Natural acne-removing composition as well as preparation method and application thereof

Abstract

The invention relates to the technical field of cosmetics, and particularly discloses a natural acne-removing composition as well as a preparation method and application thereof. The natural acne-removing composition is prepared from the following raw materials in percentage by mass: 30 percent to 40 percent of butanediol, 0.5 percent to 1.5 percent of radix sophorae flavescentis extract, 0.5 percent to 1.5 percent of clausena lansium bark extract, 0.5 percent to 1.5 percent of camphor tree leaf extract, 0.5 percent to 1.5 percent of radix gentianae extract, 0.4 percent to 0.8 percent of fructus cnidii extract, 0.4 percent to 0.8 percent of chrysanthellum indicum extract, 0.4 percent to 0.8 percent of glycyrrhiza inflate root extract and the balance of water. According to the application of the natural acne-removing composition in cosmetics, the natural acne-removing composition is added into the cosmetics. The natural acne removal composition focuses on acne removal and skin repairing and conditioning at the same time, the acne problem is fundamentally solved, and acne regeneration is effectively prevented.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and in particular to a natural anti-acne composition, a preparation method and application thereof. Background Art

[0002] Acne, also known as acne, is a common skin problem with complex causes, which is affected by multiple factors such as endocrine disorders, excessive sebum secretion, blocked hair follicles, bacterial infection, excessive stress, external environmental stimulation, etc. In recent years, with the accelerated pace of life and the intensification of environmental pollution, skin problems, especially acne problems, have become increasingly serious, causing adverse effects on people's appearance and mental health.

[0003] The most effective conventional treatments for acne include hormone drugs and antihistamines. Among them, hormone drugs are the best anti-inflammatory and anti-allergic drugs, but hormone drugs have certain adverse reactions. Long-term or large-scale external use may cause increased hair growth, skin atrophy, etc. Although antihistamines have better anti-allergic effects, they can also cause adverse reactions such as drowsiness or mental fatigue, and long-term use may affect human health.

[0004] Nowadays, more and more consumers tend to choose acne-removing products with natural ingredients to reduce the potential damage of chemical ingredients to the skin. Although most natural acne-removing products on the market are gentle as their main selling point, the acne-removing effect is often unsatisfactory. Such products mostly use low-concentration plant extracts or natural ingredients. Although they are less irritating to the skin, the acne-removing effect is also weakened accordingly. During the use process, consumers often need to spend a lot of time and money to see slight improvements. Some products even fail to solve the fundamental problem at all, causing acne to grow repeatedly. Therefore, seeking natural, safe and effective acne-removing products has become the focus of consumers. Summary of the invention

[0005] In order to improve the effectiveness of natural acne removal products, the present application provides a natural acne removal composition and its preparation method and application. The natural acne removal composition of the present application focuses on both the removal of acne and the repair and conditioning of the skin, fundamentally solving the acne problem and effectively preventing the regeneration of acne.

[0006] In the first aspect, the present application provides a natural acne-removing composition using the following technical solution: A natural acne-removing composition comprises the following raw materials in percentage by mass: 30%-40% butylene glycol, 0.5%-1.5% sophora flavescens root extract, 0.5%-1.5% phellodendron chinense bark extract, 0.5%-1.5% camphor tree leaf extract, 0.5%-1.5% gentiana root extract, and the balance is water.

[0007] In the above technical scheme, Sophora flavescens (SOPHORA ANGUSTIFOLIA) root extract is extracted from the root of Sophora flavescens. As a traditional Chinese medicinal material, Sophora flavescens contains two major active ingredients, alkaloids and flavonoids. Among them, matrine and oxymatrine have anti-allergic and anti-inflammatory effects, and have a good effect on relieving skin itching. Therefore, Sophora flavescens has the effects of clearing away heat and dampness, killing insects and reducing inflammation, and is mainly used to treat eczema, skin itching, etc.

[0008] Phellodendron Chinese bark extract is extracted from the bark of Phellodendron Chinese tree. It is rich in alkaloids and flavonoids, and has the effects of drying dampness and clearing heat, detoxifying and purging fire, removing rot and reducing swelling.

[0009] Cinnamomum camphora leaf extract is extracted from the leaves of the camphor tree. The Tang Materia Medica records that "its fragrance is the best among all medicines, and there is no other fragrance that can match it." It can be seen that camphor leaves have a strong aroma and medicinal value. At the same time, camphor leaf extract can enhance the skin's absorption capacity and promote the skin to absorb more effective ingredients.

[0010] Gentiana (GENTIANASCABRA) root extract comes from the Gentianaceae family. Its roots are rich in active ingredients such as gentiopicroside, gentiana glycoside, kaempferol, etc. It has the effects of clearing away heat and detoxifying, reducing swelling and dispersing nodules. It has a good effect on alleviating symptoms such as skin redness, swelling, and pain caused by acne.

[0011] The present application, through the synergistic effect of Sophora flavescens root extract, Phellodendron chinense bark extract, Cinnamomum camphora leaf extract and Gentiana root extract, acts on acne together through the unique efficacy of Sophora flavescens root extract, Phellodendron chinense bark extract, Cinnamomum camphora leaf extract and Gentiana root extract, and realizes the removal of acne and the repair and conditioning of skin. First, Sophora flavescens root extract can effectively alleviate the inflammatory reaction caused by acne, and relieve skin itching and discomfort. Secondly, Phellodendron chinense bark extract helps to remove toxins and damp heat in the deep layer of the skin, creating favorable conditions for the disappearance of acne. Camphora leaf extract promotes other effective ingredients to penetrate into the bottom layer of the skin faster and more deeply by improving the absorption capacity of the skin, accelerating the healing process of acne. Finally, Gentiana root extract directly alleviates the symptoms such as redness, swelling and pain caused by acne, further consolidates the acne removal effect, and also well alleviates the irritation of the natural acne removal composition formula, making the natural acne removal composition more peaceful, more effective and safe to use.

[0012] In addition, the present application not only improves the system stability of the natural acne-removing composition by adding butylene glycol as a moisturizer and solvent to the natural acne-removing composition, but also helps to moisturize the skin and relieve the problem of dry skin caused by acne.

[0013] Preferably, the natural acne-removing composition comprises 35.1% butylene glycol, 1% Sophora flavescens root extract, 1% Phellodendron chinense bark extract, 1% Cinnamomum camphora leaf extract, and 1% Gentiana lutea root extract.

[0014] In the above technical solution, the present application further optimizes the dosage of each raw material of the natural anti-acne composition, further improves the synergistic effect of Sophora flavescens root extract, Phellodendron chinense bark extract, Cinnamomum camphora leaf extract and Gentiana root extract, and further improves the anti-acne effect and skin repair ability. At the same time, this ratio also further ensures the mildness and safety of the product, reducing skin irritation and adverse reactions.

[0015] Preferably, the natural anti-acne composition further comprises 0.4%-0.8% Cnidium monnieri extract.

[0016] In the above technical scheme, Cnidium monnieri fruit extract is extracted from the fruit of Cnidium monnieri, and Cnidium monnieri fruit is rich in various active ingredients, such as coumarins, flavonoids and volatile oils, etc. These ingredients are considered to have the effects of dispelling wind and dampness, killing insects and relieving itching, and warming the kidney and strengthening yang in traditional Chinese medicine theory. And in the natural anti-acne composition, these ingredients can further enhance the antibacterial and anti-inflammatory effects of the composition, and effectively inhibit the generation and spread of acne. The present application further adds Cnidium monnieri fruit extract on the basis of Sophora flavescens root extract, Phellodendron chinense bark extract, Cinnamomum camphora leaf extract and Gentiana root extract, which can better play the dual effects of acne removal and repair, better restore the healthy state of the skin, and reduce the formation of acne marks and acne pits.

[0017] Preferably, the natural anti-acne composition further comprises 0.4%-0.8% golden chamomile extract.

[0018] In the above technical solution, the CHRYSANTHELLUM INDICUM extract is extracted from golden chamomile, which has been widely praised for its skin soothing, inflammation relief and anti-allergic properties since ancient times. Golden chamomile extract is rich in a variety of active ingredients, such as flavonoids, caffeic acid, amino acids, etc. These ingredients have the effects of antibacterial and anti-inflammatory, analgesic and swelling relief, wound healing and cell regeneration. The golden chamomile extract is further added to the natural acne-removing composition, and the golden chamomile extract can play a good repairing effect, effectively reduce the problem of skin redness, and enhance the overall soothing effect of the natural acne-removing composition.

[0019] Preferably, the natural anti-acne composition further comprises 0.4%-0.8% of Glycyrrhiza inflata root extract.

[0020] In the above technical scheme, the Glycyrrhiza uralensis (Glycyrrhiza uralensis) root extract is extracted from the root of Glycyrrhiza uralensis, which is rich in triterpenes (glycyrrhizic acid, etc.), polyacetylenes and volatile oil components. In traditional Chinese medicine theory, it is often used as a herbal medicine for clearing away heat and detoxifying, relieving pain and harmonizing various medicines.

[0021] The present invention further adds Glycyrrhiza inflata root extract to the natural acne-removing composition, which can further enhance its anti-inflammatory effect and help alleviate skin inflammation and redness caused by acne. At the same time, ingredients such as glycyrrhizic acid can also promote the repair and regeneration of skin cells, help improve the condition of skin damaged by acne, and reduce the formation of acne marks and acne pits.

[0022] In addition, the addition of Glycyrrhiza inflata root extract can also work synergistically with Gentiana root extract to further enhance the mildness and safety of the natural anti-acne composition, reduce irritation and discomfort to the skin, and make the natural anti-acne composition more gentle, more effective and safer to use.

[0023] Preferably, the natural acne-removing composition comprises the following raw materials in percentage by mass: 30%-40% butylene glycol, 0.5%-1.5% Sophora flavescens root extract, 0.5%-1.5% Phellodendron chinense bark extract, 0.5%-1.5% Cinnamomum camphora leaf extract, 0.5%-1.5% Gentiana scabra root extract, 0.4%-0.8% Cnidium monnieri extract, 0.4%-0.8% Matricaria recutita extract, 0.4%-0.8% Glycyrrhiza uralensis root extract, and the balance is water.

[0024] In the above technical scheme, the present application selects the synergistic effect of Sophora flavescens root extract, Phellodendron bark extract, Camphor leaf extract, Gentiana root extract, Cnidium monnieri extract, Golden chamomile extract, and Glycyrrhiza uralensis root extract, and through their respective unique effects, they act together on acne, realizing the multi-dimensional treatment of acne and comprehensive repair of the skin. The present application found in the study that the acne removal and repair effects of the compounding of Sophora flavescens root extract, Phellodendron bark extract, Camphor leaf extract, Gentiana root extract, Cnidium monnieri extract, Golden chamomile extract, and Glycyrrhiza uralensis root extract are far greater than the effects of these raw materials when used separately or with other raw materials. In this regard, the present application further studied and found that the combination of Sophora flavescens root extract, Phellodendron bark extract, Camphor leaf extract, Gentiana root extract, Cnidium monnieri extract, Golden chamomile extract, and Glycyrrhiza uralensis root extract, these 7 kinds of raw materials, can form a rich target for the skin through the interaction network, comprehensively and accurately solve the acne problem and repair the skin. Specifically, the present application screened out 153 active ingredients and 88 intersection genes that are effective for acne problems from seven raw materials, namely, Sophora flavescens root extract, Phellodendron chinense bark extract, Cinnamomum camphora leaf extract, Gentiana root extract, Cnidium monnieri extract, Matricaria recutita extract, and Glycyrrhiza uralensis root extract. These active ingredients, under the synergistic effect, significantly enhanced the bioavailability and effectiveness of the natural acne-removing composition on the skin through the protein interaction network of the intersection genes. They can effectively penetrate into the bottom layer of the skin, intervene in multiple links of acne formation, solve the acne problem from the source, and accelerate the skin's self-repair process.

[0025] In the second aspect, the present application provides a method for preparing a natural acne-removing composition using the following technical solution: A method for preparing a natural acne-removing composition comprises: adding various extracts to butanediol in sequence, stirring until uniformly dissolved, and then adding the remaining amount of water to obtain the natural acne-removing composition.

[0026] In the above technical scheme, the present application adopts a simple dissolution and mixing process, which not only ensures the uniform dispersion and effective mixing of the raw materials, thereby ensuring the stability and consistency of the final product, but also makes the preparation process simple, efficient and easy to control, which is conducive to the industrial production of natural acne-removing compositions.

[0027] In a third aspect, the application of a natural acne-removing composition provided in the present application adopts the following technical solution: The invention discloses an application of a natural acne-removing composition in cosmetics, wherein the acne-removing composition is added into the cosmetics.

[0028] In the above technical solution, the present application can significantly improve the acne removal and repair effects of the product by applying the above natural acne removal composition to cosmetics, providing consumers with a more comprehensive and gentle skin care experience.

[0029] Preferably, the natural anti-acne composition is added in an amount of 1%-10% in cosmetics.

[0030] In the above technical solution, the present application not only ensures the optimal efficacy and stability of the natural acne-removing composition in the product, but also better controls the production cost of the cosmetics by limiting the amount of the natural acne-removing composition added to the cosmetics.

[0031] In summary, the present application includes at least one of the following beneficial technical effects: 1. The natural acne-removing composition provided by the present application achieves a comprehensive treatment of acne problems and deep repair of the skin through the interaction of seven raw materials: Sophora flavescens root extract, Phellodendron chinense bark extract, Cinnamomum camphora leaf extract, Gentiana root extract, Cnidium monnieri fruit extract, Matricaria recutita extract, and Glycyrrhiza uralensis root extract. The difference between the natural acne-removing composition of the present application and the common acne-removing products on the market is that the natural acne-removing composition of the present application can not only effectively remove acne, but also significantly reduce the formation of acne marks and acne pits, help the skin restore to a healthy state, and reduce the possibility of acne recurrence.

[0032] 2. The natural anti-acne composition of the present application can be flexibly added to cosmetics, such as lotions, emulsions, creams, essences, facial masks, etc., and the amount added can also be adjusted according to product needs. The natural anti-acne composition of the present application can significantly enhance the acne removal and repair effects of cosmetics, allowing consumers to enjoy beauty while also feeling the comfort and improvement of their skin. DETAILED DESCRIPTION

[0033] In order to better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments.

[0034] The sources of some substances in the examples are shown in Table 1: Example 1 A natural acne-removing composition comprises 59.1 kg of water, 35.1 kg of butylene glycol, 1 kg of sophora flavescens root extract, 1 kg of phellodendron chinense bark extract, 1 kg of camphor tree leaf extract, 1 kg of gentiana root extract, 0.6 kg of cnidium monnieri extract, 0.6 kg of golden chamomile extract, and 0.6 kg of glycyrrhiza inflata root extract.

[0035] Among them, Sophora flavescens root extract, Phellodendron chinense bark extract, Cinnamomum camphora leaf extract, Gentiana scabra root extract, Cnidium monnieri fruit extract, Matricaria recutita extract, and Glycyrrhiza uralensis root extract were all purchased from Shanghai Songhao Biotechnology Co., Ltd.

[0036] The preparation method of the natural acne-removing composition comprises: At 25°C, add Sophora flavescens root extract, Phellodendron chinense bark extract, Cinnamomum camphora leaf extract, Gentiana lutea root extract, Cnidium monnieri fruit extract, Matricaria recutita root extract, and Glycyrrhiza uralensis root extract to butylene glycol in sequence, stir until dissolved evenly, add the remaining amount of water, stir evenly, and obtain a natural acne-removing composition.

[0037] Example 2 A natural acne-removing composition, which is different from Example 1 in that it includes 54 kg of water, 40 kg of butylene glycol, 1.5 kg of Sophora flavescens root extract, 0.5 kg of Phellodendron chinense bark extract, 1.5 kg of Cinnamomum camphora leaf extract, 0.5 kg of Gentiana scabra root extract, 0.8 kg of Cnidium monnieri fruit extract, 0.4 kg of Matricaria recutita extract, and 0.8 kg of Glycyrrhiza uralensis root extract.

[0038] Example 3 A natural acne-removing composition, which is different from Example 1 in that it includes 64.4 kg of water, 30 kg of butylene glycol, 0.5 kg of Sophora flavescens root extract, 1.5 kg of Phellodendron chinense bark extract, 0.5 kg of Cinnamomum camphora leaf extract, 1.5 kg of Gentiana scabra root extract, 0.4 kg of Cnidium monnieri fruit extract, 0.8 kg of Matricaria recutita extract, and 0.4 kg of Glycyrrhiza uralensis root extract.

[0039] Example 4 A natural acne-removing composition, which is different from Example 1 in that an equal amount of Cnidium monnieri extract is replaced by a dandelion extract, and the dandelion (TARAXACUM MONGOLICUM) extract comes from Guangzhou Huayu Biotechnology Co., Ltd.

[0040] Example 5 A natural acne-removing composition, which is different from Example 1 in that an equal amount of golden chamomile extract is replaced by a Centella asiatica extract, and the Centella asiatica extract is derived from Shanghai Jiakai Biological Co., Ltd.

[0041] Example 6 A natural acne-removing composition, which is different from Example 1 in that an equal amount of Glycyrrhiza inflata root extract is replaced with Zanthoxylum bungeanum fruit extract, and the Zanthoxylum bungeanum fruit extract is sourced from Beijing Chenfeng Biotechnology Co., Ltd.

[0042] Example 7 A natural acne-removing composition, which is different from Example 1 in that equal amounts of golden chamomile extract and licorice root extract are replaced with water.

[0043] Example 8 A natural acne-removing composition, which is different from Example 1 in that equal amounts of Cnidium monnieri extract and Glycyrrhiza inflata root extract are replaced with water.

[0044] Example 9 A natural acne-removing composition, which is different from Example 1 in that equal amounts of Cnidium monnieri extract and Matricaria recutita extract are replaced with water.

[0045] Example 10 A natural acne-removing composition, which is different from Example 1 in that equal amounts of cnidium monnieri extract, golden chamomile extract, and glycyrrhiza inflata root extract are replaced with water.

[0046] Comparative Example 1 A natural acne-removing composition, which is different from Example 10 in that an equal amount of Sophora flavescens root extract is replaced with Matricaria recutita extract.

[0047] Comparative Example 2 A natural acne-removing composition, which is different from Example 10 in that an equal amount of the Phellodendron chinense bark extract is replaced with a Dictamnus usa root bark extract, and the Dictamnus usa root bark extract is sourced from Shaanxi Bolin Biotechnology Co., Ltd.

[0048] Comparative Example 3 A natural acne-removing composition, which is different from Example 10 in that an equal amount of camphor leaf extract is replaced with cnidium monnieri extract.

[0049] Comparative Example 4 A natural acne-removing composition, which is different from Example 10 in that an equal amount of gentiana root extract is replaced with Glycyrrhiza inflata root extract.

[0050] Application Example 1 A facial mask liquid comprises the following components: 81.23kg of water, 5kg of butylene glycol, 5kg of glycerol polyether-26, 1kg of betaine, 0.1kg of dipotassium glycyrrhizinate, 0.1kg of disodium ethylenediaminetetraacetic acid, 0.1kg of carbomer 941, 0.15kg of polyacrylate cross-linked polymer-6, 0.6kg of 1,2-hexanediol, 0.6kg of p-hydroxyacetophenone, 0.2kg of panthenol, 0.2kg of alcaligenes polysaccharide, 0.2kg of yeast / acetobacter xylinum / black tea fermentation product, 0.2kg of lotus water, 0.1kg of arginine, 0.05kg of beta-glucan, 0.05kg of olive leaf extract, 0.1kg of carbohydrate isomers, 0.01kg of hexapeptide-5, 0.01kg of palmitoyl tripeptide-8, and 10kg of a natural acne-removing composition.

[0051] Among them, the natural acne-removing composition is prepared by Example 1.

[0052] Wherein, the preparation method of facial mask liquid comprises the following steps: Step 1: Weigh water, butylene glycol, glyceryl polyether-26, betaine, dipotassium glycyrrhizinate, disodium EDTA, carbomer 941, polyacrylate crosspolymer-6, 1,2-hexanediol, and p-hydroxyacetophenone, add them into an emulsifier in sequence, heat to 85°C, homogenize at 45Hz for 5min, stir evenly at 25Hz, and keep warm for 30min.

[0053] Step 2: Cool down to 60°C, add panthenol, Alcaligenes polysaccharides, yeast / acetobacter xylinum / black tea fermentation products, and lotus water into the emulsifier in turn, stir at 25Hz for 5 minutes, then add arginine, β-glucan, olive leaf extract, carbohydrate isomers, hexapeptide-5, and palmitoyl tripeptide-8, and stir evenly at 25Hz.

[0054] Step 3: Continue to cool down to 45°C, add the remaining raw materials into the emulsifying pot, stir evenly at 25Hz, cool down to 38°C, discharge the material, and obtain the facial mask liquid.

[0055] Application Example 2 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Example 2.

[0056] Application Example 3 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Example 3.

[0057] Application Example 4 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Example 4.

[0058] Application Example 5 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Example 5.

[0059] Application Example 6 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Example 6.

[0060] Application Example 7 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Example 7.

[0061] Application Example 8 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Example 8.

[0062] Application Example 9 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Example 9.

[0063] Application Example 10 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Example 10.

[0064] Comparative application example 1 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Comparative Example 1.

[0065] Comparative Application Example 2 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Comparative Example 2.

[0066] Comparative Application Example 3 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Comparative Example 3.

[0067] Comparative Application Example 4 A facial mask liquid, which is different from Application Example 1 in that the natural acne-removing composition is prepared by Comparative Example 4.

[0068] Comparative Application Example 5 A facial mask liquid, which is different from Application Example 1 in that an equal amount of the natural acne-removing composition is replaced with water.

[0069] Efficacy testing Sample: the facial mask liquid of the above-mentioned application examples and comparative application examples.

[0070] Subject screening: 150 subjects were selected and divided into 15 groups, with 10 subjects in each group. The subjects were aged 18 to 45 years old, healthy men or women, in good health, and had acne scores between 3 and 4 according to the ISGA scale (see Table 1). At the same time, subjects with acne scores above 4 according to the ISGA scale (see Table 1) were excluded.

[0071] Detection method: No products can be used on the day of the test site inspection (D0, D7, D28). Before the test, the subjects need to clean their faces uniformly, dry them with dandruff-free facial tissues, and sit quietly in the human efficacy evaluation room (temperature: 20℃~22℃, humidity: 40%-60%) for 30 minutes, during which time they cannot drink water or beverages.

[0072] Daily use: After cleansing your face at night, take out the mask cloth that has been completely soaked in the mask liquid, unfold it and gently apply it to your face, adjust the position of the mask cloth and use your fingers to remove the bubbles in the mask. After it fits well, let it sit for 20 minutes before removing it and cleaning it with clean water. Use it every other day, one piece each time, for 28 consecutive days. During the trial, subjects are prohibited from using soothing, repairing, acne-removing, anti-inflammatory and antibacterial preparations; subjects are prohibited from taking preparations that affect soothing, repairing and acne-removing tests by drip, injection, oral or other forms; subjects are mainly indoors and avoid long-term exposure to outdoor light.

[0073] Test items: 1. Safety and adverse reaction evaluation: During the test, professional dermatologists asked the subjects whether they experienced dryness, oiliness, desquamation, redness, stinging and other symptoms during the use of the tested products, and observed and recorded whether there were rashes, redness, swelling and desquamation on the face. Then the scores were scored according to the scoring criteria in Table 2, and the scores were recorded in the event report form. According to the tests during the test, the scores of all groups of subjects were 0, and no subjects had adverse reactions, which proved that the samples used in this test were mild and non-irritating.

[0074] 2. ISGA score: Dermatologists evaluated the acne lesions on the subjects' faces in the photos before and after the subjects used the product. The ISGA scale was used to score the improvement of the lesion symptoms before and after the subjects used the product, and the percentage of lesion reduction was calculated. Percentage of lesion reduction (%) = (ISGA score before using the product - ISGA score after using the product) / ISGA score before using the product × 100%. The test results were averaged, see Table 3.

[0075] 3. Acne volume analysis: The acne area images taken by Antera 3D are analyzed by software to measure the changes in facial acne volume at different time points. Acne volume change rate (%) = (acne volume before using the product - acne volume after using the product) / acne volume before using the product × 100%. The test results are averaged, see Table 4.

[0076] 4. Hemoglobin concentration analysis: The acne area images taken by Antera 3D are analyzed by software to measure the changes in facial hemoglobin concentration at different time points. By comparing the changes in hemoglobin concentration before and after use, the acne removal effect of the product can be reflected. Hemoglobin concentration change rate (%) = (hemoglobin concentration before use of the product - hemoglobin concentration after use of the product) / hemoglobin concentration before use of the product × 100%. The test results are averaged, see Table 5.

[0077] 5. Analysis of TEWL value of skin: The larger the TEWL value measured by Tewameter TM Hex, the more TEWL loss per unit time and per unit cross-sectional area, and vice versa. Therefore, the trend of TEWL value decrease represents the recovery process of TEWL of barrier damaged skin. TEWL value change rate (%) = (TEWL value before using the product - TEWL value after using the product) / TEWL value before using the product × 100%. The test results are averaged, see Table 6.

[0078] Table 1: ISGA scale Table 2: Scoring criteria for adverse reactions Table 3: Table 4: Table 5: Table 6: From the above experimental data analysis of the corresponding application examples 1-10 and the comparative application examples 1-5, it can be seen that the application examples 1-10 have good acne removal effects and skin repair capabilities. Specifically, the application examples 1-10 have good effects of eliminating acne, reducing facial redness, and enhancing facial barrier function.

[0079] Specifically combining the analysis of Application Example 10 and Comparative Application Examples 1-5, the difference between Comparative Application Examples 1-5 and Application Example 10 is that Comparative Application Examples 1-4 respectively replaced the Sophora flavescens root extract, the Phellodendron chinense bark extract, the Cinnamomum camphora leaf extract, and the Gentiana root extract, and Comparative Application Example 5 did not add the natural acne-removing composition. It can be seen that Application Example 1 has good effects in acne removal and skin repair. It can be seen that the present application can significantly improve the acne removal effect and skin repair ability of the natural acne-removing composition through the compounding of Sophora flavescens root extract, the Phellodendron chinense bark extract, the Cinnamomum camphora leaf extract, and the Gentiana root extract.

[0080] Specifically combining the analysis of Application Example 1 and Application Examples 4-9, the difference between Application Examples 4-6 and Application Example 1 is that cnidium monnieri extract, golden chamomile extract, and glycyrrhiza uralensis root extract are replaced respectively, and the difference between Application Examples 7-9 and Application Example 1 is that only cnidium monnieri extract, golden chamomile extract, and glycyrrhiza uralensis root extract are added respectively. It can be seen that Application Example 1 has good effects in removing acne and repairing skin. It can be seen that in Application Example 1, the selection of Sophora flavescens root extract, Phellodendron chinense bark extract, Cinnamomum camphora leaf extract, Gentiana root extract, cnidium monnieri extract, golden chamomile extract, and glycyrrhiza uralensis root extract is special, and these 7 have better synergistic effects, so that the overall effect is better than a single ingredient or a combination of other similar raw materials. Through the interaction of these 7 raw materials, the present application achieves all-round treatment of acne problems and deep repair of the skin, and shows significant effects in reducing skin lesions, reducing acne volume, reducing hemoglobin concentration, and restoring skin barrier function, and the effect gradually increases over time.

[0081] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed, but such modifications are protected by the patent law as long as they are within the scope of the claims of the present application.

Claims

1. A natural acne-removing composition, characterized in that: The invention comprises the following raw materials in percentage by weight: 30%-40% butylene glycol, 0.5%-1.5% sophora flavescens root extract, 0.5%-1.5% phellodendron chinense bark extract, 0.5%-1.5% camphor tree leaf extract, 0.5%-1.5% gentiana root extract, and the balance is water.

2. A natural anti-acne composition according to claim 1, characterized in that: Including 35.1% butylene glycol, 1% Sophora flavescens root extract, 1% Phellodendron chinense bark extract, 1% Cinnamomum camphora leaf extract, and 1% Gentiana lutea root extract.

3. A natural acne-removing composition according to claim 1, characterized in that: Also includes 0.4%-0.8% Cnidium monnieri extract.

4. A natural anti-acne composition according to claim 1, characterized in that: Also includes 0.4%-0.8% golden chamomile extract.

5. A natural acne-removing composition according to claim 1, characterized in that: Also included is 0.4%-0.8% Glycyrrhiza inflata root extract.

6. A method for preparing the natural anti-acne composition according to any one of claims 1 to 5, characterized in that: include: The extracts are added to butanediol in sequence, stirred until uniformly dissolved, and then the remaining amount of water is added to obtain a natural acne-removing composition.

7. Use of the natural anti-acne composition according to any one of claims 1 to 5 in cosmetics, characterized in that: Add it to your cosmetics.

8. Use of a natural anti-acne composition in cosmetics according to claim 7, characterized in that: The natural anti-acne composition is added in an amount of 1%-10% in cosmetics.

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