An anti-aging composition and its application in skin care field

Abstract

The present invention relates to the technical field of skin care products, and specifically to an anti-aging composition and its application in the field of skin care. The present invention provides an anti-aging composition, which comprises the following components by mass: 0.01 to 2 parts of ergothioneine, 5 to 30 parts of plant extracts and 2 to 5 parts of a second antioxidant component, wherein the second antioxidant component is any one of asiaticoside, resveratrol, glabridin, glutathione and bosaicin, and the plant extract is any one or more of licorice (GLYCYRRHIZA URALENSIS) extract, forsythia (FORSYTHIA SUSPENSA) extract, viola mandshurica (VIOLA MANDSHURICA) flower extract, chuanxiong (LIGUSTICUM CHUANXIONG) extract and cynanchum atratum (CYNANCHUM ATRATUM) extract. The anti-aging composition is compounded with ergothioneine and a second antioxidant, and then an effective plant extract is added, so that the components of the anti-aging composition can reduce the overall raw material cost of the skin care product through good synergy and maintain a good anti-aging effect.

Description

Technical Field

[0001] The present invention relates to the technical field of skin care products, and in particular to an anti-aging composition and its application in the field of skin care. Background Art

[0002] As an important organ of the human body, the skin is responsible for many important physiological processes, such as protection against environmental and mechanical damage, perception of stimuli, temperature regulation, and immune monitoring. However, with age, the skin's morphology and physiological functions gradually degenerate. Anti-aging skin products have always been a hot topic of research in the cosmetics industry.

[0003] At present, the antioxidants widely used in the cosmetics industry include vitamin C, vitamin E, coenzyme Q10, glutathione, etc. They protect the skin from damage by replacing free radicals, thereby achieving the effect of anti-aging, but these antioxidants cannot enter the mitochondria and inhibit the production of ROS from the root. Ergothioneine (EGT) is a natural small molecule histidine thiourea derivative that exists in microbial cells and animals and plants. EGT has multiple biological functions such as anti-oxidation, anti-inflammatory, and immunomodulation, and has good application prospects in the fields of food, medicine, and cosmetics.

[0004] Existing studies have shown that EGT has protective and preventive effects on some diseases related to aging. Telomere shortening is associated with aging and a variety of age-related diseases, and oxidative stress is usually one of the main causes of telomere shortening. Under oxidative stress conditions, EGT shows its beneficial anti-aging effects by reducing the telomere shortening rate and maintaining telomere length. Compared with other thiol compounds such as glutathione, EGT can inactivate singlet oxygen at a higher rate. In 2014, the State Food and Drug Administration has included ergothioneine in the catalog of used cosmetic raw materials. However, due to the barriers in production technology of ergothioneine, its market price has remained high, limiting its application in skin care products. Therefore, there are very few skin care products on the market that contain ergothioneine, or although ergothioneine components are added, the amount added is small and the anti-aging effect is poor.

[0005] To solve the above problems, the prior art has made many explorations to this. On the one hand, the cost of thioneine can be reduced by solving the technical problems in thioneine production. For example, the Chinese invention patent with document number CN115322912B discloses a high-yield strain of thioneine and a screening method and application thereof, to improve thioneine yield; the Chinese invention patent with document number CN114854659B discloses a production process of thioneine and an application thereof, the invention prepares chassis cells by gene editing to Escherichia coli, expresses thioneine synthesis gene clusters in chassis cells, and successfully constructs thioneine production strains, and the industrial production cost of thioneine can be reduced by using the strain. On the other hand, the amount of ergothioneine added is reduced and the overall use effect of the skin care products is ensured by combining the components of the skin care products in a reasonable manner and utilizing the synergistic effect between the components. For example, the Chinese invention patent with the document number CN 118021644A proposes a stable synergistic enhancement composition based on asiaticoside and ergothioneine, which efficiently inhibits the photodecomposition and high-temperature instability of ergothioneine through asiaticoside, and synergistically enhances the antioxidant and skin repair effects of ergothioneine. This type of technical solution can reduce the amount of ergothioneine added in skin care products while ensuring its anti-aging effect, and is also a current research hotspot for ergothioneine in the field of skin care product applications. Summary of the invention

[0006] The present invention aims to provide an anti-aging composition and application thereof in the field of skin care, so as to solve the technical problems of high cost of raw materials of skin care products and poor anti-aging effect of skin care products caused by high cost of ergothioneine in the prior art.

[0007] In order to achieve the above object, the present invention adopts the following technical scheme:

[0008] In a first aspect, the present invention provides an anti-aging composition, which comprises the following components: 0.01 to 2 parts of ergothioneine, 5 to 30 parts of plant extracts, and 2 to 5 parts of a second antioxidant component, wherein the second antioxidant component is any one of asiatica glycoside, resveratrol, glycyrrhizin, glutathione, and bosacene.

[0009] Preferably, the second antioxidant component is a mixture of asiaticoside and glutathione, and the mass ratio of asiaticoside to glutathione is (1-2):(2-5), and most preferably 1:4.

[0010] Furthermore, the plant extract is any one or more of a Glycyrrhiza uralensis extract, a Forsythia suspensa extract, a Viola mandshurica flower extract, a Ligusticum chuanxiong extract, and a Cynanchum atratum extract.

[0011] Preferably, the plant extract is a combination of a VIOLA MANDSHURICA flower extract and a CYNANCHUM ATRATUM extract.

[0012] Further preferably, the plant extract is a combination of a VIOLA MANDSHURICA flower extract and a CYNANCHUM ATRATUM extract, and the mass ratio of the VIOLA MANDSHURICA flower extract to the CYNANCHUM ATRATUM extract is 1:1-7, and most preferably, the mass ratio of the two is 1:1.

[0013] In a second aspect, the present invention further provides a use of the anti-aging composition described in the first aspect in skin care products.

[0014] Furthermore, the skin care product also includes a solvent, and the solvent is any one of water and oil, or the solvent is a mixture of water and oil.

[0015] Exemplarily, the solvent may be a mixture of water and oil, and the oil is selected from any one or more of MICHELIA ALBA flower oil, CAMELLIA SINENSIS seed oil, ROSA RUGOSA flower oil, ROSA RUGOSA fruit oil, and the like.

[0016] Furthermore, the skin care product also includes any one or more of an emulsifier, a preservative, a fragrance, a moisturizer, a pH regulator, a thickener, and a colorant.

[0017] Furthermore, the skin care product is any one of solid, liquid or semi-solid.

[0018] Furthermore, the skin care product may also include other functional components.

[0019] In a third aspect, the present invention further provides a method for preparing the aforementioned skin care product, wherein the skin care product is composed of the following components in parts by weight:

[0020] 70 parts of water, 30 parts of Michelia Alba flower oil, 0.1 parts of ergothioneine, 5 parts of VIOLAMANDSHURICA flower extract, 5 parts of CYNANCHUM ATRATUM extract, 1 part of Centella asiatica, 4 parts of glutathione, 5 parts of Ceteareth-20.

[0021] Exemplarily, the preparation method comprises the steps of:

[0022] S1: Add VIOLA MANDSHURICA flower extract, CYNANCHUM ATRATUM extract, glutathione, asiaticoside, and ergothioneine into water (40-50°C), and stir to evenly disperse them; add emulsifier ceteareth-20 into water, heat (70-80°C) and maintain magnetic stirring until the emulsifier is completely dissolved in water to form a uniform aqueous phase;

[0023] S2: Heat the Michelia Alba flower oil to 70-80°C, and slowly add the oil phase into the water phase, maintaining the stirring speed at about 400-800 rpm, and continue stirring for 10-15 minutes to fully emulsify the oil phase in the water phase. Finally, use a homogenizer to homogenize to obtain a skin care lotion.

[0024] In summary, the beneficial effects of this technical solution are summarized as follows:

[0025] The components of an anti-aging composition provided by the present invention have obvious synergistic effects. Specifically, the anti-aging composition contains ergothioneine, plant extracts and a specific second antioxidant component (such as asiaticoside, glutathione, etc.), wherein ergothioneine has antioxidant properties and can help resist the damage of free radicals to skin cells; plant extracts (such as northeastern violet flower extracts, white lily extracts, etc.) may be rich in a variety of biologically active ingredients, with antioxidant, anti-inflammatory and other effects, in addition, the second antioxidant component can also play an antioxidant role. These components work synergistically to more effectively remove free radicals and reduce the signs of aging caused by oxidative stress reactions on the skin, such as wrinkles, sagging, etc., and in the anti-aging composition, due to the synergistic effect between the components, it has been proved by cell experiments that it has obvious synergistic effects in anti-aging, thus, at a lower amount of ergothioneine added, the skin care products can also fully exert their anti-aging effects. DETAILED DESCRIPTION

[0026] The following examples are only used to more clearly illustrate the technical scheme of the present invention, and are therefore only used as examples, and cannot be used to limit the scope of the present invention. For those skilled in the art, any equivalent modifications and substitutions to the embodiments described below are also within the scope of the present invention. Therefore, the equalization transformations and modifications made without departing from the spirit and scope of the present invention should all be included in the scope of the present invention. Those who do not specify specific conditions in the embodiments are carried out according to normal conditions or the conditions recommended by the manufacturer. All reagents or instruments that do not specify manufacturers are conventional products that can be purchased commercially.

[0027] In order to better illustrate the present invention, numerous specific details are provided in the following specific embodiments. It should be understood by those skilled in the art that the present invention can be implemented without certain specific details. In other embodiments, methods, means, equipment and steps well known to those skilled in the art are not described in detail in order to highlight the subject matter of the present invention.

[0028] Unless otherwise defined, all technical and scientific terms used herein have the same meanings as those commonly understood by those skilled in the art. Unless otherwise specified, the units used in this specification are all international standard units, and the numerical values ​​and numerical ranges appearing in the present invention should be understood to include the inevitable errors in industrial production.

[0029] Example 1

[0030] This embodiment provides a combination of 6 anti-aging compositions, specifically:

[0031] An anti-aging composition 1, comprising the following components in parts by weight: 0.1 parts of ergothioneine, 1 part of asiatica glycoside and 4 parts of glutathione, wherein the anti-aging composition 1 does not contain a plant extract component;

[0032] Anti-aging composition 2, comprising the following components in parts by weight: 0.1 parts of ergothioneine, 10 parts of liquorice extract, 1 part of asiatica glycoside and 4 parts of glutathione;

[0033] Anti-aging composition 3, comprising the following components in parts by weight: 0.1 parts of ergothioneine, 10 parts of Forsythia suspensa extract, 1 part of Centella asiatica glycoside and 4 parts of glutathione;

[0034] Anti-aging composition 4, comprising the following components in parts by weight: 0.1 parts of ergothioneine, 10 parts of VIOLAMANDSHURICA flower extract, 1 part of asiatica glycoside and 4 parts of glutathione;

[0035] The anti-aging composition 5 comprises the following components in parts by weight: 0.1 parts of ergothioneine, 10 parts of Ligusticum chuanxiong extract, 1 part of asiatica glycoside and 4 parts of glutathione;

[0036] Anti-aging composition 6, comprising the following components in parts by weight: 0.1 parts of ergothioneine, 10 parts of CYNANCHUMATRATUM extract, 1 part of asiatica glycoside and 4 parts of glutathione;

[0037] In the anti-aging compositions 1 to 6, the present inventors focused on exploring whether the addition of various plant extracts can effectively enhance the anti-aging effect of the combination of ergothioneine, asiatica glycoside and glutathione.

[0038] Test Example 1

[0039] This test example tests the efficacy of anti-aging compositions 1 to 6, including:

[0040] Free radical (DPPH) scavenging experiment

[0041] DPPH (1,1-diphenyl-2-trinitrophenylhydrazine) is a stable free radical. When antioxidants (such as anti-aging ingredients in skin care products) are present, the antioxidants can provide hydrogen atoms to pair with the single electron of the DPPH free radical, turning it into a stable molecule, thereby lightening the color of the solution. By detecting the change in absorbance of the solution at 517nm before and after the reaction, the ability of the antioxidant to scavenge DPPH free radicals can be calculated. The stronger the antioxidant's ability to scavenge DPPH free radicals, the lighter the solution color and the greater the decrease in absorbance. Therefore, DPPH scavenging rate is often used to evaluate the antioxidant effect of skin care products.

[0042] The experimental method used in this test case is as follows:

[0043] The specific experimental method is: prepare 0.1mM DPPH solution and measure the blank absorbance value; then take the anti-aging compositions 1 to 6 respectively and prepare them into 100μg / mL test solution, repeat the experiment three times for each test solution, take 0.5mL of the test solution and add it to 4.5mL DPPH solution, measure the absorbance value of each group after reacting for 20 minutes, calculate the free radical scavenging rate according to the measured absorbance value and the blank absorbance value, and the experimental results are shown in Table 1:

[0044] Table 1 DPPH scavenging rate test results of anti-aging compositions 1 to 6 (%)

[0045] Test Group DPPH removal rate (%) Anti-aging composition 1 64.25±3.12 Anti-aging composition 2 74.02±2.01 Anti-aging composition 3 71.91±3.12 Anti-aging composition 4 78.34±1.96 Anti-aging composition 5 75.48±2.08 Anti-aging composition 6 72.17±1.72

[0046] 1.2 Cellular reactive oxygen species (ROS) scavenging assay

[0047] The DCFH-DA fluorescent probe method is an experiment widely used in the skin care industry to detect the effect of the test substance on the scavenging of cellular reactive oxygen species (ROS). The principle is: DCFH-DA (dichlorofluorescein diacetate) itself does not have fluorescence, but can freely pass through the cell membrane. After entering the cell, DCFH-DA will be hydrolyzed into DCFH by the esterase in the cell. Since DCFH cannot pass through the cell membrane, it will accumulate in the cell, and the ROS in the cell can oxidize the non-fluorescent DCFH to generate fluorescent DCF, so the fluorescence intensity is proportional to the ROS level in the cell. Therefore, the level of ROS in the cell can be indirectly reflected by detecting the intensity of fluorescence.

[0048] The experimental method used in this test case is as follows:

[0049] (1) Cell preparation:

[0050] HaCaT cells in the logarithmic growth phase were digested with trypsin to prepare a cell suspension; 1×10 5 The density of cells / mL was inoculated in a 96-well plate;

[0051] (2) Administration:

[0052] The groups included a blank control group (no injury and no medication), a negative control group (injury but no medication), and an experimental group (injury and medication). The experimental groups were respectively prepared with anti-aging compositions 1 to 6 into 100 μg / mL test solutions for medication, with a medication volume of 120 uL. After medication, the cells were incubated in a 37°C, 5% CO2 incubator for 24 hours.

[0053] (3) Cell damage:

[0054] After the incubation, the oxidative damage model was established by referring to the hydrogen peroxide method in the "Cosmetic Firming and Anti-wrinkle-In Vitro Keratinocyte Reactive Oxygen Species (ROS) Inhibition Test Method";

[0055] (4) Probe loading:

[0056] The culture medium was discarded and the cells were washed with PBS. After washing, 100 uL of DCFH-DA working solution (concentration of 10 umol / L) was added to each well and incubated for 45 min. After the incubation was completed, the fluorescence intensity of each experimental group was measured and counted.

[0057] The experimental results are expressed as the relative values ​​of each experimental group and the blank control group. The experimental results are shown in Table 2;

[0058] Table 2 Results of the cell reactive oxygen species (ROS) scavenging test of anti-aging compositions 1 to 6 (n=3)

[0059] Fluorescence intensity (mean) Relative fluorescence intensity (%) ROS repair and clearance rate (%) Blank control group 19830.87 100.00 / Negative control group 46882.16 236.41 / Anti-aging composition 1 34309.39 173.01 26.82% Anti-aging composition 2 28344.26 142.93 39.54% Anti-aging composition 3 30454.27 153.57 35.04% Anti-aging composition 4 26845.05 135.37 42.74% Anti-aging composition 5 27350.74 137.92 41.66% Anti-aging composition 6 28046.80 141.43 40.18%

[0060] Among them, ROS repair clearance rate (%) = (1-fluorescence intensity of experimental group / fluorescence intensity of negative control group) * 100%;

[0061] It can be seen from this test example that the composition provided by the present invention (0.1 parts of ergothioneine, 1 part of asiaticoside and 4 parts of glutathione) has a good scavenging effect on cellular reactive oxygen species (ROS) (ROS repair clearance rate is 26.82%), and the addition of a single plant extract, including licorice (GLYCYRRHIZA URALENSIS) extract, forsythia (FORSYTHIA SUSPENSA) extract, northeast violet (VIOLA MANDSHURICA) flower extract, chuanxiong (LIGUSTICUM CHUANXIONG) extract, cynanchum atratum (CYNANCHUM ATRATUM) extract, etc., can further improve the antioxidant effect and anti-aging effect of the aforementioned composition (0.1 parts of ergothioneine, 1 part of asiaticoside and 4 parts of glutathione).

[0062] Example 2

[0063] This example further explores whether the combination of different plant extracts can play a synergistic role in the antioxidant and anti-aging effects of the anti-aging composition 1 on the basis of Example 1. The specific experimental design is as follows:

[0064] This embodiment provides 6 groups of anti-aging compositions, each of which comprises: 0.1 parts of ergothioneine, 1 part of asiatica glycoside, 4 parts of glutathione and 10 parts of plant extracts. The composition of the plant extracts in each anti-aging composition is shown in Table 3:

[0065] Table 3 Composition of plant extracts in each group of anti-aging compositions (mass fraction)

[0066] VIOLAMANDSHURICA FLOWER EXTRACT FORSYTHIASUSPENSA Extract Licorice Extract Ligusticum chuanxiong Extract CYNANCHUMATRATUM Extract Anti-aging composition 7 5 5 0 0 0 Anti-aging composition 8 5 0 5 0 0 Anti-aging composition 9 5 0 0 5 0 Anti-aging composition 10 5 0 0 0 5 Anti-aging composition 11 0 5 0 5 0 Anti-aging composition 12 0 0 0 5 5

[0067] Test Example 2

[0068] The efficacy test of the anti-aging compositions 7 to 12 includes:

[0069] 2.1 Free radical (DPPH) scavenging experiment

[0070] The free radical (DPPH) scavenging experiment was carried out according to 1.1. The experimental results are shown in Table 4:

[0071] Test Group DPPH removal rate (%) Anti-aging composition 7 82.09±2.35 Anti-aging composition 8 88.16±3.44 Anti-aging composition 9 92.84±3.01 Anti-aging composition 10 97.31±2.38 Anti-aging composition 11 89.14±2.39 Anti-aging composition 12 86.35±4.06

[0072] 2.2 Cellular reactive oxygen species (ROS) scavenging assay

[0073] Refer to 1.2 for the cell reactive oxygen species (ROS) scavenging test. The experimental results are shown in Table 5:

[0074] Table 5 Results of the scavenging test of reactive oxygen species (ROS) in cells of anti-aging compositions 7 to 12 (n=3)

[0075] Fluorescence intensity Relative fluorescence intensity (%) ROS repair and clearance rate (%) Blank control group 20340.59 100.00 / Negative control group 53941.95 272.01 / Anti-aging composition 7 28427.55 143.35 39.36% Anti-aging composition 8 27110.78 136.71 42.17% Anti-aging composition 9 24161.93 121.84 48.46% Anti-aging composition 10 17256.82 87.02 63.19% Anti-aging composition 11 24255.14 122.31 48.26% Anti-aging composition 12 25996.29 131.09 44.55%

[0076] It can be seen from the above test examples that among the various anti-aging compositions provided in Example 2, anti-aging composition 10 has the best antioxidant damage effect, and its ROS repair clearance rate can reach 63.19%, which is much higher than that of other groups, and is better than the effect of adding 10 parts of VIOLA MANDSHURICA flower extract (anti-aging composition 4 in Example 1) and 10 parts of CYNANCHUMATRATUM extract (anti-aging composition 6 in Example 1), which proves that there is an obvious synergistic effect between the VIOLAMANDSHURICA flower extract and the CYNANCHUM ATRATUM extract; and for the combination of other plant extracts, there is also a certain synergistic effect, but it is not obvious.

[0077] Example 3

[0078] This embodiment provides a skin care product, which is composed of the following raw materials in parts by weight:

[0079] 70 parts of water, 30 parts of Michelia Alba flower oil, 0.1 parts of ergothioneine, 5 parts of VIOLAMANDSHURICA flower extract, 5 parts of CYNANCHUM ATRATUM extract, 1 part of asiatica glycoside, 4 parts of glutathione, 5 parts of ceteareth-20, and 0.5 parts of tocopherol.

[0080] The preparation method is:

[0081] S1: Add VIOLA MANDSHURICA flower extract, CYNANCHUM ATRATUM extract, glutathione, asiaticoside, and ergothioneine to water (40-50°C), and stir to evenly disperse them; add emulsifier ceteareth-20 to water, heat (70-80°C) and maintain magnetic stirring until the emulsifier is completely dissolved in the water, then add tocopherol and continue stirring to form a uniform aqueous phase;

[0082] S2: Heat the Michelia Alba flower oil to 70-80°C, and slowly add the oil phase into the water phase, keeping the stirring speed at about 500 rpm, and continue stirring for 10-15 minutes to fully emulsify the oil phase in the water phase, then adjust the pH to about 6.0, and finally use a homogenizer to homogenize to obtain a skin care lotion.

[0083] Test Example 3

[0084] This test example tests the efficacy of the skin care product prepared in the above-mentioned Example 3. The test method and experimental results are as follows:

[0085] 3.1 Experimental group settings:

[0086] Example 3 was used as the test product 1. Based on the skin care product provided in Example 3, reference product 1 and reference product 2 were prepared in the same manner, wherein the raw materials of reference product 1 were as follows:

[0087] 70 parts of water, 30 parts of Michelia Alba flower oil, 0.1 parts of ergothioneine, 10 parts of violet flower extract, 1 part of asiatica glycoside, 4 parts of glutathione, 5 parts of ceteareth-20, and 0.5 parts of tocopherol.

[0088] The raw materials of reference substance 2 are as follows:

[0089] 70 parts of water, 30 parts of Michelia Alba flower oil, 0.1 parts of ergothioneine, 10 parts of CYNANCHUMATRATUM extract, 1 part of asiatica glycoside, 4 parts of glutathione, 5 parts of ceteareth-20, and 0.5 parts of tocopherol.

[0090] 3.2 Experimental methods:

[0091] Women aged 35-50 were selected as subjects and divided into three groups. The initial number of participants in each group was 20. The experimental period was 28 days. The test product 1, control product 1 and control product 2 provided by the present invention were used once every morning and evening after cleansing. Those who used the products 12 times or more per week were included in the statistics. The skin condition of each subject before and after use was tested. The test site was 2 cm below the eye. The experimental indicators included:

[0092] (01) TEWL (transepidermal water loss): TEWL is a key parameter for measuring skin barrier function. The stratum corneum, the outermost layer of the skin, mainly acts as a barrier to prevent excessive water loss and the invasion of harmful substances from the outside world. The lower the value, the less transepidermal water loss, indicating that the skin care product has a better effect on repairing the skin barrier;

[0093] (02) Stratum corneum moisture content (CU): The right amount of moisture in the stratum corneum is the key to maintaining skin elasticity and softness. Appropriate stratum corneum moisture content helps maintain the integrity of the skin barrier function and is one of the most commonly used indicators of skin barrier function. The higher the stratum corneum moisture content, the better the skin condition.

[0094] (03) Skin elasticity R2: The closer the value is to 1, the better the skin elasticity;

[0095] (04) SEw value for wrinkles. SEw value (Skin Elasticity wrinkle) comprehensively reflects the skin condition based on two important skin characteristics: skin elasticity and wrinkles. The smaller the SEw value, the better the skin condition.

[0096] The test results are shown in Table 6;

[0097] Table 6 Skin condition test results of each group of subjects before and after use

[0098]

[0099] The above experimental results show that test product 1 is significantly better than control product 1 and control product 2 in reducing skin TEWL value, increasing skin stratum corneum moisture content, improving skin elasticity and improving skin wrinkles, and the effect of control product 1 is also significantly better than control product 2.

[0100] The above experimental results show that there is an obvious synergistic effect between the flower extract of VIOLA MANDSHURICA and the extract of CYNANCHUMATRATUM.

[0101] The above is only an embodiment of the present invention, and the common knowledge such as the known specific technical solutions and / or characteristics in the solution is not described in detail here. It should be pointed out that for those skilled in the art, without departing from the technical solution of the present invention, several modifications and improvements can be made, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. An anti-aging composition, characterized in that: The invention comprises the following components in parts by mass: 0.1 parts of ergothioneine, 10 parts of plant extract, 1 part of asiatica glycoside and 4 parts of glutathione. The plant extract is a combination of a flower extract of Viola mandshurica and a cynanchum atratum extract, and the mass ratio of the flower extract of Viola mandshurica to the cynanchum atratum extract is 1:1-7.

2. Use of the anti-aging composition as claimed in claim 1 in skin care products.

3. The use according to claim 2, characterized in that The skin care product further comprises a solvent, and the solvent is any one of water and oil, or the solvent is a mixture of water and oil.

4. The use according to claim 3, characterized in that The skin care product may further include any one or more of an emulsifier, a preservative, a fragrance, a moisturizer, a pH regulator, a thickener, and a colorant.

5. The use according to claim 4, characterized in that The skin care product is any one of solid, liquid or semi-solid.

6. The use according to claim 5, characterized in that The skin care product also includes other functional components.

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