A cerebrospinal fluid sampling and detection device for neurology

Abstract

The present invention discloses a cerebrospinal fluid sampling and detection device for neurology, and relates to the detection technology field of auxiliary diagnosis of neurological diseases. The present invention comprises a device body, a sampling device is arranged on one side of the device body, a measuring component is arranged on the top of the device body, and a gas injection device is arranged inside the device body. The present invention, through the arrangement of the sampling device, allows the interior of the liquid storage tube to be filled with the required cerebrospinal fluid, and no gaps are left, thereby ensuring that the cerebrospinal fluid in the liquid storage tube is the expected amount, and at the same time, the hollow plug rod, the liquid storage tube, the connecting tube, and the device body cooperate, so that the hollow plug rod fits the inner wall of the liquid storage tube, and the hollow plug rod will inject all the cerebrospinal fluid into the device body, thereby avoiding the residue of cerebrospinal fluid, resulting in the actual amount of cerebrospinal fluid injected into the device body being lower than expected, resulting in insufficient concentration of the final sample, affecting the problem of test results.

Description

Technical Field

[0001] The present invention relates to the technical field of detection of auxiliary diagnosis of neurological diseases, and in particular to a cerebrospinal fluid sampling detection device for neurology. Background Art

[0002] Cerebrospinal fluid is a transparent liquid that exists between the ventricles, spinal canal and meninges, and has a buffering and protective effect. It can provide nutrition to the brain and spinal cord, remove metabolic waste, and maintain stable pressure in the brain. Abnormal changes in cerebrospinal fluid are often related to neurological diseases. The hydrogen sulfide content in cerebrospinal fluid is a reference for diagnosing many diseases, so a sampling detection device is used to measure the hydrogen sulfide content in cerebrospinal fluid.

[0003] The Chinese patent with patent announcement number CN115541861B discloses a neurological body fluid sampling and detection device, which relates to the detection field of auxiliary diagnosis of neurological diseases, and specifically to a device for detecting the content of hydrogen sulfide in cerebrospinal fluid, including a sampling component, a reaction component and a measurement component; the sampling component is used to quantitatively extract cerebrospinal fluid; the reaction component provides a reaction space for cerebrospinal fluid and phosphoric acid; the measurement component provides a reaction space for hydrogen sulfide and sodium hydroxide, the sampling component includes a tank body, the tank body is used to contain cerebrospinal fluid; the reaction component includes a box body, the top surface of the box body is connected to the tank body, so that the cerebrospinal fluid in the tank body can flow into the box body; the measurement component includes a bottle body, the bottle body is connected to the top surface of the box body, so that hydrogen sulfide gas can enter the bottle body. The detection device is easy to use, fully reacts, and the reaction process is finely controllable.

[0004] However, the current sampling and detection device has the following problems: when the sampling and detection device injects cerebrospinal fluid into a box containing phosphoric acid through an inner bag, cerebrospinal fluid is likely to remain inside the inner bag. The cerebrospinal fluid remaining in the inner bag will cause the actual amount of cerebrospinal fluid injected into the detection box to be lower than expected, resulting in insufficient concentration of the final sample. If the detection analysis relies on precise concentration, the concentration of the components in the sample may be inaccurate, thereby affecting the test results. Therefore, we propose a cerebrospinal fluid sampling and detection device for neurology. Summary of the invention

[0005] In view of the deficiencies in the prior art, the present invention provides a cerebrospinal fluid sampling and detection device for neurology, which solves the problems raised in the above-mentioned background technology.

[0006] To achieve the above objectives, the present invention is implemented through the following technical solutions: a cerebrospinal fluid sampling and detection device for neurology, comprising a device body, wherein phosphoric acid is filled inside the device body, a liquid inlet pipe is fixed on the top of the device body, a liquid discharge pipe is fixed on the side of the device body, and a valve is arranged in the middle of the liquid discharge pipe, a sampling device is arranged on one side of the device body, a measuring component for measuring hydrogen sulfide content is arranged on the top of the device body, and a gas injection device for injecting hydrogen sulfide gas into the measuring component is arranged inside the device body, the sampling device comprises a cross frame, the cross frame is fixed to the bottom of the device body, a liquid storage tube is fixed at one end of the cross frame away from the device body, and the liquid storage tube is arranged in an inclined shape, a scale is arranged on the outside of the liquid storage tube, a hollow plug rod is slidably installed inside the liquid storage tube, and a one-way liquid inlet pipe is fixed inside the hollow plug rod, cerebrospinal fluid is injected into the liquid storage tube through the cavity of the hollow plug rod, and the one-way liquid inlet pipe will The flow direction of cerebrospinal fluid is restricted to prevent the cerebrospinal fluid in the liquid storage tube from flowing out of the liquid storage tube through the cavity of the hollow plug rod. An exhaust pipe is fixed on the top of the liquid storage tube, and a floating ball is arranged inside the liquid storage tube. The liquid storage tube is connected to the device body through a connecting pipe, and an opening and closing valve is arranged in the middle of the connecting pipe. The floating ball is located on the side of the hollow plug rod close to the device body. A circular cavity for accommodating the floating ball is opened at the bottom of the exhaust pipe. Under the action of buoyancy, the cerebrospinal fluid in the liquid storage tube will be carried away. The dynamic float rises. Since the liquid storage tube is set at an angle, as the cerebrospinal fluid in the hollow plug rod increases, the float floats to the bottom of the exhaust pipe, and then the float moves into the circular cavity of the exhaust pipe. The float will close the exhaust pipe. At this time, the inside of the liquid storage tube is filled with the required cerebrospinal fluid, and no gaps will be left, thereby ensuring that the cerebrospinal fluid in the liquid storage tube is the expected amount. Then open the opening and closing valve and push the hollow plug rod. The hollow plug rod will squeeze the cerebrospinal fluid in the liquid storage tube and inject it into the device body through the connecting tube.

[0007] According to the above technical solution, the sampling device includes a trapezoidal protrusion disk and a trapezoidal recessed disk. The trapezoidal protrusion disk is fixed on the side of the hollow plug rod close to the device body, and the trapezoidal recessed disk is fixed on the inner wall of the liquid storage tube. The trapezoidal protrusion disk and the trapezoidal recessed disk are arranged opposite to each other. At the same time, when the float floats to the bottom of the exhaust pipe, the concave surface of the trapezoidal recessed disk will guide the float to the bottom of the exhaust pipe.

[0008] According to the above technical solution, the measuring assembly includes a measuring cylinder, a cylinder cover, a plug disc, a ring frame, four U-shaped tubes, four sliding columns, and four floating blocks. The measuring cylinder is fixed on the top of the device body, and the interior of the measuring cylinder is filled with sodium hydroxide solution. The cylinder cover is threadedly connected to the top of the measuring cylinder, and the plug disc is fixed on the lower inner wall of the measuring cylinder. One end of the four U-shaped tubes is respectively uniformly penetrated and fixed on the top of the plug disc, and the other ends of the four U-shaped tubes are all located inside the measuring cylinder. The four sliding columns are respectively uniformly penetrated and slidably installed on the top of one side of the four U-shaped tubes close to the plug disc. The ring frame is fixed between the tops of the four sliding columns, and the four floating blocks are respectively fixed at At the bottom of the four sliding columns, after the cerebrospinal fluid is injected into the device body through the connecting tube, the cerebrospinal fluid will react with the phosphoric acid in the device body, and the hydrogen sulfide generated by the reaction will be injected into the U-shaped tube through the gas injection device. The U-shaped tube injects the hydrogen sulfide into the sodium hydroxide solution in the measuring tube for reaction, and then the tube cover is opened, and the reacted sodium hydroxide solution in the measuring tube is collected with a pipette, so as to quickly complete the extraction of hydrogen sulfide in the cerebrospinal fluid sample. When the gas injection device pushes the liquid level of the phosphoric acid solvent in the device body to the floating block, under the action of buoyancy, the phosphoric acid solvent in the device body will drive the floating block to float, and the floating block drives the sliding column to move upward, and the sliding column drives the ring frame to move upward until the floating block blocks the U-shaped tube.

[0009] According to the above technical scheme, the measuring component also includes four strong magnetic blocks one, four strong magnetic blocks two, and four fixed frames. The four strong magnetic blocks one are respectively fixed at the four corners of the top of the ring frame, the four fixed frames are respectively and evenly fixed on the upper inner wall of the measuring tube, and the four strong magnetic blocks two are respectively fixed at the bottom of the four fixed frames. The strong magnetic block one and the strong magnetic block two are arranged opposite to each other, and the magnetic forces of the strong magnetic block one and the strong magnetic block two attract each other. When the ring frame moves upward, the strong magnetic block one will be driven to move with it. When the strong magnetic block one moves to the strong magnetic block two, under the action of the magnetic forces of the strong magnetic block one and the strong magnetic block two, the strong magnetic block two will adsorb the strong magnetic block one, so that the strong magnetic block two limits the position of the ring frame through the strong magnetic block one, and the ring frame limits the position of the floating block through the sliding column.

[0010] According to the above technical solution, the gas injection device includes an electric push rod and a push plate. The electric push rod is fixed at the bottom of the device body, and the push plate is slidably installed inside the device body. The top of the telescopic end of the electric push rod is fixedly connected to the bottom of the push plate. When the gas injection device is in use, the electric push rod is started, and the telescopic end of the electric push rod pushes the push plate to move upward along the inner wall of the device body. The push plate pushes the solvent inside the device body to move upward. During this process, hydrogen sulfide generated by the reaction in the device body will be injected into the U-shaped tube.

[0011] According to the above technical solution, the gas injection device also includes two rotating rods, two spiral blades, and four friction wheels. The two rotating rods are rotatably installed on both sides of the top of the push plate through brackets, and the two spiral blades are respectively fixed at the middle outer walls of the two rotating rods. The four friction wheels are respectively fixed at both ends of the two rotating rods. The outer walls of the friction wheels are set as rough surfaces, and the inner walls of the device body on both sides are set as rough surfaces. The rough surfaces of the friction wheels are in contact with the rough surfaces of the device body. At the same time, when the push plate moves upward, the friction wheels will be driven to move upward through the rotating rod. Under the action of the friction force between the friction wheel and the inner wall of the device body, the friction wheel will rotate during the movement, and the friction wheel drives the rotating rod to rotate, and the rotating rod drives the spiral blades to rotate, so that the spiral blades stir the cerebrospinal fluid and phosphoric acid in the device body.

[0012] According to the above technical solution, an elliptical groove disk is fixed to the outside of the rotating rod on one side, a U-shaped frame is fixed to the top of the pushing plate, a slide plate is slidably installed on one side of the U-shaped frame, and a plurality of moving rods are penetrated and slidably installed on the top of the slide plate, and long floats are fixed on the tops of the plurality of moving rods, and the two sides of the long floats are triangularly arranged, and the triangular shape of the long floats is an inclined arrangement that decreases from the sampling device toward the direction of the measuring component, and an L-shaped connecting rod is fixed to one end of the slide plate, and the end of the L-shaped connecting rod away from the slide plate is slidably connected to the inside of the elliptical groove disk, and the moving rod, L-shaped connecting rod and U-shaped frame are all retractable structures. At the same time, the long float is affected by the buoyancy of the solvent inside the device body, and the long float will It floats on the surface of the solvent inside the device body. During this process, the long float drives the moving rod to move upward, and when the rotating rod rotates, it will drive the elliptical groove plate to rotate. The elliptical groove plate will push the L-shaped connecting rod to drive the slide plate to move back and forth along the outer wall of the U-shaped frame. The U-shaped frame drives the long float to move back and forth through the moving rod. When the push plate pushes the solvent inside the device body to the top of the inner wall of the device body, the long float will immediately contact the top of the inner wall of the device body. The hydrogen sulfide generated by the reaction in the device body will be injected into the U-shaped tube. In the process, some bubbles will remain on the top of the inner wall of the device body. These bubbles will contain some hydrogen sulfide that cannot be injected into the U-shaped tube. At this time, the reciprocating movement of the long float can scrape the bubbles on the top of the inner wall of the device body.

[0013] The present invention provides a cerebrospinal fluid sampling and detection device for neurology, which has the following beneficial effects:

[0014] (1) The present invention arranges the sampling device so that the hollow plug rod, the liquid storage tube, the one-way liquid inlet tube, the float ball, and the exhaust pipe cooperate with each other, so that the interior of the liquid storage tube is filled with the required cerebrospinal fluid without leaving any gaps, thereby ensuring that the cerebrospinal fluid in the liquid storage tube is the expected amount. At the same time, the hollow plug rod, the liquid storage tube, the connecting tube, and the device body cooperate with each other so that the hollow plug rod fits the inner wall of the liquid storage tube. The hollow plug rod will inject all the cerebrospinal fluid into the device body, thereby avoiding the problem that the cerebrospinal fluid residue appears, resulting in the actual amount of cerebrospinal fluid injected into the device body being lower than expected, resulting in insufficient concentration of the final sample, and affecting the test results. At the same time, the concave surface of the trapezoidal notch disk will guide the float ball to the bottom of the exhaust pipe, thereby ensuring that the float ball can effectively enter the circular cavity of the exhaust pipe and avoiding the float ball from deviating from the exhaust pipe during movement.

[0015] (2) The present invention arranges the measuring components so that the connecting tube, the device body, and the gas injection device cooperate to drive the U-shaped tube to inject hydrogen sulfide into the sodium hydroxide solution of the measuring tube for reaction. At the same time, the tube cover, the measuring tube, the gas injection device, the device body, the floating block, the sliding column, and the ring frame cooperate to drive the floating block to block the U-shaped tube, thereby avoiding the problem that the gas injection device pushes the phosphoric acid solvent in the device body to be injected into the measuring tube through the U-shaped tube, thereby affecting the detection result; at the same time, the ring frame, the strong magnetic block 1, and the strong magnetic block 2 cooperate to drive the strong magnetic block 2 to adsorb the strong magnetic block 1, so that the strong magnetic block 2 limits the position of the ring frame through the strong magnetic block 1, and the ring frame limits the position of the floating block through the sliding column, which is conducive to the floating block blocking the U-shaped tube. At the same time, it is avoided that during the process of collecting the sodium hydroxide solution with the pipette gun, the pipette gun touches the ring frame, and the ring frame pushes the sliding column to drive the floating block to move downward, resulting in the problem of loose sealing between the floating block and the U-shaped tube.

[0016] (3) The present invention sets a gas injection device so that the electric push rod drives the push plate to push the solvent inside the device body to move upward, and the hydrogen sulfide generated by the reaction in the device body will be injected into the U-shaped tube, thereby improving the efficiency of collecting hydrogen sulfide into the measuring tube; at the same time, the push plate, the rotating rod, the friction wheel, and the rotating rod cooperate to drive the spiral blades to stir the cerebrospinal fluid and phosphoric acid in the device body. The stirring of the spiral blades can increase the collision frequency of substances in the solution and promote the reaction, which helps to improve the reaction efficiency and complete the reaction in a shorter time; at the same time, the long float, the device body, the moving rod, the rotating rod, the elliptical groove plate, the L-shaped connecting rod, the slide plate, the U-shaped frame, and the push plate cooperate to drive the long float to scrape the bubbles on the top of the inner wall of the device body, and under the guidance of the triangular inclined part of the long float, these bubbles move toward the direction of the U-shaped tube, thereby avoiding the problem of hydrogen sulfide bubbles being retained in the device body and causing abnormal cerebrospinal fluid measurement. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 A schematic diagram of the present invention as a whole;

[0018] Figure 2 It is a partial cross-sectional schematic diagram of the present invention;

[0019] Figure 3 Schematic diagram of the sampling device of the present invention Figure 1 ;

[0020] Figure 4 Schematic diagram of the sampling device of the present invention Figure 2 ;

[0021] Figure 5 Schematic diagram of the measuring assembly of the present invention Figure 1 ;

[0022] Figure 6 Schematic diagram of the measuring assembly of the present invention Figure 2 ;

[0023] Figure 7 is a schematic diagram of a gas injection device according to the present invention;

[0024] Figure 8 It is a schematic diagram of the partial structure of the gas injection device of the present invention.

[0025] In the figure: 1. device body; 2. sampling device; 21. cross frame; 22. liquid storage tube; 23. hollow plug rod; 24. one-way liquid inlet pipe; 25. exhaust pipe; 26. float; 27. opening and closing valve; 28. connecting pipe; 29. ​​trapezoidal raised disk; 210. trapezoidal recessed disk; 3. measuring assembly; 31. measuring cylinder; 32. cylinder cover; 33. U-shaped tube; 34. sliding column; 35. plug disk; 36. floating block; 37. ring frame; 38. strong magnetic block 1; 39. strong magnetic block 2; 310. fixed frame; 4. gas injection device; 41. electric push rod; 42. push plate; 43. rotating rod; 44. spiral blade; 45. friction wheel; 46. elliptical groove disk; 47. moving rod; 48. L-shaped connecting rod; 49. U-shaped frame; 410. slide plate; 411. long float. DETAILED DESCRIPTION

[0026] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0027] See also Figure 1 - Figure 8One embodiment of the present invention is: a cerebrospinal fluid sampling and detection device for neurology, comprising a device body 1, wherein phosphoric acid is contained in the device body 1, a liquid inlet pipe is fixed on the top of the device body 1, a liquid discharge pipe is fixed on the side of the device body 1, and a valve is arranged in the middle of the liquid discharge pipe, a sampling device 2 is arranged on one side of the device body 1, a measuring component 3 for measuring hydrogen sulfide content is arranged on the top of the device body 1, and a valve is arranged inside the device body 1 for injecting hydrogen sulfide gas into the measuring component 3 The gas injection device 4, the sampling device 2 includes a cross frame 21, the cross frame 21 is fixed to the bottom of the device body 1, the end of the cross frame 21 away from the device body 1 is fixed with a liquid storage tube 22, and the liquid storage tube 22 is arranged in an inclined shape, the outside of the liquid storage tube 22 is provided with a scale, the inside of the liquid storage tube 22 is slidably installed with a hollow plug rod 23, and the inside of the hollow plug rod 23 is fixed with a one-way liquid inlet tube 24, the one-way liquid inlet tube 24 will limit the flow direction of cerebrospinal fluid, and prevent the cerebrospinal fluid in the liquid storage tube 22 from passing through the hollow plug rod The liquid flows out of the cavity of the liquid storage tube 23, and an exhaust pipe 25 is fixed on the top of the liquid storage tube 22. A floating ball 26 is arranged inside the liquid storage tube 22. The liquid storage tube 22 is connected to the device body 1 through a connecting pipe 28. An opening and closing valve 27 is arranged in the middle of the connecting pipe 28. The floating ball 26 is located on the side of the hollow plug rod 23 close to the device body 1. A circular cavity for accommodating the floating ball 26 is opened at the bottom of the exhaust pipe 25. Through the arrangement of the above structure, the floating ball 26 floats to the bottom of the exhaust pipe 25, and the floating ball 26 moves into In the circular cavity of the exhaust pipe 25, the float 26 will close the exhaust pipe 25. At this time, the interior of the liquid storage tube 22 is filled with the required cerebrospinal fluid, and no gaps will be left, thereby ensuring that the cerebrospinal fluid in the liquid storage tube 22 is the expected amount. At the same time, through the setting of the above-mentioned structure, the hollow plug rod 23 will inject all the cerebrospinal fluid into the device body 1, thereby avoiding the residue of cerebrospinal fluid, resulting in the actual amount of cerebrospinal fluid injected into the device body 1 being lower than expected, resulting in insufficient concentration of the final sample, affecting the test results.

[0028] The sampling device 2 includes a trapezoidal protrusion disk 29 and a trapezoidal recessed disk 210. The trapezoidal protrusion disk 29 is fixed on the side of the hollow plug rod 23 close to the device body 1, and the trapezoidal recessed disk 210 is fixed on the inner wall of the liquid storage tube 22. The trapezoidal protrusion disk 29 and the trapezoidal recessed disk 210 are arranged opposite to each other. Through the arrangement of the above structure, the concave surface of the trapezoidal recessed disk 210 will guide the float 26 to the bottom of the exhaust pipe 25, thereby ensuring that the float 26 can effectively enter the circular cavity of the exhaust pipe 25 and avoid the float 26 from deviating from the exhaust pipe 25 during movement.

[0029] The measuring assembly 3 includes a measuring cylinder 31, a cylinder cover 32, a plug disc 35, a ring frame 37, four U-shaped tubes 33, four slide columns 34, and four floats 36. The measuring cylinder 31 is fixed to the top of the device body 1. The interior of the measuring cylinder 31 is filled with sodium hydroxide solution. The cylinder cover 32 is threadedly connected to the top of the measuring cylinder 31. The plug disc 35 is fixed to the lower inner wall of the measuring cylinder 31. One end of the four U-shaped tubes 33 is uniformly penetrated and fixed to the top of the plug disc 35. The other ends of the four U-shaped tubes 33 are all located inside the measuring cylinder 31. The four slide columns 34 are uniformly The ring frame 37 is fixed between the tops of the four sliding columns 34, and the four floating blocks 36 are respectively fixed at the bottoms of the four sliding columns 34. Through the arrangement of the above structure, the U-shaped tube 33 injects hydrogen sulfide into the sodium hydroxide solution of the measuring tube 31 for reaction. At the same time, through the arrangement of the above structure, the floating block 36 blocks the U-shaped tube 33, thereby avoiding the problem that the gas injection device 4 pushes the phosphoric acid solvent in the device body 1 to be injected into the measuring tube 31 through the U-shaped tube 33, affecting the detection result.

[0030] The measuring assembly 3 also includes four strong magnetic blocks 1 38, four strong magnetic blocks 2 39, and four fixing frames 310. The four strong magnetic blocks 1 38 are respectively fixed at the four corners of the top of the ring frame 37, and the four fixing frames 310 are respectively fixed on the upper inner wall of the measuring tube 31 in a uniform manner. The four strong magnetic blocks 2 39 are respectively fixed at the bottom of the four fixing frames 310. The strong magnetic blocks 1 38 and the strong magnetic blocks 2 39 are relatively arranged, and the magnetic forces of the strong magnetic blocks 1 38 and the strong magnetic blocks 2 39 attract each other. Through the arrangement of the above structure, the strong magnetic block 2 39 will adsorb the strong magnetic block 1 38, so that the strong magnetic block 2 39 limits the position of the ring frame 37 through the strong magnetic block 1 38, and the ring frame 37 limits the position of the floating block 36 through the sliding column 34, which is conducive to the floating block 36 to block the U-shaped tube 33.

[0031] When in use, the hollow plug rod 23 is moved to the scale corresponding to the amount of cerebrospinal fluid that the liquid storage tube 22 needs to accommodate, and then the cerebrospinal fluid is injected into the liquid storage tube 22 through the cavity of the hollow plug rod 23. The one-way liquid inlet pipe 24 will restrict the flow direction of the cerebrospinal fluid, thereby preventing the cerebrospinal fluid inside the liquid storage tube 22 from flowing out of the liquid storage tube 22 through the cavity of the hollow plug rod 23. Under the action of buoyancy, the cerebrospinal fluid in the liquid storage tube 22 will drive the float ball 26 to float. Since the liquid storage tube 22 is arranged at an angle, the cerebrospinal fluid in the hollow plug rod 23 will flow out of the liquid storage tube 22. The amount of cerebrospinal fluid increases, the float 26 floats to the bottom of the exhaust pipe 25, and then the float 26 moves into the circular cavity of the exhaust pipe 25, and the float 26 closes the exhaust pipe 25. At this time, the interior of the liquid storage tube 22 is filled with the required cerebrospinal fluid, and no gaps are left, thereby ensuring that the cerebrospinal fluid in the liquid storage tube 22 is the expected amount, and then the opening and closing valve 27 is opened, and the hollow plug rod 23 is pushed. The hollow plug rod 23 squeezes the cerebrospinal fluid in the liquid storage tube 22 and injects it into the device body 1 through the connecting tube 28 until the hollow plug rod 23 and the hollow plug rod 23 are connected. The inner wall of the liquid storage tube 22 fits well, and the hollow plug rod 23 will inject all the cerebrospinal fluid into the device body 1, thereby avoiding the presence of cerebrospinal fluid residue, resulting in the actual amount of cerebrospinal fluid injected into the device body 1 being lower than expected, resulting in insufficient concentration of the final sample, affecting the test results; at the same time, when the float 26 floats to the bottom of the exhaust pipe 25, the concave surface of the trapezoidal notch disk 210 will guide the float 26 to the bottom of the exhaust pipe 25, thereby ensuring that the float 26 can effectively enter the circular cavity of the exhaust pipe 25, avoiding the float 26 from deviating from the exhaust pipe 25 during movement. It is worth noting that the cerebrospinal fluid detection operation is carried out in a sterile environment, and the device is disinfected each time the cerebrospinal fluid is detected. The sampling device 2 and the measuring component 3 here are both detachable, so that the disinfection operation of the sampling device 2 and the measuring component 3 before and after use can be facilitated. At the same time, when the device body 1 needs to be disinfected, the disinfectant cleaning solution can be poured into the device body 1 to disinfect the device body 1.

[0032] After the cerebrospinal fluid is injected into the device body 1 through the connecting tube 28, the cerebrospinal fluid will react with the phosphoric acid in the device body 1, and the hydrogen sulfide generated by the reaction will be injected into the U-shaped tube 33 through the gas injection device 4. The U-shaped tube 33 injects the hydrogen sulfide into the sodium hydroxide solution in the measuring tube 31 for reaction, and then the tube cover 32 is opened, and the reacted sodium hydroxide solution in the measuring tube 31 is collected with a pipette, that is, the extraction of hydrogen sulfide in the cerebrospinal fluid sample is quickly completed. When the gas injection device 4 pushes the liquid level of the phosphoric acid solvent in the device body 1 to reach the floating block 36, under the action of buoyancy, the phosphoric acid solvent in the device body 1 will drive the floating block 36 to float, and the floating block 36 drives the sliding column 34 to move upward, and the sliding column 34 drives the ring frame 37 to move upward until the floating block 36 blocks the U-shaped tube 33, thereby preventing the gas injection device 4 from pushing the device body 1 The phosphoric acid solvent is injected into the measuring tube 31 through the U-shaped tube 33, which affects the detection result; when the ring frame 37 moves upward, it will drive the strong magnetic block 1 38 to move with it. When the strong magnetic block 1 38 moves to the strong magnetic block 2 39, under the magnetic force of the strong magnetic block 1 38 and the strong magnetic block 2 39, the strong magnetic block 2 39 will adsorb the strong magnetic block 1 38, so that the strong magnetic block 2 39 limits the position of the ring frame 37 through the strong magnetic block 1 38, and the ring frame 37 limits the position of the floating block 36 through the sliding column 34, which is conducive to the floating block 36 to block the U-shaped tube 33. At the same time, it avoids the pipette touching the ring frame 37 during the process of collecting sodium hydroxide solution with the pipette gun, and the ring frame 37 pushes the sliding column 34 to drive the floating block 36 to move downward, resulting in the problem of loose sealing between the floating block 36 and the U-shaped tube 33.

[0033] See also Figure 1 - Figure 8 On the basis of the above embodiment, in another embodiment of the present invention, the gas injection device 4 includes an electric push rod 41 and a push plate 42. The electric push rod 41 is fixed at the bottom of the device body 1, and the push plate 42 is slidably installed inside the device body 1. The top of the telescopic end of the electric push rod 41 is fixedly connected to the bottom of the push plate 42. Through the setting of the above structure, the electric push rod 41 drives the push plate 42 to push the solvent inside the device body 1 to move upward. In this process, the hydrogen sulfide generated by the reaction in the device body 1 will be injected into the U-shaped tube 33, thereby improving the efficiency of collecting hydrogen sulfide into the measuring tube 31.

[0034] The gas injection device 4 also includes two rotating rods 43, two spiral blades 44, and four friction wheels 45. The two rotating rods 43 are rotatably installed on both sides of the top of the push plate 42 through brackets, and the two spiral blades 44 are respectively fixed on the middle outer walls of the two rotating rods 43. The four friction wheels 45 are respectively fixed on both ends of the two rotating rods 43. The outer walls of the friction wheels 45 are set as rough surfaces, and the inner walls of the device body 1 on both sides are set as rough surfaces. The rough surfaces of the friction wheels 45 are in contact with the rough surfaces of the device body 1. Through the setting of the above structure, the rotating rods 43 drive the spiral blades 44 to stir the cerebrospinal fluid and phosphoric acid in the device body 1. The stirring of the spiral blades 44 can increase the collision frequency of substances in the solution and promote the reaction. This helps to improve the reaction efficiency and complete the reaction in a shorter time.

[0035] An elliptical groove plate 46 is fixed to the outside of the rotating rod 43 on one side, a U-shaped frame 49 is fixed to the top of the push plate 42, a slide plate 410 is slidably installed on one side of the U-shaped frame 49, a plurality of moving rods 47 are penetrated and slidably installed on the top of the slide plate 410, a long float 411 is fixed to the top of the plurality of moving rods 47, and the two sides of the long float 411 are arranged in a triangular shape, and the triangular shape of the long float 411 is an inclined setting that decreases from the sampling device 2 to the direction of the measuring component 3, and an L-shaped connecting rod 48 is fixed to one end of the slide plate 410, and the L-shaped connecting rod 48 is fixed to the end of the slide plate 410. One end of the rod 48 away from the slide plate 410 is slidably connected to the inside of the elliptical groove plate 46, and the movable rod 47, the L-shaped connecting rod 48, and the U-shaped frame 49 are all retractable structures. Through the arrangement of the above structure, the reciprocating movement of the long float 411 can scrape the bubbles on the top of the inner wall of the device body 1, and under the guidance of the triangular inclined part of the long float 411, these bubbles move toward the direction of the U-shaped tube 33, thereby avoiding the problem of abnormal cerebrospinal fluid measurement caused by hydrogen sulfide bubbles being retained in the device body 1.

[0036] When the gas injection device 4 is in use, the electric push rod 41 is started, and the telescopic end of the electric push rod 41 pushes the push plate 42 to move upward along the inner wall of the device body 1, and the push plate 42 pushes the solvent inside the device body 1 to move upward. In this process, the hydrogen sulfide generated by the reaction in the device body 1 will be injected into the U-shaped tube 33, thereby improving the efficiency of collecting hydrogen sulfide into the measuring tube 31; at the same time, when the push plate 42 moves upward, the friction wheel 45 will be driven to move upward through the rotating rod 43. Under the action of the friction force between the friction wheel 45 and the inner wall of the device body 1, the friction wheel 45 will rotate during the movement, and the friction wheel 45 drives the rotating rod 43 to rotate, and the rotating rod 43 drives the spiral blade 44 to rotate, so that the spiral blade 44 stirs the cerebrospinal fluid and phosphoric acid in the device body 1. The stirring of the spiral blade 44 can increase the collision frequency of substances in the solution and promote the reaction, which helps to improve the reaction efficiency and complete the reaction in a shorter time; at the same time, the long float 411 is affected by the buoyancy of the solvent inside the device body 1, and the long float 411 will float on the device body 1, during which the long float 411 drives the moving rod 47 to move upward, and when the rotating rod 43 rotates, the elliptical groove plate 46 is driven to rotate, and the elliptical groove plate 46 drives the L-shaped connecting rod 48 to drive the slide plate 410 to move back and forth along the outer wall of the U-shaped frame 49, and the U-shaped frame 49 drives the long float 411 to move back and forth through the moving rod 47. When the push plate 42 pushes the solvent inside the device body 1 to the top position of the inner wall of the device body 1, the long float 411 immediately contacts the top of the inner wall of the device body 1 and reverses in the device body 1. During the process of injecting the generated hydrogen sulfide into the U-shaped tube 33, some bubbles will remain on the top of the inner wall of the device main body 1. These bubbles will contain some hydrogen sulfide that cannot be injected into the U-shaped tube 33. At this time, the reciprocating movement of the long float 411 can scrape the bubbles on the top of the inner wall of the device main body 1, and under the guidance of the triangular inclined part of the long float 411, these bubbles move toward the direction of the U-shaped tube 33, thereby avoiding the problem of abnormal cerebrospinal fluid measurement caused by the retention of hydrogen sulfide bubbles in the device main body 1.

[0037] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A cerebrospinal fluid sampling and detection device for neurology, comprising a device body (1), characterized in that: A sampling device (2) is provided on one side of the device body (1), a measuring assembly (3) for measuring the hydrogen sulfide content is provided on the top of the device body (1), and a gas injection device (4) for injecting hydrogen sulfide gas into the measuring assembly (3) is provided inside the device body (1); The sampling device (2) comprises a cross frame (21), wherein the cross frame (21) is fixed to the bottom of the device body (1), a liquid storage tube (22) is fixed to one end of the cross frame (21) away from the device body (1), and the liquid storage tube (22) is arranged in an inclined state, a hollow plug rod (23) is slidably mounted inside the liquid storage tube (22), and a one-way liquid inlet tube (24) is fixed inside the hollow plug rod (23), an exhaust pipe (25) is fixed to the top of the liquid storage tube (22), a floating ball (26) is arranged inside the liquid storage tube (22), and the liquid storage tube (22) is connected to the device body (1) via a connecting tube (28), and an opening and closing valve (27) is arranged in the middle of the connecting tube (28); The float ball (26) is located on a side of the hollow plug rod (23) close to the device body (1), and a circular cavity for accommodating the float ball (26) is provided at the bottom of the exhaust pipe (25); The sampling device (2) comprises a trapezoidal protruding disk (29) and a trapezoidal concave disk (210), wherein the trapezoidal protruding disk (29) is fixed to a side of the hollow plug rod (23) close to the device body (1), and the trapezoidal concave disk (210) is fixed to a side of the inner wall of the liquid storage tube (22), and the trapezoidal protruding disk (29) and the trapezoidal concave disk (210) are arranged opposite to each other; The measuring assembly (3) comprises a measuring cylinder (31), a cylinder cover (32), a plug disc (35), a ring frame (37), four U-shaped tubes (33), four sliding columns (34), and four floating blocks (36). The measuring cylinder (31) is fixed to the top of the device body (1); the cylinder cover (32) is threadedly connected to the top of the measuring cylinder (31); the plug disc (35) is fixed to the lower inner wall of the measuring cylinder (31); one end of the four U-shaped tubes (33) is uniformly penetrated and fixed to the top of the plug disc (35); the other ends of the four U-shaped tubes (33) are located inside the measuring cylinder (31); the four sliding columns (34) are uniformly penetrated and slidably installed on the top of one side of the four U-shaped tubes (33) close to the plug disc (35); the ring frame (37) is fixed between the tops of the four sliding columns (34); and the four floating blocks (36) are fixed to the bottoms of the four sliding columns (34).

2. A cerebrospinal fluid sampling and detection device for neurology according to claim 1, characterized in that: A liquid inlet pipe is fixed on the top of the device body (1), a liquid discharge pipe is fixed on the side of the device body (1), and a valve is arranged in the middle of the liquid discharge pipe.

3. A cerebrospinal fluid sampling and detection device for neurology according to claim 2, characterized in that: The measuring assembly (3) further comprises four strong magnetic blocks (38), four strong magnetic blocks (39), and four fixing frames (310). The four strong magnetic blocks (38) are respectively fixed at the four corners of the top of the ring frame (37). The four fixing frames (310) are respectively fixed at the upper inner wall of the measuring tube (31) in a uniform manner around the circumference. The four strong magnetic blocks (39) are respectively fixed at the bottom of the four fixing frames (310).

4. A cerebrospinal fluid sampling and detection device for neurology according to claim 3, characterized in that: The strong magnetic block 1 (38) and the strong magnetic block 2 (39) are arranged relative to each other, and the magnetic forces of the strong magnetic block 1 (38) and the strong magnetic block 2 (39) attract each other.

5. The cerebrospinal fluid sampling and detection device for neurology according to claim 1, characterized in that: The gas injection device (4) comprises an electric push rod (41) and a push plate (42); the electric push rod (41) is fixed to the bottom of the device body (1); the push plate (42) is slidably mounted inside the device body (1); and the top of the telescopic end of the electric push rod (41) is fixedly connected to the bottom of the push plate (42).

6. A cerebrospinal fluid sampling and detection device for neurology according to claim 5, characterized in that: The gas injection device (4) further comprises two rotating rods (43), two spiral blades (44), and four friction wheels (45); the two rotating rods (43) are rotatably mounted on both sides of the top of the push plate (42) through brackets; the two spiral blades (44) are respectively fixed to the middle outer walls of the two rotating rods (43); the four friction wheels (45) are respectively fixed to both ends of the two rotating rods (43); the outer walls of the friction wheels (45) are rough surfaces; the inner walls of the device body (1) are rough surfaces on both sides; and the rough surfaces of the friction wheels (45) are in contact with the rough surfaces of the device body (1).

7. A cerebrospinal fluid sampling and detection device for neurology according to claim 6, characterized in that: An elliptical groove disk (46) is fixed to the outside of the rotating rod (43) on one side, a U-shaped frame (49) is fixed to the top of the push plate (42), a slide plate (410) is slidably mounted on one side of the U-shaped frame (49), a plurality of moving rods (47) are penetrated and slidably mounted on the top of the slide plate (410), long floats (411) are fixed to the tops of the plurality of moving rods (47), and the two sides of the long floats (411) are arranged in a triangular shape, the triangular shape of the long floats (411) is arranged to be inclined in a decreasing direction from the sampling device (2) to the measuring component (3), an L-shaped connecting rod (48) is fixed to one end of the slide plate (410), and the end of the L-shaped connecting rod (48) away from the slide plate (410) is slidably connected to the inside of the elliptical groove disk (46), and the moving rods (47), the L-shaped connecting rod (48) and the U-shaped frame (49) are all arranged in a telescopic structure.

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