Scalp care composition and application thereof

By using bacterial agents such as selenium disulfide and pirocorone ethanolamine salt in scalp care compositions, combined with plant ingredients such as patchouli extract, to form a composite anti-dandruff composition, the existing anti-dandruff products have been solved in a single function and The problem of dandruff cannot be cured, and it can achieve multi-functional effects of removing dandruff and relieving itching, soothing and controlling oil.

CN119454483APending Publication Date: 2025-02-18MENTHOLATUM (CHINA) PHARM CO LTD
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Patent Information

Application Number
CN202411778263.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-05
Publication Date
2025-02-18

AI Technical Summary

Technical Problem

When dealing with scalp microecological balance, existing anti-dandruff products have a single function and cannot cure dandruff, and the treatment of dry and white shavings is not effective.

Method used

Using a scalp care composition, including the fungicide selenium disulfide and piroctone ethanolamine salt, combined with patchouli extract, matrine, hydroxyphenylpropionamide benzoic acid, salicylic acid and witch hazel extract The components of the composition form a composite anti-dandruff composition, which has the effects of anti-dandruff and anti-itchi, soothe and oil-control.

Benefits of technology

This composition can effectively inhibit the reproduction of Malassezia, balance scalp microorganisms, reduce inflammatory responses, promote keratin renewal, control sebum production, significantly improve scalp health, and is better than the anti-dandruff, oil control and anti-inflammatory and soothing effects of commercially available products.

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Abstract

The invention relates to the technical field of daily chemical products, in particular to a scalp care composition and application thereof. From the perspective of scalp care, selenium disulfide and piroctone olamine salt are taken as bactericides and compounded with bactericidal and anti-dandruff components to form the organic and integrated anti-dandruff and scalp conditioning composition, and the composition has the effects of removing dandruff, relieving itching, soothing and controlling oil and can effectively relieve the problems of dry dandruff and fungal dandruff. The scalp care composition is added into the shampoo, serves as a main component of the multi-effect repairing and dandruff removing shampoo, can effectively solve the problems of oily dandruff, dry dandruff, scalp itching, scalp hair greasy, scalp sub-health and the like, and has the effects of reducing scalp inflammatory response, promoting updating of scalp cutin, inhibiting generation of scalp redundant sebum and the like; the nursing dimension is more comprehensive, and the application range is wider.
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Description

Technical Field

[0001] The invention relates to the technical field of daily chemical products, and in particular to a scalp care composition and application thereof. Background Art

[0002] Dandruff is a common scalp and hair problem, medically known as "pityriasis capitis", and its main cause is the disturbance of the scalp's microecological balance. This can be traced back to genes and individual immunity from the inside, and to the use of topical medications or personal care products from the outside. The use of topical medications or personal care products focuses on dealing with the scalp's microecological balance, including the scalp's skin barrier function, cell physiological effects, microbial distribution and other factors. These aspects may be inducements to each other, or they may occur at the same time, which is closely related to the individual's age, living habits and environment, and physical health status. Dandruff generally begins in adolescence, and 50% of adults are troubled by dandruff, which is a key issue for the pharmaceutical and daily chemical industries.

[0003] Among them, microbial balance is the most direct problem. There are many kinds of microorganisms distributed on the human scalp, mainly composed of Staphylococcus, Propionibacterium and Malassezia. The over-proliferation of Malassezia is the key factor in the dandruff problem. It belongs to the fungus with lipase activity. When the scalp secretes too much sebum, the Malassezia on the scalp decomposes the triglycerides and saturated fatty acids in the sebum into unsaturated fatty acids by secreting lipase. Unsaturated fatty acids are pro-inflammatory and can penetrate into the stratum corneum of the scalp, which can not only cause itching of the scalp, but also allow calcium ions to flow into the scalp cells, which will further cause the scalp keratinocytes to over-keratinize, leading to abnormal scalp keratin and accelerated dandruff. Along with the process of dandruff production, the scalp will also have problems such as itching, greasiness and odor. The itching of the scalp is related to NK1&PAR-2 ​​receptors, which will trigger the release of histamine and cause scalp discomfort. In addition, if the scalp is in a dry state for a long time, or the microecology is unbalanced and the hydration level of the cuticle is unhealthy, it will easily cause the cuticle to fall off abnormally, accompanied by inflammation, which aggravates this phenomenon. We call it white flakes or dry flakes.

[0004] Common anti-dandruff products on the market mainly achieve dandruff removal through antibacterial means. The antibacterial agents used mainly include pyrithione zinc, piroctone olamine salt, selenium disulfide, climbazole, ketoconazole and salicylic acid. The overall design of the formula lacks the concept of all-round scalp care, such as dry dandruff repair and scalp care. The functions are relatively single and have a certain anti-dandruff effect, but they often cannot cure the disease and dandruff will often come back. Summary of the invention

[0005] The purpose of the present invention is to overcome the shortcomings of the prior art and provide a scalp care composition, which has the effects of removing dandruff, relieving itching, soothing and controlling oil, and can be used as the main component of shampoo.

[0006] To achieve the above object, the technical solution adopted by the present invention is:

[0007] In a first aspect, the present invention provides a scalp care composition, comprising the following components in parts by weight: 0.001-2 parts of a fungicide, 0.001-5 parts of component A, 0.00001-5 parts of component B, 0.001-5 parts of component C, and 0.001-5 parts of component D; the fungicide comprises selenium disulfide and / or piroctone olamine salt; the component A comprises at least one of patchouli extract, matrine, hyaluronic acid, and niacinamide; the component B comprises at least one of hydroxyphenylpropionamide benzoic acid, Centella asiatica extract, bisabolol, dipotassium glycyrrhizate, and soybean fermentation product; the component C comprises salicylic acid and / or fruit acid; the component D comprises witch hazel extract and / or zinc pyrrolidone carboxylate.

[0008] The present invention takes selenium disulfide and piroctone olamine salt as bactericides, and compound anti-dandruff ingredients to form an organic anti-dandruff and scalp conditioning composition from the perspective of scalp care, which has the effects of anti-dandruff and antipruritic, soothing and controlling oil, and can effectively alleviate the problems of dry dandruff and fungal dandruff. From the perspective of antibacterial, the present invention compounded each component, which can effectively inhibit the reproduction of Malassezia, balance the microbial balance, and has good anti-inflammatory, oil-control and antioxidant effects, helping to restore the health of the scalp. The composite plant component can effectively assist in oil control, inhibit the production of excess oil on the skin, and help to reduce the production of dandruff. At the same time, inflammatory reaction is also a key factor in causing dandruff and itching. The present invention selects efficient anti-inflammatory ingredients to solve problems such as itching, so that the anti-dandruff effect is more obvious, and compounding has organic acid components that promote keratin renewal and active ingredients with soothing and moisturizing effects, so that the scalp returns to a young and healthy state. For the care of the scalp barrier, the present invention adds oil-control ingredients and moisturizing and repairing ingredients, so that the scalp is in a healthy state of water-oil balance. The present invention starts with the various causes of dandruff, not only can effectively solve oily dandruff, but also effectively treat dry dandruff and white dandruff; starting from scalp care, it can also solve the problems of oil-water imbalance, abnormal keratin and itching of the scalp. In the scalp care composition, selenium disulfide has multiple effects, which can play an antifungal role, reduce desquamation and inhibit epidermal proliferation and reduce epidermal replacement rate by reducing the colonization of Malassezia. Piroctone olamine (OCT) is a pyridine derivative, which has a good antibacterial effect on Gram-positive bacteria and Gram-negative bacteria. The main action point is the cell membrane, which inhibits the transport of substrates such as leucine, causes cell membrane changes, and eventually causes cell rupture, thereby playing an antibacterial and bactericidal effect. Relative to bacteria, OCT has a better antibacterial effect on fungi, can form a complex with iron ions, inhibit the mitochondrial energy metabolism of fungi, and then play an inhibitory and bactericidal effect. In addition, it also has an antioxidant effect and reduces local inflammatory reactions. The present invention has a more comprehensive bactericidal effect by compounding the two components. Patchouli plants are rich in oligosaccharides and proteoglycans, which can control cell migration, enhance the barrier function of the scalp, rebalance sebum production, and help restore the microbiome of a healthy scalp to reduce scalp dandruff. Matrine has a strong antibacterial ability against Malassezia and has a strong anti-dandruff ability. Panthenol, hyaluronic acid or niacinamide can enhance the hydration capacity of the stratum corneum and help the scalp retain moisture. Hydroxyphenylpropionamide benzoic acid is a substance that mimics the active ingredients of oats, which can regulate NK1&PAR-2 ​​receptors involved in itching sensation, inhibit histamine release, and reduce itching reactions. Soybean fermentation products can restore the level of antimicrobial peptides in the scalp microbiome, thereby reducing inflammation. Centella asiatica, bisabolol and dipotassium glycyrrhizinate can inhibit allergic reactions caused by histamine, solving imbalances such as itching of the scalp from all dimensions. Salicylic acid or fruit acid can penetrate the stratum corneum, soften the cuticle, and promote cuticle renewal.Witch hazel contains a variety of tannins, which have soothing, astringent and antibacterial effects; the main function of zinc pyrrolidonecarboxylic acid is 5α-reductase, which regulates sebum production and reduces lipase activity and oxidative inflammation.

[0009] Preferably, the following components are included in parts by weight: 0.1-2 parts of fungicide, 0.01-3.01 parts of component A, 0.01-3 parts of component B, 0.01-1 parts of component C, and 0.01-3 parts of component D.

[0010] Preferably, the fungicide is selenium disulfide and piroctone olamine salt; the component A is patchouli extract and matrine; the component B is hydroxyphenylpropionamide benzoic acid; the component C is salicylic acid; and the component D is witch hazel extract.

[0011] Preferably, the scalp care composition comprises the following components in parts by weight: 0.5 parts of selenium disulfide, 0.5 parts of piroctone olamine salt, 0.01 parts of patchouli extract, 0.01 parts of matrine, 0.1 parts of hydroxyphenylpropionamide benzoic acid, 0.2 parts of salicylic acid, and 0.1 parts of witch hazel extract.

[0012] In a second aspect, the present invention provides use of the scalp care composition in preparing scalp care products.

[0013] In a third aspect, the present invention provides a scalp care product, comprising the scalp care composition described above.

[0014] Preferably, the scalp care composition is added in an amount of 2-10% in the scalp care product.

[0015] Preferably, the scalp care composition is added in an amount of 1.42% in the scalp care product.

[0016] Preferably, the scalp care product further comprises auxiliary materials acceptable in daily chemical products.

[0017] Preferably, the auxiliary materials include moisturizers, thickeners, conditioners, detergents, preservatives, pH adjusters, and chelating agents.

[0018] Preferably, the moisturizer includes at least one of butylene glycol and glycerin; the thickener includes acrylate copolymer; the conditioner includes polyquaternium-10; the cleanser includes at least one of cocamidopropyl betaine and sodium cocoyl glutamate; the preservative includes phenoxyethanol; the pH adjuster includes citric acid; and the chelating agent includes disodium EDTA.

[0019] The beneficial effects of the present invention are:

[0020] The scalp care composition of the present invention uses selenium disulfide and / or piroctone olamine salt as bactericides, and patchouli extract, matrine, etc. as main antibacterial and antidandruff ingredients, which can reduce the usage of a single antidandruff agent, has the functions of killing fungi, balancing the balance of head microorganisms, and enhancing the scalp barrier, and can effectively alleviate the problems of dry dandruff and fungal dandruff. The composition is then compounded with other components to obtain a combined antidandruff composition, which is multifunctionally designed from the perspective of scalp care, and achieves an organically integrated antidandruff and scalp conditioning effect in terms of reducing scalp inflammatory reactions, promoting the renewal of scalp keratin, and inhibiting the production of excess scalp sebum, etc., and has antidandruff, oil control, and anti-inflammatory soothing effects that are significantly better than those of commercially available products.

[0021] The multi-effect repairing anti-dandruff shampoo prepared by the present invention can effectively treat oily dandruff and dry dandruff, itchy scalp, greasy scalp and hair, sub-healthy scalp and other problems, has a wider range of applications and a more comprehensive care dimension. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 The results are as follows: the change in the amount of dandruff after the subjects used the shampoo of Example 2.

[0023] Figure 2 This is a partial picture showing the occurrence of dandruff after a subject used the shampoo of Application Example 2.

[0024] Figure 3 The results of the soothing effect evaluation after the test product was used by the subjects. DETAILED DESCRIPTION

[0025] In order to better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments.

[0026] The sources of the raw materials and reagents used in the present invention are:

[0027]

[0028]

[0029] Embodiment 1:

[0030] An embodiment of the scalp care composition of the present invention; the scalp care composition comprises the following components in parts by weight: 0.01 parts of selenium disulfide, 0.99 parts of piroctone olamine salt, 0.01 parts of patchouli extract, 0.01 parts of matrine, 0.1 parts of hydroxyphenylpropionamide benzoic acid, 0.2 parts of salicylic acid, and 0.1 parts of witch hazel extract.

[0031] Embodiment 2:

[0032] An embodiment of the scalp care composition of the present invention; the scalp care composition comprises the following components in parts by weight: 0.5 parts of selenium disulfide, 0.5 parts of piroctone olamine salt, 0.01 parts of patchouli extract, 0.01 parts of matrine, 0.1 parts of hydroxyphenylpropionamide benzoic acid, 0.2 parts of salicylic acid, and 0.1 parts of witch hazel extract.

[0033] Embodiment 3:

[0034] An embodiment of the scalp care composition of the present invention; the scalp care composition comprises the following components in parts by weight: 1 part of selenium disulfide, 1 part of piroctone olamine salt, 3 parts of patchouli extract, 0.01 part of matrine, 0.01 part of hydroxyphenylpropionamide benzoic acid, 0.01 part of salicylic acid, and 3 parts of witch hazel extract.

[0035] Embodiment 4:

[0036] An embodiment of the scalp care composition of the present invention; the scalp care composition comprises the following components in parts by weight: 0.05 parts of selenium disulfide, 0.05 parts of piroctone olamine salt, 1 part of patchouli extract, 0.01 parts of matrine, 3 parts of hydroxyphenylpropionamide benzoic acid, 1 part of salicylic acid, and 0.01 parts of witch hazel extract.

[0037] Embodiment 5:

[0038] An embodiment of the scalp care composition of the present invention; the scalp care composition comprises the following components in parts by weight: 0.001 parts of selenium disulfide, 0.001 parts of patchouli extract, 0.00001 parts of hydroxyphenylpropionamide benzoic acid, 0.001 parts of salicylic acid, and 0.001 parts of witch hazel extract.

[0039] Embodiment 6:

[0040] An embodiment of the scalp care composition of the present invention; the scalp care composition comprises the following components in parts by weight: 1 part of selenium disulfide, 1 part of piroctone olamine salt, 0.001 part of patchouli extract, 0.001 part of hyaluronic acid, 4.998 parts of niacinamide, 0.001 part of hydroxyphenylpropionamide benzoic acid, 0.001 part of bisabolol, 0.001 part of dipotassium glycyrrhizinate, 0.001 part of soybean fermentation product, 4.996 parts of Centella asiatica extract, 3 parts of salicylic acid, 2 parts of fruit acid, 0.001 part of zinc pyrrolidonecarboxylate, and 4.999 parts of witch hazel extract.

[0041] Embodiment 7:

[0042] An embodiment of the scalp care composition of the present invention; the scalp care composition comprises the following components in parts by weight: 0.1 part of selenium disulfide, 0.01 part of patchouli extract, 0.01 part of hydroxyphenylpropionamide benzoic acid, 0.01 part of salicylic acid, and 0.01 part of witch hazel extract.

[0043] Embodiment 8:

[0044] An embodiment of the scalp care composition of the present invention; the scalp care composition comprises the following components in parts by weight: 1 part of selenium disulfide, 1 part of piroctone olamine salt, 0.01 part of patchouli extract, 2.99 parts of niacinamide, 0.01 part of hydroxyphenylpropionamide benzoic acid, 2.99 parts of Centella asiatica extract, 1 part of salicylic acid, and 3 parts of witch hazel extract.

[0045] Comparative Example 1:

[0046] A comparative example of the scalp care composition of the present invention; the difference between this comparative example and Example 2 is that: this comparative example does not add patchouli extract and matrine, that is, component A, and is replaced by water in equal parts by weight.

[0047] Comparative Example 2:

[0048] A comparative example of the scalp care composition of the present invention; the difference between this comparative example and Example 2 is that: this comparative example does not add hydroxyphenylpropionamide benzoic acid, that is, component B, and is replaced by an equal weight portion of water. Comparative Example 3:

[0049] A comparative example of the scalp care composition of the present invention; the difference between this comparative example and Example 2 is that salicylic acid, namely component C, is not added in this comparative example, and is replaced by water in equal parts by weight.

[0050] Comparative Example 4:

[0051] A comparative example of the scalp care composition of the present invention; the difference between this comparative example and Example 2 is that: this comparative example does not add witch hazel extract, namely component D, but replaces it with water in equal parts by weight.

[0052] Application Example 1:

[0053] An application embodiment of the scalp care product of the present invention is specifically a multi-effect repairing and anti-dandruff shampoo; the shampoo includes the scalp care composition of the embodiment; the formula of the shampoo is shown in Table 1.

[0054] Table 1

[0055]

[0056]

[0057] The preparation method of the multi-effect repairing anti-dandruff shampoo comprises the following steps:

[0058] (1) adding appropriate amount of water, disodium EDTA, cocamidopropyl betaine, sodium cocoyl glutamate, and acrylate copolymer in a container in sequence, stirring and dissolving them uniformly to obtain a mixture A;

[0059] (2) adding polyquaternium-10, selenium disulfide, piroctone olamine salt and 2.5% glycerin in the scalp care composition to the mixture A, and stirring the mixture using a high-speed disperser to obtain a mixture B;

[0060] (3) Phenoxyethanol, the remaining glycerin, the remaining scalp care composition, butylene glycol, and water are added to the mixture B, and the mixture is stirred and dispersed to be uniformly dissolved; and the pH value is adjusted to 5.0-7.0 with citric acid to obtain the multi-effect repairing anti-dandruff shampoo.

[0061] Application Example 2:

[0062] An application embodiment of the scalp care product of the present invention is specifically a multi-effect repairing anti-dandruff shampoo; the difference between this application embodiment and application embodiment 1 is only that 1.42% of the scalp care composition of embodiment 1 contained in application embodiment 1 is replaced with 1.42% of the scalp care composition of embodiment 2, and the remaining components and their contents are the same as those in application embodiment 1.

[0063] The preparation method of the shampoo is the same as that of Application Example 1.

[0064] Application Comparative Example 1:

[0065] An application comparison example of the scalp care product of the present invention is specifically a multi-effect repairing anti-dandruff shampoo; the difference between this application comparison example and application example 1 is only that 1.42% of the scalp care composition of example 1 contained in application example 1 is replaced by 1.42% of the scalp care composition of comparison example 1, and the remaining components and their contents are the same as those in application example 1.

[0066] The preparation method of the shampoo is the same as that of Application Example 1.

[0067] Application Comparative Example 2:

[0068] An application comparison example of the scalp care product of the present invention is specifically a multi-effect repairing anti-dandruff shampoo; the difference between this application comparison example and application example 1 is only that 1.42% of the scalp care composition of Example 1 contained in application example 1 is replaced by 1.42% of the scalp care composition of comparison example 2, and the remaining components and their contents are the same as those in application example 1.

[0069] The preparation method of the shampoo is the same as that of Application Example 1.

[0070] Application Comparative Example 3:

[0071] An application comparison example of the scalp care product of the present invention is specifically a multi-effect repairing anti-dandruff shampoo; the difference between this application comparison example and application example 1 is only that 1.42% of the scalp care composition of Example 1 contained in application example 1 is replaced by 1.42% of the scalp care composition of comparison example 3, and the remaining components and their contents are the same as those in application example 1.

[0072] The preparation method of the shampoo is the same as that of Application Example 1.

[0073] Application Comparative Example 4:

[0074] An application comparison example of the scalp care product of the present invention is specifically a multi-effect repairing anti-dandruff shampoo; the difference between this application comparison example and application example 1 is only that 1.42% of the scalp care composition of example 1 contained in application example 1 is replaced by 1.42% of the scalp care composition of comparison example 4, and the remaining components and their contents are the same as those in application example 1.

[0075] The preparation method of the shampoo is the same as that of Application Example 1.

[0076] Test Example 1: Anti-dandruff effect test

[0077] 1. A blank shampoo without a scalp care composition was used as a base formula (Table 1), and an equal amount of the scalp care compositions prepared in Examples 1-8 and Comparative Examples 1-4 were added to prepare an anti-dandruff shampoo sample for consumer use test. Ten subjects with dandruff and itchy scalp problems were selected, and the preliminary use effect was scored after one day of use.

[0078] The scoring criteria are as follows:

[0079] (1) Anti-dandruff effect:

[0080] 5 points: significant anti-dandruff effect; 4 points: some anti-dandruff effect; 3 points: insignificant anti-dandruff effect; 2 points: no reduction in dandruff; 1 point: increased dandruff.

[0081] (2) Soothing effect:

[0082] 5 points: obvious soothing effect; 4 points: soothing effect; 3 points: not obvious soothing effect; 2 points: no soothing effect; 1 point: discomfort after use.

[0083] (3) Oil control effect:

[0084] 5 points: significant oil control effect; 4 points: some oil control effect; 3 points: no significant oil control effect; 2 points: no reduction in oil; 1 point: increased oil.

[0085] Table 2 Scoring results

[0086] Test samples Anti-dandruff effect Soothing effect Oil control effect Example 1 4.9 5.0 5.0 Example 2 5.0 5.0 5.0 Example 3 5.0 4.6 5.0 Example 4 4.8 5.0 4.8 Example 5 4.5 4.4 4.6 Example 6 5.0 5.0 5.0 Example 7 4.7 4.7 4.6 Example 8 5.0 5.0 5.0 Comparative Example 1 3.5 3.8 3.9 Comparative Example 2 3.9 2.2 3.5 Comparative Example 3 3.2 3.9 2.9 Comparative Example 4 3.9 3.4 3.2

[0087] The scoring results are shown in Table 2. Compared with Examples 1-8, the lack of any component in Comparative Examples 1-4 easily leads to an imbalance in the combination, thereby greatly reducing the efficacy of the formula. From the data comparison between the example groups, it can be seen that the allocation ratio of each group has a certain influence on the efficacy. It is not the case that the more the amount added, the better the effect. Reasonable matching between the components within the scope of the present invention can obtain better efficacy. Considering the comprehensive cost, Examples 1 and 2 are more advantageous, so Examples 1 and 2 are selected for subsequent testing.

[0088] 2. Evaluation of the anti-dandruff effect of the shampoo according to the application example:

[0089] (1) Evaluation of anti-dandruff effect

[0090] Test samples: Shampoo prepared in Examples 1-2 and Comparative Examples 1 and 4.

[0091] Each test sample was set as a group, and 10 subjects were selected for each group. The inclusion criteria were: 18-60 years old, healthy Chinese women or men; adherent dandruff score ≥ 2.5 points (0-5 points, at least 2 areas); self-reported oily scalp; dermatologists did not raise objections due to other reasons for excluding volunteers; no allergic diseases, good physical condition during the trial; no history of photosensitive diseases, no recent use of drugs that affect photosensitivity; able to read and understand all the contents of the informed consent form and voluntarily sign the informed consent form; willing to comply with all research protocol requirements; agree not to use any cosmetics, drugs and health products that may affect the results during the trial; authorized portrait use rights; other corresponding inclusion criteria. Usage: Use the test sample once a day for 28 consecutive days, and conduct satisfaction surveys on the subjects on the 3rd, 7th and 28th days respectively. The questionnaire sets very satisfied, satisfied, general, dissatisfied, and very dissatisfied options. Consumers judge the product use effect by themselves and check the corresponding results. Satisfied and very satisfied are considered to be satisfied with the anti-dandruff effect of the product. The statistical results are shown in Table 3.

[0092] Table 3 Statistical results of the anti-dandruff effect survey

[0093] Test samples Satisfaction after 3 days of use Satisfaction after 7 days of use 28 days of use satisfaction Application Example 1 80% 100% 100% Application Example 2 90% 100% 100% Application Comparative Example 1 80% 90% 100% Application Comparative Example 4 70% 80% 80%

[0094] The results show that the shampoo prepared by the application example has a better anti-dandruff effect than the shampoo prepared by the application example, and in the application example, the shampoo of application example 2 has the best anti-dandruff effect, indicating that selenium disulfide and piroctone olamine have certain anti-dandruff effects, but their effects are limited. The present invention combines selenium disulfide, piroctone olamine salt, patchouli extract and matrine to achieve synergistic effects, making the anti-dandruff effect more prominent.

[0095] (2) The shampoo prepared in Example 2 was compared with a commercial product (control group) to test the anti-dandruff effect. The anti-dandruff effect of 32 subjects using the test sample for 3 days, 7 days, and 14 days, and then stopping use for 14 days, was compared. The number of dandruff of the subjects was detected by an instrument, and the number of dandruff of the subjects before and after use was counted. The results are shown in FIG. Figure 1-3 shown.

[0096] The results are as follows Figure 1 As shown, after the subjects used the shampoo prepared in Example 2 for 3 days, 7 days, 14 days and stopped using it for 14 days, the amount of dandruff on their heads decreased by 26.30%, 37.44%, 60.64% and 45.53%, respectively, all of which were significantly decreased (p < 0.05).

[0097] Compared with the control group, after using the sample for 3 days, 7 days, 14 days and stopping use for 14 days, the difference in the decrease rate of the number of dandruff on the head (the difference between the decrease rate of Example 2 and the decrease rate of the control group) was -7.12%, -14.55%, -37.06% and -22.90%, respectively. There were significant differences (p < 0.05) after using the sample for 3 days, 7 days and stopping use for 14 days.

[0098] The antidandruff effect of the shampoo prepared in Example 2 was used by the subjects ( Figure 2 ) was better than the control group.

[0099] Test Example 2: Soothing Effect Detection

[0100] Test samples: Shampoo prepared in Application Example 2 and Application Comparative Examples 2-4.

[0101] Each test sample is set as a group, and 10 subjects are selected from each group to use the test sample once a day for 28 consecutive days. Satisfaction surveys are conducted on the subjects on the 3rd, 7th and 28th days. The questionnaire sets options such as very satisfied, satisfied, average, dissatisfied and very dissatisfied. Consumers judge the effect of the product by themselves and check the corresponding results. Those who choose satisfied and very satisfied are considered to be satisfied with the soothing effect of the product. The statistical results are as follows Figure 3 shown.

[0102] The results show that the shampoo prepared by using Example 2 has better satisfaction in all aspects of soothing dry scalp discomfort, soothing flaky scalp discomfort, soothing overall scalp discomfort, soothing scalp itching, and soothing scalp inflammation than the shampoo prepared by using the comparative example. Among the comparative examples, the soothing effect of the shampoo using comparative example 2 is better than that of the shampoo using comparative example 1, indicating that the synergistic use of hydroxyphenylpropionamide benzoic acid and witch hazel extract can have a better soothing effect.

[0103] Test Example 3: Oil Control Effect Detection

[0104] Test samples: Shampoo prepared in Application Example 2 and Application Comparative Examples 2-4.

[0105] Each test sample was set as a group, and 10 subjects were selected from each group to use the test sample once a day for 28 consecutive days. The subjects were surveyed on satisfaction at 8h, 24h and 7th day. The questionnaire set options of very satisfied, satisfied, average, dissatisfied and very dissatisfied. Consumers judged the effect of the product by themselves and checked the corresponding results. Those who chose satisfied and very satisfied were considered satisfied with the oil control effect of the product. The statistical results are shown in Table 4.

[0106] Table 4 Statistical results of oil control effect survey

[0107] Test samples 8h oil control satisfaction 24h oil control satisfaction 7-day oil control satisfaction Application Example 2 90% 80% 90% Application Comparative Example 2 90% 80% 80% Application Comparative Example 3 80% 70% 70% Application Comparative Example 4 60% 50% 50%

[0108] The results show that the oil control effect of the shampoo prepared by using Example 2 is better than that of the shampoo prepared by using the comparative example, indicating that the present invention can synergistically enhance the effect by compounding the four components of selenium disulfide, piroctone ethanolamine salt, patchouli extract and matrine, making the oil control effect more prominent. The shampoo of comparative example 3 does not contain witch hazel extract and has the worst oil control effect, indicating that witch hazel extract plays a significant role in oil control in shampoo and inhibits the production of excess sebum on the scalp.

[0109] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention rather than to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the essence and scope of the technical solution of the present invention.

Claims

1. A scalp care composition, characterized in that: The invention comprises the following components in parts by weight: 0.001-2 parts of a fungicide, 0.001-5 parts of component A, 0.00001-5 parts of component B, 0.001-5 parts of component C and 0.001-5 parts of component D; the fungicide comprises selenium disulfide and / or piroctone olamine salt; the component A comprises at least one of patchouli extract, matrine, hyaluronic acid and niacinamide; the component B comprises at least one of hydroxyphenylpropionamide benzoic acid, Centella asiatica extract, bisabolol, dipotassium glycyrrhizinate and soybean fermentation product; the component C comprises salicylic acid and / or fruit acid; the component D comprises witch hazel extract and / or zinc pyrrolidone carboxylate.

2. The scalp care composition according to claim 1, characterized in that The invention comprises the following components in parts by weight: 0.1-2 parts of a fungicide, 0.01-3.01 parts of a component A, 0.01-3 parts of a component B, 0.01-1 parts of a component C and 0.01-3 parts of a component D.

3. The scalp care composition according to claim 1, characterized in that The bactericide is selenium disulfide and piroctone olamine salt; the component A is patchouli extract and matrine; the component B is hydroxyphenylpropionamide benzoic acid; the component C is salicylic acid; and the component D is witch hazel extract.

4. The scalp care composition according to claim 3, characterized in that The scalp care composition comprises the following components in parts by weight: 0.5 parts of selenium disulfide, 0.5 parts of piroctone olamine salt, 0.01 parts of patchouli extract, 0.01 parts of matrine, 0.1 parts of hydroxyphenylpropionamide benzoic acid, 0.2 parts of salicylic acid, and 0.1 parts of witch hazel extract.

5. Use of the scalp care composition according to any one of claims 1 to 4 in preparing scalp care products.

6. A scalp care product, characterized in that: The scalp care composition comprises the scalp care composition according to any one of claims 1 to 4.

7. The scalp care product according to claim 6, characterized in that The scalp care composition is added in an amount of 2-10% in scalp care products.

8. The scalp care product according to claim 7, characterized in that The scalp care composition is added in an amount of 1.42% in the scalp care product.

9. The scalp care product according to claim 6, characterized in that The scalp care product also includes auxiliary materials acceptable in daily chemical products.

10. The scalp care product according to claim 9, characterized in that The auxiliary materials include moisturizers, thickeners, conditioners, detergents, preservatives, pH regulators, and chelating agents.

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