A composition for increasing endogenous gamma-aminobutyric acid and melatonin levels and uses thereof

By combining Panax notoginseng stem and leaf complex with γ-aminobutyric acid, L-theanine and licorice extract, the single mechanism and side effects of existing sleep aids are solved, achieving the enhancement of endogenous γ-aminobutyric acid and melatonin, improving sleep quality and having antioxidant and blood sugar stabilizing effects.

CN119454852BActive Publication Date: 2026-07-03YUNNAN AGRICULTURAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
YUNNAN AGRICULTURAL UNIVERSITY
Filing Date
2024-11-27
Publication Date
2026-07-03

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Abstract

This invention relates to a composition for increasing endogenous γ-aminobutyric acid (GABA) and melatonin levels, and its application. The composition comprises a Panax notoginseng stem and leaf complex, GABA, L-theanine, and licorice extract. The Panax notoginseng stem and leaf complex is a product obtained by alcohol extraction from Panax notoginseng stems and leaves, Gastrodia elata, Poria cocos, and Ziziphus jujuba seeds. This invention first developed a Panax notoginseng stem and leaf complex, obtained by alcohol extraction from four specific medicinal and edible materials: Panax notoginseng stems and leaves, Gastrodia elata, Poria cocos, and Ziziphus jujuba seeds. These four raw materials have a potential synergistic effect in increasing endogenous GABA and melatonin levels. This invention also creatively combines this Panax notoginseng stem and leaf complex with GABA, L-theanine, and licorice extract. The four components synergistically enhance the effect of increasing endogenous GABA and melatonin levels.
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Citation Information

Patent Citations

  • CN103169787A

  • CN107456531A