Laser generator and ablation system

Abstract

The invention relates to a laser generator and an ablation system.The laser generator comprises a light source used for emitting laser, a beam splitting reflection assembly and a diffusion assembly, the beam splitting reflection assembly is arranged on the light emitting side of the light source, and the beam splitting reflection assembly is arranged to be capable of adjusting the energy of the laser penetrating through the beam splitting reflection assembly; and the diffusion assembly is arranged on an emergent path of the beam splitting and reflecting assembly, and the diffusion assembly is arranged to be capable of homogenizing the beam intensity distribution of the laser. The laser is emitted through the light source, and the laser is modulated through the beam splitting reflection assembly and the diffusion assembly, so that the beam intensity distribution of the laser is homogenized. Therefore, the emergent light formed by the laser generator is prevented from damaging the optical fiber, and the service life of the ablation system is prolonged.

Description

Technical Field

[0001] The present application relates to the technical field of laser ablation, and in particular to a laser generator and an ablation system. Background Art

[0002] With the advancement of medical technology, interventional treatment of cardiovascular and cerebrovascular diseases has become the mainstream and is widely used in the treatment of diseases such as arterial atherosclerosis and stenosis. Among them, the treatment method of using electricity, gas and other energies to conduct into human blood vessels through special means to directly remove atherosclerotic plaques in blood vessels is collectively referred to as volume reduction technology.

[0003] Laser angioplasty is one of the various volume reduction technologies. It is a minimally invasive interventional treatment technology that uses laser energy to ablate stenotic and obstructive lesions in blood vessels, recanalize and reestablish blood flow. When using laser energy for ablation, it is generally necessary to use optical fibers to transmit high peak power pulsed laser energy to ablate plaque tissue or target obstructions.

[0004] However, the laser emitted by the laser generator used for ablation in the related art is prone to damage the optical fiber, thereby increasing the risk of overall failure of the ablation system. Summary of the invention

[0005] Based on this, it is necessary to provide a laser generator and ablation system for laser ablation to address the problem that the laser emitted by the laser generator used for ablation in the related technology is prone to damage the optical fiber, thereby increasing the risk of overall failure of the ablation system.

[0006] A laser generator for laser ablation, the laser generator comprising:

[0007] A light source for emitting laser light;

[0008] A beam splitting and reflecting component is provided at the light emitting side of the light source, and the beam splitting and reflecting component is configured to be able to adjust the energy of the laser passing through the beam splitting and reflecting component; and

[0009] A diffusion component is arranged on the exit path of the beam splitting reflection component, and the diffusion component is configured to be able to homogenize the beam intensity distribution of the laser.

[0010] The laser generator provided in the present application can generate suitable output light for treatment, and then transmit the output light for treatment to the human body through optical fiber for ablation. The present application emits a laser through a light source, and modulates the laser using a beam splitting reflection component and a diffusion component to make the laser beam intensity distribution uniform. The beam splitting reflection component can adjust the energy of the laser, so that the beam quality of the laser entering the diffusion component can be adjusted. In combination with the diffusion component, the laser beam intensity distribution can be homogenized, thereby improving the homogenization effect of the diffusion component on the spatial distribution of the laser, that is, improving the homogenization effect of the diffusion component on the laser beam intensity distribution. Thereby avoiding the output light formed by the laser generator from causing damage to the optical fiber, thereby increasing the service life of the ablation system.

[0011] In one embodiment, the laser generator further includes a first reflector, which is disposed between the beam splitting reflective component and the diffuser component and is capable of reflecting the light emitted from the beam splitting reflective component to the diffuser component.

[0012] In one of the embodiments, the light source is used to emit linearly polarized light, and the beam splitting reflection component includes an energy detection unit, and the energy detection unit is capable of receiving part of the light.

[0013] In one embodiment, the beam splitting reflection component includes a polarization splitting element, which is disposed on the light output side of the light source and is used to split the light into two polarized lights with different polarization state directions and respectively emit them to the energy detection unit and the diffusion component.

[0014] In one embodiment, the beam splitting reflection component includes a beam sampling mirror, which is arranged between the light source and the energy detection unit, and the beam sampling mirror is configured to separate a sample beam from the laser and transmit the sample beam to the energy detection unit.

[0015] In one of the embodiments, the beam splitting reflection component further includes a half-wave plate and a driving element, wherein the half-wave plate is disposed between the polarization beam splitting element and the light source, and the driving element can drive the half-wave plate to rotate around the optical axis of the light source.

[0016] In one embodiment, the beam splitting reflection assembly also includes a control element, which is communicatively connected to the energy detection unit and the driving element, and the control element is used to control the driving element according to the detection result of the energy detection unit to adjust the rotation angle of the half-wave plate relative to the optical axis.

[0017] In one embodiment, the beam splitting reflection assembly also includes a second reflector, and the second reflector and the light source are respectively arranged on two opposite sides of the beam sampling mirror, and the beam sampling mirror can transmit part of the light and reflect another part of the light to the energy detection unit, and the second reflector is used to reflect at least part of the light transmitted by the beam sampling mirror to the first reflector.

[0018] In one of the embodiments, the diffusion component includes a diffuser and a focusing lens, and the diffuser is used to homogenize the light;

[0019] The focusing lens is arranged on a side of the diffuser away from the beam splitting reflection component in the propagation direction of the light path.

[0020] In one of the embodiments, the laser generator includes an indicator light source component, which is disposed on the light-emitting side of the diffusion component and is used to generate visible light with the same optical path as the laser.

[0021] In one embodiment, the indicator light source assembly includes a beam combining lens and an indicator light source, and the indicator light source is used to emit the visible light;

[0022] The beam combining lens is disposed between the diffusion component and the indication light source, and is configured to combine the visible light and the light passing through the diffusion component and then emit the combined light.

[0023] In one embodiment, the light source is configured to emit a laser beam with a wavelength between 200nm and 400nm, a pulse width between 5nsec and 15nsec, and a laser beam quality factor M 2 >5 lasers.

[0024] According to another aspect of the present application, an ablation system is provided, comprising the above-mentioned laser generator and an ablation catheter, wherein the ablation catheter comprises an optical fiber. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 A schematic diagram of the structure of a laser generator for this application;

[0026] Figure 2 for Figure 1 Another structural schematic diagram of the laser generator shown;

[0027] Figure 3 A schematic diagram of the structure of another laser generator provided in this application;

[0028] Figure 4 for Figure 1 Another structural schematic diagram of the laser generator shown;

[0029] Figure 5 for Figure 3 Another structural schematic diagram of the laser generator shown;

[0030] Figure 6 for Figure 1 Another structural schematic diagram of the laser generator shown;

[0031] Figure 7 This is a schematic diagram of the structure of the laser light passing through the half-wave plate 21 and the flat polarization beam splitter in this application;

[0032] Figure 8 This is a schematic diagram of the structure of the laser light passing through the half-wave plate 21 and the cubic polarization beam splitter in this application;

[0033] Fig. 9 The laser beam quality factor M of the beam input to the diffuser for this application is 2 The spatial distribution of the energy of the light beam output by the diffuser when the value of is different.

[0034] Description of reference numerals:

[0035] Laser generator 100;

[0036] Light source 1; beam splitting reflection component 2; half-wave plate 21; polarization splitting element 22; energy detection unit 23; beam sampling mirror 24; diffusion component 3; diffuser 31; focusing lens 32; first reflector 4; second reflector 5; indicator light source component 6; beam combining lens 61; indicator light source 62; optical fiber 7; shutter 8. DETAILED DESCRIPTION

[0037] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present application, so the present application is not limited by the specific embodiments disclosed below.

[0038] In the description of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0039] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of this application, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0040] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0041] In the present application, unless otherwise clearly specified and limited, a first feature being “above” or “below” a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being “above”, “above”, and “above” a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being “below”, “below”, and “below” a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0042] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. The terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used herein are for illustrative purposes only and are not intended to be the only implementation method.

[0043] See also Figure 1 As shown, Figure 1This is a schematic diagram of the structure of a laser generator 100 of the present application. The present application provides a laser generator 100 and an ablation system, the ablation system includes the above-mentioned laser generator 100 and an ablation catheter, and the ablation catheter includes an optical fiber 7. The laser generator 100 is used to generate suitable output light for treatment, and the optical fiber 7 is arranged at the output end of the laser generator 100. The output light modulated by the laser generator 100 is propagated into the optical fiber 7, and then the output light for treatment is transmitted to the patient's to-be-ablated part or to-be-ablated tissue through the optical fiber 7 to ablate it.

[0044] The laser generator 100 of the present application includes a light source 1 for emitting laser light, a beam splitting and reflecting component 2, and a diffusion component 3. The beam splitting and reflecting component 2 is arranged on the light-emitting side of the light source 1, and is used to receive the laser light emitted by the light source 1 and modulate the laser light. In some embodiments, the beam splitting and reflecting component 2 is configured to be able to adjust the energy of the laser light passing through the beam splitting and reflecting component 2. The diffusion component 3 is arranged on the exit path of the beam splitting and reflecting component 2, and the diffusion component 3 is configured to be able to homogenize the intensity distribution of the laser beam. It can be understood that the beam splitting and reflecting component 2 can adjust the energy of the laser light, so that the beam quality of the laser light entering the diffusion component 3 can be adjusted, thereby improving the homogenization effect of the diffusion component 3 on the spatial distribution of the laser light, thereby avoiding the damage of the exit light formed by the laser generator 100 to the optical fiber 7, thereby improving the service life of the ablation system.

[0045] In some embodiments, see Figure 1 As shown, the light source 1 is used to emit a laser light in a linear polarization state, and the beam splitting reflection component 2 includes a polarization beam splitter 22 and an energy detection unit 23. The polarization beam splitter 22 is arranged on the light output side of the light source 1 and is located on the optical axis of the light source 1. The polarization beam splitter 22 can split the laser light emitted by the light source 1 into two polarized lights with different polarization state directions, and can respectively direct the two polarized lights to the energy detection unit 23 and the diffusion component 3. In some embodiments, the polarization beam splitter 22 divides the light into P-type polarized light and S-type polarized light, and directs the P-type polarized light to the energy detection unit 23, and directs the S-type polarized light to the diffusion component 3. In some embodiments, the polarization beam splitter 22 is configured to allow the P-type polarized light to pass through and the S-type polarized light to be reflected. At this time, the S-type polarized light is deflected 90° after passing through the polarization beam splitter 22, and the P-type polarized light passes through the polarization beam splitter 22 and reaches the energy detection unit 23, and is absorbed by the energy detection unit 23.

[0046] It can be understood that the splitting ratio of the polarization beam splitter 22 is a fixed value, and the energy detection unit 23 can measure the energy value of the P-type polarized light according to the photoelectric effect or the pyroelectric effect, and the energy value of the laser emitted by the light source 1 can be calculated according to the splitting ratio of the polarization beam splitter 22. Therefore, the beam splitting reflection component 2 of the present application has the function of monitoring and detecting the energy output of the light source 1, so that the loss of the light source 1 can be judged according to the energy output of the light source 1 detected, and when the loss of the light source 1 is too large or the light source 1 is directly damaged, the light source 1 can be replaced in time.

[0047] In some embodiments, the energy value of the laser emitted by the light source 1 is constant, and the energy value of the P-type polarized light is measured by the energy detection unit 23, and the energy value of the S-type polarized light can be inferred from the splitting ratio of the polarization splitting element 22, so that the beam splitting reflection component 2 of the present application can monitor and detect the energy value of the S-type polarized light transmitted from the beam splitting reflection component 2 to the diffuse component 3.

[0048] In some embodiments, see Figure 1 As shown, the beam splitting and reflecting component 2 also includes a half-wave plate 21 and a driving element. The half-wave plate 21 is arranged between the polarization splitting element 22 and the light source 1, and is located on the optical axis of the light source 1. The half-wave plate 21 can adjust the linearly polarized light emitted by the light source 1. In other words, the half-wave plate 21 rotates a certain angle around the optical axis, and the polarization direction of the linearly polarized light passing through the half-wave plate 21 can be changed. Therefore, by adjusting the angle of rotation of the half-wave plate 21 around the optical axis, the polarization direction of the linearly polarized light passing through the half-wave plate 21 can be changed, and then the light is transmitted to the polarization splitting element 22 for splitting. The polarization splitting element 22 splits the light entering the polarization splitting element 22 into P-type polarized light and S-type polarized light, and the light intensity ratio of the P-type polarized light and the S-type polarized light is related to the polarization direction of the light entering the polarization splitting element 22. The half-wave plate 21 can change the polarization direction of the linearly polarized light emitted by the light source 1. That is, the intensity ratio of the P-type polarized light and the S-type polarized light separated by the polarization splitter 22 can be determined by the rotation angle of the half-wave plate 21 relative to the optical axis.

[0049] In some embodiments, the driving element can drive the half-wave plate 21 to rotate around the optical axis of the light source 1, so that the light intensity ratio of the P-type polarized light and the S-type polarized light separated by the polarization beam splitting element 22 can be adjusted as the half-wave plate 21 rotates. In some embodiments, the half-wave plate 21 can be installed at a fixed angle so that the light intensity ratio of the P-type polarized light and the S-type polarized light separated by the polarization beam splitting element 22 is a constant value, so as to be suitable for the use scenario where the light intensity of the output light of the laser generator 100 does not need to be adjusted, and by fixing the half-wave plate 21, the half-wave plate 21 is made more stable, which can improve the structural stability of the laser generator 100 and make it more resistant to falling.

[0050] In some embodiments, the beam splitting and reflecting component 2 further includes a control element, which is communicatively connected to the energy detection unit 23 and the driving element. The control element can adjust the rotation angle of the half-wave plate 21 relative to the optical axis according to the energy of the light required for the part to be ablated by the patient, thereby adjusting the energy value of the light beam transmitted from the beam splitting and reflecting component 2 to the diffusion component 3, and then changing the light intensity of the output light of the laser generator 100. The energy detection unit 23 can deduce the energy value of the S-type polarized light according to the energy value of the detected P-type polarized light, thereby monitoring the light intensity of the output light of the adjusted laser generator 100. In some embodiments, the control element can automatically control the driving element according to the detection result of the energy detection unit 23 to adjust the rotation angle of the half-wave plate 21 relative to the optical axis, so that the light intensity of the output light of the laser generator 100 is suitable for the corresponding part to be ablated or the tissue to be ablated.

[0051] In some embodiments, the control element may be respectively connected to the detection unit and the driving element in communication via Bluetooth or the like, or respectively connected to the detection unit and the driving element in communication via wires.

[0052] In some embodiments, the beam splitting and reflecting component 2 further includes a display screen electrically connected to the energy detecting unit 23, and can display the monitoring results of the energy detecting unit 23 on the display screen, such as the energy value of the light source 1 derived by detection or the energy value of the light beam transmitted from the beam splitting and reflecting component 2 to the diffusion component 3. In some embodiments, medical personnel can adjust the rotation angle of the half-wave plate 21 relative to the optical axis according to the actual monitoring results on the display screen, so that the light intensity of the output light of the laser generator 100 is suitable for the corresponding part to be ablated or the tissue to be ablated.

[0053] In some embodiments, the half-wave plate 21 can be mounted on a fixed angle mounting frame, or mounted in a manually or electrically driven rotating mounting frame, so as to facilitate adjusting the angle of the half-wave plate 21 .

[0054] In some embodiments, the laser generator 100 of the present application further includes a shutter 8, which is disposed on the light beam propagation path between the first reflector 4 and the diffusion component 3, and the shutter 8 is in communication connection with the control element, and the control element can control the switch of the shutter 8, thereby controlling whether the light beam continues to propagate. It can be understood that if the shutter 8 is opened, the light beam passing through the first reflector 4 continues to propagate from the first reflector 4 to the diffusion component 3, and if the shutter 8 is closed, the light beam passing through the first reflector 4 is blocked and cannot propagate to the diffusion component 3. In other words, the shutter 8 is used to open or close the light beam passing through the first reflector 4 to continue to be transmitted to the downstream optical system.

[0055] In some embodiments, see Figure 1 As shown, the polarization beam splitter element 22 can be configured as a flat polarization beam splitter, see Figure 2As shown, the polarization beam splitter element 22 can also be set as a cubic polarization beam splitter. The cubic polarization beam splitter can choose to use a polarization beam splitter prism. The polarization beam splitter prism is composed of two identical prisms with isosceles right triangle cross sections, whose hypotenuses overlap and are combined into a cubic prism with a square cross section, and then coated at the oblique cross section where the cubic prism overlaps. The function of polarization beam splitting is achieved by coating to form a polarization beam splitter prism. And due to the need of transmitting high peak power pulsed lasers in this application, the polarization beam splitter prism can be formed by a non-adhesive bonding prism. The advantage of the polarization beam splitter prism is that the light beam will not be offset before and after penetrating the polarization beam splitter prism, thereby improving the light beam quality, and it is more convenient to install and calibrate the light path. The advantage of the flat polarization beam splitter is that the cost is low, so the polarization beam splitter element 22 can be set as a flat polarization beam splitter or a polarization beam splitter prism according to actual needs.

[0056] See also Figure 7 and with Figure 8 As shown, Figure 7 This is a schematic diagram of the structure of the laser passing through the half-wave plate 21 and the flat polarization beam splitter in this application. Figure 8 Schematic diagram of the structure of the laser passing through the half-wave plate 21 and the cubic polarization beam splitter in this application. The laser emitted by the light source 1 in this application changes its polarization state after passing through the half-wave plate 21, and the laser after the polarization state is changed passes through the Figure 7 The plate polarizing beam splitter in Figure 8 The neutral cube polarization beam splitter performs beam splitting to split the laser light passing through the polarization beam splitting element 22 into P-type polarized light and S-type polarized light, wherein the P-type polarized light passes through the polarization beam splitting element 22 and the S-type polarized light is reflected by the polarization beam splitting element 22 .

[0057] In some embodiments, Figure 3 As shown, the beam splitting and reflecting assembly 2 includes a beam sampling mirror 24, which is disposed between the light source 1 and the energy detection unit 23, and a flat lens may be selected. The beam sampling mirror 24 is configured to separate a sample beam from the laser and transmit the sample beam to the energy detection unit 23 for detection by the energy detection unit 23. The incident surface of the beam sampling mirror 24 is coated with a coating, which can separate the sample beam incident into the beam sampling mirror 24 according to a preset ratio. In some embodiments, the energy ratio of the sample beam to the beam incident into the beam sampling mirror 24 is 1%-10%.

[0058] In some embodiments, the installation of the beam sampling mirror 24 is at a certain angle to the propagation direction of the light beam incident into the beam sampling mirror 24, and the beam sampling mirror 24 can transmit part of the light and reflect another part of the light to the energy detection unit 23. In other words, the beam sampling mirror 24 can reflect the separated sample light beam, deflect its propagation direction to the energy detection unit 23, and the rest of the light beam incident into the beam sampling mirror 24 continues to propagate through the beam sampling mirror 24. The energy detection unit 23 can detect the energy value of the sample light beam, and thus calculate the energy value of the light beam incident into the beam sampling mirror 24 according to a preset ratio, thereby realizing its energy detection function.

[0059] In some embodiments, see Figure 1-Figure 3 As shown, the laser generator 100 also includes a first reflector 4, which is arranged between the beam splitting and reflecting component 2 and the diffusion component 3, and can reflect the light emitted from the beam splitting and reflecting component 2 to the diffusion component 3, so that the light path is bent, or the optical axis is deflected, thereby achieving the effect of reducing the overall structure of the laser generator 100.

[0060] In some embodiments, see Figure 3 As shown, the beam splitting and reflecting assembly 2 further includes a second reflector 5, and the second reflector 5 and the light source 1 are respectively arranged on opposite sides of the beam sampling mirror 24. In other words, the second reflector 5 is arranged between the beam sampling mirror 24 and the first reflector 4. The beam sampling mirror 24 can transmit part of the light and reflect another part of the light to the energy detection unit 23. Correspondingly, the second reflector 5 is used to reflect at least part of the light transmitted by the beam sampling mirror 24 to the first reflector 4.

[0061] It can be understood that in this embodiment, the role of the second reflector 5 is to cooperate with the first reflector 4 to achieve the folding of the optical path, thereby realizing the miniaturized design of the laser generator 100 of the present application. In some embodiments, the second reflector 5 deflects the direction of the light beam passing through the beam sampling mirror 24 by 90° and then propagates it to the first reflector 4, and the first reflector 4 deflects the light beam by 90° and propagates it to the subsequent optical path. The beam splitting and reflecting component 2 adopts the arrangement of the beam sampling mirror 24 and the second reflector 5, which relatively reduces the cost of the beam splitting and reflecting component 2 and is suitable for low-cost solutions.

[0062] See also Figure 1-Figure 3As shown, the diffusion component 3 includes a diffuser 31 and a focusing lens 32. The diffuser 31 is used to homogenize the light, or to degrade the quality of the light beam passing through the diffuser 31, so that the light beam intensity distribution in space is uniform, thereby avoiding excessive light intensity from damaging the optical fiber 7. The focusing lens 32 is arranged on the side of the diffuser 31 away from the beam splitting and reflecting component 2 in the direction of light beam propagation. The light beam passing through the diffuser 31 is focused by the focusing lens 32. It can be understood that the focusing lens 32 is used to focus the light beam incident to the focusing lens 32, thereby changing the cross-sectional diameter of the light beam, and can reduce the cross-sectional diameter of the light beam so that the light beam emitted from the focusing lens 32 is adapted to the diameter of the incident end face of the optical fiber 7, thereby improving the transmission efficiency. It can be understood that the arrangement of the diffuser 31 and the focusing lens 32 can reduce the risk of damage to the transmission optical fiber 7 and improve the transmission efficiency.

[0063] In some embodiments, the diffuser 31 may be an optical device such as a microlens array, an aspherical lens, or a diffractive optical element, etc. The focusing lens 32 may be an optical device such as a plano-convex lens or a biconvex lens, etc.

[0064] In some embodiments, the light source 1 is configured to be a laser capable of emitting linearly polarized light with a wavelength between 200nm and 400nm, a pulse width between 5nsec and 15nsec, a repetition frequency of 1-400HZ, and a single pulse energy of not less than 100mJ. A solid laser or a gas laser can be selected. Thus, the beam splitting reflection component 2 and the diffusion component 3 are combined to generate a short wavelength, a short pulse width, and an output light that is easy to transmit through the optical fiber 7 to avoid damaging the optical fiber 7, and the output light is transmitted through the optical fiber 7 into the tissue or part to be ablated, such as the diseased tissue in the blood vessel, to ablate the diseased tissue in the blood vessel, and achieve the therapeutic purpose of opening the blood vessel and restoring blood supply.

[0065] In some embodiments, the laser is configured to produce a laser beam that satisfies a laser beam quality factor M 2 >5 laser, see Fig. 9 As shown, Fig. 9 The laser beam quality factor M of the beam input to the diffuser 31 for this application is 2 The energy distribution of the light beam output by the diffuser 31 in space when the value of is different. Fig. 9 It can be seen that when M 2 =X, the energy of the light beam emitted from the diffuser 31 is distributed more concentratedly in space. 2 Increase to M 2 =2*X, the energy of the light beam emitted from the diffuser 31 is greater than that of M 2 =X, the energy of the light beam emitted from the diffuser 31 is more uniformly distributed in space. 2 Gradually increase to M 2=4*X,M 2 =8*X, the energy of the light beam emitted from the diffuser 31 is also more uniformly distributed in space. It can be understood that the larger the laser beam quality factor value of the light beam entering the diffuser 31, the more uniform the energy of the light beam emitted from the diffuser 31 is distributed in space, so the present application selects a laser beam quality factor M that can emit 2 >5, thereby improving the homogenization effect of the diffuser 31 on the laser beam and avoiding damage to the optical fiber 7.

[0066] In some embodiments, see Figure 1-Figure 5 As shown, Figure 4 for Figure 1 Another structural schematic diagram of the laser generator 100 shown in FIG. Figure 5 for Figure 3 Another structural schematic diagram of the laser generator 100 is shown. The laser generator 100 also includes an indicator light source component 6, which is arranged between the diffusion component 3 and the optical fiber 7, and is used to generate visible light with the same optical path as the laser. It can be understood that the wavelength of the laser emitted by the light source 1 is between 200nm-400nm, most of which is located in the spectral range of invisible light, and the optical path of the visible light is the same as the optical path of the laser emitted by the light source 1, so that the indicator light source component 6 can play an indicating role, showing the propagation path of the laser emitted by the light source 1 from the diffusion component 3 and transmitted through the optical fiber 7 to the patient's tissue to be ablated, thereby providing medical staff using the laser generator 100 of the present application with information such as whether it is used normally or whether the optical fiber 7 can transmit the laser normally, and can determine the irradiation position of the light beam emitted after passing through the optical fiber 7.

[0067] In some embodiments, continue to refer to Figure 1-Figure 5 As shown, the indicator light source assembly 6 includes a beam combining lens 61 and an indicator light source 62. The indicator light source 62 is used to emit visible light. For example, the indicator light source 62 can use a laser that can generate a continuous laser with a wavelength of 400nm to 780nm. The light beam within this wavelength range can be recognized by the human eye. The beam combining lens 61 is arranged between the diffusion component 3 and the indicator light source 62, and is configured to be able to combine the visible light and the light passing through the diffusion component 3 and then emit them, that is, the visible light emitted by the indicator light source 62 has the same optical path as the light of the laser emitted by the light source 1 after being emitted from the diffusion component 3. It can be understood that while the indicating light source assembly 6 plays an indicating role, the indicating light source 62 is arranged at a position that will not block the propagation path of the laser light beam passing through the diffusion assembly 3, and the beam combining lens 61 is arranged so that the invisible light wavelength can pass through the beam combining lens 61 while the visible light wavelength will be reflected after passing through the beam combining lens 61. Therefore, the use of the beam combining lens 61 can change the direction of the visible light emitted by the indicating light source 62, so that it coincides with the optical path of the light beam emitted by the laser from the light source 1 after being emitted from the diffusion assembly 3, so as to achieve the indicating effect.

[0068] In some embodiments, see Figure 1-Figure 3 As shown, the beam combining lens 61 can be configured as a flat optical lens, see Figure 4-Figure 5 As shown, the beam combining lens 61 can also be set as a beam combining cubic prism, which is composed of two identical prisms with isosceles right triangle cross sections, whose hypotenuses overlap and are combined into a cubic prism with a square cross section, wherein the combined surface can be coated to achieve the function of transmitting invisible light wavelengths and reflecting visible light wavelengths. In some embodiments, the beam combining cubic prism can be set in a non-adhesive bonding manner to meet the needs of transmitting high peak power pulsed lasers in this application. It can be understood that the beam combining cubic prism is easy to install and easy to calibrate the optical path, and can avoid the deviation of light before and after passing through the beam combining cubic prism, while the flat optical lens has the advantage of low cost. You can choose to use a beam combining cubic prism or a flat optical lens according to actual needs.

[0069] In some embodiments, see Figure 6 As shown, the polarization splitter element 22 can be set as a cubic polarization splitter and the beam combining lens 61 can be set as a beam combining cubic prism according to the needs, so as to improve the convenience of installation of the laser generator 100 and the convenience of optical path calibration, and avoid optical path deviation.

[0070] The ablation system provided by the present application performs ablation treatment on the patient's tissue to be ablated by using a laser generator 100 to generate a laser with a short wavelength and a short pulse width. The laser energy with a short wavelength and a short pulse width has a high peak power, and the risk of damaging the incident end face of the optical fiber 7 is very high. The laser generator 100 of the present application modulates the laser emitted by the light source 1 in space or through the beam splitting reflection component 2 and the diffusion component 3, thereby avoiding damage to the incident end face of the optical fiber 7 and improving the beam quality of the output light of the laser generator 100. At the same time, the beam splitting reflection component 2 can realize the functions of beam sampling and energy regulation, thereby improving the convenience of use of the ablation system of the present application.

[0071] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0072] The above-mentioned embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application shall be subject to the attached claims.

Claims

1. A laser generator for laser ablation, characterized in that: The laser generator comprises: A light source for emitting laser light; A beam splitting and reflecting component is provided at the light emitting side of the light source, and the beam splitting and reflecting component is configured to be able to adjust the energy of the laser passing through the beam splitting and reflecting component; and A diffusion component is arranged on the exit path of the beam splitting reflection component, and the diffusion component is configured to be able to homogenize the beam intensity distribution of the laser.

2. The laser generator according to claim 1, characterized in that: The laser generator also includes a first reflector, which is arranged between the beam splitting reflector component and the diffuser component. The first reflector is inclined to the light emitting direction of the beam splitting reflector component and the light incident direction of the diffuser component, and can reflect at least part of the light emitted from the beam splitting reflector component to the diffuser component.

3. The laser generator according to claim 1, characterized in that: The light source is used to emit linearly polarized light, and the beam splitting reflection component includes an energy detection unit, which can receive part of the light.

4. The laser generator according to claim 3, characterized in that: The beam splitting and reflecting component comprises a polarization beam splitting element, which is arranged at the light-emitting side of the light source and is used to split the light into two polarized lights with different polarization state directions and respectively emit them to the energy detection unit and the diffusion component.

5. The laser generator according to claim 3, characterized in that: The beam splitting and reflecting component comprises a beam sampling mirror, which is arranged between the light source and the energy detection unit, and is configured to separate a sample beam from the laser and transmit the sample beam to the energy detection unit.

6. The laser generator according to claim 4, characterized in that: The beam splitting and reflecting assembly further comprises a half-wave plate and a driving element. The half-wave plate is arranged between the polarization beam splitting element and the light source. The driving element can drive the half-wave plate to rotate around the optical axis of the light source.

7. The laser generator according to claim 6, characterized in that: The beam splitting reflection component also includes a control element, which is communicatively connected to the energy detection unit and the driving element, and is used to control the driving element according to the detection result of the energy detection unit to adjust the rotation angle of the half-wave plate relative to the optical axis.

8. The laser generator according to claim 2, characterized in that: The beam splitting reflection assembly also includes a second reflector, an energy detection unit and a beam sampling mirror. The second reflector and the light source are respectively arranged on two opposite sides of the beam sampling mirror. The beam sampling mirror can transmit part of the light and reflect another part of the light to the energy detection unit. The second reflector is used to reflect at least part of the light transmitted by the beam sampling mirror to the first reflector.

9. The laser generator according to claim 1, characterized in that: The diffusion component includes a diffuser and a focusing lens, and the diffuser is used to homogenize light; The focusing lens is arranged on a side of the diffuser away from the beam splitting reflection component in the propagation direction of the light path.

10. The laser generator according to claim 1, characterized in that: The laser generator comprises an indicating light source component, which is arranged on the light-emitting side of the diffusion component and is used to generate visible light with the same optical path as the laser.

11. The laser generator according to claim 10, characterized in that: The indicator light source assembly comprises a beam combining lens and an indicator light source, and the indicator light source is used to emit the visible light; The beam combining lens is disposed between the diffusion component and the indication light source, and is configured to combine the visible light and the light passing through the diffusion component and then emit the combined light.

12. The laser generator according to claim 1, characterized in that: The light source is configured to emit a laser beam with a wavelength between 200nm and 400nm, a pulse width between 5nsec and 15nsec, and a laser beam quality factor M 2 >5 lasers.

13. An ablation system, characterized in that: The invention comprises the laser generator and the ablation catheter according to any one of claims 1 to 9, wherein the ablation catheter comprises an optical fiber.

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