Brain blood oxygen collection layout method and device with high spatial resolution and storage medium
The multi-layer symmetrical and modular arrangement of light sources and detectors in near-infrared brain imaging systems addresses spatial resolution and efficiency issues by optimizing detector placement and channel density, enhancing data acquisition efficiency, and reducing system complexity, while ensuring accurate and real-time monitoring of brain blood oxygen levels.
Patent Information
- Application Number
- CN202411448459.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-17
- Publication Date
- 2024-12-20
AI Technical Summary
Traditional near-infrared brain imaging systems face challenges in improving spatial resolution while reducing complexity and cost, minimizing signal interference, and ensuring efficient data acquisition due to fixed light source and detector arrangements.
A high spatial resolution cerebral blood oxygen collection layout method involving a multi-layer symmetrical arrangement of light sources and detectors, with each light source forming optical path channels with multiple detectors at specific distances and angles, and a modular design to increase channel density and reuse detectors.
The method enhances spatial resolution, reduces system complexity, and improves data acquisition efficiency by increasing the number of optical path channels without increasing the number of light sources, ensuring accurate and real-time monitoring of brain blood oxygen levels.
Smart Images
Figure CN119157534A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of brain function imaging, and in particular to a high spatial resolution brain blood oxygen collection layout method, device and storage medium. Background Art
[0002] With the rapid development of biomedical engineering, near-infrared brain functional imaging technology has become one of the important tools in brain function research and clinical diagnosis. Near-infrared brain functional imaging technology can monitor the metabolism and blood flow activity of the brain in real time by detecting changes in blood oxygen levels in the cerebral cortex. This technology relies on the near-infrared light emitted by the light source to penetrate the hair, scalp and skull, then be scattered by the vascular tissue of the cerebral cortex, and finally be received by the detector. By detecting changes in oxygenated hemoglobin, deoxygenated hemoglobin and total blood oxygen concentration, researchers can obtain local brain hemodynamic information, which is of great significance for the study of brain function and the early diagnosis and monitoring of neurological diseases.
[0003] Traditional near-infrared brain imaging systems usually use a fixed number of light sources and detectors, and construct multiple light source-detector channels by arranging them at specific locations on the scalp surface. These channels are used to collect brain blood oxygen information in different areas. In order to improve spatial resolution, more channels are usually constructed by increasing the number of light sources and detectors. However, this approach faces multiple technical challenges. First, increasing the number of light sources and detectors will increase the complexity and cost of the system. Second, the layout of light sources and detectors and the minimum spacing between channels have a direct impact on the acquisition accuracy and channel density of the system. If the spacing is too large, the spatial resolution is low; if the spacing is too small, signal interference between channels may occur, affecting the accuracy of the data. In addition, an excessive number of light sources may cause the system feedback time to be prolonged, reducing the efficiency of real-time acquisition.
[0004] Therefore, current technology urgently needs a new layout method to optimize the layout of detectors and light sources while reducing the number of light sources, improve the spatial resolution of blood oxygen collection, reduce the complexity of the system, and at the same time ensure the sampling frequency of the system and the accuracy of data acquisition. Summary of the invention
[0005] This application provides a high spatial resolution brain blood oxygen collection layout method, device and storage medium, which can optimize the layout of detectors and light sources while reducing the number of light sources, and improve the spatial resolution of blood oxygen collection. This application provides the following technical solutions:
[0006] In a first aspect, the present application provides a high spatial resolution cerebral blood oxygen collection layout method, the method comprising:
[0007] In the collection area, multiple light sources and detectors are arranged;
[0008] The light sources and detectors are arranged in a multi-layer symmetrical structure, each layer contains a number of light sources and detectors, and the light sources and detectors are arranged at a predetermined geometric distance;
[0009] Each light source forms an optical path channel with at least four detectors, and the detectors are arranged around the light source at different radii, wherein the distance between the light source and the detector ranges from 0.75 cm to 4.24 cm;
[0010] Multiple optical path channels are formed between multiple light sources and detectors. The minimum spacing between the channels is 0.75 cm, and the spacing between different channels is adjusted according to the relative position of the detector and the light source.
[0011] In a specific implementation scheme, the light sources are arranged in a polygonal or radial shape, and the arrangement between each light source and the detector follows the following principles:
[0012] Each light source is located at a central position, and a plurality of detectors are symmetrically distributed in a ring or polygon around the light source;
[0013] Additional collection channels are generated between adjacent light sources and detectors through different arrangements, ensuring that at least one optical path channel is formed between each light source and multiple detectors.
[0014] In a specific possible implementation scheme, each acquisition module includes 5 light sources and at least 20 detectors, each light source forms an optical path channel through a plurality of different detectors, and the channels between adjacent light sources are arranged compactly.
[0015] In a specific implementation scheme, the light source and the detector are arranged as follows:
[0016] Each light source and its adjacent detector form at least four light path channels, and the channels are evenly distributed in the collection area;
[0017] By adjusting the relative position of the light source and the detector, the density of the collection channel is increased to ensure that the minimum spacing of the optical path channel is 0.75 cm.
[0018] In a specific implementation scheme, the ratio of the number of detectors to light sources is 1.5:1 to 2:1, the number of light sources is less than the number of detectors, and the arrangement of light sources and detectors forms multiple collection areas through modular design.
[0019] In a specific possible implementation scheme, the light source and the detector are arranged in a modular design, each module includes at least two light sources and multiple detectors, and the light sources and detectors of adjacent modules are staggered to form a cross-module collection channel.
[0020] In a specific possible implementation scheme, the distance between the light source and the detector is arranged at non-uniform intervals, and the arrangement spacing of the detectors varies in different areas, and the detector spacing close to the target area is smaller than the detector spacing far from the target area.
[0021] In a specific possible implementation manner, the light sources and detectors are arranged in such a manner that different optical path channels are formed between each light source and a plurality of detectors around it, and each detector receives signals from different light sources at the same time.
[0022] In a second aspect, the present application provides an electronic device, comprising a processor and a memory; the memory stores a program, and the program is loaded and executed by the processor to implement a high spatial resolution cerebral blood oxygen collection layout method as described in the first aspect.
[0023] In a third aspect, the present application provides a computer-readable storage medium, wherein the storage medium stores a program, and when the program is executed by a processor, it is used to implement a high spatial resolution cerebral blood oxygen acquisition layout method as described in the first aspect.
[0024] In summary, the beneficial effects of this application include at least:
[0025] 1) By optimizing the arrangement of light sources and detectors, the number of effective optical path channels is increased, thereby improving the spatial resolution of the acquisition system and being able to more accurately reflect local blood oxygen changes in the brain.
[0026] 2) Through the reuse of detectors and the design of cross-module channels, the efficiency of signal acquisition is improved, the sampling cycle of the system is reduced, and faster feedback and real-time monitoring are achieved.
[0027] By optimizing the arrangement of light sources and detectors, a high-density arrangement of optical path channels is achieved. Specifically, the present invention adopts a modular layout design, and multiple light sources and detectors are arranged at reasonable angles and spacings, so that each light source can be paired with multiple detectors to form multiple optical path channels, and the number of channels is further increased by reusing detectors and designing cross-module optical paths. While reducing the number of light sources, this method improves the spatial resolution and signal density of the acquisition system, thereby effectively solving the problems of insufficient optical path channels and low acquisition accuracy in the prior art.
[0028] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application and implement it according to the contents of the specification, the following is a detailed description of the preferred embodiments of the present application in conjunction with the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS
[0029] Figure 1This is a schematic diagram of a use case of a high spatial resolution brain blood oxygen collection layout method in an embodiment of the present application. Figure 1 .
[0030] Figure 2 This is a schematic diagram of a use case of a high spatial resolution brain blood oxygen collection layout method in an embodiment of the present application. Figure 2 .
[0031] Figure 3 This is a schematic diagram of a use case of a high spatial resolution brain blood oxygen collection layout method in an embodiment of the present application. Figure 3 .
[0032] Figure 4 It is a block diagram of an electronic device with a high spatial resolution cerebral blood oxygen collection layout in an embodiment of the present application. DETAILED DESCRIPTION
[0033] The specific implementation methods of the present application are further described in detail below in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present application but are not intended to limit the scope of the present application.
[0034] Optionally, the present application uses the high spatial resolution cerebral blood oxygen collection layout method provided in each embodiment as an example for explanation in an electronic device, where the electronic device is a terminal or a server. The terminal may be a mobile phone, a computer, a tablet computer, etc. This embodiment does not limit the type of electronic device.
[0035] Reference Figure 1 , is a use case diagram of a high spatial resolution cerebral blood oxygen collection layout method provided by an embodiment of the present application. As can be seen from the figure, the basic structure of the high spatial resolution cerebral blood oxygen collection layout method includes multiple light sources and detectors, and these light sources and detectors are arranged according to certain rules to form multiple optical path channels.
[0036] It should be noted that Figure 1 , Figure 2 , Figure 3 In the layout design, different colors represent different distances between light sources and detectors, so as to clearly indicate the arrangement relationship between each channel. Black line (2.12cm): represents the channel with the minimum distance between the light source and the detector. This distance is used to achieve higher spatial resolution. Blue line (3cm): represents the medium distance channel. This distance helps to increase the number of channels and provide support for detecting a larger range of blood oxygen changes in the brain. Green line (3.35cm): represents a channel with a slightly larger distance, which is used to cover a wider range of detection areas and further improve the detection accuracy of the system. Red line (4.24cm): It is a new light source-detector channel formed across modules in the layout, forming a longer distance collection channel, which helps to improve sampling efficiency.
[0037] Specifically, each group of acquisition units includes several light sources and detectors. The light sources and detectors are arranged in a certain rule, and each light source can form an optical path channel with multiple detectors around it. In the illustrated layout, the first layout unit consisting of 5 light sources and 20 detectors is used. Each light source and the detectors around it are arranged at a specific angle and spacing, so that each light source can be paired with at least four detectors to form an optical path channel. The minimum channel spacing is 0.75 cm. This design ensures that the optical path channels between the light source and the detector will not overlap or interfere at the minimum distance through a compact arrangement.
[0038] In addition, the arrangement of light sources and detectors is based on a modular design, and each module contains multiple light sources and detectors. Adjacent modules arrange light sources and detectors in a staggered manner to ensure that the light paths between modules are independent and dense. For example, refer to Figure 2 In the 10 light sources + 40 detectors arrangement shown in the figure, multiple light sources and detectors are used, and each light source forms multiple light path channels around it. Through modular expansion, the number of light path channels can be further increased to 90 channels, and the minimum channel spacing is still maintained at 0.75 cm.
[0039] In practice, the distance between the light source and the detector varies according to different regional requirements. When close to the target area, the arrangement spacing of the detectors is small, forming a higher density of optical path channels; when far away from the target area, the arrangement spacing of the detectors is appropriately increased. The distance between different light sources and detectors can be accurately calculated and designed to ensure that signal interference and overlap are avoided when the optical path channels are dense.
[0040] In some designs, some detectors can be used for signal reception from multiple light sources, e.g. Figure 3 In the layout of 10 light sources + 35 detectors shown in the figure, 5 detectors are reused by multiple light sources to form 84 optical path channels. The design of detector sharing can further reduce the number of detectors without reducing the total number of optical path channels. The light sources and detectors of adjacent modules are arranged in a staggered manner to form cross-module optical path channels. This can significantly increase the number of optical path channels in the overall layout and improve the spatial resolution. Each light source can form optical path channels of different lengths and angles by pairing with multiple detectors. These channels exist and run in parallel at the same time, thereby increasing the diversity of signal acquisition.
[0041] In summary, there are three embodiments in this application as follows:
[0042] like Figure 1 The first is a 5-light source + 20-detector layout. In this layout, 5 light sources are paired with 20 detectors to form 40 light path channels, and the minimum channel spacing is 0.75 cm.
[0043] Specifically, there are 5 light sources in the layout, which are located in the central area of the entire layout and are distributed in a cross shape. Each light source is connected to multiple detectors around it to form several channels. The red dots in the figure indicate the positions of the light sources, which are located at the central and surrounding key points of the diagram, ensuring the uniform distribution of the light path. There are a total of 20 detectors, evenly distributed in the peripheral area around the light source, forming a radial layout. The number and distribution of detectors ensure that each light source can be connected to the detector through different paths to form multiple collection channels. A total of 40 channels are formed in the layout. Each channel consists of a light source and a detector paired together. The light emitted by the light source is scattered by the scalp, skull and cerebral cortex, and then received by the detector to complete the collection of blood oxygen information.
[0044] In the implementation, 5 light sources and 20 detectors form a 5×5 square array with a side length of 6 cm, in which 5 light sources occupy the 5 central positions and the remaining positions are occupied by detectors.
[0045] like Figure 2 The second is a 10 light source + 40 detector layout, which uses a layout design of 10 light sources and 40 detectors. In this case, 90 light path channels are formed, and the minimum channel spacing is 0.75 cm. This design significantly increases the number of light path channels by increasing the number of light sources and detectors.
[0046] In implementation, the first arrangement is bilaterally symmetrical to form the second layout.
[0047] like Figure 3 The third is a 10-light source + 35-detector layout. In this layout, 10 light sources are paired with 35 detectors, of which 5 detectors are reused by multiple light sources, forming 84 optical path channels with a minimum channel spacing of 0.75 cm.
[0048] In summary, by optimizing the arrangement of light sources and detectors, a high-density arrangement of optical path channels is achieved. Specifically, the present invention adopts a modular layout design, and multiple light sources and detectors are arranged at reasonable angles and spacings, so that each light source can be paired with multiple detectors to form multiple optical path channels, and the number of channels is further increased by reusing detectors and designing cross-module optical paths. While reducing the number of light sources, this method improves the spatial resolution and signal density of the acquisition system, thereby effectively solving the problems of insufficient optical path channels and low acquisition accuracy in the prior art.
[0049] Figure 4 4 is a block diagram of an electronic device provided by an embodiment of the present application. The device at least includes a processor 401 and a memory 402.
[0050] The processor 401 may include one or more processing cores, such as a 4-core processor, an 8-core processor, etc. The processor 401 may be implemented in at least one hardware form of DSP (Digital Signal Processing), FPGA (Field-Programmable Gate Array), and PLA (Programmable Logic Array). The processor 401 may also include a main processor and a coprocessor. The main processor is a processor for processing data in the awake state, also known as a CPU (Central Processing Unit); the coprocessor is a low-power processor for processing data in the standby state. In some embodiments, the processor 401 may be integrated with a GPU (Graphics Processing Unit), which is responsible for rendering and drawing the content to be displayed on the display screen. In some embodiments, the processor 401 may also include an AI (Artificial Intelligence) processor, which is used to process computing operations related to machine learning.
[0051] The memory 402 may include one or more computer-readable storage media, which may be non-transitory. The memory 402 may also include a high-speed random access memory, and a non-volatile memory, such as one or more disk storage devices, flash memory storage devices. In some embodiments, the non-transitory computer-readable storage medium in the memory 402 is used to store at least one instruction, which is used to be executed by the processor 401 to implement the high spatial resolution cerebral blood oxygen collection layout method provided in the method embodiment of the present application.
[0052] In some embodiments, the electronic device may further optionally include: a peripheral device interface and at least one peripheral device. The processor 401, the memory 402 and the peripheral device interface may be connected via a bus or a signal line. Each peripheral device may be connected to the peripheral device interface via a bus, a signal line or a circuit board. Schematically, the peripheral devices include but are not limited to: a radio frequency circuit, a touch display screen, an audio circuit, and a power supply.
[0053] Of course, the electronic device may also include fewer or more components, which is not limited in this embodiment.
[0054] Optionally, the present application also provides a computer-readable storage medium, in which a program is stored, and the program is loaded and executed by a processor to implement the high spatial resolution cerebral blood oxygen collection layout method of the above method embodiment.
[0055] Optionally, the present application also provides a computer product, which includes a computer-readable storage medium, in which a program is stored, and the program is loaded and executed by a processor to implement the high spatial resolution cerebral blood oxygen collection layout method of the above method embodiment.
[0056] The technical features of the above embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0057] The above embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application shall be subject to the attached claims.
Claims
1. A high spatial resolution brain blood oxygen collection layout method, characterized in that: The method comprises: In the collection area, multiple light sources and detectors are arranged; The light sources and detectors are arranged in a multi-layer symmetrical structure, each layer contains a number of light sources and detectors, and the light sources and detectors are arranged at a predetermined geometric distance; Each light source forms an optical path channel with at least four detectors, and the detectors are arranged around the light source at different radii, wherein the distance between the light source and the detector ranges from 0.75 cm to 4.24 cm; Multiple optical path channels are formed between multiple light sources and detectors. The minimum spacing between the channels is 0.75 cm, and the spacing between different channels is adjusted according to the relative position of the detector and the light source.
2. The high spatial resolution cerebral blood oxygen collection layout method according to claim 1, characterized in that: The light sources are arranged in a polygonal or radial shape, and the arrangement between each light source and the detector follows the following principles: Each light source is located at a central position, and a plurality of detectors are symmetrically distributed in a ring or polygon around the light source; Additional collection channels are generated between adjacent light sources and detectors through different arrangements, ensuring that at least one optical path channel is formed between each light source and multiple detectors.
3. The high spatial resolution cerebral blood oxygen collection layout method according to claim 2, characterized in that: Each acquisition module contains 5 light sources and at least 20 detectors. Each light source forms an optical path channel through multiple different detectors, and the channels between adjacent light sources are arranged compactly.
4. The high spatial resolution cerebral blood oxygen collection layout method according to claim 1, characterized in that: The arrangement of the light source and the detector is as follows: Each light source and its adjacent detector form at least four light path channels, and the channels are evenly distributed in the collection area; By adjusting the relative position of the light source and the detector, the density of the collection channel is increased to ensure that the minimum spacing of the optical path channel is 0.75 cm.
5. The high spatial resolution cerebral blood oxygen collection layout method according to claim 1, characterized in that: The ratio of the number of detectors to the number of light sources is 1.5:1 to 2:1, the number of light sources is less than the number of detectors, and the arrangement of the light sources and the detectors forms a plurality of collection areas through a modular design.
6. The high spatial resolution cerebral blood oxygen collection layout method according to claim 1, characterized in that: The arrangement of the light source and the detector adopts a modular design, each module includes at least two light sources and multiple detectors, and the light sources and detectors of adjacent modules are arranged in a staggered manner to form a cross-module collection channel.
7. The high spatial resolution cerebral blood oxygen collection layout method according to claim 1, characterized in that: The distance between the light source and the detector is arranged at non-uniform intervals, and the arrangement spacing of the detectors is different in different areas. The spacing of the detectors close to the target area is smaller than the spacing of the detectors far from the target area.
8. A high spatial resolution brain blood oxygen collection layout system, characterized in that: include: The light sources and detectors are arranged in such a way that different light paths are formed between each light source and a plurality of detectors around it, and each detector receives signals from different light sources at the same time.
9. An electronic device, characterized in that: The device includes a processor and a memory; a program is stored in the memory, and the program is loaded and executed by the processor to implement a high spatial resolution cerebral blood oxygen collection layout method as described in any one of claims 1 to 7.
10. A computer-readable storage medium, characterized in that: The storage medium stores a program, and when the program is executed by the processor, it is used to implement a high spatial resolution cerebral blood oxygen collection layout method as described in any one of claims 1 to 7.