A kind of insecticide composition containing benzoylurea

Abstract

The present invention belongs to the field of pesticides and insecticides and relates to an insecticidal composition containing a benzoylurea. The insecticidal composition comprises active ingredients A and B, wherein active ingredient A is a compound of formula (I) and active ingredient B is a benzoylurea compound. The mass ratio of active ingredient A to active ingredient B is 1:50 to 56:1. The insecticidal composition of the present invention has the advantages of enhancing synergy and delaying resistance development, and is used for controlling resistant pests.

Description

Technical Field

[0001] The invention belongs to the technical field of pesticides and insecticides, and particularly relates to an insecticide composition containing benzoylureas. Background Art

[0002] Benzoylurea insecticides are a class of chitin synthesis inhibitors, primarily benzoylurea compounds. They act as insect growth regulators by inhibiting the activity of chitin synthase in target pests, affecting chitin synthesis in the cuticle. This in turn affects the insects' feeding, molting, and pupation, ultimately leading to their death. These insecticides offer advantages such as high selectivity and easy decomposition in the environment, providing good control against Lepidoptera and Diptera pests. However, they are not fast-acting and are prone to developing resistance.

[0003] In agricultural production, the frequent and irrational use of pesticides has led to the continuous development of insect resistance, which has caused more severe damage to crops and made prevention and control more difficult. To promote the sustainable development of benzoylurea pesticides and address the scientific challenges they face, this study combined the compound of formula (I) with a benzoylurea pesticide to achieve rapid and simultaneous control of different pests, expanding the control spectrum, improving the efficacy of the pesticide, and mitigating the development of pest resistance. Summary of the Invention

[0004] The present invention aims to provide an insecticide composition containing benzoylureas which has synergistic effects, reduces resistance and has low use cost.

[0005] To achieve the above object, the technical solution adopted by the present invention is: an insecticide composition containing benzoylurea, comprising active ingredient A and active ingredient B, wherein the active ingredient A is a compound of formula (I) with the following structure:

[0006] The active ingredient B is a benzoylurea compound;

[0007] Furthermore, the benzoylurea compounds include lufenuron, diflubenzuron, diflubenzuron, bistrifluan, chlorfluazuron, fluazifop, flufenoxuron, flubendiamide, flufenoxuron, flubendiamide, triflumuron, noviflumuron, and hexaflumuron;

[0008] Furthermore, the benzoylurea compound is diflubenzuron, triflumuron, and hexaflumuron;

[0009] Furthermore, the mass ratio between the active ingredient A and the active ingredient B is 1:50 to 56:1;

[0010] Furthermore, the mass ratio between the active ingredient A and the active ingredient B is 1:35 to 35:1;

[0011] Furthermore, the mass ratio of the compound of formula (I) to diflubenzuron is 1:35 to 35:1, such as 1:35, 1:18, 1:9, 2:5, 3:4, 9:1, 18:1, 35:1 or any value between the above values;

[0012] Furthermore, the mass ratio of the compound of formula (I) to diflubenzuron is 1:18 to 18:1.

[0013] Furthermore, the mass ratio of the compound of formula (I) to diflubenzuron is 1:18, 1:9, 2:5, 3:4, 9:1, 18:1;

[0014] Furthermore, the mass ratio of the compound of formula (I) to triflumuron is 1:32 to 27:1, such as 1:32, 1:7, 4:1, 4:5, 12:1, 27:1 or any value between the above values;

[0015] Furthermore, the mass ratio of the compound of formula (I) to triflumuron is 1:7 to 27:1,

[0016] Furthermore, the mass ratio of the compound of formula (I) to triflumuron is 1:7, 4:1, 4:5, 12:1, 27:1;

[0017] The mass ratio of the compound of formula (I) to hexaflumuron is 1:27 to 27:1; such as 1:27, 1:14, 1:6, 2:3, 6:1, 14:1, 27:1, 56:1 or any value between the above values;

[0018] Furthermore, the mass ratio of the compound of formula (I) to hexaflumuron is 1:14 to 27:1;

[0019] Furthermore, the mass ratio of the compound of formula (I) to hexaflumuron is 1:14, 1:6, 2:3, 6:1, 14:1, 27:1;

[0020] Furthermore, based on the total mass of the insecticide composition being 100 wt%, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 0.5% to 90%;

[0021] Furthermore, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 1% to 85%;

[0022] Furthermore, the insecticide composition further comprises, in addition to the active ingredient, agriculturally acceptable auxiliary ingredients, wherein the auxiliary ingredients are selected from one or more of a wetting agent, a dispersant, an emulsifier, a thickener, a disintegrant, an antifreeze agent, a defoaming agent, a solvent, a preservative, a stabilizer, a synergist or a carrier;

[0023] Furthermore, the acaricidal composition further comprises an adjuvant, which is selected from one or more of a wetting agent, a dispersant, an emulsifier, a thickener, a disintegrant, an antifreeze agent, a defoaming agent, a solvent, a preservative, a stabilizer, a synergist and a carrier;

[0024] Furthermore, the wetting agent is selected from one or more of alkylbenzene sulfonate, alkylnaphthalene sulfonate, lignin sulfonate, sodium lauryl sulfate, sodium dioctyl sulfosuccinate, α-olefin sulfonate, alkylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, alkylphenol ethoxylate, fatty alcohol ethoxylate, fatty alcohol polyoxyethylene ether sodium sulfate, silkworm feces, soapberry powder, soapberry powder, SOPA, detergent, emulsifier 2000 series and wetting penetrant F; and / or

[0025] Furthermore, the dispersant is selected from one or more of lignin sulfonates, alkylnaphthalene sulfonate formaldehyde condensates, naphthalene sulfonates, tristyrylphenol ethoxylate phosphates, fatty alcohol ethoxylates, alkylphenol polyoxyethylene ethers, alkylphenol polyoxyethylene ether methyl ether condensate sulfates, fatty amine polyoxyethylene ethers, glycerol fatty acid ester polyoxyethylene ethers, polycarboxylates, polyacrylic acids, phosphates, EO-PO block copolymers and EO-PO graft copolymers; and / or

[0026] Furthermore, the emulsifier is selected from one or more of calcium dodecylbenzenesulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, phenylethylphenol polyoxyethylene polyoxypropylene ether, fatty alcohol ethylene oxide-propylene oxide copolymer, styrylphenol polyoxyethylene ether, castor oil polyoxyethylene ether and alkylphenol ether phosphate; and / or

[0027] Furthermore, the thickener is selected from one or more of xanthan gum, organobentonite, gum arabic, sodium alginate, magnesium aluminum silicate, carboxymethyl cellulose and white carbon black; and / or

[0028] Furthermore, the disintegrant is selected from one or more of sodium sulfate, ammonium sulfate, aluminum chloride, sodium chloride, ammonium chloride, bentonite, glucose, sucrose, starch, cellulose, urea, sodium carbonate, sodium bicarbonate, citric acid and tartaric acid; and / or

[0029] Furthermore, the antifreeze is selected from one or more of alcohols, alcohol ethers, chlorinated hydrocarbons and inorganic salts; and / or

[0030] Furthermore, the defoaming agent is selected from C 10 -C 20 Saturated fatty acid compounds, silicone oil, silicone compounds, C8-C 10 One or more of fatty alcohols; and / or

[0031] Furthermore, the solvent is selected from one or more of benzene, toluene, xylene, durene, methanol, ethanol, isopropanol, n-butanol, dimethyl sulfoxide, dimethylformamide, cyclohexanone, alkylene carbonate, diesel, solvent oil, vegetable oil, vegetable oil derivatives and water; and / or

[0032] Furthermore, the preservative is selected from one or more of propionic acid, sodium propionate, sorbic acid, sodium sorbate, potassium sorbate, benzoic acid, sodium benzoate, sodium p-hydroxybenzoate, methyl p-hydroxybenzoate, kasone and 1,2-benzisothiazolin-3-one; and / or

[0033] Furthermore, the stabilizer is selected from one or more of disodium hydrogen phosphate, oxalic acid, succinic acid, adipic acid, borax, 2,6-di-tert-butyl-p-cresol, triethanolamine oleate, epoxidized vegetable oil, kaolin, bentonite, attapulgite, white carbon black, talc, montmorillonite and starch; and / or

[0034] Furthermore, the synergist is selected from phosphine, piperonyl butoxide; and / or

[0035] Furthermore, the carrier is selected from one or more of ammonium salts, ground natural minerals, ground artificial minerals, silicates, resins, waxes, solid fertilizers, water, organic solvents, mineral oils, vegetable oils and vegetable oil derivatives.

[0036] Furthermore, the insecticide composition can be prepared into an agriculturally acceptable formulation, wherein the formulation is selected from a solid formulation and / or a liquid formulation;

[0037] Furthermore, the solid preparation includes powders, granules, pellets, tablets, strips, wettable powders, oil-dispersible powders, emulsion powders, water-dispersible granules, emulsion granules, water-dispersible tablets, soluble powders, soluble tablets or soluble granules;

[0038] Furthermore, the liquid preparation includes a soluble solution, a soluble gel, an oil, a film-spreading oil, an emulsifiable concentrate, a latex, a dispersible liquid, an ointment, an aqueous emulsion, an oil emulsion, a microemulsion, a fat, a suspension, a microcapsule suspension, an oil suspension, a dispersible oil suspension, a suspoemulsion, a microcapsule suspension-suspension, a microcapsule suspension-water emulsion or a microcapsule suspension-suspoemulsion;

[0039] Furthermore, the solid preparation is selected from wettable powders and water-dispersible granules; the liquid preparation is selected from emulsifiable concentrates, aqueous emulsions, microemulsions, suspensions, suspoemulsions, and dispersible oil suspensions;

[0040] Furthermore, the solid preparation is selected from wettable powders and water dispersible granules; the liquid preparation is selected from emulsifiable concentrates and suspension concentrates;

[0041] Application of the insecticide composition of the present invention in preventing and controlling agricultural and forestry pests and sanitary pests;

[0042] The insecticide composition of the present invention can be used to control pests on fruit trees, vegetables, ornamental plants, tea, cotton, and cereal crops;

[0043] Furthermore, the agricultural and forestry pests and sanitary pests are Lepidoptera pests;

[0044] Furthermore, the Lepidoptera pests include: Adoxophyes spp., Adoxophyes orana, Agrotis spp. (cutworms), Agrotis ipsilon (black cutworm), Alabama argillacea (cotton leafworm), Amorbia cuneana, Amyelosis transitella (navelorangeworm), Anacamptodes defectaria, Anarsia lineatella (peach twig borer), Anomis sabulifera (jute looper), Anticarsia g emma ta lis, Archips Argyrospila (fruittree leaf roller), Archips rosana (rose leaf roller), Argyrotaenia spp. (tortricid moths), Argyrotaenia citrana (orange tortrix), Autographa gamma, Bonagota cranaodes, Borbo cinnara (rice leaf folder), Bucculatrix thurberiella (cotton leaf perforator), Caloptilia spp. (leaf miners), Capua reticulana, Carposina niponensis (peach fruit moth), Chilo spp., Chlumetia transversa (mango shoot moth), borer), Choristoneura rosaceana (obliquebanded leafroller), Chrysodeixis spp.), Cnaphalocerus medinalis (grass leafroller), Colias spp., Conpomorpha cramerella, Cossus cossus (carpenter moth), Crambus spp. (sod webworms), Cydia funebrana (plum fruit moth), Cydia molesta (oriental fruit moth), Cydia nignicana (pea moth), Cydia pomonella (codling moth), Darna diducta, Diaphania spp. (stem borer), borers), Diatraea spp. (stalk borers), Diatraea saccharalis (sugarcane borer), Diatraea graniosella (southwester corn borer), Earias spp. (cotton bollworm), Earias insulata (Egyptian bollworm), Earias vitella (rough northern bollworm), Ecdytopopha aurantianum, Elasmopalpus lignosellus (lesser cornstalk borer), Epiphysias postruttana (light brown apple moth), Ephestia spp. (flour moths), Ephestia cautella) (almond moth), Ephestia elutella (tobbacomoth), Ephestia kuehniella (Mediterranean flour moth), Epimeces spp.), Epinotia aporema, Erionotathrax (banana skipper), Eupoecilia ambiguella (grapeberry moth), Euxoa auxiliaris (army cutworm), Feltia spp. (cutworms), Gortyna spp. (stemblerers), Grapholitamolesta (oriental fruit moth), Hedylepta indicate (beanleaf webber), Helicoverpa spp. (snowthr), Helicoverpa armigera, Helicoverpa zea, Heliothis spp., Heliothis budworm ( virescens), Hellula undalis (cabbage webworm), Indarbela spp. (root borers), Keiferia lycopersicella (tomato borer), Leucinodes orbonalis (eggplant borer), Leucoptera malifoliella (moth), Lithocollectis spp. (grape fruit moth), Lobesia botrana (grape fruit moth), Loxagrotis spp. (grape fruit moth), Loxagrotis albicosta (western bean cutworm), Lymantria dispar (gypsy moth), Lyonetia clerkella (apple leaf miner), Mahasena corbetti (oil palm bagworm), bagworm) and Malacosoma spp.) (tent caterpillars), Mamestra brassicae (cabbage armyworm), Maruca testulalis (bean pod borer), Metisa plana (bagworm), Mythimna unipuncta (true armyworm), Neoleucinodes elegantalis, Nymphula depunctalis (three-spotted water borer), Operophtherabrumata (winter looper), Ostrinia nubilalis (European corn borer), Oxydia vesulia, Pandemis cerasana (common currant tortrix), Pandemis heparana (brown apple tortrix), Papilio demodocus (African swallowtail), Pectinophora gossypiella (pink bollworm), (Bollworm), Peridroma species (pp.), Peridroma saucia (variegated cutworm), Perileucoptera coffeella (white coffee leafminer), Phthorimaea operculella (potato tuber moth), Phyllocnisitis citrella, Phyllonorycter spp., Pieris rapae, Plathypena scabra, Plodia interpunctella, Plutellaxylostella (diamondback moth), Polychrosis viteana (grapeberry moth), Prays endocarpa, Prays olive moth oleae) (olive moth), Pseudaletia spp.(spotworm), Spodoptera litura Fabricius, Pseudaletia unipunctata (armyworm), Pseudoplusia includes (, Rachiplusia nu), Chilo suppressalis (Walker), Scirpophaga incertulas, Sesamia spp. (stemborers), Sesamia inferens (pink rice stem borer), Spodoptera frugiperda (JESmmith), Sesamia nonagrioides, Setora nitens, Sitotroga cerealella (Angoumois grain moth), Sparganothis pilleriana, Spodoptera spp.), Spodoptera exigua, Spodoptera fugiperda, Spodoptera oridania (southern armyworm), Synanthedon spp., Thecla basilides, Thermisia gemmatalis, Tineola bisselliella (webbing clothesmoth), Trichoplusia ni (cabbage worm), Pierisrapae Linne (cabbage worm), and Tuta absoluta (tomato leafminer).

[0045] Furthermore, the lepidopteran pests include diamondback moth, beet armyworm, Spodoptera litura, fall armyworm, striped stem borer, cotton bollworm, and cabbage worm.

[0046] The present invention also provides a method for using the insecticidal composition containing benzoylureas, which comprises applying an effective dose of the composition to the pests to be controlled or the medium in which the pests grow.

[0047] The insecticide composition of the present invention has the following advantages:

[0048] 1) The insecticide composition of the present invention can produce a significant synergistic effect within a certain ratio range, thereby improving the toxicity and rapid effect of the agent;

[0049] 2) The insecticide composition of the present invention can delay the resistance of target pests and extend the service life of the product;

[0050] 3) The insecticide composition of the present invention expands the control spectrum while reducing the amount of pesticide used, thereby alleviating the pressure on the ecological environment and the cost of agricultural production. DETAILED DESCRIPTION

[0051] The present invention is further described below with reference to the examples. The percentages in the examples are all by weight, but the present invention is not limited thereto.

[0052] The composition of the present invention can be provided in the form of a formulation. It can be formulated as a suspension concentrate, emulsifiable concentrate, water-dispersible granules, aqueous emulsion, granules, wettable powder, or dispersible oil suspension, as needed. The content of the active ingredient in the composition of the present invention depends on the dosage when used alone, as well as the blending ratio and the degree of synergistic effect. The optimal range of the active ingredient content varies depending on the formulation type of the composition.

[0053] Formulation Examples

[0054] Preparation Example 1: 24% compound of formula (I)·diflubenzuron suspension (4:20)

[0055] Preparation formula: 4% compound of formula (I), 20% diflubenzuron, 5% sodium sulfate of fatty alcohol polyoxyethylene ether, 1.5% sodium salt of polycarboxylic acid, 3.5% styrenated phenol polyoxyethylene ether phosphate, 0.8% magnesium aluminum silicate, 0.2% xanthan gum, 0.5% sodium sorbate, 5% ethylene glycol, 0.5% organosilicon defoamer, and deionized water to make up the balance;

[0056] Preparation method: Add active ingredients to the wetting dispersant and defoamer, use zirconium oxide beads, and wet grind with a sand mill to D 90 (90% of the particles have a particle size of less than 10 μm) to obtain a crushed slurry. A thickener, antifreeze agent, preservative, etc. are added to the crushed slurry and mixed evenly. Deionized water is added to 100%, and the suspension product is obtained by high-speed shearing.

[0057] Preparation Example 2: 30% compound of formula (I)·thiofluanidone suspension (5:25)

[0058] Preparation formula: 5% compound of formula (I), 25% triflumuron, 2% fatty alcohol polyoxyethylene ether phosphate, 1% sodium polycarboxylate, 2.5% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 3.5% sodium lignin sulfonate, 0.8% magnesium aluminum silicate, 0.2% xanthan gum, 0.5% sodium sorbate, 4.5% propylene glycol, 0.5% silicone defoamer, and deionized water to make up the balance;

[0059] Preparation method: Same as Preparation Example 1.

[0060] Preparation Example 3: 6% compound of formula (I)·hexaflumuron emulsifiable concentrate (5:1)

[0061] Preparation formula: 5% compound of formula (I), 1% hexaflumuron, 10% propylene carbonate, 1.5% calcium dodecylbenzenesulfonate, 13.5% tristyrylphenol polyoxyethylene ether, 20% N,N-dimethylformamide, 2% soybean oil, 28% cyclohexanone, and methyl oleate makes up the balance;

[0062] Preparation method: first add the active ingredient into the solvent and dissolve it completely, then add the emulsifier and stir evenly to form a uniform and transparent oily liquid, and then fill it to prepare the emulsifiable concentrate preparation of the composition of the present invention.

[0063] Preparation Example 4: 4.5% compound of formula (I)·triflumuron emulsifiable concentrate (2:2.5)

[0064] Preparation formula: 2% compound of formula (I), 2.5% triflumuron, 10% propylene carbonate, 1.5% calcium dodecylbenzenesulfonate, 13.5% tristyrylphenol polyoxyethylene ether, 20% N,N-dimethylformamide, 0.5% BHT, 2.5% corn oil, 25% cyclohexanone, and methyl oleate makes up the balance;

[0065] Preparation method: Same as Preparation Example 3.

[0066] Preparation Example 5: 30% compound of formula (I)·diflubenzuron wettable powder (13:17)

[0067] Preparation formula: 13% compound of formula (I), 17% diflubenzuron, 8% naphthalenesulfonate formaldehyde condensate, 10% tea saponin, 2% sodium lauryl sulfate, 5% attapulgite, and kaolin makes up the balance;

[0068] Preparation method: The active ingredients, other functional additives and fillers are mixed according to the formula ratio, stirred evenly in a stirring kettle, and crushed and mixed evenly for multiple times in a jet mill to prepare the wettable powder of the composition of the present invention.

[0069] Preparation Example 6: 11% compound of formula (I)·hexaflumuron water dispersible granules (9.5:1.5)

[0070] Preparation formula: 9.5% compound of formula (I), 1.5% hexaflumuron, 7% sodium lignin sulfonate, 7% naphthalene sulfonate formaldehyde condensate, 2% sodium lauryl sulfate, 4.5% attapulgite, 20% starch, and kaolin to make up the balance;

[0071] Preparation method: According to the formula ratio of the embodiment, the active ingredient is added to the carrier, and the surfactant and other functional additives are added thereto, mixed, and after air flow grinding, 10-25% water is added, and then the water-dispersible granule product is obtained by kneading, granulating, drying and screening.

[0072] Indoor biological activity assay

[0073] Test basis: Refer to the agricultural industry standards "Guidelines for Indoor Bioassay Tests of Pesticides - Insecticides Part 6: Insect Dipping Method" (NY / T 1154.6-2006), "Guidelines for Indoor Bioassay Tests of Pesticides - Insecticides Part 7: Determination of Combined Action of Mixtures" (NY / T 1154.7-2006), "Guidelines for Indoor Bioassay Tests of Pesticides - Insecticides Part 14: Leaf Dipping Method" (NY / T1154.14-2008), etc.

[0074] Test target: beet armyworm;

[0075] Test method: Combination of leaf dipping method and insect dipping method;

[0076] Preparation of drugs: The test drugs were dissolved in acetone and prepared into 5 series of concentrations using 0.1% Tween 80 aqueous solution.

[0077] Test materials: Use a hole punch to punch leaf discs (1.5 cm in diameter) and immerse them in the drug solution for 10 seconds. After the solution is allowed to dry naturally, place the cabbage discs in a Petri dish lined with moisturizing filter paper. Place 20 third-instar larvae in the drug solution for 5 seconds. After absorbing the excess solution with filter paper, place the test insects in a Petri dish with leaves soaked in the corresponding concentration.

[0078] Experimental treatment: Each treatment was repeated 4 times, with a blank treatment as a control. The treated insects were reared in an artificial intelligence culture chamber at 25±1°C, a light intensity of L:D=16h:8h, and a relative humidity of 65%±5%.

[0079] Investigation method: After 72 hours, check the results. Use the tip of a brush to gently touch the insects. If there is no reaction, the insect is considered dead. Count the number of live and dead insects in each treatment and calculate the mortality rate.

[0080] Data statistics and analysis:

[0081] Based on the survey data, the adjusted mortality rate of each treatment was calculated.

[0082] The calculation results are retained to two decimal places:

[0083]

[0084] Where:

[0085] P——mortality rate, in percentage (%);

[0086] K——indicates the number of dead insects, the unit is head;

[0087] N——represents the total number of insects processed, in heads.

[0088]

[0089] Where:

[0090] P1——adjusted mortality rate, in percentage (%);

[0091] P t ——Treatment mortality rate, in percentage (%);

[0092] P0 - blank control mortality rate, in percentage (%).

[0093] If the control mortality rate is less than 5%, no correction is required; if the control mortality rate is between 5% and 20%, correction should be made; if the control mortality rate is greater than 20%, the test needs to be repeated.

[0094] The data were processed by probability value analysis method and analyzed by DPS statistical analysis system to obtain the toxicity regression line, LC 50 The activity of the test agents on the biological materials was evaluated by using the values, 95% confidence limits and correlation coefficient r.

[0095] The co-toxicity coefficient (CTC value) of the mixture is calculated as follows:

[0096]

[0097] Where:

[0098] ATI - measured toxicity index of mixture;

[0099] S——LC of standard pesticide 50 , the unit is milligrams per liter (mg / L);

[0100] M——LC of the mixture 50 , the unit is milligrams per liter (mg / L).

[0101] TTI=TI A * P A +TI B * P B

[0102] Where:

[0103] TTI – Theoretical Toxicity Index of Mixtures;

[0104] TI A ——Agent toxicity index;

[0105] P A ——The percentage of agent A in the mixture, in percentage (%);

[0106] TI B ——Toxicity index of agent B;

[0107] P B ——The percentage of agent B in the mixture, in percentage (%).

[0108]

[0109] Where:

[0110] CTC – Co-toxicity coefficient;

[0111] ATI - measured toxicity index of mixture;

[0112] TTI - Theoretical Toxicity Index of Mixture.

[0113] A co-toxicity coefficient (CTC) of 120 or higher indicates a synergistic effect; a co-toxicity coefficient (CTC) of 80 or lower indicates an antagonistic effect; and a co-toxicity coefficient (CTC) of 80 or lower indicates an additive effect.

[0114] Test results:

[0115] Combined toxicity of the mixture to Spodoptera exigua: LC of the compound of formula (I) against Spodoptera exigua 50 The concentration of the compound of formula (I) is 6.11 mg / L. The mixture of compound of formula (I) with diflubenzuron, triflumuron and hexaflumuron has a good combined effect on Spodoptera exigua, and at a certain mass ratio, it shows obvious synergistic effect.

[0116] The results in Table 1 show that when the weight ratio of the compound of formula (I) and diflubenzuron to the beet armyworm is 1:35 to 35:1, the co-toxicity coefficient is greater than 120, and the mixture of the two exhibits a synergistic effect within this weight ratio range; when the weight ratio of the compound of formula (I) and diflubenzuron to the beet armyworm is 1:18 to 18:1, the co-toxicity coefficient is greater than 150, which has an obvious synergistic effect.

[0117] Table 1 Toxicity test results of different ratios of compound of formula (I) and diflubenzuron against Spodoptera exigua

[0118]

[0119] The results in Table 2 show that when the weight ratio of the compound of formula (I) and cyfluthrin to beet armyworm is 1:50 to 27:1, the co-toxicity coefficient is greater than 80, and the mixture of the two shows an additive or synergistic effect within this weight ratio range; when the weight ratio of the compound of formula (I) and cyfluthrin to beet armyworm is 1:32 to 27:1, the co-toxicity coefficient is greater than 120, which has an obvious synergistic effect.

[0120] Table 2 Toxicity test results of different ratios of compound of formula (I) and triflumuron against Spodoptera exigua

[0121]

[0122]

[0123] The results in Table 3 show that when the weight ratio of the compound of formula (I) and hexaflumuron to the beet armyworm is 1:27 to 56:1, the co-toxicity coefficient is greater than 80, and the mixture of the two shows an additive or synergistic effect within this weight ratio range; when the weight ratio of the compound of formula (I) and hexaflumuron to the beet armyworm is 1:27 to 27:1, the co-toxicity coefficient is greater than 140, which has an obvious synergistic effect.

[0124] Table 3 Toxicity test results of different ratios of compound of formula (I) and hexaflumuron against Spodoptera exigua

[0125]

[0126] Field efficacy examples

[0127] Test crops and targets: green onion, beet armyworm;

[0128] Experimental location: Sunzhuang green onion field in Queshan County, Zhumadian City, Henan Province;

[0129] Application equipment: 3WBS-16 electric backpack sprayer;

[0130] Trial time: September 15, 2023;

[0131] Experimental environment: All experimental plots were cultivated under uniform conditions and adopted the same fertilizer and water management levels;

[0132] Test agent:

[0133] Table 4 Field test design and dosage

[0134]

[0135] Test method: Apply the pesticide once at the early stage of beet armyworm outbreak.

[0136] Plot area and repetition: random block arrangement, 20m per plot 2, each treatment was repeated 4 times.

[0137] Survey Methodology:

[0138] 1) Drug safety evaluation.

[0139] Observe the effects of the different pesticides on the growth of green onions 1, 3, 7, and 14 days after application, and record any pesticide damage. If any, record the type, severity, duration, and recovery of the damage.

[0140] 2) Investigation on prevention effectiveness.

[0141] Five random sampling points were taken in each plot, with 10 plants fixed at each point. The number of beet armyworms on all onion tubes of the whole plant was investigated. The base number of insects was investigated before spraying, and the number of remaining insects was investigated 3 days and 14 days after spraying.

[0142] Calculation formula and data analysis:

[0143]

[0144] Test results:

[0145] Safety: Visual observations at 1, 3, 7, and 14 days after application revealed that none of the pesticides used in this experiment caused any damage to the growth of green onions, indicating that the pesticides were safe under the experimental conditions.

[0146] Results of field efficacy test: As can be seen from Table 5, 3 days after application, 24% compound of formula (I)·carbamyl SC (4:20), 6% compound of formula (I)·hexaflumuron emulsifiable concentrate (5:1), and 30% compound of formula (I)·carbamyl SC (5:25) showed good quick-acting effect in controlling beet armyworm in onion fields, with control efficacies of 82.27%, 83.00%, and 80.01%, respectively. Each treatment was significantly higher than the control single agent.

[0147] Table 5 Field control effects of different pesticides on beet armyworm (3 days after application)

[0148]

[0149] Note: The above data are the average of 4 repetitions, and the values ​​are rounded to two decimal places. Different letters after the efficacy data in the same column indicate significant differences (P < 0.05).

[0150] As can be seen from Table 6, 14 days after application, 24% compound of formula (I)·carbamyl SC (4:20), 6% compound of formula (I)·hexaflumuron EC (5:1), and 30% compound of formula (I)·carbamyl SC (5:25) showed good sustained effectiveness in controlling beet armyworm in onion fields, with control efficacies of 87.74%, 90.81%, and 86.44%, respectively. Each treatment was significantly higher than the control single agent.

[0151] Table 6 Field control effect of the same pesticide on beet armyworm (14 days after application)

[0152]

[0153] Note: The above data are the average of 4 repetitions, and the values ​​are rounded to two decimal places. Different letters after the efficacy data in the same column indicate significant differences (P < 0.05).

[0154] The insecticide composition or formulation obtained by the present invention exhibits significant control efficacy, outperforming single agents in delaying the development of insecticide resistance and prolonging insecticide retention. Furthermore, no phytotoxicity was observed in the combined formulation on crops (scallions) during testing, demonstrating that the improved insecticide synergy of the resulting insecticide composition or formulation can reduce production and usage costs and is safe for crops.

[0155] Although the present invention has been described in detail above using general descriptions and specific implementation plans, it is obvious to those skilled in the art that some modifications or improvements can be made thereto based on the present invention. Therefore, these modifications or improvements made without departing from the spirit of the present invention shall fall within the scope of protection claimed by the present invention.

Claims

1. An insecticidal composition containing benzoylureas, characterized in that: The active ingredient A and the active ingredient B are included. The active ingredient A is a compound of formula (I) with the following structure: Formula (I), the active ingredient B is a benzoylurea compound, the benzoylurea compound is diflubenzuron, thiofluanid, and hexafluanid, the mass ratio of the compound of formula (I) to diflubenzuron is 1:35~35:1, the mass ratio of the compound of formula (I) to thiofluanid is 1:32~27:1, and the mass ratio of the compound of formula (I) to hexafluanid is 1:27~27:

1.

2. The insecticidal composition according to claim 1, wherein: The mass ratio of the compound of formula (I) to diflubenzuron is 1:18-18:1, the mass ratio of the compound of formula (I) to thiocarbamide is 1:7-27:1, and the mass ratio of the compound of formula (I) to hexaflumuron is 1:14-27:

1.

3. The insecticidal composition according to claim 2, wherein: The mass ratio of the compound of formula (I) to diflubenzuron is 1:18, 1:9, 2:5, 3:4, 9:1, and 18:1; the mass ratio of the compound of formula (I) to thiocarbamide is 1:7, 4:1, 4:5, 12:1, and 27:1; and the mass ratio of the compound of formula (I) to hexaflumuron is 1:14, 1:6, 2:3, 6:1, 14:1, and 27:

1.

4. The insecticidal composition according to claim 1, wherein: Based on the total mass of the insecticide composition being 100 wt%, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 1% to 85%.

5. The insecticidal composition according to claim 1, wherein: In addition to the active ingredients, the insecticide composition also includes agriculturally acceptable auxiliary ingredients, which are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoaming agents, solvents, preservatives, stabilizers, synergists or carriers.

6. The insecticidal composition according to claim 5, characterized in that: The insecticide composition is prepared into a formulation form permitted in agriculture, and the formulation form is a wettable powder, a water-dispersible granule, an emulsifiable concentrate, a suspension concentrate or a dispersible oil suspension concentrate.

7. Use of the insecticide composition according to any one of claims 1 to 6 for controlling agricultural and forestry pests and sanitary pests, characterized in that: The pest is beet armyworm.

8. The insecticidal composition according to claim 1, wherein: The insecticide composition is applied to the pests to be controlled or the medium where the pests grow at an effective dose.

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