Composition containing lucid ganoderma and application thereof

Abstract

The invention relates to the technical field of daily chemicals, in particular to a composition containing lucid ganoderma and application of the composition. The composition is prepared from honey, glycerol, p-hydroxyacetophenone, 1, 2-hexanediol, caprylyl glycol, an angelica sinensis extract and a ganoderma sinensis extract. The composition provided by the invention contains a plurality of plant components, so that the skin state with oil outside and dry inside can be synergistically improved in a multi-effect manner; the composition can balance the homeostasis, improve fine wrinkles, enhance skin elasticity and reproduce full skin, has the effects of tightening, resisting wrinkles, moisturizing and the like, and can improve wrinkles, improve pachulosis and make the skin tight and tender.

Description

Technical Field

[0001] The invention relates to the technical field of daily chemicals, and in particular to a composition containing ganoderma lucidum and application thereof. Background Art

[0002] Dong Quai is a traditional Chinese herbal medicine widely used in the field of TCM beauty. Dong Quai has the following benefits: Nourishing and replenishing: Dong Quai is rich in vitamins, minerals and other nutrients that are believed to nourish and replenish the skin, helping to improve skin tone and brighten the skin; Antioxidant effect: Dong Quai is rich in antioxidants, such as vitamin C and polyphenolic compounds, which can help reduce free radical damage to the skin and help slow the skin aging process; Circulation promotion: Traditionally, Dong Quai is believed to promote blood circulation, which may help improve the radiance and health of the skin; Soothing and anti-inflammatory: Dong Quai is widely believed to have soothing and anti-inflammatory effects, which can relieve problems such as skin sensitivity, redness, and inflammation.

[0003] Ganoderma lucidum is one of the famous higher medicinal fungi, known as "Lucky Grass" in ancient times and commonly known as "Immortal Grass". In the past 30 years, researchers have conducted extensive research on Ganoderma lucidum, and the results show that Ganoderma lucidum has a variety of pharmacological effects, such as enhancing immunity, inhibiting tumors, improving sleep, neuroprotection, anti-oxidation, prevention and treatment of cardiovascular diseases, anti-inflammation and liver protection.

[0004] To address this, the present invention provides a composition comprising Ganoderma lucidum and application thereof. Summary of the invention

[0005] In order to solve the above technical problems, the present invention provides a composition containing Ganoderma lucidum, wherein the composition comprises: honey, glycerin, p-hydroxyacetophenone, 1,2-hexanediol, caprylyl glycol, ANGELICASINENSIS extract, and GANODERMASINENSIS extract.

[0006] As an embodiment of the present invention, the composition further comprises: Angelica dahurica (ANGELICAPUBESCENS) root powder.

[0007] As an embodiment of the present invention, the composition further comprises: Component A: Ligusticum chuanxiong (LIGUSTICUM CHUANXIONG) root powder.

[0008] As an embodiment of the present invention, the composition further comprises: component B: ginseng (PANAX GINSENG) root powder, peony (PAEONIA LACTIFLORA) root powder, ampelopsis japonica extract, centella asiatica extract, astragalus membraneaceus extract, ginseng (PANAX GINSENG) root extract, honeysuckle (LONICERA JAPONICA) flower extract, peony (PAEONIA LACTIFLORA) extract.

[0009] As an embodiment of the present invention, the composition further comprises: Component C: Poria cocos (PORIA COCOS) extract.

[0010] As an embodiment of the present invention, the composition further comprises: Component D: Artemisia aargyi leaf extract, Atractylodes macrocephala extract, Camellia sinesis seed extract, Bletilla striata root extract.

[0011] As an embodiment of the present invention, the composition further comprises: Component E: Saussurea involucata extract, Iris ensata extract, and pearl powder.

[0012] The second aspect of the present invention provides a skin product containing Ganoderma lucidum, comprising the composition.

[0013] As an embodiment of the present invention, the composition is used in the field of skin care products.

[0014] As an embodiment of the present invention, the composition is used in the fields of moisturizing, nourishing, anti-wrinkle, and firming.

[0015] By adopting the above technical solution, the present invention has the following beneficial effects:

[0016] The composition provided by the present invention contains a variety of plant ingredients, which can synergistically improve the skin condition of oily skin on the outside and dry skin on the inside; balance homeostasis, improve fine lines, enhance skin elasticity, make the skin plump again, have the effects of firming, anti-wrinkle, moisturizing, etc., improve wrinkles, improve skin roughness, and make the skin firm and tender. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 : This is an image of wrinkles at the corners of the eyes. DETAILED DESCRIPTION

[0018] The technical solution of the present invention will be described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0019] The present invention provides a composition containing ganoderma lucidum. The composition contains, by weight, 8 parts of honey, 56 parts of glycerin, 0.5 parts of p-hydroxyacetophenone, 5.5 parts of 1,2-hexanediol, 3.75 parts of caprylyl glycol, 0.5 parts of angelica sinensis extract, 0.3 parts of Chinese ganoderma lucidum extract, and 0.45 parts of angelica capubescens root powder.

[0020] Component A 0.25 parts: Ligusticum chuanxiong root powder.

[0021] Component B 2.0 parts: ginseng root powder, peony root powder, Ampelopsis japonica extract, Centella asiatica extract, Astragalus membranaceus extract, ginseng root extract, honeysuckle flower extract, peony extract. Mass ratio: 1:1:1:1:1.5:1.5:1:1.

[0022] Component C 0.2 parts: Poria cocos extract.

[0023] Component D 1.0 part: Artemisia aargyi leaf extract, Atractylodes macrocephala extract, Camellia sinensis seed extract, Bletilla striata root extract. Mass ratio 1:2:2:1.

[0024] Component E 1.2 parts: Saussurea involucata extract, Iris ensata extract, pearl powder. Mass ratio 1:2:1.

[0025] The present invention also provides a method for preparing the skin care product comprising the Ganoderma lucidum composition:

[0026] (1) mixing the Chinese ganoderma lucidum extract, the Chinese angelica extract, the component A and the component B;

[0027] (2) mixing the root powder of Angelica pubescens, component C and component E;

[0028] (3) The mixture obtained in step (1), the mixture obtained in step (2) and the remaining raw materials are further stirred and mixed.

[0029] The preparation method of the angelica sinensis extract of the present invention is as follows:

[0030] After fresh angelica (without drying treatment) is sliced, ultrasonic coenzyme method is used: the enzyme amount is 10wt% of angelica, the temperature is 40°C, the time is 90min, the power is 400W, and the material-liquid ratio is 1:10 (distilled water); the obtained extract is centrifuged at 5000r / min for 15min, the supernatant is added with 4 times the volume of 95% ethanol for precipitation for 48h, and the precipitate is obtained. The drying temperature is 45°C, the drying time is 4h, and hot air drying is performed to obtain.

[0031] The ganoderma-containing composition protected by the present invention has relatively stable performance, and has good stability under large temperature differences and sunlight. In particular, the stability of angelica and peony in the formula is relatively poor, and it is also sensitive to pH. The composition provided by the present invention classifies the ingredients in the formula, adjusts the order in the preparation method, uses a macromolecular polysaccharide component to protect the unstable ingredients, and matches the oily ingredients for further protection, and uses the emulsifying component for coordination, so as to achieve stability while also achieving the best efficacy effect.

[0032] The following is an illustration using specific embodiments.

[0033] Example 1

[0034] The present embodiment provides a composition containing Ganoderma lucidum, which contains, in parts by mass: 8 parts of honey, 56 parts of glycerin, 0.5 parts of p-hydroxyacetophenone, 5.5 parts of 1,2-hexanediol, 3.75 parts of caprylyl glycol, 0.5 parts of angelica sinensis extract, 0.3 parts of Chinese Ganoderma lucidum (GANODERMA SINENSIS) extract, and 0.45 parts of angelica capubescens root powder.

[0035] Component A 0.25 parts: Ligusticum chuanxiong root powder.

[0036] Component B 2.0 parts: ginseng root powder, peony root powder, Ampelopsis japonica extract, Centella asiatica extract, Astragalus membranaceus extract, ginseng root extract, honeysuckle flower extract, peony extract. Mass ratio: 1:1:1:1:1.5:1.5:1:1.

[0037] Component C 0.2 parts: Poria cocos extract.

[0038] Component D 1.0 part: Artemisia aargyi leaf extract, Atractylodes macrocephala extract, Camellia sinensis seed extract, Bletilla striata root extract. Mass ratio 1:2:2:1.

[0039] Component E 1.2 parts: Saussurea involucata extract, Iris ensata extract, pearl powder. Mass ratio 1:2:1.

[0040] The preparation method of the angelica sinensis extract is as follows:

[0041] After fresh angelica (without drying treatment) is sliced, ultrasonic coenzyme method is used: the enzyme amount is 10wt% of angelica, the temperature is 40°C, the time is 90min, the power is 400W, and the material-liquid ratio is 1:10 (distilled water); the obtained extract is centrifuged at 5000r / min for 15min, the supernatant is added with 4 times the volume of 95% ethanol for precipitation for 48h, and the precipitate is obtained. The drying temperature is 45°C, the drying time is 4h, and hot air drying is performed to obtain.

[0042] This embodiment also provides a method for preparing the skin care product containing the Ganoderma lucidum composition:

[0043] (1) mixing the Chinese ganoderma lucidum extract, the Chinese angelica extract, the component A and the component B;

[0044] (2) mixing the root powder of Angelica dahurica (ANGELICAPUBESCENS), component C and component E;

[0045] (3) The mixture obtained in step (1), the mixture obtained in step (2) and the remaining raw materials are further stirred and mixed.

[0046] Example 2

[0047] The present embodiment provides a composition containing Ganoderma lucidum, which contains, in parts by mass: 8 parts of honey, 56 parts of glycerin, 0.5 parts of p-hydroxyacetophenone, 5.5 parts of 1,2-hexanediol, 3.75 parts of caprylyl glycol, 0.5 parts of angelica sinensis extract, 0.3 parts of Chinese Ganoderma lucidum (GANODERMA SINENSIS) extract, and 0.45 parts of angelica capubescens root powder.

[0048] Component A 0.25 parts: Ligusticum chuanxiong root powder.

[0049] Component B 2.0 parts: ginseng root powder, peony root powder, ampelopsis japonica extract, centella asiatica extract, astragalus membraneaceus extract, ginseng root extract, honeysuckle flower extract, peony extract. Mass ratio: 1:1:1:1:1.5:1.5:1:1.

[0050] Component C 0.2 parts: Poria cocos extract.

[0051] Component D 1.0 part: Artemisia algida leaf extract, Atractylodes macrocephala extract, Camellia sinensis seed extract, Bletilla striata root extract. Mass ratio 1:2:2:1.

[0052] Component E 1.2 parts: extract of snow lotus (SAUSSUREA INVOLUCRATA), extract of iris enSATA, pearl powder. Mass ratio 1:2:1.

[0053] The ANGELICA SINENSIS extract is commercially available.

[0054] This embodiment also provides a method for preparing the skin care product containing the Ganoderma lucidum composition:

[0055] (1) Mixing the Chinese Ganoderma lucidum extract, the Chinese Angelica sinensis extract, the component A and the component B;

[0056] (2) mixing the root powder of Angelica pubescens, component C and component E;

[0057] (3) The mixture obtained in step (1), the mixture obtained in step (2) and the remaining raw materials are further stirred and mixed.

[0058] Example 3

[0059] The present embodiment provides a composition containing Ganoderma lucidum. In parts by mass, the composition contains: 8 parts of honey, 56 parts of glycerin, 0.5 parts of p-hydroxyacetophenone, 5.5 parts of 1,2-hexanediol, 3.75 parts of caprylyl glycol, 0.3 parts of Chinese Ganoderma lucidum (GANODERMASINENSIS) extract, and 0.45 parts of ANGELICA PUBESCENS root powder.

[0060] Component A 0.25 parts: Ligusticum chuanxiong root powder.

[0061] Component B 2.0 parts: ginseng root powder, peony root powder, ampelopsis japonica extract, centella asiatica extract, astragalus membraneaceus extract, ginseng root extract, honeysuckle flower extract, peony extract. Mass ratio: 1:1:1:1:1.5:1.5:1:1.

[0062] Component D 1.0 part: Artemisia algida leaf extract, Atractylodes macrocephala extract, Camellia sinensis seed extract, Bletilla striata root extract. Mass ratio 1:2:2:1.

[0063] Component E 1.2 parts: extract of snow lotus (SAUSSUREA INVOLUCRATA), extract of iris enSATA, pearl powder. Mass ratio 1:2:1.

[0064] This embodiment also provides a method for preparing the skin care product containing the Ganoderma lucidum composition:

[0065] (1) Mixing the Chinese Ganoderma lucidum extract, the Chinese Angelica sinensis extract, the component A and the component B;

[0066] (2) mixing the root powder of Angelica pubescens, component C and component E;

[0067] (3) The mixture obtained in step (1), the mixture obtained in step (2) and the remaining raw materials are further stirred and mixed.

[0068] Example 4

[0069] The present embodiment provides a composition containing Ganoderma lucidum, which contains, in parts by mass: 8 parts of honey, 56 parts of glycerin, 0.5 parts of p-hydroxyacetophenone, 5.5 parts of 1,2-hexanediol, 3.75 parts of caprylyl glycol, 0.5 parts of angelica sinensis extract, 0.3 parts of Chinese Ganoderma lucidum (GANODERMA SINENSIS) extract, and 0.45 parts of angelica pubescens root powder.

[0070] Component A 0.25 parts: Ligusticum chuanxiong root powder.

[0071] Component B 2.0 parts: ginseng root powder, peony root powder, ampelopsis japonica extract, centella asiatica extract, astragalus membraneaceus extract, ginseng root extract, honeysuckle flower extract, peony extract. Mass ratio: 1:1:1:1:1.5:1.5:1:1.

[0072] Component C 0.2 parts: Poria cocos extract.

[0073] Component D 1.0 part: Artemisia algida leaf extract, Atractylodes macrocephala extract, Camellia sinensis seed extract, Bletilla striata root extract. Mass ratio 1:2:2:1.

[0074] Component E 1.2 parts: pearl powder.

[0075] The preparation method of the angelica sinensis extract is as follows:

[0076] After fresh angelica (without drying treatment) is sliced, ultrasonic coenzyme method is used: the enzyme amount is 10wt% of angelica, the temperature is 40°C, the time is 90min, the power is 400W, and the material-liquid ratio is 1:10 (distilled water); the obtained extract is centrifuged at 5000r / min for 15min, the supernatant is added with 4 times the volume of 95% ethanol for precipitation for 48h, and the precipitate is obtained. The drying temperature is 45°C, the drying time is 4h, and hot air drying is performed to obtain.

[0077] This embodiment also provides a method for preparing the skin care product containing the Ganoderma lucidum composition:

[0078] (1) Mixing the Chinese Ganoderma lucidum extract, the Chinese Angelica sinensis extract, the component A and the component B;

[0079] (2) mixing the root powder of Angelica pubescens, component C and component E;

[0080] (3) The mixture obtained in step (1), the mixture obtained in step (2) and the remaining raw materials are further stirred and mixed.

[0081] Example 5

[0082] The present embodiment provides a composition containing Ganoderma lucidum, which contains, in parts by mass: 8 parts of honey, 56 parts of glycerin, 0.5 parts of p-hydroxyacetophenone, 5.5 parts of 1,2-hexanediol, 3.75 parts of caprylyl glycol, 0.5 parts of angelica sinensis extract, 0.3 parts of Chinese Ganoderma lucidum (GANODERMA SINENSIS) extract, and 0.45 parts of angelica pubescens root powder.

[0083] Component A 0.25 parts: Ligusticum chuanxiong root powder.

[0084] Component B 2.0 parts: ginseng root powder, peony root powder, ampelopsis japonica extract, centella asiatica extract, astragalus membraneaceus extract, ginseng root extract, honeysuckle flower extract, peony extract. Mass ratio: 1:1:1:1:1.5:1.5:1:1.

[0085] Component C 0.2 parts: Poria cocos extract.

[0086] Component D 1.0 part: Artemisia algida leaf extract, Atractylodes macrocephala extract, Camellia sinensis seed extract, Bletilla striata root extract. Mass ratio 1:2:2:1.

[0087] Component E 1.2 parts: extract of snow lotus (SAUSSUREA INVOLUCRATA), extract of iris enSATA, pearl powder. Mass ratio 1:2:1.

[0088] The preparation method of the angelica sinensis extract is as follows:

[0089] After fresh angelica (without drying treatment) is sliced, ultrasonic coenzyme method is used: the enzyme amount is 10wt% of angelica, the temperature is 40°C, the time is 90min, the power is 400W, and the material-liquid ratio is 1:10 (distilled water); the obtained extract is centrifuged at 5000r / min for 15min, the supernatant is added with 4 times the volume of 95% ethanol for precipitation for 48h, and the precipitate is obtained. The drying temperature is 45°C, the drying time is 4h, and hot air drying is performed to obtain.

[0090] This embodiment also provides a method for preparing the skin care product containing the Ganoderma lucidum composition: all the raw materials are stirred and mixed together.

[0091] Performance Testing

[0092] Test 1: The products prepared in Examples 1 to 5 were placed at 0°C, 25°C, and 40°C for 90 days to check the product properties; the products were placed at 0°C and 40°C for 12 hours each alternately, and the cycle was repeated twice to check the product properties. The preliminary properties of the product were: dark brown viscous paste.

[0093] Table 1 Performance test results

[0094] Example 0℃ 25℃ 40℃ Cycle experiment Example 1 constant constant constant constant Example 2 constant constant Thinning Thinning Example 3 Almost unchanged Almost unchanged Thinning Thinning, layering Example 4 Almost unchanged Almost unchanged Thinning Thinning Example 5 Thinning Thinning Thinning, layering Thinning, layering

[0095] Test 2: Human skin patch test

[0096] This experiment recruits volunteers to try the test products and uses closed patch tests to evaluate whether the composition will cause adverse reactions to human skin and the potential possibility.

[0097] Test environment: constant temperature and humidity (temperature 20℃~22℃, humidity 40%~60%)

[0098] Test time: 30min, 24h, 48h.

[0099] Skin occlusive patch test method

[0100] Volunteer requirements: 30 people selected to participate in the trial according to the subject selection criteria

[0101] Equipment: The spot tester is Finn chambers on Scanpor, with a diameter of 8mm and an area of ​​50mm 2 .

[0102] Specific operation method

[0103] The selected area shall not exceed 50mm 2 , a qualified spot test device with a depth of about 1mm. Put the test substance into the small chamber of the spot tester with an amount of about 0.020g-0.025g (solid or semi-solid) or 0.020mL-0.025mL (liquid). When the test substance is the original cosmetic product, the control well is a blank control (no substance is placed). When the test substance is a diluted cosmetic, the diluent of the cosmetic is used in the control well. Apply the spot tester with the test substance to the curved side of the subject's forearm with low-allergenic tape, and press it lightly with the palm of your hand to evenly apply it to the skin for 24 hours. Observe the skin reaction according to the standards in Table 1 30 minutes (after the indentation disappears), 24 hours and 48 hours after removing the test substance spot tester, and record the observation results.

[0104] Interpretation of skin occlusive patch test results: If more than 5 out of 30 subjects have suspected grade 1 skin reactions, or more than 2 subjects have weak grade 2 skin reactions (more than 5 subjects have grade 2 reactions in the deodorant product patch test), or any grade 3 or higher adverse skin reaction occurs, the test substance is judged to have adverse skin reactions to humans.

[0105] Table 1 Skin reaction grading standards for skin occlusive patch test

[0106]

[0107]

[0108] Table 2 Skin reaction results of subjects

[0109]

[0110] Test 3: Human body firming efficacy test

[0111] Purpose

[0112] This trial recruited subjects to try the test product and tested the facial skin with the skin elasticity test probe Cutometer MPA580 to conduct a comprehensive evaluation of the firming effect of the test product.

[0113] How to use the test product

[0114] How to use: After cleansing your face, apply an appropriate amount evenly on the entire face (avoiding the eyes and lips), apply it for 40-60 minutes and then wash it off with clean water.

[0115] Area of ​​use: Face

[0116] Test conditions

[0117] Test environment: constant temperature and humidity (temperature 20℃~22℃, humidity 40%~60%) Test instrument: Skin elasticity test probe Cutometer MPA580

[0118] Test index: RS / R7 / O1 / F4 value

[0119] Subject screening and exit criteria

[0120] 33 subjects were recruited in each group, and the final valid data were 32. The average age was 55.00±4.97 years old.

[0121] Inclusion criteria

[0122] There are at least 32 subjects aged 30 to 60 years old.

[0123] Use a skin elasticity tester to measure three times at different locations of the left and right frontal bones of the face, with an interval of three minutes between each measurement. The average R value of the left and right sides is no higher than 0.65.

[0124] Test cycle

[0125] Before the use of the test product (day 0), and 7 days after the use of the test product.

[0126] Test parts and test methods

[0127] ① After the first visit of 32 subjects, the test was explained to the subjects and they signed the informed consent form. Finally, it was ensured that at least 32 subjects were completed and the test products were distributed after the test.

[0128] ② Each time the subject visits, wash the face with the designated cleansing liquid and apply it to the face with a dry, non-chip-absorbing paper towel. Sit quietly in a constant temperature and humidity room for 30 minutes. After the meditation, the data of the instrument test will be collected for the subjects participating in the test;

[0129] ③After the test product is distributed, the researchers will explain the use of the test product to the subjects and guide the subjects to try out the test product on site, so that the test product completely covers the area to be measured. From the second visit onwards, the subjects need to bring the test product back and hand it over to the researchers for inspection, and record the subjects' usage.

[0130] Table 3 Human body firming efficacy test results

[0131]

[0132] Change rate = (data after using the product - data before not using the product) / data before not using the product * 100%

[0133] Test 4: Human moisturizing efficacy test

[0134] This trial recruits subjects to try the test product, and uses instrument testing to conduct a comprehensive evaluation of the moisturizing effect of the product.

[0135] 1.2 How to use the test product

[0136] How to use: Apply appropriate amount to the inner side of forearm until completely absorbed.

[0137] Area of ​​application: Inner forearm

[0138] Test environment: constant temperature and humidity (temperature 20°C ~ 22°C, humidity 40% ~ 60%)

[0139] Instrument: Corneometer CM825

[0140] Indicator:MMV value

[0141] A total of 32 subjects were recruited and the final valid data were 32 people.

[0142] 3.1 Test cycle

[0143] 0h (before using the product), 1h, 2h. 3.2 Test method

[0144] ① After the first visit of the 32 subjects, the test was explained to the subjects, and the subjects signed the informed consent form. The inner forearm was tested using the instrument Corneometer CM825. Qualified subjects were screened according to the requirements, and at least 30 people were guaranteed to be completed. After the test, the test products were distributed;

[0145] ② Do not use any products (cosmetics or topical drugs) on the test site 2 to 3 days before the test, and do not contact water for 1 to 3 hours. Before the test, the subjects need to clean the inner forearms of both hands. The cleaning method is to wipe it clean with dry tissue.

[0146] ③ The test area should be marked on the inner side of the forearms of both hands of the test subject. The test area should be at least 3cmx3 cm. Multiple areas can be marked on the same arm at the same time. The interval between each test area should be at least 1cm. Before the formal test, the test subject should sit quietly in a standard room for at least 20 minutes without drinking water or beverages. The forearm is exposed and placed in the test state, and remain relaxed.

[0147] Instrumental testing and clinical evaluation were performed on the subjects' arms three times before use (0h), 1h and 2h after use. Skin moisture: The Cornermeter CM825 skin moisture tester was used to test three times, and the average of the three results of the parameter MMV value was taken.

[0148] Parameter explanation: The larger the MMV value, the better the skin moisture.

[0149] Result judgment: After using the product, the MMV value of the moisture parameter in the test area increased with a significant difference, indicating that the test sample has the effect of moisturizing the skin.

[0150] Change rate = (data after using the product - data before not using the product) / data before not using the product * 100%

[0151] Table 4 Human moisturizing efficacy test results

[0152]

[0153] Test 5: Human anti-wrinkle efficacy test

[0154] How to use the test product

[0155] How to use: After cleansing in the morning and evening, take an appropriate amount of sample and apply evenly on the entire face (avoiding the eyes and lips), apply it for 40-60 minutes and then wash it off with clean water.

[0156] Area of ​​application: whole face.

[0157] Test area: facial corner area.

[0158] Test environment: constant temperature and humidity (temperature 20℃~22℃, humidity 40%~60%).

[0159] Instrument: PRIMOS-CR.

[0160] Test indicators: Wrinkle Length value wrinkle length / Wrinkle Area value wrinkle area.

[0161] Parameter explanation: WrinkleLength is the length of wrinkles. The lower the WrinkleLength is, the shorter the wrinkles at the corners of the eyes are. Wrinkle Area is the area of ​​wrinkles. The lower the Wrinkle Area is, the smaller the area of ​​wrinkles at the corners of the eyes are.

[0162] Test cycle

[0163] Before the use of the test product (day 0), and 7 days after the use of the test product.

[0164] Test parts and test methods

[0165] ① After the first visit of the 32 subjects, the test was explained to the subjects, and the subjects signed the informed consent form. The left and right corners of the eyes were photographed using the Primos instrument. Qualified subjects were screened according to the requirements, and at least 32 people were guaranteed to be completed. After the test, the test products were distributed;

[0166] ② Each time the subject visits, wash the face with the designated cleansing liquid and apply it to the face with a dry, non-chip-absorbing paper towel. Sit quietly in a constant temperature and humidity room for 30 minutes. After the meditation, the data of the instrument test will be collected for the subjects participating in the test;

[0167] ③After the test product is distributed, the researchers will explain the use of the test product to the subjects and guide the subjects to try out the test product on site, so that the test product completely covers the area to be measured. From the second visit onwards, the subjects need to bring the test product back and hand it over to the researchers for inspection, and record the subjects' usage.

[0168] Change rate = (data after using the product - data before not using the product) / data before not using the product * 100%

[0169] Table 4 Human anti-wrinkle efficacy test results

[0170]

[0171]

[0172] As attached Figure 1 As shown, Figure 1 The left picture shows the image of the wrinkles at the corners of the eyes before use, and the right picture shows the image of the wrinkles at the corners of the eyes after use.

[0173] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A composition comprising Ganoderma lucidum, characterized in that: The composition comprises: honey, glycerin, p-hydroxyacetophenone, 1,2-hexanediol, caprylyl glycol, angelica extract and Chinese ganoderma lucidum extract.

2. A composition comprising Ganoderma lucidum according to claim 1, characterized in that: The composition further comprises: Angelica sinensis root powder.

3. The composition comprising Ganoderma lucidum according to claim 1, characterized in that: The composition further comprises: Component A: Chuanxiong root powder.

4. The composition comprising Ganoderma lucidum according to claim 1, characterized in that: The composition further comprises: component B: ginseng root powder, peony root powder, ampelopsis extract, Centella asiatica extract, Astragalus membranaceus extract, ginseng root extract, honeysuckle flower extract, and peony extract.

5. The composition comprising Ganoderma lucidum according to claim 1, characterized in that: The composition further comprises: Component C: Poria cocos extract.

6. The composition comprising Ganoderma lucidum according to claim 1, characterized in that: The composition further comprises: component D: wormwood leaf extract, atractylodes macrocephala extract, tea seed extract, and bletilla striata root extract.

7. The composition comprising Ganoderma lucidum according to claim 1, characterized in that: The composition further comprises: component E: snow lotus extract, cicada flower extract, and pearl powder.

8. A skin product containing Ganoderma lucidum, characterized in that: A composition comprising any one of claims 1 to 7.

9. The composition according to any one of claims 1 to 7, characterized in that The composition is used in the field of skin care products.

10. The composition according to any one of claims 1 to 7, characterized in that The composition is used in the fields of moisturizing, nourishing, anti-wrinkle, firming and the like.

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