Photophysiotherapy device and apparatus

Abstract

The invention relates to the technical field of medical instruments, in particular to a photophysical therapy device and equipment, and the device comprises at least one light source which is used for emitting spectral radiation of various colors to a target patient; the adjustable frequency control power supply is used for regulating and controlling the radiation frequency of the at least one light source; the power regulator is used for regulating the power of the adjustable frequency control power supply; the stimulation control assembly is used for generating parameter regulation and control instructions of at least one light source, an adjustable frequency control power supply and a power regulator according to the current treatment strategy; the physiological signal sensor is used for collecting an electrophysiological signal generated after the target patient receives the spectral radiation; and the treatment assembly is used for generating a corresponding treatment effect report according to the electrophysiological signal and sending an adjusted treatment strategy to the stimulation control assembly. According to the device, Gamma oscillation in the brain of a patient is induced through sensory stimulation with specific frequency, so that the problems of disease symptoms in the aspects of attention and memory and the like are solved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a photophysical therapy device and equipment. Background Art

[0002] Synapses are the hubs where neurons in the brain transmit information. Neurons can interact with each other through local depolarization of excitatory synapses or hyperpolarization of inhibitory synapses to generate synchronous potentials, which converge into electrical activities that can be detected by microelectrodes, namely local field potentials. In different frequency ranges, local field potentials produce neural oscillations of different properties, which can be divided into delta oscillations (0.1-3 Hz), theta oscillations (4-7 Hz), alpha oscillations (8-12 Hz), beta oscillations (13-24 Hz), gamma oscillations (25-100 Hz), etc. according to different frequencies.

[0003] Among them, Gamma neural oscillation is a high-frequency wave that exists in multiple brain regions such as the thalamus, somatosensory cortex, and hippocampus of animals and humans. It facilitates synaptic plasticity and plays an important role in regulating neural networks. In particular, Gamma neural oscillation plays a vital role in higher-level neural functions such as vision, hearing, and somatosensory sensory feature binding, attention, and memory.

[0004] In terms of attention, the study found that the selective attention shift between visual and auditory modes is accompanied by an increase in the Gamma response in the sensory cortical area. The amplification of Gamma by attention is not unique to the sensory cortex. Transcranial EEG recordings show that in subjects whose attention shifts, there is also Gamma-like activation in the premotor cortex. In the visual spatial attention task experiment, the subjects focus on the visual stimuli that appear on one side of the screen. When the stimulus signal on the attention side appears, there will be an increase in Gamma activity in the contralateral parietal occipital lobe of the attention side. When the space of the visual stimulus on the attention side changes, Gamma activity also increases significantly, indicating that Gamma oscillations are involved in selecting stimuli that match the target.

[0005] In terms of learning and memory, Gamma neural oscillations are involved in regulating the process of synaptic plasticity. In the neurons of the rat visual cortex, when Gamma neural oscillations occur in the brain, neurons show long-term potentiation (LTP) discharge signals. In human experiments, a large number of studies have also confirmed the close relationship between Gamma neural oscillations and long-term memory. EEG, MEG and iEEG have recorded that Gamma neural oscillations can successfully predict the course of long-term memory.

[0006] Similarly, the research team of Li-Huei Tsai, a neuroscientist at the Massachusetts Institute of Technology, used LED light flashes and sound stimulation at a frequency of 40HZ and found that they could induce the generation of Gamma oscillations. This method is called Gamma ENtrainment Using Sensory (GENUS). The team found that GENUS had a positive impact on Alzheimer's disease (AD) and published a series of outstanding studies. 40Hz flash stimulation induced Gamma oscillations can enhance the maze memory of rats, promote the clearance of metabolites of AD mice by microglia, and promote the APQ4 activity of astrocytes in AD mice, thereby promoting the clearance of amyloid Aβ by the glial lymphatic system and delaying the decline of learning and memory in AD mice. At the same time, GENUS has confirmed its safety in a small study of AD patients, as well as its improvement effect on the learning and memory of AD patients.

[0007] In view of the important role of Gamma neural oscillations in attention and memory, and the potential application of sensory stimulation-induced Gamma oscillations in the treatment of neurological diseases, a therapeutic device based on sensory stimulation-induced Gamma oscillations can be proposed, which aims to induce Gamma oscillations in the patient's brain through sensory stimulation of a specific frequency (such as light stimulation, sound stimulation, etc.), thereby improving disease symptoms in terms of attention and memory. Summary of the invention

[0008] The present invention provides a photophysical therapy device and equipment, which induces Gamma oscillations in the patient's brain through sensory stimulation of a specific frequency, thereby improving disease symptoms such as attention and memory.

[0009] A first aspect of the present invention provides a photophysical therapy device, comprising:

[0010] at least one light source for emitting spectral radiation of a plurality of colors toward a target patient;

[0011] An adjustable frequency control power supply, used to adjust the radiation frequency of the at least one light source;

[0012] A power regulator, used to regulate the power of the adjustable frequency controlled power supply;

[0013] a stimulation control component, for generating parameter control instructions for the at least one light source, the adjustable frequency controlled power supply and the power regulator according to a current treatment strategy;

[0014] A physiological signal sensor, used for collecting electrophysiological signals generated by the target patient after receiving spectral radiation;

[0015] The treatment component is used to generate a corresponding treatment effect report according to the electrophysiological signal, adjust the current treatment strategy according to the treatment effect report, and send the adjusted treatment strategy to the stimulation control component.

[0016] Optionally, the at least one light source includes at least two LED lamps, and the at least two LED lamps are evenly arranged in front of both eyes of the target patient to stimulate the retina of the target patient.

[0017] Optionally, the adjustable frequency controlled power supply comprises a frequency synthesizer for generating an adjustable Hertz-level frequency signal.

[0018] Optionally, the physiological signal sensor includes at least one electrode, and the at least one electrode is arranged on the head of the target patient and is used to collect electrophysiological signals generated when the retina of the target patient receives spectral radiation.

[0019] Optionally, the treatment component comprises:

[0020] a data analysis module, configured to evaluate the treatment effect according to the electrophysiological signal and the current state of the target patient to generate the treatment effect report, and to adjust the current treatment strategy according to the treatment effect report to generate the new treatment strategy;

[0021] A database is used to store and manage the treatment effect report, the current treatment strategy, the new treatment strategy, and the parameters of the at least one light source, the adjustable frequency controlled power supply, and the power regulator.

[0022] Optionally, it also includes:

[0023] An image display is used to display the treatment report and allow manual adjustment of parameters of the at least one light source, the adjustable frequency controlled power supply and the power regulator according to the adjusted treatment strategy.

[0024] Optionally, it also includes:

[0025] The communication component is used to realize wireless communication between the treatment component and the stimulation control component and the physiological signal sensor.

[0026] A second aspect of the present invention provides a photophysical therapy device, comprising: the photophysical therapy device as described above and a wearable body on which the photophysical therapy device is disposed.

[0027] The photophysical therapy device and equipment proposed in the embodiments of the present invention can provide diagnosis and treatment functions at the same time, evaluate the treatment effect through physiological signals, and adjust the treatment parameters according to the evaluation results; according to the specific situation and treatment needs of the user, it can provide personalized treatment plans, including the adjustment of parameters such as spectral composition, power, stroboscopic and treatment time; it can monitor the physiological signal parameters during the treatment process in real time, and provide feedback and adjustment suggestions as needed; it can store and manage the user's treatment data, including stimulation methods, physiological signals and treatment effects, etc., to provide a basis for subsequent research and analysis.

[0028] Additional aspects and advantages of the present invention will be given in part in the following description and in part will be obvious from the following description, or will be learned through practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] The above and / or additional aspects and advantages of the present invention will become apparent and easily understood from the following description of the embodiments in conjunction with the accompanying drawings, in which:

[0030] Figure 1 A block diagram of a photophysical therapy device provided by an embodiment of the present invention;

[0031] Figure 2 A schematic diagram of the specific structure of a photophysical therapy device provided by an embodiment of the present invention;

[0032] Figure 3 A block diagram of a photophysical therapy device provided by an embodiment of the present invention;

[0033] Figure 4 A schematic diagram of a photophysical therapy device provided by an embodiment of the present invention;

[0034] Figure 5 A schematic diagram of another photophysical therapy device provided by an embodiment of the present invention.

[0035] Description of reference numerals:

[0036] 10-optical physical therapy device, 1-at least one light source, 2-adjustable frequency control power supply, 3-power regulator, 4-stimulation control component, 5-physiological signal sensor, 6-treatment component, 61-data analysis module, 62 database, 7-image display, 8-communication component, 30-optical physical therapy equipment and 31-wearable body. DETAILED DESCRIPTION

[0037] Embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0038] The following describes the photophysical therapy device and equipment according to the embodiments of the present invention with reference to the accompanying drawings.

[0039] Figure 1 A block diagram of a photophysical therapy device provided by an embodiment of the present invention.

[0040] like Figure 1 and 2 As shown, the photophysical therapy device 10 includes: at least one light source 1, an adjustable frequency controlled power supply 2, a power regulator 3, a stimulation control component 4, a physiological signal sensor 5 and a treatment component 6.

[0041] Among them, at least one light source 1 is used to emit spectral radiation of multiple colors to the target patient. The adjustable frequency control power supply 2 is used to adjust the radiation frequency of at least one light source 1. The power regulator 3 is used to adjust the power of the adjustable frequency control power supply 2. The stimulation control component 4 is used to generate parameter control instructions for at least one light source 1, the adjustable frequency control power supply 2 and the power regulator 3 according to the current treatment strategy. The physiological signal sensor 5 is used to collect the electrophysiological signals generated by the target patient after receiving the spectral radiation. The treatment component 6 is used to generate a corresponding treatment effect report based on the electrophysiological signal, adjust the current treatment strategy according to the treatment effect report, and send the adjusted treatment strategy to the stimulation control component 4.

[0042] In some embodiments, at least one light source 1 in the embodiments of the present invention includes at least two LED lamps, and the at least two LED lamps are evenly arranged in front of the eyes of the target patient. To meet different treatment needs, the at least two LED lamps provide multi-color spectral radiation to the eyes according to the current treatment strategy to stimulate the retina of the target patient.

[0043] In some embodiments, the adjustable frequency controlled power supply 2 in the embodiments of the present invention includes a frequency synthesizer for generating an adjustable Hertz-level frequency signal. To meet different treatment needs, the frequency synthesizer provides multi-adjustable frequency flash radiation to at least one light source 1, so that at least one light source 1 emits spectral radiation of multiple colors to the target patient.

[0044] In some embodiments, the power regulator 3 in the embodiment of the present invention adjusts the intensity and power of light emitted by at least one light source 1 and an adjustable frequency control power source 2 according to the current treatment strategy, thereby controlling the intensity of the spectral radiation and the stimulation degree of the radiation frequency.

[0045] In some embodiments, the stimulation control component 4 in the embodiment of the present invention generates parameter control instructions according to the current treatment strategy, and performs parameter control on at least one light source 1, adjustable frequency control power supply 2, and power regulator 3 according to the parameter control instructions.

[0046] In some embodiments, the physiological signal sensor 5 includes at least one electrode, which is arranged on the head of the target patient and is used to collect the electrophysiological signal generated by the retina of the target patient after receiving spectral radiation, and send the electrophysiological signal to the treatment component 6.

[0047] In some embodiments, the treatment component 6 includes: a data analysis module 61 and a database 62, wherein:

[0048] The data analysis module 61 is used to evaluate the treatment effect of the obtained electrophysiological signals and the current state of the target patient using a preset artificial intelligence analysis method under the stimulation of the current treatment strategy, so as to find the sensitive frequencies between different users, generate a treatment effect report, and adjust the current treatment strategy according to the treatment effect report to generate a new treatment strategy that is more suitable for the state of the target patient after stimulation;

[0049] The database 62 is used to store and manage treatment effect reports, current treatment strategies, new treatment strategies, and parameters of at least one light source 1 , an adjustable frequency controlled power source 2 , and a power regulator 3 .

[0050] In some embodiments, it also includes:

[0051] The image display 7 is used to provide an intuitive operating interface, which can display treatment reports and allow manual adjustment of parameters of at least one light source 1, adjustable frequency control power supply 2 and power regulator 3 according to the adjusted treatment strategy (i.e., new treatment strategy), so as to facilitate users to set treatment parameters and view treatment progress and results.

[0052] In some embodiments, it also includes:

[0053] The communication component 8 is used to realize wireless communication between the treatment component 6 and the stimulation control component 4 and the physiological signal sensor 5.

[0054] The working principle of the photophysical therapy device proposed in the embodiment of the present invention is as follows: at least one light source 1 emits spectral radiation of multiple colors to the retina of the target patient according to the conventional treatment strategy, the physiological signal sensor 5 collects the electrophysiological signal generated by the target patient after receiving the spectral radiation, the treatment component 6 analyzes the electrophysiological signal, generates a corresponding treatment effect report, and adjusts the conventional treatment strategy according to the treatment effect report, and sends the adjusted treatment strategy to the stimulation control component 4, the stimulation control component 4 generates parameter control instructions for at least one light source 1, the adjustable frequency control power supply 2 and the power regulator 3 according to the adjusted treatment strategy, and uses the parameter control instructions to control the at least one light source 1, the adjustable frequency control power supply 2 and the power regulator 3. The parameters are adjusted, the adjusted power regulator 3 adjusts the power of the adjustable frequency control power supply 2, the adjusted adjustable frequency control power supply 2 regulates the radiation frequency of at least one light source 1, the adjusted at least one light source 1 adjusts the spectral radiation corresponding to multiple colors and emits it to the retina of the target patient, the physiological signal sensor 5 collects new treatment strategies again, iterates the above process, stimulates the retina with modulated light, and uses specific frequencies, rotation methods, different frequencies of visible light during the day or infrared light at night to produce therapeutic effects for neurodegenerative diseases AD, mental diseases (such as depression), autoimmune diseases (such as psoriasis, lupus erythematosus), which can be widely used in the medical field, especially in geriatric diseases, rehabilitation treatment, pain management, etc. The biological effect channel of the device is: from light---retina---whole brain neural resonance (brain waves of different frequencies)---regulate immune cells (neuroglia)---expel malignant lesions (such as amyloid deposits of AD, etc.).

[0055] In summary, the photophysical therapy device proposed in the embodiment of the present invention has the following beneficial effects:

[0056] (1) It can provide both diagnostic and therapeutic functions, evaluate the therapeutic effect through physiological signals, and adjust the therapeutic parameters based on the evaluation results.

[0057] (2) According to the user's specific situation and treatment needs, it can provide personalized treatment plans, including the adjustment of parameters such as spectral composition, power, stroboscopic frequency and treatment time;

[0058] (3) Ability to monitor physiological signal parameters during treatment in real time and provide feedback and adjustment suggestions as needed.

[0059] (4) It can store and manage the user's treatment data, including stimulation methods, physiological signals, and treatment effects, providing a basis for subsequent research and analysis.

[0060] Next, the photophysical therapy device according to the embodiment of the present invention will be described with reference to the accompanying drawings.

[0061] Figure 3 4 is a block diagram of a photophysical therapy device according to an embodiment of the present invention.

[0062] like Figure 3 As shown, the optical physical therapy device 30 includes: an optical physical therapy device 10 and a wearable body 31, wherein Figure 4 and 5 As shown, the wearable body 31 can be a glasses frame type or a VR glasses type, etc., and the photophysical therapy device 10 is set in the wearable body 31 to facilitate the patient to wear it.

[0063] It should be noted that the above explanations of the photophysical therapy device embodiment are also applicable to the photophysical therapy equipment of this embodiment and will not be repeated here.

[0064] The optical physical therapy device proposed in the embodiment of the present invention has the following beneficial effects:

[0065] (1) It can provide both diagnostic and therapeutic functions, evaluate the therapeutic effect through physiological signals, and adjust the therapeutic parameters based on the evaluation results.

[0066] (2) According to the user's specific situation and treatment needs, it can provide personalized treatment plans, including the adjustment of parameters such as spectral composition, power, stroboscopic frequency and treatment time;

[0067] (3) Ability to monitor physiological signal parameters during treatment in real time and provide feedback and adjustment suggestions as needed.

[0068] (4) It can store and manage the user's treatment data, including stimulation methods, physiological signals, and treatment effects, providing a basis for subsequent research and analysis.

[0069] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or N embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0070] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present invention, the meaning of "N" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

Claims

1. A photophysical therapy device, characterized in that: include: at least one light source for emitting spectral radiation of a plurality of colors toward a target patient; An adjustable frequency control power supply, used to adjust the radiation frequency of the at least one light source; A power regulator, used to regulate the power of the adjustable frequency controlled power supply; a stimulation control component, for generating parameter control instructions for the at least one light source, the adjustable frequency controlled power supply and the power regulator according to a current treatment strategy; A physiological signal sensor, used for collecting electrophysiological signals generated by the target patient after receiving spectral radiation; The treatment component is used to generate a corresponding treatment effect report according to the electrophysiological signal, adjust the current treatment strategy according to the treatment effect report, and send the adjusted treatment strategy to the stimulation control component.

2. The photophysical therapy device according to claim 1, characterized in that: The at least one light source includes at least two LED lamps, and the at least two LED lamps are evenly arranged in front of both eyes of the target patient to stimulate the retina of the target patient.

3. The photophysical therapy device according to claim 1, characterized in that: The adjustable frequency controlled power supply includes a frequency synthesizer for generating an adjustable Hertz-level frequency signal.

4. The photophysical therapy device according to claim 1, characterized in that: The physiological signal sensor includes at least one electrode, which is arranged on the head of the target patient and is used to collect electrophysiological signals generated when the retina of the target patient receives spectral radiation.

5. The photophysical therapy device according to claim 1, characterized in that: The treatment component comprises: a data analysis module, configured to evaluate the treatment effect according to the electrophysiological signal and the current state of the target patient to generate the treatment effect report, and to adjust the current treatment strategy according to the treatment effect report to generate a new treatment strategy; A database is used to store and manage the treatment effect report, the current treatment strategy, the new treatment strategy, and the parameters of the at least one light source, the adjustable frequency controlled power supply, and the power regulator.

6. The photophysical therapy device according to claim 1, characterized in that: Also includes: An image display is used to display the treatment report and allow manual adjustment of parameters of the at least one light source, the adjustable frequency controlled power supply and the power regulator according to the adjusted treatment strategy.

7. The photophysical therapy device according to claim 1, characterized in that: Also includes: The communication component is used to realize wireless communication between the treatment component and the stimulation control component and the physiological signal sensor.

8. A photophysical therapy device, characterized in that: include: A photophysical therapy device as described in any one of claims 1 to 7 and a wearable body provided with the same.

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