Single-tube multi-bend adjustable angiographic catheter and manufacturing method thereof

Abstract

The invention discloses a single-tube multi-bend type adjustable angiographic catheter and a manufacturing method thereof. The single-tube multi-bend type adjustable angiographic catheter comprises a main catheter and a traction assembly. The main catheter is provided with a supporting section and an adjustable bending section; a first channel is formed in the supporting section; a first shaping block is arranged in the adjustable bending section; the first shaping block is provided with a first bending shape, so that the adjustable bending section is bent according to the first bending shape; the first shaping block axially slides in the adjustable bending section; the traction assembly comprises a first traction wire, one end of the first traction wire extends out of the near-end opening of the first channel, and the other end is connected with the first shaping block; the first traction wire is pushed and pulled to drive the first shaping block to move in the adjustable bending section in the axial direction, so that the position of the first bending part of the adjustable bending section is changed. The problems that the operation process is complex and multi-bend selection is needed before an operation can be solved, the catheter can move upwards in place, the super-selection operation difficulty is reduced, and the operation duration is shortened.

Description

Technical Field

[0001] The invention relates to the technical field of medical catheters, and in particular to a single-tube multi-bend adjustable angiography catheter and a manufacturing method thereof. Background Art

[0002] The angiography catheter is a key device in clinical percutaneous angiography. The appearance of the angiography catheter is a long tube, which is mainly used to provide a channel for the contrast agent to be smoothly introduced into the blood vessels to produce angiography effect. There are many types of catheters usually used for interventional diagnosis and treatment of vascular diseases, which can be divided into diagnostic angiography catheters and therapeutic angiography catheters.

[0003] The femoral artery approach has long been considered a conventional approach for cerebral angiography. Figure 1 The following are three types of bends of the catheter tip currently used for femoral artery intervention, namely VTK bend, HI bend, and H2 bend. These bends are suitable for superselective operation of the aortic arch during femoral artery intervention. Users need to select the type according to the actual situation of different approaches to meet the requirements of various vascular structures for the tip.

[0004] As a classic approach for cerebrovascular disease intervention, the femoral artery approach has certain drawbacks, such as hematoma at the puncture site, arteriovenous leakage, and the need for a long period of bed rest after surgery. Therefore, many scholars have begun to try other approaches, such as the radial artery approach.

[0005] Compared with the femoral artery approach, the radial artery approach has more advantages in reducing surgical complications and increasing patient comfort. For example, the radial artery is located superficially, and the risk of nerve damage and arteriovenous leakage caused by puncture is significantly lower than that of the femoral artery; there is no need to interrupt antiplatelet and anticoagulant drug treatment during the examination; no perineum preparation is required before surgery, and no bed rest is required after surgery. However, with the clinical application of radial artery cerebrovascular intervention, it has gradually been found that it is more difficult than the femoral artery approach, such as radial artery puncture is more difficult than femoral artery puncture, the selective cannulation process is cumbersome, the catheter is difficult to control, the success rate of selective cannulation of secondary blood vessels on the aortic arch is low, the operator needs a longer learning time, and the operator is exposed to more radiation during the operation than when the femoral artery approach is used.

[0006] Considering the advantages of radial artery access in reducing complications and increasing patient comfort, the proportion of radial artery access in cerebrovascular interventional treatment has been gradually expanded clinically. For radial interventional surgery, angiography is indispensable, whether it is a separate angiography examination before surgery or an auxiliary treatment during surgery, so the use of angiography catheters is bound to increase significantly.

[0007] Figure 2The following is a SIM curved catheter used in the current transradial artery interventional treatment. The conventional SIM curved catheters shown are SIM1, SIM2 and SIM3. SIM1, SIM2 and SIM3 are the same curved type with different curved extension lengths. The SIM curved shape is specifically designed for conventional superselective operations through the radial artery approach. The curved shape is suitable for neurointerventional operations through the right radial approach to the left carotid artery. The most commonly used operation is descending aorta looping.

[0008] However, whether it is a VTK curved, HI curved, or H2 curved angiography catheter for femoral artery access, or a SIM curved angiography catheter for radial artery access, the shape of the tip is fixed.

[0009] At present, the main pain point of angiographic catheter interventional surgery is the complex access conditions, and the vascular conditions of patients vary greatly due to their different physical conditions; therefore, the surgeon must solve the problem of choosing the bend and bend length before the operation; secondly, the surgeon is restricted by the bend length defined by the single bend during the operation, and the vascular conditions of different individuals vary greatly, resulting in the inability to completely match the shape of the angiographic catheter tip with the vascular structure in actual operation. These require the surgeon to use rich operating experience and spend more time to solve them during the operation, which is difficult and time-consuming. The surgeon also needs more time to practice "superselection" operations after surgery. For hospitals with low surgical volume or small and medium-sized hospitals, it is difficult to carry out the operation and it is difficult to master the "superselection" operation in complex blood pathways. During the "superselection" operation to establish the access route, the catheter often bends, kinks, falls off, cannot be put in place, and the catheter bend type is improperly selected, which not only greatly increases the operation time, but also increases the risk of the operation.

[0010] Therefore, there is an urgent need for a single-tube, multi-bend adjustable angiography catheter that can solve the problem of complex surgical procedures and the need for multiple bend selections before surgery, and can enable the catheter to be moved upward to the correct position, reduce the difficulty of superselective operations, and save surgical time. Summary of the invention

[0011] In order to overcome the shortcomings of the prior art, the present invention provides a single-tube multi-bend adjustable angiography catheter and a manufacturing method thereof, which can solve the problem of complex surgical procedures and the need for multiple bend selections before surgery. The catheter has the characteristics of being able to move upward to a high position, reducing the difficulty of super-selective operations and shortening the operation time.

[0012] The first aspect of the present invention provides a single-tube multi-bend adjustable angiography catheter, comprising a main catheter and a traction assembly;

[0013] The main catheter is a slender tubular structure with a tube wall and an inner tube cavity; the main catheter is sequentially formed with a support section and an adjustable bend section from the proximal end to the distal end;

[0014] A first channel is formed in the support section for the traction assembly to pass through;

[0015] A first shaping block is arranged in the adjustable bending section; the first shaping block is inserted in the adjustable bending section, and the first shaping block forms a first bending portion at a contact position with the adjustable bending section; the first shaping block is sleeve-shaped, has a first bending shape, and has shape-retaining ability, so that the first bending portion is bent in the first bending shape; the first shaping block is slidably connected to the adjustable bending section, so that the first shaping block can be displaced axially relative to the adjustable bending section;

[0016] The traction assembly includes a first traction wire, the first traction wire is inserted into the first channel, two ends of the first traction wire form a traction end and a connection end respectively, the traction end of the first traction wire extends from the proximal opening of the first channel, the connection end of the first traction wire extends from the distal opening of the first channel, and the connection end of the first traction wire is connected to the first shaping block;

[0017] By pushing and pulling the first traction wire, the first shaping block is driven to move axially in the adjustable bending section, so that the position of the first bending portion of the adjustable bending section is changed.

[0018] In the first aspect of the present invention, as a preferred embodiment, the wall of the bending section tube is provided with an inner lining layer, a braided layer and an outer tube layer in sequence from the inside to the outside; an adjustment chamber is formed between the inner lining layer and the support layer; the adjustment chamber is connected to the first channel; and the first shaping block is slidably connected in the adjustment chamber.

[0019] In the first aspect of the present invention, as a preferred embodiment, it further includes a second shaping block and a third shaping block;

[0020] The second shaping block is inserted into the adjustable bending section, and the first shaping block forms a second bending portion at the contact position with the adjustable bending section; the second shaping block is sleeve-shaped, and the second shaping block has a second bending shape, and the second shaping block has shape-retaining ability, so that the second bending portion is bent in the second bending shape; the second shaping block is slidably connected to the adjustable bending section, so that the second shaping block can be displaced axially relative to the adjustable bending section;

[0021] The third shaping block is inserted into the adjustable bending section, and the contact position between the third shaping block and the adjustable bending section forms a third bending portion; the third shaping block is sleeve-shaped, and has a third bending shape. The third shaping block has shape-retaining ability, so that the third bending portion is bent in the third bending shape; the third shaping block is slidably connected to the adjustable bending section, so that the third shaping block can be displaced axially relative to the adjustable bending section;

[0022] The first shaping block, the second shaping block and the third shaping block are sequentially arranged in the adjustment chamber from the proximal end to the distal end.

[0023] In the first aspect of the present invention, as a preferred embodiment, a first connecting wire is provided between the first shaping block and the second shaping block, and two ends of the first connecting wire are respectively fixedly connected to the first shaping block and the second shaping block;

[0024] A second connecting wire is provided between the second shaping block and the third shaping block, and two ends of the second connecting wire are respectively fixedly connected to the second shaping block and the third shaping block;

[0025] By pushing and pulling the first traction wire, the first shaping block, the second shaping block and the third shaping block are simultaneously driven to move axially in the adjustment chamber, thereby changing the positions of the first bending portion, the second bending portion and the third bending portion of the adjustable bending section.

[0026] In the first aspect of the present invention, as a preferred embodiment, the adjustment chamber is provided with A11 position, A12 position and A13 position in sequence from the distal end to the proximal end, and the first shaping block can move among the A11 position, A12 position and A13 position; when the first shaping block is in the A11 position, the adjustable bend section of the main guide tube is a SIM1 bend shape.

[0027] In the first aspect of the present invention, as a preferred embodiment, a second channel and a third channel are formed in the support section;

[0028] The traction assembly includes a second traction wire and a third traction wire;

[0029] The second traction wire is inserted into the second channel, and the two ends of the second traction wire form a traction end and a connection end respectively. The traction end of the second traction wire extends from the proximal opening of the second channel, and the connection end of the second traction wire extends from the distal opening of the second channel. The connection end of the second traction wire is connected to the second shaping block; by pushing and pulling the second traction wire, the second shaping block is driven to move axially in the adjustment chamber, so that the position of the second bending portion of the adjustable bending section is changed;

[0030] The third traction wire is inserted into the third channel, and two ends of the third traction wire form a traction end and a connecting end respectively. The traction end of the third traction wire extends from the proximal opening of the third channel, and the connecting end of the third traction wire extends from the distal opening of the third channel. The connecting end of the third traction wire is connected to the third shaping block. By pushing and pulling the third traction wire, the third shaping block is driven to move axially in the adjustment chamber, thereby changing the position of the third bending portion of the adjustable bending section.

[0031] In the first aspect of the present invention, as a preferred embodiment, the adjustment chamber is provided with A21 position, A22 position, A23 position; B1 position, B2 position, B3 position; C1 position, C2 position, C3 position in sequence from the distal end to the proximal end;

[0032] The first shaping block can move between position A21, position A22, and position A23;

[0033] The second shaping block can move between position B1, position B2, and position B3;

[0034] The third shaping block can move between position C1, position C2, and position C3;

[0035] When the first shaping block is at the A21 position, the second shaping block is at the B1 position, and the third shaping block is at the C1 position, the adjustable bend section of the main conduit is in a SIM1 bend shape;

[0036] When the first shaping block is at the A22 position, the second shaping block is at the B2 position, and the third shaping block is at the C2 position, the adjustable bend section of the main conduit is a SIM2 bend;

[0037] When the first shaping block is at the A23 position, the second shaping block is at the B3 position, and the third shaping block is at the C3 position, the adjustable bend section of the main conduit is a SIM3 bend.

[0038] In the first aspect of the present invention, as a preferred embodiment, it also includes a catheter seat, which is connected to the proximal end of the main catheter through a stress release tube; the catheter seat is provided with a bend adjustment rotary valve, which is connected to the traction assembly, and the bend adjustment rotary valve pushes and pulls the first traction wire, the second traction wire, and the third traction wire by rotating, thereby controlling the first shaping block, the second shaping block, and the third shaping block to move in the adjustment chamber for bending;

[0039] The bending rotary valve has a first gear position, a second gear position and a third gear position;

[0040] When the bend adjusting rotary valve is rotated to the first gear position, the first shaping block is at the A21 position, the second shaping block is at the B1 position, and the third shaping block is at the C1 position, so that the adjustable bend section of the main conduit is in a SIM1 bend shape;

[0041] When the bend adjusting rotary valve is rotated to the second gear position, the first shaping block is at the A22 position, the second shaping block is at the B2 position, and the third shaping block is at the C2 position, so that the adjustable bend section of the main conduit is in a SIM2 bend shape;

[0042] When the bend adjusting rotary valve is rotated to the third gear, the first shaping block is at the A23 position, the second shaping block is at the B3 position, and the third shaping block is at the C3 position, the adjustable bend section of the main conduit presents a SIM3 bend shape.

[0043] In the first aspect of the present invention, as a preferred embodiment, the support section tube wall is provided with an inner lining layer, a braided layer and an outer tube layer in sequence from the inside to the outside;

[0044] The inner lining layer of the adjustable bending section and the inner lining layer of the supporting section are both made of polytetrafluoroethylene;

[0045] The adjustable bending section braided layer and the supporting section braided layer are both braided by multiple strands of stainless steel wire;

[0046] The outer tube layer of the adjustable bending section and the outer tube layer of the supporting section include polyetheramide resin and barium sulfate;

[0047] The first traction wire, the second traction wire and the third traction wire are formed by twisting and weaving multiple strands of stainless steel wires;

[0048] The first shaping block, the second shaping block and the third shaping block are formed by laser engraving and bending a stainless steel tube or a nickel-titanium tube.

[0049] A second aspect of the present invention provides a method for manufacturing a single-tube multi-bend adjustable angiography catheter, comprising the following steps:

[0050] A liner tube is provided, wherein the liner tube is made of polytetrafluoroethylene; the liner tube has a first segment and a second segment in sequence from the proximal end to the distal end;

[0051] Providing a plurality of braided wires, and braiding the braided wires on the surface of the first segment of the liner tube to form a first braided layer;

[0052] Providing a rheological material, the rheological material comprising polyetheramide resin and barium sulfate, and flowing the rheological material onto the surface of the first braided layer to form a first rheological layer;

[0053] Providing a first cladding tube, a second cladding tube and a third cladding tube, and fixing the first cladding tube, the second cladding tube and the third cladding tube in sequence on the surface of the first rheological layer;

[0054] Provide a plurality of braided wires, braid the braided wires on the surface of the auxiliary tube to form a second braided tube; sleeve the second braided tube on the first cladding tube, the second cladding tube, the third cladding tube, the surface of the first rheological layer and the second segmented surface of the liner tube; provide a rheological material, the rheological material includes polyetheramide resin and barium sulfate, and rheologically conduct the rheological material on the surface of the second braided tube in segments to form a second rheological layer; at this time, an adjustment chamber is formed between the second braided tube and the liner tube, and the far end of the adjustment chamber has an open mouth;

[0055] Providing a plurality of stainless steel wires, twisting the plurality of stainless steel wires into a traction wire, and cutting the traction wire into a first traction wire, a second traction wire, and a third traction wire;

[0056] Provide a plurality of stainless steel tubes or nickel-titanium tubes, laser engrave the stainless steel tubes or nickel-titanium tubes, cut out a first sleeve, a second sleeve and a third sleeve after engraving, bend the first sleeve, the second sleeve and the third sleeve into a first bend shape, a second bend shape and a third bend shape respectively, and perform heat treatment to make them have shape-retaining ability, thereby forming a first shaping block, a second shaping block and a third shaping block; connect the first shaping block, the second shaping block and the third shaping block to the ends of the first traction wire, the second traction wire and the third traction wire respectively.

[0057] Insert the free ends of the first traction wire, the second traction wire and the third traction wire from the distal end into the first covering tube, the second covering tube and the third covering tube respectively, until they pass out from the proximal outlets of the first covering tube, the second covering tube and the third covering tube, continue to pull the first traction wire, the second traction wire and the third traction wire, and insert the third shaping block, the second shaping block and the first shaping block into the inside of the regulating chamber from the open mouth at the distal end of the regulating chamber in sequence;

[0058] Providing a rheological material, the rheological material comprising polyetheramide resin and barium sulfate, rheologically allowing the rheological material to flow to the surface of the second rheological layer, and sealing the adjustment chamber to form an outer tube layer; coating the surface of the outer tube layer with a hydrophilic coating to obtain a main tube;

[0059] A catheter seat and a stress release tube are provided, and the catheter seat and the stress release tube are installed to the proximal end of the main catheter body; a bending adjustment rotary valve is provided on the catheter seat, and the first traction wire, the second traction wire and the third traction wire are respectively connected to the bending adjustment rotary valve, and the bending adjustment rotary valve is rotated to push and pull the first traction wire, the second traction wire and the third traction wire, thereby controlling the first shaping block, the second shaping block and the third shaping block to move in the adjustment chamber, and adjusting the initial state of the distal end of the main catheter to a SIM1 bend.

[0060] Compared with the prior art, the present invention has the following beneficial effects:

[0061] 1. The single-tube multi-bend adjustable angiographic catheter of the present invention applies a push-pull force to the first traction wire, thereby driving the first shaping block connected to the distal end of the first traction wire to axially displace in the adjustable bend section, thereby changing the position of the first bend portion of the adjustable bend section, thereby achieving a change in the bend shape of the distal head end of the angiographic catheter, that is, multi-bend control of a single catheter, which meets clinical usage scenarios, does not require multiple judgments on bend selection before surgery, saves preoperative evaluation and selection time, solves the problem of complex surgical procedures and the absence of multiple bend selections before surgery, and has the advantages that the catheter can be moved up to a high position, reducing the difficulty of super-selection operations and saving surgical time.

[0062] 2. The single-tube multi-bend adjustable angiography catheter of the present invention is SIM-shaped in its natural state without pre-shaping. It is designed based on the most commonly used bend of the radial catheter, and can solve more than 95% of the problems of transradial superselection and angiography. It can quickly adjust the bend by adjusting the bend according to the clinical situation based on the minimum SIM1 bend and pulling. The bend shaping block is carried out in the form of pulling, the traction rope is inelastic, the pulling force is transmitted 1:1, there is no loss in the process, real-time feedback, and the bend adjustment is accurate. During the adjustment process, a transitional SIM bend beyond the conventional can be adjusted, and the operability is strong.

[0063] 3. Conventional SIM catheters are single-bend catheters. Even if the operation can be completed, it is not a perfect match. It is limited by the bend length defined by the single bend, and can only be solved by the doctor through operation and time. The single-tube multi-bend adjustable angiography catheter of the present invention can have many intermediate transition bends such as SIM1.5 and SIM2.5 during the transition from SIM1 to SIM3. With finer size and length, it can better adapt to each person's special blood vessels under the conditions of blood vessels that are more suitable for different physiques, avoid forced matching by doctors to complete the operation, reduce the learning curve of doctors, and perform rapid surgery. It can better respond to emergencies and other emergencies, shorten the treatment time, and effectively benefit the golden time for treatment; broaden the new way of radial artery interventional treatment; reduce the difficulty of learning curve operation, so that more small and medium-sized hospitals have the ability to carry out interventional surgery and save more people. BRIEF DESCRIPTION OF THE DRAWINGS

[0064] Figure 1 Schematic diagram of three types of bends of the tip of a femoral artery interventional angiography catheter involved in the background technology;

[0065] Figure 2 A schematic diagram of a SIM bend at the tip of a radial artery interventional angiography catheter involved in the background technology;

[0066] Figure 3 It is a schematic structural diagram of a single-tube multi-bend adjustable angiography catheter of the present invention;

[0067] Figure 4 It is a schematic diagram of the AA cross-sectional structure of the single-tube multi-bend adjustable angiography catheter of the present invention;

[0068] Figure 5 It is a schematic structural diagram of the adjustable bend section of the single-tube multi-bend adjustable angiography catheter of the present invention;

[0069] Figure 6 It is a schematic diagram of the use state of the first shaping block of the single-tube multi-bend adjustable angiography catheter of the present invention;

[0070] Figure 7 It is a schematic diagram of the use state of the first shaping block of another embodiment of the single-tube multi-bend adjustable angiography catheter of the present invention;

[0071] Figure 8 It is a schematic diagram of the use status of the adjustable bend section of the single-tube multi-bend adjustable angiography catheter of the present invention.

[0072] In the figure: 10, support section; 20, adjustable bending section; 21, inner lining layer; 22, braided layer; 23, adjusting chamber; 24, outer tube layer; 25, first channel; 26, first bending portion; 27, second bending portion; 28, third bending portion; 30, first shaping block; A21, A21 position; A22, A22 position; A23, A23 position; 40, second shaping block; B1, B1 position; B2, B2 position; B3, B3 position; 50, third shaping block; C1, C1 position; C2, C2 position; C3, C3 position; 60, first traction wire; 70, catheter seat; 71, bending adjustment valve; 711, first gear position; 712, second gear position; 713, third gear position. DETAILED DESCRIPTION

[0073] Below, in conjunction with the accompanying drawings and specific embodiments, the invention is further described. It should be noted that, under the premise of no conflict, the various embodiments described below or the various technical features can be arbitrarily combined to form a new embodiment. Except as otherwise specified, the materials and equipment used in this embodiment can be purchased from the market. Examples of the embodiments are shown in the accompanying drawings, in which the same or similar reference numerals throughout represent the same or similar elements or elements with the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present application, and cannot be understood as limiting the present application.

[0074] In the description of the present application, it should be understood that the terms "upper", "lower", "front", "back", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific position, be constructed and operated in a specific position, and therefore cannot be understood as a limitation on the present application. In the description of the present application, "plurality" means two or more, unless otherwise precisely and specifically specified.

[0075] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "connected", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, or it can be connected through an intermediary medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0076] The terms "first", "second", etc. in the specification and claims of this application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions. For example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.

[0077] like Figure 3-8 As shown, this embodiment provides a single-tube multi-bend adjustable angiography catheter, which is mainly used to provide a pipeline so that contrast agents can be smoothly introduced into blood vessels to produce angiography effects. It includes a main catheter, a traction assembly catheter seat 70, and a stress release tube connected between the proximal end of the main catheter and the catheter seat 70;

[0078] The proximal end referred to in this embodiment is the end closer to the operator when in use, and the distal end is the end farther from the operator when in use, and the central axis is the line connecting the distal center and the proximal center in a natural state; the inner side of this embodiment refers to the side relatively close to the central axis, and the outer side refers to the side relatively far from the central axis; the proximal end of the main catheter in this embodiment is used to connect with operating equipment such as a stress relief tube and a catheter seat 70, and the distal end is used for entry, which can be understood by those skilled in the art.

[0079] The main catheter is a slender tubular structure with a tube wall and an inner tube cavity; the main catheter is formed with a support section 10 and an adjustable bend section 20 in sequence from the proximal end to the distal end. The effective length of the main catheter in this embodiment is 90-160cm, and the length of the adjustable bend section is 2-20cm from the distal end; the surface of the main catheter is coated with a hydrophilic coating, the coating length is 20-80cm, the inner diameter of the main catheter lumen is 1-2.5mm, and the outer diameter is 1.3-3.3mm. A first channel 25 is formed in the tube wall of the support section 10 for the traction assembly to pass through, and the first channel 25 has a proximal opening and a distal opening.

[0080] A first shaping block 30 is arranged in the adjustable bending section 20; the first shaping block 30 is penetrated in the adjustable bending section 20, and the first shaping block 30 forms a first bending portion 26 at the contact position with the adjustable bending section 20; the first shaping block 30 is in the shape of a sleeve, and the first shaping block 30 has a first bending shape, and the first shaping block 30 has a shape-retaining ability, so that the first bending portion 26 is bent in the first bending shape; the first shaping block 30 is slidably connected to the adjustable bending section 20, so that the first shaping block 30 can be displaced axially relative to the adjustable bending section 20.

[0081] The traction assembly includes a first traction wire 60, which is inserted into the first channel 25. The two ends of the first traction wire 60 form a traction end and a connecting end respectively. The traction end of the first traction wire 60 extends from the proximal opening of the first channel 25, and the connecting end of the first traction wire 60 extends from the distal opening of the first channel 25. The connecting end of the first traction wire 60 is connected to the first shaping block 30.

[0082] When in use, a push-pull force is applied to the first traction wire 60 extending from the proximal opening of the first channel 25, thereby driving the first shaping block 30 connected to the distal end of the first traction wire 60 to move axially in the adjustable bend section 20, thereby changing the position of the first bending portion 26 of the adjustable bend section 20, thereby achieving a change in the bend shape of the distal tip of the angiography catheter.

[0083] The first shaping block 30 of the present embodiment may be formed by laser engraving and bending a stainless steel tube or a nickel-titanium tube, and heat-treated to give it an excellent shape-retaining ability. Figure 6What is shown is an implementation mode of the first shaping block 30, which is inserted into the adjustable bend section 20 and supported inside the adjustable bend section 20 by surface tension. It temporarily stays at a preset position by utilizing the abutment force and friction force of its own bending shape, and drives the contact part with the adjustable bend section 20 to bend in a preset shape. When in use, the abutment force and friction force between the first shaping block 30 and the inner wall of the adjustable bend section 20 are overcome by pushing and pulling the first traction wire 60, so that the first shaping block 30 slides relative to the inner wall of the adjustable bend section 20, the first shaping block 30 is axially displaced a distance, and the position of the first bending portion 26 is changed accordingly, thereby adjusting the bend shape of the distal tip of the angiography catheter.

[0084] Figure 7 Another embodiment of the first shaping block 30 is shown, wherein the wall of the bending section is provided with an inner lining layer 21, a braided layer 22 and an outer tube layer 24 in sequence from the inside to the outside; an adjusting chamber 23 is formed between the inner lining layer 21 and the supporting layer; the adjusting chamber 23 is connected to the first channel 25; and the first shaping block 30 is slidably connected to the adjusting chamber 23. The independently provided adjusting chamber 23 provides a more stable and reliable environment for the sliding of the first shaping block 30 in the adjustable bending section 20, and is not easy to interfere with the passage established by the inner tube cavity of the main tube.

[0085] The inner lining layer 21 of the adjustable bend section 20 can be made of PTFE (polytetrafluoroethylene) material to establish a flat and lubricated inner cavity, which is convenient for other instruments to pass through. The braided layer 22 of the adjustable bend section 20 is woven from multiple strands of stainless steel braided wires, and the braided wires include but are not limited to original round wires, flat wires, and round and flat mixed wires, and have strong anti-deformation ability. The outer tube layer 24 of the adjustable bend section 20 is composed of Pebax (polyetheramide resin) of different hardness, and the barium sulfate material contained therein can be developed under radiation. The inner lining layer 21, the braided layer 22 and the outer tube layer 24 are sequentially arranged on the tube wall of the support section 10 from the inside to the outside, and the corresponding materials are consistent with the adjustable bend section.

[0086] The first traction wire 60 of this embodiment is made of stainless steel material, which has good material rigidity and toughness. The first traction wire 60 is twisted and braided by multiple strands of stainless steel wire, and can be quickly bent in the form of pulling. The traction rope is inelastic, and the pulling force is transmitted 1:1, without loss in the process, and real-time feedback. The first shaping block 30 can be controlled by one first traction wire 60, or two first traction wires 60 can be set at 180° intervals, or multiple first traction wires 60 in a ring array can be controlled, which correspondingly improves the balance and stability of the first shaping block 30 when sliding. Those skilled in the art can implement it according to actual needs.

[0087] Specifically, this embodiment further includes a second shaping block 40 and a third shaping block 50;

[0088] The second shaping block 40 is inserted into the adjustable bending section 20, and the first shaping block 30 forms a second bending portion 27 at the contact position with the adjustable bending section 20; the second shaping block 40 is sleeve-shaped, and has a second bending shape. The second shaping block 40 has shape-retaining ability, so that the second bending portion 27 is bent in the second bending shape; the second shaping block 40 is slidably connected to the adjustable bending section 20, so that the second shaping block 40 can be displaced axially relative to the adjustable bending section 20;

[0089] The third shaping block 50 is inserted into the adjustable curved section 20, and the third shaping block 50 and the third curved section 20 contact position form a third bending portion 28; the third shaping block 50 is sleeve-shaped, and the third shaping block 50 has a third bending shape. The third shaping block 50 has shape-retaining ability, so that the third bending portion 28 is bent in the third bending shape; the third shaping block 50 is slidably connected to the adjustable curved section 20, so that the third shaping block 50 can be displaced axially relative to the adjustable curved section 20;

[0090] The first shaping block 30 , the second shaping block 40 , and the third shaping block 50 are sequentially disposed in the regulating chamber 23 from the proximal end to the distal end.

[0091] In one embodiment, the first shaping block 30, the second shaping block 40, and the third shaping block 50 can be connected in series. That is, a first connecting wire is provided between the first shaping block 30 and the second shaping block 40, and the two ends of the first connecting wire are respectively fixed to the first shaping block 30 and the second shaping block; a second connecting wire is provided between the second shaping block 40 and the third shaping block 50, and the two ends of the second connecting wire are respectively fixed to the second shaping block 40 and the third shaping block 50. By connecting in series, the first shaping block 30, the second shaping block 40, and the third shaping block 50 are linked by the first connecting wire at a preset spacing. When in use, only one pulling wire needs to be pushed and pulled to simultaneously drive the first shaping block 30, the second shaping block 40, and the third shaping block 50 to move axially in the adjustment chamber 23, so that the positions of the first bending portion 26, the second bending portion 27, and the third bending portion 28 of the adjustable bending section 20 are changed, and the adjustment of the head end bending type is completed. It has the characteristics of simple structure, convenient processing, and convenient control operation. The initial bending type is set to SIM1 bending type. When the first shaping block 30, the second shaping block 40, and the third shaping block 50 are pulled in series, the axial displacement is performed at the same displacement amount spacing, and the adjustment of the SIM1 bending type to the approximate SIM2 bending type and the approximate SIM3 bending type can be completed. There is a deviation from the SIM2 bending type and the SIM3 bending type, but it is also within an acceptable range and can meet certain operational requirements.

[0092] In a preferred embodiment, the first shaping block 30, the second shaping block 40, and the third shaping block 50 are independently controlled by different traction wires.

[0093] Specifically, a second channel and a third channel are formed in the support section 10; the traction assembly includes a second traction wire and a third traction wire;

[0094] The second traction wire is inserted into the second channel, and the two ends of the second traction wire form a traction end and a connection end respectively. The traction end of the second traction wire extends from the proximal opening of the second channel, and the connection end of the second traction wire extends from the distal opening of the second channel. The connection end of the second traction wire is connected to the second shaping block 40; by pushing and pulling the second traction wire, the second shaping block 40 is driven to move axially in the adjustment chamber 23, so that the position of the second bending portion 27 of the adjustable bending section 20 is changed;

[0095] The third traction wire is inserted into the third channel, and the two ends of the third traction wire form a traction end and a connecting end respectively. The traction end of the third traction wire extends from the proximal opening of the third channel, and the connecting end of the third traction wire extends from the distal opening of the third channel. The connecting end of the third traction wire is connected to the third shaping block 50; by pushing and pulling the third traction wire, the third shaping block 50 is driven to move axially in the adjustment chamber 23, thereby changing the position of the third bending portion 28 of the adjustable bending section 20.

[0096] When in use, the displacement of the first shaping block 30 is controlled by pulling the first traction wire 60, the displacement of the second shaping block 40 is controlled by pulling the second traction wire, and the displacement of the third shaping block 50 is controlled by pulling the third traction wire, so that the positions of the first bending portion 26, the second bending portion 27, and the third bending portion 28 of the adjustable bending section 20 are changed accordingly. The initial bending type is set to SIM1 bending type, which can adjust the actual shape closer to SIM2 bending type or SIM3 bending type, and the operability is stronger.

[0097] Furthermore, the regulating chamber 23 is provided with A21 position A21, A22 position A22, A23 position A23 in sequence from the distal end to the proximal end; B1 position B1, B2 position B2, B3 position B3; C1 position C1, C2 position C2, C3 position C3;

[0098] The first shaping block 30 can move between position A21 A21, position A22 A22, and position A23 A23;

[0099] The second shaping block 40 can move between position B1, position B2 and position B3;

[0100] The third shaping block 50 can move between the C1 position C1, the C2 position C2, and the C3 position C3;

[0101] When the first shaping block 30 is at the A21 position A21, the second shaping block 40 is at the B1 position B1, and the third shaping block 50 is at the C1 position C1, the adjustable curved section 20 of the main conduit is in a SIM1 curved shape;

[0102] When the first shaping block 30 is at the A22 position A22, the second shaping block 40 is at the B2 position B2, and the third shaping block 50 is at the C2 position C2, the adjustable curved section 20 of the main conduit is in a SIM2 curved shape;

[0103] When the first shaping block 30 is at the A23 position A23, the second shaping block 40 is at the B3 position B3, and the third shaping block 50 is at the C3 position C3, the adjustable bend section 20 of the main conduit presents a SIM3 bend shape.

[0104] The catheter seat 70 of this embodiment is made of PC material, including a catheter seat body and a bend adjustment rotary valve 71. One end of the catheter seat body is a standard Luer connector, and the other end is connected to the inner lumen of the main catheter, which can be used for instrument passage and injection of diagnostic reagents such as angiography. The bend adjustment rotary valve 71 is connected to the traction assembly, and the bend adjustment rotary valve 71 pushes and pulls the first traction wire 60, the second traction wire, and the third traction wire by rotation, thereby controlling the first shaping block 30, the second shaping block 40, and the third shaping block 50 to move in the adjustment chamber 23 for bending.

[0105] The bend regulating rotary valve 71 has a first gear position 711, a second gear position 712 and a third gear position 713;

[0106] When the bend adjusting rotary valve 71 is rotated to the first gear position 711, the first shaping block 30 is at the A21 position A21, the second shaping block 40 is at the B1 position B1, and the third shaping block 50 is at the C1 position C1, so that the adjustable bend section 20 of the main conduit is in a SIM1 bend shape;

[0107] When the bend adjusting rotary valve 71 is rotated to the second gear position 712, the first shaping block 30 is at the A22 position A22, the second shaping block 40 is at the B2 position B2, and the third shaping block 50 is at the C2 position C2, so that the adjustable bend section 20 of the main conduit is in a SIM2 bend shape;

[0108] When the bending adjustment rotary valve 71 is rotated to the third gear position 713, the first shaping block 30 is at the A23 position A23, the second shaping block 40 is at the B3 position B3, and the third shaping block 50 is at the C3 position C3, the adjustable bending section 20 of the main conduit presents a SIM3 bending type.

[0109] In this way, the rapid switching of SIM1, SIM2, and SIM3 can be achieved without complicated pulling operations, with high precision and simple operation, saving the operator's operation time during the operation and preoperative training time. Of course, in the actual implementation process, the transition gear bend type between SIM1, SIM2, and SIM3 can also be set to make it more practical and flexible. In some other implementations, the initial bend type can also be set to VTK bend type, H1 bend type, H2 bend type, and other custom bend types, etc., which are more flexible, and technical personnel in this field can implement it according to actual needs.

[0110] Based on the above structure, the method for using the single-tube multi-bend adjustable angiography catheter of this embodiment in neurointervention surgery is as follows, including the following steps:

[0111] Step S101: Check whether the outside of the packaging box is obviously damaged. Take out the sterile bag from the packaging box and check whether it is damaged (ie, torn, punctured, scratched, etc.). If the sterile bag has been opened or damaged, do not use it.

[0112] Step S102: Carefully open the sterile bag, take out the angiography catheter, check whether the product is damaged, and flush the inner and outer cavities of the catheter with heparinized saline. Note: If the product is damaged, do not use it.

[0113] Step S103: A guide wire of suitable size pre-soaked in heparinized saline is inserted into the single-tube multi-bend adjustable angiography catheter described in this embodiment through the catheter seat 70 until it passes through a length of about 5 cm from the tip.

[0114] Step S104: Select relevant equipment to establish vascular access.

[0115] Step S105: After the passage is established, the single-tube multi-bend adjustable angiography catheter described in this embodiment is inserted into the blood vessel along the guide wire (or matched with other interventional catheters to be coaxially inserted into the blood vessel).

[0116] Step S106: Perform the superselection operation under X-ray fluoroscopy, and in the process, control the bend type by adjusting the bend knob 71 to confirm whether the head end of the angiography catheter is indeed inserted into the target site, and then perform the contrast agent or drug injection operation. Note: Before injecting the contrast agent or drug, make sure that the product is not knotted, broken, twisted, or blocked.

[0117] Step S107: If the angiography catheter is to be sent to the distal end of the blood vessel, the guide wire is inserted again, with the guide wire advanced first, and the product is carefully inserted along the guide wire.

[0118] Step S108: When performing the operation using the coaxial method, the guide wire is pulled out, and a sub-catheter (micro-catheter) is carefully inserted into the lumen of the main catheter of the angiography catheter.

[0119] Step S109: When replacing other catheters, move the angiography catheter away from the target site, reinsert the guide wire so that it slightly protrudes from the tip of the angiography catheter, and carefully replace the catheter along the guide wire.

[0120] Step S110: After the predetermined operation is completed, the angiography catheter is moved away from the target position, and a guide wire is inserted so that the guide wire slightly extends out of the distal end of the catheter, and the catheter and the guide wire are carefully removed together.

[0121] The single-tube multi-bend adjustable angiography catheter of this embodiment applies a push-pull force to the first traction wire 60, driving the first shaping block 30 connected to the distal end of the first traction wire 60 to move axially in the adjustable bend section 20, thereby changing the position of the first bend portion 26 of the adjustable bend section 20, and realizing the change of the bend type of the distal head end of the angiography catheter; that is, a single catheter multi-bend control meets clinical use scenarios, does not require multiple judgments on bend selection before surgery, saves preoperative evaluation and selection time, solves the problem of complex surgical procedures and the lack of preoperative multiple bend selection, and has the advantages of the catheter being able to go up to a high position, reducing the difficulty of superselection operation, and saving surgical time. The natural state is SIM type, without pre-shaping. Based on the most commonly used bend type of transradial surgery, it can solve more than 95% of transradial superselection and angiography problems. Initially based on the minimum SIM1 bend, the bend is adjusted according to the clinical situation for traction, and the bend can be adjusted quickly; the bend shaping block is carried out in the form of traction, the traction rope is inelastic, the traction force is transmitted 1:1, there is no loss in the process, real-time feedback, and the bend adjustment is accurate. During the adjustment process, a transitional SIM bend other than the conventional one can be adjusted; the conventional SIM catheter is selected and is a single bend type. Even if the operation can be completed, it is not a complete match. It is limited by the bend length limited by the single bend type, and can only be solved by the doctor through operation and time. The single-tube multi-bend adjustable angiography catheter of this embodiment may have many intermediate transition bends such as SIM1.5 and SIM2.5 during the transition from SIM1 to SIM3. It can better adapt to each person's special blood vessels with finer size and length under vascular conditions that are more suitable for different physiques, avoid forced matching by doctors to complete operations, reduce the learning curve of doctors, and implement rapid surgery, which can better respond to emergencies and other emergencies, shorten treatment time, and effectively benefit the golden time for treatment; broaden the new mode of radial artery interventional treatment; reduce the difficulty of learning curve operation, so that more small and medium-sized hospitals have the ability to carry out interventional surgery and save more people.

[0122] Example 2

[0123] This embodiment provides a method for manufacturing a single-tube multi-bend adjustable angiography catheter, which is mainly used to manufacture a single-tube multi-bend adjustable angiography catheter as in Example 1, comprising the following steps:

[0124] Step S201: providing an inner liner tube, wherein the inner liner tube is made of polytetrafluoroethylene; the inner liner tube has a first segment and a second segment in sequence from the proximal end to the distal end.

[0125] Step S202 : providing a plurality of braided wires, and braiding the braided wires on the surface of the first segment of the liner tube to form a first braided layer 22 .

[0126] Step S203: providing a rheological material, wherein the rheological material includes polyetheramide resin and barium sulfate, and allowing the rheological material to flow onto the surface of the first braided layer 22 to form a first rheological layer.

[0127] Step S204: Provide a first cladding tube, a second cladding tube, and a third cladding tube, and fix the first cladding tube, the second cladding tube, and the third cladding tube on the surface of the first rheological layer in sequence; the first cladding tube, the second cladding tube, and the third cladding tube extend distally to the second segmented surface of the liner tube, and the first cladding tube, the second cladding tube, and the third cladding tube are provided with connecting grooves on one side facing the second segmented surface. The first cladding tube, the second cladding tube, and the third cladding tube have a first channel 25, a second channel, and a third channel inside for the traction wire to pass through.

[0128] Step S205: provide a plurality of braided wires, and braid the braided wires on the surface of the auxiliary tube to form a second braided tube; sleeve the second braided tube on the first covering tube, the second covering tube, the third covering tube, the surface of the first rheological layer and the second segment surface of the lining tube; provide a rheological material, the rheological material includes polyetheramide resin and barium sulfate, and segmentally rheologically apply the rheological material to the surface of the second braided tube to form a second rheological layer; at this time, the second rheological layer rheostatically integrates the first rheological layer, the first covering tube, the second covering tube, the third covering tube and the first segment of the second braided tube; the second rheological layer rheostatically integrates the first covering tube, the second covering tube, the third covering tube and the second braided tube extending to the surface of the second segment, and at this time, an adjustment chamber 23 is formed between the second braided tube and the lining tube, and the far end of the adjustment chamber 23 has an open mouth.

[0129] Step S206: providing a plurality of stainless steel wires, twisting the plurality of stainless steel wires into a traction wire, and cutting the traction wire into a first traction wire 60 , a second traction wire, and a third traction wire.

[0130] Step S207: Provide a plurality of stainless steel tubes or nickel-titanium tubes, laser engrave the stainless steel tubes or nickel-titanium tubes, cut out a first sleeve, a second sleeve and a third sleeve after engraving, bend the first sleeve, the second sleeve and the third sleeve into a first bend shape, a second bend shape and a third bend shape respectively, and perform heat treatment to make them have shape-retaining ability, thereby forming a first shaping block 30, a second shaping block 40 and a third shaping block 50.

[0131] Step S208: Provide a first plug-in, a second plug-in and a third plug-in; fix one end of the first plug-in to the first shaping block 30, and the other end to the end of the first traction wire 60; fix one end of the second plug-in to the second shaping block 40, and the other end to the end of the second traction wire; fix one end of the third plug-in to the third shaping block 50, and the other end to the end of the third traction wire.

[0132] Step S209: Insert the free ends of the first traction wire 60, the second traction wire and the third traction wire from the distal end into the first sheathing tube, the second sheathing tube and the third sheathing tube respectively until they pass out from the proximal outlets of the first sheathing tube, the second sheathing tube and the third sheathing tube, continue to pull the first traction wire 60, the second traction wire and the third traction wire, so that the first plug-in, the second plug-in and the third plug-in are respectively inserted into the connecting grooves of the first sheathing tube, the second sheathing tube and the third sheathing, and the third shaping block 50, the second shaping block 40 and the first shaping block 30 are sequentially inserted into the interior of the regulating chamber 23 from the open mouth at the distal end of the regulating chamber 23.

[0133] Step S209: providing a rheological material, the rheological material comprising polyetheramide resin and barium sulfate, allowing the rheological material to flow to the surface of the second rheological layer, and sealing the adjustment chamber 23 to form an outer tube layer 24; coating the surface of the outer tube layer 24 with a hydrophilic coating to obtain a main tube.

[0134] Step S210: Provide a catheter seat 70 and a stress release tube, and install the catheter seat 70 and the stress release tube to the proximal end of the main catheter body; the catheter seat 70 is provided with a bending adjustment rotary valve 71, and the first traction wire 60, the second traction wire and the third traction wire are respectively connected to the bending adjustment rotary valve 71, and the bending adjustment rotary valve 71 is rotated to push and pull the first traction wire 60, the second traction wire and the third traction wire, thereby controlling the first shaping block 30, the second shaping block 40 and the third shaping block 50 to move in the adjustment chamber 23, and adjusting the initial state of the distal end of the main catheter to a SIM1 bend.

[0135] The above-mentioned embodiments are only preferred embodiments of the present invention and cannot be used to limit the scope of protection of the present invention. Any non-substantial changes and substitutions made by technicians in this field on the basis of the present invention shall fall within the scope of protection required by the present invention.

Claims

1. A single-tube multi-bend adjustable angiography catheter, characterized in that: It includes a main pipe and a traction assembly; The main catheter is a slender tubular structure with a tube wall and an inner tube cavity; the main catheter is sequentially formed with a support section and an adjustable bend section from the proximal end to the distal end; A first channel is formed in the support section for the traction assembly to pass through; A first shaping block is arranged in the adjustable bending section; the first shaping block is inserted in the adjustable bending section, and the first shaping block forms a first bending portion at a contact position with the adjustable bending section; the first shaping block is sleeve-shaped, has a first bending shape, and has shape-retaining ability, so that the first bending portion is bent in the first bending shape; the first shaping block is slidably connected to the adjustable bending section, so that the first shaping block can be displaced axially relative to the adjustable bending section; The traction assembly includes a first traction wire, the first traction wire is inserted into the first channel, two ends of the first traction wire form a traction end and a connection end respectively, the traction end of the first traction wire extends from the proximal opening of the first channel, the connection end of the first traction wire extends from the distal opening of the first channel, and the connection end of the first traction wire is connected to the first shaping block; By pushing and pulling the first traction wire, the first shaping block is driven to move axially in the adjustable bending section, so that the position of the first bending portion of the adjustable bending section is changed.

2. The single-tube multi-bend adjustable angiography catheter according to claim 1, characterized in that: The tube wall of the bending section is provided with an inner lining layer, a braided layer and an outer tube layer in sequence from the inside to the outside; an adjustment chamber is formed between the inner lining layer and the support layer; the adjustment chamber is connected to the first channel; and the first shaping block is slidably connected in the adjustment chamber.

3. The single-tube multi-bend adjustable angiography catheter according to claim 2, characterized in that: Also includes a second shaping block and a third shaping block; The second shaping block is inserted into the adjustable bending section, and the first shaping block forms a second bending portion at the contact position with the adjustable bending section; the second shaping block is sleeve-shaped, and the second shaping block has a second bending shape, and the second shaping block has shape-retaining ability, so that the second bending portion is bent in the second bending shape; the second shaping block is slidably connected to the adjustable bending section, so that the second shaping block can be displaced axially relative to the adjustable bending section; The third shaping block is inserted into the adjustable bending section, and the contact position between the third shaping block and the adjustable bending section forms a third bending portion; the third shaping block is sleeve-shaped, and has a third bending shape. The third shaping block has shape-retaining ability, so that the third bending portion is bent in the third bending shape; the third shaping block is slidably connected to the adjustable bending section, so that the third shaping block can be displaced axially relative to the adjustable bending section; The first shaping block, the second shaping block and the third shaping block are sequentially arranged in the adjustment chamber from the proximal end to the distal end.

4. The single-tube multi-bend adjustable angiography catheter according to claim 3, characterized in that: A first connecting wire is provided between the first shaping block and the second shaping block, and two ends of the first connecting wire are respectively fixedly connected to the first shaping block and the second shaping block; A second connecting wire is provided between the second shaping block and the third shaping block, and two ends of the second connecting wire are respectively fixedly connected to the second shaping block and the third shaping block; By pushing and pulling the first traction wire, the first shaping block, the second shaping block and the third shaping block are simultaneously driven to move axially in the adjustment chamber, thereby changing the positions of the first bending portion, the second bending portion and the third bending portion of the adjustable bending section.

5. The single-tube multi-bend adjustable angiography catheter according to claim 4, characterized in that: Positions A11, A12 and A13 are sequentially arranged in the adjustment chamber from the distal end to the proximal end, and the first shaping block can move among positions A11, A12 and A13; when the first shaping block is at the A11 position, the adjustable bend section of the main guide tube is a SIM1 bend.

6. The single-tube multi-bend adjustable angiography catheter according to claim 3, characterized in that: A second channel and a third channel are formed in the support section; The traction assembly includes a second traction wire and a third traction wire; The second traction wire is inserted into the second channel, and the two ends of the second traction wire form a traction end and a connection end respectively. The traction end of the second traction wire extends from the proximal opening of the second channel, and the connection end of the second traction wire extends from the distal opening of the second channel. The connection end of the second traction wire is connected to the second shaping block; by pushing and pulling the second traction wire, the second shaping block is driven to move axially in the adjustment chamber, so that the position of the second bending portion of the adjustable bending section is changed; The third traction wire is inserted into the third channel, and two ends of the third traction wire form a traction end and a connecting end respectively. The traction end of the third traction wire extends from the proximal opening of the third channel, and the connecting end of the third traction wire extends from the distal opening of the third channel. The connecting end of the third traction wire is connected to the third shaping block. By pushing and pulling the third traction wire, the third shaping block is driven to move axially in the adjustment chamber, thereby changing the position of the third bending portion of the adjustable bending section.

7. The single-tube multi-bend adjustable angiography catheter according to claim 6, characterized in that: The adjustment chamber is provided with positions A21, A22, and A23 in sequence from the distal end to the proximal end; positions B1, B2, and B3; positions C1, C2, and C3; The first shaping block can be moved between position A21, position A22, and position A23; The second shaping block can move between position B1, position B2, and position B3; The third shaping block can move between position C1, position C2, and position C3; When the first shaping block is at the A21 position, the second shaping block is at the B1 position, and the third shaping block is at the C1 position, the adjustable bend section of the main conduit is in a SIM1 bend shape; When the first shaping block is at the A22 position, the second shaping block is at the B2 position, and the third shaping block is at the C2 position, the adjustable bend section of the main conduit is a SIM2 bend; When the first shaping block is at the A23 position, the second shaping block is at the B3 position, and the third shaping block is at the C3 position, the adjustable bend section of the main conduit is a SIM3 bend.

8. The single-tube multi-bend adjustable angiography catheter according to claim 7, characterized in that: It also includes a catheter seat, which is connected to the proximal end of the main catheter through a stress release tube; the catheter seat is provided with a bend adjustment rotary valve, which is connected to the traction assembly, and the bend adjustment rotary valve pushes and pulls the first traction wire, the second traction wire, and the third traction wire by rotating, thereby controlling the first shaping block, the second shaping block, and the third shaping block to move in the adjustment chamber for bending; The bending rotary valve has a first gear position, a second gear position and a third gear position; When the bend adjusting rotary valve is rotated to the first gear position, the first shaping block is at the A21 position, the second shaping block is at the B1 position, and the third shaping block is at the C1 position, so that the adjustable bend section of the main conduit is in a SIM1 bend shape; When the bend adjusting rotary valve is rotated to the second gear position, the first shaping block is at the A22 position, the second shaping block is at the B2 position, and the third shaping block is at the C2 position, so that the adjustable bend section of the main conduit is in a SIM2 bend shape; When the bend adjusting rotary valve is rotated to the third gear, the first shaping block is at the A23 position, the second shaping block is at the B3 position, and the third shaping block is at the C3 position, the adjustable bend section of the main conduit presents a SIM3 bend shape.

9. The single-tube multi-bend adjustable angiography catheter according to claim 6, characterized in that: The support section pipe wall is provided with an inner lining layer, a braided layer and an outer pipe layer in sequence from the inside to the outside; The inner lining layer of the adjustable bending section and the inner lining layer of the supporting section are both made of polytetrafluoroethylene; The adjustable bending section braided layer and the supporting section braided layer are both braided by multiple strands of stainless steel wire; The outer tube layer of the adjustable bending section and the outer tube layer of the supporting section include polyetheramide resin and barium sulfate; The first traction wire, the second traction wire and the third traction wire are formed by twisting and weaving multiple strands of stainless steel wires; The first shaping block, the second shaping block and the third shaping block are formed by laser engraving and bending a stainless steel tube or a nickel-titanium tube.

10. A method for manufacturing a single-tube multi-bend adjustable angiography catheter, characterized in that: The following steps are involved: A liner tube is provided, wherein the liner tube is made of polytetrafluoroethylene; the liner tube has a first segment and a second segment in sequence from the proximal end to the distal end; Providing a plurality of braided wires, and braiding the braided wires on the surface of the first segment of the liner tube to form a first braided layer; Providing a rheological material, the rheological material comprising polyetheramide resin and barium sulfate, and flowing the rheological material onto the surface of the first braided layer to form a first rheological layer; Providing a first cladding tube, a second cladding tube and a third cladding tube, and fixing the first cladding tube, the second cladding tube and the third cladding tube in sequence on the surface of the first rheological layer; Provide a plurality of braided wires, braid the braided wires on the surface of the auxiliary tube to form a second braided tube; sleeve the second braided tube on the first cladding tube, the second cladding tube, the third cladding tube, the surface of the first rheological layer and the second segmented surface of the liner tube; provide a rheological material, the rheological material includes polyetheramide resin and barium sulfate, and rheologically conduct the rheological material on the surface of the second braided tube in segments to form a second rheological layer; at this time, an adjustment chamber is formed between the second braided tube and the liner tube, and the far end of the adjustment chamber has an open mouth; Providing a plurality of stainless steel wires, twisting the plurality of stainless steel wires into a traction wire, and cutting the traction wire into a first traction wire, a second traction wire, and a third traction wire; A plurality of stainless steel tubes or nickel-titanium tubes are provided, and the stainless steel tubes or nickel-titanium tubes are laser engraved, and a first sleeve tube, a second sleeve tube, and a third sleeve tube are cut out after engraving, and the first sleeve tube, the second sleeve tube, and the third sleeve tube are bent into a first bend shape, a second bend shape, and a third bend shape, respectively, and heat-treated to have shape-retaining ability, so as to form a first shaping block, a second shaping block, and a third shaping block; the first shaping block, the second shaping block, and the third shaping block are connected to the ends of the first traction wire, the second traction wire, and the third traction wire, respectively; Insert the free ends of the first traction wire, the second traction wire and the third traction wire from the distal end into the first covering tube, the second covering tube and the third covering tube respectively, until they pass out from the proximal outlets of the first covering tube, the second covering tube and the third covering tube, continue to pull the first traction wire, the second traction wire and the third traction wire, and insert the third shaping block, the second shaping block and the first shaping block into the inside of the regulating chamber from the open mouth at the distal end of the regulating chamber in sequence; Providing a rheological material, the rheological material comprising polyetheramide resin and barium sulfate, rheologically allowing the rheological material to flow to the surface of the second rheological layer, and sealing the adjustment chamber to form an outer tube layer; coating the surface of the outer tube layer with a hydrophilic coating to obtain a main tube; A catheter seat and a stress release tube are provided, and the catheter seat and the stress release tube are installed to the proximal end of the main catheter body; a bending adjustment rotary valve is provided on the catheter seat, and the first traction wire, the second traction wire and the third traction wire are respectively connected to the bending adjustment rotary valve, and the bending adjustment rotary valve is rotated to push and pull the first traction wire, the second traction wire and the third traction wire, thereby controlling the first shaping block, the second shaping block and the third shaping block to move in the adjustment chamber, and adjusting the initial state of the distal end of the main catheter to a SIM1 bend.

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