An eye health promoting composition containing lutein ester and zeaxanthin

Abstract

The application discloses a health-care composition and belongs to the field of health-care food. The composition contains 1.7-1.9 g of xanthophyll ester, 0.52-0.61 g of corn xanthophyll, 0.35-0.47 g of astaxanthin, 30-60 g of chrysanthemum extract, 40-70 g of celery powder, 30-60 g of Lithocarpus genmssis powder and 110-130 g of sweetening agent per 1000 mL, and the rest is pure water. The composition is prepared by compounding the raw materials, has the effect of significantly relieving visual fatigue and is beneficial to promoting eye health.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of health food, in particular to a composition containing lutein ester and zeaxanthin for promoting eye health. BACKGROUND

[0002] With the change of modern lifestyle, people increasingly rely on electronic screens such as computers, smartphones and other digital devices, which leads to an increasingly serious problem of visual fatigue.

[0003] Visual fatigue is usually caused by the following situations:

[0004] 1. Long time staring at the screen or close eye use leads to insufficient tear secretion, decreased retinal function and causes dry eye;

[0005] 2. Long-term eye use leads to decreased focusing adjustment function, causing myopia, hyperopia or astigmatism and other refractive eye diseases;

[0006] 3. Age increase or chronic disease leads to increased intraocular pressure, increasing the risk of glaucoma;

[0007] 4. Long-term exposure to strong light or blue light, or body aging can cause irreversible damage to the lens, leading to lens aging and cataract formation.

[0008] At present, most of the products for relieving visual fatigue caused by the above reasons are drugs or non-pure traditional Chinese medicine preparations containing compounds, and most consumers have a certain resistance to the use of drugs, so it is of great significance to provide a pure plant extract non-Chinese medicine product that can relieve visual fatigue. SUMMARY

[0009] The purpose of the present application is to provide a composition containing lutein ester and zeaxanthin for promoting eye health, which uses plant ingredients to compound, has high safety, good taste and significant effect of relieving visual fatigue.

[0010] In order to achieve the above purpose, the present application adopts the following technical scheme:

[0011] In the first aspect, the present application provides a composition containing lutein ester and zeaxanthin for promoting eye health, which comprises the following ingredients: lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, Lithocarpus woodii powder, sweetener, pure water.

[0012] Preferably, the composition for promoting eye health is a visual fatigue relieving composition.

[0013] Preferably, the visual fatigue relieving composition contains the following mass components per 1000 mL:

[0014] Lutein ester 1.7-1.9 g, zeaxanthin 0.52-0.61 g, astaxanthin 0.35-0.47 g, chrysanthemum extract 30-60 g, celery powder 40-70 g, Lithocarpus phyllochlamys powder 30-60 g, sweetener 110-130 g, and the balance is pure water.

[0015] The sweetener is selected from one or more of xylitol, maltitol, erythritol, white granulated sugar, sucrose, brown sugar, and honey.

[0016] Most preferably, the eye health promoting composition comprises the following mass components per 1000 mL:

[0017] Lutein ester 1.8 g, zeaxanthin 0.55 g, astaxanthin 0.40 g, chrysanthemum extract 55 g, celery powder 60 g, Lithocarpus phyllochlamys powder 55 g, sweetener 125 g, and the balance is pure water.

[0018] The sweetener is selected from one or more of xylitol, white granulated sugar, and honey.

[0019] In a second aspect, the present application provides a method for preparing the eye health promoting composition of the first aspect, and the specific steps are as follows:

[0020] S1. Weigh lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, Lithocarpus phyllochlamys powder, and sweetener, and perform preliminary food safety inspection;

[0021] S2. Dissolve the sweetener in pure water, then add chrysanthemum extract, celery powder, and Lithocarpus phyllochlamys powder, heat to 60-75°C, and stir until uniform to obtain liquid A;

[0022] S3. Cool liquid A to 25-35°C, add zeaxanthin, astaxanthin, and lutein ester, stir until uniform, and filter to obtain liquid B;

[0023] S4. Perform filling, sterilization, boxing, and warehouse storage of liquid B.

[0024] The filtering step S3 is filtering using a 50-100 micron filter.

[0025] The sterilization step S4 is sterilization using pasteurization or ultra-high temperature instant sterilization.

[0026] The warehouse storage step S4 is storage under normal temperature and light protection.

[0027] Preferably, the method for preparing the eye health promoting composition is a method for preparing an eye strain relieving composition, and the specific steps are as follows:

[0028] S1, take lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, Lithocarpus woodii powder, sweetener, and perform preliminary food safety inspection;

[0029] S2, dissolve the sweetener in pure water, then add the chrysanthemum extract, celery powder, and Lithocarpus woodii powder, heat to 60-75℃, and stir uniformly to obtain liquid A;

[0030] S3, cool liquid A to 25-35℃, add zeaxanthin, astaxanthin, and lutein ester, stir uniformly, filter, and obtain liquid B;

[0031] S4, perform liquid B filling, sterilization, boxing, and storage.

[0032] The S3 filtering step is filtering using a 50-100 micron filter.

[0033] The S4 sterilization is using pasteurization or ultra-high temperature instant sterilization.

[0034] The S4 storage condition is normal temperature and light-proof storage.

[0035] Compared with the prior art, the beneficial effects of the present application are: the present application provides a composition containing lutein ester and zeaxanthin for promoting eye health, and the effect of promoting eye health is specifically relieving visual fatigue, and the composition having the effect of relieving visual fatigue is compounded by lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, Lithocarpus woodii powder, sweetener, and pure water, wherein the soluble fiber in the chrysanthemum extract is fermented by beneficial bacteria in the intestinal tract to produce short-chain fatty acids, the intestinal wall cells are stimulated by the short-chain fatty acids to promote the absorption of nutrients by the intestinal wall cells through G protein-coupled receptors such as GPR43 and GPR41, the short-chain fatty acids also provide energy for the intestinal cells, improve the activity of the intestinal cells, enhance the metabolic activity of the intestinal cells, and promote the absorption of nutrients by the intestinal cells; the non-water-soluble dietary fiber in the celery powder and Lithocarpus woodii powder can promote intestinal peristalsis, enhance intestinal activity, and the quercetin, luteolin, sophorin, apigenin, dihydrochalcone, and vitamin C in the chrysanthemum extract, celery powder, and Lithocarpus woodii powder can help protect intestinal cells from oxidative stress damage, further maintaining the health of intestinal cells; astaxanthin has a certain fishy smell, and the use of astaxanthin together with chrysanthemum extract, celery powder, and Lithocarpus woodii powder can effectively mask the fishy smell, making it easier for users to accept the composition. DETAILED DESCRIPTION

[0036] In order to better understand the present application, the present application will be further described below in conjunction with specific examples, wherein the terms used in the examples are for describing specific specific embodiments and do not constitute a limitation on the scope of protection of the present application.

[0037] The experimental methods in the following examples, unless otherwise specified, are generally carried out according to the conventional conditions, or according to the conditions recommended by the manufacturer. Unless otherwise specified, the percentages and parts are calculated by weight.

[0038] Part of the raw materials and sources are as follows:

[0039] Lutein ester: purchased from Guangdong Mingcheng Biological Technology Co., Ltd.;

[0040] Zeaxanthin: purchased from Guangzhou Huayu Biological Technology Co., Ltd.;

[0041] Astaxanthin: purchased from Guangzhou Huayu Biological Technology Co., Ltd.;

[0042] Chrysanthemum extract: purchased from Guangzhou Huayu Biological Technology Co., Ltd.;

[0043] Celery powder: purchased from Guangzhou Huayu Biological Technology Co., Ltd.;

[0044] Lithocarpus litseifolius powder: purchased from Shaanxi Snoot Biological Technology Co., Ltd.;

[0045] Oatmeal, kale powder, barley leaf powder, soybean powder, pectin powder, bamboo shoot powder, and barley powder: purchased from Guangzhou Huayu Biological Technology Co., Ltd.;

[0046] Xylitol: purchased from Jiangsu Hengxingyuan Food Additives Co., Ltd.;

[0047] White granulated sugar: purchased from Angel E-commerce (Yichang) Co., Ltd.;

[0048] Honey: purchased from Henan Dabieshan Jan Honey Garden Co., Ltd.

[0049] The mass ratio of each component of the 1000 mL of the composition for relieving visual fatigue is shown in Table 1:

[0050] Table 1 Mass ratio of each component of the 1000 mL of the composition for relieving visual fatigue

[0051]

[0052]

[0053] The above-mentioned compositions 1-5 for relieving visual fatigue and the composition for relieving visual fatigue The preparation method is as follows:

[0054] S1, weigh the lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, Lithocarpus litseifolius powder, and sweetener, and perform preliminary food safety inspection;

[0055] S2, dissolve the sweetener in purified water, then add the chrysanthemum extract, celery powder, and Lithocarpus polystachyus Rehd. powder, heat to 65°C, and stir until uniform to obtain liquid A;

[0056] S3, cool liquid A to 30°C, add the corn xanthophyll, astaxanthin, and lutein ester, stir until uniform, pass through a 100-micron bag filter to obtain liquid B;

[0057] S4, fill liquid B into bottles, sterilize using the ultra-high temperature instant sterilization method, pack, store at room temperature, and store in a dark place.

[0058] Relieving visual fatigue composition 6:

[0059] Relieving visual fatigue composition 6 uses the same formula as relieving visual fatigue composition 1, but the preparation method is as follows:

[0060] S1, weigh the lutein ester, corn xanthophyll, astaxanthin, chrysanthemum extract, celery powder, and Lithocarpus polystachyus Rehd. powder, and perform preliminary food safety testing;

[0061] S2, dissolve the sweetener in purified water, then add the chrysanthemum extract, celery powder, and Lithocarpus polystachyus Rehd. powder, heat to 60°C, and stir until uniform to obtain liquid A;

[0062] S3, cool liquid A to 35°C, add the corn xanthophyll, astaxanthin, and lutein ester, stir until uniform, pass through a 50-micron bag filter to obtain liquid B;

[0063] S4, fill liquid B into bottles, sterilize using the pasteurization method, pack, store at room temperature, and store in a dark place.

[0064] Relieving visual fatigue composition 7:

[0065] Relieving visual fatigue composition 7 uses the same formula as relieving visual fatigue composition 1, but the preparation method is as follows:

[0066] S1, weigh the lutein ester, corn xanthophyll, astaxanthin, chrysanthemum extract, celery powder, and Lithocarpus polystachyus Rehd. powder, and perform preliminary food safety testing;

[0067] S2, dissolve the sweetener in purified water, then add the chrysanthemum extract, celery powder, and Lithocarpus polystachyus Rehd. powder, heat to 75°C, and stir until uniform to obtain liquid A;

[0068] S3, cool liquid A to 25°C, add the corn xanthophyll, astaxanthin, and lutein ester, stir until uniform, pass through a 70-micron bag filter to obtain liquid B;

[0069] S4, liquid B is filled, sterilized by ultra-high temperature instant sterilization, boxed, stored in warehouse at room temperature and in dark.

[0070] Relieving visual fatigue composition

[0071] Relieving visual fatigue composition The used composition is the same as the relieving visual fatigue composition 1, except that the preparation method is as follows:

[0072] S1, the lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, Lithocarpus wood extract, sweetener are weighed and subjected to preliminary food safety inspection;

[0073] S2, the sweetener is dissolved in purified water, and then the chrysanthemum extract, celery powder, Lithocarpus wood extract, zeaxanthin, astaxanthin, lutein ester are added, heated to 65℃, stirred uniformly, filtered by a 100 micron bag filter, to obtain liquid A;

[0074] S3, liquid A is filled, sterilized by ultra-high temperature instant sterilization, boxed, stored in warehouse at room temperature and in dark.

[0075] Test 1: duration of photopic vision

[0076] The determination of the duration of photopic vision is carried out according to the "relieving visual fatigue function evaluation method" in the "Notice on the issuance of 9 health function evaluation methods such as antioxidant function evaluation method" (Guo Shiyan Jian Bao Hua (2012) No. 107). The difference in the duration of photopic vision is significant (p<0.05) for the test group itself before and after comparison, and the average duration of photopic vision is increased by more than or equal to 10% for the effective one. The results of the duration of photopic vision are shown in Table 2.

[0077] Table 2: results of the duration of photopic vision

[0078]

[0079] Note: " represents p<0.05. ※

[0080] As can be seen from Table 2, after using the compositions 1-5 provided by the application, the duration of photopic vision is increased by more than 10% compared with the test before itself, which proves that the compositions provided by the application have the function of improving visual fatigue. In addition, from the results of composition 1 and compositions ①-④, it can be known that the efficacy obtained by the application is not caused by simple superposition. Among them, there is a synergistic effect between lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder and Lithocarpus wood extract.

[0081] The composition ​Compared with the results of composition 1, it can be seen that the common dietary fiber cannot achieve the same effect as the equivalent replacement of chrysanthemum extract, celery powder and lithocarpus kawakamii powder in the present application, which may be because the apigenin, flavonoids in celery powder and polysaccharide compounds in chrysanthemum extract and mucilage protein, natural pectin and a certain synergistic effect in lithocarpus kawakamii powder in the composition of the present application, which can promote the absorption of natural active substances by the intestinal wall cells.

[0082] Composition In the composition, although the formula is the same as that of composition 1, the preparation method is different, resulting in a large difference in its effect, which may be because the temperature is too high, resulting in the oxidation of zeaxanthin, astaxanthin and lutein ester, thereby losing activity.

[0083] Test 2: Sensory evaluation test

[0084] Select 4℃, 25℃ and 35℃ environmental temperature for composition 1, 6, 7 and composition Evaluation, every five days to determine the sensory score, a total of 30 days.

[0085] Select 10 people who have been trained in sensory evaluation, according to the scoring standard of table 3, the product is comprehensively evaluated and scored, the final evaluation result is the average value, the sensory evaluation scoring standard is shown in table 3, and the final score average value is shown in table 4.

[0086] Table 3 Sensory evaluation scoring standard

[0087]

[0088]

[0089] Table 4 Sensory evaluation score average value

[0090]

[0091] According to the above scoring standard, the composition 1, 6, 7 scored more than 90 points, while the composition In the sensory evaluation, algae smell appeared, the algae smell of composition ④ was the most, and composition ⑥ appeared bitter taste, composition ⑦ appeared green grass smell, composition ⑧ appeared sticky feeling; Furthermore, composition Obvious precipitation appeared, which may be because the temperature was too high when the raw materials were added, which led to the precipitation of part of the raw materials after cooling, thereby appearing obvious aggregation phenomenon.

[0092] The embodiments described above are only part of the embodiments of the present application, rather than all the embodiments. The detailed description of the embodiments of the present application is not intended to limit the scope of the claimed present application, but only represents selected embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.

Claims

1. A composition containing lutein esters and zeaxanthin to promote eye health, characterized in that, Each 1000 mL of the composition contains the following ingredients by weight: 1.7 g lutein ester, 0.5 g zeaxanthin, 0.4 g astaxanthin, 50 g chrysanthemum extract, 50 g celery powder, 45 g Litsea cubeba powder, 125 g sweetener, and the balance being purified water, wherein the sweetener is xylitol.

2. A method for preparing the composition for promoting eye health as described in claim 1, characterized in that, Specifically, the following steps are included: S1. Weigh out lutein ester, zeaxanthin, astaxanthin, chrysanthemum extract, celery powder, litsea cubeba powder, and sweetener, and conduct preliminary food safety testing. S2. Dissolve the sweetener in purified water, then add chrysanthemum extract, celery powder, and litsea cubeba powder. Heat to 60-75℃ and stir well to obtain liquid A. S3. Cool liquid A to 25-35℃, add zeaxanthin, astaxanthin and lutein ester, stir well and filter to obtain liquid B; S4. Fill, sterilize, pack, and store liquid B.

3. The preparation method according to claim 2, characterized in that, The filtration in step S3 is performed using a 50-100 micron filter.

4. The preparation method according to claim 2, characterized in that, The sterilization in step S4 is performed using pasteurization or ultra-high temperature instantaneous sterilization.

5. The preparation method according to claim 2, characterized in that, The storage conditions in step S4 are room temperature and protection from light.

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