Traditional Chinese medicine formula for treating allergic rhinitis and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine formula for treating allergic rhinitis and a preparation method thereof, and relates to the technical field of traditional Chinese medicine formulas. The traditional Chinese medicine formula comprises the following components in parts by weight: 12-15 parts of astragalus membranaceus, 6-9 parts of ginger, 3-7 parts of fistular onion stalk, 5-8 parts of jujube, 8-12 parts of divaricate saposhnikovia root, 9-14 parts of bighead atractylodes rhizome, 10-12 parts of radix angelicae, 10-15 parts of liquorice, 6-10 parts of ligusticum wallichii, 5-8 parts of magnolia flower, 4-7 parts of mint, 6-11 parts of notopterygium root, 9-15 parts of purple perilla, 7-12 parts of platycodon grandiflorum and 12-15 parts of an anti-allergy mixture. According to the traditional Chinese medicine formula for treating allergic rhinitis and the preparation method of the traditional Chinese medicine formula, radix astragali and rhizoma atractylodis macrocephalae have the effects of tonifying qi and consolidating superficies, the body resistance can be enhanced, the exogenous evil resisting capacity of a human body is improved, and the attack frequency of the allergic rhinitis is reduced; divaricate saposhnikovia root, notopterygium root and purple perilla can dispel wind, relieve exterior syndrome, dispel wind evil and relieve symptoms such as rhinocnesmus and sneezing caused by rhinitis.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine formulas, in particular to a traditional Chinese medicine formula for treating allergic rhinitis and a preparation method thereof. Background Art

[0002] Allergic rhinitis is a non-infectious inflammatory disease of the nasal mucosa, which is mainly caused by the release of IgE-mediated mediators (mainly histamine) after an atopic individual comes into contact with an allergen, and involves a variety of immune-active cells and cytokines. The typical symptoms of allergic rhinitis are mainly paroxysmal sneezing, clear watery nasal discharge, nasal congestion and nasal itching, and some are accompanied by hyposmia. It manifests as paroxysmal sneezing several times a day, more than 3 times each time, mostly in the morning or at night or immediately after contact with allergens. It is also accompanied by a large amount of clear watery nasal discharge, which sometimes drips from the nostrils unconsciously. There are intermittent or continuous, unilateral or bilateral, and varying degrees of nasal congestion. The nasal mucosa is pale, the lower nails are edematous, and clear or sticky mucus can be seen in the common nasal passages and the nasal floor. Most patients have itchy noses, and patients with hay fever also have itchy eyes, ears, and throats. Allergic rhinitis is a global health problem that can lead to many diseases and loss of labor.

[0003] The Chinese patent with the publication number of CN102988615A discloses a Chinese medicine formula for treating allergic rhinitis, including the following components and the weight of each component is respectively: 10g of scutellaria, 10g of cinnamon twig, 5g of ephedra, 6g of angelica dahurica, 15g of magnolia, 15g of double flower, 10g of dandelion, 10g of physalis, 10g of saposhnikovia divaricata, 8g of cicada shell, and 5g of borneol; each component in the Chinese medicine formula described in the invention is a pure natural herbal ingredient, without hormones, no sensitization, no dependence, safe and reliable, therefore, it will not produce any toxic side effects on the human body, and the formula is simple, easy to take, low in cost, less pain for patients, and more importantly, the treatment of allergic rhinitis is effective and has a high cure rate. However, the Chinese medicine formula prepared by the above-mentioned prior art scheme cannot timely relieve the symptoms of sneezing, headache and the like caused by allergic rhinitis; for this reason, the present invention provides a Chinese medicine formula for treating allergic rhinitis and a preparation method thereof to solve the above problems. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a Chinese medicine formula for treating allergic rhinitis and a preparation method thereof, which solves the problems mentioned in the above background technology.

[0005] To achieve the above purpose, the present invention is implemented through the following technical scheme: a traditional Chinese medicine formula for treating allergic rhinitis, which comprises the following components in parts by weight: 12-15 parts of astragalus, 6-9 parts of ginger, 3-7 parts of scallion, 5-8 parts of jujube, 8-12 parts of siler, 9-14 parts of atractylodes, 10-12 parts of angelica, 10-15 parts of liquorice, 6-10 parts of chuanxiong, 5-8 parts of magnolia, 4-7 parts of mint, 6-11 parts of notopterygium, 9-15 parts of perilla, 7-12 parts of platycodon, and 12-15 parts of anti-allergic mixture.

[0006] Preferably, the anti-allergic mixture is composed of 35wt% to 55wt% of Bupleurum chinense, 25wt% to 35wt% of Schisandra chinensis, and 20wt% to 30wt% of Prunus mume.

[0007] Preferably, the Chinese medicine formula for treating allergic rhinitis also includes: 10-18 parts of roasted ephedra, 3-6 parts of asarum, and 8-15 parts of processed aconite.

[0008] Preferably, the Chinese medicine formula for treating allergic rhinitis specifically includes the following components in parts by weight: 13 parts of astragalus, 7 parts of ginger, 5 parts of scallion, 7 parts of jujube, 10 parts of siler, 11 parts of atractylodes, 11 parts of angelica, 12 parts of liquorice, 8 parts of chuanxiong, 6 parts of magnolia, 6 parts of mint, 8 parts of notopterygium, 12 parts of perilla, 10 parts of platycodon, 13 parts of anti-allergic mixture, 14 parts of roasted ephedra, 5 parts of asarum, and 12 parts of processed aconite.

[0009] Preferably, the traditional Chinese medicine formula for treating allergic rhinitis also includes: 6-10 parts of Ligusticum chuanxiong and 5-12 parts of Vitex rotundifolia.

[0010] Preferably, the Chinese medicine formula for treating allergic rhinitis specifically includes the following components in parts by weight: 13 parts of astragalus, 7 parts of ginger, 5 parts of scallion, 7 parts of jujube, 10 parts of siler, 11 parts of atractylodes, 11 parts of angelica, 12 parts of liquorice, 8 parts of chuanxiong, 6 parts of magnolia, 6 parts of mint, 8 parts of notopterygium, 12 parts of perilla, 10 parts of platycodon, 13 parts of anti-allergic mixture, 8 parts of ligusticum chuanxiong, and 10 parts of vitex rotundus.

[0011] Preferably, the Chinese medicine formula for treating allergic rhinitis also includes: 9-12 parts of Pseudostellaria heterophylla, 12-17 parts of Poria cocos, 12-18 parts of Dioscorea opposita, 10-15 parts of Lotus seeds, 10-12 parts of Lablab lentils, 6-10 parts of Amomum villosum, 12-20 parts of Coix seeds, 12-20 parts of Tangerine peel, and 9-12 parts of Cinnamon twigs.

[0012] Preferably, the Chinese medicine formula for treating allergic rhinitis specifically includes the following components in parts by weight: 13 parts of astragalus, 7 parts of ginger, 5 parts of scallion, 7 parts of jujube, 10 parts of siler, 11 parts of atractylodes, 11 parts of angelica, 12 parts of licorice, 8 parts of chuanxiong, 6 parts of magnolia, 6 parts of mint, 8 parts of notopterygium, 12 parts of perilla, 10 parts of platycodon, 13 parts of anti-allergic mixture, 10 parts of pseudostellaria, 15 parts of poria, 15 parts of yam, 13 parts of lotus seeds, 11 parts of white hyacinth bean, 8 parts of amomum, 16 parts of coix seed, 16 parts of tangerine peel, and 11 parts of cassia twig.

[0013] A method for preparing a traditional Chinese medicine formula for treating allergic rhinitis specifically comprises the following preparation steps: mixing the components in the traditional Chinese medicine formula according to the mass of each component, adding water and steaming, and using the generated steam to fumigate the nose for 20-30 minutes; wherein the amount of water added is twice that of the traditional Chinese medicine formula.

[0014] Beneficial Effects The present invention provides a Chinese medicine formula for treating allergic rhinitis and a preparation method thereof. Compared with the prior art, the Chinese medicine formula has the following beneficial effects: (1) The Chinese medicine formula for treating allergic rhinitis and its preparation method have the effects of tonifying qi and strengthening the exterior of the body by using Astragalus and Atractylodes macrocephala, which can enhance the body's resistance, improve the body's ability to resist external pathogens, and reduce the frequency of allergic rhinitis attacks; Saposhnikovia divaricata, Notopterygium wilfordii and Perilla frutescens can dispel wind and relieve exterior pathogens, dispel wind pathogens, and relieve symptoms such as nasal itching and sneezing caused by rhinitis; Ginger, Scallion White and Menthus fragrans can dispel wind and cold and help open the orifices; Magnolia officinalis, Angelica dahurica and Asarum can open the nasal orifices and relieve nasal congestion; Platycodon grandiflorum can clear the lungs and eliminate phlegm, which is beneficial to improving the symptoms caused by stagnation of lung qi; roasted Ephedra sinica can clear the lungs and relieve asthma, making breathing smoother; Jujube and Licorice can harmonize the various drugs and moderate the medicinal properties; Processed Aconite has the effect of warming yang and dispersing cold; Anti-allergic mixture has an anti-allergic effect; Chuanxiong has the effect of activating blood circulation and promoting qi circulation, improving the circulation of qi and blood.

[0015] (2) The Chinese medicine formula for treating allergic rhinitis and its preparation method, by adding Ligusticum chuanxiong and Vitex rotundus, makes the Chinese medicine formula have the effect of dispelling wind and relieving pain, which can relieve the discomfort such as headache caused by rhinitis, and reduce the symptoms of allergic rhinitis such as sneezing and runny nose caused by external wind and cold and other evil spirits.

[0016] (3) The Chinese medicine formula for treating allergic rhinitis and its preparation method, through the compounding of Radix Pseudostellariae, Poria, Chinese yam, lotus seed, white hyacinth bean, Amomum villosum, Coix seed, dried orange peel and cinnamon twig, can dispel wind-cold evil and relieve the symptoms of allergic rhinitis caused by exogenous wind-cold, such as relieving sneezing, runny nose, itchy nose and the like; at the same time, it can also enable the human body to better absorb the effective ingredients of the medicine. DETAILED DESCRIPTION

[0017] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0018] Example 1 A method for preparing a traditional Chinese medicine formula for treating allergic rhinitis, specifically comprising the following preparation steps: Step 1, weigh the raw materials: 12g of Astragalus, 6g of Ginger, 3g of Scallion, 5g of Jujube, 8g of Saposhnikovia, 9g of Atractylodes, 10g of Angelica Dahurica, 10g of Licorice, 6g of Chuanxiong, 5g of Magnolia, 4g of Menthus, 6g of Notopterygium, 9g of Perilla, 7g of Platycodon, 12g of Anti-allergic Mixture, 10g of Roasted Ephedra, 3g of Asarum, and 8g of Processed Aconite; The anti-allergic mixture is composed of 35wt% of bupleurum, 35wt% of schisandra, and 30wt% of ebony. Step 2: Mix the components of the Chinese medicine formula according to the mass of each component, add twice the amount of water as the Chinese medicine formula and boil, and use the generated steam to fumigate the nose for 20 minutes.

[0019] Example 2 A method for preparing a traditional Chinese medicine formula for treating allergic rhinitis, specifically comprising the following preparation steps: Step 1, weigh the raw materials: 15g of Astragalus, 9g of Ginger, 7g of Scallion, 8g of Jujube, 12g of Saposhnikovia, 14g of Atractylodes, 12g of Angelica Dahurica, 15g of Licorice, 10g of Chuanxiong, 8g of Magnolia, 7g of Menthus, 11g of Notopterygium, 15g of Perilla, 12g of Platycodon, 15g of Anti-allergic Mixture, 18g of Roasted Ephedra, 6g of Asarum, and 15g of Processed Aconite; The anti-allergic mixture is composed of 55wt% of bupleurum, 25wt% of schisandra, and 20wt% of ebony. Step 2: Mix the components of the Chinese medicine formula according to the mass of each component, add twice the amount of water as the Chinese medicine formula and boil, and use the generated steam to fumigate the nose for 20 minutes.

[0020] Example 3 A method for preparing a traditional Chinese medicine formula for treating allergic rhinitis, specifically comprising the following preparation steps: Step 1, weigh the raw materials: 12g of Astragalus, 6g of Ginger, 3g of Scallion, 5g of Jujube, 8g of Saposhnikovia, 9g of Atractylodes, 10g of Angelica Dahurica, 10g of Licorice, 6g of Chuanxiong, 5g of Magnolia, 4g of Menthus, 6g of Notopterygium, 9g of Perilla, 7g of Platycodon, 12g of Anti-allergic Mixture, 6g of Ligusticum chuanxiong, and 5g of Vitex rotundus. The anti-allergic mixture is composed of 40wt% of bupleurum, 30wt% of schisandra, and 30wt% of ebony. Step 2: Mix the components of the Chinese medicine formula according to the mass of each component, add twice the amount of water as the Chinese medicine formula and boil, and use the generated steam to fumigate the nose for 20-30 minutes.

[0021] Example 4 A method for preparing a traditional Chinese medicine formula for treating allergic rhinitis, specifically comprising the following preparation steps: Step 1, weigh the raw materials: 15g of Astragalus, 9g of Ginger, 7g of Scallion, 8g of Jujube, 12g of Saposhnikovia, 14g of Atractylodes, 12g of Angelica Dahurica, 15g of Licorice, 10g of Chuanxiong, 8g of Magnolia, 7g of Menthus, 11g of Notopterygium, 15g of Perilla, 12g of Platycodon, 15g of Anti-allergic Mixture, 10g of Ligusticum chuanxiong, and 12g of Vitex rotundus. The anti-allergic mixture is composed of 50wt% of bupleurum, 25wt% of schisandra, and 25wt% of ebony. Step 2: Mix the components of the Chinese medicine formula according to the mass of each component, add twice the amount of water as the Chinese medicine formula and boil, and use the generated steam to fumigate the nose for 30 minutes.

[0022] Example 5 A method for preparing a traditional Chinese medicine formula for treating allergic rhinitis, specifically comprising the following preparation steps: Step 1, weigh the raw materials: 12g of Astragalus, 6g of Ginger, 3g of Scallion, 5g of Jujube, 8g of Saposhnikovia, 9g of Atractylodes, 10g of Angelica Dahurica, 10g of Licorice, 6g of Chuanxiong, 5g of Magnolia, 4g of Menthus, 6g of Notopterygium, 9g of Perilla, 7g of Platycodon, 12g of Anti-allergic Mixture, 9g of Pseudostellariae, 12g of Poria, 12g of Chinese Yam, 10g of Lotus Seed, 10g of White Hyacinth Bean, 6g of Amomum, 12g of Coix Seed, 12g of Tangerine Peel, and 9g of Cinnamon Twig; The anti-allergic mixture is composed of 45wt% of bupleurum, 30wt% of schisandra, and 25wt% of ebony. Step 2: Mix the components of the Chinese medicine formula according to the mass of each component, add twice the amount of water as the Chinese medicine formula and boil, and use the generated steam to fumigate the nose for 25 minutes.

[0023] Example 6 A method for preparing a traditional Chinese medicine formula for treating allergic rhinitis, specifically comprising the following preparation steps: Step 1, weigh the raw materials: 15g of astragalus, 9g of ginger, 7g of scallion, 8g of jujube, 12g of siler, 14g of atractylodes, 12g of angelica, 15g of licorice, 10g of chuanxiong, 8g of magnolia, 7g of mint, 11g of notopterygium, 15g of perilla, 12g of platycodon, 15g of anti-allergic mixture, 12g of pseudoginseng, 17g of tuckahoe, 18g of yam, 15g of lotus seeds, 12g of white hyacinth bean, 10g of amomum, 20g of coix seed, 20g of tangerine peel, and 12g of cassia twig; The anti-allergic mixture is composed of 35wt% of bupleurum, 35wt% of schisandra, and 30wt% of ebony. Step 2: Mix the components of the Chinese medicine formula according to the mass of each component, add twice the amount of water as the Chinese medicine formula and boil, and use the generated steam to fumigate the nose for 30 minutes.

[0024] Typical clinical cases: Yang, female, 32 years old, technician, suffered from perennial allergic rhinitis, with symptoms of itchy nose, sneezing, runny nose, nasal congestion and shortness of breath. By using the composition of Example 1 or Example 2 of the present invention, 0.2g-0.3g was administered intranasally to the left and right nasal cavities three times a day, morning, noon and evening, for 10 days, the symptoms of allergic rhinitis were cured and there was no recurrence.

[0025] Zhang, female, 18 years old, student, seasonal allergic rhinitis, symptoms of which are allergic reactions to pollen in the spring season, usually manifested as nasal itching, sneezing, runny nose, nasal congestion accompanied by headache and stuffy head; by using the composition of Example 3 or Example 4 of the present invention, 0.1g-0.2g was administered intranasally to the left and right nasal cavities three times a day, morning, noon and evening, for 5 days, the symptoms of allergic rhinitis were significantly improved, and there was no recurrence in the spring of the following years.

[0026] Xu, male, 27 years old, technician, suffered from perennial allergic rhinitis with symptoms of nasal itching, sneezing, and watery discharge. By using the composition of Example 5 or Example 6 of the present invention, 0.1g-0.2g was administered intranasally to the left and right nasal cavities three times a day, morning, noon, and evening, for 10 days, the symptoms related to allergic rhinitis were cured and there was no recurrence.

[0027] Meanwhile, the contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0028] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0029] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A Chinese medicine formula for treating allergic rhinitis, characterized in that: The Chinese medicine formula comprises the following components in parts by weight: 12-15 parts of astragalus, 6-9 parts of ginger, 3-7 parts of scallion, 5-8 parts of jujube, 8-12 parts of siler, 9-14 parts of atractylodes, 10-12 parts of angelica, 10-15 parts of liquorice, 6-10 parts of chuanxiong, 5-8 parts of magnolia, 4-7 parts of mint, 6-11 parts of notopterygium, 9-15 parts of perilla, 7-12 parts of platycodon, and 12-15 parts of anti-allergic mixture.

2. A Chinese medicine formula for treating allergic rhinitis according to claim 1, characterized in that: The anti-allergic mixture is composed of 35wt% to 55wt% of bupleurum, 25wt% to 35wt% of schisandra chinensis, and 20wt% to 30wt% of ebony.

3. A Chinese medicine formula for treating allergic rhinitis according to claim 1, characterized in that: The traditional Chinese medicine formula for treating allergic rhinitis also includes: 10-18 parts of roasted ephedra, 3-6 parts of asarum, and 8-15 parts of processed aconite.

4. A Chinese medicine formula for treating allergic rhinitis according to claim 3, characterized in that: The Chinese medicine formula for treating allergic rhinitis specifically comprises the following components in parts by weight: 13 parts of astragalus, 7 parts of ginger, 5 parts of scallion, 7 parts of jujube, 10 parts of siler, 11 parts of atractylodes, 11 parts of angelica, 12 parts of liquorice, 8 parts of chuanxiong, 6 parts of magnolia, 6 parts of mint, 8 parts of notopterygium, 12 parts of perilla, 10 parts of platycodon, 13 parts of anti-allergic mixture, 14 parts of roasted ephedra, 5 parts of asarum, and 12 parts of processed aconite.

5. A Chinese medicine formula for treating allergic rhinitis according to claim 1, characterized in that: The traditional Chinese medicine formula for treating allergic rhinitis also includes 6 to 10 portions of Ligusticum chuanxiong and 5 to 12 portions of Vitex rotundifolia.

6. A Chinese medicine formula for treating allergic rhinitis according to claim 5, characterized in that: The Chinese medicine formula for treating allergic rhinitis specifically comprises the following components in parts by weight: 13 parts of astragalus, 7 parts of ginger, 5 parts of scallion, 7 parts of jujube, 10 parts of siler, 11 parts of atractylodes, 11 parts of angelica, 12 parts of liquorice, 8 parts of chuanxiong, 6 parts of magnolia, 6 parts of mint, 8 parts of notopterygium, 12 parts of perilla, 10 parts of platycodon, 13 parts of anti-allergic mixture, 8 parts of ligusticum chuanxiong, and 10 parts of vitex rotundus.

7. A Chinese medicine formula for treating allergic rhinitis according to claim 1, characterized in that: The traditional Chinese medicine formula for treating allergic rhinitis also includes: 9-12 parts of Pseudostellaria heterophylla, 12-17 parts of Poria cocos, 12-18 parts of Chinese yam, 10-15 parts of lotus seeds, 10-12 parts of white hyacinth bean, 6-10 parts of Amomum villosum, 12-20 parts of Coix seeds, 12-20 parts of dried tangerine peel, and 9-12 parts of cassia twig.

8. A Chinese medicine formula for treating allergic rhinitis according to claim 7, characterized in that: The Chinese medicine formula for treating allergic rhinitis specifically comprises the following components in parts by weight: 13 parts of astragalus, 7 parts of ginger, 5 parts of scallion, 7 parts of jujube, 10 parts of siler, 11 parts of atractylodes, 11 parts of angelica, 12 parts of liquorice, 8 parts of chuanxiong, 6 parts of magnolia, 6 parts of mint, 8 parts of notopterygium, 12 parts of perilla, 10 parts of platycodon, 13 parts of anti-allergic mixture, 10 parts of pseudostellaria, 15 parts of tuckahoe, 15 parts of yam, 13 parts of lotus seeds, 11 parts of white hyacinth bean, 8 parts of amomum, 16 parts of coix seeds, 16 parts of tangerine peel, and 11 parts of cassia twig.

9. A method for preparing a traditional Chinese medicine formula for treating allergic rhinitis according to any one of claims 1 to 8, characterized in that: The method specifically comprises the following preparation steps: mixing the components in the traditional Chinese medicine formula according to the weight of each component, adding water and steaming, and using the generated steam to fumigate the nose for 20-30 minutes; wherein the amount of water added is twice that of the traditional Chinese medicine formula.