Anti-wrinkle composition as well as application and cosmetic thereof

By combining the functional factors of various plant extracts with the Extreme Spirulina extract and the European Aquamarine bud solution and adding the resveratrol solution to form a new anti-wrinkle composition, the limitations of the existing anti-wrinkle composition in improving the skin's anti-wrinkle effect and preventing skin aging, achieving more significant anti-wrinkle effect and aging protection.

CN119632907AActive Publication Date: 2025-03-18GUANGZHOU MEIZI BIOTECHNOLOGY CO LTD

Patent Information

Application Number
CN202411979793.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-31
Publication Date
2025-03-18
Estimated Expiration
2044-12-31

AI Technical Summary

Technical Problem

The existing anti-wrinkle compositions have limitations in improving the anti-wrinkle effect of the skin, and it is difficult to effectively prevent skin aging.

Method used

By combining the functional factors of a variety of plant extracts with the Extreme Spirulina Extract and the Euro-Aquarium Bud Solution and adding the resveratrol solution, a new anti-wrinkle composition is formed to enhance anti-wrinkle effect and prevent skin aging.

Benefits of technology

This composition significantly improves the anti-wrinkle effect of the skin, can more effectively prevent skin aging, and improves skin elasticity and firmness by removing free radicals and inhibiting elastase.

✦ Generated by Eureka AI based on patent content.

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Patent Text Reader

Abstract

The invention belongs to the field of cosmetics, and discloses an anti-wrinkle composition and application thereof.The anti-wrinkle composition comprises functional factors, a spirulina maxima extract and an European glauca bud solution, and the mass ratio of the functional factors to the spirulina maxima extract to the European glauca bud solution is (5-7): (0.5-1.5): (0.01-0.1); the anti-wrinkle effect of the composition is synergistically improved by matching functional factors containing various plant extracts with the spirulina maxima extract and the euonymus japonicus bud solution; in addition, the invention further discloses a cosmetic which contains 1-30 wt% of the anti-wrinkle composition.
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Description

Technical Field

[0001] The present invention relates to the field of cosmetics, and in particular to an anti-wrinkle composition and application thereof, and cosmetics. Background Art

[0002] Human skin aging refers to the phenomenon that the skin's external morphology, internal structure and function decline under the influence of exogenous or endogenous factors. There are many factors that cause skin aging, among which oxidation is a very important factor. Oxidation is the price of oxygen for the human body to breathe, and oxidation will produce free radicals that cause aging. Free radicals are an important factor that causes skin damage and aging. Excessive accumulation of free radicals can cause damage to the skin, mainly manifesting as a series of aging manifestations such as loss of softness and elasticity, wrinkles, dryness, keratinization, dullness, and excessive deposition of reduced / oxidized glutathione and lipofuscin.

[0003] Chinese patent application 202311538944.X discloses a moisturizing, anti-wrinkle, soothing and firming composition and a cream containing the composition, wherein the composition consists of saffron extract, carnation flower extract, Spirulina maxima extract, a moisturizer and a solvent.

[0004] In this solution, saffron extract, carnation flower extract, Spirulina superba extract and moisturizer are used in a synergistic combination to achieve a synergistic effect, which is beneficial for the composition to better hydrate and moisturize the skin, and is beneficial for better skin absorption of water, resulting in better deep hydration effect on the skin.

[0005] However, the present application has found through research that when Spirulina maxima extract is combined with Fagus sylvatica bud solution and functional factors containing Thyme extract, Myrtlesia odorifera leaf extract, Hibiscus sabdariffa flower extract, Honeysuckle flower extract, and Ganoderma lucidum extract, it also has a good anti-wrinkle effect on the skin.

[0006] The problem to be solved by this proposal is: how to propose an anti-wrinkle composition different from the prior art. Summary of the invention

[0007] To solve the above problems, the present invention provides an anti-wrinkle composition and its use and cosmetics, which form a composition with good anti-wrinkle effect by combining functional factors containing multiple plant extracts with Spirulina maxima extract and Fagus sylvatica bud solution, and combining the composition with resveratrol solution can further enhance the anti-wrinkle effect of the composition and prevent skin aging.

[0008] To achieve the above-mentioned purpose, the present application discloses an anti-wrinkle composition, which contains functional factors, spirulina maxima extract, and European Fagus sylvatica bud solution, and the mass ratio of the functional factors, spirulina maxima extract, and European Fagus sylvatica bud solution is 5-7: 0.5-1.5: 0.01-0.1;

[0009] The functional factor is prepared by mixing water, butylene glycol, thyme extract, mirabilis leaf extract, roselle flower extract, honeysuckle flower extract, black ganoderma extract, 1,2-hexanediol and ethylhexylglycerin in a mass ratio of 55-60:28-32:1:1-3:1-3:1-3:1-3:0.8-1.2:0.1.

[0010] The functional factors contain five kinds of plant extracts: thyme extract, mirabilis leaf extract, roselle flower extract, honeysuckle flower extract, and black ganoderma extract. Thyme extract has skin-revitalizing and anti-wrinkle properties, can promote the production of fibrin, inhibit the activity of elastase and collagenase, and thus help maintain the elasticity and firmness of the skin.

[0011] The extract of Milo leaf is rich in natural and effective antioxidants such as polyphenols and flavonoids, which can prevent free radical damage to the skin, slow down the skin aging process, and balance the skin's pigmentation and spots;

[0012] Roselle flower extract is rich in anthocyanins, vitamin C and other antioxidant substances, which can remove free radicals in the body, delay cell aging, and keep the skin elastic and shiny;

[0013] The biflavonoids contained in honeysuckle flower extract have excellent antioxidant and anti-aging effects, which can help remove free radicals and delay skin aging;

[0014] The polysaccharides and polypeptides in the black ganoderma extract have a significant anti-aging effect, can promote and adjust immune function, regulate metabolic balance, promote the synthesis of nucleic acids and proteins, and resist and remove free radicals in the body.

[0015] Spirulina Maxima is rich in beta-carotene, vitamin E, gamma-linolenic acid, superoxide dismutase and other bioactive substances, which can remove free radicals and effectively delay the aging process of cells. At the same time, it can also improve skin vitality, improve dullness and yellowness caused by fatigue, and make the skin look healthier and more radiant.

[0016] European Fagus sylvatica bud solution can accelerate the entry of oxygen into the skin, stimulate the energy of skin cells, and restore cell vitality. This process also helps increase protein synthesis, making the skin rejuvenated and smoothing wrinkles;

[0017] The anti-wrinkle effect of the composition can be synergistically enhanced by combining the functional factors, Spirulina maxima extract and Fagus sylvatica bud solution.

[0018] Preferably, the composition further contains a resveratrol solution, and the mass ratio of the resveratrol solution to the Fagus sylvatica bud solution is 0.001-0.1:0.01-0.1.

[0019] In addition, the invention also discloses the use of the anti-wrinkle composition in preparing cosmetics.

[0020] In addition, a cosmetic is disclosed, wherein the cosmetic contains 1 to 30 wt % of the anti-wrinkle composition.

[0021] Preferably, the cosmetic further contains a skin conditioner, a moisturizer, an emulsifier, an antioxidant, and a thickener, and the mass ratio of the skin conditioner, moisturizer, emulsifier, antioxidant, and thickener is 1-1.5:9-11:0.4-0.6:0.4-0.6:0.05-0.15.

[0022] Preferably, the skin conditioning agent is selected from at least one of niacinamide, arginine / lysine polypeptide solution, and ergothioneine;

[0023] The moisturizing agent is selected from at least one of butylene glycol, methyl gluceth-20, glycerin, dipropylene glycol, trehalose, 1,2-hexanediol, and sodium hyaluronate;

[0024] The emulsifier is selected from at least one of polysorbate-20 and PEG-40 hydrogenated castor oil;

[0025] The antioxidant is p-hydroxyacetophenone;

[0026] The thickener is selected from at least one of carbomer, acrylic acid (esters) / C10-30 alkyl acrylate cross-linked polymer and xanthan gum.

[0027] Preferably, the cosmetic is essence water or essence liquid.

[0028] The beneficial effects of the present invention are:

[0029] The present invention provides a composition with anti-wrinkle efficacy, which synergistically enhances the anti-wrinkle effect of the composition by combining functional factors containing multiple plant extracts with a Spirulina maxima extract and a Fagus sylvatica bud solution. DETAILED DESCRIPTION

[0030] In the description of the present invention, it should be noted that, if the specific conditions are not specified in the examples, the experiments were carried out according to conventional conditions or the conditions recommended by the manufacturer. The reagents or instruments used, if the manufacturer is not specified, are all conventional products that can be purchased commercially.

[0031] Product information:

[0032] Functional factors: provided by Jiangxi Nanwushan Traditional Chinese Medicine Technology Co., Ltd. (trade name: muscle age rhythm factor F5), which is prepared by mixing water, butylene glycol, thyme extract, milo leaf extract, roselle flower extract, honeysuckle flower extract, black ganoderma extract, 1,2-hexanediol, and ethylhexylglycerin in a mass ratio of 59.9:30:1:2:2:2:2:1:0.1;

[0033] Spirulina maxima extract: provided by Guangdong Gexin Biotechnology Co., Ltd.;

[0034] Fagus sylvatica bud solution: provided by Gattefossé (Shanghai) Trading Co., Ltd., prepared by mixing water, Fagus sylvatica bud extract, and phenoxyethanol in a mass ratio of 83:15:2;

[0035] Resveratrol solution: provided by Morechem Co., Ltd., wherein the mass fraction of resveratrol in the solution is 4%;

[0036] Arginine / lysine polypeptide solution: provided by Activen SA, with the trade name XEP-018, wherein the mass fraction of arginine / lysine polypeptide in the solution is 0.0024%.

[0037] Unless otherwise specified, the preparation method of the anti-wrinkle composition in the following examples and comparative examples is as follows: functional factors, Spirulina maxima extract, Fagus sylvatica bud solution and resveratrol solution are mixed at 85° C. for 5 minutes to obtain the anti-wrinkle composition.

[0038] Examples 1-4

[0039] An anti-wrinkle composition, the raw material mass ratio in its formula is shown in Table 1:

[0040] Table 1

[0041]

[0042] Comparative Examples 1-11

[0043] An anti-wrinkle composition, the weight ratios of the raw materials in the formula are shown in Table 2:

[0044] Table 2

[0045] Group Functional Factor Spirulina Maxima Extract Fagus sylvatica bud solution Other Ingredients Comparative Example 1 0 1.0 0.05 0 Comparative Example 2 6 0 0.05 0 Comparative Example 3 6 1.0 0 0 Comparative Example 4 0 1.0 0.05 6 Comparative Example 5 0 1.0 0.05 6 Comparative Example 6 0 1.0 0.05 6 Comparative Example 7 0 1.0 0.05 6 Comparative Example 8 0 1.0 0.05 6 Comparative Example 9 6 0 0.05 1.0 Comparative Example 10 6 1.0 0 0.05 Comparative Example 11 6 1.0 0 0.05

[0046] It should be noted that:

[0047] The other ingredients in Comparative Examples 4-8 are functional factors prepared by mixing water, butylene glycol, plant extract, 1,2-hexanediol, and ethylhexylglycerin in a mass ratio of 59.9:30:9:1:0.1, and the plant extracts in the functional factors of Comparative Examples 4-8 are thyme extract, mirabilis leaf extract, roselle flower extract, honeysuckle flower extract, and black ganoderma lucidum extract, respectively;

[0048] The other ingredients in Comparative Example 9 are commercially available Spirulina platensis extract;

[0049] The other ingredients in Comparative Example 10 are commercially available astragalus extract;

[0050] The other component in Comparative Example 11 is resveratrol solution.

[0051] Application Example 1

[0052] A cosmetic, calculated by mass fraction, has a formula as shown in Table 3:

[0053] Table 3

[0054] Group Anti-wrinkle composition Skin Conditioners Moisturizer Emulsifier Antioxidants Thickener water Application Example 1 7% 1.3% 10% 0.5% 0.5% 0.1% To100%

[0055] It should be noted that:

[0056] The preparation method of the cosmetics is as follows: the anti-wrinkle composition prepared in Example 1, a skin conditioner, a moisturizer, an emulsifier, an antioxidant, and a thickener are mixed, heated to 85° C. for homogenization for 5 minutes, and then cooled to 30° C. to obtain the cosmetics;

[0057] In Application Example 1, the skin conditioning agent is an arginine / lysine polypeptide solution;

[0058] In Application Example 1, the moisturizing agent is composed of butylene glycol, glycerol, and trehalose, and the mass ratio of butylene glycol, glycerol, and trehalose is 4:1:0.5;

[0059] In Application Example 1, the emulsifier is polysorbate-20;

[0060] In Application Example 1, the antioxidant is p-hydroxyacetophenone;

[0061] In Application Example 1, the thickener is carbomer.

[0062] Application Example 2

[0063] It is basically the same as Application Example 1, except that the cosmetic does not contain a skin conditioning agent.

[0064] Application Example 3

[0065] The method is basically the same as Application Example 1, except that the cosmetic does not contain a moisturizer.

[0066] Application Example 4

[0067] The method is basically the same as Application Example 1, except that the cosmetic does not contain an antioxidant.

[0068] Performance Testing:

[0069] 1.DPPH free radical scavenging rate test

[0070] Excessive production of DPPH free radicals can lead to natural aging and photoaging of the skin, resulting in wrinkles. Therefore, whether it has the ability to scavenge free radicals is one of the important indicators for evaluating anti-aging and anti-oxidation cosmetics (raw materials).

[0071] This test refers to the laboratory method (HMC-WI-030 DPPH free radical scavenging rate) and compares the DPPH free radical scavenging rate test results of the test sample with that of the negative control. If the scavenging rate of the test sample is higher than that of the negative control and there is a significant difference (P<0.05), it can be considered that the test sample has a certain antioxidant effect.

[0072] 1.1 Instruments and Equipment

[0073] BSA224S analytical balance, L6s UV spectrophotometer

[0074] 1.2 Reagents

[0075] DPPH (1,1-diphenyl-2-picrylhydrazyl), 98%

[0076] 1.3 Test methods

[0077] (1) Treatment of control and test samples

[0078] Sample group: the compositions prepared in Examples 1-4 and Comparative Examples 1-11 were diluted with pure water to a solution having a mass fraction of 7% of the composition, and the cosmetics prepared in Application Examples 1-4;

[0079] Negative control: pure water.

[0080] (2) Test operation steps

[0081] Set up a sample group and a negative control group. Set up 3 parallel tubes for each group. Add the corresponding reagent solution to each group, shake gently, and let stand at room temperature for 5 minutes. Transfer the reaction solution of each group into a 1 cm cuvette and measure the absorbance at 517 nm.

[0082] (3) The calculation formula is shown in Formula 1:

[0083]

[0084] Where: T—absorbance of sample tube, i.e. absorbance of solution after sample reacts with DPPH;

[0085] T0—sample background absorbance;

[0086] C—the average value of the absorbance of the DPPH tube three times, that is, the absorbance of the DPPH solution when no sample is added;

[0087] C0—Solvent background absorbance.

[0088] (4) Data analysis

[0089] The statistical analysis software was SPSS, and the comparison between the DPPH free radical scavenging rate of the test sample and the negative control was performed using an independent sample t-test. The above statistical analyses were all two-tailed tests, and the significance level was α = 0.05. P>0.05 indicated that there was no significant difference between the two groups; P<0.05 indicated that there was a significant difference between the two groups.

[0090] The test results are shown in Table 4:

[0091] Table 4

[0092]

[0093] Conclusion analysis:

[0094] 1. It can be seen from Examples 1-3 that when the mass ratio of the functional factor, Spirulina maxima extract, and Fagus sylvatica bud solution in the anti-wrinkle composition is changed, the scavenging rate of free radicals is also different, and the ratio in Application Example 1 is the best;

[0095] Observing Example 1 and Example 4 again, when resveratrol solution is further added to the anti-wrinkle composition, since resveratrol can directly react with free radicals, reduce the activity of free radicals, and prevent further chain reactions of free radicals, the scavenging rate of free radicals can be further improved;

[0096] Further observation of Example 1, Example 4 and Comparative Example 11 shows that when the added amounts of the functional factors and Spirulina maxima extract in the anti-wrinkle composition remain unchanged, the Fagus sylvatica bud solution and the resveratrol solution are mixed in equal proportions and added to the anti-wrinkle composition, the free radical scavenging rate should be 41.288% ((free radical scavenging rate of Example 1 + free radical scavenging rate of Comparative Example 11) / 2), while that of Example 4 reaches 42.863%. It can be seen that there is a synergistic effect between the resveratrol solution and the functional factors, Spirulina maxima extract and Fagus sylvatica bud solution.

[0097] 2. It can be seen from Example 1 and Comparative Examples 1-3 that when the anti-wrinkle composition lacks functional factors, Spirulina maxima extract or Fagus sylvatica bud solution, the free radical scavenging rate will be greatly reduced, among which the cosmetics made without functional factors have the largest reduction, reaching 22.731%;

[0098] Further combined with the data in Table 4, it can be seen that the free radical scavenging rate of the anti-wrinkle composition formed by the functional factor, Spirulina maxima extract and Fagus sylvatica bud solution should be 35.979% ((free radical scavenging rate of comparative example 1 + free radical scavenging rate of comparative example 2 + free radical scavenging rate of comparative example 3) / 2), while the free radical scavenging rate of the anti-wrinkle composition prepared in Example 1 reached 40.922%. It can be seen that the functional factor, Spirulina maxima extract and Fagus sylvatica bud solution have a synergistic effect, which further improves the free radical scavenging rate of the anti-wrinkle composition.

[0099] 3. It can be seen from Example 1 and Comparative Examples 4-8 that when the functional factor in the anti-wrinkle composition contains only one plant extract, its free radical scavenging rate is also greatly reduced compared with Example 1;

[0100] Further observation of comparative examples 4-8 shows that when the functional factors contain five plant extracts, namely, thyme extract, iris leaf extract, roselle flower extract, honeysuckle flower extract, and black ganoderma lucidum extract, the free radical scavenging rate of the anti-wrinkle composition formed should be between 28.933% and 30.871%, while Example 1 reached 40.922%. It can be seen that the five plant extracts, namely, thyme extract, iris leaf extract, roselle flower extract, honeysuckle flower extract, and black ganoderma lucidum extract in the functional factors can produce a synergistic effect, further improving the scavenging rate of DPPH free radicals.

[0101] 4. It can be seen from Example 1 and Comparative Example 9 that when the commercially available Spirulina platensis extract is used to replace the Spirulina maxima extract in the anti-wrinkle composition, the scavenging rates of the two for DPPH free radicals are different. It is speculated that the types and contents of the components between the two are different, so the effect after being combined with the functional factor and the European Fagus sylvatica bud solution is worse than that of Application Example 1;

[0102] Similarly, it can be seen from Example 1 and Comparative Example 10 that when the Fagus sibiricum bud solution in the anti-wrinkle composition is replaced with the commercially available Astragalus extract that can also help protein synthesis and smooth wrinkles, the effect achieved by Comparative Example 10 is also poor;

[0103] It can be seen from this that the Spirulina maxima extract and Fagus sylvatica bud solution in the anti-wrinkle composition are irreplaceable.

[0104] 5. It can be seen from Example 1 and Application Example 1 that when the skin conditioner, moisturizer, and antioxidant are simultaneously added to the anti-wrinkle composition to prepare a cosmetic, Application Example 1 also has a significantly improved free radical scavenging rate compared to Example 1;

[0105] Further observation of Application Examples 1-4 shows that when the cosmetics lack skin conditioners, moisturizers, and antioxidants, respectively, it will also affect the free radical scavenging rate of the cosmetics for DPPH.

[0106] 2. Elastase inhibition test

[0107] Elastase is mainly synthesized and secreted by fibroblasts, which can degrade elastin in the skin and cause skin aging. The experimental principle of inhibiting elastase is that porcine pancreatic elastase catalyzes the reaction with the enzyme substrate. After adding the active substance, the absorbance changes. The magnitude of the absorbance change reflects the inhibition rate of the elastase inhibitor.

[0108] This test refers to the laboratory method (HMC-WI-028 elastase inhibition rate) and compares the elastase inhibition rate test results of the test sample with that of the negative control. If the inhibition rate of the test sample is higher than that of the negative control and there is a significant difference (P<0.05), it can be considered that the test sample has a certain firming effect.

[0109] 2.1 Instruments and Equipment

[0110] BSA224S analytical balance, RT-6100 ELISA analyzer;

[0111] 2.2 Reagents

[0112] Elastase (porcine pancreas), BR, N-succinyl-L-alanyl-L-alanyl-L-alanine, 98%;

[0113] 2.3 Test methods

[0114] (1) Treatment of control and test samples

[0115] Sample group: the compositions prepared in Examples 1-4 and Comparative Examples 1-11 were diluted with pure water to a solution having a composition mass fraction of 7%, and the cosmetics prepared in Application Examples 1-4;

[0116] Negative control: pure water.

[0117] (2) Test operation steps

[0118] Set up a sample group and a negative control group, and set up 3 parallels for each group. Add the corresponding reagent solution into a 96-well plate, shake it gently, incubate it at 25°C for 15 minutes, place it in an enzyme reader, and measure the absorbance at 410nm.

[0119] (3) The calculation formula is shown in Formula 2:

[0120]

[0121] Where: A—is the absorbance of the reaction solution without sample;

[0122] B—is the absorbance of the reaction solution without sample and enzyme;

[0123] C—is the absorbance of the reaction solution containing sample and enzyme;

[0124] D—is the absorbance of the reaction solution containing sample and without enzyme.

[0125] (4) Data analysis

[0126] The statistical analysis software was SPSS, and the comparison between the elastase inhibition rate of the test sample and the negative control was performed using the independent sample t test. The above statistical analyses were all two-tailed tests, and the significance level was α = 0.05. P>0.05 indicated that there was no significant difference between the two groups; P<0.05 indicated that there was a significant difference between the two groups.

[0127] The test results are shown in Table 5:

[0128] Table 5

[0129]

[0130]

[0131] Conclusion analysis:

[0132] 1. It can be seen from Examples 1-3 that when the mass ratio of the functional factor, Spirulina maxima extract, and Fagus sylvatica bud solution in the anti-wrinkle composition is changed, the inhibition rate of elastin is also different, and the ratio in Example 1 is the best;

[0133] Observing Example 1 and Example 4 again, when resveratrol solution is further added to the anti-wrinkle composition, since resveratrol can directly react with free radicals, reduce the activity of free radicals, and prevent further chain reactions of free radicals, the inhibition rate of elastin can be further improved;

[0134] Further observation of Example 1, Example 4 and Comparative Example 11 shows that when the added amounts of the functional factors and Spirulina maxima extract in the anti-wrinkle composition remain unchanged, the Fagus sylvatica bud solution and the resveratrol solution are mixed in equal proportions and added to the anti-wrinkle composition, the inhibition rate of elastase should be 42.596% ((free radical scavenging rate of Example 1 + free radical scavenging rate of Comparative Example 11) / 2), while that of Example 4 reaches 44.782%. It can be seen that there is a synergistic effect between the resveratrol solution and the functional factors, Spirulina maxima extract and Fagus sylvatica bud solution.

[0135] 2. It can be seen from Example 1 and Comparative Examples 1-3 that when the anti-wrinkle composition lacks functional factors, Spirulina maxima extract or Fagus sylvatica bud solution, the inhibition rate of the anti-wrinkle composition on elastase will be greatly reduced, among which the cosmetics made without functional factors have the largest reduction, reaching 23.038%;

[0136] Further combined with the data in Table 5, it can be seen that the anti-wrinkle composition formed by the functional factor, Spirulina maxima extract and Fagus sylvatica bud solution should have an inhibition rate of 35.344% for elastase ((elastase inhibition rate of comparison example 1 + elastase inhibition rate of comparison example 2 + elastase inhibition rate of comparison example 3) / 2), and the anti-wrinkle composition prepared in Example 1 has a free radical scavenging rate of 42.365%. It can be seen that the functional factor, Spirulina maxima extract and Fagus sylvatica bud solution have a synergistic effect, which further improves the inhibition rate of the anti-wrinkle composition for elastase.

[0137] 3. It can be seen from Example 1 and Comparative Examples 4-8 that when the functional factor in the anti-wrinkle composition contains only one plant extract, the inhibition rate of elastase is also greatly reduced compared with Example 1;

[0138] Further observation of comparative examples 4-8 shows that when the functional factors contain five plant extracts, namely, thyme extract, iris leaf extract, roselle flower extract, honeysuckle flower extract, and black ganoderma lucidum extract, the elastase inhibition rate of the anti-wrinkle composition formed should be between 27.689% and 30.565%, while Example 1 reached 42.365%. It can be seen that the five plant extracts, namely, thyme extract, iris leaf extract, roselle flower extract, honeysuckle flower extract, and black ganoderma lucidum extract in the functional factors can produce a synergistic effect, further improving the inhibition rate of cosmetics against elastase.

[0139] 4. It can be seen from Example 1 and Comparative Example 9 that when the commercially available Spirulina platensis extract is used to replace the Spirulina maxima extract in the anti-wrinkle composition, the inhibition rate of the cosmetics prepared from the two on elastase is different. It is speculated that the types and contents of the ingredients between the two are different, so the effect after being combined with the functional factor and the European Fagus sylvatica bud solution is worse than that of Application Example 1;

[0140] Similarly, by observing Example 1 and Comparative Example 10, it can be seen that when the Fagus sibiricum bud solution in the anti-wrinkle composition is replaced with the commercially available Astragalus extract that can also help protein synthesis and smooth wrinkles, the effect obtained in Application Example 14 is also poor;

[0141] It can be seen from this that the Spirulina maxima extract and Fagus sylvatica bud solution in the anti-wrinkle composition are irreplaceable.

[0142] 5. It can be seen from Example 1 and Application Example 1 that when the skin conditioner, moisturizer, and antioxidant are simultaneously added to the anti-wrinkle composition to prepare a cosmetic, compared with Example 1, Application Example 1 also has a significantly improved inhibition rate for elastase;

[0143] Further observation of Application Examples 1-4 shows that when the cosmetics lack skin conditioners, moisturizers, and antioxidants, respectively, it will also affect the inhibition rate of the cosmetics on elastase.

[0144] The above embodiments are preferred implementation modes of the present invention, but the implementation modes of the present invention are not limited to the above embodiments. Any other changes, modifications, substitutions, combinations, and simplifications made without departing from the spirit and principles of the present invention shall be equivalent replacement methods and shall be included in the protection scope of the present invention.

Claims

1. An anti-wrinkle composition, characterized in that: The composition contains functional factors, spirulina maxima extract, and European Fagus sylvatica bud solution, and the mass ratio of the functional factors, spirulina maxima extract, and European Fagus sylvatica bud solution is 5-7: 0.5-1.5: 0.01-0.1; The functional factor is prepared by mixing water, butylene glycol, thyme extract, mirabilis leaf extract, roselle flower extract, honeysuckle flower extract, black ganoderma extract, 1,2-hexanediol and ethylhexylglycerin in a mass ratio of 55-60:28-32:1:1-3:1-3:1-3:1-3:0.8-1.2:0.

1.

2. The anti-wrinkle composition according to claim 1, characterized in that The composition also contains a resveratrol solution, and the mass ratio of the resveratrol solution to the Fagus sylvatica bud solution is 0.001-0.1:0.01-0.

1.

3. Use of the anti-wrinkle composition according to any one of claims 1 to 2 in the preparation of cosmetics.

4. A cosmetic, characterized in that: The cosmetic contains 1 to 30 wt % of the anti-wrinkle composition according to any one of claims 1 to 2.

5. The cosmetic according to claim 4, characterized in that: The cosmetics also contain a skin conditioner, a moisturizer, an emulsifier, an antioxidant, and a thickener, and the mass ratio of the skin conditioner, the moisturizer, the emulsifier, the antioxidant, and the thickener is 1-1.5:9-11:0.4-0.6:0.4-0.6:0.05-0.

15.

6. The cosmetic according to claim 5, characterized in that: The skin conditioning agent is selected from at least one of niacinamide, arginine / lysine polypeptide solution, and ergothioneine; The moisturizing agent is selected from at least one of butylene glycol, methyl gluceth-20, glycerin, dipropylene glycol, trehalose, 1,2-hexanediol, and sodium hyaluronate; The emulsifier is selected from at least one of polysorbate-20 and PEG-40 hydrogenated castor oil; The antioxidant is p-hydroxyacetophenone; The thickener is selected from at least one of carbomer, acrylic acid (esters) / C10-30 alkyl acrylate cross-linked polymer and xanthan gum.

7. The cosmetic according to claim 4, characterized in that: The cosmetic is essence water or essence liquid.

Citation Information

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