AI-based Hair Follicle Drug Screening and Detection Device

Abstract

The present invention discloses an AI-based hair follicle drug screening and detection device, belonging to the field of drug screening and detection. The AI-based hair follicle drug screening and detection device includes a storage pool, an optical detection module, and transmission pipes on both sides of the storage pool. A bidirectional threaded rod is provided at the upper end of the storage pool, and a first transmission frame is provided on both sides outside the optical detection module. The present invention solves the problem that in the existing drug screening device, during the screening process, the simultaneous connection between the rotating and flowing pool and the pipe sleeve will cause deformation and damage to the sleeve, affect the sealing performance of the device, and reduce the service life of the device. In the present invention, the rotation of the transmission block first drives the bidirectional threaded rod to rotate, so that the transmission pipe is disconnected from the connecting pipe. As the transmission block continues to rotate, it drives the gear and the transmission rod to rotate. The rotation of the transmission rod can cause the storage pool to flip to achieve the pouring and cleaning of the medicament. The rotation of the storage pool and the extraction of the transmission pipe are divided into two steps, avoiding damage to the transmission pipe.

Description

Technical Field

[0001] The present invention relates to the field of drug screening and detection, and specifically to an AI-based hair follicle drug screening and detection device. Background Technique

[0002] A drug screening and detection device is a device specifically used to quickly and accurately screen out drug molecules with potential pharmacological activities or specific biological effects from a large number of candidate compounds. It integrates advanced chemistry, biology, informatics, and automation technologies, and can simulate the drug action environment in vivo, evaluate compounds with high throughput and high efficiency, thereby accelerating the new drug R & D process, reducing R & D costs, and increasing the success rate of new drug discovery;

[0003] Chinese Patent with Publication No. CN109916815B discloses a drug screening device based on SPR, including a rotating cylinder frame. The rotating cylinder frame is rotatably connected to a fixed shaft, and the rotating cylinder frame is distributed with nested installation grooves arranged in a circumferential distribution. A flow cell is nested in the nested installation groove. By providing a rotating cylinder frame for fixing the circumferentially distributed flow cells and a Geneva mechanism, the replacement of the flow cell is realized, and thus the replacement of the target molecule is realized, improving the efficiency of drug screening. And by providing a left connecting joint, a right connecting joint, a sliding block, and a bidirectional lead screw, it is convenient to connect and disconnect the flow cell and the connecting joint, and convenient to synchronously replace the flow cell.

[0004] During the screening process of the drug screening device of the above patent, due to transmission, when the flow cell is connected to the joint, the rotating cylinder frame will also drive the flow cell to rotate at the same time. The simultaneous rotation and the connection between the flow cell and the sleeve will cause the sleeve to deform and be damaged, affecting the sealing performance of the device and reducing the service life of the device. Summary of the Invention

[0005] The purpose of the present invention is to provide an AI-based hair follicle drug screening and detection device. By rotating the transmission block to first drive the bidirectional threaded rod to rotate, the transmission pipe is disconnected from the connecting pipe. As the transmission block continues to rotate, it drives the gear and the transmission rod to rotate. The rotation of the transmission rod can cause the storage pool to flip to achieve the pouring and cleaning of the medicament. The rotation of the storage pool and the extraction of the transmission pipe are divided into two steps, avoiding damage to the transmission pipe, and solving the problems raised in the above background technique.

[0006] To achieve the above object, the present invention provides the following technical solution: An AI-based hair follicle drug screening and detection device, including a storage pool, an optical detection module, and transfer pipes on both sides of the storage pool. A bidirectional threaded rod is provided at the upper end of the storage pool. The counterclockwise rotation of the bidirectional threaded rod can simultaneously generate relative movement inside the second transmission frame. After being restricted by the upper end inside the housing of the hair follicle drug screening and detection device, the second transmission frame is changed from a rotational motion to a horizontal linear motion. By rotating the bidirectional threaded rod, the two transfer pipes can be simultaneously pulled out from the connecting pipe. While pulling out, by rotating the bidirectional threaded rod clockwise, the transfer pipes can be reset and clamped on both sides outside the connecting pipe, enabling the materials transported inside the transfer pipes to be transported into the storage pool for drug screening and detection. On both sides outside the optical detection module, a first transmission frame is provided. After the transfer pipes are moved away from the storage pool by the transmission group and then the first transmission frame rotates, the transmission group includes a transmission rod, a gear, a transmission block, a tooth groove, and a synchronous belt for connecting the gear and the transmission rod. Half of the circle of the transmission block is provided with a tooth groove. By reducing the tooth groove provided on half of the circle, after the transmission block is started, it will not drive the gear to rotate immediately. After the output, the transmission block will first drive the transfer pipes to adjust their positions, and the tooth groove is meshed with the gear.

[0007] Preferably, the transmission block is welded to one side of the bidirectional threaded rod, and the transmission rod is welded to one side of the first transmission frame. When the storage pool is located above the optical detection module, the tooth groove outside the transmission block is located on one side above the gear. When the transmission block rotates and the tooth groove contacts the gear, it will drive the gear to rotate clockwise. By adjusting the rotation of the transmission block, the storage pool can be flipped. During the flipping process of the storage pool, the reagent materials for detection inside the storage pool can be poured out. After the storage pool rotates and finally flips, it can be cleaned. Subsequently, by adjusting the rotation direction of the transmission block to make it rotate clockwise, the transmission block will first drive the storage pool to flip and reset. Since only half of the circle of the transmission block is provided with a tooth groove, the clockwise rotation of the transmission block will first drive the transmission block to flip. After flipping, due to the absence of the tooth groove, the transmission block will not drive the storage pool to flip. As the transmission block continues to rotate, the transfer pipes are reset and inserted into the connecting pipe again.

[0008] Preferably, the bidirectional threaded rod rotates to drive the transfer pipes to move horizontally through threaded cooperation with the second transmission frame. Both sides of the storage pool are hermetically connected to the transfer pipes through connecting pipes. The horizontal movement of the second transmission frame can adjust the connection state between the transfer pipes and the connecting pipes. The outside of the transfer pipes is fixed to the lower end inside the second transmission frame. After horizontally adjusting the position of the second transmission frame, the second transmission frame can pull out the transfer pipes from outside the connecting pipes. Similarly, the second transmission frame can clamp the transfer pipes outside the connecting pipes.

[0009] Preferably, a connecting block with the same weight as the storage pool is arranged at the lower end of the optical detection module. The first transmission frame is fixed to the outer walls of the storage pool and the connecting block respectively by bolts. The connecting block can offset the weight of the storage pool, preventing the weight of the storage pool from causing the transmission rod to rotate easily and avoiding poor stability of the storage pool. The storage pool fixed by bolts facilitates the user to replace the storage pool. After long-term use, the user can unfold the outer wall of the hair follicle drug screening and detection device. Unfolding the outer wall will expose the storage pool, and then the user can manually disassemble and replace the storage pool.

[0010] Preferably, a lower storage frame is arranged at the lower end of the connecting block. An adjustable spraying component is arranged on the lower storage frame facing the storage pool. A hot air blower is arranged on one side of the upper end of the adjustable spraying component. The hot air blower can dry the connecting block to prevent the damp connecting block from affecting the subsequent injection of the medicament. The lower storage frame can support the adjustable spraying component, and this support can also make the position of the adjustable spraying component face the storage pool to spray pure water, enabling the pure water to directly and comprehensively clean the storage pool. Comprehensive cleaning is convenient for subsequent screening and detection of various medicaments.

[0011] Preferably, a fixed disk with exhaust holes is arranged on the side of the hot air blower facing the adjustable spraying component. The exhaust holes face the storage pool and are hermetically connected to the hot air blower. The storage pool will be flipped to the upper end of the fixed disk after being driven by the transmission group. The exhaust holes directly exhaust air towards the flipped storage pool to dry the cleaned storage pool. The fixed disk can slide horizontally with a push. When moving horizontally and wrapping around the upper end of the adjustable spraying component, it can cover the flipped storage pool while wrapping around the upper end of the adjustable spraying component, enabling the high-temperature gas discharged from the inside of the fixed disk to quickly and closely contact the internal cleaning position of the storage pool, and can directly perform efficient drying after cleaning the storage pool.

[0012] Preferably, the hot air blower is driven by a unidirectional threaded rod for horizontal position adjustment. Only after the rotation of the unidirectional threaded rod restricts and fixes the hot air blower on the outer shell of the hair follicle drug screening and detection device can the cleaned storage pool rotate, preventing the protruding fixed disk from affecting the normal rotation of the storage pool.

[0013] Preferably, drainage holes are arranged on both sides of the front end of the storage pool. The reserved drainage holes enable the medicament to be discharged from the drainage holes during the rotation of the storage pool when it rotates and adjusts its orientation. The medicament does not need to be discharged only after the storage pool is flipped, avoiding splashing caused by the unified discharge of all medicaments and also preventing the medicament from being discharged into the inside of the adjustable spraying component, which may affect the pure water discharged from the position of the adjustable spraying component subsequently.

[0014] Preferably, the liquid level of the medicament transported into the storage tank by the transfer pipe is not higher than the liquid discharge hole, and the medicament transported by the transfer pipe is located below the liquid discharge hole, so as to prevent the medicament from flowing out directly from the position of the liquid discharge hole. The liquid discharge hole can pre-emptively discharge the medicament inside the storage tank during the inversion of the storage tank, so that the medicament can be pre-poured into the lower receiving frame.

[0015] Preferably, the adjustable spraying assembly includes: an outer ring bracket and an inner ring bracket, which are connected by a plurality of groups of connecting brackets. A plurality of groups of inner ring fan blades are installed inside the inner ring bracket, and a plurality of groups of inner ring fan blades are installed between the outer ring bracket and the inner ring bracket. The driving motor is fixedly arranged on the outer wall of the outer ring bracket, and a driving gear is fixedly sleeved on the output shaft of the driving motor. The annular driving member is movably sleeved on the outer wall of the outer ring bracket, and the annular driving member is connected to the outer ring bracket by a thread. A plurality of groups of meshing teeth are arranged on the outer wall of the annular driving member, and the driving gear meshes with the plurality of groups of meshing teeth. A plurality of groups of supporting members are fixedly arranged around the outer wall of the outer ring bracket, and the same first rotating bearing is installed in each group of supporting members. The first rotating connecting member is connected to the outer ring bracket through the first rotating bearing, and one end of the first rotating connecting member extends out of the first rotating bearing and is fixedly connected to the driving connecting rod. The other end of the first rotating connecting member is fixedly connected to the outer ring fan blade. The end of the driving connecting rod away from the first rotating bearing is movably connected to the outer wall of the annular driving member. A plurality of groups of supporting grooves and through holes are formed on the inner ring bracket, and each group of supporting grooves and through holes are coaxially arranged. The same second rotating bearing is installed in each group of supporting grooves. The second rotating connecting member is movably connected to the inner ring bracket through the second rotating bearing. One end of the second rotating connecting member extends out of the second rotating bearing and is fixedly connected to the outer ring fan blade. The other end of the second rotating connecting member passes through the through hole and is fixedly connected to the inner ring fan blade. The outer ring fan blade and the inner ring fan blade on the same axis are arranged perpendicular to each other.

[0016] Preferably, it further includes: a tension sensor, arranged on the synchronous belt, for monitoring the tension level of the synchronous belt during use;

[0017] A laser alignment sensor, arranged on the inner wall of the detection device housing and on the same axis as the synchronous belt, for monitoring the offset of the synchronous belt during use;

[0018] A temperature sensor, arranged inside the detection device housing, for monitoring the ambient temperature when the synchronous belt is working;

[0019] A rotational speed sensor one, arranged on the transmission rod, for monitoring the rotational speed of the transmission rod;

[0020] A rotational speed sensor two, arranged on the transmission block, for monitoring the rotational speed of the transmission block;

[0021] A timer, arranged on the outer surface of the detection device, for monitoring the usage duration of the detection device;

[0022] An alarm, and the alarm is arranged on the outer surface of the detection device;

[0023] A controller, and the controller is arranged on the outer surface of the housing of the detection device. The controller is electrically connected to a tension sensor, a laser alignment sensor, a temperature sensor, a first rotational speed sensor, a second rotational speed sensor, a timer and the alarm respectively. The controller controls the alarm to work based on the tension sensor, the laser alignment sensor, the temperature sensor, the first rotational speed sensor, the second rotational speed sensor and the timer, including:

[0024] Step 1: The controller calculates the strain state coefficient of the synchronous belt during use based on the tension sensor, the laser alignment sensor, the timer, the first rotational speed sensor, the second rotational speed sensor and formula (1):

[0025]

[0026] Wherein, X is the strain state coefficient of the synchronous belt during use, F1 is the detected value of the tension sensor, F2 is the maximum tension that the synchronous belt can withstand preset, n1 is the detected value of the first rotational speed sensor, n2 is the detected value of the second rotational speed sensor, L1 is the detected value of the laser alignment sensor, R1 is the radius of the transmission rod, R2 is the radius of the output shaft of the motor that drives the transmission block to rotate, s is the detected value of the timer, μ1 is the friction coefficient of the synchronous belt, θ is the Poisson's ratio of the synchronous belt material, S1 is the contact area between the synchronous belt and the transmission rod, E is the shear modulus of the synchronous belt, and ln is the natural logarithm with e as the base;

[0027] Step 2: Based on Step 1, the controller calculates the life index of the synchronous belt based on the temperature sensor and formula (2):

[0028]

[0029] Wherein, Y is the life index of the synchronous belt, is the maximum wear amount of the synchronous belt preset, T1 is the detected value of the temperature sensor, T2 is the current ambient temperature, K is the product of the accuracies of the tension sensor, the laser alignment sensor, the temperature sensor, the first rotational speed sensor, the second rotational speed sensor and the timer, Δ1 is the preset damage coefficient of the synchronous belt, and e is the natural constant with a value of 2.72;

[0030] Step 3: The controller compares the life index of the synchronous belt calculated in Step 2 with the preset life index. When the life index of the synchronous belt calculated in Step 2 is less than the preset life index, the controller controls the alarm to give an alarm prompt.

[0031] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0032] 1. During the process that the transmission block rotates and drives the transmission pipe to be pulled out from both sides of the storage tank by the bidirectional threaded rod, there are no circumferentially distributed tooth grooves on one side of the outer part of the transmission block, so it cannot drive the gear to rotate. As the transmission block continues to rotate counterclockwise, the transmission block will drive the gear to rotate through the tooth grooves. After the rotation of the gear is transmitted through the synchronous belt and the transmission rod, it will drive the storage tank that pulls out the transmission pipe to rotate. After being driven and rotated, the transmission block can successively realize the pulling out of the transmission pipe and the rotation of the storage tank, avoiding damage to the connection position between the transmission pipe and the connecting pipe caused by simultaneous operation. After the transmission block rotates counterclockwise by 360 degrees once to successively realize the pulling out of the transmission pipe and the flipping of the storage tank, the transmission block rotates clockwise to realize that after the storage tank is flipped, the transmission pipe is inserted into the connecting pipes on both sides of the storage tank. The operation is simple and can improve the service life of the equipment, avoiding the need to frequently replace the connection position between the transmission pipe and the connecting pipe.

[0033] 2. During the flipping process of the storage tank of the present invention, due to the flipping, the liquid at the lower end of the storage tank will flow towards the drain hole and be discharged to the outside of the storage tank through the drain hole and then fall into the lower receiving frame. By flipping the storage tank, the medicine inside the storage tank can be actively poured out, improving the cleaning effect of the storage tank and avoiding the poured medicine from filling outside the adjustable spraying component. On the other hand, as the storage tank rotates, the storage tank can be aligned with the adjustable spraying component. The liquid sprayed by the adjustable spraying component will actively clean the storage tank, and after cleaning, the hot air blower is started to discharge high-temperature gas from the exhaust hole position, actively drying the inside of the storage tank, cleaning the storage tank efficiently and quickly, facilitating the subsequent input, screening and detection of medicine. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 is the front view of the overall external structure of the present invention;

[0035] Figure 2 is the side view of the positional relationship of the fixed disk of the present invention;

[0036] Figure 3 is the schematic diagram of the gear transmission structure of the present invention;

[0037] Figure 4 is the schematic diagram of the positional relationship of the tooth grooves of the present invention;

[0038] Figure 5 is the exploded view of the connection relationship between the transmission pipe and the storage tank of the present invention;

[0039] Figure 6 is the schematic diagram of the transmission structure of the storage tank and the connecting block of the present invention;

[0040] Figure 7Schematic structure of the adjustable spray assembly of the present invention Figure 1 ;

[0041] Figure 8 Schematic structure of the adjustable spray assembly of the present invention Figure 2 ;

[0042] Figure 9 Schematic structure of the adjustable spray assembly of the present invention Figure 3 ;

[0043] In the figure: 1, the first transmission frame; 2, the storage pool; 3, the lower storage frame; 4, the adjustable spray assembly; 5, the transmission rod; 6, the gear; 7, the transmission block; 8, the bidirectional threaded rod; 9, the second transmission frame; 10, the transmission pipe; 11, the fixed disk; 12, the hot air blower; 13, the unidirectional threaded rod; 14, the liquid discharge hole; 16, the exhaust hole; 18, the tooth groove; 21, the connecting pipe; 22, the connecting shaft; 23, the connecting block; 24, the synchronous belt; 25, the outer ring bracket; 26, the inner ring bracket; 27, the inner ring fan blade; 28, the connecting bracket; 29, the outer ring fan blade; 30, the waterproof housing; 31, the drive motor; 32, the drive gear; 33, the annular drive member; 34, the meshing teeth; 35, the first rotating bearing; 36, the drive connecting rod; 37, the first rotating connecting member; 38, the supporting member; 39, the second rotating connecting member; 40, the second rotating bearing; 41, the supporting groove; 42, the through hole. Specific embodiments

[0044] The present invention will be further described below in conjunction with specific embodiments.

[0045] Embodiment 1

[0046] As Figure 1 shown, the AI-based follicular drug screening and detection device of this embodiment includes a storage pool 2, transmission pipes 10 on both sides of the storage pool 2 for transmitting medicaments, and a transmission group for driving the storage pool 2 to rotate. After the follicular drug liquid is extracted, it will be stored inside the storage pool 2 during detection. The optical detection module provided at the lower end of the storage pool 2 will detect the follicular drug liquid and calculate the data through the AI module built in the follicular drug screening and detection device, perform curve fitting after calculation, and judge the drug effectiveness;

[0047] On both sides of the storage pool 2, there are barrel-shaped structures that can store the medicament. Just pour the medicament to be detected into the barrel-shaped structures in advance, and then directly extract the medicament inside the barrel-shaped structures to transport the medicament to the storage pool 2. The medicaments on both sides can be proportioned according to the extracted amount to realize the testing of more proportioned medicaments, which is more conducive to AI calculation and exclusion of the solutions that do not need to be detected. Moreover, the barrel-shaped structures on both sides can also be used alternately. When the user has used up the medicament in one of the barrel-shaped structures and is cleaning the barrel-shaped structure, the medicament can be directly loaded into the other barrel-shaped structure for extraction to achieve continuous detection. When cleaning the barrel-shaped structure, the device does not need to stop detection, and the two barrel-shaped structures can also be used alternately to adapt to the long-term high-frequency AI screening of medicaments;

[0048] Wherein, on both sides outside the storage pool 2, there are second transmission frames 9 for fixing the transmission pipe 10. A bidirectional threaded rod 8 runs through between the two second transmission frames 9. The threaded wall outside the bidirectional threaded rod 8 is in threaded cooperation with the through position of the second transmission frame 9. The upper end of the second transmission frame 9 is slidably connected to the card slot of the outer shell of the hair follicle drug screening and detection device. After being restricted, the rotation of the bidirectional threaded rod 8 will drive the two second transmission frames 9 to move relatively;

[0049] Specifically in this embodiment, as Figure 5 shown, on both sides of the storage pool 2 facing the transmission pipe 10, there are connection pipes 21 sealed. The connection pipes 21 are in card slot connection with the transmission pipe 10. Through the lateral sliding of the second transmission frame 9, the transmission pipe 10 can be stuck outside the connection pipe 21, or through the lateral sliding of the second transmission frame 9, the transmission pipe 10 can be separated from the connection pipe 21;

[0050] The medicament liquid transmitted at the position of the connection pipe 21 can directly fall to the lower end inside the storage pool 2. After the medicament is transported into the storage pool 2, the medicament does not contact the connection pipe 21, so that after the transmission pipe 10 is pulled out later, the medicament inside the storage pool 2 will not flow out from the connection pipe 21 without restriction;

[0051] Specifically, at the lower end of the optical detection module, there is a connection block 23. The connection block 23 has the same weight as the storage pool 2. On both sides between the connection block 23 and the storage pool 2, there are first transmission frames 1. Both first transmission frames 1 are in threaded cooperation with the outer walls of the connection block 23 and the storage pool 2. The first transmission frames 1 can synchronously drive the connection block 23 and the storage pool 2 to rotate and adjust the position through the transmission of the transmission group. Among them, the connection block 23 is mainly used to offset the weight of the storage pool 2 when connected to the first transmission frame 1, so that the first transmission frame 1 can be stably installed in the middle position inside the drug screening and detection device;

[0052] Refer to Figure 1 and Figure 3The transmission group will transmit the bidirectional threaded rod 8 and the first transmission frame 1. A motor is provided on one side of the transmission block 7 in the transmission group. The output of the motor can make the bidirectional threaded rod 8 and the first transmission frame 1 connected by the transmission group rotate synchronously. The rotation of the bidirectional threaded rod 8 will drive the second transmission frame 9 to move relatively, and the rotation of the first transmission frame 1 can adjust the position of the storage tank 2.

[0053] like Figure 6 As shown, the motor drive connected to the transmission block 7 at one end of the bidirectional threaded rod 8 can synchronously drive the transmission structure inside the hair follicle drug screening and detection device to rotate and transmit synchronously. The synchronous transmission can avoid the need to manually press the switch at each position independently, and avoid the need to manually press the switch. The internal transmission structure needs to avoid collision and jamming during transmission. The synchronous transmission can achieve efficient detection of the medicine inside the storage tank 2. Similarly, the synchronous transmission can also adjust the position and direction of the storage tank 2 inside the hair follicle drug screening and detection device. The adjustment of the direction also facilitates the adjustable spray assembly 4 to spray pure water and perform direct cleaning.

[0054] Specifically in this embodiment, Figure 3 and Figure 4 As shown, the transmission group includes a transmission rod 5, a gear 6, a transmission block 7, a tooth groove 18 and a synchronous belt 24 for connecting the gear 6 and the transmission rod 5. The outer part of the tooth groove 18 is evenly distributed in the half area outside the transmission block 7. The tooth groove 18 is meshed and connected with the gear 6. After the tooth groove 18 rotates with the transmission block 7 and contacts the gear 6, it will drive the gear 6 to rotate, wherein the transmission block 7, the gear 6 and the transmission rod 5 are all rotatably connected with the housing of the hair follicle drug screening and detection device;

[0055] In addition, when the storage tank 2 is located at the upper end of the optical detection module and the connecting block 23 is located at the lower end of the optical detection module, the tooth groove 18 distribution area is located on one side of the upper end of the gear 6, so that the transmission block 7 will not contact the tooth groove 18 first when rotating counterclockwise, and the tooth groove 18 can only contact the gear 6 after the transmission block 7 rotates for a certain period of time, so that the second transmission frame 9 drives the transmission tube 10 to be pulled out from the position of the connecting tube 21, and then the storage tank 2 rotates;

[0056] The AI-based hair follicle drug screening and detection device of this embodiment stores the drugs in the storage pool 2 after detection through the lower storage frame 3 at the lower end of the first transmission frame 1. The storage pool 2 will flip over when driven by the transmission group, and the flipping of the storage pool 2 will actively dump the medicine inside, so that the medicine can fall into the lower storage frame 3, which is convenient for cleaning the lower storage frame 3. During the cleaning process of the storage pool 2, the adjustable spray assembly 4 arranged in an array at the middle position of the upper end of the lower storage frame 3 sprays pure water for cleaning;

[0057] The pure water required for cleaning and the chemicals discharged from the storage tank 2 will directly flow into the inner part of the lower storage frame 3. The waste water and chemicals are collected uniformly by the lower storage frame 3. Uniform collection can improve the treatment effect of chemicals and waste, facilitate subsequent unified direct discharge, and prevent the chemicals after detection and the cleaned pure water from affecting the subsequent AI screening and detection of chemicals.

[0058] After the pure water is extracted and contacts the connecting block 23, the wet storage tank 2 will affect the accuracy of subsequent chemical detection. As Figure 2 shown, the fixed plate 11 at the upper end of one side of the lower storage frame 3 will slide horizontally and move to the lower end of the storage tank 2 after flipping. One end of the fixed plate 11 is provided with a hot air blower 12. The exhaust holes 16 for exhausting gas are arrayed on the upper end of the fixed plate 11. Among them, the exhaust holes 16 are hermetically connected to the hot air blower 12. After the hot air blower 12 is started, gas can enter the storage tank 2, so that the storage tank 2 can be restored to dryness after cleaning.

[0059] The arrayed exhaust holes 16 are all connected to the hot air blower 12. The dry hot air extracted and heated by the hot air blower 12 will be shunted by the exhaust holes 16. The arrayed exhaust holes 16 can make the heated dry gas evenly distributed inside the storage tank 2, which is convenient for comprehensively drying the inside of the cleaned storage tank 2 and facilitating the efficient reuse of the storage tank 2 after cleaning.

[0060] Embodiment 2

[0061] To facilitate the discharge of the chemicals inside the storage tank 2 and prevent the chemicals from being discharged and blocking the upper end of the adjustable spray component 4, as Figure 5 shown, drain holes 14 are provided on both sides of the front end of the storage tank 2, and the drain holes 14 penetrate and extend to both the inside and outside of the storage tank 2. Through the penetrating drain holes 14, the chemicals can be discharged when the storage tank 2 is flipped, preventing the chemicals from falling on the drainage position of the adjustable spray component 4.

[0062] Among them, the liquid chemicals transmitted at the position of the transmission pipe 10 will converge inside the storage tank 2, and the horizontal plane of the chemicals will not be higher than the drain holes 14.

[0063] Embodiment 3

[0064] A one-way threaded rod 13 is penetrated through the lower end of the outer wall of the hot air blower 12, and the outer part of the one-way threaded rod 13 is in threaded cooperation with the outer wall of the hot air blower 12. After the one-way threaded rod 13 is driven and rotated, it can drive the fixed plate 11 and the hot air blower 12 to move horizontally, so that the fixed plate 11 dries the storage tank 2 after cleaning the storage tank 2.

[0065] Embodiment 4

[0066] The adjustable spray assembly 4 includes: an outer ring bracket 25 and an inner ring bracket 26. The outer ring bracket 25 and the inner ring bracket 26 are connected by a number of groups of connecting brackets 28. A number of groups of inner ring fan blades 27 are installed inside the inner ring bracket 26, and a number of groups of inner ring fan blades 27 are installed between the outer ring bracket 25 and the inner ring bracket 26. The drive motor 31 is fixedly arranged on the outer wall of the outer ring bracket 25. A drive gear 32 is fixedly sleeved on the output shaft of the drive motor 31. An annular drive member 33 is movably sleeved on the outer wall of the outer ring bracket 25, and the annular drive member 33 is connected to the outer ring bracket 25 by a thread. A number of groups of meshing teeth 34 are arranged on the outer wall of the annular drive member 33, and the drive gear 32 meshes with the number of groups of meshing teeth 34. A number of groups of supporting members 38 are fixedly arranged around the outer wall of the outer ring bracket 25, and a same first rotating bearing 35 is installed in each group of supporting members 38. The first rotating connecting member 37 is connected to the outer ring bracket 25 through the first rotating bearing 35, and one end of the first rotating connecting member 37 extends out of the first rotating bearing 35 and is fixedly connected to the drive connecting rod 36. The other end of the first rotating connecting member 37 is fixedly connected to the outer ring fan blade 29. The end of the drive connecting rod 36 away from the first rotating bearing 35 is movably connected to the outer wall of the annular drive member 33. A number of groups of supporting grooves 41 and through holes 42 are formed in the inner ring bracket 26, and each group of supporting grooves 41 and through holes 42 are coaxially arranged. A same second rotating bearing 40 is installed in each group of supporting grooves 41. The second rotating connecting member 39 is movably connected to the inner ring bracket 26 through the second rotating bearing 40. One end of the second rotating connecting member 39 extends out of the second rotating bearing 40 and is fixedly connected to the outer ring fan blade 29. The other end of the second rotating connecting member 39 passes through the through hole 42 and is fixedly connected to the inner ring fan blade 27. The outer ring fan blade 29 and the inner ring fan blade 27 located on the same axis are arranged perpendicular to each other.

[0067] Specifically, as Figure 7 shown in, a housing is sleeved on the outer wall of the outer ring bracket 25. This housing can protect the drive motor 31 and all the components installed on the outer wall of the outer ring bracket 25 from being damaged.

[0068] The working principle and beneficial effects of the above technical solution are as follows: To achieve all-round cleaning and ensure thorough cleaning inside the storage tank 2, during cleaning, the driving motor 31 is started to drive the annular driving member 33 to rotate. Since the annular driving member 33 is connected to the outer ring bracket 25 through threads, the annular driving member 33 rises and falls while rotating around the outer wall of the outer ring bracket 25. At this time, several groups of driving connecting rods 36 are deflected under the drive of the annular driving member 33, and then the outer ring fan blades 29 are driven by the annular driving member 33 to rotate. By controlling the deflection angles of several groups of outer ring fan blades 29, the area of the channel between the outer ring bracket 25 and the inner ring bracket 26 through which water flows can be changed. While changing the impact force of the water flow on the inner wall of the storage tank 2, the impact angle of the water flow can also be changed, so as to achieve all-round cleaning of the inner wall of the storage tank 2. And because the outer ring fan blades 29 and the inner ring fan blades 27 located on the same axis are arranged perpendicular to each other, when the outer ring fan blades 29 close the channel between the outer ring bracket 25 and the inner ring bracket 26, the channel of the inner ring bracket 26 is in an open state, so that the water flow can be concentrated and sprayed for cleaning. When the outer ring fan blades 29 open the channel between the outer ring bracket 25 and the inner ring bracket 26, the channel of the inner ring bracket 26 is in a closed state, so that the water flow can be dispersed into water mist or a large range of water flow for flushing, and it can also be adjusted to a semi-open and semi-closed mode for use, so as to adapt to the flow characteristics of different agents, for the detection of different types of agents, and improve the cleaning effect on complex agents or high-viscosity substances.

[0069] Embodiment 5

[0070] It further includes:

[0071] A tension sensor is arranged on the synchronous belt 24 for monitoring the tension level of the synchronous belt 24 during use;

[0072] A laser alignment sensor is arranged on the inner wall of the detection device housing and on the same axis as the synchronous belt 24 for monitoring the offset of the synchronous belt 24 during use;

[0073] A temperature sensor is arranged inside the detection device housing for monitoring the ambient temperature of the synchronous belt 24 during operation;

[0074] A rotational speed sensor one is arranged on the transmission rod 5 for monitoring the rotational speed of the transmission rod 5;

[0075] A rotational speed sensor two is arranged on the transmission block 7 for monitoring the rotational speed of the transmission block 7;

[0076] A timer is arranged on the outer surface of the detection device for monitoring the usage duration of the detection device;

[0077] An alarm, the alarm is provided on the outer surface of the detection device;

[0078] A controller, the controller is provided on the outer surface of the housing of the detection device, the controller is electrically connected to a tension sensor, a laser alignment sensor, a temperature sensor, a first rotational speed sensor, a second rotational speed sensor, a timer and an alarm respectively, and the controller controls the alarm to work based on the tension sensor, the laser alignment sensor, the temperature sensor, the first rotational speed sensor, the second rotational speed sensor, and the timer, including:

[0079] Step 1: The controller calculates the strain state coefficient of the synchronous belt 24 during use based on the tension sensor, the laser alignment sensor, the timer, the first rotational speed sensor, the second rotational speed sensor and formula (1):

[0080]

[0081] Wherein, X is the strain state coefficient of the synchronous belt 24 during use, F1 is the detection value of the tension sensor, F2 is the maximum tension that the synchronous belt 24 can withstand preset, n1 is the detection value of the first rotational speed sensor, n2 is the detection value of the second rotational speed sensor, L1 is the detection value of the laser alignment sensor, R1 is the radius of the transmission rod 5, R2 is the radius of the motor output shaft that drives the transmission block 7 to rotate, s is the detection value of the timer, μ1 is the friction coefficient of the synchronous belt 24, θ is the Poisson's ratio of the material of the synchronous belt 24, S1 is the contact area between the synchronous belt 24 and the transmission rod 5, E is the shear modulus of the synchronous belt 24, and ln is the natural logarithm with e as the base;

[0082] Step 2: Based on Step 1, the controller calculates the life index of the synchronous belt 24 based on the temperature sensor and formula (2):

[0083]

[0084] Wherein, Y is the life index of the synchronous belt 24, is the maximum wear amount preset for the synchronous belt 24, T1 is the detection value of the temperature sensor, T2 is the current ambient temperature, K is the product of the accuracies of the tension sensor, the laser alignment sensor, the temperature sensor, the first rotational speed sensor, the second rotational speed sensor, and the timer (the value is greater than 0 and less than 1, and can be related to the used duration of the sensor), Δ1 is the preset damage coefficient of the synchronous belt 24 (the value is greater than 0 and less than 1, and can be related to the used duration of the synchronous belt 24 and the influence of the use environment on the synchronous belt 24), and e is the natural constant, with a value of 2.72;

[0085] Step 3: The controller compares the life index of the synchronous belt 24 calculated in Step 2 with a preset life index. When the life index of the synchronous belt 24 calculated in Step 2 is less than the preset life index, the controller controls the alarm to give an alarm prompt.

[0086] The working principle and beneficial effects of the above technical solution are as follows: Since excessive tension will increase friction and burden, resulting in premature wear of the belt and wheels, while too low tension will cause the belt to slip and reduce transmission efficiency, and poor alignment of the belt pulley will cause the belt to run unevenly, resulting in side wear or excessive wear. Environmental factors such as temperature, humidity, and dust will all affect the life of the belt. Most importantly, high temperature will accelerate the aging of rubber, and different belt materials (such as rubber, polyurethane) and types (such as V-belts, synchronous belts) have different durability and application ranges. Based on this, the above solution can monitor the tension level of the synchronous belt 24 during use through a tension sensor, a laser alignment sensor to monitor the offset of the synchronous belt 24 during use, and a temperature sensor to monitor the ambient temperature of the synchronous belt 24 during operation. Then, the strain state coefficient of the synchronous belt 24 during use is calculated through Formula (1), and the life index of the synchronous belt 24 is calculated through Formula (2). The controller can control the alarm to work according to the life index of the synchronous belt 24. When the life index of the synchronous belt 24 calculated in Step 2 is less than the preset life index (0.85), the controller controls the alarm to give an alarm prompt, and the operator replaces the synchronous belt 24 in time according to the alarm, thereby improving the safety of the equipment.

[0087] Embodiment 6

[0088] To enable the optical detection module to continuously face upward, as Figure 1 shown, both sides of the outer wall of the optical detection module are rotatably connected to the inside of the first transmission frame 1 through a connecting shaft 22;

[0089] Specifically, a counterweight is suspended at the lower end of the outer wall of the optical detection module. By suspending the counterweight, the optical detection module will not be affected and will continuously face upward after the first transmission frame 1 rotates.

[0090] Working principle: When using the device to screen hair follicle drugs, through AI calculation, a batch of the most likely drugs are sequentially put into the internal of the screening and detection device. The pump connected to one end of the transfer pipe 10 extracts the drugs and transports them to the inside of the storage pool 2 through the transfer pipe 10. The optical detection module at the lower end of the storage pool 2 is started, and the optical detection module detects the data of the medicinal material solution inside the storage pool 2. The detected data is calculated by matching with AI and curve fitting is carried out to judge the drug effectiveness, thereby realizing a single screening. The motor will first drive the transmission block 7 to rotate. The rotation of the transmission block 7 will directly drive the bidirectional threaded rod 8 to rotate. When the bidirectional threaded rod 8 rotates, a relative movement will be generated between the bidirectional threaded rod 8 and the two second transmission frames 9 at the same time. After the second transmission frame 9 is restricted by the housing of the screening and detection device, the second transmission frame 9 drives the transfer pipe 10 connected to the lower end to be pulled out from the connection pipe 21 positions on both sides of the storage pool 2. During the process that the transmission block 7 drives the bidirectional threaded rod 8 to rotate, the transmission block 7 will drive the tooth groove 18 to rotate counterclockwise and move towards the gear 6. After the transfer pipe 10 is pulled out, the tooth groove 18 will contact the gear 6 and generate a meshing connection. The counterclockwise rotation of the transmission block 7 will drive the gear 6 to rotate clockwise. The rotation of the gear 6 will be transmitted through the synchronous belt 24. The gear 6 will drive the transmission rod 5 to rotate clockwise. The rotation of the transmission rod 5 will drive the storage pool 2 to rotate slowly clockwise through the first transmission frame 1. During the rotation process, the storage pool 2 will drive the internal medicine to pour, so that the medicine can be discharged from the liquid discharge hole 14 position. After the storage pool 2 rotates, the storage pool 2 is aligned with the adjustable spraying component 4. The pump extracts pure water and discharges it from the position of the adjustable spraying component 4. The discharged liquid will actively clean the storage pool 2. After cleaning the storage pool 2, the rotation of the unidirectional threaded rod 13 can drive the fixed disk 11 and the hot air blower 12 to move towards the storage pool 2. The hot air blower 12 is started. The hot air blower 12 extracts the external gas, heats it and discharges it from the exhaust hole 16 position. The hot air will dry the cleaned storage pool 2. When the transmission block 7 rotates clockwise, the storage pool 2 will be driven by the tooth groove 18 to flip between the two second transmission frames 9 first. As the transmission block 7 continues to rotate, the second transmission frame 9 will drive the transfer pipe 10 to be repeatedly inserted into the two sides outside the storage pool 2.

[0091] It should be noted that in this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device.

[0092] Although embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention.

Claims

1. An AI-based follicular drug screening and detection device, comprising a storage pool (2), an optical detection module, and transfer tubes (10) on both sides of the storage pool (2), characterized in that, A bidirectional threaded rod (8) is provided at the upper end of the storage tank (2). On both sides of the outside of the optical detection module, a first transmission frame (1) is provided. After the transmission pipe (10) is moved away from the storage tank (2) by the transmission group, the first transmission frame (1) rotates again. The transmission group includes a transmission rod (5), a gear (6), a transmission block (7), a tooth groove (18), and a synchronous belt (24) for connecting the gear (6) and the transmission rod (5). Half of the circle of the transmission block (7) is provided with a tooth groove (18), and the tooth groove (18) is meshed and connected with the gear (6). The transmission block (7) is welded to one side of the bidirectional threaded rod (8). The transmission rod (5) is welded to one side of the first transmission frame (1). When the storage tank (2) is located above the optical detection module, the tooth groove (18) outside the transmission block (7) is located on one side above the gear (6). When the transmission block (7) rotates and the tooth groove (18) contacts the gear (6), the gear (6) is driven to rotate clockwise. The bidirectional threaded rod (8) rotates and drives the transmission pipe (10) to move horizontally through the threaded fit with the second transmission frame (9). Both sides of the storage tank (2) are hermetically connected to the transmission pipe (10) through a connecting pipe (21). A connecting block (23) with the same weight as the storage tank (2) is provided at the lower end of the optical detection module. The first transmission frame (1) is fixed to the outer walls of the storage tank (2) and the connecting block (23) respectively by bolts. When the storage tank (2) is located above the optical detection module and the connecting block (23) is located below the optical detection module, the distribution area of the tooth groove (18) is located on one side above the gear (6), so that when the transmission block (7) rotates counterclockwise, it will not contact the tooth groove (18) first, and the tooth groove (18) can contact the gear (6) only after the transmission block (7) rotates for a certain time. After the second transmission frame (9) drives the transmission pipe (10) to be pulled out from the position of the connecting pipe (21), the storage tank (2) rotates.

2. The AI-based hair follicle drug screening and detection device according to claim 1, wherein: A lower storage frame (3) is provided at the lower end of the connecting block (23). An adjustable spraying component (4) is provided on the lower storage frame (3) facing the storage tank (2). A hot air blower (12) is provided on one side of the upper end of the adjustable spraying component (4).

3. The AI-based hair follicle drug screening and detection device according to claim 2, wherein: A fixed disk (11) with exhaust holes (16) is provided on the side of the hot air blower (12) facing the adjustable spraying component (4). The exhaust holes (16) face the storage tank (2) and are hermetically connected to the hot air blower (12). After being driven by the transmission group, the storage tank (2) will be flipped to the upper end of the fixed disk (11).

4. The AI-based hair follicle drug screening and detection device according to claim 3, characterized in that: The hot air blower (12) is driven to adjust the horizontal position through a unidirectional threaded rod (13).

5. The AI-based hair follicle drug screening and detection device according to claim 4, wherein: Drain holes (14) are provided on both sides of the front end of the storage tank (2). The liquid level of the medicine transmitted into the storage tank (2) by the transmission pipe (10) is not higher than the drain holes (14).

6. The AI-based hair follicle drug screening and detection device according to claim 5, wherein: The adjustable spray assembly (4) includes: an outer ring bracket (25) and an inner ring bracket (26). The outer ring bracket (25) and the inner ring bracket (26) are connected by several groups of connecting brackets (28). Several groups of inner ring fan blades (27) are installed inside the inner ring bracket (26), and several groups of inner ring fan blades (27) are installed between the outer ring bracket (25) and the inner ring bracket (26). The driving motor (31) is fixedly arranged on the outer wall of the outer ring bracket (25). A driving gear (32) is fixedly sleeved on the output shaft of the driving motor (31). The annular driving member (33) is movably sleeved on the outer wall of the outer ring bracket (25), and the annular driving member (33) is connected to the outer ring bracket (25) by a thread. Several groups of meshing teeth (34) are arranged on the outer wall of the annular driving member (33), and the driving gear (32) meshes with several groups of meshing teeth (34). Several groups of supporting members (38) are fixedly arranged around the outer wall of the outer ring bracket (25), and a same first rotating bearing (35) is installed in each group of supporting members (38). The first rotating connecting member (37) is connected to the outer ring bracket (25) through the first rotating bearing (35), and one end of the first rotating connecting member (37) extends out of the first rotating bearing (35) and is fixedly connected to the driving link (36). The other end of the first rotating connecting member (37) is fixedly connected to the outer ring fan blade (29). The end of the driving link (36) far from the first rotating bearing (35) is movably connected to the outer wall of the annular driving member (33). Several groups of supporting grooves (41) and through holes (42) are formed on the inner ring bracket (26), and each group of supporting grooves (41) and through holes (42) are coaxially arranged. A same second rotating bearing (40) is installed in each group of supporting grooves (41). The second rotating connecting member (39) is movably connected to the inner ring bracket (26) through the second rotating bearing (40). One end of the second rotating connecting member (39) extends out of the second rotating bearing (40) and is fixedly connected to the outer ring fan blade (29). The other end of the second rotating connecting member (39) passes through the through hole (42) and is fixedly connected to the inner ring fan blade (27). The outer ring fan blade (29) and the inner ring fan blade (27) located on the same axis are perpendicularly arranged.

7. The AI-based hair follicle drug screening and detection device according to claim 1, characterized in that: It further includes: a tension sensor, arranged on the synchronous belt (24) for monitoring the tension level of the synchronous belt (24) during use; a laser alignment sensor, arranged on the inner wall of the detection device housing and on the same axis as the synchronous belt (24) for monitoring the offset of the synchronous belt (24) during use; a temperature sensor, arranged inside the detection device housing for monitoring the ambient temperature where the synchronous belt (24) is located during operation; a first rotational speed sensor, arranged on the transmission rod (5) for monitoring the rotational speed of the transmission rod (5); a second rotational speed sensor, arranged on the transmission block (7) for monitoring the rotational speed of the transmission block (7); a timer, arranged on the outer surface of the detection device for monitoring the usage duration of the detection device; an alarm, the alarm is arranged on the outer surface of the detection device; A controller, the controller is arranged on the outer surface of the detection device housing, the controller is electrically connected to a tension sensor, a laser alignment sensor, a temperature sensor, a first rotational speed sensor, a second rotational speed sensor, a timer and an alarm respectively, and the controller controls the operation of the alarm based on the tension sensor, the laser alignment sensor, the temperature sensor, the first rotational speed sensor, the second rotational speed sensor and the timer, including: Step 1: The controller calculates the strain state coefficient of the synchronous belt (24) during use based on the tension sensor, the laser alignment sensor, the timer, the first rotational speed sensor, the second rotational speed sensor and formula (1): (1) Among them, is the strain state coefficient of the synchronous belt (24) during use, is the detected value of the tension sensor, is the preset maximum tension that the synchronous belt (24) can withstand, is the detected value of the first rotational speed sensor, is the detected value of the second rotational speed sensor, is the detected value of the laser alignment sensor, is the radius of the transmission rod (5), is the radius of the motor output shaft that drives the transmission block (7) to rotate, and s is the detected value of the timer, is the friction coefficient of the synchronous belt (24), is the Poisson's ratio of the material of the synchronous belt (24), is the contact area between the synchronous belt (24) and the transmission rod (5), and E is the shear modulus of the synchronous belt (24), is the natural logarithm with e as the base; Step 2: Based on Step 1, the controller calculates the life index of the synchronous belt (24) based on the temperature sensor and formula (2): (2) wherein, is the life index of the synchronous belt (24), is the maximum wear amount of the preset synchronous belt (24), is the detected value of the temperature sensor, is the current ambient temperature, K is the product of the accuracy of the tension sensor, laser alignment sensor, temperature sensor, speed sensor 1, speed sensor 2, and timer, is the preset damage coefficient of the synchronous belt (24), is the natural constant, with a value of 2.72; Step 3: The controller compares the life index of the synchronous belt (24) calculated in Step 2 with a preset life index. When the life index of the synchronous belt (24) calculated in Step 2 is less than the preset life index, the controller controls the alarm to give an alarm prompt.

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