Optical fiber push needle for radioactive particle implantation gun

Abstract

The invention discloses an optical fiber push needle for a radioactive particle implantation gun, and belongs to the field of close-range radiotherapy. The problems that the space dose distribution of the particle source is inaccurate and an intraoperative in-vivo close-range dose measurement tool is lacked are solved. The optical fiber radiation sensor is characterized in that the optical fiber radiation sensor comprises an adjustable sleeve and an optical fiber radiation sensor inner core (3), the adjustable sleeve comprises an outer shell (1) and an inner cylinder (2) which are arranged in a sleeved mode, the optical fiber radiation sensor inner core (3) is fixedly sealed in the inner cylinder (2), and a radiation sensitive probe (8) is arranged at the front end of the optical fiber radiation sensor inner core (3). The method is used for implantation of near-distance radiotherapy particles and intraoperative in-vivo real-time dose monitoring, an effective way is provided for in-vivo dose monitoring in near-distance radiotherapy, and the accuracy of radioactive particle implantation positions and dose distribution is guaranteed.

Description

Technical Field

[0001] The invention relates to an optical fiber push pin of an implantation gun, in particular to an optical fiber push pin used for a radioactive particle implantation gun, and belongs to the field of close-range radiotherapy. Background Art

[0002] Cancer treatment has always been a problem that has troubled all of humanity. In particular, the incidence of cancer has continued to rise in recent years. Generally speaking, surgical resection is the best option for treating malignant tumors. For patients with advanced cancer who cannot undergo surgery to remove the tumor or who are in very poor physical condition, radiotherapy and chemotherapy are the first choice. Compared with whole-body external beam radiotherapy, the minimally invasive interventional brachytherapy that has been gradually applied in recent years has shown its unique advantages. It generally involves implanting radioactive particles into tumor tissue or near the tumor through minimally invasive surgery under the guidance of CT images, thereby directly inhibiting or killing cancer cells in the human body. The minimally invasive surgical process and the fixed-point directional radiation of the radioactive source can not only ensure the patient's rapid recovery after surgery, but also protect the patient's healthy tissues from radiation to the greatest extent, which can greatly improve the patient's treatment prognosis.

[0003] The current brachytherapy technology is not very mature, and it is usually used only as a palliative treatment in clinical practice. From the follow-up survey results of the treatment prognosis of many brachytherapy patients, it can be concluded that the main factors restricting it are the inaccurate spatial dose distribution of the particle source and the lack of intraoperative in vivo brachytherapy measurement tools. Summary of the invention

[0004] In order to overcome the problems of inaccurate spatial dose distribution of the above-mentioned particle source and lack of intraoperative close-range dose measurement tools in vivo, the present invention provides an optical fiber push pin for a radioactive particle implantation gun. A brief overview of the present invention is given below to provide a basic understanding of certain aspects of the present invention. It should be understood that this overview is not an exhaustive overview of the present invention. It is not intended to determine the key or important parts of the present invention, nor is it intended to limit the scope of the present invention.

[0005] The technical solution of the present invention:

[0006] The invention discloses an optical fiber push pin for a radioactive particle implantation gun, comprising an adjustable sleeve and an optical fiber radiation sensor inner core. The adjustable sleeve comprises an outer shell and an inner cylinder which are arranged in a set manner. The optical fiber radiation sensor inner core is sealed in the inner cylinder. A radiation sensitive probe is arranged at the front end of the optical fiber radiation sensor inner core.

[0007] As a further improvement of the present invention, the front end of the fiber optic radiation sensor core is connected to the catheter of the particle gun, and a set screw is provided on the catheter; the tail end of the fiber optic radiation sensor core is led out from the inner tube and connected to a dose meter.

[0008] As a further improvement of the present invention, a fixing screw hole is opened on the outer shell, and a fixing bolt is connected in the fixing screw hole. The fixing bolt is used to limit the relative movement between the outer shell and the inner cylinder.

[0009] As a further improvement of the present invention, a push seat is provided at the rear end of the outer shell, a push handle is provided at the rear end of the inner tube, the outer shell and the inner tube are threadedly connected, and the extension of the inner tube relative to the outer shell is adjusted by screwing the push handle.

[0010] As a further improvement of the present invention, the push handle and the inner cylinder are both provided with distance scales.

[0011] As a further improvement of the present invention, the inner core of the optical fiber radiation sensor is fixedly packaged on the inner cylinder using epoxy resin glue, and the front end of the inner core of the optical fiber radiation sensor extends 1 mm outside the inner cylinder.

[0012] As a further improvement of the present invention, the inner core of the optical fiber radiation sensor adopts PMMA optical fiber, and a radiation sensitive probe with radiation sensitive scintillation material embedded therein is arranged at the front end thereof.

[0013] As a further improvement of the present invention, the core diameter of the inner core of the optical fiber radiation sensor may be but is not limited to 0.5 mm.

[0014] As a further improvement of the present invention, the dose meter includes a main control MCU, a display module, an input module, a photomultiplier tube, an optical fiber interface, a power module and a wireless module. The display module, the input module and the photomultiplier tube are all connected to the main control MCU, the main control MCU is connected to the host computer through the wireless module, the photomultiplier tube is connected to the inner core of the optical fiber radiation sensor through the optical fiber interface, and the power module supplies power to the dose meter.

[0015] As a further improvement of the present invention, the fixing bolt and the set screw are both made of hard rubber material.

[0016] The beneficial effects of the present invention are embodied in:

[0017] Compared with the prior art, the present invention designs a fiber optic push pin for a radioactive particle implantation gun, which is used for implantation of close-range radiotherapy particles and real-time in vivo dose monitoring during surgery. The adjustable sleeve-type push pin structure of the present invention not only effectively ensures the stable implantation of particles, but also can adjust the elongation of the inner cylinder after implantation to control the dose measured at different positions; the inner core of the fiber optic radiation sensor sealed in the inner cylinder of the present invention is a novel fiber optic scintillation detector with excellent spatial position resolution and good low-dose sensitivity, which can be used for dose measurement of close-range radiotherapy particles, providing an effective way for in vivo dose monitoring during close-range radiotherapy, and ensuring the accuracy of radioactive particle implantation position and dose distribution; the threaded connection between the outer shell and the inner cylinder of the present invention, as well as the push handle and the inner cylinder with scales, ensure the precise adjustment of the elongation of the inner cylinder; the dose measuring instrument of the present invention can display the measurement results of the fiber optic push pin in real time online, and is equipped with a main control MCU and a wireless communication module, which can transmit the on-site measurement results to the host computer in a wireless connection. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the structure of an optical fiber push pin used in a radioactive particle implantation gun;

[0019] Figure 2 This is a schematic diagram of implanting radioactive particles with a particle gun;

[0020] Figure 3 This is a schematic diagram of measuring local dose in the body with a particle gun;

[0021] Figure 4 This is a schematic diagram of the basic structure of a dose measuring instrument;

[0022] In the figure: 1-outer shell, 2-inner cylinder, 3-inner core of optical fiber radiation sensor, 4-push seat, 5-push handle, 6-fixing screw hole, 7-fixing bolt, 8-radiation sensitive probe, 9-particle gun, 10-optical fiber push pin, 11-fastening screw. DETAILED DESCRIPTION

[0023] In order to make the purpose, technical scheme and advantages of the present invention clearer, the present invention is described below by the specific embodiments shown in the accompanying drawings. However, it should be understood that these descriptions are exemplary only and are not intended to limit the scope of the present invention. In addition, in the following description, the description of known structures and technologies is omitted to avoid unnecessary confusion of the concept of the present invention. It should also be understood that, unless otherwise specified or indicated, the terms "first", "second", "third" and the like in the specification are only used to distinguish between the various components, elements, steps, etc. in the specification, rather than to represent the logical relationship or sequential relationship between the various components, elements, steps, etc.

[0024] Embodiment 1, combination Figure 1-Figure 4 To illustrate this embodiment, a fiber optic push pin for a radioactive particle implantation gun is provided. The fiber optic push pin 10 includes an adjustable sleeve and a fiber optic radiation sensor core 3. The adjustable sleeve includes an outer shell 1 and an inner cylinder 2 which are arranged in a suitable manner. The fiber optic radiation sensor core 3 is sealed in the inner cylinder 2, and a radiation sensitive probe 8 is arranged at the front end thereof.

[0025] This embodiment utilizes the miniaturization, bendability and long-distance transmission characteristics of the optical fiber sensor, and applies this embodiment to minimally invasive interventional surgery. It is used as a push needle of the particle gun 9 in radioactive particle implantation, and is used for dose measurement of brachytherapy particles. It provides an effective way to monitor the in vivo dose during brachytherapy, ensures the accuracy of the radioactive particle implantation position and dose distribution, and realizes real-time intraoperative intracavitary dose detection of brachytherapy.

[0026] It should be noted that: a push seat 4 is provided at the tail end of the outer shell 1, a push handle 5 is provided at the tail end of the inner cylinder 2, and the outer shell 1 and the inner cylinder 2 are connected by a threaded sleeve, and the extension of the inner cylinder 2 relative to the outer shell 1 is adjusted by screwing the push handle 5. The fiber optic radiation sensor core 3 passes through the push handle 5 on the inner cylinder 2, and can transmit the measurement signal over a long distance; the front end of the fiber optic radiation sensor core 3 is connected to the catheter of the particle gun 9, and a set screw 11 is provided on the catheter; the tail end of the fiber optic radiation sensor core 3 is led out from the inner cylinder 2 and connected to the dose measuring instrument, and the dose monitoring is realized through photoelectric conversion.

[0027] More specifically: the dose meter includes a main control MCU, a display module, an input module, a photomultiplier tube, an optical fiber interface, a power module and a wireless module. The display module, the input module and the photomultiplier tube are all connected to the main control MCU, the main control MCU is connected to the host computer through the wireless module, the photomultiplier tube is connected to the optical fiber radiation sensor core 3 through the optical fiber interface, and the power module supplies power to the dose meter. It has the functions of setting and changing initial parameters, real-time collection, display and storage of online data, wireless communication and data transmission.

[0028] More specifically, the outer shell 1 is provided with a fixing screw hole 6, and a fixing bolt 7 is connected in the fixing screw hole 6, and the fixing bolt 7 is used to limit the relative movement between the outer shell 1 and the inner tube 2. The push handle 5 and the inner tube 2 are both provided with distance scales for easy adjustment of the elongation.

[0029] It should be noted that, during the seed implantation process, the inner cylinder 2 and the outer shell 1 are usually fixed together to push the radioactive seeds, and at this time, the fixing bolt 7 needs to be inserted into the fixing screw hole 6 to limit the relative movement between the outer shell 1 and the inner cylinder 2. The fixing bolt 7 is made of hard rubber material to ensure that there is sufficient friction under a small pressure to limit the movement of the inner cylinder 2.

[0030] It should be pointed out that when using the optical fiber push pin 10 for in vivo dose monitoring, the outer shell 1 needs to be fixed on the particle gun 9, and then the fixing bolt 7 is unscrewed, and the extension of the inner cylinder 2 is controlled by rotating the push handle 5 so that the radiation sensitive probe 8 reaches the ideal position; the minimum division of the scale on the push handle 5 is 10μm; the limit of the extension of the inner cylinder 2 is 5cm.

[0031] More specifically: the optical fiber radiation sensor inner core 3 is fixedly packaged on the inner cylinder 2 using epoxy resin glue, and the front end of the optical fiber radiation sensor inner core 3 extends out of the inner cylinder 2 by 1 mm.

[0032] More specifically: the inner core 3 of the optical fiber radiation sensor is made of PMMA optical fiber, and a radiation sensitive probe 8 embedded with radiation sensitive scintillation material is arranged at the front end thereof.

[0033] It should be noted that the fiber optic radiation sensor core 3 has the natural advantages of miniaturization, flexibility and long-distance transmission, and the radiation sensitive probe 8 arranged at the front end thereof is embedded with a highly sensitive scintillation material to ensure sensitivity at low doses. The highly sensitive scintillation material can be, but is not limited to, Cd2O2S:Tb. For a fiber optic radiation sensor with a core diameter of 0.5 mm, its dose sensitivity can reach 701cps at 30μSv / h.

[0034] It should be noted that the optical fiber push pin 10 designed in the present invention is designed according to the particle gun 9 used in conjunction with it, and the diameter of its adjustable sleeve needs to be adapted to the inner diameter of the catheter of the particle gun 9. The optical fiber radiation sensor inner core 3 in the optical fiber push pin 10 also needs to match the diameter of the inner tube 2, and thus different optical fiber push pins 10 will exhibit different radiation dose sensitivities.

[0035] The present embodiment is a fiber optic push pin 10 for a radioactive particle implantation gun, which seals the inner core 3 of the fiber optic radiation sensor in the inner cylinder 2, and adds a real-time monitoring function of the intraoperative in vivo dose on the basis of ensuring the particle implantation function; wherein the threaded connection between the outer shell 1 and the inner cylinder 2 and the distance scale on the push handle 5 ensure the position diversity and accuracy of the dose monitoring point; the fixed screw hole 6 designed on the outer shell 1 limits the relative movement of the inner cylinder 2 during the particle implantation process, ensuring the most basic particle implantation effect of the particle gun 9.

[0036] Example 2: Based on Example 1, this example introduces in detail a detailed method for using an optical fiber push needle 10 used in a radioactive particle implantation gun during the particle implantation process and details to be noted, as follows:

[0037] like Figure 2 As shown, in this embodiment, an optical fiber push pin 10 for a radioactive particle implantation gun is used in the particle implantation process of a particle gun 9. Figure 2 A schematic structure of the particle gun 9 is given in FIG.

[0038] The fixing bolt 7 on the optical fiber push pin 10 is installed in the fixing screw hole 6 of the outer shell 1 to ensure that the inner cylinder 2 will not move relative to the outer shell 1 during the use of the push pin 10; the particle gun 9 catheter is also designed with a fixing screw hole and a matching fixing screw 11. During the particle implantation process, the fixing screw 11 is removed to ensure that the optical fiber push pin 10 can move freely in the catheter. During the particle implantation process, the complete process of using the optical fiber push pin 10 is to first remove the fixing screw 11 on the particle gun 9 catheter, then align the outer shell 1 of the optical fiber push pin 10 with the end face of the inner core 3 of the optical fiber radiation sensor and install the fixing bolt 7 on the outer shell 1 of the optical fiber push pin 10, then install the particle clip on the particle gun 9, and finally insert the optical fiber push pin 10 into the particle gun 9 catheter to push the radioactive particles into the body.

[0039] It is worth mentioning that before using the optical fiber push pin 10 to implant radioactive particles, it is necessary to ensure that the outer shell 1 is consistent with the end surface of the inner core 3 of the optical fiber radiation sensor in the inner tube 2, and it cannot exceed the outer shell 1 or shrink inside the outer shell 1. In addition, the set screw 11 on the particle gun 9 catheter is also made of hard rubber material to ensure greater friction.

[0040] It should be noted that after installing the fixing bolt 7 on the outer shell 1 of the optical fiber push pin 10, the operator needs to slightly twist the push handle 5 to determine whether the relative movement of the inner tube 2 is effectively restricted.

[0041] Example 3, based on Example 1, this example introduces in detail a detailed method for using an optical fiber push needle 10 for a radioactive particle implantation gun in the process of in vivo dose measurement and details to be noted, as follows:

[0042] like Figure 3 As shown, in this embodiment, an optical fiber push pin 10 for a radioactive particle implantation gun is used in an in vivo dose measurement process. Figure 3 A schematic structure of the particle gun 9 is given in FIG.

[0043] The fixing bolt 7 on the outer shell 1 of the optical fiber push pin 10 is removed to ensure that the extension of the inner cylinder 2 can be controlled by twisting the push handle 5 during use of the optical fiber push pin 10; the particle gun 9 catheter is also designed with a fixing screw hole and a matching fixing screw 11. During the in vivo dose measurement, the fixing screw 11 is installed in the fixing screw hole to ensure that the outer shell 1 of the optical fiber push pin 10 is fixed relative to the particle gun 9, so as to better control the precise movement of the inner cylinder 2 of the optical fiber push pin 10. During the in vivo dose measurement process, the complete use process of the optical fiber push pin 10 is first to withdraw the needle for a certain distance after the particles are implanted. The withdrawal distance depends on the required measurement position, usually withdrawing to 2-3cm from the required measurement point. Then install the fixing screw 11 on the particle gun 9 catheter to fix the position of the outer shell 1. Then remove the fixing bolt 7 on the outer shell 1 of the optical fiber push pin 10, and slowly twist the push handle 5 to control the inner cylinder 2 to extend out of the outer shell 1 to reach the required measurement position. Finally, read and record the measurement signal after photoelectric conversion.

[0044] It is worth mentioning that the current extension of the inner cylinder 2 can be read through the scale on the push handle 5 and the inner cylinder 2. If it is a dose measurement at a single position, retract the extended inner cylinder 2 after the measurement is completed, then install the fixing screw 7 on the outer shell 1, then remove the set screw 11 on the particle gun 9 catheter, and finally take out the optical fiber push pin 10. If it is a dose measurement at multiple positions, first turn the push handle 5 to control the inner cylinder 2 to extend to the farthest point, then retract the inner cylinder 2 to each point in turn for measurement, and after the measurement is completed, use the same process to take out the optical fiber push pin 10.

[0045] It should be noted that when rotating the push handle 5 to control the extension of the inner tube 2, the speed should not be too fast to prevent the inner tube 2 from moving too much and stabbing the patient or touching the implanted particles.

[0046] The embodiments described above further illustrate the purpose, technical solutions and beneficial effects of the present application. It should be understood that the above description is only an embodiment of the present application and is not intended to limit the scope of protection of the present application. Any modifications, equivalent substitutions, improvements, etc. made on the basis of the technical solutions of the present application shall be included in the scope of protection of the present application.

Claims

1. An optical fiber push pin for a radioactive particle implantation gun, characterized in that: The invention comprises an adjustable sleeve and an optical fiber radiation sensor inner core (3), wherein the adjustable sleeve comprises an outer shell (1) and an inner cylinder (2) which are arranged in a sleeved manner, the optical fiber radiation sensor inner core (3) is sealed in the inner cylinder (2), and a radiation sensitive probe (8) is arranged at the front end of the optical fiber radiation sensor inner core (3).

2. The optical fiber push pin for a radioactive particle implantation gun according to claim 1, characterized in that: The front end of the optical fiber radiation sensor inner core (3) is connected to the catheter of the particle gun (9), and a set screw (11) is provided on the catheter; the rear end of the optical fiber radiation sensor inner core (3) is led out from the inner tube (2) and connected to a dose measuring instrument.

3. The optical fiber push pin for a radioactive particle implantation gun according to claim 2, characterized in that: The outer shell (1) is provided with a fixing screw hole (6), and a fixing bolt (7) is connected inside the fixing screw hole (6). The fixing bolt (7) is used to limit the relative movement between the outer shell (1) and the inner cylinder (2).

4. The optical fiber push pin for a radioactive seed implantation gun according to claim 1, characterized in that: The rear end of the outer shell (1) is provided with a push seat (4), and the rear end of the inner cylinder (2) is provided with a push handle (5). The outer shell (1) and the inner cylinder (2) are connected by a threaded sleeve, and the extension of the inner cylinder (2) relative to the outer shell (1) is adjusted by screwing the push handle (5).

5. The optical fiber push pin for a radioactive seed implantation gun according to claim 4, characterized in that: The push handle (5) and the inner cylinder (2) are both provided with distance scales.

6. The optical fiber push pin for a radioactive seed implantation gun according to claim 1, characterized in that: The optical fiber radiation sensor inner core (3) is fixedly packaged on the inner cylinder (2) using epoxy resin glue, and the front end of the optical fiber radiation sensor inner core (3) extends 1 mm outside the inner cylinder (2).

7. An optical fiber push pin for a radioactive seed implantation gun according to any one of claims 1 to 6, characterized in that: The inner core (3) of the optical fiber radiation sensor adopts a PMMA optical fiber, and a radiation sensitive probe (8) embedded with a radiation sensitive scintillation material is arranged at the front end thereof.

8. The optical fiber push pin for a radioactive seed implantation gun according to claim 1, characterized in that: The core diameter of the inner core (3) of the optical fiber radiation sensor is 0.5 mm.

9. The optical fiber push pin for a radioactive seed implantation gun according to claim 2, characterized in that: The dose measuring instrument comprises a main control MCU, a display module, an input module, a photomultiplier tube, an optical fiber interface, a power module and a wireless module. The display module, the input module and the photomultiplier tube are all connected to the main control MCU. The main control MCU is connected to a host computer via the wireless module. The photomultiplier tube is connected to an inner core (3) of an optical fiber radiation sensor via the optical fiber interface. The power module supplies power to the dose measuring instrument.

10. The optical fiber push pin for a radioactive seed implantation gun according to claim 3, characterized in that: The fixing bolts and the set screws are both made of hard rubber.

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