Formula composition and application thereof

Abstract

The invention provides a formula composition and application thereof. The formula composition provided by the invention comprises the following active ingredients in parts by weight: 20-80 parts of mulberry leaf powder, 10-40 parts of horseradish concentrated powder, 10-60 parts of a white kidney bean extract and 2-8 parts of fish collagen peptide. According to the present invention, compatibility is performed from the aspects of satiety increasing, food intake reducing, fat metabolism increasing and the like, such that the body weight is significantly controlled, including body weight reducing and body weight controlling, and the composition has good taste and can easily achieve long-term persistence. According to the invention, the formula composition is further prepared into the beverage, and the beverage not only has the function of controlling body weight, but also is higher in acceptability, wider in audience and easier to realize long-term persistence, and has an extremely good application prospect. The formula composition and / or the beverage provided by the invention can be used for preparing food or health care products for treating, preventing or controlling weight gain in mammals.

Description

Technical Field

[0001] The present invention relates to the field of nutritional products, and in particular to a formula composition and application thereof. Background Art

[0002] Maintaining a good weight can not only improve self-confidence and reduce psychological problems such as depression and anxiety, but also reduce the risk of many diseases: proper weight can reduce the incidence of cardiovascular diseases (such as coronary heart disease, hypertension, heart disease, etc.), and can also reduce the incidence of certain types of cancer (such as breast cancer, colon cancer, etc.), diabetes, bone and joint diseases (such as fractures, osteoporosis, arthritis, etc.) and respiratory diseases (such as chronic obstructive pulmonary disease, sleep apnea syndrome, etc.). At the same time, it can improve the quality of life: maintaining a proper weight helps improve the body's function and adaptability, thereby enhancing people's sense of accomplishment and satisfaction in work, study and daily life.

[0003] The key to weight control is the balance between energy intake and expenditure. When energy intake is lower than energy expenditure, it is beneficial to control and lose weight. Energy intake can be reduced by eating less high-energy foods and eating a moderate amount of foods that increase satiety, or by increasing energy expenditure and reducing calorie storage in the body through exercise, increased metabolism, accelerated fat decomposition, etc. It is difficult for most people to stick to these two weight control methods of proper diet and increased exercise for a long time, so weight control products have become a long-lasting popular product. Summary of the invention

[0004] In order to overcome the problem that the methods of controlling weight in the prior art are difficult to adhere to for a long time, the present invention provides a formula composition for controlling weight and its application, wherein the formula composition has the functions of controlling weight and maintaining weight, and the formula composition has good taste and is easy to adhere to for a long time.

[0005] The first aspect of the present invention provides a formula composition, characterized in that, based on weight, its active ingredients include: 20-80 parts of mulberry leaf powder, 10-40 parts of wasabi concentrated powder, 10-60 parts of white kidney bean extract and 2-8 parts of fish collagen peptide.

[0006] In some embodiments of the present invention, the wasabi concentrated powder is obtained by concentrating an alcohol extract of wasabi; more preferably, the isothiocyanate content thereof is not less than 1%.

[0007] In some embodiments of the present invention, the fish collagen peptide is deep-sea bream collagen peptide, and preferably the fish collagen peptide is selected from fish skin and / or fish scale.

[0008] In some embodiments of the present invention, the molecular weight of the fish collagen peptide is 500-2000Da; and / or the content of marine fish skin collagen oligopeptide powder in the fish collagen peptide is not less than 98%.

[0009] In some embodiments of the present invention, the white kidney bean extract is an alcohol extract concentrated powder, wherein the content of α-amylase inhibitory protein is not less than 75%.

[0010] Mulberry leaf powder contains a large amount of dietary fiber and minerals, which helps promote intestinal peristalsis and accelerate feces discharge; the natural ingredients in mulberry leaf powder can also suppress appetite and reduce calorie intake, thereby achieving the effect of controlling weight. At the same time, mulberry leaf powder contains a variety of ingredients that are beneficial to the human body: rich in amino acids, dietary fiber, calcium, iron, zinc, magnesium, potassium, sodium, γ-tyrosine, glutamic acid, aspartic acid, etc. The value ratio of mulberry leaf powder in the present invention can not only achieve a good effect of controlling weight, but also retain the nutritional components of mulberry leaf powder, and can also add unique flavor and color to food.

[0011] Wasabi concentrated powder contains rich isothiocyanates, especially allyl isothiocyanate, which can promote metabolism and help reduce fat accumulation; it can regulate fat metabolism, provide dietary fiber, and help the body's fat processing ability; it contains rich fat, increases satiety, thereby reducing daily intake; thus, it has the effect of controlling weight. At the same time, wasabi concentrated powder also contains rich flavonoids, which is beneficial to adjusting the taste and nutrition of the formula composition. The dosage ratio of the wasabi concentrated powder in the present invention can not only achieve the functional effect of controlling weight, but also help maintain the specific flavor and color and nutritional function of the formula composition.

[0012] White kidney bean extract is an alcohol extract concentrated powder, which is rich in α-amylase inhibitory protein. The specific glycoprotein structure in it can bind to the glycoside cleavage site on the α-amylase molecule and cause the conformational change of the α-amylase molecule, causing it to lose the ability to bind to starch glycosides, thereby leading to loss of catalytic activity, blocking the decomposition of carbohydrates in the body, reducing the body's absorption of glucose, and reducing the conversion of glucose into fat, thereby achieving the effect of controlling weight.

[0013] Fish collagen peptides, especially deep sea bream collagen peptides, can activate lipase activity, prolong the fat decomposition and metabolism process, and help control body weight; on the other hand, the fish collagen contains rich dietary fiber, low in calories, and can reduce fat accumulation, thereby achieving the effect of controlling body weight. Controlling the amount of fish collagen peptides within the above range can not only provide nutritional value, but also ensure the functional effectiveness of the composition.

[0014] In the formula composition provided by the present invention, the synergistic effect between mulberry leaf powder, wasabi concentrated powder, white kidney bean extract and fish collagen, combined with the aforementioned dosage ratio, can not only play a role in good physical weight, but also make the composition have good taste and nutritional value, achieve healthy and pleasant weight control, and be more conducive to long-term adherence, which also ensures the weight control effect of the formula composition.

[0015] In some embodiments of the present invention, the active ingredients further include, by weight: 4-15 parts of Alpinia officinalis powder, 10-60 parts of fruit and vegetable fiber powder, 2-15 parts of seaweed powder, 2-8 parts of Agaricus bisporus powder, 4-20 parts of tea powder, 2-10 parts of prickly pear cactus juice powder, and 2-8 parts of pectin.

[0016] In the present invention, Alpinia officinalis powder, fruit and vegetable fiber powder, seaweed powder, Agaricus bisporus powder, tea powder, prickly pear cactus juice powder and pectin are used to adjust the taste and enhance the flavor of the formula composition; they can also provide rich nutritional value and control costs. For example, Alpinia officinalis powder provides rich vitamins, minerals and dietary fiber, and can also adjust the taste; in addition to providing rich dietary fiber, fruit and vegetable fiber powder is also conducive to cost control; seaweed powder, Agaricus bisporus powder and tea powder can provide high nutritional value and can also make the composition maintain a unique taste and flavor; pectin is mainly used to maintain the stability of the product. The main functions of oligofructose syrup, citric acid and steviol glycosides are to achieve flavor, taste and cost control.

[0017] In some embodiments of the present invention, the tea powder is selected from at least one of black tea powder and Pu'er tea powder, and preferably the tea powder is composed of black tea powder and Pu'er tea powder in a ratio of 1:0.5-2. When the tea powder is composed of black tea powder and Pu'er tea powder in a ratio of 1:0.5-2, the tea fragrance and taste of the combined tea make people feel happy and relaxed. Therefore, when the formula composition is used to treat, prevent or control weight gain, it is easier to adhere to it for a long time, thereby achieving a better effect of controlling and maintaining weight.

[0018] The formula composition provided by the present invention is formulated in a certain proportion from the aspects of increasing satiety, reducing food intake, increasing fat metabolism, reducing fat formation, and has been experimentally verified to significantly increase satiety, reduce food intake, and increase fat metabolism, thereby achieving significant weight control and weight maintenance.

[0019] In some embodiments of the present invention, the formula composition, by weight, comprises the following raw materials: 20-80 parts of mulberry leaf powder, 10-40 parts of wasabi concentrated powder, 4-15 parts of Alpinia officinalis powder, 10-60 parts of white kidney bean extract, 10-60 parts of fruit and vegetable fiber powder, 2-8 parts of fish collagen peptide, 2-15 parts of seaweed powder, 2-8 parts of Agaricus bisporus powder, 2-10 parts of black tea powder, 2-10 parts of Pu'er tea powder, 2-10 parts of pear cactus juice powder, and 2-8 parts of pectin. The present invention optimizes the raw materials and composition ratios to obtain the formula composition. The present invention controls the dosage of the above-mentioned ingredients, which can not only ensure the effectiveness of their functions, but also maintain the stability and taste of the product.

[0020] At the same time, experiments have shown that on the basis of 20-80 parts of mulberry leaf powder, 10-40 parts of wasabi concentrated powder, 10-60 parts of white kidney bean extract, and 2-8 parts of fish collagen peptides, 4-15 parts of Alpinia galanga powder, 10-60 parts of fruit and vegetable fiber powder, 2-15 parts of seaweed powder, 2-8 parts of Agaricus bisporus powder, 4-20 parts of tea powder, 2-10 parts of prickly pear cactus juice powder, and 2-8 parts of pectin are added, and a synergistic effect is produced between the components, and the resulting formula composition has a significantly better effect of controlling and maintaining weight; in particular, the addition of prickly pear cactus juice powder with the function of blocking oil excretion, and the synergistic effect between mulberry leaf powder, wasabi concentrated powder, white kidney bean extract and fish collagen peptides is more obvious.

[0021] In some embodiments of the present invention, the formula composition, measured by weight, comprises the following raw materials: 40-60 parts of mulberry leaf powder, 20-30 parts of wasabi concentrated powder, 6-10 parts of Alpinia officinalis powder, 20-40 parts of white kidney bean extract, 20-30 parts of fruit and vegetable fiber powder, 3-5 parts of deep-sea red snapper collagen peptide, 5-10 parts of seaweed powder, 3-5 parts of Agaricus bisporus powder, 2-4 parts of black tea powder, 2-4 parts of Pu'er tea powder, 2-4 parts of pear cactus juice powder, and 2-4 parts of pectin.

[0022] The present invention has been found through experiments that when the raw materials of the formula composition are prepared in the following weight proportions: 40-60 parts of mulberry leaf powder, 20-30 parts of wasabi concentrated powder, 6-10 parts of Alpinia officinalis powder, 20-40 parts of white kidney bean extract, 20-30 parts of fruit and vegetable fiber powder, 3-5 parts of deep-sea red snapper collagen peptide, 5-10 parts of seaweed powder, 3-5 parts of Agaricus bisporus powder, 2-4 parts of black tea powder, 2-4 parts of Pu'er tea powder, 2-4 parts of pear cactus juice powder, and 2-4 parts of pectin, it has a better weight control effect.

[0023] The formula composition provided by the present invention can be prepared into various dosage forms known to those skilled in the art. Preferably, the composition is formulated into tablets, capsules, beverages, meal replacement powders or granules, etc. The specific preparation methods are mastered by those skilled in the art and the present invention does not specifically limit this.

[0024] The present invention combines ingredients from the aspects of increasing satiety, reducing food intake and increasing fat metabolism, and combines them in a certain proportion. Experimental verification shows that it can significantly increase satiety, reduce food intake and increase fat metabolism, thereby achieving significant weight control.

[0025] The present invention further prepares the formula composition into a beverage, comprising the formula composition; preferably, the mass content of the formula composition in the beverage is 50-60%; more preferably, the beverage further comprises 2000-8000 parts of citric acid, 30-120 parts of stevioside, and 30000-90000 parts of oligofructose syrup. The formula composition is prepared into a beverage, which has higher acceptance, wider audience, and excellent application prospects. The beverage provided by the present invention adopts the above-mentioned formula composition as the main ingredient, and adds preferred auxiliary materials, which can not only ensure the effectiveness of its function, but also maintain the stability of the product; at the same time, it can also have good flavor, taste and reasonable cost.

[0026] The method for preparing the beverage provided by the present invention comprises the following steps: (1) Mix the active ingredients in the formula amount with citric acid and steviol glycosides and sieve; (2) Add the formulated amount of oligofructose syrup and an appropriate amount of solvent, mix well, sterilize at 105-115°C for 15-30 seconds, and aseptically package after cooling.

[0027] The formula composition and / or the beverage of the present invention can be used for controlling body weight, such as reducing body weight, maintaining body weight, etc. Therefore, the present invention also provides the use of the composition and / or the beverage in the manufacture of food or health products for treating, preventing or controlling weight gain in mammals; preferably, the mammal is a human.

[0028] The formula composition provided by the present invention has healthy and safe raw materials, clear and significant functions, and has wide promotion and applicability.

[0029] The present invention is compatible from several aspects such as increasing satiety, reducing food intake and increasing fat metabolism, and is combined in a certain proportion. After experimental verification, the effect of each component in controlling weight is synergistically enhanced. Intake of the formula composition provided by the present invention can significantly increase satiety, reduce food intake, and increase fat metabolism, thereby achieving significant weight control, and can achieve weight loss and weight maintenance; at the same time, it can increase nutrition, and has a good taste, and is easy to adhere to for a long time, providing a new experience for people who need to control weight, and can easily achieve long-term adherence, thereby achieving the purpose of controlling weight and maintaining weight, while maintaining good health or even making the body healthier. After the formula composition is further made into a beverage, it has a higher acceptance, a wider audience, and is easier to achieve long-term adherence, and has excellent application prospects. DETAILED DESCRIPTION

[0030] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described in conjunction with specific embodiments below. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] Unless otherwise specified, all components used in the following examples are known commercially available products. The preparation methods and source information of some raw materials are shown in the following table. When the raw materials involve multiple limitations, the specific embodiments can choose one method to meet the required conditions, or all of them can be met.

[0032]

[0033] Example 1

[0034] This embodiment provides a formula composition, and its formula composition is: Main ingredients: 60 mg mulberry leaf powder, 25 mg wasabi concentrated powder, 8 mg alpinia powder, 25 mg white kidney bean extract, 25 mg fruit and vegetable fiber powder, 4 mg deep sea red snapper collagen peptide, 6 mg seaweed powder, 4 mg Agaricus bisporus powder, 2 mg black tea powder, 2 mg Pu'er tea powder, 2 mg pear cactus juice powder, 4 mg pectin.

[0035] At the same time, this embodiment makes the formula composition into a beverage, including the formula composition, and also includes a nutritionally acceptable carrier or excipient and water. Specifically, the formula of the beverage is: 60 mg of mulberry leaf powder, 25 mg of wasabi concentrated powder, 8 mg of Alpinia officinalis powder, 25 mg of white kidney bean extract, 25 mg of fruit and vegetable fiber powder, 4 mg of deep-sea red snapper collagen peptide, 6 mg of seaweed powder, 4 mg of Agaricus bisporus powder, 2 mg of black tea powder, 2 mg of Pu'er tea powder, 2 mg of pear cactus juice powder, 4 mg of pectin, 4 g of citric acid, 90 mg of steviol glycosides, 60 g of oligofructose syrup and 1 liter of water.

[0036] The beverage preparation method comprises the following steps: uniformly mixing the powder materials in the formula amount, sieving, adding 1 liter of water and 60 grams of oligofructose syrup and mixing, sterilizing at a temperature of 105-115° C. for 15-30 seconds, cooling and aseptically filling.

[0037] Example 2

[0038] The present embodiment provides a beverage, which is different from the embodiment 1 in that the beverage formula is as follows: 55 mg of mulberry leaf powder, 20 mg of wasabi concentrated powder, 6 mg of Alpinia officinalis powder, 20 mg of white kidney bean extract, 20 mg of fruit and vegetable fiber powder, 3 mg of deep sea red snapper collagen peptide, 5 mg of seaweed powder, 3 mg of Agaricus bisporus powder, 3 mg of black tea powder, 3 mg of Pu'er tea powder, 5 mg of prickly pear cactus juice powder, 5 mg of pectin, 5 g of citric acid, 80 mg of stevioside, 50 g of oligofructose syrup and 1 liter of water.

[0039] Example 3

[0040] The present embodiment provides a beverage, which is different from the embodiment 1 in that the beverage has the following formula: 50 mg of mulberry leaf powder, 20 mg of wasabi concentrated powder, 7 mg of Alpinia officinalis powder, 22 mg of white kidney bean extract, 23 mg of fruit and vegetable fiber powder, 5 mg of deep sea red snapper collagen peptide, 7 mg of seaweed powder, 7 mg of Agaricus bisporus powder, 5 mg of black tea powder, 5 mg of Pu'er tea powder, 6 mg of prickly pear cactus juice powder, 4 mg of pectin, 7 g of citric acid, 85 mg of stevioside, 55 g of oligofructose syrup and 1 liter of water.

[0041] Test case: Weight control function test

[0042] The beverage in Example 1 was used as a test sample.

[0043] Animal strain: SD; Experimental animal grade: SPF grade; Gender and number: SD (male, 50); Animal age: 6 weeks old; Animal weight range: 160g; Individual animal marking: Ear piercing number 2901-2950#.

[0044] A blank control group, a model control group, a test article low-dose group, a test article medium-dose group, and a test article high-dose group were set up, with 10 rats in each group. The ear numbers of the blank control group were 2901-2910, the ear numbers of the model control group were 2911-2920, the ear numbers of the test article low-dose group were 2921-2930, the ear numbers of the test article medium-dose group were 2931-2940, and the ear numbers of the test article high-dose group were 2941-2950.

[0045] Add 15.0% sucrose, 15.0% lard, appropriate amount of casein, calcium hydrogen phosphate, stone powder, etc. to the maintenance feed. In addition to crude fat, the moisture, crude protein, crude fat, crude fiber, crude ash, calcium, phosphorus, calcium: phosphorus of the model feed must meet the national standards for maintenance feed.

[0046] Obesity prevention model method. Rats were fed maintenance feed under the barrier system and observed for 7 days. After the adaptation period, the rats were weighed, and serum was taken to test blood sugar and blood lipids (fasting for 4-6 hours before blood collection). According to the test indicators, they were divided into 5 groups, 10 rats were given maintenance feed as a blank control group, and 40 rats were given high-calorie feed, divided into a model control group, a low-dose group of the test sample, a medium-dose group of the test sample, and a high-dose group of the test sample. The low-dose group of the test sample was gavaged with the beverage in Example 1, and the medium-dose group and the high-dose group of the test sample were gavaged with a 5-fold concentrated solution of the beverage in Example 1. According to different groups, the corresponding control and test samples were given, and the gavage capacity was low-dose group: 1.043 mL / 100g gavage once a day; medium-dose group: 1.043 mL / 100g gavage once a day; high-dose group: 1.043 mL / 100g gavage twice a day, with an interval of about 6 hours between gavages; gavage time was 10 weeks.

[0047] Observation indicators: body weight, weight gain. See Table 1-2 for specific results.

[0048]

[0049] As can be seen from Table 1-2, in the 1st to 4th week, compared with the blank control group, there was no significant difference in the body weight of the rats in the model control group; the test sample medium dose group showed a significant decrease in body weight compared with the blank control group and the model group (P < 0.01), and the test sample high dose group showed a significant decrease in body weight compared with the blank control group and the model group (P < 0.01). In the 5th to 10th week, compared with the blank control group, the body weight of the rats in the model control group increased significantly (P < 0.05); the test sample medium dose group showed a significant decrease in body weight compared with the model group (P < 0.01). In summary, the beverage provided in Example 1 has a significant inhibitory effect on the weight gain of animals on a high-energy diet.

[0050] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments may still be modified, or some of the technical features may be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A formula composition, characterized in that: The active ingredients include, by weight: 20-80 parts of mulberry leaf powder, 10-40 parts of wasabi concentrated powder, 10-60 parts of white kidney bean extract and 2-8 parts of fish collagen peptide.

2. The composition according to claim 1, characterized in that The wasabi concentrated powder is an alcohol extract concentrated powder; preferably, the isothiocyanate content thereof is not less than 1%.

3. The composition according to claim 1 or 2, characterized in that The fish collagen peptide is a deep-sea porgy collagen peptide, preferably the fish collagen peptide is selected from fish skin and / or fish scale; the molecular weight of the fish collagen peptide is 500-2000Da; and / or the content of marine fish skin collagen oligopeptide powder in the fish collagen peptide is not less than 98%; And / or, the white kidney bean extract is an alcohol extract concentrated powder, wherein the content of α-amylase inhibitory protein is not less than 75%.

4. The composition according to any one of claims 1 to 3, characterized in that By weight, the active ingredients also include: 4-15 parts of Alpinia officinalis powder, 10-60 parts of fruit and vegetable fiber powder, 2-15 parts of seaweed powder, 2-8 parts of Agaricus bisporus powder, 4-20 parts of tea powder, 2-10 parts of prickly pear cactus juice powder, and 2-8 parts of pectin.

5. The composition according to claim 4, characterized in that The tea powder is selected from at least one of black tea powder and Pu'er tea powder.

6. The composition according to claim 5, characterized in that The tea powder is composed of black tea powder and Pu'er tea powder in a ratio of 1:0.5-2.

7. The composition according to claim 1, characterized in that By weight, the raw materials include: 40-60 parts of mulberry leaf powder, 20-30 parts of wasabi concentrated powder, 6-10 parts of Alpinia officinalis powder, 20-40 parts of white kidney bean extract, 20-30 parts of fruit and vegetable fiber powder, 3-5 parts of deep-sea red snapper collagen peptide, 5-10 parts of seaweed powder, 3-5 parts of Agaricus bisporus powder, 2-4 parts of black tea powder, 2-4 parts of Pu'er tea powder, 2-4 parts of pear cactus juice powder, and 2-4 parts of pectin.

8. The composition according to any one of claims 1 to 7, characterized in that The composition is formulated into tablets, capsules, beverages, meal replacement powders or granules.

9. A beverage, characterized in that Comprising the formula composition according to any one of claims 1 to 8; preferably, the mass content of the formula composition in the beverage is 50-60%; more preferably, the beverage also includes 2000-8000 parts of citric acid, 30-120 parts of steviol glycosides, and 30000-90000 parts of oligofructose syrup.

10. Use of the formula composition according to any one of claims 1 to 8 and / or the beverage according to claim 9 in the manufacture of a food or health product for treating, preventing or controlling weight gain in a mammal; preferably the mammal is a human.

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