A compound fresh bamboo traditional Chinese medicine composition for relieving cough and its application

Abstract

The present invention relates to the technical field of traditional Chinese medicine, and provides a compound fresh bamboo traditional Chinese medicine composition for relieving cough and its application. The traditional Chinese medicine formula is prepared from the following traditional Chinese medicines: 15-20 g of fresh bamboo, 15-20 g of astragalus membranaceus, 8-10 g of cinnamon twig, 6-10 g of trichosanthes kirilowii, 6-10 g of fritillaria cirrhosa, 6-10 g of raw pinellia ternata, 3-5 g of peucedanum praeruptorum, 3-5 g of mulberry bark, 3-5 g of licorice root, and 3-5 g of platycodon grandiflorum. The traditional Chinese medicine preparation of the present invention as a whole plays an all-round conditioning role for different types of coughs through various mechanisms such as clearing heat, moistening the lungs, warming yang, and resolving phlegm, and is particularly suitable for cough patients with spleen-stomach deficiency-cold complicated with phlegm-heat; the combination of the traditional Chinese medicines of the present invention can significantly improve the body weight of mice with spleen-stomach deficiency-cold, significantly prolong the cough latency of mice with spleen-stomach deficiency-cold, reduce the number of coughs of mice, and has a significant cough-relieving effect; at the same time, it can significantly increase the excretion amount of phenol red in the trachea of mice with spleen-stomach deficiency-cold, and has a significant phlegm-resolving effect.

Description

Technical Field

[0001] The present invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a compound fresh bamboo traditional Chinese medicine composition for relieving cough and its application. Background Art

[0002] Cough is one of the common symptoms of the respiratory system, usually caused by various factors such as exogenous wind-cold, wind-heat, and internal injury of phlegm-dampness. Traditional Chinese medicine has a long history in the field of relieving cough and resolving phlegm, and achieves the effect of relieving cough through various methods, such as different action mechanisms of clearing heat and resolving phlegm, warming the middle-jiao and dispelling cold, nourishing yin and moistening the lung. Commonly used single and compound traditional Chinese medicines have achieved good results in the treatment of cough, such as single herbs like Fritillaria cirrhosa, Licorice, and compound prescriptions like Qingfei Zhike Decoction, Maidong Decoction, etc. These drugs can relieve cough symptoms by regulating the function of the lungs and resolving phlegm-heat and phlegm-dampness. With the continuous change of clinical needs, compound traditional Chinese medicines have received increasing attention, and better therapeutic effects can be achieved through the compatibility of multiple drugs.

[0003] In recent years, compound traditional Chinese medicines based on bamboo extracts (such as fresh bamboo, bamboo shavings, etc.) have made great research progress in relieving cough and resolving phlegm. Traditional Chinese medicines with fresh bamboo as the main ingredient have the effects of clearing heat and moistening the lung, and resolving phlegm and relieving cough, and are suitable for patients with phlegm-heat cough. Through reasonable compatibility with other traditional Chinese medicines such as Astragalus membranaceus, Fritillaria cirrhosa, Trichosanthes kirilowii, etc., the comprehensive curative effect of the drugs can be enhanced, and a wider range of patient groups can be adapted. The bamboo shavings extract in the compound fresh bamboo preparation has a unique effect of regulating qi and resolving phlegm, and is particularly suitable for symptoms of heat cough and dry throat. The synergistic effect of different drug components helps to comprehensively regulate the body and solve the problem of insufficient curative effect of a single drug.

[0004] The compound fresh bamboo traditional Chinese medicine composition has multiple advantages in relieving cough: First, it can comprehensively regulate the respiratory function through multiple mechanisms (such as clearing heat and resolving phlegm, warming yang and dispelling cold, nourishing yin and moistening the lung), and provide effective treatment for different types of cough. Second, through the synergistic effect of each medicinal material, the compound drug reduces the possible side effects caused by the use of a single medicinal material and has better safety. Finally, fresh bamboo and its related extracts have a strong effect of clearing heat and moistening dryness, and are particularly suitable for heat cough. However, this composition also has certain defects. For example, fresh bamboo is cold in nature and is not suitable for patients with spleen-stomach deficiency-cold. In addition, the components of the compound are complex, and long-term use may have an adverse effect on the spleen-stomach function, so individualized adjustment is required according to the patient's constitution. Summary of the Invention

[0005] In order to solve the above problems, the present invention first provides a compound fresh bamboo traditional Chinese medicine composition for relieving cough and its application.

[0006] The present invention provides a compound fresh bamboo traditional Chinese medicine composition for relieving cough, which is prepared from raw materials with the following weights: 15 - 20 g of fresh bamboo, 15 - 20 g of astragalus membranaceus, 8 - 10 g of cassia twig, 6 - 10 g of trichosanthes kirilowii, 6 - 10 g of fritillaria cirrhosa, 6 - 10 g of raw pinellia ternata, 3 - 5 g of peucedanum praeruptorum, 3 - 5 g of mulberry bark, 3 - 5 g of licorice root, and 3 - 5 g of platycodon grandiflorum.

[0007] In some embodiments, the traditional Chinese medicine composition is prepared from raw materials with the following weights: 15 g of fresh bamboo, 15 g of astragalus membranaceus, 10 g of cassia twig, 8 g of trichosanthes kirilowii, 10 g of fritillaria cirrhosa, 10 g of raw pinellia ternata, 5 g of peucedanum praeruptorum, 5 g of mulberry bark, 3 g of licorice root, and 3 g of platycodon grandiflorum.

[0008] In some embodiments, the traditional Chinese medicine composition is prepared from raw materials with the following weights: 20 g of fresh bamboo, 15 g of astragalus membranaceus, 8 g of cassia twig, 6 g of trichosanthes kirilowii, 8 g of fritillaria cirrhosa, 8 g of raw pinellia ternata, 5 g of peucedanum praeruptorum, 3 g of mulberry bark, 3 g of licorice root, and 5 g of platycodon grandiflorum.

[0009] In some embodiments, the traditional Chinese medicine composition is prepared from raw materials with the following weights: 20 g of fresh bamboo, 20 g of astragalus membranaceus, 8 g of cassia twig, 8 g of trichosanthes kirilowii, 8 g of fritillaria cirrhosa, 6 g of raw pinellia ternata, 3 g of peucedanum praeruptorum, 3 g of mulberry bark, 3 g of licorice root, and 3 g of platycodon grandiflorum.

[0010] In some embodiments, the traditional Chinese medicine composition is prepared from raw materials with the following weights: 15 g of fresh bamboo, 15 g of astragalus membranaceus, 8 g of cassia twig, 8 g of trichosanthes kirilowii, 6 g of fritillaria cirrhosa, 8 g of raw pinellia ternata, 5 g of peucedanum praeruptorum, 5 g of mulberry bark, 3 g of licorice root, and 3 g of platycodon grandiflorum.

[0011] In some embodiments, the traditional Chinese medicine composition is prepared from raw materials with the following weights: 20 g of fresh bamboo, 15 g of astragalus membranaceus, 10 g of cassia twig, 10 g of trichosanthes kirilowii, 8 g of fritillaria cirrhosa, 10 g of raw pinellia ternata, 5 g of peucedanum praeruptorum, 5 g of mulberry bark, 5 g of licorice root, and 3 g of platycodon grandiflorum.

[0012] In addition, the present invention also provides an application of a traditional Chinese medicine preparation in the preparation of a drug for treating cough.

[0013] Each traditional Chinese medicine raw material of the present invention has a unique mechanism of action in relieving cough, forming a prescription with comprehensive therapeutic effects. It mainly relieves cough symptoms through multiple actions such as clearing heat and resolving phlegm, warming the middle-jiao and dispelling cold, tonifying qi and strengthening the healthy qi, and dispersing the lung qi and relieving cough.

[0014] King drugs: fresh bamboo, astragalus membranaceus

[0015] Fresh bamboo: clears heat and resolves phlegm, moistens the lung and relieves cough. It is mainly used to treat cough caused by phlegm-heat obstructing the lung. By clearing lung heat, diluting phlegm, and reducing the viscosity in the respiratory tract, it relieves cough.

[0016] Astragalus membranaceus: Tonifies qi, strengthens the spleen, eliminates pathogenic factors and supports healthy qi. Astragalus membranaceus enhances the body's immune function, especially for cough caused by qi deficiency. By strengthening the transportation and transformation functions of the lung and spleen, it helps to clear phlegm-dampness and improve cough symptoms. Astragalus membranaceus also has the effect of strengthening the constitution, enabling the body to better resist external pathogenic factors during the treatment process.

[0017] Ministerial herbs: Cinnamomum cassia, Trichosanthes kirilowii, Fritillaria cirrhosa, Pinellia ternata

[0018] Cinnamomum cassia: Warm the channels and dispel cold, promote yang and transform qi. Cinnamomum cassia has the effect of warming the lung and dispelling cold, and is suitable for cold cough or cough with phlegm-dampness caused by cold pathogens. It promotes the dispersing of lung qi by warming the qi mechanism, and alleviates the symptoms of cold cough.

[0019] Trichosanthes kirilowii: Clear heat and resolve phlegm, moisten the dryness and widen the chest. Trichosanthes kirilowii clears heat-phlegm and dry-phlegm, dredges the airway, and helps to expectorate phlegm. It is especially suitable for chest tightness and cough symptoms caused by phlegm-heat.

[0020] Fritillaria cirrhosa: Clear heat and moisten the lung, resolve phlegm and relieve cough. It has good curative effects on patients with heat cough, dry cough with little phlegm or sticky phlegm that is difficult to expectorate. The lung-moistening effect of Fritillaria cirrhosa can relieve throat dryness and reduce the frequency of cough.

[0021] Pinellia ternata: Dry dampness and resolve phlegm, lower adverse qi and relieve cough. Pinellia ternata has a strong effect on resolving thick phlegm, especially for cough with damp-phlegm obstructing the lung. By reducing the mucus in the trachea, it reduces the cough response.

[0022] Assistant herbs: Peucedanum praeruptorum, Morus alba root bark

[0023] Peucedanum praeruptorum: Lower qi and resolve phlegm, disperse the lung and relieve cough. The main effect of Peucedanum praeruptorum is to lower qi and resolve phlegm, making the phlegm in the airway easier to expectorate. It is suitable for symptoms of excessive phlegm and frequent cough.

[0024] Morus alba root bark: Drain the lung and relieve asthma, clear heat and resolve phlegm. Morus alba root bark is mainly used to treat cough and asthma due to lung heat. Its effect of draining the lung can quickly reduce lung heat and help relieve cough, excessive phlegm, asthma and other symptoms caused by lung heat.

[0025] Guiding herb: Glycyrrhiza uralensis, Platycodon grandiflorum

[0026] Glycyrrhiza uralensis: Harmonize the properties of various herbs, moisten the lung and relieve cough. Glycyrrhiza uralensis is often used as a guiding herb to harmonize the properties of herbs, and has certain effects of moistening the lung, relieving cough, and alleviating spasm. In traditional Chinese medicine prescriptions, Glycyrrhiza uralensis can also reduce the irritation of drugs to the stomach and enhance the overall curative effect.

[0027] Platycodon grandiflorum: Disperse the lung and soothe the throat, resolve phlegm and drain pus. As a guiding herb that leads the effects of other herbs upward, Platycodon grandiflorum can direct the effects of other herbs directly to the lungs. At the same time, it helps to expectorate phlegm and relieve throat discomfort.

[0028] This prescription plays a comprehensive conditioning role for different types of coughs (such as cold, heat, phlegm-damp coughs) through multiple mechanisms including clearing heat, moistening the lungs, warming yang, and resolving phlegm. Fresh bamboo and astragalus membranaceus, as the sovereign drugs, play a basic role in clearing the lungs and resolving phlegm, and replenishing qi; ministerial drugs such as cinnamon twig and trichosanthes fruit further enhance the therapeutic effect by warming the lungs and dispelling cold, clearing heat and moistening dryness; adjuvant drugs peucedanum praeruptorum and mulberry bark help to disperse the lung qi and expel phlegm, while licorice root and platycodon grandiflorum play a role in harmonizing and guiding the medicinal effects, enabling the medicinal effects to reach the affected area directly. This composition exerts the effects of clearing heat and moistening the lungs and replenishing qi through fresh bamboo and astragalus membranaceus as the sovereign drugs, and cooperates with ministerial drugs trichosanthes fruit, fritillaria cirrhosa, cinnamon twig, and raw pinellia ternata to further clear heat and resolve phlegm and warm yang and dispel cold. Adjuvant drugs peucedanum praeruptorum and mulberry bark help to lower qi and resolve phlegm and assist in the conditioning of lung function. Finally, licorice root and platycodon grandiflorum harmonize the medicinal properties and guide the drugs upward. This compatibility is applicable to cough patients with deficiency-cold of the spleen and stomach complicated by phlegm-heat.

[0029] In addition, the combination of the Chinese medicinal materials in the above ratios of the present invention can significantly improve the body weight of mice with deficiency-cold of the spleen and stomach, significantly prolong the cough latency of mice with deficiency-cold of the spleen and stomach, reduce the number of coughs in mice, and has a significant antitussive effect; at the same time, it can significantly increase the excretion amount of phenol red in the trachea of mice with deficiency-cold of the spleen and stomach, and has a significant effect on resolving phlegm. Detailed implementation manners

[0030] To make the technical problems, technical solutions, and advantages to be solved by the present invention clearer, the following will be described in detail with reference to specific embodiments.

[0031] Example 1

[0032] A compound fresh bamboo Chinese medicinal composition 1 for relieving cough is prepared from the following raw materials by weight:

[0033] Fresh bamboo 15 g, astragalus membranaceus 15 g, cinnamon twig 10 g, trichosanthes fruit 8 g, fritillaria cirrhosa 10 g, raw pinellia ternata 10 g, peucedanum praeruptorum 5 g, mulberry bark 5 g, licorice root 3 g, platycodon grandiflorum 3 g.

[0034] Example 2

[0035] A compound fresh bamboo Chinese medicinal composition 2 for relieving cough is prepared from the following raw materials by weight:

[0036] Fresh bamboo 20 g, astragalus membranaceus 15 g, cinnamon twig 8 g, trichosanthes fruit 6 g, fritillaria cirrhosa 8 g, raw pinellia ternata 8 g, peucedanum praeruptorum 5 g, mulberry bark 3 g, licorice root 3 g, platycodon grandiflorum 5 g.

[0037] Example 3

[0038] A compound fresh bamboo Chinese medicinal composition 3 for relieving cough is prepared from the following raw materials by weight:

[0039] Fresh bamboo 20 g, astragalus membranaceus 20 g, cinnamon twig 8 g, trichosanthes fruit 8 g, fritillaria cirrhosa 8 g, raw pinellia ternata 6 g, peucedanum praeruptorum 3 g, mulberry bark 3 g, licorice root 3 g, platycodon grandiflorum 3 g.

[0040] Example 4

[0041] A compound fresh bamboo traditional Chinese medicine composition 4 for relieving cough is prepared from the following raw materials by weight:

[0042] Fresh bamboo 15g, astragalus membranaceus 15g, cassia twig 8g, trichosanthes kirilowii 8g, fritillaria cirrhosa 6g, raw pinellia ternata 8g, peucedanum praeruptorum 5g, mulberry bark 5g, licorice root 3g, platycodon grandiflorum 3g.

[0043] Example 5

[0044] A compound fresh bamboo traditional Chinese medicine composition 5 for relieving cough is prepared from the following raw materials by weight:

[0045] Fresh bamboo 20g, astragalus membranaceus 15g, cassia twig 10g, trichosanthes kirilowii 10g, fritillaria cirrhosa 8g, raw pinellia ternata 10g, peucedanum praeruptorum 5g, mulberry bark 5g, licorice root 5g, platycodon grandiflorum 3g.

[0046] Example 6

[0047] A preparation method of a compound fresh bamboo traditional Chinese medicine composition for relieving cough comprises the following steps: taking fresh bamboo, astragalus membranaceus, cassia twig, trichosanthes kirilowii, fritillaria cirrhosa, raw pinellia ternata, peucedanum praeruptorum, mulberry bark, licorice root, and platycodon grandiflorum, weighing according to the dosage described in the formula of any one of Examples 1-5, respectively crushing all the medicinal materials into coarse powder, usually about 80 meshes. Soaking the coarsely crushed medicinal materials in 8 times the amount of water (i.e., 8 times the total weight of the medicinal materials), standing for 30 minutes to allow the medicinal materials to fully absorb water, and then decocting with warm water twice. For the first time, after adding water and bringing to a boil, change to a low heat and decoct for 40 minutes; for the second time, add 6 times the amount of water and decoct for 30 minutes, combine the liquids obtained from the two decoctions, filter to remove the medicinal residues to obtain a water extract. Then add ethanol with a concentration of 50% to the remaining medicinal residues, soak according to 5 times the volume of the weight of the medicinal materials for 24 hours. After soaking, perform ethanol reflux extraction: reflux with a water bath at about 60°C for 2 hours, keep the temperature constant during the reflux process, and collect the extract. After the reflux extraction is completed, perform secondary extraction: add the same volume of ethanol, reflux for 1 hour, and collect the two ethanol extracts. Respectively perform vacuum concentration treatment on the water extract and the ethanol extract to remove the excess solvent and obtain relatively concentrated extracts. Combine and mix the concentrated water extract and the ethanol extract to obtain 200 mL of a concentrated traditional Chinese medicine compound extract.

[0048] Example 7 Pharmacological Animal Experiment

[0049] Establishment of a spleen and stomach yang deficiency mouse model: Male ICR mice were exposed to a low-temperature environment (usually around 4°C) for 2-3 hours per day for 1-2 weeks to simulate the damage of the cold environment to the spleen and stomach, thereby causing the mice to become weak. The body weight of the mice in the spleen and stomach yang deficiency state will decrease significantly, and at the same time, they will show weakness, loss of appetite, and reduced food intake, indicating the successful establishment of the spleen and stomach yang deficiency mouse model.

[0050] Effect of the compound fresh bamboo traditional Chinese medicine composition on the body weight of spleen and stomach yang deficiency mice: The 70 successfully established male ICR spleen and stomach yang deficiency mice were divided into Chinese medicine group 1 (200 mL / kg), Chinese medicine group 2 (200 mL / kg), Chinese medicine group 3 (200 mL / kg), Chinese medicine group 4 (200 mL / kg), Chinese medicine group 5 (200 mL / kg), and model group (200 mL / kg normal saline). Among them, the normal group (200 mL / kg normal saline) was healthy male ICR mice, with 10 mice in each group. Each administration group was given intragastric administration once a day for 28 consecutive days, and the changes in the initial and final body weights of the mice were recorded, as shown in Table 1.

[0051] Table 1 Effect of the compound fresh bamboo traditional Chinese medicine composition on the body weight of spleen and stomach yang deficiency mice (n = 10)

[0052]

[0053]

[0054] Note: Compared with the normal group, a P < 0.05, b P < 0.01.

[0055] The results in Table 1 show that compared with the normal group, the body weight growth rate of the mice in the model group decreased significantly (P < 0.05); compared with the model group, the body weight growth rates of the mice in Chinese medicine group 1, Chinese medicine group 2, Chinese medicine group 3, Chinese medicine group 4, and Chinese medicine group 5 all increased significantly (P < 0.05 or P < 0.01), indicating that the compound fresh bamboo traditional Chinese medicine composition of the present invention has a significant effect on improving the body weight of spleen and stomach yang deficiency mice.

[0056] Establishment of a cough model in mice with spleen-stomach yang deficiency: The 80 successfully established male ICR mice with spleen-stomach yang deficiency were divided into a pentoxyverine group (15.0 mg / kg), a Guilong Kechuanning group (0.68 g / kg), a traditional Chinese medicine group 1 (200 mL / kg), a traditional Chinese medicine group 2 (200 mL / kg), a traditional Chinese medicine group 3 (200 mL / kg), a traditional Chinese medicine group 4 (200 mL / kg), a traditional Chinese medicine group 5 (200 mL / kg), and a blank group (200 mL / kg normal saline), with 10 mice in each group. Each administration group was given intragastric administration once a day for 28 consecutive days. One hour after the last administration, a 500 mL wide-mouth bottle was inverted on the operating table, and a cotton ball with 0.3 mL concentrated ammonia water was placed inside. After 20 s of volatilization, the cotton ball was taken out, and the mice were quickly placed into the wide-mouth bottle. The cough latency and the number of coughs within 2 min of the mice were observed and recorded, as shown in Table 2.

[0057] Table 2 Effects of the compound fresh bamboo traditional Chinese medicine composition on the cough latency and the number of coughs in mice with spleen-stomach yang deficiency (n = 10)

[0058]

[0059]

[0060] Note: Compared with the blank group, a P < 0.05, b P < 0.01.

[0061] The results in Table 2 show that compared with the blank group, the cough latency in the pentoxyverine group, the Guilong Kechuanning group, and the traditional Chinese medicine groups 1 - 5 was significantly prolonged (P < 0.05 or P < 0.01); the number of coughs in each administration group of mice was significantly reduced compared with the blank group (P < 0.05 or P < 0.01). This indicates that the compound fresh bamboo traditional Chinese medicine composition of the present invention significantly prolongs the cough latency in mice with spleen-stomach yang deficiency, reduces the number of coughs in mice, and has a significant antitussive effect.

[0062] Establishment of the tracheal phenol red excretion model in mice with weak constitution: The 80 successfully established male ICR mice with spleen and stomach deficiency-cold were divided into the bromhexine group (15.0 mg / kg), the Guilong Kechuanning group (0.68 g / kg), the traditional Chinese medicine group 1 (200 mL / kg), the traditional Chinese medicine group 2 (200 mL / kg), the traditional Chinese medicine group 3 (200 mL / kg), the traditional Chinese medicine group 4 (200 mL / kg), the traditional Chinese medicine group 5 (200 mL / kg), and the blank group (200 mL / kg normal saline), with 10 mice in each group. Each administration group was given intragastric administration once a day for 28 consecutive days. 1 hour after the last administration, the mice were intraperitoneally injected with 20 mL / kg of 5% phenol red normal saline solution. 30 minutes later, the trachea was removed and placed in 4 mL of normal saline, and 0.2 mL of 5% sodium bicarbonate solution was added, and shaken to completely release the phenol red in the trachea. The OD value was measured at 546 nm, and the excretion amount of phenol red was calculated according to the standard curve of phenol red, as shown in Table 3.

[0063] Table 3 Effects of the compound fresh bamboo traditional Chinese medicine composition on the tracheal phenol red excretion amount in mice with spleen and stomach deficiency-cold (n = 10)

[0064] Group Phenol red excretion amount / (ng / mL) Blank group 1.23±0.36 Bromhexine group <![CDATA[2.45±0.64 a > Guilong Kechuanning group <![CDATA[2.56±0.45 a > Traditional Chinese medicine group 1 <![CDATA[3.14±0.62 b > Traditional Chinese medicine group 2 <![CDATA[3.45±0.47 a > Traditional Chinese medicine group 3 <![CDATA[3.72±0.52 b > Traditional Chinese medicine group 4 <![CDATA[3.63±0.37 a > Traditional Chinese medicine group 5 <![CDATA[3.27±0.46 a >

[0065] Note: Compared with the blank group, a P < 0.05, b P < 0.01.

[0066] The results in Table 3 show that compared with the blank group, the phenol red excretion amounts of the mice in the bromhexine group, the Guilong Kechuanning group, and the traditional Chinese medicine groups 1 - 5 were significantly increased (P < 0.05 or P < 0.01), indicating that the compound fresh bamboo traditional Chinese medicine composition of the present invention can significantly increase the tracheal phenol red excretion amount in mice with spleen and stomach deficiency-cold and has a significant expectorant effect.

[0067] The above is the preferred implementation manner of the present invention. It should be noted that for those of ordinary skill in the art in this technical field, without departing from the principle described in the present invention, several improvements and refinements can be made, and these improvements and refinements should also be regarded as the protection scope of the present invention.

Claims

1. A composite fresh bamboo traditional Chinese medicine composition for treating cough due to spleen and stomach deficiency and cold with phlegm and heat, the composition is prepared from the following raw materials by weight: 15-20g fresh bamboo, 15-20g astragalus, 8-10g cassia twig, 6-10g trichosanthes, 6-10g fritillaria, 6-10g cirrhosa, 6-10g raw pinellia, 3-5g peucedanum, 3-5g mulberry bark, 3-5g liquorice, and 3-5g platycodon.

2. The Chinese medicine composition according to claim 1, characterized in that: The Chinese medicine composition is prepared from the following raw materials by weight: 15g fresh bamboo, 15g astragalus, 10g cinnamon twig, 8g trichosanthes, 10g fritillaria, 10g raw pinellia, 5g peucedanum, 5g mulberry bark, 3g liquorice and 3g platycodon.

3. The Chinese medicine composition according to claim 1, characterized in that The Chinese medicine composition is prepared from the following raw materials by weight: 20g fresh bamboo, 15g astragalus, 8g cinnamon twig, 6g trichosanthes, 8g fritillaria, 8g raw pinellia, 5g peucedanum, 3g mulberry bark, 3g liquorice, and 5g platycodon.

4. The Chinese medicine composition according to claim 1, characterized in that: The Chinese medicine composition is prepared from the following raw materials by weight: 20g fresh bamboo, 20g astragalus, 8g cinnamon twig, 8g trichosanthes, 8g fritillaria, 6g raw pinellia, 3g peucedanum, 3g mulberry bark, 3g liquorice, and 3g platycodon.

5. The Chinese medicine composition according to claim 1, characterized in that: The Chinese medicine composition is prepared from the following raw materials by weight: 15g fresh bamboo, 15g astragalus, 8g cinnamon twig, 8g trichosanthes, 6g fritillaria, 8g raw pinellia, 5g peucedanum, 5g mulberry bark, 3g liquorice, and 3g platycodon.

6. The Chinese medicine composition according to claim 1, characterized in that: The Chinese medicine composition is prepared from the following raw materials by weight: 20g fresh bamboo, 15g astragalus, 10g cinnamon twig, 10g trichosanthes, 8g fritillaria, 10g raw pinellia, 5g peucedanum, 5g mulberry bark, 5g liquorice and 3g platycodon.

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