Foaming test device and system

Abstract

The application discloses a foaming test device and system. In the foaming test device, left / right atrial contrast test can be considered simultaneously. When the foaming test device is switched to a left atrial contrast working mode, physiological saline and a contrast agent are automatically mixed to form a left atrial contrast mixed liquid, and a left atrial contrast foaming liquid is further formed. When the foaming test device is switched to a right atrial contrast working mode, physiological saline, air and blood are automatically mixed to form a right atrial contrast mixed liquid, and a right atrial contrast foaming liquid is further formed. Through reciprocating injection of the first injector and the second injector, the efficiency of foaming of the left / right atrial contrast mixed liquid can be effectively improved, the time for forming the foaming liquid is shortened, automatic preparation of the left / right atrial contrast foaming liquid is rapidly realized, the quality, preparation efficiency and consistency of the foaming liquid are improved, and the accuracy of auxiliary screening is improved.

Description

Technical Field

[0001] This application relates to the field of medical device technology, specifically to a foaming test device and system. Background Technology

[0002] Cardiac angiography acoustics is divided into left atrial bubbling test and right atrial bubbling test. The indications for the right atrial bubbling test include: 1) screening for patent foramen ovale (PFO); 2) diagnosis of congenital vascular malformations, such as persistent left superior vena cava and pulmonary arteriovenous fistula; 3) assessment of right ventricular diameter, endocardial boundary contour, ventricular wall thickness, presence of space-occupying lesions, and valvular regurgitation; and 4) identification of the cause of hypoxemia in patients. Therefore, the right atrial bubbling test can be used as an auxiliary screening tool for various diseases.

[0003] For the right atrial bubbling test, physiological saline, purified air, and the patient's blood are separately drawn and mixed to obtain a right atrial contrast mixture. This mixture is then foamed to obtain a right atrial contrast bubbling solution, which is finally injected into the body for subsequent testing. The indications for the left atrial bubbling test include: 1) coronary artery disease; 2) heart failure; 3) intracardiac masses; and 4) auxiliary diagnosis of cardiac structural abnormalities such as hypertrophic cardiomyopathy. Therefore, the left atrial bubbling test can also be used for auxiliary screening of various diseases.

[0004] For the bubbling test of the left atrium, physiological saline and powdered contrast agent need to be mixed to obtain a left atrial contrast mixture. This mixture is then foamed to obtain a left atrial contrast bubbling fluid, which is finally injected into the body for subsequent testing. Currently, the preparation of the left atrial bubbling fluid is done manually. This method suffers from poor quality and consistency, as well as low preparation efficiency. Summary of the Invention

[0005] The main objective of this application is to provide a foaming test device and system to solve the problem that existing foaming test devices cannot automatically prepare both left atrial angiography foaming fluid and right atrial angiography foaming fluid.

[0006] According to one aspect of this application, a foaming test apparatus is provided, the foaming test apparatus comprising:

[0007] The tubing includes a first sub-tubing and a second sub-tubing. The first sub-tubing has a first end and a second end opposite to each other. The second sub-tubing has a third end and a fourth end opposite to each other. The second end is connected to an external indwelling needle. The third end is connected to the first sub-tubing. One of the first end and the fourth end is connected to a first container for containing powdered contrast agent. The other of the first end and the fourth end is connected to a second container for containing saline solution.

[0008] The first and second syringes are used to perform injection and / or extraction actions;

[0009] A first valve is disposed on the first sub-pipeline and has at least three interfaces, two of which are used to connect to the first sub-pipeline and at least one other interface is used to connect to the outside.

[0010] The second valve is disposed on the first sub-pipeline and has at least three ports, two of which are used to connect to the first sub-pipeline and at least one other port is used to connect to the first syringe.

[0011] A third valve is disposed on the first sub-pipeline and has at least three ports, two of which are used to connect to the first sub-pipeline and at least one other port is used to connect to the second syringe.

[0012] A fourth valve is provided on the first sub-pipeline and has at least three ports, two of which are used to connect to the first sub-pipeline and at least one other port is used to connect to the third end.

[0013] The foaming test device has a left atrial angiography working mode and a right atrial angiography working mode. In the left atrial angiography working mode, one of the first syringe and the second syringe transfers the saline in the second container to the first container so that the contrast agent dissolves in the saline in the first container to form a left atrial angiography mixture. The first syringe and the second syringe reciprocate to inject the left atrial angiography mixture to form a left atrial angiography bubble solution.

[0014] In the right atrial angiography working mode, one of the first syringe and the second syringe first draws physiological saline from the second container, then draws air from the outside through the first valve, and draws blood through the indwelling needle to form a right atrial angiography mixture. The first syringe and the second syringe repeatedly inject the right atrial angiography mixture to form a right atrial angiography bubble solution.

[0015] According to another aspect of this application, this application also provides a foaming testing system, the system comprising the foaming testing apparatus described in any of the preceding claims; and

[0016] A mixing device is provided to drive the first container to move, thereby dissolving the contrast agent contained in the first container in physiological saline to form a homogeneous left atrial contrast mixture, and to foam the left atrial contrast mixture; wherein the mixing device is integrated into the foaming test device, or the mixing device is independent of the foaming test device, the mixing device includes a driving member and a receiving member, the receiving member is connected to the output shaft of the driving member, the receiving member is configured to form a receiving groove for receiving the first container, and the receiving member drives the first container to reciprocate along the axial direction of the output shaft and / or reciprocate around the circumferential direction of the output shaft under the drive of the driving member.

[0017] In the foaming test device of this application, the preparation of left atrial foaming fluid can be carried out in a fully automated manner, and the prepared left atrial foaming fluid has good quality, strong consistency, and high preparation efficiency. Furthermore, the foaming test device can simultaneously perform left atrial angiography and right atrial angiography tests. When left atrial angiography is required, the foaming test device is switched to left atrial angiography mode. The foaming test device can then control the first or second syringe to automatically draw physiological saline from the second container and inject it into the first container, thereby dissolving the contrast agent in the first container into the physiological saline to form a left atrial angiography mixture. The left atrial angiography mixture is then repeatedly injected using the first and second syringes to form a left atrial angiography foaming fluid, which is finally injected into the human body. When right atrial angiography is required, the foaming test device... When the device switches to the right atrial angiography mode, the foaming test device can control the first or second syringe to automatically and sequentially draw physiological saline, purified air, and blood from the second container to form a right atrial angiography mixture. The first and second syringes are then used to repeatedly inject the right atrial angiography mixture to form a right atrial angiography foaming solution, which is then injected into the body. Furthermore, whether using a left or right atrial angiography mixture, the repeated injection using the first and second syringes effectively improves the foaming efficiency of both mixtures, thereby shortening the time required to form the foaming solution. This allows for the rapid and automated preparation of either left or right atrial angiography foaming solution, while also improving the quality, preparation efficiency, and consistency of the foaming solution, as well as enhancing the accuracy of auxiliary screening. Attached Figure Description

[0018] The accompanying drawings, which are included to provide a further understanding of this application and form part of this application, illustrate exemplary embodiments and are used to explain this application, but do not constitute an undue limitation of this application. In the drawings:

[0019] Figure 1 This is a schematic diagram of the system in one embodiment of the present application, showing the shaking device integrated on the foaming test device.

[0020] Figure 2 This is an overall schematic diagram of the system in one embodiment of the present application, showing that the shaking device is independent of the foaming test device.

[0021] Figure 3 for Figure 1 The disclosed embodiment is a schematic diagram of the pipeline connection state. The diagram shows that the first valve, the second valve, the third valve and the fourth valve are arranged sequentially from the first end to the second end of the first sub-pipeline, and the first end is connected to the second container and the fourth end is connected to the first container.

[0022] Figure 4 for Figure 1 The disclosed embodiment is a schematic diagram of the pipeline connection state. The diagram shows that the first valve, the second valve, the third valve and the fourth valve are arranged sequentially from the first end to the second end of the first sub-pipeline, and the first end is connected to the first container and the fourth end is connected to the second container.

[0023] Figure 5 This is a schematic diagram of the pipeline connection state in one embodiment of the present application. The diagram shows that the fourth valve, the first valve, the second valve and the third valve are arranged sequentially from the first end to the second end of the first sub-pipeline, and the first end is connected to the second container and the fourth end is connected to the first container.

[0024] Figure 6 This is a schematic diagram of the pipeline connection state in one embodiment of the present application. The diagram shows that the fourth valve, the first valve, the second valve and the third valve are arranged sequentially from the first end to the second end of the first sub-pipeline, and the first end is connected to the first container and the fourth end is connected to the second container.

[0025] Figure 7 This is a schematic diagram of the overall foaming test device in one embodiment of the present application, showing only the first valve, the second valve, and the third valve.

[0026] Figure 8 This is a partial structural schematic diagram of a foaming test device in one embodiment of this application. Only the first valve, the second valve, and the third valve are shown in the figure.

[0027] Figure 9This is a schematic diagram of the opening of the dust cover of the foaming test device in one embodiment of this application. Only the first valve, the second valve, and the third valve are shown in the figure.

[0028] Figure 10 This is another schematic diagram of a portion of the structure of the foaming test device in one embodiment of this application, showing only the first valve, the second valve, and the third valve.

[0029] Figure 11 This is a schematic diagram of the structure of the foaming test device and the blowing device in one embodiment of this application. Only the first valve, the second valve and the third valve are shown in the figure.

[0030] Figure 12 This is a three-dimensional schematic diagram of a shaking device in one embodiment of this application.

[0031] Figure 13 This is an exploded schematic diagram of the shaking device in one embodiment of this application.

[0032] Figure 14 (C) is an overall schematic diagram of the shaking device in one embodiment of this application, showing the housing in the first position; Figure 14 (C1) is Figure 14 (C) Schematic diagram of the cross section along the A-A1 direction.

[0033] Figure 15 (D) is a schematic diagram of the overall shaking device in one embodiment of this application, showing the housing in the second position; Figure 15 (D1) is Figure 15 (D) Schematic diagram of the cross section along the B-B1 direction. Detailed Implementation

[0034] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. This application will now be described in detail with reference to the accompanying drawings and embodiments.

[0035] Please see Figure 1-3 As shown, this application provides a foaming test device 100, which includes pipelines, a first valve 130, a second valve 140, a third valve 150, a fourth valve 151, a first syringe 160, and a second syringe 170.

[0036] The tubing includes a first sub-tubing 123 and a second sub-tubing 124. The first sub-tubing 123 has a first end 121 and a second end 122. The second sub-tubing 124 has a third end 125 and a fourth end 126. The second end 122 is connected to an external indwelling needle, and the third end 125 is connected to the first sub-tubing 123.

[0037] Furthermore, one of the first end 121 and the fourth end 126 is connected to a first container 101, which is used to contain powdered contrast agent; the other of the first end 121 and the fourth end 126 is connected to a second container 110, which is used to contain saline solution. The first syringe 160 and the second syringe 170 are used to perform injection and extraction actions, respectively.

[0038] The first valve 130 is provided on the first sub-pipeline 123 and has at least three interfaces, two of which are used to connect to the first sub-pipeline 123 and at least one other interface is used to connect to the outside.

[0039] The second valve 140 is disposed on the first sub-pipeline 123, and the second valve 140 has at least three ports, two of which are used to connect to the first sub-pipeline 123, and at least one other port is used to connect to the first syringe 160.

[0040] The third valve 150 is disposed on the first sub-tube 123 and has at least three ports, two of which are used to connect to the first sub-tube 123 and at least one other port is used to connect to the second syringe 170.

[0041] The fourth valve 151 is disposed on the first sub-pipeline 123 and has at least three interfaces, two of which are used to connect to the first sub-pipeline 123 and at least one other interface is used to connect to the third end 125, so that the first sub-pipeline 123 and the second sub-pipeline 124 are interconnected through the fourth valve 151.

[0042] Furthermore, the foaming test device 100 has a left atrial angiography mode and a right atrial angiography mode. Therefore, the foaming test device 100 can simultaneously perform left and right atrial angiography tests. Specifically, the left atrial angiography mode is used to dissolve powdered contrast agent in physiological saline to form a left atrial angiography foaming solution, and to further process the left atrial angiography mixture to form a right atrial angiography foaming solution. The right atrial angiography mode is used to mix physiological saline, purified air, and the patient's blood to form a right atrial angiography mixture, and to further process the right atrial angiography mixture to form a right atrial angiography foaming solution.

[0043] In the left atrial angiography working mode, one of the first syringe 160 and the second syringe 170 transfers the saline in the second container 110 to the first container 101, so that the contrast agent dissolves in the saline in the first container 101 to form a left atrial angiography mixture, and the first syringe 160 and the second syringe 170 reciprocate to inject the left atrial angiography mixture to form a left atrial angiography bubble fluid.

[0044] In the right atrial angiography working mode, one of the first syringe 160 and the second syringe 170 first draws physiological saline from the second container 110, then draws air from the outside through the first valve 130, and draws blood through the indwelling needle to form a right atrial angiography mixture. The first syringe 160 and the second syringe 170 repeatedly push the right atrial angiography mixture to form right atrial angiography bubble fluid.

[0045] Furthermore, whether it is the left atrial contrast fluid or the right atrial contrast fluid, the reciprocating injection by the first syringe 160 and the second syringe 170 can effectively improve the foaming efficiency of the left atrial contrast fluid or the right atrial contrast fluid, thereby shortening the time for forming the bubble fluid and quickly realizing the automatic preparation of the left atrial contrast fluid or the right atrial contrast fluid. At the same time, it can also improve the quality, preparation efficiency and consistency of the bubble fluid, as well as improve the accuracy of auxiliary screening.

[0046] Furthermore, compared to using only one syringe to inject or extract the left or right atrial contrast fluid, this embodiment utilizes the cooperation of the first syringe 160 and the second syringe 170 to repeatedly inject the left or right atrial contrast fluid. This effectively reduces the resistance of the left or right atrial contrast fluid during its reciprocating motion between the first syringe 160 and the second syringe 170, thereby further improving the preparation efficiency of the left or right atrial contrast fluid.

[0047] Furthermore, after the preparation of the bubbling fluid for left atrial angiography is completed, the bubbling fluid will be injected into the patient's body through an indwelling needle via a vein, and a left atrial bubbling test will be performed.

[0048] Preferably, the first syringe 160 and the second syringe 170 work together to inject the mixture at least 20 times, so that the left atrial contrast mixture can form a left atrial contrast foaming solution with good consistency.

[0049] Furthermore, the bubbling fluid for left atrial angiography can be injected into the patient's body via a first syringe 160 through an indwelling needle via a vein, or via a second syringe 170 through an indwelling needle via a vein.

[0050] Preferably, the left atrial angiography bubbling fluid is injected into the patient's body through the patient's vein via the second syringe 170 and an indwelling needle, in order to shorten the journey of the left atrial angiography bubbling fluid before it enters the patient's body.

[0051] Further, please refer to Figure 1-3As shown, in the first embodiment, the first valve 130, the second valve 140, the third valve 150 and the fourth valve 151 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122, and the first end 121 is connected to the second container 110, and the fourth end 126 is connected to the first container 101.

[0052] In the left atrial angiography mode, the foaming test device 100 has multiple switchable tubing states.

[0053] When switching to the first pipeline state, the first valve 130 and the second valve 140 are respectively configured to connect the liquid path between the second container 110 and the first syringe 160, so as to control the first syringe 160 to draw physiological saline from the second container 110. At this time, the first valve 130 closes the interface connected to the outside, and the second valve 140 closes the first sub-pipeline 123 between the first syringe 160 and the third valve 150.

[0054] Alternatively, the first valve 130, the second valve 140, and the third valve 150 are respectively configured to connect the fluid passage between the second container 110 and the second syringe 170, so as to control the second syringe 170 to draw saline from the second container 110. In this case, the first valve 130 closes the interface connected to the outside, the second valve 140 closes the interface connected to the first syringe 160, and the third valve 150 closes the first sub-tube 123 between the second syringe 170 and the fourth valve 151.

[0055] When switching to the second tubing state, the second valve 140, the third valve 150, and the fourth valve 151 are respectively configured to connect the fluid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to push the drawn saline into the first container 101, so that the contrast agent contained in the first container 101 mixes with the injected saline to obtain the left atrial contrast mixture. At this time, the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the first valve 130, and the fourth valve 151 closes the first sub-tubing 123 between the first container 101 and the second end 122.

[0056] Alternatively, the third valve 150 and the fourth valve 151 are respectively configured to connect the fluid passage between the second syringe 170 and the first container 101, so as to control the second syringe 170 to inject the drawn saline into the first container 101, so that the contrast agent contained in the first container 101 mixes with the injected saline to obtain a left atrial contrast mixture. At this time, the third valve 150 closes the first sub-line 123 between the second syringe 170 and the second valve 140, and the fourth valve 151 closes the first sub-line 123 between the first container 101 and the second end 122.

[0057] When switching to the third tubing state, the second valve 140, the third valve 150, and the fourth valve 151 are respectively configured to connect the fluid passage between the first syringe 160 and the first container 101, so as to control the first syringe 160 to draw left atrial angiography mixture from the first container 101. At this time, the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the first valve 130, the third valve 150 closes the interface connecting to the second syringe 170, and the fourth valve 151 closes the first sub-tubing 123 between the first container 101 and the second end 122.

[0058] Alternatively, the third valve 150 and the fourth valve 151 are respectively configured to connect the fluid passage between the second syringe 170 and the first container 101, so as to control the second syringe 170 to draw left atrial contrast fluid from the first container 101. In this case, the third valve 150 closes the first sub-line 123 between the second syringe 170 and the second valve 140, and the fourth valve 151 closes the first sub-line 123 between the first container 101 and the second end 122.

[0059] When switching to the fourth tubing state, the second valve 140 and the third valve 150 are configured to connect the fluid path between the first syringe 160 and the second syringe 170, thereby controlling the reciprocating injection of the left atrial angiography mixture by the first syringe 160 and the second syringe 170. At this time, the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-tubing 123 between the second syringe 170 and the fourth valve 151.

[0060] Further, please refer to Figure 1 , 2 As shown in Figure 4, in the second embodiment, the first valve 130, the second valve 140, the third valve 150, and the fourth valve 151 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122. However, the difference from the first embodiment is that the first end 121 is connected to the first container 101, and the fourth end 126 is connected to the second container 110.

[0061] In the corresponding left atrial angiography working mode of this embodiment, the foaming test device 100 also has multiple switchable pipeline states.

[0062] When switching to the first tubing state, the second valve 140, the third valve 150, and the fourth valve 151 are respectively configured to connect the fluid path between the second container 110 and the first syringe 160, so as to control the first syringe 160 to draw saline from the second container 110. At this time, the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the first valve 130, the third valve 150 closes the interface connecting the second syringe 170, and the fourth valve 151 closes the first sub-tubing 123 between the second container 110 and the second end 122.

[0063] Alternatively, the third valve 150 and the fourth valve 151 are respectively configured to connect the fluid passage between the second container 110 and the second syringe 170, so as to control the second syringe 170 to draw saline from the second container 110. In this case, the third valve 150 closes the first sub-tube 123 between the second syringe 170 and the second valve 140, and the fourth valve 151 closes the first sub-tube 123 between the second syringe 170 and the second end 122.

[0064] When switching to the second tubing state, the first valve 130 and the second valve 140 are respectively configured to connect the fluid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to push the drawn saline into the first container 101, so that the contrast agent contained in the first container 101 mixes with the injected saline to obtain the left atrial contrast mixture. At this time, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the third valve 150.

[0065] Alternatively, the first valve 130, the second valve 140, and the third valve 150 are respectively configured to connect the fluid passage between the second syringe 170 and the first container 101, so as to control the second syringe 170 to inject the drawn saline into the first container 101, so that the contrast agent contained in the first container 101 mixes with the injected saline to obtain the left atrial contrast mixture. At this time, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-line 123 between the second syringe 170 and the fourth valve 151.

[0066] When switching to the third tubing state, the first valve 130 and the second valve 140 are respectively configured to connect the fluid passage between the first syringe 160 and the first container 101, so as to control the first syringe 160 to draw the left atrial angiography mixture from the first container 101. At this time, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the third valve 150.

[0067] Alternatively, the first valve 130, the second valve 140, and the third valve 150 are respectively configured to connect the fluid passage between the second syringe 170 and the first container 101, so as to control the second syringe 170 to draw left atrial contrast fluid from the first container 101. In this case, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-line 123 between the second syringe 170 and the fourth valve 151.

[0068] When switching to the fourth tubing state, the second valve 140 and the third valve 150 are configured to connect the fluid path between the first syringe 160 and the second syringe 170, thereby controlling the reciprocating injection of the left atrial angiography mixture by the first syringe 160 and the second syringe 170. At this time, the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-tubing 123 between the second syringe 170 and the fourth valve 151.

[0069] Further, please refer to Figure 1 , 2 As shown in Figure 5, in the third embodiment, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122, and the first end 121 is connected to the second container 110, and the fourth end 126 is connected to the first container 101.

[0070] In the left atrial angiography mode, the foaming test device 100 has multiple switchable tubing states.

[0071] When switching to the fifth tubing state, the fourth valve 151, the first valve 130, and the second valve 140 are respectively configured to connect the fluid passage between the second container 110 and the first syringe 160, so as to control the first syringe 160 to draw saline from the second container 110. At this time, the fourth valve 151 closes the interface connecting to the second sub-tubing 124, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the third valve 150.

[0072] Alternatively, the fourth valve 151, the first valve 130, the second valve 140, and the third valve 150 are respectively configured to connect the fluid passage between the second container 110 and the second syringe 170, so as to control the second syringe 170 to draw saline from the second container 110. In this case, the fourth valve 151 closes the interface connecting to the second sub-tube 124, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-tube 123 connecting the second syringe 170 to the second end 122.

[0073] When switching to the sixth tubing state, the fourth valve 151, the first valve 130, and the second valve 140 are respectively configured to connect the fluid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to push the drawn saline into the first container 101, so that the contrast agent contained in the first container 101 mixes with the injected saline to obtain the left atrial contrast mixture. At this time, the fourth valve 151 closes the interface connecting to the second container 110, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the third valve 150.

[0074] Alternatively, the fourth valve 151, the first valve 130, the second valve 140, and the third valve 150 are respectively configured to connect the fluid path between the second syringe 170 and the first container 101, so as to control the second syringe 170 to push the drawn saline solution into the first container 101, so that the contrast agent contained in the first container 101 mixes with the injected saline solution to obtain the left atrial contrast mixture. At this time, the fourth valve 151 closes the interface connecting to the second container 110, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-tube 123 connecting the second syringe 170 to the second end 122.

[0075] When switching to the seventh tubing state, the fourth valve 151, the first valve 130, and the second valve 140 are respectively configured to connect the fluid passage between the first syringe 160 and the first container 101, so as to control the first syringe 160 to draw left atrial angiography mixture from the first container 101. At this time, the fourth valve 151 closes the interface connecting to the second container 110, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the third valve 150.

[0076] Alternatively, the fourth valve 151, the first valve 130, the second valve 140, and the third valve 150 are respectively configured to connect the fluid passage between the second syringe 170 and the first container 101, so as to control the second syringe 170 to draw left atrial contrast fluid from the first container 101. In this case, the fourth valve 151 closes the interface connecting to the second container 110, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-tube 123 connecting the second syringe 170 to the second end 122.

[0077] When switching to the eighth tubing state, the second valve 140 and the third valve 150 are configured to connect the fluid path between the first syringe 160 and the second syringe 170, thereby controlling the reciprocating injection of the left atrial angiography mixture by the first syringe 160 and the second syringe 170. At this time, the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-tubing 123 between the second syringe 170 and the second end 122.

[0078] Further, please refer to Figure 1 , 2 As shown in Figure 6, in the fourth embodiment, the fourth valve 151, the first valve 130, the second valve 140, and the third valve 150 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122. However, the difference from the third embodiment is that the first end 121 is connected to the first container 101, and the fourth end 126 is connected to the second container 110.

[0079] In the corresponding left atrial angiography working mode of this embodiment, the foaming test device 100 also has multiple switchable pipeline states.

[0080] When switching to the fifth tubing state, the fourth valve 151, the first valve 130, and the second valve 140 are respectively configured to connect the fluid passage between the second container 110 and the first syringe 160, so as to control the first syringe 160 to draw saline from the second container 110. At this time, the fourth valve 151 closes the interface connecting to the first container 101, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the third valve 150.

[0081] Alternatively, the fourth valve 151, the first valve 130, the second valve 140, and the third valve 150 are respectively configured to connect the fluid passage between the second container 110 and the second syringe 170, so as to control the second syringe 170 to draw saline from the second container 110. In this case, the fourth valve 151 closes the interface connecting to the first container 101, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-tube 123 connecting the second syringe 170 to the second end 122.

[0082] When switching to the sixth tubing state, the fourth valve 151, the first valve 130, and the second valve 140 are respectively configured to connect the fluid path between the first syringe 160 and the first container 101, so as to control the first syringe 160 to push the drawn saline into the first container 101, so that the contrast agent contained in the first container 101 mixes with the injected saline to obtain the left atrial contrast mixture. At this time, the fourth valve 151 closes the interface connecting to the second container 110, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the third valve 150.

[0083] Alternatively, the fourth valve 151, the first valve 130, the second valve 140, and the third valve 150 are respectively configured to connect the fluid path between the second syringe 170 and the first container 101, so as to control the second syringe 170 to push the drawn saline solution into the first container 101, so that the contrast agent contained in the first container 101 mixes with the injected saline solution to obtain the left atrial contrast mixture. At this time, the fourth valve 151 closes the interface connecting to the second container 110, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-tube 123 connecting the second syringe 170 to the second end 122.

[0084] When switching to the seventh tubing state, the fourth valve 151, the first valve 130, and the second valve 140 are respectively configured to connect the fluid passage between the first syringe 160 and the first container 101, so as to control the first syringe 160 to draw left atrial angiography mixture from the first container 101. At this time, the fourth valve 151 closes the interface connecting to the second container 110, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the third valve 150.

[0085] Alternatively, the fourth valve 151, the first valve 130, the second valve 140, and the third valve 150 are respectively configured to connect the fluid passage between the second syringe 170 and the first container 101, so as to control the second syringe 170 to draw left atrial contrast fluid from the first container 101. In this case, the fourth valve 151 closes the interface connecting to the second container 110, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-tube 123 connecting the second syringe 170 to the second end 122.

[0086] When switching to the eighth tubing state, the second valve 140 and the third valve 150 are configured to connect the fluid path between the first syringe 160 and the second syringe 170, thereby controlling the reciprocating injection of the left atrial angiography mixture by the first syringe 160 and the second syringe 170. At this time, the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-tubing 123 between the second syringe 170 and the second end 122.

[0087] In some embodiments, the fourth valve 151 may also be located on the first sub-pipeline 123 and connected between the second valve 140 and the third valve 150, which will not be described in detail here.

[0088] Further, please refer to Figure 1-2 As shown, the foaming test apparatus 100 also includes a hanger 280. The second container 110 is mounted on the hanger 280.

[0089] Further, please refer to Figure 7-8 As shown, the foaming test apparatus 100 also includes a first valve 130 drive 410, a second valve 140 drive 410, and a third valve 150 drive 410. All three drive components are motors. The first valve 130 drive 410 is connected to the first valve 130 and is used to switch the operating state of the first valve 130. The second valve 140 drive 410 is connected to the second valve 140 and is used to switch the operating state of the second valve 140. The third valve 150 drive 410 is connected to the third valve 150 and is used to switch the operating state of the third valve 150. All three drive components are electrically connected to a control system, which controls the operating modes of these three drive components.

[0090] Furthermore, in right atrial angiography mode, the foaming test device 100 has several different implementations. For details, please refer to... Figure 1-3 As shown, in the first embodiment, the first valve 130, the second valve 140, the third valve 150 and the fourth valve 151 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122, and the first end 121 is connected to the second container 110, and the fourth end 126 is connected to the first container 101.

[0091] In the right atrial angiography mode, the foaming test device 100 has multiple switchable tubing modes.

[0092] When switching to the first tubing mode, the first valve 130 and the second valve 140 are configured to connect the fluid path between the second container 110 and the first syringe 160, thereby controlling the first syringe 160 to draw saline solution from the second container 110. At this time, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the interface connecting the first syringe 160 and the third valve 150.

[0093] When switching to the second tubing mode, the first valve 130, the second valve 140, and the third valve 150 are configured to connect the fluid path between the second container 110 and the second syringe 170, thereby controlling the second syringe 170 to draw saline solution from the second container 110. At this time, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-tubing 123 connecting the second syringe 170 and the fourth valve 151.

[0094] When switching to the third pipeline mode, the first valve 130, the second valve 140, and the third valve 150 are configured to connect the external environment to the liquid path between the second syringe 170 and the external environment, thereby controlling the second syringe 170 to draw air from the external environment. At this time, the first valve 130 closes the interface connecting to the second container 110, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 to the fourth valve 151.

[0095] When switching to the fourth tubing mode, the third valve 150 and the fourth valve 151 are configured to connect the fluid path between the second syringe 170 and the external indwelling needle. At this time, the third valve 150 closes the first sub-tubing 123 between the second syringe 170 and the second valve 140, and the fourth valve 151 closes the interface connecting to the second sub-tubing 124. This controls the second syringe 170 to drain saline solution from the indwelling needle, or to draw blood from the body through the indwelling needle to form a right atrial angiography mixture, or to inject saline solution or eczing fluid into the body.

[0096] When switching to the fifth tubing mode, the second valve 140, the third valve 150, and the fourth valve 151 are configured to connect the fluid path between the first syringe 160 and the external indwelling needle. At this time, the second valve 140 closes the first sub-tubular line 123 connecting the first syringe 160 and the first valve 130, the third valve 150 closes the interface connecting the second syringe 170, and the fourth valve 151 closes the interface connecting the second sub-tubular line 124. This controls the first syringe 160 to either drain saline solution from the indwelling needle or inject saline solution into the body.

[0097] When switching to the sixth tubing mode, the second valve 140 and the third valve 150 are configured to connect the fluid path between the first syringe 160 and the second syringe 170, thereby controlling the reciprocating injection of the right atrial angiography mixture by the first syringe 160 and the second syringe 170. At this time, the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-tubing 123 connecting the second syringe 170 and the fourth valve 151.

[0098] Further, please refer to Figure 1 , 2 As shown in Figure 4, in the second embodiment, the first valve 130, the second valve 140, the third valve 150, and the fourth valve 151 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122. The difference from the first embodiment described above is that the first end 121 is connected to the first container 101, and the fourth end 126 is connected to the second container 110.

[0099] In the right atrial angiography mode of this embodiment, the foaming test device 100 has multiple switchable tubing modes.

[0100] When switching to the first tubing mode, the second valve 140, the third valve 150, and the fourth valve 151 are configured to connect the fluid path between the second container 110 and the first syringe 160, thereby controlling the first syringe 160 to draw saline solution from the second container 110. At this time, the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the first valve 130, the third valve 150 closes the interface connecting the second syringe 170, and the fourth valve 151 closes the first sub-tubing 123 connecting the second container 110 and the second end 122.

[0101] When switching to the second tubing mode, the third valve 150 and the fourth valve 151 are configured to connect the fluid path between the second container 110 and the second syringe 170, thereby controlling the second syringe 170 to draw saline solution from the second container 110. At this time, the third valve 150 closes the first sub-tubing 123 connecting the second syringe 170 and the second valve 140, and the fourth valve 151 closes the first sub-tubing 123 connecting the second container 110 and the second end 122.

[0102] When switching to the third pipeline mode, the first valve 130, the second valve 140, and the third valve 150 are configured to connect the external environment to the liquid path between the second syringe 170 and the external environment, thereby controlling the second syringe 170 to draw air from the external environment. At this time, the first valve 130 closes the interface connecting to the first container 101, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 to the fourth valve 151.

[0103] When switching to the fourth tubing mode, the third valve 150 and the fourth valve 151 are configured to connect the fluid path between the second syringe 170 and the external indwelling needle. At this time, the third valve 150 closes the first sub-tubing 123 between the second syringe 170 and the second valve 140, and the fourth valve 151 closes the interface connecting to the second sub-tubing 124. This controls the second syringe 170 to drain saline solution from the indwelling needle, or to draw blood from the body through the indwelling needle to form a right atrial angiography mixture, or to inject saline solution or eczing fluid into the body.

[0104] When switching to the fifth tubing mode, the second valve 140, the third valve 150, and the fourth valve 151 are configured to connect the fluid path between the first syringe 160 and the external indwelling needle. At this time, the second valve 140 closes the first sub-tubular line 123 connecting the first syringe 160 and the first valve 130, the third valve 150 closes the interface connecting the second syringe 170, and the fourth valve 151 closes the interface connecting the second sub-tubular line 124. This controls the first syringe 160 to either drain saline solution from the indwelling needle or inject saline solution into the body.

[0105] When switching to the sixth tubing mode, the second valve 140 and the third valve 150 are configured to connect the fluid path between the first syringe 160 and the second syringe 170, thereby controlling the reciprocating injection of the right atrial angiography mixture by the first syringe 160 and the second syringe 170. At this time, the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-tubing 123 connecting the second syringe 170 and the fourth valve 151.

[0106] Further, please refer to Figure 1 , 2 As shown in Figure 5, in the third embodiment, the fourth valve 151, the first valve 130, the second valve 140 and the third valve 150 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122, and the first end 121 is connected to the second container 110, and the fourth end 126 is connected to the first container 101.

[0107] In the right atrial angiography mode, the foaming test device 100 has multiple switchable tubing modes;

[0108] When switching to the seventh tubing mode, the fourth valve 151, the first valve 130, and the second valve 140 are configured to connect the fluid path between the second container 110 and the first syringe 160, thereby controlling the first syringe 160 to draw saline solution from the second container 110. At this time, the fourth valve 151 closes the interface connecting to the second sub-tubing 124, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the third valve 150.

[0109] When switching to the eighth tubing mode, the fourth valve 151, the first valve 130, the second valve 140, and the third valve 150 are configured to connect the fluid path between the second container 110 and the second syringe 170, thereby controlling the second syringe 170 to draw saline solution from the second container 110. At this time, the fourth valve 151 closes the interface connecting to the second sub-tubing 124, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-tubing 123 connecting the second syringe 170 and the second end 122.

[0110] When switching to the ninth pipeline mode, the first valve 130, the second valve 140, and the third valve 150 are configured to connect the external environment to the liquid path between the second syringe 170 and the external environment, thereby controlling the second syringe 170 to draw air from the external environment. At this time, the first valve 130 closes the interface connecting to the fourth valve 151, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 and the second end 122.

[0111] When switching to the tenth tubing mode, the third valve 150 is configured to connect the fluid path between the second syringe 170 and the external indwelling needle. This controls the second syringe 170 to discharge saline solution from the indwelling needle, or to draw blood from the body through the indwelling needle to form a right atrial angiography mixture, or to inject saline solution or foaming fluid into the body. At this time, the third valve 150 closes the first sub-tubing 123 connecting the second syringe 170 and the second valve 140.

[0112] When switching to the eleventh tubing mode, the second valve 140 and the third valve 150 are configured to connect the fluid path between the first syringe 160 and the external indwelling needle. This controls the first syringe 160 to discharge saline solution from the indwelling needle or to inject saline solution into the body. At this time, the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the interface connecting to the second syringe 170.

[0113] When switching to the twelfth tubing mode, the second valve 140 and the third valve 150 are configured to connect the fluid path between the first syringe 160 and the second syringe 170, thereby controlling the reciprocating injection of the right atrial angiography mixture by the first syringe 160 and the second syringe 170. At this time, the second valve 140 closes the first sub-tubular 123 connecting the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-tubular 123 connecting the second syringe 170 and the second end 122.

[0114] Further, please refer to Figure 1 , 2 As shown in Figure 6, in the fourth embodiment, the fourth valve 151, the first valve 130, the second valve 140, and the third valve 150 are sequentially arranged on the first sub-pipeline 123 along the direction from the first end 121 to the second end 122. The difference between this embodiment and the third embodiment described above is that the first end 121 is connected to the first container 101, and the fourth end 126 is connected to the second container 110.

[0115] In the right atrial angiography mode of this embodiment, the foaming test device 100 has multiple switchable tubing modes. Specifically, when switched to the seventh tubing mode, the fourth valve 151, the first valve 130, and the second valve 140 are configured to connect the fluid path between the second container 110 and the first syringe 160, so as to control the first syringe 160 to draw physiological saline from the second container 110. At this time, the fourth valve 151 closes the interface connecting to the first container 101, the first valve 130 closes the interface connecting to the outside, and the second valve 140 closes the first sub-tubing 123 connecting the first syringe 160 and the third valve 150.

[0116] When switching to the eighth tubing mode, the fourth valve 151, the first valve 130, the second valve 140, and the third valve 150 are configured to connect the fluid path between the second container 110 and the second syringe 170, thereby controlling the second syringe 170 to draw saline solution from the second container 110. At this time, the fourth valve 151 closes the interface connecting to the first container 101, the first valve 130 closes the interface connecting to the outside, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-tubing 123 connecting the second syringe 170 and the second end 122.

[0117] When switching to the ninth pipeline mode, the first valve 130, the second valve 140, and the third valve 150 are configured to connect the external environment to the liquid path between the second syringe 170 and the external environment, thereby controlling the second syringe 170 to draw air from the external environment. At this time, the first valve 130 closes the interface connecting to the fourth valve 151, the second valve 140 closes the interface connecting to the first syringe 160, and the third valve 150 closes the first sub-pipeline 123 connecting the second syringe 170 and the second end 122.

[0118] When switching to the tenth tubing mode, the third valve 150 is configured to connect the fluid path between the second syringe 170 and the external indwelling needle. This controls the second syringe 170 to discharge saline solution from the indwelling needle, or to draw blood from the body through the indwelling needle to form a right atrial angiography mixture, or to inject saline solution or foaming fluid into the body. At this time, the third valve 150 closes the first sub-tubing 123 connecting the second syringe 170 and the second valve 140.

[0119] When switching to the eleventh tubing mode, the second valve 140 and the third valve 150 are configured to connect the fluid path between the first syringe 160 and the external indwelling needle. This controls the first syringe 160 to discharge saline solution from the indwelling needle or to inject saline solution into the body. At this time, the second valve 140 closes the first sub-tubing 123 between the first syringe 160 and the first valve 130, and the third valve 150 closes the interface connecting to the second syringe 170.

[0120] When switching to the twelfth tubing mode, the second valve 140 and the third valve 150 are configured to connect the fluid path between the first syringe 160 and the second syringe 170, thereby controlling the reciprocating injection of the right atrial angiography mixture by the first syringe 160 and the second syringe 170. At this time, the second valve 140 closes the first sub-tubular 123 connecting the first syringe 160 and the first valve 130, and the third valve 150 closes the first sub-tubular 123 connecting the second syringe 170 and the second end 122.

[0121] In some embodiments, the fourth valve 151 may also be located on the first sub-pipeline 123 and connected between the second valve 140 and the third valve 150, which will not be described in detail here.

[0122] Furthermore, in the foaming test device 100 of the present invention, one of the first end 121 and the fourth end 126 is connected to the first container 101, and the other of the first end 121 and the fourth end 126 is connected to the second container 110. Therefore, the entire foaming test device 100 is automated, and thus the foaming test device 100 realizes the automatic extraction of physiological saline, outside air, blood, left atrial angiography mixture, and right atrial angiography mixture.

[0123] In some embodiments, the second container 110, the first valve 130, the first syringe 160, and the second syringe 170 are sequentially arranged along the first end 121 to the second end 122 of the pipeline. The second syringe 170 is used to inject the obtained foaming liquid (microbubble embolization contrast agent) into the human body. Based on the fact that the foaming test device 100 can automatically draw physiological saline, after the second syringe 170 draws blood, the first syringe 160 can push the drawn physiological saline into the human body to clean the pipeline and prevent blood from clotting in the pipeline and blocking the pipeline.

[0124] In addition, after the foaming fluid in the second syringe 170 is injected into the human body, the second syringe 170 and the first syringe 160 sequentially inject physiological saline into the human body, which can push the microbubble contrast agent into the human body as much as possible and also clean the tube. If the foaming test fails, it will not affect the next foaming test.

[0125] In one embodiment, please refer to Figure 7-11 As shown, the first sub-pipeline is arranged along a straight line. In this invention, by arranging the first sub-pipeline 123 along a straight line and the first syringe 160 and the second syringe 170 side by side, the foaming test device 100 can be miniaturized as much as possible, making it convenient to use.

[0126] Furthermore, the foaming test apparatus 100 of the present invention includes a first syringe driver 180 and a second syringe driver 190. The first syringe driver 180 includes a first syringe driver 180 body and a first syringe driver output end 181 connected together. The first syringe driver output end 181 is connected to the piston of the first syringe 160. The first syringe driver 180 body can drive the first syringe driver output end 181 to move, thereby driving the piston of the first syringe 160 to move.

[0127] The second syringe driver 190 includes a body of the second syringe 170 and a second syringe driver output end 191 connected together. The output end 191 of the second syringe driver is connected to the piston of the second syringe 170. The body of the second syringe driver 190 can drive the output end 191 of the second syringe driver to move, so as to drive the piston of the second syringe 170 to move.

[0128] Specifically, both the first syringe driver 180 and the second syringe driver 190 are lead screw modules. Position sensors are correspondingly provided at the output ends 181 and 191 of both syringe drivers to sense their movement positions and prevent over-extension and safety issues.

[0129] In one embodiment, the foaming test apparatus 100 further includes an air filter 200. The air filter 200 is connected to one of the interfaces of the first valve 130 to purify the air entering from the outside, ensuring that the foaming test is conducted more safely.

[0130] Further, please refer to Figure 7-11 As shown, the foaming test apparatus 100 also includes a first ultrasonic bubble sensor 210. The first ultrasonic bubble sensor 210 is positioned between the second container 110 and the first valve 130 on the pipeline to monitor whether there are bubbles when physiological saline passes through, in order to confirm whether the pipeline is leaking.

[0131] Specifically, when the first syringe 160 and the second syringe 170 draw physiological saline, under normal circumstances, physiological saline is drawn. However, in case of abnormalities, such as poor sealing of the joint and leakage, some air may be drawn. When air passes through the pipe corresponding to the first ultrasonic bubble sensor 210, the first ultrasonic bubble sensor 210 outputs a high level. When the pipe contains physiological saline, it outputs a low level. The control system uses the high and low level signals to determine whether the air passing through is a bubble. When there is a bubble, the system will alarm and stop the next operation, thereby ensuring that the foaming test device 100 can draw physiological saline.

[0132] Please see Figure 7 As shown, the foaming test apparatus 100 also includes a second ultrasonic bubble sensor 220. The second ultrasonic bubble sensor 220 is positioned between the second syringe 170 and the indwelling needle on the pipeline to monitor whether air or large bubbles pass through during the injection of foaming fluid or saline solution, so as to ensure injection safety.

[0133] Specifically, when the foaming fluid is injected into the human body, it flows through the tubing corresponding to the second ultrasonic bubble sensor 220. If air or large bubbles pass by, the second ultrasonic bubble sensor 220 will detect them and output a low-level signal to the control system. The control system will then issue an alarm and take appropriate measures to ensure the safety and reliability of the foaming fluid injected into the human vein. In this invention, the first ultrasonic bubble sensor 210 and the second ultrasonic bubble sensor 220 can also be replaced with other types of sensors such as vision or blood oxygen sensors.

[0134] Please see Figure 8As shown, the foaming test apparatus 100 also includes a blood oxygen detection sensor 230. The blood oxygen detection sensor 230 is positioned between the second syringe 170 and the indwelling needle on the pipeline. It is used to monitor whether blood passes through within a specified time during blood extraction, ensuring the safe conduct of the blood extraction process and preventing negative pressure from forming within the second syringe 170 due to failure to draw blood, which could cause harm to the equipment and the human body. In this invention, the blood oxygen detection sensor 230 can also be replaced with other types of sensors such as infrared sensors or vision sensors.

[0135] Please see Figure 8 As shown, the foaming test apparatus 100 may also include a miniature camera 240. The miniature camera 240 is configured to correspond to the second syringe 170 and is used to capture images of the foaming liquid to confirm the blood content and the number and size of microbubbles in the foaming liquid.

[0136] Specifically, the miniature camera 240 sends the captured images to the control system. On one hand, the control system determines whether the second syringe 170 has drawn a sufficient amount of blood by observing the color and level of the foaming liquid inside the second syringe 170. If no blood is drawn, the liquid inside the second syringe 170 is a mixture of saline and air, and its color is colorless. In other words, the miniature camera 240 is used to confirm whether the second syringe 170 has drawn blood. When no blood is drawn or the amount of blood is insufficient, the number of microbubbles in the foaming liquid will be very small, and they are easily broken, producing large bubbles, which is not conducive to detection.

[0137] On the other hand, the control system calculates the number and size of microbubble plugs in the second syringe 170 shown in the image (it should be noted that a large number of large images need to be fed to the control system for training in the early stage. The control system continuously learns and can eventually feed back the number and size of microbubbles based on the images sent by the miniature camera 240) to provide a reference for the final inspection results. If the number of microbubble plugs is too small, the final inspection results may be inaccurate. If the microbubble plugs are too large, the final inspection results may also be inaccurate.

[0138] Please see Figure 10 As shown, the device 100 also includes a thrust sensor. The thrust sensor includes at least a first thrust sensor 250 and a second thrust sensor 260. The first thrust sensor 250 is disposed corresponding to the output end 181 of the first syringe driver. When mixing the foaming liquid or when the first syringe 160 injects saline solution into the human body, the first thrust sensor 250 is used to sense the magnitude of the injection thrust at the output end 181 of the first syringe driver to ensure injection safety.

[0139] The second thrust sensor 260 is set at the output end 191 of the second syringe driver. When mixing the foaming liquid or when the second syringe 170 injects saline into the human body, the second thrust sensor 260 is used to sense the magnitude of the injection thrust at the output end 191 of the second syringe driver to ensure injection safety.

[0140] Specifically, during injection, the indwelling needle may come into contact with the patient's blood vessel wall, causing the needle insertion point to become blocked or the needle to dislodge. In this case, the injection pressure will rise sharply. If injection continues under these circumstances, it may damage the patient's blood vessel wall or cause bulging of the elbow vein. Therefore, when the force sensor detects that the injection force exceeds a certain range and continues to rise, the system will sound an alarm and stop the injection to avoid harming the patient. The position of the indwelling needle will then need to be manually adjusted.

[0141] Please see Figure 8-9 As shown, the foaming test apparatus 100 of the present invention also includes a dust cover device 270. The dust cover device 270 includes a dust cover and a dust cover drive member 410. The dust cover drive member 410 is connected to the dust cover and is used to drive the dust cover to cover the portion containing components such as the air filter 200, the first syringe 160, the second syringe 170, the first valve 130, the second valve 140, and the third valve 150. Furthermore, the foaming test apparatus 100 has a boss, with a motor for the valve installed at the lower end of the boss, and the first syringe 160, the second syringe 170, the air filter 200, the first valve 130, the second valve 140, the third valve 150, and some pipelines installed above it. This saves space and facilitates the installation and operation of the dust cover, contributing to the miniaturization of the foaming test apparatus 100.

[0142] The foaming test device 100 of the present invention is equipped with a variety of monitoring devices to maximize the safety of the foaming test. Doctors do not need to pay attention to the operation of the equipment at all times and can use it with peace of mind. At the same time, it also reduces the operational burden of doctors. There is no need to manually draw saline, air and blood. The foaming test device 100 operates in a highly automated manner, which is safe and efficient.

[0143] Furthermore, in right atrial angiography mode, the working principle of this foaming test device 100 is as follows:

[0144] Preparation steps: First, the foaming test device 100 is switched to the first tubing mode, and the first syringe 160 draws physiological saline from the container 110; then, the foaming test device 100 is switched to the second tubing mode, and the second syringe 170 draws physiological saline from the container 110; the foaming test device 100 is then switched to the fourth tubing mode, and the second syringe 170 discharges physiological saline from the indwelling needle; finally, the foaming test device 100 is switched to the fifth tubing mode, and the first syringe 160 discharges physiological saline from the indwelling needle; when the first syringe 160 and the second syringe 170 discharge physiological saline from the indwelling needle, both syringes should be pushed all the way down to expel the air from inside the syringes.

[0145] During the preparation step, when the first syringe 160 and the second syringe 170 draw physiological saline, the first ultrasonic bubble sensor 210 monitors whether there are bubbles as the physiological saline passes through. If there are bubbles, an alarm is triggered, and the tubing is checked and repaired.

[0146] Mixture extraction steps: First, the foaming test device 100 switches to the first tubing mode, and the first syringe 160 draws physiological saline from the container 110; Second, the foaming test device 100 switches to the second tubing mode, and the second syringe 170 draws physiological saline from the container 110; Third, the foaming test device 100 switches to the third tubing mode, and the second syringe 170 draws air from the outside; Fourth, the foaming test device 100 switches to the fourth tubing mode, and the second syringe 170 draws blood from the human body through an indwelling needle to obtain the mixture. In this step, the blood oxygen detection sensor 2... Step 30 monitors whether blood passes through within a specified time; if not, an alarm is triggered. Step 5: The foaming test device 100 switches to the fifth pipeline mode, and the first syringe 160 injects physiological saline into the human body. In this step, the second ultrasonic bubble sensor 220 monitors whether large air bubbles or air are present as the foaming liquid passes through. If so, the system alarms, and the equipment is subsequently adjusted to ensure the safety of the foaming liquid injected into the human vein. Simultaneously, the first thrust sensor 250 senses the thrust at the output end 181 of the first syringe drive; if the thrust continues to rise within a certain range, an alarm is triggered, and the indwelling needle is manually adjusted. Additionally, in steps 1 and 2, when the first syringe 160 and the second syringe 170 draw physiological saline, the first ultrasonic bubble sensor 210 monitors whether air bubbles are present as the physiological saline passes through. If air bubbles are present, an alarm is triggered, and the pipeline is checked and repaired.

[0147] Foaming liquid preparation steps: The foaming test device 100 is switched to the sixth pipeline mode. The first syringe 160 and the second syringe 170 reciprocate to inject the mixture. The sum of the number of injections by the first syringe 160 and the second syringe 170 is an even number (the purpose is to ensure that the foaming liquid is injected into the human body through the second syringe 170), and at least 20 times, to obtain the foaming liquid.

[0148] In this step, the miniature camera 240 captures an image of the foaming liquid in the second syringe 170 and sends the image to the control system to confirm whether the blood content in the foaming liquid meets the standard and the number and size of the microbubble plugs, so as to provide a reference for the accuracy of the subsequent foaming test results.

[0149] The first foaming fluid injection procedure is as follows: After obtaining the foaming fluid, the foaming test device 100 switches to the fourth tubing mode, and the second syringe 170 injects the foaming fluid into the human body. During injection, the second thrust sensor 260 senses the magnitude of the injection thrust of the second syringe 170 (more specifically, it senses the magnitude of the thrust at the output end 191 of the second syringe drive). If the injection thrust continues to rise, the system alarms and stops injection. The test is then continued after adjusting the position of the indwelling needle. Furthermore, the second ultrasonic sensor monitors for large air bubbles as the foaming fluid passes through. If large air bubbles are present, the control system alarms, and the foaming test device 100 is inspected before the test is repeated to ensure the safety and reliability of the foaming fluid injected into the human vein.

[0150] First sealing procedure: After the first foaming solution injection, the foaming test device 100 first switches to the second tubing mode, and the second syringe 170 draws physiological saline from the container 110; then the foaming test device 100 switches to the first tubing mode, and the first syringe 160 draws physiological saline from the container 110; the foaming test device 100 then switches to the fourth tubing mode, and the second syringe 170 injects physiological saline into the human body; finally, the foaming test device 100 switches to the fifth tubing mode, and the first syringe 160 injects physiological saline into the human body, thus completing the control group foaming test.

[0151] In this step, when the first syringe 160 and the second syringe 170 draw saline solution, the first ultrasonic bubble sensor 210 monitors whether there are bubbles as the saline solution flows through. If there are bubbles, an alarm is triggered, and the tubing is then checked and repaired. At the same time, when the first syringe 160 and the second syringe 170 inject saline solution into the human body, the first thrust sensor 250 senses the thrust at the output end 181 of the first syringe driver, and the second thrust sensor 260 senses the thrust at the output end 191 of the second syringe driver. If the thrust sensed by either thrust sensor exceeds a certain range and continues to rise, the system will alarm.

[0152] Second foaming fluid injection step: Repeat the above-mentioned mixture extraction step and foaming fluid preparation step to obtain foaming fluid. After obtaining foaming fluid, the patient performs the blowing or Eustachian tube inflation test. When the blowing or Eustachian tube inflation test is successful, the foaming test device 100 switches to the fourth tubing mode, and the second syringe 170 injects the foaming fluid into the human body.

[0153] Second sealing step: Repeat the first sealing step to complete the foaming test of the experimental group.

[0154] Before the first and second sealing steps, there is residual foaming fluid in the first sub-tube 123 between the second syringe 170 and the indwelling needle that has not been injected into the human body. The sealing step can push the residual foaming fluid in the tube into the human body as much as possible, which not only ensures that the foaming fluid is injected in sufficient quantity, but also cleans the tube.

[0155] The foaming test device 100 of this invention eliminates the need for manual extraction of saline, air, and blood, as well as manual injection of foam. Medical personnel simply install the injection consumables onto the foaming test device 100, which then automatically completes the extraction, foaming, injection, and emptying operations, saving labor costs and truly enabling one-person operation to complete the foaming test. (Reference) Figure 12 The foaming test device 100 can also be used with the air blowing device 300. The real-time air pressure value is detected by the pressure sensor inside the air blowing device 300, which replaces the Valsalva action. It is simple to operate and highly accurate.

[0156] On the other hand, please see Figure 1-2 As shown, this application also provides a foaming test system, which includes the foaming test apparatus 100 described above. Therefore, the system possesses all the beneficial effects of the foaming test apparatus 100 described above, which will not be elaborated further here.

[0157] The system also includes a mixing device 400. The mixing device 400 is used to drive the first container 101 to move, so that the contrast agent contained in the first container 101 is fully dissolved in the physiological saline to form a homogeneous left atrial contrast mixture, and to foam the left atrial contrast mixture. Specifically, after the physiological saline is injected into the first container 101 by the first syringe 160 or the second syringe 170, the mixing device 400 drives the first container 101 to move, so that the contrast agent in the first container 101 can quickly and fully dissolve in the physiological saline to form a left atrial contrast mixture, and further shakes the left atrial contrast mixture to ensure that the left atrial contrast mixture is homogeneously mixed and generates a large number of high-quality and stable microbubbles.

[0158] Further, please refer to Figure 1As shown, in one embodiment, the mixing device 400 is integrated on the foaming test device 100, thereby integrating the foaming test device 100 and the mixing device 400 into one unit to facilitate carrying the mixing device 400 and the foaming test device 100.

[0159] Please see Figure 2 As shown, in another embodiment, the mixing device 400 is independent of the foaming test device 100, that is, the mixing device 400 is not integrated into the foaming test device 100, thereby making the system more flexible so that medical personnel can perform right atrial angiography without carrying the mixing device 400, or carry the mixing device 400 and use it in combination with different foaming test devices 100.

[0160] Further, please refer to Figure 12-13 As shown, in one embodiment, the mixing device 400 includes a drive member 410 and a receiving member 420. The receiving member 420 is connected to the output shaft 412 of the drive member 410.

[0161] The receiving member 420 is configured to form a receiving groove 421, which is used to receive the first container 101. Under the drive of the driving member 410, the receiving member 420 drives the first container 101 to reciprocate along the axial direction of the output shaft 412 to achieve mixing of the left atrial contrast fluid, or to reciprocate along the circumferential direction of the output shaft 412 to achieve mixing of the left atrial contrast fluid. Alternatively, it can simultaneously drive the first container 101 to reciprocate along the axial direction of the output shaft 412 and to reciprocate along the circumferential direction of the output shaft 412, thereby making the shaking of the left atrial contrast fluid in the first container 101 more intense, and thus achieving a better mixing effect.

[0162] Furthermore, the mixing device 400 also includes a fixing component 430 and a roller 440. The fixing component 430 is used to mount and fix the drive component 410 so that the drive component 410 is fixed on the foaming test apparatus 100, or at a designated location outside the foaming test apparatus 100.

[0163] A roller 440 is rotatably mounted on one of the fixing component 430 and the receiving member 420, and faces the other of the fixing component 430 and the receiving member 420. The other roller 440 in the fixing component 430 and the receiving member 420 has a groove 422. Under the reciprocating drive of the driving member 410, the roller 440 changes its position on the groove wall of the groove 422, causing the receiving member 420 to reciprocate along the axial direction of the output shaft 412 and to reciprocate along the circumferential direction of the output shaft 412. This allows the first container 101 containing the receiving member 420 to maintain substantially synchronized movement with the receiving member 420.

[0164] Furthermore, the drive unit 410 includes a drive body 411 and an output shaft 412. The drive body 411 is used to drive the output shaft 412 to rotate forward and backward. This causes the receiving member 420 to rotate forward and backward around the output shaft 412 as the rotation center, thereby causing the first container 101 to move synchronously.

[0165] Furthermore, the fixing assembly 430 includes a bracket 431 and a fixing member 432. The drive body 411 is fixedly connected to the bracket 431 and the fixing member 432 by a locking member. The output shaft 412 passes through the bracket 431 and the fixing member 432 in sequence and extends out of the fixing member 432 to connect with the receiving member 420. The bracket 431 is used to fix the mixing device 400.

[0166] Specifically, the bracket 431 includes a connecting plate portion 4311 and mounting plate portions 4312 disposed on opposite sides of the connecting plate portion 4311. The connecting plate portion 4311 and the two mounting plate portions 4312 are configured to form a receiving groove 4313, and the drive body 411 is disposed in the receiving groove 4313. The fixing member 432 is disposed on the side of the connecting plate portion 4311 opposite to the receiving groove 4313, and the locking member passes through the fixing member 432 and the connecting plate portion 4311 in sequence to lock into the drive body 411, so as to fix the drive member 410, the bracket 431 and the fixing member 432 together. The output shaft 412 passes through the connecting plate portion 4311 and the fixing member 432 in sequence and is connected to the receiving member 420.

[0167] The two mounting plates 4312 are used to fix the mixing device 400 on the foaming test device 100, so that the mixing device 400 is integrated on the foaming test device 100; or the two mounting plates 4312 are used to fix the mixing device 400 at a designated position outside the foaming test device 100.

[0168] Furthermore, the two rollers 440 are rotatably disposed on the side of the fixing member 432 facing the receiving member 420 via a rotating shaft 450, and the receiving member 420 is constructed to form a groove 422, which is disposed away from the receiving groove 421.

[0169] Please see Figure 14 As shown in (C), (C1) of 14, (D) of 15 and (D1) of 15, the housing 420 has a first position and a second position relative to the drive member 410 along the axial direction of the output shaft 412, and the housing 420 reciprocates between the first position and the second position under the drive of the drive member 410.

[0170] When the receiving member 420 is in the first position, the two rollers 440 are located at the lowest point of the groove 422, and the receiving member 420 is close to the fixing component 430. When the receiving member 420 is in the second position, the two rollers 440 are located at the highest point of the groove 422, and the receiving member 420 is away from the fixing component 430.

[0171] By setting two rollers 440 to move within the groove 422, the housing 420 can rotate with the output shaft 412 as the rotation center, and can also reciprocate along the circumferential direction of the output shaft 412.

[0172] Furthermore, the drive member 410 drives the housing member 420 to rotate at an angle of less than or equal to 360 degrees in both directions, thereby effectively preventing the second sub-pipe 124 connected to the first container 101 from becoming entangled.

[0173] Preferably, the drive member 410 drives the receiving member 420 to switch rotation directions every 180 degrees along the output shaft 412. That is, after the drive member 410 drives the receiving member 420 to rotate 180 degrees clockwise, it immediately drives the receiving member 420 to rotate 180 degrees counterclockwise, and repeats this process multiple times until the left atrial angiography mixture is fully mixed and a large number of microbubbles are generated.

[0174] Further, please refer to Figure 12 , 13 As shown in (C1) of 14 and (D1) of 15, the mixing device 400 further includes a flexible member 460, which is disposed on the wall of the receiving groove 421 for protecting the first container 101 and / or confining the first container 101 within the receiving groove 421. Preferably, the flexible member 460 is a silicone sleeve, which is attached to the wall of the receiving groove 421 to protect the first container 101 from rigidly colliding with the wall of the receiving groove 421 during movement with the receiving member 420.

[0175] The above are merely preferred embodiments of this application and are not intended to limit this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A foaming test apparatus, characterized in that, include: The tubing includes a first sub-tubing and a second sub-tubing. The first sub-tubing has a first end and a second end opposite to each other. The second sub-tubing has a third end and a fourth end opposite to each other. The second end is connected to an external indwelling needle. The third end is connected to the first sub-tubing. One of the first end and the fourth end is connected to a first container for containing powdered contrast agent. The other of the first end and the fourth end is connected to a second container for containing saline solution. The first and second syringes are used to perform injection and / or extraction actions; A first valve is disposed on the first sub-pipeline and has at least three interfaces, two of which are used to connect to the first sub-pipeline and at least one other interface is used to connect to the outside. The second valve is disposed on the first sub-pipeline and has at least three ports, two of which are used to connect to the first sub-pipeline and at least one other port is used to connect to the first syringe. A third valve is disposed on the first sub-pipeline and has at least three ports, two of which are used to connect to the first sub-pipeline and at least one other port is used to connect to the second syringe. A fourth valve is provided on the first sub-pipeline and has at least three ports, two of which are used to connect to the first sub-pipeline and at least one other port is used to connect to the third end. The foaming test device has a left atrial angiography working mode and a right atrial angiography working mode. In the left atrial angiography working mode, one of the first syringe and the second syringe transfers the saline in the second container to the first container so that the contrast agent dissolves in the saline in the first container to form a left atrial angiography mixture. The first syringe and the second syringe reciprocate to inject the left atrial angiography mixture to form a left atrial angiography bubble solution. In the right atrial angiography working mode, one of the first syringe and the second syringe first draws physiological saline from the second container, then draws air from the outside through the first valve, and draws blood through the indwelling needle to form a right atrial angiography mixture. The first syringe and the second syringe repeatedly inject the right atrial angiography mixture to form a right atrial angiography bubble solution.

2. The foaming test apparatus according to claim 1, characterized in that, The first valve, the second valve, the third valve, and the fourth valve are sequentially arranged on the first sub-pipeline along the direction from the first end to the second end, with the first end connected to the second container and the fourth end connected to the first container; In the left atrial angiography working mode, the foaming test device has multiple switchable tubing states; When switching to the first pipeline state, the first valve and the second valve are respectively set to connect the liquid path between the second container and the first syringe, so as to control the first syringe to draw physiological saline from the second container; Alternatively, the first valve, the second valve, and the third valve are respectively configured to connect the liquid path between the second container and the second syringe, so as to control the second syringe to draw physiological saline from the second container; When switching to the second pipeline state, the second valve, the third valve and the fourth valve are respectively set to connect the liquid path between the first syringe and the first container, so as to control the first syringe to push the drawn physiological saline into the first container, so that the contrast agent contained in the first container is mixed with the injected physiological saline to obtain the left atrial contrast mixture. Alternatively, the third valve and the fourth valve are respectively configured to connect the liquid path between the second syringe and the first container, so as to control the second syringe to push the drawn saline into the first container, so that the contrast agent contained in the first container is mixed with the injected saline to obtain the left atrial contrast mixture. When switching to the third pipeline state, the second valve, the third valve and the fourth valve are respectively set to connect the liquid path between the first syringe and the first container, so as to control the first syringe to draw the left atrial angiography mixture from the first container; Alternatively, the third valve and the fourth valve are respectively configured to connect the liquid path between the second syringe and the first container, so as to control the second syringe to draw the left atrial angiography mixture from the first container; When switched to the fourth pipeline state, the second valve and the third valve are configured to connect the fluid path between the first syringe and the second syringe to control the reciprocating injection of the left atrial angiography mixture by the first syringe and the second syringe.

3. The foaming test apparatus according to claim 1, characterized in that, The fourth valve, the first valve, the second valve, and the third valve are sequentially arranged on the first sub-pipeline along the direction from the first end to the second end, with the first end connected to the second container and the fourth end connected to the first container; In the left atrial angiography working mode, the foaming test device has multiple switchable tubing states; When switching to the fifth pipeline state, the fourth valve, the first valve, and the second valve are respectively configured to connect the liquid path between the second container and the first syringe, so as to control the first syringe to draw physiological saline from the second container; Alternatively, the fourth valve, the first valve, the second valve, and the third valve are respectively configured to connect the liquid path between the second container and the second syringe, so as to control the second syringe to draw physiological saline from the second container; When switched to the sixth tubing state, the fourth valve, the first valve, and the second valve are respectively configured to connect the liquid path between the first syringe and the first container, so as to control the first syringe to push the drawn saline into the first container, so that the contrast agent contained in the first container is mixed with the injected saline to obtain the left atrial contrast mixture. Alternatively, the fourth valve, the first valve, the second valve, and the third valve are respectively configured to connect the liquid path between the second syringe and the first container, so as to control the second syringe to push the drawn saline into the first container, so that the contrast agent contained in the first container is mixed with the injected saline to obtain the left atrial contrast mixture; When switched to the seventh pipeline state, the fourth valve, the first valve, and the second valve are respectively configured to connect the liquid path between the first syringe and the first container, so as to control the first syringe to draw the left atrial angiography mixture from the first container; Alternatively, the fourth valve, the first valve, the second valve, and the third valve are respectively configured to connect the liquid path between the second syringe and the first container, so as to control the second syringe to draw the left atrial angiography mixture from the first container; When switched to the eighth tubing state, the second valve and the third valve are configured to connect the fluid path between the first syringe and the second syringe to control the reciprocating injection of the left atrial angiography mixture by the first syringe and the second syringe.

4. The foaming test apparatus according to claim 1, characterized in that, The first valve, the second valve, the third valve, and the fourth valve are sequentially arranged on the first sub-pipeline along the direction from the first end to the second end, and the first end is connected to the second container; In the right atrial angiography working mode, the foaming test device has multiple switchable tubing modes; When switching to the first tubing mode, the first valve and the second valve are configured to connect the fluid path between the second container and the first syringe, so as to control the first syringe to draw saline from the second container. When switching to the second tubing mode, the first valve, the second valve, and the third valve are configured to connect the fluid path between the second container and the second syringe, so as to control the second syringe to draw saline from the second container; When switching to the third pipeline mode, the first valve, the second valve and the third valve are configured to connect the liquid path between the outside and the second syringe, so as to control the second syringe to draw air from the outside; When switched to the fourth tubing mode, the third valve and the fourth valve are configured to connect the fluid path between the second syringe and the external indwelling needle, so as to control the second syringe to discharge saline from the indwelling needle, or control the second syringe to draw blood from the human body through the indwelling needle to form a right atrial angiography mixture, or control the second syringe to inject saline or foaming fluid into the human body. When switching to the fifth tubing mode, the second valve, the third valve and the fourth valve are configured to connect the first syringe and the external indwelling needle to the fluid path, so as to control the first syringe to discharge saline from the indwelling needle, or to control the first syringe to inject saline into the human body. When switching to the sixth tubing mode, the second valve and the third valve are configured to connect the fluid path between the first syringe and the second syringe to control the reciprocating injection of the right atrial angiography mixture by the first syringe and the second syringe.

5. The foaming test apparatus according to claim 1, characterized in that, The fourth valve, the first valve, the second valve, and the third valve are sequentially arranged on the first sub-pipeline along the direction from the first end to the second end, and the first end is connected to the second container; In the right atrial angiography working mode, the foaming test device has multiple switchable tubing modes; When switching to the seventh tubing mode, the fourth valve, the first valve, and the second valve are configured to connect the fluid path between the second container and the first syringe, so as to control the first syringe to draw saline from the second container; When switching to the eighth tubing mode, the fourth valve, the first valve, the second valve, and the third valve are configured to connect the liquid path between the second container and the second syringe, so as to control the second syringe to draw saline from the second container; When switching to the ninth pipeline mode, the first valve, the second valve, and the third valve are configured to connect the liquid path between the outside and the second syringe, so as to control the second syringe to draw air from the outside. When switched to the tenth tubing mode, the third valve is configured to connect the fluid path between the second syringe and the external indwelling needle, so as to control the second syringe to discharge saline from the indwelling needle, or to control the second syringe to draw blood from the human body through the indwelling needle to form a right atrial angiography mixture, or to control the second syringe to inject saline or foaming fluid into the human body. When switched to the eleventh tubing mode, the second valve and the third valve are configured to connect the fluid path between the first syringe and the external indwelling needle, so as to control the first syringe to discharge saline from the indwelling needle, or to control the first syringe to inject saline into the human body. When switching to the twelfth tubing mode, the second valve and the third valve are configured to connect the fluid path between the first syringe and the second syringe to control the reciprocating injection of the right atrial angiography mixture by the first syringe and the second syringe.

6. The foaming test apparatus according to any one of claims 1-5, characterized in that, The foaming test device also includes a blood oxygen detection sensor, which is positioned on the first sub-tube between the second syringe and the externally connected indwelling needle to monitor whether blood passes through within a specified time during blood collection, ensuring the safe conduct of the blood collection process; and / or The foaming test apparatus further includes an air filter, which is connected to the interface between the first valve and the outside world, for purifying the air entering from the outside; and / or The foaming test apparatus further includes a first ultrasonic bubble sensor, which is positioned on the first sub-pipe between the second container and the first valve to monitor whether bubbles are present as physiological saline passes through, thereby confirming whether the first sub-pipe is leaking; and A second ultrasonic bubble sensor, positioned between the second syringe and the externally connected indwelling needle on the first sub-tube, is used to monitor whether air or large bubbles pass through during the injection of the foaming fluid and saline solution, ensuring injection safety; and / or The foaming testing device further includes a first thrust sensor, which is configured corresponding to the piston of the first syringe. The first thrust sensor is used to sense the injection thrust of the first syringe when the foaming liquid is mixed or when the liquid is injected into the human body, to ensure injection safety. The second thrust sensor, which is configured to correspond to the piston of the second syringe, is used to sense the magnitude of the injection thrust of the second syringe when the foaming liquid is mixed or when the second syringe injects the liquid into the human body, so as to ensure injection safety.

7. A foaming test system, characterized in that, The system includes the foaming test apparatus according to any one of claims 1-6; and A mixing device is used to drive the first container to move so that the contrast agent contained in the first container is fully dissolved in physiological saline to form a homogeneous left atrial contrast mixture, and to foam the left atrial contrast mixture. The mixing device is integrated into the foaming test device or is independent of the foaming test device. The mixing device includes a driving member and a receiving member. The receiving member is connected to the output shaft of the driving member. The receiving member is configured to form a receiving groove for receiving the first container. Under the drive of the driving member, the receiving member drives the first container to reciprocate along the axial direction of the output shaft and / or reciprocate along the circumferential direction of the output shaft.

8. The foaming test system according to claim 7, characterized in that, The mixing device further includes a fixing component for mounting and fixing the driving component; and A roller, rotatably mounted on one of the fixing component and the receiving component, and facing the other of the fixing component and the receiving component; The fixing component and the receiving component are respectively provided with a groove at the other corresponding roller. Under the forward and reverse reciprocating drive of the driving component, the roller changes its position on the groove wall so that the receiving component reciprocates along the axial direction of the output shaft and reciprocates along the circumferential direction of the output shaft.

9. The foaming test system according to claim 8, characterized in that, The driving component includes a driving body and the output shaft; The fixing component includes a bracket and a fixing member. The driving body is fixedly connected to the bracket and the fixing member by a locking member. The output shaft passes through the bracket and the fixing member in sequence and extends out of the fixing member to connect with the receiving member. The bracket is used to fix the mixing device. The two rollers are rotatably disposed on the side of the fixing member facing the receiving member, and the receiving member is configured to form the groove; The receiving member has a first position and a second position relative to the driving member along the axial direction of the output shaft, and the receiving member reciprocates between the first position and the second position under the drive of the driving member; When the receiving member is in the first position, the two rollers are respectively located at the lowest point of the groove, and the receiving member is close to the fixing component; When the receiving member is in the second position, the two rollers are respectively located at the highest point of the groove, and the receiving member is away from the fixing component.

10. The foaming test system according to any one of claims 8-9, characterized in that, The driving component drives the housing to switch the rotation direction every 180 degrees along the output shaft; and / or The mixing device further includes a flexible element disposed on the wall of the receiving groove.

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