondence with the three row groups of the electrode units 33H. Of course, in some examples, the multiplexed signal lines 19H may also include four dual-purpose signal lines, wherein the fourth dual-purpose signal line is not electrically connected to the signal terminal of any temperature detection unit. The multiple bidirectional switches 55H are respectively a first bidirectional switch 55-1H, a second bidirectional switch 55-2H, a third bidirectional switch 55-3H, and a fourth bidirectional switch 55-4H. The first bidirectional switch 55-1H, the second bidirectional switch 55-2H, and the third bidirectional switch 55-3H respectively control the switching of a corresponding dual-purpose signal line 19H in the multiplexed dual-purpose signal line 19H of the same electrode sheet 13H between transmitting alternating electrical signals and transmitting temperature detection signals. The fourth bidirectional switch 55-4H is not connected to any dual-purpose signal line and is not used for signal control.

[0424] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 8 and will not be repeated here.

[0425] Example 10:

[0426] The main concept of the above-mentioned tumor electric field treatment system 100 is that the adapter 20 and the electric field generator 30 are each provided with an alternating power line 57, which controls the synchronous change of the alternating electric signals of all electrode units 33 on an electrode sheet 13, such as the simultaneous increase or decrease of voltage or current. Different alternating electric signals, such as different voltages or currents, cannot be applied simultaneously to electrode units 33 in different rows. Figures 27 to 31 Another tumor therapy field treatment system 100' is described below. Its main concept is the same as that of the aforementioned tumor therapy field treatment system 100, with the following difference: in this tumor therapy field treatment system 100', each row of electrode units 33' on the corresponding electrode sheet 13' in the adapter 20' and the electric field generator 30' is provided with a corresponding alternating power line 57', so that different alternating electrical signals, such as voltages or currents of different magnitudes, can be applied simultaneously to different rows of electrode units 33'.

[0427] Figure 28 FIG. 1 is a circuit connection diagram of an electrode sheet 13 ′, an adapter 20 ′, and an electric field generator 30 ′ of another tumor electric field treatment system 100 ′ according to an embodiment of the present application. Figure 29This is a schematic diagram of another electrode unit 33' according to an embodiment of the present application. The tumor electric field therapy system 100' includes: at least one pair of electrode sheets 13', an adapter 20' connected to the electrode sheets 13', and an electric field generator 30' connected to the adapter 20'.

[0428] The specific structure of the electrode sheet 13 ′ is the same as that of the electrode sheet 13 , and will not be described in detail here.

[0429] The specific structure of the adapter 20' is similar to the above adapter 20, except that: Figure 28 and Figure 30 , the adapter 20' is provided with four alternating current power lines 57' corresponding to each electrode sheet 13'. The four alternating current power lines 57' are provided in a one-to-one correspondence with the four row-group electrode units 33' of each electrode sheet 13'. Each electrode sheet 13' is provided with a corresponding bidirectional switch 55' and a grounding switch 54'. Both ends of the bidirectional switch 55' are electrically connected to a separate alternating current power line 57', so that the tumor electric field treatment system 100' can simultaneously apply different alternating current signals, such as different voltages or currents, to different row-group electrode units 33' in each electrode sheet 13' as needed.

[0430] The specific structure of the electric field generator 30' is similar to the above electric field generator 30, except that: Figure 28 and Figure 31 A power switch 40' is provided for each alternating power line 57' connected between the AC signal generator 39' and the adapter 20' to individually control the on and off of the alternating electrical signal of each row group of electrode units 33' of each electrode sheet 13'.

[0431] Specifically, refer to Figure 28 and Figure 30As shown, the adapter 20' includes: a first controller 51', multiple groups of ADC units 52' connected to the first controller 51', multiple groups of voltage transformers 53' and multiple groups of control switches 54' corresponding to the multiple groups of ADC units 52', multiple groups of bidirectional switches 55' connected to the multiple groups of ADC units 52', a first communication unit 56', multiple alternating power lines 57' connected to each group of bidirectional switches 55', and a first power module 58' connected to the first communication unit 56', the first controller 51', and the multiple groups of ADC units 52'. The first power module 58' provides a DC power supply VCC to the various electronic components of the adapter 20'. The adapter 20' also includes multiple circuit lines (unnumbered), which are electrically connected to the multiple ground lines 18' and the multiple dual-purpose signal lines 19' in the substrate 31' of the corresponding electrode sheet 13' through the first cables 15' of the corresponding electrode sheet 13'. The multiple circuit lines (unnumbered) include multiple different alternating power lines 57' that transmit alternating electrical signals to the corresponding electrode sheets 13' and are electrically connected to the multiplexed signal lines 19' in the substrate 31' of the corresponding electrode sheets 13', multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiplexed signal lines 19' in the substrate 31' of the corresponding electrode sheets 13' and are used to supply power to the temperature detection units 35' of the electrode sheets 13' or transmit the temperature detection signals of the electrode sheets 13', and multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground lines 18' in the substrate 31' of the corresponding electrode sheets 13'. The number L of circuit lines electrically connected between the adapter 20' and one electrode sheet 13' is equal to the sum of the number of rows and columns of the electrode units 33' of the electrode sheet 13'; the number H of circuits electrically connected between the adapter 20' and X electrode sheets 13' is equal to X times the number of circuit lines electrically connected to a single electrode sheet 13', that is, H=XL=X*(M+N). The number of groups of control switches 54' and the number of groups of bidirectional switching switches 55' are both related to the number of electrode sheets 13'. The number of groups of control switches 54' is the same as the number of groups of bidirectional switching switches 55', and is not less than the number of electrode sheets 13'. Optionally, the number of groups of control switches 54' and bidirectional switching switches 55' is the same as the number of electrode sheets 13'.

[0432] For example, each group of control switches 54' is provided with a plurality of control switches 54', and the plurality of control switches 54' are respectively connected to the adapter 20' and are respectively electrically connected to the circuit lines (unnumbered) corresponding to the multi-way grounding lines 18' of the corresponding electrode sheet 13', and are configured to control the conduction or disconnection of the multi-way grounding lines 18'. The circuit lines (unnumbered) of the multi-way grounding lines 18' that are electrically connected to the electrode sheet 13' are grounded at one end close to the control switch 54'. The number of control switches 54' in each group of control switches 54' is related to the number of grounding lines 18' of the substrate 31' of the corresponding electrode sheet 13', and the two are equal in this embodiment. As Figure 28As shown, in this embodiment, the multiple control switches 54' in each group of control switches 54' are respectively a first control switch 54-1', a second control switch 54-2', a third control switch 54-3', a fourth control switch 54-4', and a fifth control switch 54-5'. The multiple control switches 54' in the same group each control the closing or opening of the corresponding ground line 18' of the same electrode sheet 13'. The first control switch 54-1' is used to control the closing or disconnection of the first grounding line 18-1' of the corresponding electrode sheet 13', and can cooperate with the corresponding group of two-way switching switches 55' to control the power on and off of each temperature detection unit 35' corresponding to the four electrode units 33' in the first column group of the electrode sheet 13', namely, the electrode unit 33-1', the electrode unit 33-6', the electrode unit 33-11', and the electrode unit 33-16'; the second control switch 54-2' is used to control the closing or disconnection of the second grounding line 18-2' of the electrode sheet 13', and can cooperate with the corresponding group of two-way switching switches 55' to control the multiple electrode units in the first column group and the second column group of the electrode sheet 13' (the multiple electrode units can be: electrode unit 33-1' and electrode unit 33-2', electrode unit 33-6' and electrode unit 33-7', electrode unit 33 -11' and electrode unit 33-12', electrode unit 33-16' and electrode unit 33-17') corresponding temperature detection unit 35' is powered on and off; the third control switch 54-3' is used to control the closing or disconnection of the third ground line 18-3' of the electrode sheet 13', and can then cooperate with the corresponding group of two-way switching switches 55' to control the power on and off of each temperature detection unit 35' corresponding to multiple electrode units in the first column group, second column group and third column group of the electrode sheet 13' (the multiple electrode units can be respectively: electrode unit 33-1' to electrode unit 33-3', electrode unit 33-6' to electrode unit 33-8', electrode unit 33-11' to electrode unit 33-13', electrode unit 33-16' to electrode unit 33-18'); the same applies to the fourth control switch 54-4' and the fifth control switch 54-5'. The above-mentioned control switch 54' can be a mechanical switch, such as a relay. The control switches 54 ′ may also be electronic switches, and each control switch 54 ′ may be switched on and off by an additional first controller 51 ′.

[0433] In this embodiment, the multiple groups of control switches 54' are all electronic switches. The first controller 51' is in communication connection with the multiple groups of control switches 54', and is used to cyclically control the opening and closing states of the multiple control switches 54' in each group of control switches 54', and then turn on each grounding wire 18' of the multiple grounding wires 18' of the corresponding electrode sheet 13' in turn and cooperate with the switching of the corresponding two-way switching switch 55' to collect the temperature of the patient's body surface detected by all temperature detection units 35' on the electrode sheet 13'. The number of each group of control switches 54' is not less than the number of grounding wires 18' of the substrate 31' of the corresponding electrode sheet 13'. In this embodiment, the number of each group of control switches 54' is the same as the number of grounding wires 18' of the corresponding electrode sheet 13'.

[0434] Each set of bidirectional switches 55' includes multiple bidirectional switches 55'. The multiple bidirectional switches 55' in each set are connected to the adapter 20' and are electrically connected to circuit lines (not numbered) that correspond one-to-one with the multiplexed signal lines 19' of a corresponding electrode sheet 13'. The number of bidirectional switches 55' in each set of bidirectional switches 55' is related to the number of dual-purpose signal lines 19' of the substrate 31' of the corresponding electrode sheet 13', and is greater than or equal to the number of dual-purpose signal lines 19' of the substrate 31' of the corresponding electrode sheet 13'. In this embodiment, the number of bidirectional switches 55' is equal to the number of dual-purpose signal lines 19' of the substrate 31' of the corresponding electrode sheet 13'. Each bidirectional switch 55' has two ends marked 1 and 2. One end of multiple bidirectional switches 55' in the same group is electrically connected to corresponding detection channels of multiple detection channels of a corresponding group of ADC units 52' through temperature sampling points (unnumbered). Both ends of each bidirectional switch 55' in the same group are electrically connected to corresponding different alternating power lines 57', and are configured to control the multiplexed signal line 19' to connect to the corresponding different alternating power lines 57' to transmit alternating electrical signals or to connect to the corresponding detection channel of the corresponding group of ADC units 52' to receive the temperature detection signal output by the temperature detection unit 35'.

[0435] like Figure 28As shown, taking the electrical connection between one electrode sheet 13' and the adapter 20' as an example, in this embodiment having 20 electrode units 33', the multiple bidirectional switches 55' in each group of bidirectional switches 55' are respectively a first bidirectional switch 55-1', a second bidirectional switch 55-2', a third bidirectional switch 55-3', and a fourth bidirectional switch 55-4'. The multiple bidirectional switches 55' in the same group each control a corresponding dual-purpose signal line 19' in the multiplexed dual-purpose signal line 19' of the same electrode sheet 13' to switch between transmitting an alternating electrical signal and transmitting a temperature detection signal. Specifically, the first bidirectional switch 55-1' is used to control the switching of the first dual-purpose signal line 19-1' of the corresponding electrode sheet 13' between transmitting the alternating electric signal output by the alternating power line 57-1' and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33' from the electrode unit 33-1' to the electrode unit 33-5' in the first row group of the electrode sheet 13' and the conduction of the signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-1' to the electrode unit 33-5' in the first row group. By switching between the two and cooperating with the corresponding first control switch 54-1', the second control switch 54-2', the third control switch 54-3', the fourth control switch 54-4', and the fifth control switch 54-5', the first row electrode unit 33-1' to the electrode unit 33-5' transmit a separate alternating electrical signal to the patient or the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35' corresponding to the electrode units 33' are sampled and output to the corresponding ADC unit 52'. The second bidirectional switch 55-2' is used to control the switching of the second dual-purpose signal line 19-2' of the corresponding electrode sheet 13' between transmitting the alternating electric signal output by the alternating power line 57-2' and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33' from the electrode unit 33-6' to the electrode unit 33-10' in the second row group of the electrode sheet 13' and the conduction of the signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-6' to the electrode unit 33-10' in the second row group. The switching between them and cooperating with the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', fourth control switch 54-4', and fifth control switch 54-5', so that the second row electrode units 33-6' to electrode units 33-10' transmit separate alternating electrical signals to the patient or the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35' corresponding to these electrode units 33' are sampled and output to the corresponding ADC unit 52';The third bidirectional switch 55-3' is used to control the switching of the third dual-purpose signal line 19-3' of the corresponding electrode sheet 13' between transmitting the alternating electric signal output by the alternating power line 57-3' and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33' from the electrode unit 33-11' to the electrode unit 33-15' in the third row group of the electrode sheet 13' and the conduction of the signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-11' to the electrode unit 33-15' in the third row group. The switching between them and cooperating with the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', fourth control switch 54-4', and fifth control switch 54-5', so that the third row electrode units 33-11' to electrode units 33-15' transmit separate alternating electrical signals to the patient or the temperature detection signals detected by the corresponding one or more combinations of the temperature detection units 35' corresponding to the electrode units 33' are sampled and output to the corresponding ADC unit 52'; The fourth bidirectional switch 55-4' is used to control the switching of the fourth dual-purpose signal line 19-4' of the corresponding electrode sheet 13' between transmitting the alternating electric signal output by the alternating power line 57-4' and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33' from the electrode unit 33-16' to the electrode unit 33-20' in the fourth row group of the electrode sheet 13' and the conduction of the signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-16' to the electrode unit 33-20' in the fourth row group. The bidirectional switches 55' are switched between and cooperate with the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', fourth control switch 54-4', and fifth control switch 54-5' to enable the fourth row of electrode units 33-16' to electrode units 33-20' to transmit separate alternating electrical signals to the patient or enable the temperature detection signals detected by one or more combinations of the temperature detection units 35' corresponding to these electrode units 33' to be sampled and output to the corresponding ADC unit 52'. The above-mentioned bidirectional switches 55' can be mechanical switches, such as relays. The bidirectional switches 55' can also be electronic switches, and each bidirectional switch 55' can be switched by an additional first controller 51'.

[0436] In this embodiment, the multiple sets of bidirectional switches 55' are all electronic switches. The first controller 51' is in communication with the multiple sets of bidirectional switches 55' and is configured to control the switching of the multiple bidirectional switches 55' in each set of bidirectional switches 55' between their respective terminals 1 and 2, and to coordinate the closing or opening of the corresponding control switch 54' to continuously monitor the patient's body surface temperature detected by all temperature detection units 35' on the electrode sheet 13' or to transmit an alternating electrical signal to the patient.

[0437] In this embodiment, each group of ADC units 52' is electrically connected to one end of a plurality of bidirectional switching switches 55' in a corresponding group of bidirectional switching switches 55' through a multi-channel circuit line (not numbered) in the adapter 20', and is configured to receive a temperature detection signal transmitted by the multiplexed signal line 19' of the corresponding electrode sheet 13', and convert the temperature detection signal from an analog signal to a digital temperature signal. Each group of ADC units 52' includes a plurality of detection channels A, B, C, and D, and each detection channel A, B, C, and D is used to connect to a corresponding one of the multiplexed signal lines 19' through the corresponding bidirectional switching switch 55'. Figure 28 As shown, each ADC unit 52' includes a total of four detection channels A, B, C, and D, namely the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. The first detection channel A is connected to the first dual-purpose signal line 19-1' via one end of the first bidirectional switch 55-1', the second detection channel B is connected to the second dual-purpose signal line 19-2' via one end of the second bidirectional switch 55-2', the third detection channel C is connected to the third dual-purpose signal line 19-3' via one end of the third bidirectional switch 55-3', and the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4' via one end of the fourth bidirectional switch 55-4'. Each detection channel A, B, C, and D is used to receive the temperature detection signal collected by the temperature detection unit 35' corresponding to the electrode unit 33' to which the corresponding dual-purpose signal line 19' is connected. In addition, each detection channel A, B, C, D is connected to a first power module 58' for providing detection voltage to the detection channel A, B, C, D via a corresponding voltage divider resistor 53' in the adapter 20'. The first power module 58' provides DC power.

[0438] In this embodiment, the first communication unit 56' is configured to acquire digital temperature signals output by multiple sets of ADC units 52' and transmit the digital temperature signals to the electric field generator 30'. The electric field generator 30' is further configured to control and adjust the voltage of the alternating electrical signal provided to the multiple electrode units 33' of the electrode sheet 13' based on the received digital temperature signals. For example, when any of the multiple digital temperature signals received exceeds a preset threshold, it indicates that the temperature detected by the temperature detection unit 35' corresponding to at least one electrode unit 33' in the electrode sheet 13' exceeds a preset threshold temperature (e.g., 41°C, 42°C, etc.). At this time, the voltage of the alternating electrical signal output by the electric field generator 30' can be appropriately reduced or stopped to prevent the electrode units 33' of the electrode sheet 13' from overheating when the alternating electrical signal is applied, thereby preventing low-temperature burns on the patient's skin. The above-mentioned preset threshold temperature and preset threshold value can be determined based on human safety thresholds. The first communication unit 56' is controlled by the first controller 51' and serially transmits the digital temperature signals converted by the multiple sets of ADC units 52'. In this embodiment, the preset threshold temperature may be a value within the range of 36°C-45°C.

[0439] refer to Figure 28In this embodiment, the first power module 58' is electrically connected to the second power module 32' of the electric field generator 30' and is configured to supply power to the first controller 51', multiple ADC units 52', and the first communication unit 56' of the adapter 20'. A first connector 60' is connected between each electrode sheet 13' and the adapter 20'. The first connector 60' is suitable for connecting the corresponding electrode sheet 13' to the adapter 20'. A second connector 70' is provided between the adapter 20' and the electric field generator 30'. The second connector 70' is suitable for connecting the electric field generator 30' to the adapter 20'. The adapter 20' also includes a second cable 25' connected to the second connector 70'. The second connector 70' includes a second plug 71' provided at the end of the second cable 25' away from the first controller 51' and a second socket 72' provided on the electric field generator 30'. The second plug 71' and the second socket 72' are push-type spring connectors, meaning that the second connector 70' uses a connector to connect the adapter 20' to the electric field generator 30'. Each first connector 60' (e.g., X1, Y1, X2, and Y2) is connected to the second connector 70' via a corresponding four-way alternating power line 57'. The first connectors 60' (e.g., X1, Y1, X2, and Y2) are also connected to a corresponding set of control switches 54' and a corresponding set of ADC units 52'. Each first connector 60' is connected to the second connector 70' and a corresponding set of ADC units 52' via a corresponding set of bidirectional switches 55'. The second cable 25' has eight conductors, including four five-core conductors 1 through 4 electrically connected to the corresponding four alternating power lines 57' and used to transmit different alternating electrical signals; a conductor 5 electrically connected to the data receive line RX' of the first communication unit 56'; a conductor 6 electrically connected to the data transmit line TX' of the first communication unit 56'; a conductor 7 electrically connected to the VCC power line of the first power module 58'; and a conductor 8 electrically connected to the GND line of the first power module 58'. A second connector 70' is connected to the first communication unit 56' via the data receive line RX' and the data transmit line TX'. The VCC pin of the second connector 70' is connected to the VVC power line of the first power module 58', and the GND pin of the second connector 70' is connected to the GND line of the first power module 58' and is grounded. The VCC pin of the second connector 70' is also connected to the corresponding set of voltage dividers 53' and the corresponding set of ADC units 52' via the VCC power line of the first power module 58'.

[0440] refer to Figure 28 and Figure 31The electric field generator 30' includes a second power supply module 32', a second controller 37', an AC signal generator 39', a second communication unit 38', and multiple power switches 40'. The VCC pin of the second connector 70' is also electrically connected to the VCC power line of the second power supply module 32', and the GND pin of the second connector 70' is grounded via the GND line of the second power supply module 32'. The second power supply module 32' is also connected to the second controller 37' and the AC signal generator 39', respectively, and supplies power to them. The second communication unit 38' is electrically connected to the wire 5 of the second connector 70' via its data receiving line RX' and to the wire 6 of the second connector 70 via its data transmitting line TX', thereby enabling information exchange between the electric field generator 30' and the adapter 20'. The second controller 37' is also electrically connected to the second communication unit 38', the AC signal generator 39', and the multiple groups of power switches 40'. The second controller 37' is configured to control the opening and closing of each of the multiple groups of power switches 40' based on the relevant digital temperature signals received by the second communication unit 38' from the adapter 20', and to adjust the relevant parameters of the different alternating electrical signals applied by the AC signal generator 39. The AC signal generator 39 is electrically connected to the conductors 1 to 4 that transmit different alternating electrical signals to the second connector 70' through the multiple groups of power switches 40'. Each group of power switches 40' includes multiple power switches 40', and the multiple groups of power switches 40' are arranged in a one-to-one correspondence with the multiple electrode sheets 13'. Each group of power switches 40' is electrically connected to a corresponding four-core conductor 1, 2, 3, 4 for transmitting alternating electrical signals in the second connector 70' through a four-core AC power line 41-1', 41-2', 41-3', 41-4' and electrically connected to the corresponding electrode sheet 13' through the corresponding four-core conductors 1, 2, 3, 4 of the second connector 70', so as to transmit different alternating electrical signals to the electrode units 33' of each row group in each electrode sheet 13. The AC signal generator 39' is electrically connected to multiple groups of power switches 40' through a five-core AC power line 41'. Specifically, the number of groups of power switches 40' of the electric field generator 30' is related to the number of electrode sheets 13'. In this embodiment, the number of groups of power switches 40' is equal to the number of electrode sheets 13' and both are 4. The number of multiple power switches 40' in each group of power switches 40' is related to the number of row groups of corresponding electrode sheets 13'. In this embodiment,The number of power switches 40' in each group is equal to the number of rows of corresponding electrode sheets 13', which is four. The multiple groups of power switches 40' include a first group of power switches 40-1', a second group of power switches 40-2', a third group of power switches 40-3', and a fourth group of power switches 40-4', which are electrically connected to the four-core wires 1 to 4 of the second connector 70' in a one-to-one correspondence. One end of the first power switch 40-1' is electrically connected to the AC signal generator 39' through the four-core AC power line (not numbered) of the electric field generator 30', and the other end is electrically connected to the corresponding four-core wire 1 for transmitting alternating electric signals in the second connector 70' through a four-core AC power line 41-1', and is electrically connected to the four-way alternating power line 57' at the port X1' of the adapter 20' through the four-core wire 1 of the second connector 70', and the four-way alternating power line 57' at the port X1' of the adapter 20' is electrically connected to the first connector 60', and the first connector at the port X1 of the adapter 20' is electrically connected to the first connector 60'. The controller 60' is electrically connected to the corresponding electrode sheet 13' to control whether the AC signal generator 39' transmits different alternating electric signals to the electrode units 33' in the four row groups corresponding to the four-way alternating power lines 57' in the electrode sheet 13' electrically connected to the port X1 of the adapter 20'; one end of the second group of power switches 40-2' is electrically connected to the AC signal generator 39' through the four-core AC power line (unnumbered) of the electric field generator 30', and the other end is electrically connected to the corresponding four-core wire 2 for transmitting alternating electric signals in the second connector 70' through a four-core AC power line 41-2' and is connected to the second connector 70' through the second connector 70'. The four-core conductor 2 is electrically connected to the four-way alternating power line 57' at the port Y1' of the adapter 20', the four-way alternating power line 57' at the port Y1' of the adapter 20' is electrically connected to the first connector 60', and the first connector 60' at the port Y1' of the adapter 20' is electrically connected to the corresponding electrode sheet 13' to control whether the AC signal generator 39' transmits different alternating electrical signals to the electrode units 33' in the four row groups corresponding to the four-way alternating power line 57' in the electrode sheet 13' electrically connected to the port Y1' of the adapter 20'; one end of the third group of power switches 40-3' is connected to the first connector 60'. The four-core AC power cord (unnumbered) of the electric field generator 30' is electrically connected to the AC signal generator 39'. The other end is electrically connected to the corresponding four-core wire 3 for transmitting alternating electric signals in the second connector 70' through a four-core AC power cord 41-3'. The four-core wire 3 of the second connector 70' is electrically connected to the four-way AC power cord 57' at the port X2' of the adapter 20', the four-way AC power cord 57' at the port X2' of the adapter 20' is electrically connected to the first connector 60', and the first connector 60' at the port X2' of the adapter 20' is electrically connected to the corresponding electrode sheet 13'.To control whether the AC signal generator 39' transmits different alternating electric signals to the electrode units 33' in the four row groups corresponding to the four-way alternating power lines 57' in the electrode sheet 13' electrically connected to the port X2' of the adapter 20'; one end of the fourth group of power switches 40-4' is electrically connected to the AC signal generator 39' through the four-core AC power line (unnumbered) of the electric field generator 30', and the other end is electrically connected to the corresponding four-core wire 4 for transmitting alternating electric signals in the second connector 70' through a four-core AC power line 41-4' and is connected to the second connector 70' through the second connector 70 The four-core conductor 4 is electrically connected to the four-way alternating power line 57' at port Y2' of the adapter 20', the four-way alternating power line 57' at port Y2' of the adapter 20' is electrically connected to the first connector 60', and the first connector 60' at port Y2' of the adapter 20' is electrically connected to the corresponding electrode sheet 13' to control whether the AC signal generator 39' transmits different alternating electrical signals to the electrode units 33' in the four row groups corresponding to the four-way alternating power lines 57' in the electrode sheet 13' electrically connected to port Y1' of the adapter 20'.

[0441] The following will refer to Figures 28 to 31 The working principle of the tumor electric field treating system 100 ′ of this embodiment is described in detail.

[0442] It should be noted that the operating principle of temperature acquisition of the tumor treating field system 100 ′ is the same as that of the tumor treating field system 100 , and will not be described in detail here.

[0443] The working principle of applying the alternating electric signal of the tumor electric field therapy system 100' is similar to that of the tumor electric field therapy system 100, except that: this embodiment can apply different alternating electric signals to the electrode units 33' located in different row groups at the same time, which is more flexible.

[0444] Specifically, when it is necessary to apply an alternating electric signal to each electrode unit 33' of a certain electrode sheet 13', the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls the two ends of each of the multiple bidirectional switching switches 55' of a group of bidirectional switching switches 55' electrically connected to the electrode sheet 13' to be turned on and one end to be turned off, and at the same time controls all the control switches 54' in the corresponding group of control switches 54' to be turned off, and controls a group of power supply switches 40' electrically connected to the electrode sheet 13' to be turned on. At this time, the second controller 37' of the electric field generator 30' controls the AC signal generator 39' to apply different alternating electric signals to each row group of electrode units 33' of the electrode sheet 13' through different alternating power lines 57', and the voltage or current of the different applied alternating electric signals can be adjusted. That is, the switching unit (not numbered) is configured to switch the dual-purpose signal lines 19 corresponding to at least two row groups to connect to different alternating power lines 57 ′, so that different alternating electrical signals are applied to the electrode units 33 of each row group based on different alternating power lines 57 ′.

[0445] It should be noted that, in other embodiments, the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' can also be used to control a group of bidirectional switches 55' electrically connected to a certain electrode sheet 13' to apply different alternating electric signals to some electrode units 33' of the electrode sheet 13' in the same time period. For example, the first controller 51' of the adapter 20' or the second controller 37' of the electric field generator 30' controls the two ends of the first bidirectional switch 55-1' in the multiple bidirectional switches 55' of a group of bidirectional switches 55' electrically connected to the electrode sheet 13' to be turned on and one end to be turned off, and at the same time controls all the control switches 54' in the corresponding group of control switches 54' to be turned off, and controls a group of power switches 40' electrically connected to the electrode sheet 13' and a power switch 40' corresponding to the first bidirectional switch 55-1' to be turned on. At this time, the second controller 37' of the electric field generator 30' controls the AC signal generator 39' to apply an alternating electric signal to the first row group electrode unit 33-1' to the electrode unit 33-5' of the electrode sheet 13' through the corresponding alternating power line 57', and the voltage or current of the applied alternating electric signal is adjustable. It should be noted that, in other embodiments, different alternating electrical signals may be applied simultaneously to two or three rows of electrode units 33 ′ within the same time period, which will not be described in detail here.

[0446] It should be noted that in the embodiment of the present application, the control switch 54' electrically connected to each of the multiple grounding lines 18' of the electrode sheet 13' and the bidirectional switch 55' electrically connected to each of the multiple dual-purpose signal lines 19' of the electrode sheet 13' are both located in the adapter 20'. However, in other embodiments, the control switch 54' electrically connected to the grounding line 18' and the bidirectional switch 55' electrically connected to the dual-purpose signal line 19' can also be located on the electrode sheet 13' or in the electric field generator 30', which will not be described in detail here. In addition, the ADC unit 52' located in the adapter 20' can also be located in the electric field generator 30' and directly controlled by the second controller 37'.

[0447] The tumor electric field therapy system 100' of the present application can achieve real-time and comprehensive monitoring of the temperature of all electrode units 33' on the electrode sheet 13' without increasing the weight of the electrode sheet 13' or adding the core of the first cable 15' electrically connected to the electrode sheet 13', and then determine whether the electrode sheet 13' is qualified based on the obtained temperature detection signal; or determine whether the temperature detection unit 35' of the electrode sheet 13' is faulty or abnormal based on the obtained temperature detection signal, and determine whether the electrode sheet 13' needs to be replaced based on the number of faulty or abnormal temperature detection units 35' obtained; or identify the type of the electrode sheet based on the obtained temperature detection signal if the electrode sheet 13' is qualified; or determine whether the electrode unit 33' of the electrode sheet 13' is overheated based on the obtained temperature detection signal if the electrode sheet 13' is qualified, and then control the alternating electric signal applied to the electrode sheet 13' or the electrode units 33' of the corresponding row of the electrode sheet 13', so as to avoid low-temperature burns on the patient's body surface when tumor treatment is performed through the electrode sheet 13'. In addition, the substrate 31' of the electrode sheet 13' of the present application is electrically connected to the same electrode unit 33' and the signal end 35-2' of the corresponding temperature detection unit 35' through the same dual-purpose signal line 19'. While it can transmit both alternating electrical signals and direct current signals for temperature signal acquisition and the collected temperature detection signals through the dual-purpose signal line 19', it also greatly reduces the number of conductive traces (grounding line 18', dual-purpose signal line 19') laid thereon, reducing the wiring difficulty of the substrate 31', simplifying the manufacturing process, reducing the weight of the substrate 31', and reducing manufacturing costs. The electrode sheet 13' of the present application can also switch between applying alternating electrical signals for tumor treatment and transmitting direct current signals for temperature acquisition and transmitting the collected temperature detection signals through the combined control of a control switch 54' electrically connected to the grounding line 18' laid thereon and a bidirectional switching switch 55' electrically connected to the dual-purpose signal lin...

Claims

1. A tumor electric field treatment system, characterized in that: include: At least one pair of electrode sheets, each of which includes a plurality of electrode units and a plurality of temperature detection units, each of which can apply an alternating electrical signal, and each of which is provided corresponding to one electrode unit to detect the temperature at the corresponding electrode unit, wherein: The plurality of electrode units are configured into at least two row groups and at least two column groups; the ground terminals of the temperature detection units in the same column group are commonly connected to the ground pin via the same control switch, while the ground terminals of the temperature detection units in different column groups are respectively connected to the ground in parallel via different control switches; the temperature detection units in the same row group are connected in series, and the signal terminals of the temperature detection units are respectively short-circuited with the corresponding electrode units and then commonly connected to the switching unit via the same dual-purpose signal line; the signal terminals of the temperature detection units in different row groups are respectively short-circuited with the corresponding electrode units and then connected in parallel to the switching unit via different dual-purpose signal lines; The switching unit is configured to switch the dual-purpose signal line to the corresponding temperature sampling point or alternating power line of the switching unit so that When the dual-purpose signal line is connected to the temperature sampling point, the temperature detection signals of one or more combinations of all temperature detection units are sampled based on the temperature sampling point by configuring the switch states of the control switches to sequentially turn on the control switches. In a case where the dual-purpose signal line is connected to the alternating power line, the electrode units of at least one row group are applied with the alternating electrical signal based on the alternating power line.

2. The tumor electric field treatment system according to claim 1, characterized in that: The switching unit includes at least two bidirectional switches, the first end of each bidirectional switch serving as a temperature sampling point for the corresponding row group, the second end of each bidirectional switch simultaneously connected to the alternating power line, and the third end of each bidirectional switch connected to the dual-purpose signal line corresponding to each row group.

3. The tumor electric field treatment system according to claim 2, characterized in that: The switching unit is further configured to switch the dual-purpose signal line corresponding to each row group to be connected to the alternating power line, so that the electrode units of each row group are simultaneously applied with the alternating electrical signal based on the alternating power line.

4. The tumor electric field treatment system according to claim 2, characterized in that: The switching unit is further configured to switch the dual-purpose signal lines corresponding to at least two of the row groups to be connected to the alternating power line at the same time, so that the electrode units of at least two of the row groups are simultaneously applied with the alternating electrical signal based on the alternating power line.

5. The tumor electric field treatment system according to claim 2, characterized in that: The intensity of the alternating electric signal output by the alternating power line is adjustable.

6. The tumor electric field treatment system according to claim 1, characterized in that: The switching unit includes at least two bidirectional switches, the first end of each bidirectional switch serving as a temperature sampling point for the corresponding row group, the second end of each bidirectional switch connected to a different alternating power line, and the third end of each bidirectional switch connected to a dual-purpose signal line corresponding to each row group.

7. The tumor electric field treatment system according to claim 6, characterized in that: The switching unit is further configured to switch the dual-purpose signal lines corresponding to the at least two row groups to connect to different alternating power lines, so that the alternating electrical signals are applied to the electrode units of each row group based on different alternating power lines.

8. The tumor electric field treatment system according to claim 6, characterized in that: The intensity of the alternating electric signals output by different alternating power lines can be adjusted respectively.

9. The tumor electric field treatment system according to claim 1, characterized in that: It also includes multiple diodes, each of which is arranged corresponding to a temperature detection unit, wherein the anode of each diode is connected to the ground end of the corresponding temperature detection unit, and the cathodes of the diodes corresponding to each column group are connected together and then connected to the ground pin through the corresponding control switch.

10. The tumor electric field treatment system according to claim 1, characterized in that: Each of the temperature sampling points is connected to a DC power supply via a corresponding voltage dividing resistor.

11. The tumor electric field treatment system according to claim 10, characterized in that: An adapter is also included, wherein the control switch, the switching unit and the voltage dividing resistor are respectively arranged in the adapter.

12. The tumor electric field treatment system according to claim 11, characterized in that: The adapter includes a first controller and an ADC unit, the ADC unit is connected to each of the temperature sampling points to sample the temperature detection signal through each of the temperature sampling points, and the first controller is connected to the ADC unit to determine the temperature at the corresponding electrode unit based on the digital temperature signal output by the ADC unit.

13. The tumor electric field treatment system according to claim 12, characterized in that: The first controller is further configured to configure a switching state of the control switch.

14. The tumor electric field treatment system according to claim 12, wherein: The first controller is further configured to configure a switching state of the bidirectional switch in the switching unit.

15. The tumor electric field treatment system according to claim 1, wherein: The device further includes an electric field generator configured to output the alternating electric signal through the alternating power line.

16. The tumor electric field treatment system according to claim 15, characterized in that: The electric field generator includes a second controller and an AC signal generator. The second controller is connected to the AC signal generator. The second controller is configured to control the AC signal generator to adjust the intensity of the alternating electric signal output by the alternating power line.

17. The tumor electric field treatment system according to claim 16, wherein: The electric field generator is further configured to obtain the temperature of each electrode unit and control the AC signal generator according to the temperature of each electrode unit.

18. The tumor electric field treatment system according to claim 16, wherein: The electric field generator further includes a power switch, which is disposed between the AC signal generator and the switching unit. Under the configuration of the second controller, the power switch controls whether the AC signal generator outputs the alternating electric signal through the alternating power line.

19. The tumor electric field treatment system according to claim 16, wherein: The second controller is further configured to configure the switching state of the control switch.

20. The tumor electric field treatment system according to claim 16, wherein: The second controller is further configured to configure a switching state of the bidirectional switch in the switching unit.

21. An electrode sheet, characterized in that: Applicable to a tumor electric field therapy system, the tumor electric field therapy system includes a switching unit, and the electrode sheet includes: substrate; A plurality of electrode units and a plurality of temperature detection units are provided on the substrate, each of the electrode units can apply an alternating electrical signal, and each of the temperature detection units is provided corresponding to one electrode unit to detect the temperature at the corresponding electrode unit, wherein, The plurality of electrode units are configured into at least two row groups and at least two column groups; The grounding terminals of the temperature detection units in the same column group are connected to the ground pin through the same control switch, and the grounding terminals of the temperature detection units in different column groups are connected to the ground in parallel through different control switches; The temperature detection units located in the same row group are connected in series, and the signal ends of the temperature detection units are respectively short-circuited with the corresponding electrode units and then connected to the switching unit through the same dual-purpose signal line. The signal ends of the temperature detection units located in different row groups are respectively short-circuited with the corresponding electrode units and then connected to the switching unit in parallel through different dual-purpose signal lines, so that the dual-purpose signal lines are switched by the switching unit to be connected to the corresponding temperature sampling points or alternating power lines of the switching units. When the dual-purpose signal line is connected to the temperature sampling point, the temperature detection signals of one or more combinations of all temperature detection units are sampled based on the temperature sampling point by configuring the switch states of the control switches to sequentially turn on the control switches. In a case where the dual-purpose signal line is connected to the alternating power line, the electrode units of at least one row group are applied with the alternating electrical signal based on the alternating power line.

22. The electrode sheet according to claim 21, characterized in that In a case where the dual-purpose signal lines corresponding to each row group are respectively connected to the alternating power line, the electrode units of each row group are simultaneously applied with the alternating electrical signal based on the alternating power line.

23. The electrode sheet according to claim 21, characterized in that In a case where the dual-purpose signal lines corresponding to at least two of the row groups are simultaneously connected to the alternating power line, the electrode units of at least two of the row groups are simultaneously applied with the alternating electrical signals based on the alternating power line.

24. The electrode sheet according to claim 21, characterized in that The intensity of the alternating electric signal output by the alternating power line is adjustable.

25. The electrode sheet according to claim 21, characterized in that In a case where the dual-purpose signal lines corresponding to the at least two row groups are connected to different alternating power lines, the alternating electrical signals are applied to the electrode units of each row group based on different alternating power lines.

26. The electrode sheet according to claim 25, characterized in that The intensity of the alternating electric signals output by different alternating power lines can be adjusted respectively.

27. The electrode sheet according to claim 21, characterized in that It also includes multiple diodes, each of which is arranged corresponding to a temperature detection unit, wherein the anode of each diode is connected to the ground end of the corresponding temperature detection unit, and the cathodes of the diodes corresponding to each column group are connected together and then connected to the ground pin through the corresponding control switch.

28. The electrode sheet according to claim 21, characterized in that Each of the temperature sampling points is connected to a DC power supply via a corresponding voltage dividing resistor.

29. The electrode sheet according to any one of claims 21 to 28, characterized in that: Each electrode unit is provided with a through hole, and the through hole is suitable for accommodating the temperature detection unit.

30. The electrode sheet according to any one of claims 21 to 28, characterized in that: The plurality of electrode units and the plurality of temperature detection units are arranged in an array in terms of spatial arrangement, and are arranged in a plurality of rows and columns in terms of circuit connection.

31. The electrode sheet according to claim 30, characterized in that There are 20 electrode units and 20 temperature detection units, and they are arranged in four rows and five columns in terms of circuit connection.

32. A tumor electric field treatment system, characterized in that: include: At least one pair of electrode sheets according to any one of claims 21 to 31; an electric field generator, the electric field generator being configured to generate an alternating electric signal and transmit the alternating electric signal to each of the electrode sheets via the alternating power line; A control unit is configured to configure at least one of the switching state of the control switch and the switching state of the switching unit so as to sample the temperature detection signals of one or more combinations of all the temperature detection units based on corresponding temperature sampling points, or to control at least one electrode unit of the row group to be applied with the alternating electrical signal based on the alternating power line.

33. A tumor treatment device, characterized in that: include: The tumor therapeutic field system according to any one of claims 1-20, or the tumor therapeutic field system according to claim 32.

34. A method for detecting electrode temperature, characterized in that: Applied to the tumor treating field system according to any one of claims 1-20 or the tumor treating field system according to claim 32, the method comprising: Controlling the switching unit so that the dual-purpose signal lines corresponding to each row group in the corresponding electrode sheet are sequentially connected to the corresponding temperature sampling points; The control switch corresponding to each column group is controlled so as to sample the temperature detection signal of the corresponding electrode unit based on the corresponding temperature sampling point.

35. A method for detecting abnormality of an electrode sheet, characterized in that: The adapter or the electric field generator is preset with a preset threshold and a preset temperature threshold, and the method includes: Determine the temperature detection signal of each electrode unit in each electrode sheet by executing the electrode sheet temperature detection method according to claim 34; It is determined whether the electrode sheet is abnormal according to the temperature detection signal.

36. The method according to claim 35, characterized in that Determining whether the electrode sheet is abnormal according to the temperature detection signal includes: When it is determined according to the temperature detection signal that any one electrode unit in the corresponding electrode sheet is abnormal or faulty, the electrode sheet is determined to be unqualified.

37. The method according to claim 35, wherein Determining whether the electrode sheet is abnormal according to the temperature detection signal includes: In the case where it is determined according to the temperature detection signal that an abnormal or faulty electrode unit exists in the corresponding electrode sheet, determining the number of the abnormal or faulty electrode units; When the number of abnormal or faulty electrode units reaches a preset threshold, it is determined that the electrode sheet needs to be replaced.

38. The method according to claim 35, characterized in that Determining whether the electrode sheet is abnormal according to the temperature detection signal includes: comparing the temperature of each electrode unit in the corresponding electrode sheet with a preset temperature threshold according to the temperature detection signal; Whether the temperature of the electrode sheet is abnormal is determined based on the comparison result.

39. The method according to claim 38, characterized in that Determine whether the temperature of the electrode sheet is abnormal based on the comparison result, including: When the temperature of any one electrode unit in the corresponding electrode sheet exceeds a preset temperature threshold, it is determined that the temperature of the electrode sheet is abnormal.

40. A tumor electric field treatment system, characterized in that: The device comprises an electrode sheet according to any one of claims 21 to 31 and an adapter or an electric field generator electrically connected to the electrode sheet, wherein a preset temperature threshold, a preset quantity threshold, a first preset temperature, and a second preset temperature are preset in the adapter or the electric field generator, and the adapter or the electric field generator is configured as follows: Determine the temperature detection signal of each electrode unit in each electrode sheet by executing the electrode sheet temperature detection method according to claim 34; The intensity of the alternating electric signal applied to the electrode unit is controlled according to the temperature detection signal.

41. The tumor electric field treatment system according to claim 40, wherein: The adapter or the electric field generator is configured as: comparing the temperature of each electrode unit in the electrode sheet with a preset temperature threshold according to the temperature detection signal; The intensity of the alternating electric signal is controlled according to the comparison result.

42. The tumor electric field treatment system according to claim 41, wherein: The adapter or the electric field generator is configured as: When the temperature of at least one electrode unit exceeds a preset temperature threshold, application of the alternating electrical signal to the electrode units of the electrode sheet is stopped.

43. The tumor electric field treatment system according to claim 42, wherein: The adapter or the electric field generator is configured as: Stop applying the alternating electrical signal to all electrode units of the electrode sheet; or Stop applying the alternating electric signal to all electrode units in the row group where the electrode unit exceeding the preset temperature threshold in the electrode sheet is located.

44. The tumor treatment field system according to claim 41, wherein: The adapter or the electric field generator is configured as: determining the number of over-temperature row groups if the temperature at at least one electrode unit exceeds a preset temperature threshold; When the number of the over-temperature row groups exceeds a preset number threshold, stopping applying the alternating electrical signal to all electrode units of the electrode sheet; or When the number of the over-temperature row groups does not exceed the preset number threshold, the application of the alternating electric signal to all electrode units in the row group where the electrode units exceeding the preset temperature threshold are located in the electrode sheet is stopped.

45. The tumor treatment field system according to claim 43 or 44, wherein: In the case of stopping applying the alternating electric signal to all electrode units in the row group where the electrode unit exceeding the preset temperature threshold in the electrode sheet is located, the adapter or the electric field generator is further configured to: The alternating electric signal is continuously applied to the electrode units in other row groups in the electrode sheet.

46. ​​The tumor electric field treatment system according to claim 45, wherein: The intensity of the alternating electric signal applied to the electrode units in other row groups in the electrode sheet is adjustable.

47. The tumor electric field treatment system according to claim 45, characterized in that The intensity of the alternating electric signal applied to the electrode units of each row group in the other row groups is adjustable.

48. The tumor treatment field system according to claim 41, wherein: The adapter or the electric field generator is configured as: When the temperatures at all electrode units in the electrode sheet do not exceed a preset temperature threshold, and when the temperatures at all electrode units in the electrode sheet do not exceed a first preset temperature, the intensity of the alternating electric signal applied to the electrode units of the electrode sheet is increased, wherein the first preset temperature is less than the preset temperature threshold.

49. The tumor electric field treatment system according to claim 48, wherein: When the temperature of all electrode units in the electrode sheet does not exceed a preset temperature threshold, the adapter or the electric field generator is further configured to: When the temperature of at least one electrode unit in the electrode sheet exceeds a first preset temperature and is less than a preset temperature threshold, the intensity of the alternating electric signal currently applied to the electrode unit of the electrode sheet is kept unchanged.

50. The tumor electric field treatment system according to claim 49, wherein: When the temperature of all electrode units in the electrode sheet does not exceed a preset temperature threshold, the adapter or the electric field generator is further configured to: When the temperature of at least one electrode unit in the electrode sheet exceeds a second preset temperature and is less than a preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit of the electrode sheet is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

51. The tumor treatment field system according to claim 44, wherein: When the number of the over-temperature row groups does not exceed a preset number threshold, the adapter or the electric field generator is further configured to: When the temperature of each electrode unit in the non-overtemperature row group does not exceed a first preset temperature, the intensity of the alternating electric signal applied to the electrode unit of the non-overtemperature row group is increased, wherein the first preset temperature is less than the preset temperature threshold.

52. The tumor electric field treatment system according to claim 51, wherein: When the number of the over-temperature row groups does not exceed a preset number threshold, the adapter or the electric field generator is further configured to: When the temperature of at least one electrode unit in the non-overtemperature row group exceeds the first preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal currently applied to the electrode unit of the non-overtemperature row group is kept unchanged.

53. The tumor electric field treatment system according to claim 52, wherein: When the number of the over-temperature row groups does not exceed a preset number threshold, the adapter or the electric field generator is further configured to: When the temperature of at least one electrode unit in the non-over-temperature row group exceeds a second preset temperature and is less than a preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit of the non-over-temperature row group is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

54. The tumor treatment field system according to claim 48 or 51, wherein: The electric field strengths corresponding to the row groups whose alternating electric signal strengths are increased have the same increase amplitude.

55. The tumor treatment field system according to claim 48 or 51, wherein: The increasing extents of the electric field intensities corresponding to the row groups where the alternating electric signal intensities are increased are different from each other.

56. The tumor treatment field system according to claim 49 or 52, wherein: The adapter or the electric field generator is configured as: The intensity of the alternating electric signal currently applied to the first target row group is kept unchanged, wherein the first target row group is a row group where the temperature of the electrode unit exceeds a first preset temperature and is less than a preset temperature threshold.

57. The tumor treatment field system according to claim 50 or 53, wherein: The adapter or the electric field generator is configured as: The intensity of the alternating electric signal applied to the electrode units of the second target row group is reduced, wherein the second target row group is a row group where the temperature of the electrode units exceeds a second preset temperature and is less than a preset temperature threshold.

58. A method for identifying electrode type, characterized in that: The method comprises: Determine the temperature detection signal of each electrode unit in each electrode sheet by executing the electrode sheet temperature detection method according to claim 34; The type of the electrode sheet is identified according to the temperature detection signal.

59. A computer-readable storage medium, characterized in that A computer program is stored thereon, which, when executed by a processor, implements The electrode temperature detection method according to claim 34; or The electrode sheet abnormality detection method according to any one of claims 35 to 39; or The electrode sheet type identification method according to claim 58.

60. A tumor electric field therapy adapter, comprising a first memory and a first controller, characterized in that: The first memory stores a computer program, which, when executed by the first controller, implements The electrode temperature detection method according to claim 34; or The electrode sheet abnormality detection method according to any one of claims 35 to 39; or The electrode sheet type identification method according to claim 58.

61. An electric field generator for tumor electric field therapy, comprising a second memory and a second controller, characterized in that: The second memory stores a computer program, which, when executed by the second controller, implements The electrode temperature detection method according to claim 34; or The electrode sheet abnormality detection method according to any one of claims 35 to 39; or The electrode sheet type identification method according to claim 58.

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