Formula for treating gout caused by high uric acid and preparation method thereof

Abstract

The invention discloses a formula for treating gout caused by high uric acid and a preparation method of the formula, belongs to the technical field of traditional Chinese medicines, and aims to solve the problems that the kidney function of a patient is damaged due to side effects of long-term taking of western medicines, gout may be aggravated, and drug-induced kidney function damage is formed. The formula for treating gout caused by high uric acid is prepared from, by weight, 12-30 g of rhizoma smilacis glabrae, 8-18 g of lycopodium clavatum, 8-24 g of yam rhizome, 6-15 g of gentiana macrophylla, 8-20 g of lysimachia christinae hance, 6-15 g of golden cypress, 8-20 g of loranthus parasiticus, 3-12 g of ligusticum wallichii, 15-30 g of plantain herb and 5-15 g of radix clematidis. The traditional Chinese medicine composition is good for regulating damp-heat balance in the body, clearing away heat toxin in the body, helping to regulate yin-yang balance of the body, reducing blood uric acid level and promoting excretion of uric acid, the gentiana macrophylla has the effects of resisting inflammation, easing pain and resisting rheumatism, can relieve arthralgia and swelling, and is suitable for being taken by gout patients for a long time.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, and in particular to a formula for treating gout caused by high uric acid and a preparation method thereof. Background Art

[0002] Gout is a disease state that is rooted in the disorder of purine metabolism and the reduction of uric acid excretion, which together lead to the formation of hyperuricemia in the body. As uric acid levels continue to rise, urate begins to deposit in the joints, soft tissues, cartilage, and kidneys, which in turn causes a series of symptoms, including arthritis, urinary stones, and kidney disease. The medical community has developed a variety of methods for the treatment of gout, among which drug therapy is an important means of treating gout, which is used to relieve pain and inhibit uric acid synthesis or promote uric acid excretion, and reduce urate deposition. However, existing formulas for treating gout caused by high uric acid levels still have certain shortcomings when used.

[0003] The treatment of gout is a comprehensive process, which aims to correct hyperuricemia to prevent the deposition of urate in the joints and kidneys, thereby achieving the goal of preventing recurrence. However, at present, medicine has no specific drugs for the prevention and treatment of gout, and can only temporarily relieve pain. Patients often need to take Western medicine for the treatment of gout for a long time, but these drugs generally have the problems of long-term use, large toxic side effects, high recurrence rate, and less than ideal efficacy. The side effects on the body are far more than the treatment effects, especially the renal damage can aggravate the degree of gout in the later stage, forming drug-induced renal damage, which has a great impact on patients.

[0004] Therefore, we propose a formula for treating gout caused by high uric acid and a preparation method thereof, so as to solve the above-mentioned problems. Summary of the invention

[0005] The purpose of the present invention is to provide a formula for treating gout caused by high uric acid and a preparation method thereof, so as to solve the problems raised by the above-mentioned background technology that the western medicines currently on the market generally have the need for long-term administration, large toxic and side effects, high recurrence rate, and less than ideal therapeutic effects, and the side effects on the body are far more than the therapeutic effects, especially the renal damage can aggravate the degree of gout in the later stage, forming drug-induced renal damage, which has a great impact on patients.

[0006] To achieve the above object, the present invention provides the following technical scheme: a formula for treating gout caused by high uric acid, comprising the following materials in parts by weight: smilax glabra, smilax glabra, radix scutellariae, gentiana macrophyllae, limonene, phellodendron, mistletoe, ligusticum chuanxiong, plantain and clematis;

[0007] The composition and weight of the Chinese medicinal raw materials are as follows: Smilax glabra: 12-30 grams, Herba Lycopodii: 8-18 grams, Herba Dianthus: 8-24 grams, Herba Gentianae: 6-15 grams, Herba Lysimachiae: 8-20 grams, Herba Phellodendri: 6-15 grams, Herba Viscume: 8-20 grams, Rhizoma Chuanxiong: 3-12 grams, Herba Plantaginis: 15-30 grams and Herba Clematis: 5-15 grams.

[0008] Preferably, the formulation for treating gout caused by high uric acid is characterized in that the preparation prepared using the above-mentioned traditional Chinese medicine formulation refers to a decoction, pills, capsules or tablets for oral administration.

[0009] A formula for treating gout caused by high uric acid, wherein the pills are prepared according to the following method:

[0010] S1, respectively taking raw materials such as Smilax glabra, Lycopodiella ciliata, Radix Dioscoreae, Radix Gentianae, Herba Lysimachiae, Cortex Phellodendri, Herba Mori, Rhizoma Chuanxiong, Herba Plantaginis and Radix Clematis for screening, cleaning and sterilization, and using a crushing device to grind the cleaned raw materials into fine powder, and then screening through a sieve;

[0011] S2, put Poria powder, Lysimachia chinensis powder, Radix Gentianae powder, Lysimachia chinensis powder, Cortex Phellodendri powder, Herba Mori Parasitici powder, Rhizoma Chuanxiong powder, Herba Plantaginis powder and Radix Clematis powder into a pill making device in proportion, add auxiliary materials into the pill making device, and keep the stirring speed of the pill making device unchanged during the processing;

[0012] S3, the mixture of drug powder and excipients is kneaded into round pills of suitable hardness and softness in the pill making device, and collected by the collecting device in the pill making machine;

[0013] S4. Place the prepared pills in a cool and ventilated place or drying equipment for drying to remove excess water and moisture. After drying, conduct quality inspection on the prepared pills, and package the qualified pills.

[0014] Preferably, the pill making device comprises a device body, a material storage box is fixedly connected to the upper end of the device body, a material feed port is opened on the device body below the material storage box, and a liquid tank is fixedly connected to the side wall of the device body;

[0015] A double-shaft motor is fixedly arranged at the inner bottom end of the device body, one end of the double-shaft motor extends through the device body, and a first belt is sleeved on the outer side of the extended end of the double-shaft motor, an auger is arranged inside the first belt, and an intermittent feeding mechanism is fixedly connected to the side wall of the auger for realizing intermittent feeding;

[0016] A scraper plate, fixedly arranged in the feed port;

[0017] A discharge port is provided on the side wall of the device body, a rotating roller is rotatably installed in the discharge port, a second belt is sleeved on the outer side of the shaft end of the rotating roller, a reciprocating screw is arranged in the second belt, and a piston rod is sleeved on the outer side of the reciprocating screw;

[0018] The piston cylinder is fixedly arranged in the device body, and a piston sheet is slidably connected in the piston cylinder.

[0019] Preferably, the auger is rotatably arranged in the device body, and the auger corresponds to the feed port, the auger and the dual-axis motor are symmetrically arranged at both ends of the first belt, and a channel is arranged inside the auger, and a liquid outlet connected to the channel is opened on the auger, the end of the auger away from the first belt corresponds to the rotating roller, and an extrusion hole is opened on the device body on the side opposite to the rotating roller and the auger.

[0020] Preferably, the intermittent unloading mechanism comprises a bracket, a moving rod, a rectangular block, a slide groove, a slider, a rotating plate, a driving gear, a connecting frame, a rack, a pull rod, a baffle and a stirring rod;

[0021] A bracket is fixedly arranged on the side wall of the device body above the dual-axis motor, a moving rod is slidably connected in the bracket, and a rectangular block is fixedly connected to the bottom end of the moving rod, a sliding groove is opened on the rectangular block, and a slider is slidably connected in the sliding groove, a rotating plate is fixedly connected to the side wall of the slider, and the rotating plate is fixedly connected to the side wall of the auger;

[0022] A connecting frame is fixedly arranged at the top of the moving rod, one end of the connecting frame away from the moving rod is fixedly connected to a rack, and a pull rod is arranged at the bottom end of the connecting frame, and a baffle is fixedly connected to the bottom end of the pull rod;

[0023] The stirring rod is rotatably arranged in the material storage box, and one end of the stirring rod penetrates and extends out of the material storage box and is fixedly connected with the driving gear.

[0024] Preferably, the baffle is slidably arranged in the device body, and the baffle corresponds to the feed port, and the side wall of the baffle is in contact with the scraper plate, the scraper plate is arranged in an arc-shaped structure, the pull rod on the baffle is slidably connected to the device body, and the pull rod is fixedly connected to the connecting frame, and the rack on the connecting frame is meshed with the driving gear.

[0025] Preferably, the end of the second belt away from the rotating roller is sleeved on the outer side of the shaft end of the dual-axis motor away from the first belt, and two rotating rollers in the second belt are symmetrically arranged about the discharge port, and the two rotating rollers correspond to each other.

[0026] Preferably, the reciprocating screw is rotatably arranged in the device body, and the reciprocating screw is threadedly connected to the piston rod, the piston rod is slidably connected to the device body, and one end of the piston rod corresponds to the piston cylinder, and one end of the piston rod penetrates into the piston cylinder and is fixedly connected to the piston plate.

[0027] Preferably, the water inlet end of the piston cylinder is connected to the liquid tank through a one-way flow pipe, and the water outlet end of the piston cylinder is connected to the internal channel of the auger through a one-way flow pipe, and the pipe and the auger are connected through a rotating joint.

[0028] Compared with the prior art, the invention has the following beneficial effects: the formula for treating gout caused by high uric acid and the preparation method thereof adopt natural Chinese herbal medicine, have less side effects, help regulate the balance of dampness and heat in the body, remove heat toxins in the body, help regulate the balance of yin and yang in the body and reduce the level of blood uric acid, promote the excretion of uric acid, wherein the gentian has anti-inflammatory, analgesic and anti-rheumatic effects, can relieve joint pain and swelling, and is suitable for long-term use by gout patients. The specific contents are as follows:

[0029] 1. By combining the two, Smilax glabra and Gentiana macrophylla can work together to treat the joint pain and swelling caused by gout. It has the effects of promoting dampness and relieving jaundice, lowering uric acid, unblocking meridians and relieving pain, thus enhancing the therapeutic effect. At the same time, combined with Smilax glabra, it can enhance the soothing effect of joints and promote blood circulation around the joints, thereby accelerating the disappearance of inflammation and tissue repair.

[0030] 2. The addition of Centella asiatica, Phellodendron chinense and Ligusticum chuanxiong further enhances the diuretic effect, promotes uric acid excretion, and helps lower blood uric acid levels. The heat-clearing effect of Phellodendron chinense can reduce the inflammatory response around the joints, and the blood-activating effect of Ligusticum chuanxiong can promote local blood circulation, accelerate the disappearance of inflammation and tissue repair, and complement the meridian-clearing and analgesic effects of Smilax glabra and Gentiana macrophylla and the soothing effect of Smilax glabra, making the entire prescription more comprehensive in the treatment of gout and enhancing the overall efficacy. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 This is a schematic diagram of the preparation process of the present invention;

[0032] Figure 2 It is a schematic diagram of the overall structure of the present invention;

[0033] Figure 3 For the present invention Figure 2 The enlarged structural diagram at A in the middle;

[0034] Figure 4 This is a schematic diagram of the axial structure of the present invention;

[0035] Figure 5 For the present invention Figure 4 The enlarged structural diagram at B in the middle;

[0036] Figure 6 It is a schematic diagram of the main cross-sectional structure of the present invention;

[0037] Figure 7 For the present invention Figure 6 The enlarged structural diagram at C in the middle;

[0038] Figure 8 It is a schematic diagram of the internal structure of the present invention.

[0039] In the figure: 1. device body; 101. feed port; 102. discharge port; 2. storage box; 3. liquid tank; 4. double-axis motor; 5. first belt; 6. auger; 601. liquid outlet; 7. intermittent unloading mechanism; 701. bracket; 702. moving rod; 703. rectangular block; 704. slide; 705. slider; 706. rotating plate; 707. driving gear; 708. connecting frame; 709. rack; 710. pull rod; 711. baffle; 712. stirring rod; 8. scraper plate; 9. rotating roller; 10. second belt; 11. reciprocating screw; 12. piston rod; 13. piston plate; 14. piston cylinder; 15. extrusion hole. DETAILED DESCRIPTION

[0040] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0041] The invention provides a technical scheme: a formula for treating gout caused by high uric acid, which is composed of the following materials in parts by weight: smilax glabra, herba striatae, herba striatae, herba chinensis, herba chinensis, herba nephrodisiac, herba phellodendri, herba sansevieriae, herba chuanxiong, herba plantain and herba clematis, wherein the composition and weight of the Chinese medicinal raw materials are: 12-30 grams of smilax glabra, 8-18 grams of herba striatae, 8-24 grams of herba striatae, 6-15 grams of herba chinensis, herba nephrodisiac, 8-20 grams of herba phellodendri, 6-15 grams of herba chinensis, herba sansevieriae, 8-20 grams of herba phellodendri, 3-12 grams of herba chuanxiong, herba plantain and 5-15 grams of herba clematis.

[0042] Embodiment 1

[0043] A formula for treating gout caused by high uric acid, comprising the following components in parts by weight:

[0044] Smilax glabra, 25g, used to reduce uric acid and relieve inflammation and analgesia;

[0045] Herba Lycopodii: 12g, used to improve joint mobility;

[0046] Dioscorea paniculata: 18g, used for the excretion of uric acid and relief of joint pain;

[0047] Gentiana macrophylla: 10g, used to improve joint pain and systemic symptoms caused by gout;

[0048] Centella asiatica: 16g, used for the excretion of uric acid and the disappearance of edema;

[0049] Huangbo: 12g, used to reduce dampness and heat in the body and relieve gout symptoms.

[0050] Mulberry parasite: 15g, used to improve liver and kidney function and enhance body resistance;

[0051] Chuanxiong: 18g, used to reduce pain caused by gout, but the dosage should not be too large;

[0052] Plantain: 20g, used to enhance diuretic effect and promote uric acid excretion;

[0053] Clematis: 10 grams, used to dispel wind and dampness, dredge meridians and relieve pain.

[0054] Auxiliary materials include honey water, syrup, etc., and the added amount is between 10% and 30% of the total weight of the raw materials.

[0055] The preparations prepared using the above-mentioned Chinese medicine formula refer to decoctions, pills, capsules or tablets for oral administration.

[0056] The present technical solution provides a preparation method for a formula for treating gout caused by high uric acid, and the specific steps are as follows:

[0057] S1, respectively taking raw materials such as Smilax glabra, Lycopodiella ciliata, Radix Dioscoreae, Radix Gentianae, Herba Lysimachiae, Cortex Phellodendri, Herba Mori, Rhizoma Chuanxiong, Herba Plantaginis and Radix Clematis for screening, cleaning and sterilization, and using a crushing device to grind the cleaned raw materials into fine powder, and then screening through a sieve;

[0058] S2, put Poria powder, Lysimachia chinensis powder, Radix Gentianae powder, Lysimachia chinensis powder, Cortex Phellodendri powder, Herba Mori Parasitici powder, Rhizoma Chuanxiong powder, Herba Plantaginis powder and Radix Clematis powder into a pill making device in proportion, add auxiliary materials into the pill making device, and keep the stirring speed of the pill making device unchanged during the processing;

[0059] S3, the mixture of drug powder and excipients is kneaded into round pills of suitable hardness and softness in the pill making device, and collected by the collecting device in the pill making machine;

[0060] S4. Place the prepared pills in a cool and ventilated place or drying equipment for drying to remove excess water and moisture. After drying, conduct quality inspection on the prepared pills, and package the qualified pills.

[0061] The pill making device includes a device body 1, a material storage box 2 is fixedly connected to the upper end of the device body 1, and a feed port 101 is opened on the device body 1 below the material storage box 2, and a liquid tank 3 is fixedly connected to the side wall of the device body 1, a double-axis motor 4 is fixedly arranged at the bottom end of the device body 1, one end of the double-axis motor 4 extends through the device body 1, and a first belt 5 is sleeved on the outer side of the extended end of the double-axis motor 4, an auger 6 is arranged in the first belt 5, and an intermittent unloading mechanism 7 is fixedly connected to the side wall of the auger 6 for realizing intermittent feeding, a scraper plate 8 is fixedly arranged in the feed port 101, a discharge port 102 is opened on the side wall of the device body 1, a rotating roller 9 is rotatably installed in the discharge port 102, and a second belt 10 is sleeved on the outer side of the shaft end of the rotating roller 9, and a first belt 10 is sleeved on the outer side of the shaft end of the rotating roller 9. A reciprocating screw 11 is arranged in the second belt 10, and a piston rod 12 is sleeved on the outer side of the reciprocating screw 11, and a piston cylinder 14 is fixedly arranged in the device body 1, and a piston sheet 13 is slidably connected in the piston cylinder 14, and the auger 6 is rotatably arranged in the device body 1, and the auger 6 corresponds to the feed port 101, the auger 6 and the double-axis motor 4 are symmetrically arranged at both ends of the first belt 5, and a channel is arranged inside the auger 6, and a liquid outlet 601 connected to the channel is opened on the auger 6, the end of the auger 6 away from the first belt 5 corresponds to the rotating roller 9, and an extrusion hole 15 is opened on the device body 1 on the side opposite to the rotating roller 9 and the auger 6, and the intermittent unloading mechanism 7 includes a bracket 701, a moving rod 702, a rectangular block 703, a slide groove 704, and a slider 7 05, rotating plate 706, driving gear 707, connecting frame 708, rack 709, pull rod 710, baffle 711 and stirring rod 712, bracket 701, fixedly arranged on the side wall of the device body 1 above the dual-axis motor 4, a moving rod 702 is slidably connected in the bracket 701, and a rectangular block 703 is fixedly connected to the bottom end of the moving rod 702, a slide groove 704 is provided on the rectangular block 703, and a slider 705 is slidably connected in the slide groove 704, a rotating plate 706 is fixedly connected to the side wall of the slider 705, and the rotating plate 706 is fixedly connected to the side wall of the auger 6, a connecting frame 708, fixedly arranged on the top of the moving rod 702, an end of the connecting frame 708 away from the moving rod 702 is fixedly connected to the rack 709, and the bottom end of the connecting frame 708 A pull rod 710 is provided, and a baffle 711 is fixedly connected to the bottom end of the pull rod 710, and a stirring rod 712 is rotatably arranged in the storage box 2, one end of the stirring rod 712 extends through the storage box 2 and is fixedly connected to the driving gear 707, the baffle 711 is slidably arranged in the device body 1, and the baffle 711 corresponds to the feed port 101, and the side wall of the baffle 711 is fitted with the scraper plate 8, and the scraper plate 8 is arranged in an arc-shaped structure, the pull rod 710 on the baffle 711 is slidably connected to the device body 1, and the pull rod 710 is fixedly connected to the connecting frame 708, and the rack 709 on the connecting frame 708 is meshed with the driving gear 707, and the end of the second belt 10 away from the rotating roller 9 is sleeved on the outer side of the shaft end of the double-axis motor 4 away from the first belt 5,Two rotating rollers 9 in the second belt 10 are symmetrically arranged about the discharge port 102, and the two rotating rollers 9 correspond to each other. The reciprocating screw 11 is rotatably arranged in the device body 1, and the reciprocating screw 11 is threadedly connected to the piston rod 12. The piston rod 12 is slidably connected to the device body 1, and one end of the piston rod 12 corresponds to the piston cylinder 14, and one end of the piston rod 12 penetrates and extends into the piston cylinder 14 and is fixedly connected to the piston plate 13. The water inlet end of the piston cylinder 14 is connected to the liquid tank 3 through a one-way flow pipe, and the water outlet end of the piston cylinder 14 is connected to the internal channel of the auger 6 through a one-way flow pipe, and the pipe and the auger 6 are connected through a rotary joint.

[0062] The following also provides the method of use and working steps of the pill making device:

[0063] like Figure 1-Figure 8 As shown, firstly, the powdered Poria cocos powder, Herba Lysimachiae powder, Radix Gentianae powder, Herba Lysimachiae powder, Cortex Phellodendri powder, Herba Moriformis powder, Rhizoma Chuanxiong powder, Herba Plantaginis powder and Herba Clematis powder are sequentially put into the storage box 2 in proportion, and the auxiliary materials are added into the liquid tank 3;

[0064] The double-axis motor 4 is turned on, and the double-axis motor 4 will drive the first belt 5 to rotate, so that the first belt 5 drives the auger 6 to rotate, and then the auger 6 will drive the rotating plate 706 to rotate, so that the rotating plate 706 drives the slider 705 to rotate, so that the slider 705 slides along the slide groove 704, and then drives the rectangular block 703 to move. When the rectangular block 703 moves, it drives the moving rod 702 to move, so that the moving rod 702 drives the connecting frame 708 to move, and the connecting frame 708 pulls the pull rod 710 to move, so that the pull rod 710 drives the baffle 711 to move upward, and the feed port 101 is opened, so that the powder in the storage box 2 enters the device body 1 through the feed port 101, and when the connecting frame 708 moves upward, it drives the rack 709 to move, so that the rack 709 meshes and drives the driving gear 707 to rotate, thereby driving the stirring rod 712 to rotate, so that the stirring rod 712 stirs the powder in the storage box 2 to avoid raw material residue;

[0065] By using the scraper plate 8, when the baffle plate 711 moves upward, the scraper plate 8 can slide against the surface of the baffle plate 711 to scrape off the powder attached to the surface of the baffle plate 711, thereby preventing the powder from adhering to the surface of the baffle plate 711, further improving the practicality of the device. By using the auger 6, the falling raw materials can be transported.

[0066] When the dual-axis motor 4 rotates, it will synchronously drive the second belt 10 to rotate, and the second belt 10 will drive the two rotating rollers 9 and the reciprocating screw 11 to rotate. When the reciprocating screw 11 rotates, it drives the piston rod 12 to move, so that the piston rod 12 pulls the piston plate 13 to reciprocate in the piston cylinder 14, thereby sucking the auxiliary materials in the liquid tank 3 into the piston cylinder 14 through the unidirectional flow pipeline, and then transported to the channel inside the auger 6 by the piston cylinder 14, and then discharged from the liquid outlet 601, and then mixed with the raw materials. As the auger 6 works, the Chinese medicine raw materials mixed with auxiliary materials are squeezed out from the extrusion hole 15, and then fall on the rotating roller 9. Through the rotation of the two rotating rollers 9, they cooperate with each other to rub the extruded Chinese medicine raw materials into pills, and finally discharged from the discharge port 102. After the collection is completed, the next step can be carried out.

[0067] The contents not described in detail in this specification belong to the prior art known to professional and technical personnel in this field.

[0068] Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments, or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A formula for treating gout caused by high uric acid, characterized in that: The invention is composed of the following materials in parts by weight: smilax glabra, smilax glabra, radix scutellariae, gentiana macrophylla, limonia scabra, phellodendron, radix truncatulae, rhizoma chuanxiong, herba plantaine and clematis; The composition and weight of the Chinese medicinal raw materials are as follows: Smilax glabra: 12-30 grams, Herba Lycopodii: 8-18 grams, Herba Dianthus: 8-24 grams, Herba Gentianae: 6-15 grams, Herba Lysimachiae: 8-20 grams, Herba Phellodendri: 6-15 grams, Herba Viscume: 8-20 grams, Rhizoma Chuanxiong: 3-12 grams, Herba Plantaginis: 15-30 grams and Herba Clematis: 5-15 grams.

2. A formula for treating gout caused by high uric acid according to claim 1, characterized in that: The preparations prepared using the above-mentioned Chinese medicine formula refer to decoctions, pills, capsules or tablets for oral administration.

3. A formula for treating gout caused by high uric acid according to claim 2, characterized in that: The pills are prepared as follows: S1, respectively taking raw materials such as Smilax glabra, Lycopodiella ciliata, Radix Dioscoreae, Radix Gentianae, Herba Lysimachiae, Cortex Phellodendri, Herba Mori, Rhizoma Chuanxiong, Herba Plantaginis and Radix Clematis for screening, cleaning and sterilization, and using a crushing device to grind the cleaned raw materials into fine powder, and then screening through a sieve; S2, put Poria powder, Lysimachia chinensis powder, Radix Gentianae powder, Lysimachia chinensis powder, Cortex Phellodendri powder, Herba Mori Parasitici powder, Rhizoma Chuanxiong powder, Herba Plantaginis powder and Radix Clematis powder into a pill making device in proportion, add auxiliary materials into the pill making device, and keep the stirring speed of the pill making device unchanged during the processing; S3, the mixture of drug powder and excipients is kneaded into round pills of suitable hardness and softness in the pill making device, and collected by the collecting device in the pill making machine; S4. Place the prepared pills in a cool and ventilated place or drying equipment for drying to remove excess water and moisture. After drying, conduct quality inspection on the prepared pills, and package the qualified pills.

4. The method for preparing a formula for treating gout caused by high uric acid according to claim 3, characterized in that: The pill making device comprises a device body (1), the upper end of the device body (1) is fixedly connected to a material storage box (2), a material feed port (101) is provided on the device body (1) below the material storage box (2), and a liquid tank (3) is fixedly connected to the side wall of the device body (1); A double-shaft motor (4) is fixedly arranged at the bottom end of the device body (1), one end of the double-shaft motor (4) extends through the device body (1), and a first belt (5) is sleeved on the outer side of the extended end of the double-shaft motor (4), an auger (6) is arranged inside the first belt (5), and an intermittent feeding mechanism (7) is fixedly connected to the side wall of the auger (6) for realizing intermittent feeding; A scraper plate (8) fixedly disposed in the feed port (101); A discharge port (102) is provided on a side wall of the device body (1), a rotating roller (9) is rotatably mounted in the discharge port (102), a second belt (10) is sleeved on the outer side of the shaft end of the rotating roller (9), a reciprocating screw (11) is arranged in the second belt (10), and a piston rod (12) is sleeved on the outer side of the reciprocating screw (11); The piston cylinder (14) is fixedly arranged in the device body (1), and the piston plate (13) is slidably connected in the piston cylinder (14).

5. The method for preparing a formula for treating gout caused by high uric acid according to claim 4, characterized in that: The auger (6) is rotatably arranged in the device body (1), and the auger (6) corresponds to the feed port (101). The auger (6) and the double-axis motor (4) are symmetrically arranged at the two ends of the first belt (5), and a channel is arranged inside the auger (6), and a liquid outlet (601) connected to the channel is opened on the auger (6). The end of the auger (6) away from the first belt (5) corresponds to the rotating roller (9), and an extrusion hole (15) is opened on the device body (1) on the side opposite to the rotating roller (9) and the auger (6).

6. The method for preparing a formula for treating gout caused by high uric acid according to claim 5, characterized in that: The intermittent feeding mechanism (7) comprises a bracket (701), a moving rod (702), a rectangular block (703), a slide groove (704), a slider (705), a rotating plate (706), a driving gear (707), a connecting frame (708), a rack (709), a pull rod (710), a baffle (711) and a stirring rod (712); A bracket (701) is fixedly arranged on the side wall of the device body (1) above the dual-axis motor (4); a moving rod (702) is slidably connected inside the bracket (701); a rectangular block (703) is fixedly connected to the bottom end of the moving rod (702); a sliding groove (704) is provided on the rectangular block (703); a sliding block (705) is slidably connected inside the sliding groove (704); a rotating plate (706) is fixedly connected to the side wall of the sliding block (705); and the rotating plate (706) is fixedly connected to the side wall of the auger (6); A connecting frame (708) is fixedly arranged at the top of the moving rod (702), one end of the connecting frame (708) away from the moving rod (702) is fixedly connected to a rack (709), and a pull rod (710) is arranged at the bottom end of the connecting frame (708), and a baffle (711) is fixedly connected to the bottom end of the pull rod (710); The stirring rod (712) is rotatably disposed in the material storage box (2), and one end of the stirring rod (712) extends through the material storage box (2) and is fixedly connected to the driving gear (707).

7. The method for preparing a formula for treating gout caused by high uric acid according to claim 6, characterized in that: The baffle (711) is slidably arranged in the device body (1), and the baffle (711) corresponds to the feed port (101), and the side wall of the baffle (711) is in contact with the scraper plate (8), and the scraper plate (8) is arranged in an arc-shaped structure. The pull rod (710) on the baffle (711) is slidably connected to the device body (1), and the pull rod (710) is fixedly connected to the connecting frame (708), and the rack (709) on the connecting frame (708) is meshed with the driving gear (707).

8. The method for preparing a formula for treating gout caused by high uric acid according to claim 4, characterized in that: One end of the second belt (10) away from the rotating roller (9) is sleeved on the outer side of the shaft end of the dual-axis motor (4) away from the first belt (5), and two rotating rollers (9) in the second belt (10) are symmetrically arranged about the discharge port (102), and the two rotating rollers (9) correspond to each other.

9. The method for preparing a formula for treating gout caused by high uric acid according to claim 8, characterized in that: The reciprocating screw rod (11) is rotatably arranged in the device body (1), and the reciprocating screw rod (11) is threadedly connected to the piston rod (12), the piston rod (12) is slidably connected to the device body (1), and one end of the piston rod (12) corresponds to the piston cylinder (14), and one end of the piston rod (12) penetrates into the piston cylinder (14) and is fixedly connected to the piston plate (13).

10. The method for preparing a formula for treating gout caused by high uric acid according to claim 9, characterized in that: The water inlet end of the piston cylinder (14) is connected to the liquid tank (3) through a one-way flow pipe, and the water outlet end of the piston cylinder (14) is connected to the internal channel of the auger (6) through a one-way flow pipe, and the pipe and the auger (6) are connected through a rotary joint.

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