Thrombus aspiration catheter

Abstract

The embodiment of the invention provides a thrombus aspiration catheter which comprises a first catheter body, and one port of the first catheter body is rotationally connected with an aspiration tube coaxial with the first catheter body; the suction pipe is provided with an annular guide cavity with an opening facing the first pipe body. A plurality of flexible pieces which are distributed in the circumferential direction of a pipe opening and limited to be capable of opening towards the interior of the pipe opening in a one-way mode are arranged at the pipe opening of the suction pipe. The second pipe body is limited in relative rotation but can be sleeved with the first pipe body in a relative sliding mode in the axial direction, and one end of the second pipe body is inserted into the guide cavity. The rotary guide mechanism comprises a spiral guide part and a sliding part which is combined with the guide part in a sliding fit manner; the sliding part is formed at one end of the second tube body inserted into the guide cavity; wherein the edges of the plurality of flexible sheets form a stirring part, and the stirring part is used for stirring and dispersing the contacted thrombus when the stirring part is in an open state and is driven to rotate by the relative sliding of the first tube body and the second tube body. The rotation guiding mechanism can drive the suction pipe to rotate and move outwards.

Description

Technical Field

[0001] The present disclosure relates to the technical field of medical devices, and in particular to a thrombus aspiration catheter. Background Art

[0002] Intracranial vascular intervention surgery is one of the important means of treating cerebrovascular diseases, among which the stent thrombus removal combined with aspiration catheter technology is widely used in the treatment of acute ischemic stroke. However, most aspiration catheters in the prior art are only suitable for stent entry to pull the thrombus into the aspiration catheter. However, when the existing aspiration catheter is used to aspirate the thrombus, a large thrombus is easily stuck in the tube mouth and cannot be smoothly aspirated out of the blood vessel through the aspiration catheter. It is also easy for part of the thrombus in the catheter to flow back due to the blockage of the tube mouth, thereby increasing the risk of distal embolism. Summary of the invention

[0003] In view of the above-mentioned shortcomings of the prior art, the purpose of the present disclosure is to provide a thrombus aspiration catheter to solve the problems in the related art.

[0004] The present disclosure provides a thrombus aspiration catheter in a first aspect, comprising: A first tube body, wherein a suction tube coaxially connected to one end thereof is rotatably connected thereto; the suction tube is provided with a guide cavity in an annular shape and opening toward the first tube body; a plurality of flexible sheets distributed along the circumference of the tube mouth and restricted to be able to open unidirectionally into the tube mouth are provided at the tube mouth of the suction tube; wherein the plurality of flexible sheets form a corresponding opening of the tube mouth in response to the suction force inside the first tube body; A second tube body is restricted from relative rotation but can be relatively slidably fitted into the first tube body along the axial direction, and one end of the second tube body is inserted into the guide cavity; A rotating guide mechanism comprises a spiral guide portion and a sliding portion slidably coupled to the guide portion; the guide portion is formed on the wall of the guide cavity and extends spirally around the central axis of the suction tube; the sliding portion is formed at one end of the second tube body inserted into the guide cavity; wherein the edges of the multiple flexible sheets form a stirring portion for stirring up the contacted thrombus when the device is in an open state and driven to rotate by the relative sliding of the first tube body and the second tube body.

[0005] In an embodiment of the first aspect, the stirring portion is in an acute angle shape with an angle ranging from 10 degrees to 45 degrees.

[0006] In an embodiment of the first aspect, the manner in which the first tube body and the second tube body generate axial relative movement is implemented as follows: the first tube body slides relative to the second tube body.

[0007] In an embodiment of the first aspect, a guide unit is further included; the guide unit includes a guide groove and a guide block that are slidably combined; the guide groove is formed on the inner wall of the second tube body and extends along the axis of the second tube body, and the guide block is arranged on the inner wall of the first tube body.

[0008] In an embodiment of the first aspect, one of the walls of the first tube body and the suction tube that are in contact with each other forms an annular groove, and the other forms an annular block slidably engaged in the groove.

[0009] In an embodiment of the first aspect, the guide portion is implemented as being recessed on the guide cavity wall, and the sliding portion is convexly disposed on the second tube body wall; and / or, the guide portion is implemented as being convexly disposed on the guide cavity wall, and the sliding portion is recessed on the second tube body wall.

[0010] In an embodiment of the first aspect, an angle between the flexible sheet and the inner wall of the suction tube when the flexible sheet is in an open state is negatively correlated with a magnitude of the suction force inside the second tube body.

[0011] In an embodiment of the first aspect, the flexible sheet includes a fixing portion and a shielding portion; the fixing portion is connected to the inner wall of the suction tube.

[0012] In an embodiment of the first aspect, an unopened stent assembly is inserted into the interior of the second tube body, and the stent assembly is released after penetrating or passing through a thrombus to form a state capable of driving the thrombus, so that when the multiple flexible sheets open the tube opening, the released stent assembly can pull the thrombus out of the blood vessel from the tube opening.

[0013] In an embodiment of the first aspect, a plurality of the flexible sheets are arranged on the inner wall of the suction tube with a spacing between them and the tube opening.

[0014] As described above, the embodiment of the present disclosure provides a thrombus aspiration catheter, which includes a first tube body, a second tube body and a rotation guide mechanism. A coaxial aspiration tube is rotatably connected to one end of the first tube body; the aspiration tube is provided with a ring-shaped guide cavity with an opening facing the first tube body; the tube mouth of the aspiration tube is provided with a plurality of flexible sheets distributed along the circumference of the tube mouth and limited to be able to open unidirectionally into the tube mouth; wherein the plurality of flexible sheets form a corresponding opening of the tube mouth in response to the suction force inside the first tube body. The second tube body is limited to relative rotation but can be relatively slidably fitted in the first tube body along the axial direction, and one end is inserted into the guide cavity. The rotation guide mechanism includes a spiral guide portion and a sliding portion slidably combined with the guide portion; the guide portion is formed on the wall surface of the guide cavity in a spiral extension around the central axis of the aspiration tube; the sliding portion is formed at one end of the second tube body inserted into the guide cavity; wherein the edges of the plurality of flexible sheets form a stirring portion, which is used to stir the contacted thrombus when it is in an open state and driven to rotate by the relative sliding of the first tube body and the second tube body. The advantage of the above arrangement is that when the first tube body and the second tube body move axially relative to each other, the rotation guide mechanism can drive the suction tube to rotate and move outward, so that the flexible sheet can disperse the thrombus at the tube mouth, and eat away at the larger thrombus and remove it from the blood vessel. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 is a schematic diagram of the flexible sheet in a closed state in an embodiment of the present disclosure; Figure 2 , which is a schematic diagram of another viewing angle when the flexible sheet is in a closed state in the embodiment of the present disclosure; Figure 3 , which is a schematic diagram showing that the flexible sheet is in an open state and cooperates with the bracket assembly in an embodiment of the present disclosure; Figure 4 , which is a schematic diagram of another viewing angle when the flexible sheet in the embodiment of the present disclosure is in an open state; Figure 5 The embodiment of the present disclosure is shown in Figure 1 A magnified view of middle; Figure 6 FIG. 1 is a schematic diagram of the structure of a thrombus aspiration catheter in another embodiment of the present disclosure; Figure 7 FIG. 1 is a schematic structural diagram of a thrombus aspiration catheter from another perspective in another embodiment of the present disclosure; Figure 8 FIG. 1 is a schematic structural diagram of another embodiment of the present disclosure in which the tube mouth of the thrombus aspiration catheter is opened; Fig. 9 FIG. 1 is a structural schematic diagram of another embodiment of the present disclosure in which the tube mouth of the thrombus aspiration catheter is opened from another perspective; Fig.10FIG. 1 is a schematic diagram of the structure of the thrombus aspiration catheter and the stent assembly in another embodiment of the present disclosure; Fig.11 Shown in is a structural schematic diagram of another state of cooperation between the thrombus aspiration catheter and the stent assembly in another embodiment of the present disclosure. DETAILED DESCRIPTION

[0016] The following is an explanation of the embodiments of the present disclosure by specific examples, and those skilled in the art can easily understand other advantages and effects of the present disclosure from the information disclosed by the present disclosure. The present disclosure can also be implemented or applied through other different specific embodiments, and the details in the present disclosure can also be modified or changed in various ways according to different viewpoints and application modules without departing from the spirit of the present disclosure. It should be noted that the embodiments in the present disclosure and the features in the embodiments can be combined with each other without conflict.

[0017] The following is a detailed description of the embodiments of the present disclosure with reference to the accompanying drawings so that those skilled in the art can easily implement the present disclosure. The present disclosure can be embodied in many different forms and is not limited to the embodiments described herein.

[0018] In the representations of the present disclosure, the reference terms "one embodiment", "some embodiments", "examples", "specific examples", or "some examples" and the like mean that the specific features, structures, materials or characteristics represented in conjunction with the embodiment or example are included in at least one embodiment or example of the present disclosure. Moreover, the specific features, structures, materials or characteristics represented may be combined in any one or a group of embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine different embodiments or examples represented in the present disclosure and the features of different embodiments or examples, unless they are mutually contradictory.

[0019] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the features. In the representation of the present disclosure, "a group" means two or more, unless otherwise clearly and specifically defined.

[0020] In order to clearly describe the present disclosure, components not related to the description are omitted, and the same reference numerals are given to the same or similar components throughout the specification.

[0021] Throughout the specification, when a device is said to be "connected" to another device, this includes not only the case of "direct connection" but also the case of "indirect connection" by placing other elements therebetween. In addition, when a device is said to "include" a certain component, unless otherwise stated, it does not exclude other components, but means that other components may be included.

[0022] Although the terms first, second, etc. are used to represent various elements in this article in some examples, these elements should not be limited by these terms. These terms are only used to distinguish one element from another element. For example, the first interface and the second interface, etc. are represented. Moreover, as used in this article, the singular forms "one", "one" and "the" are intended to also include plural forms, unless there is an opposite indication in the context. It should be further understood that the terms "comprising" and "including" indicate that there are the described features, steps, operations, elements, modules, projects, kinds, and / or groups, but do not exclude the existence, occurrence or addition of one or a group of other features, steps, operations, elements, modules, projects, kinds, and / or groups. The terms "or" and "and / or" used herein are interpreted as inclusive, or mean any one or any combination. Therefore, "A, B or C" or "A, B and / or C" means "any of the following: A; B; C; A and B; A and C; B and C; A, B and C". Only when the combination of elements, functions, steps or operations is inherently mutually exclusive in some way, will there be an exception to this definition.

[0023] The technical terms used herein are only used to refer to specific embodiments and are not intended to limit the present disclosure. The singular form used herein also includes the plural form unless the sentence clearly indicates the contrary meaning. The meaning of "including" used in the specification is to specify specific characteristics, regions, integers, steps, operations, elements and / or components, and does not exclude the existence or addition of other characteristics, regions, integers, steps, operations, elements and / or components.

[0024] Although not defined differently, all terms, including technical and scientific terms used herein, have the same meaning as those generally understood by those skilled in the art to which the present disclosure belongs. Terms defined in commonly used dictionaries are additionally interpreted as having meanings consistent with relevant technical literature and the message of the present disclosure, and shall not be overly interpreted as ideal or very formal meanings unless defined.

[0025] Intracranial vascular intervention surgery is one of the important means of treating cerebrovascular diseases, among which the stent thrombus removal combined with aspiration catheter technology is widely used in the treatment of acute ischemic stroke. However, most aspiration catheters in the prior art are only suitable for stent entry to pull the thrombus into the aspiration catheter. However, when the existing aspiration catheter is used to aspirate the thrombus, a large thrombus is easily stuck in the tube mouth and cannot be smoothly aspirated out of the blood vessel through the aspiration catheter. It is also easy for part of the thrombus in the catheter to flow back due to the blockage of the tube mouth, thereby increasing the risk of distal embolism.

[0026] Based on the above problems, when the first tube body and the second tube body in the embodiment of the present disclosure move axially relative to each other, the rotation guide mechanism can drive the suction tube to rotate and move outward, so that the flexible sheet can disperse the thrombus at the tube mouth, and eat away at the larger thrombus and remove it from the blood vessel through the catheter.

[0027] Figure 1 ] is a schematic diagram of the flexible sheet in a closed state in an embodiment of the present disclosure. Figure 2 FIG. 8 is a schematic diagram showing another perspective of the flexible sheet in a closed state in an embodiment of the present disclosure. Figure 3 FIG. 1 is a schematic diagram showing an embodiment of the present disclosure in which the flexible sheet is in an open state and cooperates with the bracket assembly. Figure 4 FIG. 8 is a schematic diagram showing another viewing angle of the flexible sheet in the embodiment of the present disclosure when the flexible sheet is in an open state. Figure 5 The embodiment of the present disclosure is shown in Figure 1 A magnified view of the middle. Figure 1 , 2 , 3, 4 and Figure 5 In the example, the thrombus aspiration catheter includes a first tube body 40, a second tube body 50 and a rotation guide mechanism 60. A coaxial aspiration tube 70 is rotatably connected to one end of the first tube body 40; the aspiration tube 70 is provided with a guide cavity 701 which is annular and opens toward the first tube body 40; a plurality of flexible sheets 71 are provided at the tube mouth 702 of the aspiration tube 70, which are distributed along the circumference of the tube mouth 702 and are limited to be able to open unidirectionally into the tube mouth 702; wherein the plurality of flexible sheets 71 form a corresponding opening of the tube mouth 702 in response to the internal suction of the first tube body 40.

[0028] The second tube body 50 is restricted from relative rotation but can be relatively slidably fitted into the first tube body 40 along the axial direction, and one end of the second tube body 50 is inserted into the guide cavity 701 .

[0029] The rotating guide mechanism 60 includes a spiral guide portion 61 and a sliding portion 62 slidably coupled to the guide portion 61; the guide portion 61 is formed on the wall of the guide cavity 701 and extends spirally around the central axis of the suction tube 70; the sliding portion 62 is formed at one end of the second tube body 50 inserted into the guide cavity 701; wherein the edges of the multiple flexible sheets 71 form a stirring portion 711, which is used to stir up the contacted thrombus when it is in an open state and driven to rotate by the relative sliding of the first tube body 40 and the second tube body 50.

[0030] The advantage of the above arrangement is that when the first tube body 40 and the second tube body 50 move axially relative to each other, the rotation guide mechanism 60 can drive the suction tube 70 to rotate and move outward, so that the flexible sheet 71 can disperse the thrombus at the tube mouth, thus eroding and removing the larger thrombus from the blood vessel.

[0031] exist Figure 5 In the example, the guide portion 61 is implemented as being recessed on the wall surface of the guide cavity 701, and the sliding portion 62 is convexly disposed on the wall surface of the second tube body 50. Exemplarily, the sliding portion 62 is combined with the end or middle portion of the guide portion 61 close to the first tube body 40. In another embodiment, the guide portion 61 is implemented as being convexly disposed on the wall surface of the guide cavity 701, and the sliding portion 62 is recessed on the wall surface of the second tube body 50.

[0032] Exemplarily, the flexible sheet 71 includes a fixing portion 712 and a shielding portion 713; the fixing portion 712 is connected to the inner wall of the tube body. The stirring portion 711 is in an acute angle shape, and the angle range is 10 degrees to 45 degrees. It can be understood that the acute angle shape can increase the sharpness of the stirring portion 711, so as to effectively cut the contacted thrombus in the open state. Further exemplary, the stirring portion 711 is formed at the edge of the shielding portion 713 of the flexible sheet 71.

[0033] Exemplarily, when the flexible sheet 71 is in the open state, the angle between the flexible sheet 71 and the inner wall of the suction tube 70 is negatively correlated with the suction force inside the second tube body 50 .

[0034] Exemplarily, the manner in which the first tube body 40 and the second tube body 50 generate axial relative movement is implemented as follows: the first tube body 40 slides relative to the second tube body 50. It can be understood by those skilled in the art that after the second tube body 50 is connected to the negative pressure device, when the flexible sheet 71 is needed to disperse the thrombus, the operator increases the negative pressure inside the second tube body 50 to increase the opening of the flexible sheet 71, so that a part of the larger thrombus enters the tube mouth 702 of the suction tube 70; and then reduces the negative pressure of the second tube body 50, so that the flexible sheet 71 can contact the thrombus entering the tube mouth 702 of the suction tube 70. At this time, the operator keeps the second tube body 50 stationary and pulls the first tube body 40 outward, and the first tube body 40 drives the suction tube 70 to move outward. While the suction tube 70 moves outward, the suction tube 70 rotates under the cooperation of the guide portion 61 and the sliding portion 62, so that the suction tube 70 moves outward through the stirring portion 711 of the flexible sheet 71 to pull the thrombus while rotating to cut the thrombus, thereby stirring and dislodging part of the thrombus from the larger thrombus. Then the first tube body 40 is pushed inward to reset the suction tube 70 to its original position, and when the thrombus enters the tube opening 702 of the suction tube 70 again, the above process is repeated.

[0035] exist Figure 1 and Figure 5 In the example, the thrombus aspiration catheter further includes a guide unit 80; the guide unit 80 includes a guide groove 81 and a guide block 82 that are slidably coupled; the guide groove 81 is formed along the outer wall of the second tube body 50 and extends along the axis of the second tube body 50, and the guide block 82 is provided on the inner wall of the first tube body 40. It can be understood that the guide unit 80 can make the first tube body 40 and the second tube body 50 only move relative to each other in the axial direction, but not rotate relative to each other. This prevents the rotation guide mechanism 60 from losing its function due to the relative rotation of the first tube body 40 and the second tube body 50.

[0036] exist Figure 5 In the example, one of the walls of the first tube body 40 and the suction tube 70 that are in contact with each other forms an annular groove 401, and the other forms an annular block 72 that is slidably coupled to the groove 401. In this embodiment, the groove 401 is formed on the wall of the first tube body 40, and the annular block 72 is provided on the wall of the suction tube 70. It can be understood that the combination of the annular block 72 and the groove 401 not only realizes the connection between the first tube body 40 and the suction tube 70, but also enables the rotation of the first tube body 40 and the suction tube 70. Exemplarily, the cross-sectional shape of the groove 401 and the annular block 72 is implemented as a three-quarter circle. In another embodiment, the cross-sectional shape of the groove 401 and the annular block 72 is implemented as an inverted T shape.

[0037] exist Figure 3 In the example, the unopened stent assembly 30 is inserted into the interior of the second tube body 50, and the stent assembly 30 is released after entering or passing through the thrombus to form a state that can drive the thrombus, so that when the multiple flexible sheets 71 open the tube opening 702, the released stent assembly 30 can pull the thrombus out of the blood vessel from the tube opening 702. Exemplarily, the stent assembly 30 includes a microcatheter 31 and a stent 32 inserted in the microcatheter 31.

[0038] Another embodiment of the present disclosure provides an operation method, which is applied to the thrombus aspiration catheter, and includes the following steps: S101: placing the tube openings of the tube bodies of the plurality of flexible sheets close to the thrombus under the guidance of a guide wire; S102: another tube opening of the second tube body is connected to an external negative pressure device, the plurality of flexible sheets no longer cover the tube opening, and the finely divided thrombus enters the interior of the tube body through the tube opening under negative pressure suction; S103: When the tube opening is blocked by a thrombus, the plurality of flexible sheets resume covering the tube opening due to the absence of a continuous negative pressure inside the second tube body, thereby preventing the thrombus that has entered the second tube body from flowing back into the blood vessel and causing distal embolism; S104: disconnecting the second tube from the external negative pressure device; the stent assembly passes through the second tube and opens the tube opening after the first end abuts against the plurality of flexible sheets, thereby penetrating the thrombus; S105: retaining the stent and withdrawing the microcatheter into the second tube body, and the stent separated from the microcatheter is expanded and immersed in the thrombus; S106: After the stent is fully embedded in the thrombus, the second tube body is connected to the external negative pressure device again, and the negative pressure is appropriately increased to increase the degree to which the plurality of flexible sheets open the tube openings; S107: slowly and synchronously pull the microcatheter and the stent, and the stent drives the thrombus to slowly pass through the opened tube mouth; in this process, when the thrombus partially enters the interior of the suction tube and reaches the position of contacting the flexible sheet, keep the stent stationary and drive the first tube body to slide relative to the second tube body, so that the suction tube rotates and drives the multiple flexible sheets to stir up part of the thrombus located in the tube mouth when moving outward; at the same time, the suction tube is driven outward to a state where the inner cavity of the suction tube is connected to the blood vessel, so that the stirred thrombus can be sucked out of the body by the second tube body; when it is necessary to stir up part of the thrombus again to reduce the volume of the thrombus, push the first tube body inward until the suction tube is in the original position, and repeat this step; S108: pulling the stent until the disrupted thrombus can be completely incorporated into the suction tube, so that after the thrombus passes over the plurality of flexible sheets, the plurality of flexible sheets re-cover the tube opening to prevent the thrombus in the suction tube from flowing back; S109: When stent thrombus removal is required, S104 to S108 are repeated; if not required, the first tube body and the second tube body are removed, and the suction is terminated.

[0039] Figure 6 Shown in FIG. 1 is a schematic structural diagram of a thrombus aspiration catheter in another embodiment of the present disclosure. Figure 7 Shown in is a schematic structural diagram of a thrombus aspiration catheter from another perspective in another embodiment of the present disclosure. Figure 8 FIG. 8 is a schematic structural diagram of another embodiment of the present disclosure in which the tube mouth of the thrombus aspiration catheter is opened. Fig. 9 ] is a structural schematic diagram of another embodiment of the present disclosure in which the tube mouth of the thrombus aspiration catheter is opened from another perspective.

[0040] exist Figure 6 , 7 , 8 and Fig. 9 In the example, the thrombus aspiration catheter includes a tube body 10, wherein a plurality of flexible sheets 71A are provided at one tube opening 702A of the tube body 10, which are distributed circumferentially along the tube opening 702A and are restricted to be opened unidirectionally into the tube opening 702A; wherein the plurality of flexible sheets 71A close the tube opening 702A when there is no suction inside the tube body 10; and open the tube opening 702A when there is suction inside the tube body 10.

[0041] The advantage of the above arrangement is that after the other tube opening 702A of the tube body 10 is connected to the negative pressure device, there is suction inside the tube body 10, and the plurality of flexible sheets 71A open the tube opening 702A when there is suction inside the tube body 10. At this time, part of the thrombus can be sucked into the tube body 10 through the tube opening 702A in the open state. When the tube opening 702A is blocked by the thrombus, the plurality of flexible sheets 71A re-cover the tube opening 702A due to the continuous suction of the internal objects of the tube body 10, thereby preventing the thrombus that has entered the tube body 10 from flowing back into the blood vessel. The time and energy consumed in dealing with the thrombus backflow are reduced, and the efficiency of the operation is improved.

[0042] Fig.10 Shown in FIG. 1 is a schematic structural diagram of the cooperation between a thrombus aspiration catheter and a stent assembly in another embodiment of the present disclosure. Fig.11 FIG. 1 is a schematic diagram showing another state of cooperation between a thrombus aspiration catheter and a stent assembly in another embodiment of the present disclosure. Fig.10 and Fig.11In the example, the inside of the tube body 10 is provided with an unopened stent assembly 30, and the stent assembly 30 is provided to be released after penetrating or passing through a thrombus to form a state capable of driving the thrombus, so that when the plurality of flexible sheets 71A open the tube opening 702A, the thrombus is pulled out of the blood vessel from the tube opening 702A by the applied force portion. Exemplarily, the stent assembly 30 includes a microcatheter 31 and a stent 32 penetrating the microcatheter 31.

[0043] exist Figure 7 In the example, the flexible sheet 71A includes a fixing portion 712A and a shielding portion 713A. The fixing portion 712A is connected to the inner wall of the tube body 10. The shielding portions 713A of the plurality of flexible sheets 71A cover the tube opening 702A together.

[0044] Exemplarily, the number of the flexible sheets 71A is four, and the four flexible sheets 71A are arranged on the inner wall of the nozzle 702A in a circumferentially distributed manner along the nozzle 702A. In another embodiment, the number of the flexible sheets 71A is three or five, but not limited thereto, and the plurality of flexible sheets 71A can completely cover the nozzle 702A in the initial state.

[0045] Further illustratively, the shielding portions 713A of the plurality of flexible sheets 71A partially overlap. It is understandable that the partially overlapping plurality of flexible sheets 71A can further improve the coverage of the tube opening 702A, thereby improving the effect of the plurality of flexible sheets 71A in blocking the thrombus from flowing back through the tube opening 702A.

[0046] exist Figure 8 In the example, the opening degree of the tube opening 702A is positively correlated with the magnitude of the suction force inside the tube body 10. It can be understood by those skilled in the art that, as the suction force inside the tube body 10 increases, the swing amplitude of the shielding portions 713A of the plurality of flexible sheets 71A into the tube increases, so that the gaps between the plurality of flexible sheets 71A increase, thereby increasing the opening degree of the tube opening 702A, and facilitating the passage of the remaining thrombus in the subsequent process.

[0047] exist Figure 6 and Figure 8 In the example, a plurality of the flexible sheets 71A are arranged on the inner wall of the tube body 10 with a spacing between the tube opening 702A. The advantage of such arrangement is that when the tube opening 702A is blocked by a thrombus, the thrombus can be partially stuck in the space between the plurality of the flexible sheets 71A and the tube opening 702A, so as to further improve the stability between the thrombus and the tube body 10.

[0048] Exemplarily, the flexible sheet 71A is made of medical silicone or the same material as a biological valve. Exemplarily, the outer wall of the tube body 10 is coated with a hydrophilic coating; the hydrophilic coating is implemented as polyvinyl pyrrolidone. Further exemplary, the inner diameter of the tube body 10 is 1.11 mm to 1.73 mm.

[0049] Another embodiment of the present disclosure provides an operation method, which is applied to the thrombus aspiration catheter, and includes the following steps: S201: placing the tube openings of the tube bodies of the plurality of flexible sheets close to the thrombus under the guidance of a guide wire; S202: another tube opening of the tube body is connected to an external negative pressure device, the plurality of flexible sheets no longer cover the tube opening, and the broken thrombus enters the interior of the tube body through the tube opening under negative pressure suction; S203: When the tube opening is blocked by a thrombus, the plurality of flexible sheets resume covering the tube opening due to the absence of a continuous negative pressure inside the tube body, thereby preventing the thrombus that has entered the tube body from flowing back into the blood vessel and causing distal embolism; S204: disconnecting the tube body from the external negative pressure device; the stent assembly passes through the tube body and opens the tube opening after the first end abuts against the plurality of flexible sheets, thereby penetrating the thrombus; S205: retaining the stent and withdrawing the microcatheter into the interior of the tube body, and the stent separated from the microcatheter is expanded and immersed in the thrombus; S206: After the stent is fully embedded in the thrombus, the tube body is connected to the external negative pressure device again, and the negative pressure is appropriately increased to increase the degree to which the multiple flexible sheets open the tube openings; S207: slowly and synchronously pull the microcatheter and the stent, so that the stent drives the thrombus to slowly pass through the opened tube opening; S208: After the thrombus completely enters the tube body and passes over the plurality of flexible sheets, the plurality of flexible sheets re-cover the tube opening to prevent the thrombus inside the tube body from flowing back; S209: When stent thrombus removal is required, S204 to S208 are repeated; if not, the tube body is removed and the suction is terminated.

[0050] Exemplarily, another operating method in yet another embodiment of the present disclosure is implemented to include the following steps: S301: The tube body is guided by the guide wire so that the tube openings where the multiple flexible sheets are located are close to the thrombus; S302: the other tube opening of the tube body is connected to the external negative pressure device, and the shielding parts of the plurality of flexible sheets swing toward the other tube opening under the action of negative pressure to generate gaps and open the tube opening; the finely divided thrombus enters the interior of the tube body through the gaps at the tube opening under the suction of negative pressure; S303: When the tube opening is blocked by a thrombus, the shielding parts of the plurality of flexible sheets swing back to cover the tube opening because negative pressure cannot be continuously formed inside the tube body, thereby preventing the thrombus that has entered the tube body from flowing back into the blood vessel and causing distal embolism; S304: disconnecting the tube body from the external negative pressure device; after the microcatheter and the stent are inserted into the tube body and abut against the plurality of flexible sheets at the head end, the external microcatheter drives the shielding portion of the flexible sheet to swing slightly toward the thrombus due to the friction between the outer wall of the microcatheter and the shielding portion of the flexible sheet, until the microcatheter and the stent penetrate the blocked thrombus; S305: Keeping the stent in the blood vessel and slowly withdrawing the microcatheter, the microcatheter drives the shielding portion of the flexible sheet to swing slightly toward the other tube opening due to the friction between the outer wall of the microcatheter and the shielding portion of the flexible sheet, and after the microcatheter is out of contact with the flexible sheet, the shielding portion of the flexible sheet abuts against the guide wire connected to the stent; S306: The stent is deployed and embedded in the thrombus after being freed from the microcatheter. S307: Perform angiography to observe whether the stent is in a suitable position; if the position is suitable, stay for five minutes to allow the stent to fit tightly with the thrombus; if the position is not suitable, adjust the position of the stent; S308: The tube body is connected to the external negative pressure device again, and the negative pressure is appropriately increased, so that the shielding parts of the plurality of flexible sheets are deflected to another tube opening by the negative pressure, thereby increasing the degree to which the plurality of flexible sheets open the tube opening; S309: slowly and synchronously pulling the microcatheter and the stent, after the microcatheter enters the tube body, the stent drives the thrombus to slowly pass through the tube opening with a higher degree of opening; S310: After the stent drives the thrombus to completely enter the interior of the tube body and pass over the plurality of flexible sheets, the plurality of flexible sheets swing back to cover the tube opening because the interior of the tube body behind the stent cannot continuously form negative pressure, thereby preventing the thrombus that has entered the tube body from flowing back into the blood vessel and causing distal embolism; S311: When stent thrombus removal is required, S304 to S310 are repeated; if not, the tube body is removed and the suction is terminated.

[0051] In summary, the embodiment of the present disclosure provides a thrombus aspiration catheter, which includes a first tube body, a second tube body and a rotation guide mechanism. A coaxial aspiration tube is rotatably connected to one end of the first tube body; the aspiration tube is provided with a ring-shaped guide cavity with an opening facing the first tube body; the tube mouth of the aspiration tube is provided with a plurality of flexible sheets distributed along the circumference of the tube mouth and limited to be able to open unidirectionally into the tube mouth; wherein the plurality of flexible sheets form a corresponding opening of the tube mouth in response to the suction force inside the first tube body. The second tube body is limited to relative rotation but can be relatively slidably fitted in the first tube body along the axial direction, and one end is inserted into the guide cavity. The rotation guide mechanism includes a spiral guide portion and a sliding portion slidably combined with the guide portion; the guide portion is formed on the wall surface of the guide cavity in a spiral extension around the central axis of the aspiration tube; the sliding portion is formed at one end of the second tube body inserted into the guide cavity; wherein the edges of the plurality of flexible sheets form a stirring portion, which is used to stir the contacted thrombus when it is in an open state and driven to rotate by the relative sliding of the first tube body and the second tube body. The advantage of the above arrangement is that when the first tube body and the second tube body move axially relative to each other, the rotation guide mechanism can drive the suction tube to rotate and move outward, so that the flexible sheet can disperse the thrombus at the tube mouth, and eat away at the larger thrombus and remove it from the blood vessel through the catheter.

[0052] The above embodiments are merely illustrative of the principles and effects of the present disclosure, and are not intended to limit the present disclosure. Anyone familiar with the technology may modify or change the above embodiments without violating the spirit and scope of the present disclosure. Therefore, all equivalent modifications or changes made by those with ordinary knowledge in the technical field without departing from the spirit and technical ideas disclosed in the present disclosure shall still be covered by the protection scope of the present disclosure.

Claims

1. A thrombus aspiration catheter, characterized in that: include: A first tube body, wherein a suction tube coaxially connected to one end thereof is rotatably connected thereto; the suction tube is provided with a guide cavity in an annular shape and opening toward the first tube body; a plurality of flexible sheets distributed along the circumference of the tube mouth and restricted to be able to open unidirectionally into the tube mouth are provided at the tube mouth of the suction tube; wherein the plurality of flexible sheets form a corresponding opening of the tube mouth in response to the suction force inside the first tube body; A second tube body is restricted from relative rotation but can be relatively slidably fitted into the first tube body along the axial direction, and one end of the second tube body is inserted into the guide cavity; A rotating guide mechanism comprises a spiral guide portion and a sliding portion slidably coupled to the guide portion; the guide portion is formed on the wall of the guide cavity and extends spirally around the central axis of the suction tube; the sliding portion is formed at one end of the second tube body inserted into the guide cavity; wherein the edges of the multiple flexible sheets form a stirring portion for stirring up the contacted thrombus when the device is in an open state and driven to rotate by the relative sliding of the first tube body and the second tube body.

2. The thrombus aspiration catheter according to claim 1, characterized in that: The stirring portion is in an acute angle shape, and the angle range is 10 degrees to 45 degrees.

3. The thrombus aspiration catheter according to claim 1, characterized in that: The manner in which the first tube body and the second tube body generate axial relative movement is implemented as follows: the first tube body slides relative to the second tube body.

4. The thrombus aspiration catheter according to claim 1, characterized in that: It also includes a guide unit; the guide unit includes a guide groove and a guide block that are slidably combined; the guide groove is formed on the inner wall of the second tube body and extends along the axis of the second tube body, and the guide block is arranged on the inner wall of the first tube body.

5. The thrombus aspiration catheter according to claim 1, characterized in that: One of the walls where the first tube body and the suction tube are in contact forms an annular groove, and the other forms an annular block slidably engaged in the groove.

6. The thrombus aspiration catheter according to claim 1, characterized in that: The guide portion is implemented as being recessed on the guide cavity wall, and the sliding portion is convexly disposed on the second tube body wall; and / or, the guide portion is implemented as being convexly disposed on the guide cavity wall, and the sliding portion is recessed on the second tube body wall.

7. The thrombus aspiration catheter according to claim 1, characterized in that: The angle between the flexible sheet and the inner wall of the suction tube when the flexible sheet is in the open state is negatively correlated with the magnitude of the suction force inside the second tube body.

8. The thrombus aspiration catheter according to claim 1, characterized in that: The flexible sheet includes a fixing portion and a shielding portion; the fixing portion is connected to the inner wall of the suction pipe.

9. The thrombus aspiration catheter according to claim 1, characterized in that: An unopened stent assembly is inserted into the interior of the second tube body, and the stent assembly is released after penetrating or passing through a thrombus to form a state capable of driving the thrombus, so that when the multiple flexible sheets open the tube opening, the released stent assembly can pull the thrombus out of the blood vessel from the tube opening.

10. The thrombus aspiration catheter according to claim 1, characterized in that: A plurality of the flexible sheets are arranged on the inner wall of the suction pipe with a spacing between them and the pipe opening.

Images