Application of fatty acid amide propyl-N, N-dimethylamine in prevention and treatment of plant diseases

By using fatty amide propyl-N,N-dimethylamine compounds, especially cocamidopropyldimethyl tertiary amine, caprenemidopropyldimethyl tertiary amine and oleic amide propyldimethyl tertiary amine amine solves the problem of lack of compounds used in the prior art for preventing and treating crop diseases, and achieves effective inhibition of a variety of crop pathogens.

CN119488099APending Publication Date: 2025-02-21CHINESE ACADEMY OF AGRI SCI LANGFANG PESTICIDE PILOT PLANT
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Patent Information

Application Number
CN202411614632.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-13
Publication Date
2025-02-21

AI Technical Summary

Technical Problem

The use of fatty amide propyl-N,N-dimethylamine compounds in the prevention and treatment of crop diseases has not been reported in the prior art.

Method used

Research has found that compounds such as cocamidopropyldimethyl tertiary amine, caprenemidopropyldimethyl tertiary amine and oleic acid amidepropyldimethyl tertiary amine have good effects on inhibiting crop diseases, and provide a kind of inclusion The fungicides of these compounds are used to prevent and treat crop diseases.

Benefits of technology

These compounds showed significant inhibitory effects on a variety of crop pathogens, especially at high concentrations, with an inhibition rate of 100%.

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Abstract

The invention discloses an application of a fatty acid amide propyl-N, N-dimethylamine compound as shown in a formula (1) in prevention and treatment of crop diseases. The structure of the compound in the formula (1) is as follows: # imgabs0 #, wherein R is C6-C22 alkyl. The compound disclosed by the invention has a relatively good prevention and treatment effect on crop diseases and has a wide application prospect.
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Description

Technical Field

[0001] The invention belongs to the field of pesticides, and specifically relates to application of a fatty amide propyl-N,N-dimethylamine compound in preventing and controlling plant diseases. Background Art

[0002] Fatty acid amide propyl dimethyl tertiary amine compounds Where R is C 6 -C 22 Alkyl is an important fine chemical intermediate that can be used as an emollient, conditioner, lubricant, plastic injection molding and pesticide emulsification. It can also be formulated with brine solution and hydrochloric acid to form a gel acid liquid system for use in oil field acid fracturing production. It has a wide range of industrial application value and a large market demand.

[0003] Document 1: CN113651709A, 2021-11-16 discloses a fatty amide propyl dimethyl tertiary amine and its preparation method and application, which discloses that fatty acid and N,N-dimethyl-1,3-propylenediamine are subjected to amidation reaction and vacuum distillation to obtain the fatty amide propyl dimethyl tertiary amine. The fatty amide propyl dimethyl tertiary amine prepared by the invention has good shear viscosity and is suitable for the field of oil field fracturing and production increase. When the fracturing fluid gel is used for oil field fracturing and production increase, it will be mixed with proppants such as quartz sand and pumped into the wellbore. If the shear viscosity is too low (less than 50mPa·s), the quartz sand is prone to sink rapidly and block the wellhead. The invention can further improve the shear viscosity of the fracturing fluid gel by optimizing parameters such as the temperature of the amidation reaction, the molar ratio of fatty acid to N,N-dimethyl-1,3-propylenediamine, the vacuum distillation temperature, and the vacuum distillation time, making it more suitable for application in the field of oil field fracturing and production increase.

[0004] Document 2: Cross-linked rheological properties of high-temperature resistant fracturing fluids modified with oleamidopropyl dimethyl tertiary amine (Wei Ping et al., Oilfield Chemistry, Vol. 37, No. 4, pp. 642-648) discloses that in order to obtain a new system of thickeners for high-temperature resistant fracturing fluids, oleamidopropyl dimethyl tertiary amine was used to hydrophobically modify hydroxypropyl guar (HPG) to obtain a new type of hydrophobically modified high-temperature resistant and shear-resistant thickener (O-HPG). Using epichlorohydrin as an intermediate carrier, oleamide long chains were linked to the active hydroxyl groups of hydroxypropyl guar molecules to obtain a new type of high-temperature resistant hydrophobically modified hydroxypropyl guar O-HPG. The gel formed by the cross-linking of the modified O-HPG has stronger elasticity and a tighter structure because the hydrophobic long chains can associate with each other. The gel formed by 0.6% O-HPG base fluid is at 200°C and a shear rate of 100s -1The retained viscosity of hydroxypropyl guar gum HPG after shearing for 1.5 hours under the same conditions was greater than 80 mPa·s, while the shear retained viscosity of hydroxypropyl guar gum HPG dropped sharply to 1 mPa·s under the same conditions. The modified O-HPG has better high temperature and shear resistance, and the system is easy to break.

[0005] Document 3: CN113292553A, 2021-08-24 discloses an aromatic thiazole-tryptamine compound and a combination agent for killing algae of Skeletonella ribes, which discloses that octanamide propyl dimethyl tertiary amine can be used as a non-ionic surfactant.

[0006] The prior art does not report that the compound of formula (1) can be used for preventing and controlling crop diseases. Summary of the invention

[0007] The present invention has found that the compound represented by formula (1) is: Where R is C 6 -C 22 Alkyl groups have a good effect in inhibiting crop diseases. Based on this, the present invention was completed.

[0008] The present invention provides a use of a fatty amide propyl-N,N-dimethylamine compound represented by formula (1) in the preparation of a compound for preventing and controlling crop diseases, wherein the compound of formula (1) has the following structure:

[0009] Where R is C 6 -C 22 alkyl.

[0010] Preferably, the compound of formula (1) is selected from one of cocoamidopropyl dimethyl tertiary amine, caprylic decanoyl dimethyl tertiary amine and oleic acid amide propyl dimethyl tertiary amine.

[0011] The present invention also discloses a bactericide, which comprises the compound represented by the above formula (1) as an effective ingredient.

[0012] Preferably, the compound of formula (1) is selected from one of cocoamidopropyl dimethyl tertiary amine, caprylic decanoyl dimethyl tertiary amine and oleic acid amide propyl dimethyl tertiary amine.

[0013] Beneficial effects of the present invention:

[0014] The compound of formula (1) of the present invention has a good effect of inhibiting crop diseases. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on rice sheath blight

[0016] Figure 2Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on potato black mole pathogen

[0017] Figure 3 Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on grape gray mold

[0018] Figure 4 Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on strawberry gray mold

[0019] Figure 5 Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on tomato gray mold

[0020] Figure 6 Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on pepper anthracnose

[0021] Figure 7 Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on strawberry anthracnose

[0022] Figure 8 Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on tomato anthracnose

[0023] Fig. 9 Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on rice blast pathogen

[0024] Fig.10 Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on Setosphaeria turcica Fig.11 Inhibitory effects of different concentrations of cocamidopropyl dimethyl tertiary amine on Blight Pathogen of Corn Fig.12 Inhibitory effects of different concentrations of octyldecylamidopropyl dimethyl tertiary amine on rice sheath blight pathogen Fig.13 Inhibitory effects of different concentrations of octyl decylamidopropyl dimethyl tertiary amine on potato black mole pathogen Fig.14 Inhibitory effects of different concentrations of octyl decylamidopropyl dimethyl tertiary amine on Botrytis cinerea Fig.15 Inhibitory effects of different concentrations of octyl-decylamidopropyl dimethyl tertiary amine on strawberry gray mold Fig.16 Inhibitory Effects of Different Concentrations of Octyldecylamidopropyl Dimethyl Tertiary Amine on Botrytis cinerea Fig.17 Inhibitory effects of different concentrations of octyl decylamidopropyl dimethyl tertiary amine on pepper anthracnose Fig.18 Inhibitory effects of different concentrations of octyldecylamidopropyl dimethyl tertiary amine on strawberry anthracnose Fig.19 Inhibitory Effects of Different Concentrations of Octyldecylamidopropyl Dimethyl Tertiary Amine on Tomato Anthracnose Fig. 20 Inhibitory Effects of Different Concentrations of Octyldecylamidopropyl Dimethyl Tertiary Amine on Rice Blast Pathogen Fig.21 Inhibitory effects of different concentrations of octyldecylamidopropyl dimethyl tertiary amine on Setophore eurybacterium turcica Fig. 22 Inhibitory effects of different concentrations of octyldecylamidopropyl dimethyl tertiary amine on Bipolaris maydis Fig.23 Inhibitory effects of different concentrations of oleamidopropyl dimethyl tertiary amine on rice sheath blight Fig.24 Inhibitory effects of different concentrations of oleamidopropyl dimethyl tertiary amine on potato black mole pathogen Fig.25 Inhibitory effects of different concentrations of oleamidopropyl dimethyl tertiary amine on Botrytis cinerea Fig.26 Inhibitory effects of different concentrations of oleamidopropyl dimethyl tertiary amine on strawberry gray mold Fig. 27 Inhibitory Effects of Different Concentrations of Oleamidopropyl Dimethyl Tertiary Amine on Botrytis cinerea Fig.28 Inhibitory effects of different concentrations of oleamidopropyl dimethyl tertiary amine on pepper anthracnose Fig.29 Inhibitory effects of different concentrations of oleamidopropyl dimethyl tertiary amine on strawberry anthracnose Fig.30 Inhibitory Effects of Different Concentrations of Oleamidopropyl Dimethyl Tertiary Amine on Tomato Anthracnose Fig.31 Inhibitory Effects of Different Concentrations of Oleamidopropyl Dimethyl Tertiary Amine on Rice Blast Pathogen Fig.32 Inhibitory effects of different concentrations of oleamidopropyl dimethyl tertiary amine on Setosphaeria turcica Fig.33 Inhibitory effects of different concentrations of oleamidopropyl dimethyl tertiary amine on Blight Pathogen of Corn DETAILED DESCRIPTION

[0025] To make the purpose, technical scheme and advantages of the embodiments of the present invention clearer, the technical scheme in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments in the present invention, all other embodiments obtained by ordinary technicians in the field without creative work are within the scope of protection of the present invention. In addition, in order to better illustrate the present invention, numerous specific details are given in the specific embodiments below. It should be understood by those skilled in the art that the present invention can be implemented without certain specific details. In certain embodiments, raw materials, auxiliary agents, methods, means, etc. known to those skilled in the art are not described in detail to highlight the main idea of ​​the present invention.

[0026] Unless otherwise expressly stated, throughout the specification and claims, the term "comprise" or its variations such as "include" or "comprising", "containing", etc. will be understood to include the stated active ingredients or components but not to exclude other active ingredients or other components.

[0027] Specifically, the present invention provides a use of a fatty amide propyl-N,N-dimethylamine compound represented by formula (1) in the preparation of a compound for preventing and controlling crop diseases. The structure of the compound of formula (1) is as follows:

[0028] Where R is C 6 -C 22 alkyl.

[0029] Preferably, the compound of formula (1) described in the above use is selected from one of cocoamidopropyl dimethyl tertiary amine, caprylic decanoyl dimethyl tertiary amine and oleic acid amide propyl dimethyl tertiary amine.

[0030] The present invention also provides a fungicide, which contains a fatty amide propyl-N,N-dimethylamine compound represented by formula (1) as an effective ingredient. Where R is C 6 -C 22 alkyl.

[0031] Preferably, the compound of formula (1) in the fungicide is selected from one of cocoamidopropyl dimethyl tertiary amine, caprylic decanoyl dimethyl tertiary amine and oleic acid amide propyl dimethyl tertiary amine.

[0032] Preferably, the above-mentioned fungicide can be prepared into a suitable formulation for pesticides, and the formulation is preferably a soluble solution, a soluble powder and a soluble granule. Further, the above-mentioned fungicide can be prepared into a suitable formulation, and the formulation is a soluble solution.

[0033] The auxiliary agent mentioned above includes one or more of solvent, emulsifier, dispersant, wetting agent, antifreeze agent, binder, defoaming agent and solid inert carrier.

[0034] Optionally, the solvent is selected from one or more of methanol, ethanol, ethylene glycol, propylene glycol, glycerol, ethylene glycol tert-butyl ether, N,N-dimethylformamide, capric amide, N-methylpyrrolidone, and dimethyl sulfoxide, preferably one or more of methanol, ethanol, capric amide and N-methylpyrrolidone.

[0035] Optionally, the emulsifier is selected from one or more of sorbitan polyoxyethylene polyoxypropylene ether, sorbitan monostearate polyoxyethylene ether, sorbitan monolaurate, sodium lauryl sulfate, alkyl glucoside, fatty alcohol polyoxyethylene ether, styrylphenol polyoxyethylene ether, and tristyrylphenol polyoxypropylene polyoxyethylene block copolymer, preferably one or more of sorbitan monostearate polyoxyethylene ether, sorbitan monolaurate, alkyl glucoside, styrylphenol polyoxyethylene ether, and tristyrylphenol polyoxypropylene polyoxyethylene block copolymer.

[0036] Optionally, the dispersant is selected from one or more of alkylnaphthalene sulfonates, alkylbenzene sulfonate calcium salts, fatty amine polyoxyethylene ethers, bis(alkyl)naphthalene sulfonate formaldehyde condensates, naphthalenesulfonic acid formaldehyde condensates, naphthalenesulfonic acid formaldehyde condensates sodium salts, alkylphenol polyoxyethylene ethers, arylphenol polyoxyethylene succinate sulfonates, octylphenol polyoxyethylene ether sulfates, polycarboxylates, lignin sulfonic acid sodium salts, alkylphenol polyoxyethylene ether formaldehyde condensate sulfates, fatty acid polyoxyethylene esters and fatty acid polyoxyethylene ethers, preferably one or more of arylphenol polyoxyethylene succinate sulfonates, naphthalenesulfonic acid formaldehyde condensates sodium salts, polycarboxylates and lignin sulfonic acid sodium salts.

[0037] Optionally, the wetting agent is selected from one or more of pull-opening powder BX, sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, agricultural milk 2000# series, sodium dioctyl sulfosuccinate, and saponin powder. Preferably, pull-opening powder BX, sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, and sodium dioctyl sulfosuccinate are selected from one or more of sodium dioctyl sulfosuccinate.

[0038] Optionally, the antifreeze agent may be one or more of ethylene glycol, 1,2-propylene glycol and glycerol, preferably ethylene glycol.

[0039] Optionally, the binder may be one or more of starch, gypsum, glucose, polyvinyl alcohol, gum arabic and dextrin, preferably glucose.

[0040] Optionally, the solid inert carrier can be one or more of clay, white carbon black, diatomaceous earth, kaolin, attapulgite, montmorillonite, bentonite, talc, light calcium carbonate, calcite, ammonium sulfate and sodium sulfate, preferably one or more of white carbon black, calcite and sodium sulfate.

[0041] Optionally, the defoaming agent is selected from silicone, C 8-10 Fatty alcohol, C 10-20 Saturated fatty acids (such as capric acid) and one or more of amides, silicone oils and silicone compounds. Silicone defoamers are preferred.

[0042] Furthermore, suitable auxiliary agents may be added according to the needs of preparing the dosage form.

[0043] Furthermore, in the above-mentioned bactericidal preparation, the fatty amide propyl-N,N-dimethylamine compound accounts for 0.1%-95% of the total weight of the preparation, preferably 1%-80%, more preferably 5%-70%.

[0044] In the present invention, there is no special requirement for the preparation method of various dosage forms, and various methods known in the art can be used, which will not be described in detail here.

[0045] The fungicide of the present invention can be used for preventing and controlling crop diseases.

[0046] The pesticide preparation of the present invention can be diluted according to actual needs when used in practice.

[0047] The crops described in the present invention are preferably rice, wheat, barley, soybean, potato, grape, strawberry, citrus, pitaya, tomato, pepper, corn, peanut, sugarcane, sorghum, rapeseed, Chinese cabbage, Chinese cabbage, kale, eggplant, and tobacco; preferably one of rice, potato, grape, strawberry, tomato, pepper and corn.

[0048] The crop diseases described in the present invention are preferably sheath blight, damping-off, brown rot, gray mold, potato black mole, anthracnose, rice blast, and corn spot, and are preferably one of rice sheath blight, grape gray mold, strawberry gray mold, tomato gray mold, pepper anthrax, tomato anthrax, rice blast, large corn spot, and small corn spot.

[0049] The following examples further illustrate the content of the present invention, but should not be construed as limiting the present invention. Unless otherwise specified in the present invention, the raw materials used can be purchased from the market.

[0050] I. Preparation Example

[0051] Example 1 Preparation of 70% Cocoamidopropyl dimethyl tertiary amine soluble solution

[0052] Calculated by mass percentage, the distribution ratio of each group is 70% cocamidopropyl dimethyl tertiary amine, 8% methanol, 5% alkyl glucoside, 5% ethylene glycol, 0.05% silicone defoamer, and water is used to make up the balance. The product is obtained after fully stirring and mixing.

[0053] Example 2 Preparation of 50% Octyldecylamide Propyl Dimethyl Tertiary Amine Soluble Solution

[0054] Calculated by mass percentage, the distribution ratio of each group is 50% octanamide propyl dimethyl tertiary amine, 10% ethanol, 15% alkyl glycoside, 5% ethylene glycol, 0.05% silicone defoamer, and water makes up the balance. The product is obtained after fully stirring and mixing.

[0055] Example 3 Preparation of 30% oleamidopropyl dimethyl tertiary amine soluble solution

[0056] Calculated by mass percentage, the distribution ratio of each group is 30% oleamidopropyl dimethyl tertiary amine, 5% capric amide, 10% alkyl glucoside, 5% sorbitan monostearate polyoxyethylene ether, 5% propylene glycol, 0.05% silicone defoaming agent, and water is used to make up the balance. The product is obtained after fully stirring and mixing.

[0057] Example 4 Preparation of 10% Cocoamidopropyl dimethyl tertiary amine soluble powder

[0058] The distribution ratio of each component is 10% cocamidopropyl dimethyl tertiary amine, 4% naphthalenesulfonic acid formaldehyde condensate sodium salt, 2% BX powder, 8% white carbon black, 0.1% silicone defoamer, and the balance is made up with Jiayi powder. The mixture is evenly mixed and crushed to obtain the product.

[0059] Example 5 Preparation of 10% Octyldecylamide Propyl Dimethyl Tertiary Amine Soluble Powder

[0060] The distribution ratio of each group is 10% octanamide propyl dimethyl tertiary amine, 5% lignin sulfonate sodium salt, 3% dioctyl sodium sulfosuccinate, 10% white carbon black, 0.1% silicone defoamer, and the remainder is supplemented with additive powder. The mixture is evenly mixed and crushed to obtain the product.

[0061] Example 6 Preparation of 10% Oleic Acid Amidopropyl Dimethyl Tertiary Amine Soluble Powder

[0062] The components are distributed in a ratio of 10% oleamidopropyl dimethyl tertiary amine, 2% naphthalenesulfonic acid formaldehyde condensate sodium salt, 2% dioctyl sodium sulfosuccinate, 10% white carbon black, 0.1% organosilicon defoaming agent, and the balance is made up of sodium sulfate. The components are mixed evenly and crushed to obtain the product.

[0063] Example 75% Preparation of Cocoamidopropyl Dimethyl Tertiary Amine Soluble Granules

[0064] Calculated by mass percentage, the distribution ratio of each component is 5% cocamidopropyl dimethyl tertiary amine, 5% naphthalenesulfonic acid formaldehyde condensate sodium salt, 3% sodium dodecyl sulfate, 5% white carbon black, 5% glucose, 0.1% silicone defoaming agent, and the balance is made up by adding benefit powder. The product is obtained after crushing, granulating and drying.

[0065] Example 8 Preparation of 10% Octyldecylamide Propyl Dimethyl Tertiary Amine Soluble Granules

[0066] Calculated by mass percentage, the distribution ratio of each group is 10% octanamide propyl dimethyl tertiary amine, 4% polycarboxylate, 5% BX powder, 10% white carbon black, 10% glucose, 0.1% organosilicon defoaming agent, and sodium sulfate makes up the balance. The product is obtained after crushing, granulating and drying.

[0067] Example 9 Preparation of 10% Oleic Acid Amidopropyl Dimethyl Tertiary Amine Soluble Granules

[0068] Calculated by mass percentage, the distribution ratio of each group is 10% oleamide propyl dimethyl tertiary amine, 5% lignin sulfonate sodium salt, 3% dioctyl sodium sulfonate succinate, 10% white carbon black, 10% glucose, 0.1% silicone defoamer, and the balance is made up by adding beneficial powder. The product is obtained after crushing, granulating and drying.

[0069] II. Bioassay Example

[0070] 1 Materials and methods

[0071] 1.1 Test strains, reagents and culture media, etc.

[0072] Test strains: 11 pathogenic fungi preserved in the laboratory, including rice sheath blight, potato black mole, grape gray mold, strawberry gray mold, tomato gray mold, pepper anthracnose, strawberry anthracnose, tomato anthracnose, rice blast, corn leaf blight and corn leaf blight, were purified and cultured for later use.

[0073] Test equipment: clean bench, autoclave, incubator, etc.

[0074] Experimental agents: cocamidopropyl dimethyl tertiary amine, caprylic decyl amide propyl dimethyl tertiary amine and oleic acid amide propyl dimethyl tertiary amine

[0075] Culture medium: Use PDA culture medium (3.0 g potato powder, 14.0 g glucose, 18.0 g agar, 1 L deionized water), mix well, sterilize at high temperature, and set aside.

[0076] 1.2 Test methods

[0077] The mycelium growth rate method was used to determine the antibacterial rate of the agent. Pour the drug-containing PDA medium into a culture dish with a diameter of 9 cm, and ensure that the working concentration of the agent on the plate is 200μg / mL, 600μg / ml and 1000μg / ml. The PDA plate without the agent was used as a blank control, and 3 replicates were set for each concentration. Inoculate an experimental activated bacterial cake with a diameter of 0.5 cm in the center of the plate and place it in a 28°C constant temperature incubator. According to the growth rate of the pathogen, choose to culture for 3-5 days. Calculate the inhibition rate of different concentrations of agents on the mycelium growth of each pathogen.

[0078] 1.3 Statistical and analytical methods

[0079] After 3-5 days of cultivation, the diameter (cm) of the bacteria in the plate was measured with a ruler, and the inhibition rate (%) of the mycelial growth of the agent under each concentration treatment was calculated.

[0080]

[0081] Where: 0.5 is the diameter of the inoculated cake, in cm.

[0082] 2 Test results

[0083] Table 1 Inhibition rate of different crop diseases by different concentrations of cocamidopropyl dimethyl tertiary amine

[0084]

[0085] Table 2 Inhibition rate of different crop diseases by different concentrations of octyl decyl amide propyl dimethyl tertiary amine

[0086]

[0087] Table 3 Inhibition rate of different crop diseases by different concentrations of oleamidopropyl dimethyl tertiary amine

[0088]

[0089] From the results in Tables 1, 2 and 3, it can be seen that cocamidopropyl dimethyl tertiary amine, octyl decyl amide propyl dimethyl tertiary amine and oleic acid amide propyl dimethyl tertiary amine have inhibitory effects on the 11 tested crop pathogenic fungi at concentrations of 200, 600 and 1000 μg / mL. The inhibition rate of cocamidopropyl dimethyl tertiary amine on strawberry gray mold and pepper anthracnose reached 100% at a concentration of 200 μg / mL. As the dosage increased, the inhibition rate of other pathogenic fungi also increased significantly. When the concentration reached 1000 μg / mL, the inhibition rate of other pathogenic fungi reached 100% except rice sheath blight. The inhibition rate of octyl decyl amide propyl dimethyl tertiary amine on tomato gray mold reached 100% at a concentration of 200 μg / mL. As the dosage increased, the inhibition rate of other pathogenic fungi also increased significantly. When the concentration reached 1000 μg / mL, the inhibition rate of all tested pathogenic fungi reached 100%. The antibacterial effect of oleamidopropyl dimethyl tertiary amine is lower than that of the other two compounds.

[0090] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. Use of the fatty amide propyl-N,N-dimethylamine compound represented by formula (1) in the preparation of a compound for preventing and controlling crop diseases, characterized in that: The structure of the compound of formula (1) is as follows: Where R is C6-C 22 alkyl.

2. The use according to claim 1, characterized in that The compound of formula (1) is selected from one of cocoamidopropyl dimethyl tertiary amine, caprylic decanoyl dimethyl tertiary amine and oleic acid amide propyl dimethyl tertiary amine.

3. The use according to claim 1 or 2, characterized in that The crops are rice, wheat, barley, soybean, potato, grape, strawberry, citrus, pitaya, tomato, pepper, corn, peanut, sugarcane, sorghum, rape, Chinese cabbage, Chinese cabbage, kale, eggplant, and tobacco; preferably, the crops are one of rice, potato, grape, strawberry, tomato, pepper, and corn.

4. The use according to claim 1, characterized in that The crop diseases are sheath blight, damping-off, brown rot, gray mold, potato black mole, anthracnose, rice blast, and corn spot, preferably one of rice sheath blight, grape gray mold, strawberry gray mold, tomato gray mold, pepper anthrax, tomato anthrax, rice blast, large corn spot, and small corn spot.

5. A bactericide, characterized in that: The active ingredient is a fatty amide propyl-N,N-dimethylamine compound represented by formula (1). Where R is C6-C 22 alkyl.

6. The fungicide according to claim 5, characterized in that The compound of formula (1) is selected from one of cocoamidopropyl dimethyl tertiary amine, caprylic decanoyl dimethyl tertiary amine and oleic acid amide propyl dimethyl tertiary amine.

7. The fungicide according to claim 5 or 6, characterized in that The pesticide can be prepared into suitable dosage forms, such as soluble solution, soluble powder and soluble granule, preferably soluble solution.

8. Use of the fungicide according to any one of claims 5 to 7 in preventing and controlling crop diseases, wherein the crops are rice, wheat, barley, soybean, potato, grape, strawberry, citrus, pitaya, tomato, pepper, corn, peanut, sugarcane, sorghum, rapeseed, Chinese cabbage, Chinese cabbage, kale, eggplant, tobacco; preferably one of rice, potato, grape, strawberry, tomato, pepper and corn.

9. The use according to claim 8, characterized in that The crop diseases are sheath blight, damping-off, brown rot, gray mold, potato black mole, anthracnose, rice blast, and corn spot, preferably one of rice sheath blight, grape gray mold, strawberry gray mold, tomato gray mold, pepper anthrax, tomato anthrax, rice blast, large corn spot, and small corn spot.

Citation Information

Patent Citations

  • Aryl thiazole-tryptamine compound for killing skeletonema costatum and combination agent thereof

    CN113292553A

  • Fatty amide propyl dimethyl tertiary amine as well as preparation method and application thereof

    CN113651709A