Herbicide combination and method for controlling unwanted vegetation

Abstract

The present disclosure relates to a method of controlling unwanted vegetation / weeds. More specifically, the present disclosure relates to a method of controlling weeds of the Amaranthus genus with a synergistic herbicide combination comprising L-glufosinate-ammonium, salts, esters thereof, or combinations thereof, and at least one additional herbicide.

Description

Technical Field

[0001] The present disclosure relates to a method of controlling unwanted vegetation / weeds. More specifically, the present disclosure relates to a method of controlling Amaranthus weeds using a synergistic herbicide combination and compositions of said combination. Background Art

[0002] Weeds are undesirable plants that are harmful to agriculture and severely affect crop yields. Farmers use various types of herbicides to control weeds. Herbicides are chemicals specifically formulated to control unwanted plants / weeds.

[0003] Amaranthus is a widespread genus of annual or short-lived perennial plants, collectively known as Amaranthus plants. Also known as pigweed, this widespread genus of Amaranthus has about 70 species. Amaranthus hybridus is known as smooth pigweed. Amaranthus hybridus is a species in the Amaranthaceae family. It is found in America, Africa, Central and South Asia, and Australia. Amaranthus rugosa is another species in the Amaranthaceae family. It is found in different regions including Africa, Asia, Europe, North America, Oceania, and South America.

[0004] Certain unwanted plant / weed species or unwanted plant / weed populations are not sensitive to certain herbicides. This may be because the herbicides use different biochemical pathways. In situations where one herbicide is ineffective, another herbicide with a different mode of action may achieve better results. Therefore, there is a need to continuously develop effective herbicide combinations to control the growth of unwanted plants / weeds. Currently known herbicides in the art, whether used alone or in combination, are not sufficient to control resistant and persistent Amaranthus weeds, such as Amaranthus oleraceus or Amaranthus rubra.

[0005] Furthermore, selective control of unwanted plants / weeds in crops is a key challenge in modern agriculture. Moreover, herbicides may not always work as expected. Combinations of herbicides may sometimes produce additive or antagonistic effects. It may also be phytotoxic to crops and thus be a bad combination. Therefore, herbicides need to be carefully selected so that they work in combination to exert a synergistic effect, control weeds without being phytotoxic to crops and reduce the chances of weed resistance to a particular herbicide.

[0006] Therefore, there is a need in the art for a method of protecting crops from Amaranthus weeds using a combination of herbicides, which has the advantages of synergy, facilitating resistance management, reducing herbicide usage and improving residual effect. Summary of the invention

[0007] The primary object of the present disclosure is to provide a method for controlling Amaranthus weeds by applying a synergistic herbicide combination.

[0008] Another object of the present disclosure is to provide a method of controlling Amaranthus weeds by applying a synergistic herbicide combination comprising L-glufosinate, its salts, esters, or combinations thereof, and at least one additional herbicide.

[0009] Another object of the present invention is to provide a method for controlling Amaranthus weeds by applying a synergistic herbicide combination, the synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide or a combination thereof.

[0010] It is a further object of the present disclosure to provide a method for controlling Amaranthus weeds by applying a synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or combinations thereof, and at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor, an auxin mimetic herbicide or a combination thereof.

[0011] It is yet another object of the present disclosure to provide a method for controlling Amaranthus weeds by applying a synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least two additional herbicides selected from the group consisting of acetolactate synthase inhibitor herbicides or combinations thereof.

[0012] It is a further object of the present disclosure to provide a method for controlling Amaranthus weeds in plants, wherein the method comprises applying a synergistic herbicide combination comprising L-glufosinate, its salts, esters or combinations thereof and at least one additional herbicide to the plants or the locus where undesirable vegetation occurs or is expected to occur.

[0013] Yet another object of the present disclosure is to provide a method of increasing plant yield by applying a synergistic herbicide combination.

[0014] Another object of the present disclosure is to provide a method for improving plant health by applying a synergistic herbicide combination. DETAILED DESCRIPTION OF THE INVENTION

[0016] In one aspect, a synergistic herbicide combination for controlling Amaranthus weeds is provided, the combination comprising L-glufosinate, its salts, esters or combinations thereof and at least one additional herbicide.

[0017] In another aspect, a synergistic herbicide combination for controlling Amaranthus weeds is provided, the combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide selected from the group consisting of:

[0018] (a) protoporphyrinogen oxidase inhibitor herbicides;

[0019] (b) acetyl coenzyme A (CoA) carboxylase inhibitor herbicides;

[0020] (c) auxin mimetic herbicides;

[0021] (d) acetolactate synthase inhibitor herbicides;

[0022] (e) hydroxyphenylpyruvate dioxygenase inhibitor herbicides;

[0023] or a combination thereof.

[0024] In another aspect, there is provided a synergistic herbicide combination for controlling Amaranthus weeds, the combination comprising:

[0025] (a) L-phosphinothricin, its salts, esters or combinations thereof;

[0026] (b) at least one protoporphyrinogen oxidase inhibitor herbicide; and

[0027] (c) at least one auxin mimetic herbicide.

[0028] In another aspect, there is provided a synergistic herbicide combination for controlling Amaranthus weeds, the combination comprising:

[0029] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0030] (b) at least two acetolactate synthase inhibitor herbicides.

[0031] In another aspect, a synergistic herbicide composition for controlling weeds of the genus Amaranthus is provided, the composition comprising:

[0032] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0033] (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof; and

[0034] (c) at least one agrochemically acceptable ingredient.

[0035] In another aspect, a synergistic herbicide composition for controlling weeds of the genus Amaranthus is provided, the composition comprising:

[0036] (a) L-phosphinothricin, its salts, esters or combinations thereof;

[0037] (b) at least one protoporphyrinogen oxidase inhibitor herbicide;

[0038] (c) at least one auxin mimetic herbicide; and

[0039] (d) at least one agrochemically acceptable excipient.

[0040] In another aspect, there is provided a synergistic herbicide combination for controlling Amaranthus weeds, the combination comprising:

[0041] (a) L-phosphinothricin, its salts, esters or combinations thereof;

[0042] (b) at least two acetolactate synthase inhibitor herbicides; and

[0043] (c) at least one agrochemically acceptable excipient.

[0044] In one aspect, the present disclosure provides a method of controlling Amaranthus weeds, the method comprising applying a synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide to a plant or a locus thereof in need of control.

[0045] In another aspect, a method of controlling Amaranthus weeds is provided, the method comprising applying to a plant or a locus thereof in need of control a synergistic herbicide combination, the synergistic herbicide combination comprising:

[0046] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0047] (b) at least one additional herbicide selected from the group consisting of: at least one protoporphyrinogen oxidase inhibitor herbicide, at least one acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, at least one auxin mimetic herbicide, at least one acetolactate synthase inhibitor herbicide, at least one hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof. DETAILED DESCRIPTION

[0048] The present disclosure will be described below with reference to the attached examples, in which embodiments of the present disclosure are shown. This description is not intended to list in detail all the different ways in which the present disclosure can be used, or all the features that can be added to the present disclosure. For example, the features shown for one embodiment can be incorporated into other embodiments, and the features shown for a specific embodiment can be deleted from the embodiment. Therefore, the present disclosure contemplates that in some embodiments of the present disclosure, any feature or combination of features described herein may be excluded or omitted. In addition, according to the present disclosure, multiple modifications and additions of the various embodiments suggested herein are obvious to those skilled in the art, and this does not depart from the present disclosure. Therefore, the following description is intended to illustrate some specific embodiments of the present disclosure, rather than to describe in detail all its arrangements, combinations and variations.

[0049] For the purpose of the following detailed description, it should be understood that the present disclosure may adopt various alternative variations, unless expressly provided to the contrary. In addition, except in any operating examples or otherwise specified, all numbers representing, for example, the amount of materials / ingredients used in this specification should be understood to be modified by the term "about" in all cases. Taking into account the measurement discussed and the errors associated with the measurement of a particular amount (i.e., the limitations of the measurement system), the "about" or "approximately" used herein includes the stated value and the average value within the acceptable deviation range of the specific value determined by those skilled in the art. For example, "about" can mean within one or more standard deviations, or within ±10% or ±5% of the stated value.

[0050] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those of ordinary skill in the art to which the present disclosure belongs. In the event of a conflict, the present document (including definitions) shall prevail. Although methods and materials similar or equivalent to the methods and materials described herein may be used in the practice or testing of the present disclosure, suitable methods and materials are described herein.

[0051] It is noted that, as used in this specification, the singular forms "a", "an" and "the" include both singular and plural referents, unless the context clearly dictates otherwise.

[0052] Various quantities expressed as "%" or "% w / w" refer to the weight percent of the total solution or composition, unless otherwise specified.

[0053] The terms "comprising," "having," "including," and "containing" should be construed as open-ended terms (ie, meaning "including, but not limited to,") unless otherwise noted.

[0054] Unless otherwise stated, the use of any and all examples or exemplary language (e.g., "such as") is intended merely to better illustrate the present disclosure and does not limit the scope of the present disclosure. No language used in the specification should be construed as indicating any element not recited in the claims as essential to the practice of the present disclosure.

[0055] As used herein, the term "herbicide" refers to a compound that controls or modifies the growth of unwanted weeds.

[0056] The term "herbicidally effective amount" refers to the amount of such compound or combination of such compounds that is capable of controlling or modifying the effect on the growth of harmful plants / unwanted vegetation / weeds. The control effect includes all deviations from natural development, for example: death, growth retardation, leaf burn, albinism, stunting, etc.

[0057] The term "plant" refers to all physical parts of a plant, including seeds, seedlings, saplings, roots, tubers, stems, stalks, leaves and fruits.

[0058] The term "locus" refers to an area where crops are grown or a location where Amaranthus weeds are or are likely to be present or growing, and is intended to include soil, growing media other than soil.

[0059] As used herein, the terms "undesirable vegetation," "undesirable species," "undesirable plants," "noxious plants," "undesirable weeds," "noxious weeds," "unwanted plants," and "weeds" are synonymous.

[0060] The term "gai / L" used herein means the concentration of the corresponding active ingredient in "per liter" of the composition, in "grams". The terms "gai / L" and "gai / L" and "g / L" can be used interchangeably throughout the disclosure.

[0061] The term "g ai / ha" used herein means the concentration of the corresponding active ingredient applied "per hectare" of crop field, and the unit is "gram".

[0062] Unless otherwise specified herein, the description of the range of values ​​is intended only as a shorthand method to refer to each individual value falling within the range individually, and each individual value is incorporated into the specification as if it were individually described herein. The endpoints of all ranges are included in the range and can be independently combined. As used herein, unless otherwise specified in the context, all numerical values ​​or numerical ranges include integers within this range and fractions of values ​​or integers within the range. Thus, for example, the range of 90%-100% includes 91%, 92%, 93%, 94%, 95%, 96%, 97%, etc., and 91.1%, 91.2%, 91.3%, 91.4%, 91.5%, etc., 92.1%, 92.2%, 92.3%, 92.4%, 92.5%, etc. All methods described herein can be performed in a suitable order, unless otherwise specified herein or clearly contradictory to the context.

[0063] In any aspect or embodiment described below, the phrase "comprising" may be replaced by the phrase "consisting of" or "consisting essentially of" or "consisting substantially of." In these aspects or embodiments, the described combinations or compositions include or comprise the specific components described therein or consist essentially of or consist substantially of these components, excluding other fungicides or pesticides or plant growth promoters, adjuvants or excipients not specifically described therein.

[0064] The term "control" in relation to weeds includes controlling weeds as well as protecting plants, plant parts or plant seeds from attack or invasion by said weeds.

[0065] As used herein, the term "pre-emergence" refers to the point in time before seedlings emerge from the ground. When any herbicide is applied pre-emergence, it prevents the formation of germinating weed seedlings.

[0066] As used herein, the term "post-emergence" refers to the point in time after the seedlings emerge from the ground. When any herbicide is used at the post-emergence stage, it prevents the growth of the germinated weed seedlings.

[0067] Glufosinate (also known as phosphinothricin; DL-homoalanine-4-yl (methyl)phosphonic acid), is a non-proteinogenic α-amino acid, namely 2-aminobutyric acid, with the 4-position substituted by a hydroxy (methyl) phosphinothricin. It is a member of the phosphonic acid class and an α-amino acid of non-protein origin. Its ammonium salt (glufosinate ammonium salt) is widely used as a non-selective herbicide and is the active ingredient of various commercial herbicide formulations. Glufosinate has two optical isomers, namely the L-isomer and the D-isomer, of which the L-isomer is highly efficient and the D-isomer is inactive. In addition, L-glufosinate is more environmentally friendly, thereby reducing the use of pesticides and improving the efficiency of pesticide application. The L isomer of glufosinate is a structural analog of glutamate and is therefore a competitive inhibitor of glutamine synthetase (GS) in bacteria and plants (Bayer et al., 1972, Phosphinothricin and phosphinothricyl-alanyl-alanin, Swiss Journal of Chemistry 55, 224-239; Leason et al., 1982, Inhibition of pea leaf glutamine synthetase by methioninsulfoximine, Phosphinothricin and other glutamate analogs, Phytochemistry (Journal) 21, 855-857). The chemical structures of D-glufosinate and L-glufosinate are shown below.

[0068]

[0069] As used herein, the term "phosphinothricin" refers to any racemic phosphonic acid amino acid molecule. The term also includes salts, such as solvates, hydrates, anhydrous forms, crystalline forms, polymorphs, pseudopolymorphs, amorphous forms or mixtures thereof, and sodium, potassium or ammonium salts. The definition includes salts of glufosinate such as monosodium, disodium, monopotassium, dipotassium, calcium, ammonium, -NH3(CH3) + Salt, -NH2(CH3) 2+ Salt, -NH(CH3) 3+ Salt, -NH(CH3)2(C2H4OH) + Salt and -NH2(CH3)(C2H4OH) + Salt. The agrochemically acceptable salt includes glufosinate ammonium salt, glufosinate sodium salt, glufosinate potassium salt or a combination thereof.

[0070] As used herein, the term "L-phosphinothricin" includes L-isomers, salts and esters of glufosinate. The L-enantiomer of glufosinate works by inhibiting glutamine synthetase, resulting in the accumulation of toxic levels of ammonium ions and indirectly inhibiting photosynthesis. It is also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphono)butyric acid. The term can generally refer to any form of L-phosphinothricin, such as solvates, hydrates, esters, anhydrous forms, polymorphs, pseudopolymorphs, amorphous forms or mixtures thereof, as well as sodium salts, potassium salts or ammonium salts. Included in this definition are salts of L-phosphinothricin, such as monosodium salts, disodium salts, monopotassium salts, dipotassium salts, calcium salts, ammonium salts, -NH3(CH3) + Salt, -NH2(CH3) 2+ Salt, -NH(CH3) 3+ Salt, -NH(CH3) 2 (C2H4OH) + Salt and -NH2(CH3)(C2H4OH) + Salt. The agriculturally chemically acceptable salt includes L-phosphine ammonium salt, L-phosphine sodium salt, L-phosphine potassium salt or a combination thereof. The term may also refer to an isomer (racemic) mixture of L-phosphine ammonium, D-phosphine ammonium and its salt, wherein the content of L-phosphine ammonium in the mixture is 70% or higher, preferably 80% or higher, more preferably 90% or higher. Typically, the ratio of L-phosphine ammonium to D-phosphine ammonium can be in the range of about 90:10 to about 99.9:0.1, preferably in the range of about 95:5 to about 99.9:0.1.

[0071] The term "Amaranth weeds" refers to all species within the genus Amaranth in the family Amaranthaceae, including the following: Amaranthus spinulosa, Amaranthus incisus, Amaranthus whitlock, Amaranthus scaly, Amaranthus calyx, Amaranthus sulphureus ... Amaranth, ...

[0072] Some representative embodiments of the present disclosure are discussed below. In a broad sense, the present disclosure is not limited to the specific details and representative methods. This section describes illustrative examples in conjunction with the provided embodiments and methods.

[0073] Proper use of herbicides can effectively control weeds. The activity of herbicides can be enhanced in various ways to achieve maximum benefits. One way is to use herbicides in different combinations. However, determining the appropriate combination, their agrochemical application rates, and the combination ratio is crucial to achieve effective control, but it is not simple.

[0074] Thus, the present disclosure provides a method for partial or complete control of noxious weeds using a combination of two or more herbicides.

[0075] Thus, the present disclosure provides a method for partially or completely controlling noxious weeds using a combination of herbicides.

[0076] Thus, in one embodiment, the present disclosure provides a herbicide combination.

[0077] In another embodiment, the present disclosure provides a herbicide combination comprising L-glufosinate, its salts, esters or a combination thereof and at least one additional herbicide.

[0078] As used throughout the disclosure, L-phosphinothricin and other herbicides include their salts, esters, ethers, polymorphs (including solvates and hydrates). Salts include salts that retain the biological effectiveness and properties of the active ingredient, which are biologically or otherwise undesirable, and include derivatives of the disclosed compounds, wherein the parent compound is modified by preparing its inorganic and organic, nontoxic acid or base addition salts. The salts can be synthesized from the parent compound by conventional chemical methods.

[0079] The inventors of the present invention have found that Amaranthus weeds can be completely controlled using a herbicide combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide selected from the group consisting of:

[0080] (a) protoporphyrinogen oxidase inhibitor herbicides;

[0081] (b) acetyl coenzyme A (CoA) carboxylase inhibitor herbicides;

[0082] (c) auxin mimetic herbicides;

[0083] (d) acetolactate synthase inhibitor herbicides;

[0084] (e) hydroxyphenylpyruvate dioxygenase inhibitor herbicides;

[0085] or a combination thereof.

[0086] It has been found that in the combination of the present invention, L-phosphinothricin, its salts, esters or their combination and other herbicides provide a synergistic effect in controlling Amaranthus weeds. The synergistic degree of the above combination in controlling Amaranthus weeds is unpredictable and unexpected. In addition, the above characteristics and advantages are needed in actual weed control to protect crops from unwanted competing plants, thereby ensuring and / or increasing the yield of plants in terms of quality and quantity.

[0087] Thus, the present disclosure provides a method for partial or complete control of noxious weeds using a synergistic herbicide combination.

[0088] Thus, the present disclosure provides methods for partial or complete control of Amaranthus weeds using synergistic herbicide combinations.

[0089] Thus, in one embodiment, the present disclosure provides a synergistic herbicide combination.

[0090] In another embodiment, the present disclosure provides a synergistic herbicide combination comprising L-glufosinate, its salts, esters, or a combination thereof, and at least one additional herbicide.

[0091] Therefore, in one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, wherein the combination comprises L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide selected from the group consisting of:

[0092] (a) protoporphyrinogen oxidase inhibitor herbicides;

[0093] (b) acetyl coenzyme A (CoA) carboxylase inhibitor herbicides;

[0094] (c) auxin mimetic herbicides;

[0095] (d) acetolactate synthase inhibitor herbicides;

[0096] (e) hydroxyphenylpyruvate dioxygenase inhibitor herbicides;

[0097] or a combination thereof.

[0098] In one embodiment, the salt of L-glufosinate is selected from the group consisting of L-glufosinate sodium salt, L-glufosinate potassium salt, L-glufosinate ammonium salt or a combination thereof. The salt of L-glufosinate is selected from the group consisting of L-glufosinate monosodium salt, disodium salt, monopotassium salt, dipotassium salt, calcium salt, ammonium salt, NH3(CH3) + Salt, -NH2(CH3) 2+ Salt, -NH(CH3) 3+ Salt, -NH(CH3)2(C2H4OH) +Salt, -NH2(CH3)(C2H 4 OH) + salt or a combination thereof.

[0099] In one embodiment, the salt of L-glufosinate is L-glufosinate ammonium salt.

[0100] In one embodiment, the salt of L-glufosinate is L-glufosinate sodium salt.

[0101] In one embodiment, the salt of L-glufosinate is L-glufosinate potassium salt.

[0102] In another embodiment, the present disclosure provides a herbicide combination comprising L-glufosinate ammonium and at least one additional herbicide.

[0103] In another embodiment, the present disclosure provides a synergistic herbicide combination comprising L-glufosinate ammonium and at least one additional herbicide.

[0104] In another embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, wherein the combination comprises L-glufosinate ammonium and at least one additional herbicide selected from the group consisting of:

[0105] (a) protoporphyrinogen oxidase inhibitor herbicides;

[0106] (b) acetyl coenzyme A (CoA) carboxylase inhibitor herbicides;

[0107] (c) auxin mimetic herbicides;

[0108] (d) acetolactate synthase inhibitor herbicides;

[0109] (e) hydroxyphenylpyruvate dioxygenase inhibitor herbicides;

[0110] or a combination thereof.

[0111] In one embodiment, the protoporphyrinogen oxidase inhibitor herbicide is selected from one or more of the herbicides listed below or salts, esters, isomers and combinations thereof.

[0112] Table 1: Protoporphyrinogen oxidase inhibitor herbicides

[0113]

[0114] In one embodiment, the protoporphyrinogen oxidase inhibitor herbicide is selected from one or more of the herbicides listed below or salts, esters, isomers and combinations thereof.

[0115] Table 2: Auxin mimetic herbicides

[0116]

[0117] In one embodiment, the acetyl-CoA carboxylase inhibitor herbicide is selected from one or more of the herbicides listed below or their salts, esters, isomers and combinations thereof.

[0118] Table 3: Acetyl Coenzyme A (CoA) Carboxylase Inhibitor Herbicides

[0119]

[0120] In one embodiment, the acetolactate synthase inhibitor herbicide is selected from one or more of the herbicides listed below or salts, esters, isomers, and combinations thereof.

[0121] Table 4: Acetolactate synthase inhibitor herbicides

[0122]

[0123]

[0124] In one embodiment, the hydroxyphenylpyruvate dioxygenase herbicide is selected from one or more of the herbicides listed below or salts, esters, isomers, and combinations thereof.

[0125] Table 5: Hydroxyphenylpyruvate dioxygenase herbicides

[0126]

[0127] In one embodiment, the present disclosure provides a synergistic herbicide combination, the synergistic herbicide combination comprising:

[0128] (a) the protoporphyrinogen oxidase inhibitor herbicide is saflufenacil;

[0129] (b) the acetyl-CoA carboxylase inhibitor herbicide is selected from the group consisting of quizalofop-p-ethyl, succinimidyl-butyl or a combination thereof;

[0130] (c) the auxin mimetic herbicide is selected from the group consisting of 2,4-D choline, triclopyr or a combination thereof;

[0131] (d) the acetolactate synthase inhibitor herbicide is selected from the group consisting of imazapyr, imazapyr or a combination thereof; and

[0132] (e) The hydroxyphenylpyruvate dioxygenase inhibitor herbicide is mesotrione.

[0133] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate, its salts, esters or a combination thereof and at least one protoporphyrinogen oxidase inhibitor herbicide.

[0134] In a preferred embodiment, the protoporphyrinogen oxidase inhibitor herbicide is saflufenacil.

[0135] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, comprising L-phosphinothricin, its salts, esters or a combination thereof and saflufenacil.

[0136] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate ammonium and saflufenacil.

[0137] In one embodiment, the combination further comprises at least one auxin mimetic herbicide.

[0138] Therefore, a synergistic herbicide combination for controlling Amaranthus weeds is provided, the synergistic herbicide combination comprising L-glufosinate, its salts, esters or combinations thereof, at least one protoporphyrinogen oxidase inhibitor herbicide and at least one auxin mimetic herbicide.

[0139] In one embodiment, the auxin mimetic herbicide is 2,4-dichlorophenoxyacetic acid.

[0140] In one embodiment, the auxin mimetic herbicide is a quaternary ammonium salt of 2,4-dichlorophenoxyacetic acid, the quaternary ammonium salt being produced by reacting 2,4-dichlorophenoxyacetic acid with choline.

[0141] In a preferred embodiment, the auxin mimetic herbicide is 2,4-D choline.

[0142] In one embodiment, the auxin mimetic herbicide is triclopyr.

[0143] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or a combination thereof, saflufenacil and 2,4-D choline.

[0144] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate ammonium, saflufenacil, and 2,4-D choline.

[0145] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, comprising L-glufosinate ammonium, its salts, esters or a combination thereof, saflufenacil and triclopyr.

[0146] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate ammonium, saflufenacil and triclopyr.

[0147] Therefore, a synergistic herbicide combination for controlling Amaranthus weeds is provided, the synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or a combination thereof and at least one acetyl-CoA (CoA) carboxylase inhibitor herbicide.

[0148] In one embodiment, the acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide is quizalofop-p-ethyl.

[0149] In one embodiment, the acetyl-CoA carboxylase inhibitor herbicide is succinimidyl.

[0150] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or a combination thereof and quizalofop-p-ethyl.

[0151] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate ammonium and quizalofop-p-ethyl.

[0152] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or a combination thereof and succinimidyl.

[0153] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate ammonium and glufosinate-butyl.

[0154] Therefore, a synergistic herbicide combination for controlling Amaranthus weeds is provided, the synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or a combination thereof and at least one acetolactate synthase inhibitor herbicide.

[0155] In one embodiment, the acetolactate synthase inhibitor herbicide is a combination of imazapyr and imazapyr.

[0156] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate ammonium, its salts, esters or a combination thereof, imazapyr and imazapyr.

[0157] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate ammonium, imazapyr and imazapyr.

[0158] Therefore, a synergistic herbicide combination for controlling Amaranthus weeds is provided, the synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or a combination thereof and at least one hydroxyphenylpyruvate dioxygenase inhibitor herbicide.

[0159] In one embodiment, the hydroxyphenylpyruvate dioxygenase inhibitor herbicide is mesotrione.

[0160] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or a combination thereof and mesotrione.

[0161] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate ammonium and mesotrione.

[0162] In one embodiment, the present disclosure provides a herbicide combination comprising:

[0163] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0164] (b) at least one additional herbicide selected from the group consisting of protoporphyrinogen oxidase inhibitor herbicides or combinations thereof;

[0165] or

[0166] (b) at least two additional herbicides selected from the group consisting of acetolactate synthase inhibitor herbicides.

[0167] In one embodiment, the combination further comprises at least one additional herbicide selected from the group consisting of auxin mimetic herbicides or combinations thereof.

[0168] In one embodiment, the present disclosure provides a method of controlling weeds by applying a herbicide combination comprising:

[0169] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0170] (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof; wherein the weeds include Amaranth weeds.

[0171] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate, its salts, esters or a combination thereof and at least one additional herbicide, wherein the weight ratio of L-glufosinate, its salts, esters or a combination thereof to the at least one additional herbicide ranges from about 1:100 to about 100:1.

[0172] In one embodiment, the present disclosure provides a synergistic herbicide combination for controlling Amaranthus weeds, the synergistic herbicide combination comprising L-glufosinate ammonium and at least one additional herbicide, wherein the weight ratio of L-glufosinate ammonium and the at least one additional herbicide ranges from about 1:100 to about 100:1.

[0173] In one embodiment, the weight ratio of L-glufosinate, its salts, esters, or combinations thereof to the at least one protoporphyrinogen oxidase inhibitor herbicide ranges from about 1:100 to about 100:1.

[0174] In one embodiment, the weight ratio of L-glufosinate, its salts, esters, or combinations thereof to the at least one acetyl-CoA carboxylase inhibitor herbicide ranges from about 1:100 to about 100:1.

[0175] In one embodiment, the weight ratio of L-glufosinate, its salts, esters, or combinations thereof to the at least one auxin mimetic herbicide ranges from about 1:100 to about 100:1.

[0176] In one embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof to the at least one acetolactate synthase inhibitor herbicide ranges from about 1:100 to about 100:1.

[0177] In one embodiment, the weight ratio of L-phosphinothricin, its salts, esters or combinations thereof to the at least one hydroxyphenylpyruvate dioxygenase inhibitor herbicide ranges from about 1:100 to about 100:1.

[0178] In a preferred embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof to at least one additional herbicide is selected from the group consisting of 1:1, 1:10, 1:20, 1:30, 1:40, 1:50, 1:60, 1:70, 1:80, 1:90 and 1:100.

[0179] In a preferred embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof to at least one additional herbicide is selected from the group consisting of 1:1, 10:1, 20:1, 30:1, 40:1, 50:1, 60:1, 70:1, 80:1, 90:1 and 100:1.

[0180] In another embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof to the at least one additional herbicide ranges from about 1:75 to about 75:1.

[0181] In yet another embodiment, the weight ratio of L-glufosinate, its salts, esters, or combinations thereof to the at least one additional herbicide ranges from about 1:50 to about 50:1.

[0182] In yet another embodiment, the weight ratio of L-glufosinate, its salts, esters, or combinations thereof to the at least one additional herbicide ranges from about 1:25 to about 25:1.

[0183] In yet another embodiment, the weight ratio of L-glufosinate, its salts, esters, or combinations thereof to the at least one additional herbicide ranges from about 1:10 to about 10:1.

[0184] In a preferred embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof to the at least one additional herbicide ranges from about 1:6 to about 6:1.

[0185] In a preferred embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof to the at least one additional herbicide ranges from about 1:5 to about 5:1.

[0186] In a preferred embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof to the at least one protoporphyrinogen oxidase inhibitor herbicide is about 1:2.5.

[0187] In a preferred embodiment, the weight ratio of L-glufosinate ammonium salt to saflufenacil is about 1:2.5.

[0188] In a preferred embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof to at least one auxin mimetic herbicide is about 1:1.6.

[0189] In a preferred embodiment, the weight ratio of L-glufosinate ammonium salt to triclopyrazone is about 1:1.6.

[0190] In a preferred embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof to at least one auxin mimetic herbicide is about 1:1.7.

[0191] In a preferred embodiment, the weight ratio of L-glufosinate ammonium to 2,4-D choline is about 1:1.7.

[0192] In a preferred embodiment, the weight ratio of L-phosphinothricin, its salts, esters or combinations thereof to at least one acetyl-CoA carboxylase inhibitor herbicide is about 5.6:1.

[0193] In a preferred embodiment, the weight ratio of L-glufosinate ammonium to quizalofop-ethyl is about 5.6:1.

[0194] In a preferred embodiment, the weight ratio of L-phosphinothricin, its salts, esters or combinations thereof to at least one acetyl-CoA carboxylase inhibitor herbicide is about 2.33:1.

[0195] In a preferred embodiment, the weight ratio of L-glufosinate ammonium salt to glufosinate-butyl is about 2.33:1.

[0196] In a preferred embodiment, the weight ratio of L-phosphinothricin, its salts, esters or combinations thereof to the at least one hydroxyphenylpyruvate dioxygenase inhibitor herbicide is about 1:1.7.

[0197] In a preferred embodiment, the weight ratio of L-glufosinate ammonium salt to mesotrione is about 1:1.7.

[0198] In a preferred embodiment, the weight ratio of L-phosphinothricin, its salts, esters or combinations thereof to the at least one acetolactate synthase inhibitor herbicide is about 1:1.8.

[0199] In a preferred embodiment, the weight ratio of L-glufosinate ammonium salt to imazapic acid is 1:1.8.

[0200] In a preferred embodiment, the weight ratio of L-phosphinothricin, its salts, esters or combinations thereof to the at least one acetolactate synthase inhibitor herbicide is about 1.6:1.

[0201] In a preferred embodiment, the weight ratio of L-glufosinate ammonium salt to imazapic acid is 1:1.6.

[0202] In one embodiment, at least one additional herbicide that can be combined with L-phosphinothricin, its salts, esters, or combinations thereof is selected from the group consisting of:

[0203] (a) protoporphyrinogen oxidase inhibitor herbicides;

[0204] (b) acetyl coenzyme A (CoA) carboxylase inhibitor herbicides;

[0205] (c) auxin mimetic herbicides;

[0206] (d) acetolactate synthase inhibitor herbicides;

[0207] (e) hydroxyphenylpyruvate dioxygenase inhibitor herbicides;

[0208] or a combination thereof.

[0209] In one embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof, at least one protoporphyrinogen oxidase inhibitor herbicide and at least one auxin mimetic herbicide ranges from about 1:100:100 to about 100:1:1.

[0210] In a preferred embodiment, the weight ratio of L-glufosinate, its salts, esters or combinations thereof, at least one protoporphyrinogen oxidase inhibitor herbicide and at least one auxin mimetic herbicide is selected from the group consisting of 1:100:100, 10:90:90, 20:80:80, 30:70:70, 40:60:60, 50:50:50, 60:40:40, 70:30:30, 80:20:20, 90:10:10 and 100:1:1.

[0211] In one embodiment, the weight ratio of L-glufosinate ammonium, the at least one protoporphyrinogen oxidase inhibitor herbicide, and the at least one auxin mimetic herbicide is about 1:2.5:1.62.

[0212] In a preferred embodiment, the weight ratio of L-glufosinate ammonium salt, saflufenacil and triclopyrazone is about 1:2.5:1.62.

[0213] In one embodiment, the weight ratio of L-glufosinate ammonium, the at least one protoporphyrinogen oxidase inhibitor herbicide, and the at least one auxin mimetic herbicide is about 1:2.5:1.7.

[0214] In a preferred embodiment, the weight ratio of L-glufosinate ammonium, saflufenacil and 2,4-D choline is about 1:2.5:1.7.

[0215] In one embodiment, the weight ratio of L-phosphinothricin, its salts, esters or combinations thereof to the at least two acetolactate synthase inhibitor herbicides is about 1:1.8:0.6.

[0216] In a preferred embodiment, the weight ratio of L-glufosinate ammonium salt, imazapyr and imazapyr is about 1:1.8:0.6.

[0217] In one aspect, the present disclosure provides a method of controlling Amaranthus weeds at a locus, the method comprising applying a synergistic herbicide combination comprising L-phosphinothricin, its salts, esters, or combinations thereof, and at least one additional herbicide selected from the group consisting of:

[0218] (a) protoporphyrinogen oxidase inhibitor herbicides;

[0219] (b) acetyl coenzyme A (CoA) carboxylase inhibitor herbicides;

[0220] (c) auxin mimetic herbicides;

[0221] (d) acetolactate synthase inhibitor herbicides;

[0222] (e) hydroxyphenylpyruvate dioxygenase inhibitor herbicides;

[0223] or a combination thereof.

[0224] In one embodiment, the method comprises applying the present herbicide combination to a locus of vegetation where Amaranthus weeds are present or expected to be present.

[0225] In one embodiment, the method of controlling Amaranthus weeds comprises applying to the locus thereof a synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide, wherein the L-phosphinothricin, its salts, esters or combinations thereof are applied at an application rate of about 50 g ai / hectare to about 350 g ai / hectare.

[0226] In one embodiment, the method of controlling Amaranthus weeds comprises applying to the locus thereof a synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide, wherein the L-phosphinothricin, its salts, esters or combinations thereof are applied at an application rate of about 100 g ai / hectare to about 250 g ai / hectare.

[0227] In a preferred embodiment, the L-glufosinate ammonium salt used in the present combination is applied at an application rate of about 150 grams of active ingredient per hectare.

[0228] In another embodiment, the present disclosure provides a method of controlling Amaranthus weeds at a locus thereof, the method comprising applying a synergistic herbicide combination comprising at least one additional herbicide selected from the group consisting of:

[0229] (a) the protoporphyrinogen oxidase inhibitor herbicide is applied at a rate of from about 5 g active ingredient / hectare to about 200 g active ingredient / hectare;

[0230] (b) the acetyl coenzyme A (CoA) carboxylase inhibitor herbicide is applied at a rate of about 5 grams of active ingredient per hectare to about 200 grams of active ingredient per hectare;

[0231] (c) the auxin mimetic herbicide is applied at a rate of about 50 g ai / hectare to about 600 g ai / hectare;

[0232] (d) the acetolactate synthase inhibitor herbicide is applied at a rate of from about 5 grams of active ingredient per hectare to about 100 grams of active ingredient per hectare; and

[0233] (e) The hydroxyphenylpyruvate dioxygenase inhibitor herbicide is applied at a rate of about 10 g ai / hectare to about 400 g ai / hectare.

[0234] In another embodiment, the present disclosure provides a method of controlling Amaranthus weeds, the method comprising applying to the locus thereof a synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide selected from a protoporphyrinogen oxidase inhibitor herbicide, wherein the protoporphyrinogen oxidase inhibitor herbicide is applied at an application rate of about 5 grams of active ingredient / hectare to about 200 grams of active ingredient / hectare.

[0235] In one embodiment, the protoporphyrinogen oxidase inhibitor herbicide used in the present combination is applied at a rate of about 10 grams of active ingredient per hectare to about 100 grams of active ingredient per hectare.

[0236] In one embodiment, the protoporphyrinogen oxidase inhibitor herbicide used in the present combination is applied at a rate of about 15 grams of active ingredient per hectare to about 45 grams of active ingredient per hectare.

[0237] In a preferred embodiment, the application rate of saflufenacil used in the present combination is about 30 g active ingredient / hectare.

[0238] In another embodiment, the present disclosure provides a method of controlling Amaranthus weeds, the method comprising applying to a locus thereof a synergistic herbicide combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide selected from an acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide, wherein the acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide is applied at an application rate of about 5 g ai / hectare to about 200 g ai / hectare.

[0239] In one embodiment, the amount of acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide used in the present combination is an application rate of about 5 grams of active ingredient per hectare to about 100 grams of active ingredient per hectare.

[0240] In one embodiment, the amount of acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide used in the present combination is an application rate of about 5 grams of active ingredient per hectare to about 50 grams of active ingredient per hectare.

[0241] In a preferred embodiment, the application rate of quizalofop-ethyl used in the present combination is about 25 g ai / hectare.

[0242] In a preferred embodiment, the application rate of saccharoline used in the present combination is about 25 grams of active ingredient per hectare.

[0243] In another embodiment, the present disclosure provides a method of controlling Amaranthus weeds, the method comprising applying to a locus thereof a synergistic herbicide combination comprising L-phosphinothricin or a salt thereof and an additional herbicide selected from at least one auxin mimetic herbicide, wherein the auxin mimetic herbicide is applied at an application rate of about 50 g ai / hectare to about 600 g ai / hectare.

[0244] In one embodiment, the amount of auxin mimetic herbicide used in the present combination is an application rate of about 100 grams of active ingredient per hectare to about 400 grams of active ingredient per hectare.

[0245] In one embodiment, the amount of auxin mimetic herbicide used in the present combination is an application rate of about 150 grams of active ingredient per hectare to about 350 grams of active ingredient per hectare.

[0246] In a preferred embodiment, the application rate of triclopyr used in the present combination is about 228 grams of active ingredient per hectare.

[0247] In a preferred embodiment, the 2,4-D choline used in the present combination is applied at a rate of about 228 g ai / hectare.

[0248] In another embodiment, the present disclosure provides a method of controlling Amaranthus weeds, the method comprising applying to the locus thereof a synergistic herbicide combination comprising L-phosphinothricin or a salt thereof and an additional herbicide selected from at least one acetolactate synthase inhibitor herbicide, wherein the acetolactate synthase inhibitor herbicide is applied at an application rate of about 5 grams of active ingredient / hectare to about 100 grams of active ingredient / hectare.

[0249] In one embodiment, the amount of acetolactate synthase inhibitor herbicide used in the present combination is an application rate of about 5 grams of active ingredient per hectare to about 80 grams of active ingredient per hectare.

[0250] In one embodiment, the amount of acetolactate synthase inhibitor herbicide used in the present combination is an application rate of about 5 grams of active ingredient per hectare to about 60 grams of active ingredient per hectare.

[0251] In one embodiment, the amount of acetolactate synthase inhibitor herbicide used in the present combination is an application rate of about 5 grams of active ingredient per hectare to about 20 grams of active ingredient per hectare.

[0252] In one embodiment, the amount of acetolactate synthase inhibitor herbicide used in the present combination is an application rate of about 10.5 grams of active ingredient per hectare, wherein the acetolactate synthase inhibitor herbicide is imazapyr.

[0253] In one embodiment, the amount of acetolactate synthase inhibitor herbicide used in the present combination is an application rate of about 20 grams of active ingredient per hectare to about 40 grams of active ingredient per hectare.

[0254] In one embodiment, the amount of acetolactate synthase inhibitor herbicide used in the present combination is about 31.5 grams of active ingredient per hectare at an application rate, wherein the acetolactate synthase inhibitor herbicide is imazapic.

[0255] In another embodiment, the present disclosure provides a method of controlling Amaranthus weeds, the method comprising applying to the locus thereof a synergistic herbicide combination comprising L-phosphinothricin or a salt thereof and an additional herbicide selected from at least one protoporphyrinogen oxidase inhibitor herbicide, wherein the protoporphyrinogen oxidase inhibitor herbicide is applied at an application rate of about 10 grams of active ingredient / hectare to about 400 grams of active ingredient / hectare.

[0256] In one embodiment, the amount of protoporphyrinogen oxidase inhibitor herbicide used in the present combination is an application rate of about 25 grams of active ingredient per hectare to about 250 grams of active ingredient per hectare.

[0257] In one embodiment, the amount of protoporphyrinogen oxidase inhibitor herbicide used in the present combination is an application rate of about 50 grams of active ingredient per hectare to about 150 grams of active ingredient per hectare.

[0258] In a preferred embodiment, the application rate of mesotrione used in the present combination is about 100 grams of active ingredient per hectare.

[0259] In another aspect, there is provided the use of a synergistic herbicide combination for controlling weeds in the genus Amaranthus.

[0260] In another aspect, there is provided a use of a synergistic herbicide combination comprising L-glufosinate, its salts, esters or combinations thereof and at least one additional herbicide for controlling Amaranthus weeds.

[0261] In another aspect, there is provided the use of a synergistic herbicide combination comprising L-glufosinate ammonium and at least one additional herbicide for controlling weeds of the genus Amaranth.

[0262] In another aspect, there is provided a use of a synergistic herbicide combination for controlling weeds of the genus Amaranthus, wherein the synergistic herbicide combination comprises:

[0263] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0264] (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof.

[0265] In another aspect, there is provided a use of a synergistic herbicide combination for controlling weeds of the genus Amaranthus, wherein the synergistic herbicide combination comprises:

[0266] (a) L-glufosinate ammonium; and

[0267] (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof.

[0268] In one embodiment, the herbicide combination of the present disclosure can be used in agricultural land, such as fields, rice fields, lawns, orchards; or non-agricultural land. The present disclosure can be used to control diseases in agricultural land to cultivate plants without causing any phytotoxicity to the plants.

[0269] In one embodiment, the compositions and methods disclosed herein can be used to control unwanted vegetation in a variety of crop and non-crop applications. In some embodiments, the compositions and methods disclosed herein can be used to control unwanted vegetation in a variety of crops.

[0270] Examples of crops for which the composition of the present invention can be used include, but are not limited to, corn, rice, wheat, barley, rye, oats, sorghum, cotton, soybeans, peanuts, buckwheat, sugar beets, rapeseed, sunflowers, sugar cane, tobacco, etc.; vegetables: Solanaceae vegetables, such as eggplant, tomato, bell pepper, pepper, potato, etc.; Cucurbitaceae vegetables, such as cucumber, pumpkin, zucchini, watermelon, cantaloupe, pumpkin, etc.; Cruciferae vegetables, such as radish, white radish, horseradish, Brussels sprouts, Chinese cabbage, cabbage, mustard, broccoli, cauliflower, etc.; Asteraceae vegetables, such as burdock, wormwood, artichoke, lettuce, etc.; Liliaceae vegetables, such as shallot, onion, garlic and asparagus, etc.; Umbelliferae vegetables, such as carrot, parsley, celery, parsnip, etc.; Chenopodiaceae vegetables, such as spinach, Swiss chard, etc.; Mintaceae vegetables, such as perilla, mint, basil, etc.; Strawberry , sweet potato, Japanese yam, taro, etc., flowers, foliage plants, lawn grass; fruits: pome fruits such as apples, pears, citrus, etc.; hard-fleshed fruits such as peaches, plums, nectarines, plums, cherries, apricots, prunes, etc.; citrus fruits such as oranges, lemons, limes, grapefruits, etc.; nuts such as chestnuts, walnuts, hazelnuts, almonds, pistachios, cashews, macadamia nuts, etc.; berries such as blueberries, cranberries, blackberries, raspberries, etc.; grapes, persimmons, olives, plums, bananas, coffee, dates, coconuts, etc.; trees other than fruit trees; tea trees, mulberry trees, flowering plants; trees such as ash trees, birch trees, dogwood trees, eucalyptus trees, ginkgo trees, lilac trees, maples, oak trees, poplar trees, southern European bauhinia trees, sweet gum trees, sycamore trees, beech trees, Japanese cypress trees, fir trees, hemlock trees, junipers, pine trees, spruce trees and yew trees or combinations thereof.

[0271] In another embodiment, the present disclosure provides a herbicide composition for controlling Amaranthus weeds, the composition comprising:

[0272] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0273] (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof.

[0274] In one embodiment, the present disclosure provides a herbicide composition for controlling Amaranthus weeds, the composition comprising:

[0275] (a) L-glufosinate ammonium; and

[0276] (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof.

[0277] In one embodiment, the amount of L-glufosinate, its salts, esters, or combinations thereof present in the herbicidal composition is in the range of about 100 g ai / L to 400 g ai / L.

[0278] In one embodiment, the amount of L-glufosinate, its salts, esters, or combinations thereof present in the herbicidal composition is in the range of about 180 g ai / L to 380 g ai / L.

[0279] In one embodiment, the amount of L-glufosinate, its salts, esters, or combinations thereof present in the herbicidal composition is in the range of about 250 g ai / L to 350 g ai / L.

[0280] In a preferred embodiment, the amount of L-glufosinate ammonium present in the herbicide composition is about 280 g active ingredient per liter.

[0281] In one embodiment, the present disclosure provides a herbicide combination comprising at least one additional herbicide selected from the group consisting of:

[0282] (a) the protoporphyrinogen oxidase inhibitor herbicide ranges from about 300 grams of active ingredient per liter to about 1200 grams of active ingredient per liter;

[0283] (b) the acetyl coenzyme A (CoA) carboxylase inhibitor herbicide ranges from about 5 grams of active ingredient per liter to about 200 grams of active ingredient per liter;

[0284] (c) the auxin mimetic herbicide ranges from about 100 grams of active ingredient per liter to about 1000 grams of active ingredient per liter;

[0285] (d) the acetolactate synthase inhibitor herbicide ranges from about 100 grams active ingredient per liter to about 1100 grams active ingredient per liter; and

[0286] (e) The hydroxyphenylpyruvate dioxygenase inhibitor herbicide ranges from about 250 grams of active ingredient per liter to about 750 grams of active ingredient per liter.

[0287] In another embodiment, the present disclosure provides a method of controlling Amaranthus weeds, the method comprising applying to a locus a synergistic combination comprising L-phosphinothricin, its salts, esters, or combinations thereof and at least one additional herbicide selected from a protoporphyrinogen oxidase inhibitor herbicide, wherein the protoporphyrinogen oxidase inhibitor herbicide is present in an amount ranging from about 300 grams of active ingredient per liter to about 1200 grams of active ingredient per liter.

[0288] In one embodiment, the amount of protoporphyrinogen oxidase inhibitor herbicide used in the present combination is in the range of about 400 grams active ingredient per liter to about 1000 grams active ingredient per liter.

[0289] In one embodiment, the amount of protoporphyrinogen oxidase inhibitor herbicide used in the present combination is in the range of about 600 grams active ingredient per liter to about 800 grams active ingredient per liter.

[0290] In a preferred embodiment, the amount of saflufenacil used in the present combination is about 700 g active ingredient / L.

[0291] In another embodiment, the present disclosure provides a method of controlling Amaranthus weeds, the method comprising applying to a locus a synergistic combination comprising L-phosphinothricin, its salts, esters, or combinations thereof and at least one additional herbicide selected from an acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide, wherein the acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide is present in an amount ranging from about 10 grams of active ingredient / liter to about 800 grams of active ingredient / liter.

[0292] In one embodiment, the amount of acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide used in the present combination is in the range of about 10 grams active ingredient per liter to about 500 grams active ingredient per liter.

[0293] In one embodiment, the amount of acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide used in the present combination is in the range of about 20 grams active ingredient per liter to about 200 grams active ingredient per liter.

[0294] In one embodiment, the amount of acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide used in the present combination is in the range of about 75 g ai / L to about 150 g ai / L, wherein the acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide is saccharoline.

[0295] In one embodiment, the amount of acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide used in the present combination is about 120 grams of active ingredient per liter, wherein the acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide is saccharoline.

[0296] In one embodiment, the amount of acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide used in the present combination is in the range of about 25 g ai / L to about 75 g ai / L, wherein the acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide is saccharoline.

[0297] In one embodiment, the amount of acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide used in the present combination is about 50 grams of active ingredient per liter, wherein the acetyl-Coenzyme A (CoA) carboxylase inhibitor herbicide is saccharoline.

[0298] In another embodiment, the present disclosure provides a method of controlling green amaranth, the method comprising applying a synergistic combination comprising L-glufosinate, its salts, esters, or combinations thereof and at least one additional herbicide selected from an auxin herbicide, wherein the auxin herbicide is present in an amount ranging from about 100 grams of active ingredient per liter to about 1000 grams of active ingredient per liter.

[0299] In one embodiment, the amount of auxinic herbicide used in the present combination ranges from about 200 grams a.i. / liter to about 700 grams a.i. / liter.

[0300] In one embodiment, the amount of auxinic herbicide used in the present combination ranges from about 300 grams a.i. / liter to about 600 grams a.i. / liter.

[0301] In a preferred embodiment, the amount of triclopyr used in the present combination is about 456 g active ingredient / L.

[0302] In a preferred embodiment, the amount of 2,4-D choline used in the present combination is about 480 grams of active ingredient per liter.

[0303] In another embodiment, the present disclosure provides a method of controlling green amaranth, the method comprising applying a synergistic combination comprising L-phosphinothricin, its salts, esters, or combinations thereof and at least one additional herbicide selected from a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, wherein the hydroxyphenylpyruvate dioxygenase inhibitor herbicide is present in an amount ranging from about 200 grams of active ingredient per liter to about 750 grams of active ingredient per liter.

[0304] In one embodiment, the amount of hydroxyphenylpyruvatedioxygenase inhibitor herbicide used in the present combination is in the range of about 300 grams active ingredient per liter to about 650 grams active ingredient per liter.

[0305] In one embodiment, the amount of hydroxyphenylpyruvatedioxygenase inhibitor herbicide used in the present combination is in the range of about 400 grams active ingredient per liter to about 550 grams active ingredient per liter.

[0306] In a preferred embodiment, the amount of mesotrione used in the present combination is about 480 g a.i. / L.

[0307] In another embodiment, the present disclosure provides a method of controlling green amaranth, the method comprising applying a synergistic combination comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide selected from an acetolactate synthase inhibitor herbicide, wherein the acetolactate synthase inhibitor herbicide is present in an amount ranging from about 100 grams of active ingredient / liter to about 1100 grams of active ingredient / liter.

[0308] In another embodiment, the present disclosure provides a method of controlling green amaranth, the method comprising applying a synergistic combination comprising L-phosphinothricin, its salts, esters, or combinations thereof and at least one additional herbicide selected from an acetolactate synthase inhibitor herbicide, wherein the acetolactate synthase inhibitor herbicide is present in an amount ranging from about 300 grams of active ingredient / liter to about 1100 grams of active ingredient / liter.

[0309] In one embodiment, the amount of acetolactate synthase inhibitor herbicide used in the present combination is in the range of about 500 grams active ingredient per liter to about 900 grams active ingredient per liter.

[0310] In one embodiment, the amount of acetolactate synthase inhibitor herbicide used in the present combination is in the range of about 600 grams active ingredient per liter to about 800 grams active ingredient per liter.

[0311] In a preferred embodiment, the amount of imazapiclone used in the present combination is about 525 g active ingredient / L.

[0312] In a preferred embodiment, the amount of imazapyr used in the present combination is about 175 g active ingredient / L.

[0313] In one embodiment, the present invention provides a combination of L-glufosinate, its salts, esters, or combinations thereof and at least one additional herbicide, wherein the combination provides about 50% to about 100% weed control.

[0314] In one embodiment, the present invention provides the use of L-glufosinate, its salts, esters or combinations thereof applied at 150 grams of active ingredient per hectare in combination with at least one additional herbicide applied in the range of about 5 grams of active ingredient per hectare to about 300 grams of active ingredient per hectare, wherein the combination provides a weed control rate of about 50% to about 100%.

[0315] In one embodiment, the present invention provides a combination of L-phosphinothricin, its salts, esters or combinations thereof applied at 150 g ai / hectare and saflufenacil applied at 30 g ai / hectare for controlling green amaranth, wherein the combination provides about 90% weed control within 3 days or days after application (DAA).

[0316] In one embodiment, the present invention provides a use of L-glufosinate, its salts, esters or combinations thereof applied at 150 g ai / hectare, in combination with saflufenacil applied at 30 g ai / hectare and triclopyr applied at 228 g ai / hectare for controlling green amaranth, wherein the combination provides about 100% weed control within 3 days or days after application (DAA).

[0317] In one embodiment, the present invention provides a combination of L-glufosinate, its salts, esters or combinations thereof applied at 150 g ai / hectare, saflufenacil applied at 30 g ai / hectare and 2,4-D choline applied at 228 g ai / hectare for controlling green amaranth, wherein the combination provides about 100% weed control within 3 days or days after application (DAA).

[0318] In one embodiment, the present invention provides a combination of L-glufosinate, its salts, esters or combinations thereof applied at 150 g ai / hectare and quizalofop-p-ethyl applied at 25 g ai / hectare for controlling green amaranth, wherein the combination provides about 51% weed control within 3 days or days after application (DAA).

[0319] In one embodiment, the present invention provides a combination of L-glufosinate, its salts, esters or combinations thereof applied at 150 g ai / hectare and saccharoline ester applied at 25 g ai / hectare for controlling green amaranth, wherein the combination provides about 65% weed control within 14 days or 14 days after application (DAA).

[0320] In one embodiment, the present invention provides a combination of L-glufosinate, its salts, esters or combinations thereof applied at 150 g ai / hectare and mesotrione applied at 100 g ai / hectare for controlling wrinkled amaranth, wherein the combination provides about 70% weed control within 3 days or within 3 days after application (DAA) and about 95% weed control within 7 days or within 7 days after application (DAA).

[0321] In one embodiment, the present invention provides a use of L-glufosinate, its salts, esters or combinations thereof applied at 150 g ai / hectare, and imazapyr applied at 31.5 g ai / hectare and imazapyr applied at 10.5 g ai / hectare for controlling Amaranthus fulvidrafa, wherein the combination provides about 70% weed control within 3 days or days after application (DAA).

[0322] In one embodiment, the herbicide composition for controlling Amaranthus weeds according to the present disclosure further comprises at least one agrochemically acceptable excipient / additive in addition to L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide.

[0323] In another embodiment, the present disclosure provides a herbicide composition for controlling Amaranthus weeds, the composition comprising:

[0324] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0325] (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof; and

[0326] (c) at least one agrochemically acceptable excipient.

[0327] In another embodiment, the present disclosure provides a herbicide composition for controlling Amaranthus weeds, the composition comprising:

[0328] (a) L-glufosinate ammonium; and

[0329] (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof; and

[0330] (c) at least one agrochemically acceptable excipient.

[0331] In a preferred embodiment, the Amaranth weed is Amaranthus viridis.

[0332] In a preferred embodiment, the Amaranth weed is Amaranthus rugosa.

[0333] In one embodiment, the present combination / composition may further comprise one or more insecticides, fungicides, auxiliary herbicides, or combinations thereof.

[0334] In one embodiment, examples of auxiliary herbicides that can be combined with the present herbicide combination include tetrafluanid, pyridazifop, pyrimidinesulfuron, quinclorac, bispyribac, cypermethrin, benpyrazone, triazole, fluazifop, flubendiamide, flubutamide, dichloroisothiazide, SL-1201, cyproconazole, dimethoate, fluazifop, benpyrazone, pyrimidinesulfuron, pinoxadone, oxadiazine, pyrimidinesulfuron, cypermethrin, fluazifop, cypermethrin, Thiophanate, flupysulfuron, clomiphenecarb, pyrasulfuron, bensulfuron, foramsulfuron, pyrasulfoacil, bifenazolin, indazine flupyamide, fenquinoxaline, clofopyralid, flusulfuron-butyl, cyproconazole, sodium salt of oxaflutole, diclofenac, trifluoperazine, cyclazine, methoxyfenoxam, chlorpyrifos, pyrasulfuron-butyl, triazole, bensulfuron, flupyralid, flupyridine-butyl, pyrasulfoacil, or a combination thereof.

[0335] In one embodiment, the agrochemically acceptable excipient / carrier / additive comprises at least one solvent, surfactant, colorant, dispersant, emulsifier, thickener, antifreeze agent, biocide, defoamer, stabilizer, wetting agent or a combination thereof.

[0336] In one embodiment, the surfactant may be selected from a nonionic surfactant, an anionic surfactant, a cationic surfactant, or a combination thereof.

[0337] In one embodiment, examples of nonionic surfactants include polyarylphenol polyethoxy ethers, polyalkylphenol polyethoxy ethers, polyethylene glycol ether derivatives of saturated fatty acids, polyethylene glycol ether derivatives of unsaturated fatty acids, polyethylene glycol ether derivatives of aliphatic alcohols, polyethylene glycol ether derivatives of cyclic aliphatic alcohols, fatty acid esters of polyoxyethylene sorbitan, alkoxylated vegetable oils, alkoxylated acetylenic glycols, polyalkoxylated alkylphenols, fatty acid alkoxylates, sorbitol alkoxylates, sorbitol esters, C8-C22 Alkyl or alkenyl glycosides, polyalkoxy styryl aryl ethers, alkyl amine oxides, block copolymer ethers, polyalkoxylated fatty glycerides, polyalkylene glycol ethers, linear aliphatic or aromatic polyesters, organosiloxanes, polyaryl phenols, sorbitan ester alkoxylates, polyalkylene oxide block copolymers, acrylic acid copolymers and monoesters and diesters of ethylene glycol, or combinations thereof.

[0338] In one embodiment, examples of anionic surfactants include alcohol sulfates, alcohol ether sulfates, alkyl aryl ether sulfates, alkyl aryl sulfonates (such as alkyl benzene sulfonates and alkyl naphthalene sulfonates) and their salts, alkyl sulfonates, monophosphates or diphosphates of polyalkoxylated alkyl alcohols or alkyl phenols, C 12 -C 15 Alkyl alcohol or polyalkoxylated C 12 -C 15 Mono- or di-sulfosuccinates of alkanols, alcohol ether carboxylates, phenol ether carboxylates, polyacid esters of ethoxylated polyoxyalkylene glycols composed of oxybutylene or tetrahydrofuran residues, sulfoalkylamides and their salts (such as sodium salt of N-methyl-N-oleyl taurate), polyoxyalkylene alkylphenol carboxylates, polyoxyalkylene alcohol carboxylates alkyl polyglycoside / alkenyl succinic anhydride condensation products, alkyl ester sulfates, naphthalene sulfonates, naphthalene formaldehyde condensates, alkyl sulfonamides, sulfonated aliphatic polyesters, sulfates of styrylphenyl alkoxylates, sulfonates of styrylphenyl alkoxylates and their corresponding sodium, potassium, calcium, magnesium, zinc, ammonium, alkylammonium, diethanolammonium or triethanolammonium salts, salts of lignin sulfonic acid such as sodium, potassium, magnesium, calcium or ammonium salts, polyarylphenol polyalkoxy ether sulfates and polyarylphenol polyalkoxy ether phosphates, and sulfated alkylphenol ethoxylates, phosphated alkylphenol ethoxylates, or combinations thereof.

[0339] In one embodiment, the cationic surfactant comprises C8-C 18 Alkanolamides of fatty acids and C8-C 18 Fatty amine polyalkoxylate, C 10 -C 18 Alkyl dimethyl benzyl ammonium chloride, coconut alkyl dimethyl aminoacetic acid, C8-C 18 Phosphate esters of fatty amine polyalkoxylates or combinations thereof.

[0340] In one embodiment, those skilled in the art can easily determine the emulsifier that is advantageously used herein, and this emulsifier comprises various nonionic, anionic, cationic and amphoteric emulsifiers, or a mixture of two or more emulsifiers.For example, the example of the nonionic emulsifier that can be used to prepare emulsifiable concentrates comprises polyalkylene glycol ethers and alkyl and aryl phenols, fatty alcohols, fatty amines or fatty acids and ethylene oxide, propylene oxide (such as ethoxylated alkylphenol) and the condensation product of the carboxylic acid ester dissolved with polyol or polyoxyalkylene.Cationic emulsifiers comprise quaternary ammonium compounds and fatty amine salts.Anionic emulsifiers comprise the oil-soluble salts (such as calcium) of alkylaryl sulfonic acid, the oil-soluble salts of sulfated polyglycol ethers and the salt of suitable phosphorylated polyglycol ethers or their combination.

[0341] In one embodiment, the colorant may be selected from: iron oxide, titanium oxide and Prussian blue, and organic dyes such as alizarin dyes, azo dyes or metal phthalocyanine dyes, and trace elements such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc or combinations thereof.

[0342] Another embodiment involves adding a thickener or binder, which can be selected from the group consisting of molasses, sugar, alginate, karaya gum, guar gum, tragacanth gum, polysaccharide gum, mucilage, xanthan gum, or a combination thereof. In another embodiment, the binder can be selected from the group consisting of silicates such as magnesium aluminum silicate, polyvinyl acetate, polyvinyl acetate copolymers, polyvinyl alcohol, polyvinyl alcohol copolymers, cellulose (including ethyl cellulose and methyl cellulose, hydroxymethyl cellulose, hydroxypropyl cellulose, hydroxymethyl propyl cellulose), polyvinyl pyrrolidone, dextrin, maltodextrin, polysaccharides, fats, oils, proteins, gum arabic, shellac, vinylidene chloride, vinylidene chloride copolymers, calcium lignin sulfonate, acrylic acid copolymers, starch, polyvinyl acrylate, zein, gelatin, carboxymethyl cellulose, Cellulose, chitosan, polyethylene oxide, acrylimide polymers and copolymers, polyhydroxyethyl acrylate, methylacrylimide monomer, alginate, ethyl cellulose, polychloroprene and syrup or mixtures thereof; polymers and copolymers of vinyl acetate, methyl cellulose, vinylidene chloride, acrylic acid, cellulose, polyvinyl pyrrolidone and polysaccharides; polymers and copolymers of vinylidene chloride and vinyl acetate-ethylene copolymers; combinations of polyvinyl alcohol and sucrose; plasticizers such as glycerol, propylene glycol, polyglycol or combinations thereof.

[0343] In another embodiment, the antifreeze agent added to the composition can be an alcohol selected from the group consisting of ethylene glycol, 1,2-propylene glycol, 1,3-propylene glycol, 1,2-butylene glycol, 1,3-butylene glycol, 1,4-butylene glycol, 1,4-pentanediol, 3-methyl-1,5-pentanediol, 2,3-dimethyl-2,3-butanediol, trimethylolpropane, mannitol, sorbitol, glycerol, pentaerythritol, 1,4-cyclohexanedimethanol, xylenol, bisphenols such as bisphenol A, etc. In addition, ether alcohols such as diethylene glycol, triethylene glycol, tetraethylene glycol, polyoxyethylene or polyoxypropylene glycol, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, triethylene glycol monomethyl ether, butoxyethanol, butanediol monobutyl ether, dipentaerythritol, tripentaerythritol, tetrapentaerythritol, diglycerol, triglycerol, tetraglycerol, pentaglycerol, hexaglycerol, heptaglycerol, octaglycerol or combinations thereof having a molecular weight of up to about 4000.

[0344] According to one embodiment, the biocide comprises benzothiazole, 1,2-benzisothiazolin-3-one, sodium dichloro-s-triazinetrione, sodium benzoate, potassium sorbate, 1,2-phenyl-isothiazolin-3-one, inter chloroxylenol paraoxybenzoatebutyl, or a combination thereof.

[0345] According to one embodiment, the defoaming agent comprises polydimethoxysiloxane, polydimethylsiloxane, alkyl polyacrylate, castor oil, fatty acids, fatty acid esters, fatty acid sulfates, fatty alcohols, fatty alcohol esters, fatty alcohol sulfates, olive oil, mono- and diglycerides, paraffin oil, paraffin, polypropylene glycol, silicone oil, vegetable and animal fats, sulfates of vegetable and animal fats, vegetable and animal oils, sulfates of vegetable and animal oils, vegetable and animal waxes, sulfates of vegetable and animal waxes, agents based on silicon or magnesium stearate, or combinations thereof.

[0346] According to one embodiment, representative organic liquids that can be used to prepare emulsifiable concentrates include, for example, aromatic liquids such as xylene, propylbenzene fractions or mixed naphthalene fractions, mineral oils, substituted aromatic organic liquids such as dioctyl phthalate, kerosene, dialkylamides of various fatty acids, particularly dimethylamides of fatty diols and diol derivatives such as n-butyl ether, ether or methyl ether of diethylene glycol and methyl ether of triethylene glycol. Mixtures of two or more organic liquids are also often suitable for preparing emulsifiable concentrates. The formulation may also contain other compatible additives, such as plant growth regulators and other biologically active compounds used in agriculture.

[0347] According to one embodiment, the additives for the formulation include, for example, a solid carrier such as kaolinite, sericite, diatomaceous earth, slaked lime, calcium carbonate, talc, white carbon, kaolin, bentonite, clay, sodium carbonate, sodium bicarbonate, saltpeter, zeolite or starch; a solvent such as water, toluene, xylene, solvent naphtha, dioxane, dimethyl sulfoxide, N,N-dimethylformamide, dimethylacetamide, N-methyl-2-pyrrolidone or alcohol; an anionic surfactant such as a salt of a fatty acid, a benzoate, a polycarboxylate, a salt of an alkyl sulfate ester, an alkyl sulfate, an alkyl aryl sulfate, an alkyl diglycol ether sulfate, a salt of an alcohol sulfate, an alkyl sulfonate, an alkyl aryl sulfonate, an aryl sulfonate, a lignin sulfonate, an alkyl diphenyl oxide disulfonate, a polystyrene sulfonate, a salt of an alkyl phosphate ester, an alkyl aryl phosphate, a styryl aryl phosphate, a salt of a polyoxyethylene alkyl ether sulfate, a polyoxyethylene alkyl aryl ether sulfate, a polyoxyethylene alkyl salts of alkyl aryl ether sulfates, polyoxyethylene alkyl ether phosphates, polyoxyethylene alkyl aryl phosphates, salts of polyoxyethylene aryl ether phosphates, naphthalenesulfonic acid condensed with formaldehyde, or salts of alkylnaphthalenesulfonic acid condensed with formaldehyde; nonionic surfactants such as sorbitan fatty acid esters, glycerol fatty acid esters, fatty acid polyglycerol esters, fatty acid alcohol polyglycol ethers, acetylene glycol, acetylene alcohol, oxyalkylene block polymers, polyoxyethylene alkyl ethers, polyoxyethylene alkyl aryl ethers, polyoxyethylene Oxyethylene styryl aryl ether, polyoxyethylene glycol alkyl ether, polyethylene glycol, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene glycerol fatty acid ester, polyoxyethylene hydrogenated castor oil or polyoxypropylene fatty acid ester; and vegetable oil or mineral oil, such as olive oil, kapok oil, castor oil, palm oil, camellia oil, coconut oil, sesame oil, corn oil, rice bran oil, peanut oil, cottonseed oil, soybean oil, rapeseed oil, linseed oil, tung oil or liquid paraffin. As long as it meets the purpose of the present disclosure, these additives can be appropriately selected for use alone, or they can be used in combination as a mixture of two or more additives. In addition, additives other than the above can be appropriately selected from those additives known in the art. For example, various commonly used additives such as fillers, thickeners, anti-settling agents, antifreeze agents, dispersion stabilizers, safeners, mildew inhibitors, foaming agents, disintegrants and adhesives can be used.

[0348] According to one embodiment, the agrochemical formulation may also contain one or more antioxidants. Preferably, the agrochemical formulation contains an antioxidant. Antioxidants are, for example, amino acids (e.g., glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles and imidazole derivatives (e.g., urocanic acid), peptides such as, for example, D, L-carnosine, D-carnosine, L-carnosine and their derivatives (e.g., anserine), carotenoids, carotenes (e.g., α-carotene, β-carotene, lycopene) and their derivatives, lipoic acid and its derivatives (e.g., dihydrolipoic acid), gold thioglucose, propylthiouracil and other thio compounds (e.g., thioglycerol, thiosorbitol, thioglycolic acid, thioredoxin, glutathione, cysteine, cystine, cystamine and its glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl, lauryl , palmitoyl, oleyl, γ-linoleyl, cholesteryl and glyceryl esters) and their salts, dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and its derivatives (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts), and very low tolerated doses (e.g., picomoles per kilogram to picomoles per kilogram) of sulfoximine compounds (e.g., buthionine sulfoximine, homocysteine ​​sulfoximine, buthionine sulfone, pentathionine sulfoximine, hexathionine sulfoximine, heptathionine sulfoximine), also metal chelators (e.g., α-hydroxy fatty acids, EDTA, EGTA, phytic acid, lactoferrin), α-hydroxy acids (e.g., citric acid,Lactic acid, malic acid), humic acid, bile acid, bile extract, gallic acid esters (such as propyl gallate, octyl gallate and lauryl gallate), flavonoids, catechins, bilirubin, biliverdin and its derivatives, unsaturated fatty acids and their derivatives (such as gamma-linolenic acid, linoleic acid, arachidonic acid, oleic acid), folic acid and its derivatives, hydroquinone and its derivatives (such as arbutin), ubiquinone and ubiquinol and its derivatives, vitamin C and its derivatives (such as ascorbyl palmitate, ascorbyl stearate, ascorbyl dipalmitate, ascorbyl acetate, magnesium ascorbyl phosphate, sodium ascorbate and magnesium ascorbyl, disodium ascorbyl phosphate and disodium ascorbyl sulfate, potassium ascorbyl tocopheryl phosphate, chitosan ascorbate), isoascorbic acid acid and its derivatives, tocopherol and its derivatives (e.g. tocopheryl acetate, tocopheryl linoleate, tocopheryl oleate and tocopheryl succinate, tocophereth-5, tocophereth-10, tocophereth-12, tocophereth-18, tocophereth-50, tocophersolan), vitamin A and its derivatives (e.g. vitamin A palmitate), coniferyl benzoate of benzoin resin, rutin, rutinic acid and its derivatives, disodium rutinyl sulfate, cinnamic acid and its derivatives (e.g. ferulic acid, ethyl ferulate, caffeic acid), kojic acid, chitosan glycolate and chitosan salicylate, butylated hydroxytoluene, dibutyl hydroxyanisole, nordihydroguaiacic acid, nordihydroguaiacic acid, trihydroxybutyrophenone, uric acid and its derivatives, mannose and its derivatives, selenium and selenium derivatives (e.g. selenomethionine), stilbene and stilbene derivatives (e.g. stilbene oxide, trans-stilbene oxide). According to one embodiment, mixtures of the above antioxidants are possible.

[0349] According to one embodiment, examples of solvents are water, aromatic solvents (e.g., xylene), paraffins (e.g., mineral oil fractions such as kerosene or diesel), coal tar and oils of plant or animal origin, aliphatic, cyclic and aromatic hydrocarbons (e.g., toluene, xylene, paraffins, tetralin, alkylated naphthalenes or their derivatives), alcohols (e.g., methanol, butanol, pentanol, benzyl alcohol, cyclohexanol), ketones (e.g., cyclohexanone, γ-butyrolactone), pyrrolidones (NMP, NEP, NOP), acetates (ethylene glycol diacetate), glycols, fatty acid dimethylamides, fatty acids and fatty acid esters, isophorone and dimethyl sulfoxide or combinations thereof.

[0350] According to one embodiment, solvent mixtures may also be used.

[0351] According to one embodiment, exemplary surfactants include alkali metal salts, alkaline earth metal salts and ammonium salts of lignin sulfonic acid, naphthalene sulfonates, phenol sulfonic acid, dibutylnaphthalene sulfonic acid, alkyl aryl sulfonates, alkyl sulfates, alkyl sulfonates, fatty alcohol sulfates, fatty acids and sulfated fatty alcohol glycol ethers, in addition to condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensates of naphthalene or naphthalene sulfonic acid with phenol and formaldehyde, polyoxyethylene octylphenol ethers, ethoxylated isooctylphenol, octylphenol, nonylphenol, alkylphenol polyglycol ethers, tributylphenyl polyglycol ethers, tristearylphenyl polyglycol ethers, alkylaryl polyether alcohols, alcohol and fatty alcohol / ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylenes, lauryl alcohol polyglycol ether acetals, sorbitol esters, lignin sulfite waste liquor and methylcellulose or combinations thereof.

[0352] According to one embodiment, examples of carriers include mineral soils such as silica gel, silicates, talc, kaolin, magnesia clay, attapulgite, limestone, lime, chalk, red basalt, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea, and products of plant origin such as grain flour, bark flour, wood flour and nut shell flour, cellulose powder, polyvinyl pyrrolidone and other solid carriers or combinations thereof.

[0353] According to one embodiment, exemplary preservatives include 1,2-benzisothiazolin-3-one and / or 2-methyl-2H-isothiazol-3-one or sodium benzoate or benzoic acid or a combination thereof.

[0354] In another aspect, the present compositions may further comprise at least one safener.

[0355] In one embodiment, the safener can be selected from the group consisting of: isoxadiazole ethyl, clofosbumid, pyraclostrobin, naphthalene dicarboxylic anhydride, oxadiazole, benzenesulfonamide, N-(aminocarbonyl)-2-chlorobenzenesulfonamide (2-CBSU), cypermethrin, dichloroacetamide, bicyclopyrone, oxadiazole ethyl, chlorpyrifos, fluazifop, dichloroacetamide safeners (e.g., AD-67, chlorpyrifos, chlorpyrifos and chlorpyrifos), naphthopyrone, naphthalene anhydride (NA) , oxime, phenylpyrimidine, phenylurea, phenylpyrazole compounds, naphthalene anhydride, chloranil, chloranil, piperidine, methoxybenzone, chloranil-mexyl (CGA-185072), 1-dichloroacetylhexahydro-3,3,8α-trimethylpyrrolo[1,2-α]pyrimidin-6-(2H)-one (BAS-145138), dichloromethyl-1,3-dioxolane (MG-191), quinolineoxyacetic acid compounds or their agriculturally acceptable salts, esters or combinations thereof.

[0356] In one embodiment, the composition can exist in any agrochemically suitable form for storage and application to the ground. The composition can be prepared by mixing the active substance in the composition with an inert carrier and adding surfactants and other adjuvants and carriers as needed, and formulated into solid or liquid preparations, including wettable powders (WP), granules (GR), powders, soluble (liquid) concentrates (SL), suspension concentrates (SC), oil-in-water emulsions (EW), water-in-oil emulsions (EO), emulsifiable concentrates (EC), capsule suspensions (CS), mixed preparations of CS and SC preparations (ZC), oil dispersions (OD), other known formulation types or combinations thereof. The composition can also be used to treat plant propagation materials, such as seeds, etc.

[0357] The herbicidal composition of the present disclosure may be present in any conventional agrochemically usable form, for example in the form of a ready-to-use formulation (premix or ready-to-use mixture), or in the form of a tank mix.

[0358] In one embodiment, the compositions / combinations of the present disclosure may be applied pre-emergence or post-emergence. Advantageously, the present combinations provide significant and improved weed control when applied at the post-emergence stage.

[0359] In one embodiment, a method of controlling target weeds comprises applying a premix formulation or tank-mix formulation comprising L-glufosinate, its salts, esters, or combinations thereof and at least one additional herbicide to a desired site.

[0360] In one embodiment, a method of controlling target weeds comprises applying a premix formulation or tank-mix formulation comprising L-glufosinate, its salts, esters, or combinations thereof and at least one additional herbicide to a desired site.

[0361] In one embodiment, the premix or tank-mix formulation comprising L-glufosinate, its salts, esters or combinations thereof and at least one additional herbicide further comprises at least one auxiliary herbicide.

[0362] In one embodiment, each individual composition further comprises at least one agrochemically acceptable excipient / ingredient. The resulting premix or tank-mix of a composition comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide and at least one adjunct herbicide provides a synergistic effect in controlling Amaranth weeds.

[0363] In one embodiment, the herbicide of the combination of the present disclosure can be applied simultaneously as a tank mix or premix, or can be applied sequentially. The sequential application can be immediate and continuous, or it can be timed, and can be carried out in any order deemed effective by those skilled in the art. It can be applied in the soil before plant emergence, before planting or after planting. It can be applied in the soil after plant emergence. It can be applied in the form of foliar spray at different time points during crop development, and can be applied once or multiple times in the early or late stages of emergence. The herbicide composition according to the present disclosure can also be incorporated into the soil before, during or after crop sowing. These combinations can be applied to the site of weeds in a herbicidally effective amount.

[0364] In one embodiment, the combination or composition according to the present disclosure may be used for burndown application or fallow application.

[0365] In one embodiment, the method comprises applying a composition comprising L-glufosinate, its salts, esters, or combinations thereof and at least one additional herbicide as a tank mix.

[0366] In one embodiment, the method comprises applying a composition comprising L-glufosinate, its salts, esters, or combinations thereof and at least one additional herbicide in a premix formulation.

[0367] In one embodiment, the method comprises administering the present combination or composition simultaneously (ie, in combination or separately), or sequentially.

[0368] In one embodiment, the method comprises applying in immediate succession a combination comprising L-glufosinate, its salts, esters, or combinations thereof and at least one additional herbicide.

[0369] In one embodiment, the composition of the present disclosure can be applied in any known manner or conventional method known to those skilled in the art. The non-limiting example of such method includes foliar spraying, substrate peeling, stem injection, drilling and filling method, axe cutting method, cutting stump, cutting and wiping, stem scraper, core application or their combination. The composition of the present disclosure is used in a conventional manner, for example, by watering, spraying, atomizing, dusting or spreading. The composition can be applied to the site by using conventional ground sprayers, particle applicators, watering (soaking), drip irrigation, spraying, atomizing, broadcasting, dusting, foaming, paving, aerial spraying methods, aerial application methods, methods (such as but not limited to drones, robots) using modern technology and other conventional methods known to those skilled in the art.

[0370] In some embodiments, where undesirable and harmful vegetation is treated post-emergence, the compositions disclosed herein are applied by foliar application.

[0371] According to the present disclosure, the method of controlling target weeds can be performed by spraying a suggested tank mix, or a single herbicide can be formulated as a kit containing various components that can be mixed according to instructions before spraying.

[0372] In another embodiment, the present disclosure provides a kit comprising L-phosphinothricin, its salts, esters or combinations thereof and at least one additional herbicide. The kit may also include a component comprising at least one agrochemically acceptable excipient. The kit may also be accompanied by a set of instructions for mixing or using the components provided therein.

[0373] According to one embodiment, the kit comprises:

[0374] (a) L-phosphinothricin, its salts, esters or combinations thereof; and

[0375] (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof; and

[0376] (c) at least one agrochemically acceptable excipient;

[0377] and optionally further comprising:

[0378] (d) Instructions for use.

[0379] According to one embodiment, the kit comprises:

[0380] (a) L-glufosinate ammonium salt;

[0381] (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof; and

[0382] (c) at least one agrochemically acceptable excipient;

[0383] and optionally further comprises:

[0384] (d) Instructions for use.

[0385] In one embodiment, the present disclosure provides a method of increasing crop yield by applying a synergistic herbicide combination comprising L-glufosinate, its salts, esters, or combinations thereof, and at least one additional herbicide described herein.

[0386] In one embodiment, the present disclosure provides a method of improving plant health by applying a synergistic herbicide combination comprising L-glufosinate, its salts, esters, or combinations thereof, and at least one additional herbicide described herein.

[0387] The herbicide combination / composition of the present disclosure is highly safe to crop plants and can control target weeds that cause problems in a wide range from pre-emergence to post-emergence in, for example, rice fields, dry lands or non-agricultural fields.

[0388] In view of the above, it can be seen that several advantages of the present disclosure have been achieved, and the present disclosure has also achieved other favorable results. Although the present disclosure has been fully disclosed, it should be understood that many additional modifications and changes can be made thereto without departing from the scope of the present disclosure. The embodiments can be combined together to better understand the present disclosure without departing from the scope of the present disclosure.

[0389] In another embodiment, the alternative or multiple embodiments disclosed herein should not be understood as limiting. Each embodiment may be cited and claimed individually or in any combination with other embodiments of the present disclosure. Without departing from the scope of the present disclosure, one or more embodiments of the present disclosure may be combined to present the teachings of the present disclosure.

[0390] Since many modifications and variations within the scope of the present disclosure are obvious to those skilled in the art, the present disclosure is described in more detail in the following examples which are merely illustrative. Therefore, the present disclosure should not be limited to the above-mentioned embodiments, methods and the following examples, but should be limited to all embodiments and methods within the scope and spirit of the present invention.

[0391] The following examples illustrate the composition, basic effects and basic methods of the present disclosure.

[0392] Example:

[0393] The following products were used to evaluate the weed control efficacy of this herbicide combination.

[0394] Table 6: Weed control products

[0395]

[0396] Evaluation of post-emergence herbicidal activity:

[0397] method : Trials were conducted to evaluate the efficacy of a combination comprising L-glufosinate and an additional herbicide against Amaranthus weeds.

[0398] The soil used was sandy clay loam - sand: 68.0%; silt: 8.0%; clay: 24.0%.

[0399] All treatments were replicated three times and the spraying volume was 150 L / ha.

[0400] Efficacy evaluation : The expected efficacy of a combination comprising L-glufosinate and an additional herbicide was calculated using the well-established Colby method. Any differences between the observed efficacy and the expected efficacy can be attributed to the synergistic effect exhibited by the combination.

[0401] In the Colby method, the expected (or predicted) response of a herbicide combination is calculated by dividing the product of the observed responses of each component in the combination when applied alone by 100, and then subtracting that value from the sum of the observed responses of each component when applied alone. The unexpected enhancement of the efficacy of the combination can then be determined by comparing the observed combined response with the expected (or predicted) response calculated from the observed responses of each individual component. If the observed combined response is greater than the expected (or predicted) response, or conversely, if the difference between the observed response and the expected response is greater than zero, the combination is said to be synergistic or unexpectedly effective (Colby, SR, Weeds, 1967 (15), pp. 20-22). The Colby method requires only the application of one dose of each herbicide alone and a mixture of two doses. The formula for calculating the expected efficacy (EE), which is compared to the observed efficacy (OE) to determine the efficacy of the present disclosure, is explained here:

[0402] The expected efficacy of the combination of two active ingredients is as follows: EE = (A + B - (A × B) / 100)

[0403] The expected efficacy of the combination of three active ingredients is as follows: EE = A + B + C - (AB + AC + BC) / 100 + ABC / 10,000, where:

[0404] A = observed efficacy of active ingredient A at the same concentration used in the mixture.

[0405] B = observed efficacy of active ingredient B at the same concentration used in the mixture.

[0406] C = the observed efficacy of active ingredient C at the same concentration used in the mixture.

[0407] Example 1: Efficacy of the combination of L-glufosinate ammonium and saflufenacil on Amaranthus avicularis

[0408] Experiments were conducted to evaluate the efficacy of a herbicide combination comprising L-glufosinate-P-ammonium and saflufenacil in controlling green amaranth weeds.

[0409] Table 7 demonstrates the synergistic efficacy observed on weeds using a combination comprising L-glufosinate ammonium and saflufenacil. The percent efficacy was calculated 3 days after application (DAA). The target weed was Amaranthus oleraceus, and the herbicide concentrations and results are recorded in Table 7.

[0410] Table 7: Efficacy observed on Amaranthus chinensis

[0411]

[0412] *Expected efficacy based on Colby's formula

[0413] Thus, it was observed that the application of the herbicide combination comprising L-glufosinate ammonium and saflufenacil had a synergistic effect on the control of green amaranth weeds.

[0414] Example 2: Efficacy of the combination of L-glufosinate ammonium, saflufenacil and triclopyrazone on Amaranthus oleifera

[0415] An experiment was conducted to evaluate the control efficacy of a herbicide combination comprising L-glufosinate ammonium, saflufenacil and triclopyrazone on green amaranth weeds.

[0416] Table 8 demonstrates the synergistic efficacy observed on weeds using a combination comprising L-glufosinate ammonium, saflufenacil and triclopyra. The percent efficacy was calculated after application of 3DAA. The target weed was Amaranthus oleraceus, and the herbicide concentrations and results are recorded in Table 8.

[0417] Table 8: Efficacy observed on Amaranthus chinensis

[0418]

[0419] *Expected efficacy based on Colby's formula

[0420] Thus, it was observed that the application of the herbicide combination comprising L-glufosinate ammonium, saflufenacil and triclopyrazone had a synergistic effect on the control of green amaranth weeds.

[0421] Example 3: Effect of the combination of L-glufosinate ammonium, saflufenacil and 2,4-D choline on Amaranthus avicularis

[0422] An experiment was conducted to evaluate the efficacy of a herbicide combination comprising L-glufosinate ammonium, saflufenacil and 2,4-D choline in controlling green amaranth weeds.

[0423] Table 9 demonstrates the synergistic efficacy observed on weeds using a combination comprising L-glufosinate ammonium, saflufenacil and 2,4-D choline. The percent efficacy was calculated after application of 3DAA. The target weed was Amaranthus oleraceus, and the herbicide concentrations and results are recorded in Table 9.

[0424] Table 9: Efficacy observed on Amaranthus chinensis

[0425]

[0426] *Expected efficacy based on Colby's formula

[0427] Example 4: Effect of the combination of L-glufosinate ammonium and quizalofop-p-ethyl on Amaranthus oleifera

[0428] An experiment was conducted to evaluate the efficacy of a herbicide combination comprising L-glufosinate ammonium and quizalofop-p-ethyl in controlling green amaranth weeds.

[0429] Table 10 demonstrates the synergistic efficacy observed on weeds using a combination comprising L-glufosinate ammonium and quizalofop-p-ethyl. The percent efficacy was calculated after application of 3DAA and 14DAA. The target weed was Amaranthus oleraceus, and the herbicide concentrations and results are recorded in Table 10.

[0430] Table 10: Efficacy observed on Amaranthus chinensis

[0431]

[0432] *Expected efficacy based on Colby's formula

[0433] Example 5: Effect of the combination of L-glufosinate ammonium and succinimidyl on Amaranthus oleifera

[0434] Experiments were conducted to evaluate the efficacy of a herbicide combination comprising L-glufosinate ammonium and sulforaphane on the control of Amaranthus aviculare weeds.

[0435] Table 11 demonstrates the synergistic efficacy observed on weeds using a combination comprising L-glufosinate ammonium and glufosinate-butyl. The percent efficacy was calculated after application of 3DAA and 14DAA. The target weed was Amaranthus oleraceus, and the herbicide concentrations and results are recorded in Table 11.

[0436] Table 11: Efficacy observed on Amaranthus chinensis

[0437]

[0438] *Expected efficacy based on Colby's formula

[0439] Example 6: Effect of the combination of L-glufosinate ammonium and mesotrione on Amaranthus chinensis

[0440] Experiments were conducted to evaluate the efficacy of a herbicide combination comprising L-glufosinate ammonium and mesotrione in controlling Amaranthus rugosa weeds.

[0441] Table 12 demonstrates the synergistic efficacy observed on weeds using a combination comprising L-glufosinate ammonium and mesotrione. The percent efficacy was calculated after application of 3DAA and 7DAA. The target weed was Amaranthus fulvidraco, and the herbicide concentrations and results are recorded in Table 12.

[0442] Table 12: Efficacy observed on Amaranthus cruciferus

[0443]

[0444] *Expected efficacy based on Colby's formula

[0445] Example 7: Effect of the combination of L-glufosinate ammonium, imazapyr and imazapyr on Amaranthus chinensis

[0446] Experiments were conducted to evaluate the efficacy of a herbicide combination comprising L-glufosinate ammonium, imazapyr and imazapyr in controlling Amaranthus fulvidraco weeds.

[0447] Table 13 demonstrates the synergistic efficacy observed on weeds using a combination comprising L-glufosinate ammonium, imazapyr and imazapyr. The percent efficacy was calculated after application of 3DAA. The target weed was Amaranthus fulvidraco, and the herbicide concentrations and results are recorded in Table 13.

[0448] Table 13: Efficacy observed on Amaranthus cruciferus

[0449]

[0450] *Expected efficacy based on Colby's formula

[0451] Thus, the results shown in the examples in Tables 7 to 13 clearly demonstrate the synergistic effect between L-glufosinate ammonium and the additional herbicide. The difference between the observed efficacy and the expected efficacy clearly demonstrates the synergistic effect of the herbicide combination.

Claims

1. A method for controlling weeds by applying a herbicide combination, the herbicide combination comprising: (a) L-phosphinothricin, its salts, esters or combinations thereof; and (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof; The weeds include weeds of the genus Amaranthus.

2. The method according to claim 1, wherein the salt of L-glufosinate is selected from the group consisting of L-glufosinate sodium salt, L-glufosinate potassium salt, L-glufosinate ammonium salt or a combination thereof.

3. The method of claim 1, wherein the combination comprises: (a) L-phosphinothricin, its salts, esters or combinations thereof; and (b) at least one protoporphyrinogen oxidase inhibitor herbicide.

4. The method of claim 3, wherein the combination further comprises at least one auxin mimetic herbicide.

5. The method of claim 1, wherein the combination comprises: (a) L-phosphinothricin, its salts, esters or combinations thereof; and (b) at least one acetyl coenzyme A (CoA) carboxylase inhibitor herbicide.

6. The method of claim 1, wherein the combination comprises: (a) L-phosphinothricin, its salts, esters or combinations thereof; and (b) at least one acetolactate synthase inhibitor herbicide.

7. The method of claim 1, wherein the combination comprises: (a) L-phosphinothricin, its salts, esters or combinations thereof; and (b) at least one hydroxyphenylpyruvate dioxygenase inhibitor herbicide.

8. The method according to claim 1, wherein (a) the protoporphyrinogen oxidase inhibitor herbicide is saflufenacil; (b) the acetyl-CoA carboxylase inhibitor herbicide is selected from the group consisting of quizalofop-p-ethyl, succinimidyl-butyl or a combination thereof; (c) the auxin mimetic herbicide is selected from the group consisting of 2,4-D choline, triclopyr or a combination thereof; (d) the acetolactate synthase inhibitor herbicide is selected from the group consisting of imazapyr, imazapyr or a combination thereof; and (e) The hydroxyphenylpyruvate dioxygenase inhibitor herbicide is mesotrione.

9. The method of claim 1, wherein the weight ratio of L-glufosinate, its salts, esters or combinations thereof to the additional herbicide ranges from about 1:25 to about 25:

1.

10. The method of claim 1, wherein the weight ratio of L-glufosinate, its salts, esters or combinations thereof, the protoporphyrinogen oxidase inhibitor herbicide to the auxin mimetic herbicide ranges from about 1:100:100 to about 100:1:

1.

11. The method of claim 1, wherein the amount of L-glufosinate, its salts, esters, or combinations thereof is in the range of about 100 g ai / L to about 400 g ai / L.

12. The method according to claim 1, wherein (a) the protoporphyrinogen oxidase inhibitor herbicide ranges from about 300 grams of active ingredient per liter to about 1200 grams of active ingredient per liter; (b) the acetyl coenzyme A (CoA) carboxylase inhibitor herbicide ranges from about 5 grams of active ingredient per liter to about 200 grams of active ingredient per liter; (c) the auxin mimetic herbicide ranges from about 100 grams of active ingredient per liter to about 1000 grams of active ingredient per liter; (d) the acetolactate synthase inhibitor herbicide ranges from about 100 grams active ingredient per liter to about 1100 grams active ingredient per liter; and (e) The range of the hydroxyphenylpyruvate dioxygenase inhibitor herbicide is from about 250 grams of active ingredient per liter to about 750 grams of active ingredient per liter.

13. The method of claim 1, wherein L-glufosinate, its salts, esters, or combinations thereof are applied at an application rate of about 50 g ai / hectare to about 350 g ai / hectare.

14. The method according to claim 1, wherein (a) the protoporphyrinogen oxidase inhibitor herbicide is applied at a rate of from about 5 g active ingredient / hectare to about 200 g active ingredient / hectare; (b) the acetyl coenzyme A (CoA) carboxylase inhibitor herbicide is applied at an application rate of about 5 grams of active ingredient per hectare to about 200 grams of active ingredient per hectare; (c) the auxin mimetic herbicide is applied at an application rate of about 50 grams of active ingredient per hectare to about 600 grams of active ingredient per hectare; (d) the acetolactate synthase inhibitor herbicide is applied at an application rate of about 5 grams of active ingredient per hectare to about 100 grams of active ingredient per hectare; and (e) The hydroxyphenylpyruvate dioxygenase inhibitor herbicide is applied at an application rate of about 10 g ai / hectare to about 400 g ai / hectare.

15. The method according to claim 1, wherein the Amaranthus weeds include Amaranthus spinulosus, Amaranthus incisus, Amaranthus scaly, Amaranthus scaly, Amaranthus scaly, Amaranthus scaly, Amaranthus scaly, Amaranthus scaly, Amaranthus californicus, Amaranthus caudatus, Amaranthus chihuahua, Amaranthus pedunculata, Amaranthus rugosa, Amaranthus bulgaricus, Amaranthus scaly, Amaranthus scaly, Amaranthus florida, Amaranthus forked, Amaranthus greek, Amaranthus grandiflora, Amaranthus greggii, Amaranthus spicata, Amaranthus intermittentus, Amaranthus minor, Mitchell's amaranth, Amaranthus obcordatus, Amaranthus palmer, Amaranthus spicata, Amaranthus obcordatus, Amaranthus spicata, Amaranthus spicata, Amaranthus powellii, Amaranthus prausnitzii, Amaranthus dwarfus, Amaranthus broadleaf, Amaranthus retroflexus, Amaranthus salatii, Amaranthus rigidus, Amaranthus rigidus, Amaranthus spinulosa, Amaranthus rhombus leaf, Amaranthus zimbergii, Amaranthus toreii, Amaranthus tricolor, Amaranthus rough fruit, Amaranthus wrinkled fruit, Amaranthus wolkenii, Amaranthus wolkenii, Amaranthus tricolor, Amaranthus rough fruit, Amaranthus rugosa, Amaranthus wolkenii, Amaranthus wolkenii, Amaranthus wolkenii, or a combination thereof.

16. The method of claim 1, wherein the combination provides about 50% to about 100% weed control.

17. A herbicide combination, comprising: (a) L-phosphinothricin, its salts, esters or combinations thereof; and (b) at least one additional herbicide selected from the group consisting of protoporphyrinogen oxidase inhibitor herbicides or combinations thereof; or (c) at least two additional herbicides selected from the group consisting of acetolactate synthase inhibitor herbicides.

18. The combination of claim 17, wherein the combination further comprises at least one additional herbicide selected from the group consisting of auxin mimetic herbicides or combinations thereof.

19. A herbicide composition for controlling weeds of the genus Amaranth, the composition comprising: (a) L-phosphinothricin, its salts, esters or combinations thereof; (b) at least one additional herbicide selected from the group consisting of a protoporphyrinogen oxidase inhibitor herbicide, an acetyl coenzyme A (CoA) carboxylase inhibitor herbicide, an auxin mimetic herbicide, an acetolactate synthase inhibitor herbicide, a hydroxyphenylpyruvate dioxygenase inhibitor herbicide, or a combination thereof; and (c) at least one agrochemically acceptable excipient.

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