Radiation device

Abstract

The embodiment of the invention provides a radiation device. The radiation device comprises a rotatable assembly which can rotate around a rotation axis; the beam assembly is arranged on the rotatable assembly, the beam assembly comprises a plurality of beam modules, each beam module is used for emitting a radiation beam, and the plurality of beam modules are arranged at intervals along the circumferential direction of the rotatable assembly; and the power divider is arranged on the rotatable assembly, the power divider is provided with a plurality of power distribution ports, the plurality of power distribution ports are respectively connected with the plurality of beam modules, and the beam modules and the power divider can rotate around the rotation axis along with the rotatable assembly.

Description

Technical Field

[0001] The present disclosure relates to the fields of radiation inspection and radiation therapy, in particular to the field of flash therapy, and more particularly to a radiation device. Background Art

[0002] Ultra-high dose rate includes a dose rate of more than 40Gy / s in a short period of time, such as an average dose rate of more than 300Gy / s, which can be applied to medical radiotherapy, container security inspection, industrial imaging and other fields. Take flash therapy as an example, which is also called ultra-high dose rate radiotherapy (abbreviated as: FLASH-RT), a treatment option for tumor radiotherapy. The use of flash therapy technology not only kills tumor cells, but also has lower toxic side effects on normal tissues, and reduces the risk of damage to the patient's body by taking a large amount of rejection drugs after surgery, while shortening the postoperative recovery period and improving the quality of life after surgery.

[0003] In the process of realizing the concept of the present invention, the inventors found that for a radiation device to achieve an ultra-high dose rate, it is necessary to achieve multi-angle ultra-high dose rate radiation at a designated position in a short period of time. How to design the structure of such a radiation device is a problem that researchers in this technical field are currently working on. Summary of the invention

[0004] To solve at least one aspect of the above problems, an embodiment of the present disclosure provides a radiation device.

[0005] In one aspect, a radiation device is provided, comprising: a rotatable component, which is capable of rotating around a rotation axis; a beam assembly arranged on the rotatable component, wherein the beam assembly includes a plurality of beam modules, each of the beam modules is used to emit a radiation beam, and the plurality of beam modules are arranged at intervals along the circumferential direction of the rotatable component; a power divider arranged on the rotatable component, wherein the power divider is provided with a plurality of power distribution ports, and the plurality of power distribution ports are respectively connected to the plurality of beam modules, wherein the beam assembly and the power divider are capable of rotating around the rotation axis along with the rotatable component.

[0006] According to some exemplary embodiments, an output end of each of the beam modules faces a rotation axis of the rotatable component, and the radiation beam output by each of the beam modules converges on the rotation axis.

[0007] According to some exemplary embodiments, the radiation device also includes a pulse transformer disposed on the rotatable component, the pulse transformer being used to convert a DC power supply of a first voltage into a pulse power supply of a second voltage, wherein the second voltage is higher than the first voltage, and the pulse transformer can rotate around the rotation axis with the rotatable component.

[0008] According to some exemplary embodiments, the radiation device also includes a power source disposed on the rotatable component, the power source is connected to the pulse transformer, the power source is used to generate microwave energy, and the power source can rotate around the rotation axis with the rotatable component.

[0009] According to some exemplary embodiments, the radiation device also includes a power synthesizer disposed on the rotatable component, the power synthesizer is connected to the power source, the power synthesizer is used to synthesize the microwave energy provided by the power source, and the power synthesizer can rotate around the rotation axis with the rotatable component.

[0010] According to some exemplary embodiments, the radiation device further includes a plurality of waveguides, the plurality of power distribution ports are respectively connected to the plurality of beam modules through the plurality of waveguides, and waveguide lengths of at least two of the plurality of waveguides are unequal.

[0011] According to some exemplary embodiments, the rotatable component includes a first end and a second end relatively arranged along the extension direction of the rotation axis; the radiation device also includes a mounting plate, which is arranged on the outer wall of the second end of the rotatable component and extends outward along the radial direction of the rotatable component; and the beam assembly is arranged on the mounting plate.

[0012] According to some exemplary embodiments, the mounting plate includes: a first mounting plate, disposed on a first side of the second end; and a second mounting plate, disposed on a second side of the second end opposite to the first side, and a portion of the plurality of beam modules is disposed on the first mounting plate, and another portion of the plurality of beam modules is disposed on the second mounting plate.

[0013] According to some exemplary embodiments, one side surface of the first mounting plate and the second mounting plate are coplanarly arranged to form a second mounting surface, and the plurality of beam modules are arranged on the second mounting surface.

[0014] According to some exemplary embodiments, a plurality of mounting holes are respectively disposed on the first mounting plate and the second mounting plate, and the plurality of mounting holes are used to respectively mount the plurality of beam modules and position the plurality of beam modules on the mounting plates along a circumferential direction.

[0015] According to some exemplary embodiments, the radiation device further comprises a driving component, wherein the driving component is configured to drive the rotatable component to rotate around the rotation axis.

[0016] According to some exemplary embodiments, the rotatable component includes a roller; the driving component includes: a ring gear coaxially arranged on the outer wall of the first end of the roller; and a driving part, which is drivingly connected to the ring gear and is suitable for outputting torque to the ring gear.

[0017] According to some exemplary embodiments, at least one of the beam modules includes an electron linear accelerator.

[0018] According to some exemplary embodiments, the radiation device further includes an adjustment component for adjusting a position of the pulse transformer relative to the power distributor and maintaining the pulse transformer at a preset position. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 is a perspective view of a radiation device according to some exemplary embodiments of the present disclosure;

[0020] Figure 2 yes Figure 1 The schematic structural diagram of the radiation device shown is viewed from a front angle;

[0021] Figure 3 yes Figure 1 The simplified structural schematic diagram of the radiation device shown is viewed from a front angle;

[0022] Figure 4 is a hardware block diagram of a radiation device according to some exemplary embodiments of the present disclosure;

[0023] Figure 5 is a perspective view of a carrier and an adjustment assembly portion according to some exemplary embodiments of the present disclosure;

[0024] Figure 6 yes Figure 5 A schematic diagram of a top view of an adjustment assembly of the exemplary embodiment shown;

[0025] Figure 7 yes Figure 1 A perspective view of the frame of the exemplary embodiment shown, showing the support assembly and the rotatable assembly;

[0026] Figure 8 The structure diagram of the calibration target assembly according to an embodiment of the present disclosure is schematically shown, wherein: Figure 8 (a) is the main view of the calibration target assembly. Figure 8 (b) is a side view of the calibration target assembly;

[0027] Fig. 9 Schematically showing a cross-sectional view of the structure of a rotatable assembly and a calibration target assembly according to an embodiment of the present disclosure;

[0028] Fig.10 A schematic top view of the structure of a rotatable assembly and a calibration target assembly according to an embodiment of the present disclosure is shown;

[0029] Fig.11 Schematically shows an installation zero position state diagram according to an embodiment of the present disclosure; and

[0030] Fig.12 The flowchart of the calibration method according to the embodiment of the present disclosure is schematically shown. DETAILED DESCRIPTION

[0031] In order to make the objectives, technical solutions and advantages of the present disclosure more clearly understood, the present disclosure is further described in detail below in combination with specific embodiments and with reference to the accompanying drawings.

[0032] The terms used herein are only for describing specific embodiments and are not intended to limit the present disclosure. The terms "comprise", "include", etc. used herein indicate the existence of the features, steps, operations and / or components, but do not exclude the existence or addition of one or more other features, steps, operations or components.

[0033] All terms used herein, including technical and scientific terms, have the meanings commonly understood by those skilled in the art, unless otherwise defined. It should be noted that the terms used herein should be interpreted as having a meaning consistent with the context of this specification, and should not be interpreted in an idealized or overly rigid manner.

[0034] When using expressions such as "at least one of A, B, and C, etc.", it should generally be interpreted as the meaning of the expression generally understood by those skilled in the art. For example, "a system having at least one of A, B, and C" should include but not be limited to a system having A alone, B alone, C alone, A and B, A and C, B and C, and / or A, B, C, etc. When using expressions such as "at least one of A, B, or C, etc.", it should generally be interpreted as the meaning of the expression generally understood by those skilled in the art. For example, "a system having at least one of A, B, or C" should include but not be limited to a system having A alone, B alone, C alone, A and B, A and C, B and C, and / or A, B, C, etc.

[0035] Figure 1 is a perspective view of a radiation device according to some exemplary embodiments of the present disclosure. Figure 2 yes Figure 1 The structure schematic diagram of the radiation device shown is observed from the front perspective. Figure 3 yes Figure 1 The illustrated schematic diagram is a simplified structural view of the radiation device as viewed from the front. Figure 4is a hardware block diagram of a radiation device according to some exemplary embodiments of the present disclosure.

[0036] Combined with reference Figure 1 , Figure 2 , Figure 3 and Figure 4 The radiation device 100 provided in the embodiment of the present disclosure includes a frame 1, a pulse transformer 2, a beam assembly 3, a power source 5, a power synthesizer 6, a power divider 7 and a waveguide 8.

[0037] For example, the radiation device 100 provided in the embodiment of the present disclosure may include an ultra-high dose rate radiation device, which is used to generate a radiation beam that can be used in fields such as flash radiotherapy, container security inspection and industrial imaging, and can achieve ultra-high dose rate (for example, above 40Gy / s) radiation transfer, thereby completing the desired radiation in a very short time.

[0038] It should be noted that, in this article, unless otherwise specified, the expression "ultra-high dose rate" includes a dose rate of 40 Gy / s or more in a short period of time, for example, an average dose rate of 300 Gy / s or more. Ultra-high dose rate can be applied to medical radiotherapy, container security inspection, industrial imaging and other fields.

[0039] Take flash therapy as an example, which is also called ultra-high dose rate radiotherapy (FLASH-RT for short), and is a treatment option for tumor radiotherapy. The use of flash therapy technology not only kills tumor cells, but also has low toxic side effects on normal tissues, and reduces the risk of damage to the patient's body by taking a large amount of rejection drugs after surgery, while shortening the postoperative recovery period and improving the quality of life after surgery. In other words, FLASH-RT uses ultra-fast irradiation, and the dose rate is several orders of magnitude higher than the dose rate used in traditional radiotherapy (for example, 20-100Gy / s compared to 1-4Gy / min). Ultra-high dose rates can reduce the toxicity of normal tissues directly induced by radiation, while maintaining the same effective response to lesion tissues. This is the so-called "flash effect."

[0040] For example, the frame 1 may include a support assembly 13, a rotatable assembly 11, and a carrier frame 14. For example, the rotatable assembly 11 may include a roller, and the roller may be configured as a horizontal structure. Figure 1 As shown, the rotatable component 11 has a rotation axis AX1 extending in its axial direction, for example, Figure 1 In the orientation shown, the axial direction of the rotatable component 11 is along the x-direction, and the rotation axis AX1 may be a straight line along the x-direction that passes through the geometric center of the end surface of the rotatable component 11. In the axial direction of the rotatable component 11, the rotatable component 11 has a first end 111 and a second end 112. The rotatable component 11 can rotate around its rotation axis AX1.

[0041] The pulse transformer 2, the beam assembly 3, the power source 5, the power synthesizer 6, the power divider 7 and the waveguide 8 may be arranged on the rotatable component 11. When the rotatable component 11 rotates around its rotation axis AX1, the pulse transformer 2, the beam assembly 3, the power source 5, the power synthesizer 6, the power divider 7 and the waveguide 8 may rotate along with the rotation of the rotatable component 11.

[0042] In the embodiment of the present disclosure, the pulse transformer 2 is used to convert the low-voltage DC power supply into a high-voltage pulse power supply and provide it to the power source 5. The power source 5 is used to generate microwave energy to provide an energy source for the operation of the radiation device. The power synthesizer 6 is used to synthesize the microwave energy provided by the power source 5 to increase the microwave power. The power distributor 7 is used to distribute the microwave energy to the beam assembly 3.

[0043] For example, the pulse transformer 2 may include a primary winding, a secondary winding and a magnetic core. Based on the law of electromagnetic induction, when a low-voltage DC power supply is applied to the primary winding, the current in the primary winding is rapidly changed through the control circuit, thereby generating a changing magnetic field in the magnetic core. This changing magnetic field will induce a high-voltage pulse signal in the secondary winding, realizing the conversion from low-voltage DC to high-voltage pulse. The pulse transformer 2 provides the required high-voltage pulse power supply for the power source 5. By converting the low-voltage DC power supply into a high-voltage pulse power supply, the specific voltage requirements of the power source to generate microwave energy can be met. This conversion method is efficient and stable, and can accurately control the parameters such as the amplitude, width and frequency of the output pulse, providing stable and compliant power support for subsequent microwave energy generation.

[0044] For example, the power source 5 may include a magnetron power source or a klystron power source. The magnetron power source uses the movement of electrons in the magnetic field and the electric field to generate microwave oscillations in the resonant cavity, thereby outputting microwave energy. The klystron power source achieves velocity modulation and clustering of the electron beam through the interaction of the electron beam in the input cavity, the drift tube, and the output cavity, thereby generating high-power microwave output. The main function of the power source 5 is to generate microwave energy, provide energy support for the processes such as the acceleration of the electron beam or the ray beam in the beam assembly 3, and is the core generating unit of the microwave energy in the whole system. The performance parameters of the power source 5 may include output power, frequency, efficiency, stability, etc. The output power determines the amount of energy that can be provided for beam acceleration, and the frequency affects the effect and characteristics of the interaction between microwaves and beams. High efficiency means that energy loss can be reduced in the process of converting electrical energy into microwave energy, and stability ensures that the microwave energy output during long-term operation can be maintained within a certain accuracy range, providing a guarantee for the stable operation of the system.

[0045] For example, the power synthesizer 6 is based on the power synthesis technology in the microwave circuit, and can include power synthesizers in the form of transmission line transformer synthesis, waveguide synthesis, etc. Taking the transmission line transformer synthesis as an example, it uses the characteristics of the transmission line to synthesize the microwave signals provided by multiple power sources 5 in a preset circuit structure. By reasonably designing the parameters such as the length and characteristic impedance of the transmission line, the microwave signals of each input are superimposed in phase at the synthesis point, thereby realizing power synthesis. In waveguide synthesis, the microwave energy in different waveguides is synthesized by using the mode characteristics and coupling structure of the waveguide, so that they form a microwave signal with higher power at the output end. The power synthesizer 6 is used to synthesize the microwave energy provided by multiple power sources 5 to increase the microwave power and meet the demand of the beam component 3 for high-power microwaves. Through the power synthesizer 6, multiple relatively low-power microwave sources can be combined to form a high-power microwave source, which not only improves the overall power output of the system, but also has certain flexibility and reliability. For example, when a power source fails, other power sources can still provide part of the power to the system through the power synthesizer to ensure the basic operation of the system and improve the fault tolerance of the system.

[0046] For example, the power distributor 7 can adopt a microwave circuit design with a tree structure or a branch structure. In the power distributor 7, based on the transmission and distribution characteristics of microwave signals, by setting multiple branch ports on the main transmission line and designing the position, length and impedance matching parameters of the branches, the input microwave energy can be distributed to each branch port in a certain proportion, that is, distributed to different beam modules in the beam assembly 3. For example, in a T-type power distributor, the microwave signal in the main transmission line will be divided into two branches at the T-type node. By adjusting the length and characteristic impedance of the branch line, the microwave energy can be evenly distributed or distributed to the two branches in a specific proportion. The power distributor 7 is used to distribute the microwave energy synthesized by the power synthesizer 6 to each beam module in the beam assembly 3 evenly or according to specific needs, ensuring that each beam module can obtain suitable microwave energy to drive the acceleration of the electron beam or ray beam and other processes.

[0047] In some exemplary embodiments of the present disclosure, the beam assembly 3 may include a plurality of beam modules 30. Exemplarily, the beam assembly 3 may include N beam modules 30, where N is a positive integer greater than or equal to 2, for example, N may be equal to 2, 3, 4, 5, 6, 8, 10, etc. In the illustrated embodiment, N is equal to 5, that is, the beam assembly 3 includes 5 beam modules 30. For the convenience of description, the 5 beam modules 30 may be described as a first beam module 301, a second beam module 302, a third beam module 303, a fourth beam module 304, and a fifth beam module 305, respectively.

[0048] Reference Figure 4, the power distributor 7 may include N power distribution ports. In the illustrated embodiment, the power distributor 7 may include 5 power distribution ports. For ease of description, the 5 power distribution ports may be described as a first power distribution port 71, a second power distribution port 72, a third power distribution port 73, a fourth power distribution port 74, and a fifth power distribution port 75, respectively.

[0049] The waveguide 8 may include N sub-waveguides. In the illustrated embodiment, the waveguide 8 may include 5 sub-waveguides. For ease of description, the 5 sub-waveguides may be described as a first sub-waveguide 81, a second sub-waveguide 82, a third sub-waveguide 83, a fourth sub-waveguide 84, and a fifth sub-waveguide 85, respectively.

[0050] Exemplarily, the first power distribution port 71 can be connected to the first beam module 301 through the first sub-waveguide 81, the second power distribution port 72 can be connected to the second beam module 302 through the second sub-waveguide 82, the third power distribution port 73 can be connected to the third beam module 303 through the third sub-waveguide 83, the fourth power distribution port 74 can be connected to the fourth beam module 304 through the fourth sub-waveguide 84, and the fifth power distribution port 75 can be connected to the fifth beam module 305 through the fifth sub-waveguide 85.

[0051] In some exemplary embodiments, the first sub-waveguide 81, the second sub-waveguide 82, the third sub-waveguide 83, the fourth sub-waveguide 84, and the fifth sub-waveguide 85 may have a predetermined waveguide length, respectively. Exemplarily, the waveguide lengths of at least two of the first sub-waveguide 81, the second sub-waveguide 82, the third sub-waveguide 83, the fourth sub-waveguide 84, and the fifth sub-waveguide 85 are not equal. The waveguide length of each of the first sub-waveguide 81, the second sub-waveguide 82, the third sub-waveguide 83, the fourth sub-waveguide 84, and the fifth sub-waveguide 85 matches the microwave energy distributed by each power distribution port.

[0052] It should be noted that the expressions "first", "second" and the like are only for the convenience of description and are not intended to limit the structure of each beam module. In the embodiments of the present disclosure, the structures of each beam module may be the same or different, and the embodiments of the present disclosure do not impose any particular limitation on this.

[0053] Exemplarily, in some embodiments, the beam module 30 may include an electron linear accelerator, for example, the beam module 30 may include components such as an electron gun, an accelerating tube, a focusing system, a beam monitoring device, a beam transmission line, and a cooling device.

[0054] For example, an electron gun may include a cathode, an anode, and a focusing electrode. The cathode may be made of a thermal electron emission material, such as a tungsten filament or a barium tungsten cathode, which can emit a large number of electrons when heated to a certain temperature. There is a small hole on the anode for electrons to pass through. At the same time, a high voltage is applied between the anode and the cathode to form a strong electric field, so that the electrons emitted by the cathode are accelerated to move toward the anode under the action of the electric field. The focusing electrode is used to focus the electron beam into a more concentrated electron stream. The electron gun is used to generate an initial electron beam and provide an electron source for the entire beam module.

[0055] For example, an accelerating tube may include a series of accelerating cavities that are interconnected by coupling structures. The accelerating cavity may be made of metal material, and a specific electromagnetic field distribution may be formed inside. A high-frequency power input device may be provided on the outside of the accelerating tube to transmit microwave power to the accelerating cavity. In the accelerating tube, the electron beam is accelerated by a microwave electric field. When microwave power is input into the accelerating cavity, an alternating electric field is formed in the accelerating cavity. When the electron beam passes through the accelerating cavity, the electric field will do work on the electrons, causing the electrons to gain energy, thereby achieving acceleration. Through the continuous acceleration of multiple accelerating cavities, the electron beam can obtain higher energy.

[0056] For example, the focusing system may include an electromagnetic lens, which is composed of a coil and an iron core. A certain current is passed through the coil to generate a magnetic field, which exerts a force on the moving electron beam, thereby focusing the electron beam. In an electron linear accelerator, multiple electromagnetic lenses can be arranged at different positions to form a focusing system. Since the electron beam has a natural tendency to diverge during the acceleration and transmission process, the role of the focusing system is to generate an appropriate magnetic field so that the electron beam is subjected to an inward focusing force, thereby maintaining the beam intensity and focusing state of the electron beam, reducing the divergence of the beam, and ensuring that the electron beam can be accurately transmitted to the target position.

[0057] For example, the beam monitoring device may include a beam position monitor, a beam intensity monitor, and a beam energy spectrum monitor. The beam position monitor may use a capacitive or inductive sensor to determine the position of the electron beam by detecting the interaction between the electron beam and the sensor. The beam intensity monitor may be a Faraday cup or other type of current sensor, which is used to measure the current of the electron beam to obtain the beam intensity. The beam energy spectrum monitor may use a magnetic field or an electric field to deflect the electron beam, and then measure the distribution of electrons of different energies through a detector. Through the beam monitoring device, various parameters of the electron beam, such as beam position, intensity, and energy distribution, may be monitored in real time.

[0058] For example, a beam transmission line may include a metal pipe and a vacuum system. The metal pipe is used to guide the transmission of the electron beam, and its inner wall has good finish and conductivity to reduce the interaction between the electron beam and the pipe wall and energy loss. The vacuum system includes a vacuum pump, a vacuum valve, a vacuum measuring device, etc. The vacuum pump is used to evacuate the pipe into a high vacuum state to reduce the collision and scattering of the electron beam and gas molecules. The beam transmission line transmits the electron beam generated by the electron linear accelerator to a designated location, such as to a radiation device for subsequent application. At the same time, a high vacuum environment is maintained in the pipe to ensure that the electron beam can be smoothly transmitted under the conditions of low scattering and low energy loss.

[0059] For example, the cooling system may include a cooling circulation pump, cooling pipes, a heat exchanger, and a temperature sensor. The cooling pipes are distributed around the various key components of the electron linear accelerator, such as the electron gun, the accelerating tube, and the focusing system, which generate a large amount of heat during operation. The cooling circulation pump is used to drive the cooling medium to circulate in the pipe. The heat exchanger is used to dissipate the heat absorbed by the cooling medium to the external environment, and the temperature sensor monitors the temperature of the cooling medium and the temperature of each component in real time. The cooling system can cool the various components in the electron linear accelerator to prevent them from being damaged or degraded due to overheating. When the electron linear accelerator is working, the electron gun emits electrons, the microwave power dissipates in the accelerating tube, and the magnetic field generated by the focusing system will generate heat. The cooling system takes away this heat through the circulating cooling medium, keeps the temperature of the components within a reasonable range, ensures the stable operation of the electron linear accelerator and extends the service life of the equipment.

[0060] Reference Figures 1 to 3 In the rotatable component 11, the drum can be configured as a horizontal structure. The first end 111 and the second end 112 of the rotatable component 11 are rotatably disposed on the support component 13. The support frame 14 is disposed on the outer wall of the first end 111, and is suitable for carrying the external pulse transformer 2, so that the pulse transformer 2 rotates synchronously with the rotatable component 11.

[0061] In some exemplary embodiments, the rotatable component 11 is configured as a substantially cylindrical tube structure. To meet the assembly and use requirements of the rotatable component 11 and other components, a suitable through hole and / or groove structure may be formed on the tube structure of the main body, specifically, a through hole suitable for accommodating the passage of the beam of radiation. Further, to meet the assembly and bearing requirements of the rotatable component 11 and other components of the radiation device, an appropriate number of reinforcing ribs may be provided on its inner wall and / or outer wall, and the reinforcing ribs may be arranged along the circumference of the rotatable component 11 or along the axial direction of the rotatable component 11.

[0062] In some exemplary embodiments, the rotatable component 11 is configured as a horizontal structure, that is, the axis of the rotatable component 11 is along the Figure 1 The x direction shown extends and is substantially parallel to the horizontal plane. In this way, when the inspection object is subjected to radiation scanning, the inspection object can be introduced into the inner space of the rotatable component 11 along the horizontal direction.

[0063] In some exemplary embodiments, the support frame 14 is mounted on the outer wall of the rotatable component 11, specifically, it can be mounted on the outer wall surface of the rotatable component 11 and the support frame 14 extends radially outward of the rotatable component 11. Further, the pulse transformer 2 configured by the radiation device is arranged on the support frame 14, so as to be connected to the rotatable component 11 through the support frame 14, and rotate synchronously with the rotatable component 11 during the rotation of the rotatable component 11. The support frame 14 includes but is not limited to being mounted on the outside of the rotatable component 11 by riveting, welding, bolt connection, integral formation and any other means.

[0064] In this embodiment, the rotatable component 11 is rotatably disposed on the support component 13, and is suitable for providing a reliable installation platform for the radiation device, so that the rays output by the multiple beam modules configured by the radiation device can be accurately converged in the rotatable component 11. The support frame is used to assemble components such as the pulse transformer on the rotatable component 11 and move with the rotatable component 11 to position and connect with other components of the radiation device, so that during the operation of the radiation device, the pulse transformer converts the low-voltage DC power supply into a high-voltage pulse power supply, thereby coordinating with the power source to provide the required energy for the accelerating tube in the beam module to generate high-energy rays.

[0065] According to some exemplary embodiments of the present disclosure, Figure 1 and Figure 2 As shown, the rotatable component 11 is also suitable for installing components such as the beam component 3, the power source 5, the power synthesizer 6, and the power distributor 7, so that the beam component 3, the power source 5, the power synthesizer 6, the power distributor 7 and the like rotate synchronously with the rotatable component 11. For example, the beam component 3 is arranged on the outer side of the second end 112 of the rotatable component 11, and the power distributor 7 is arranged on the outer wall of the portion of the rotatable component 11 located between the first end and the second end.

[0066] In some exemplary embodiments, the carrier 14 is disposed on the outer wall of the rotatable component 11 near the first end 111, the beam assembly 3 is disposed at the second end 112 of the rotatable component 11, and the power divider 7 is disposed at the portion of the rotatable component 11 between the first end 111 and the second end 112. In this way, by installing different components or assemblies of the radiation device at different parts of the rotatable component 11, the forces on various parts of the rotatable component 11 can be made more uniform, so as to prevent stress concentration, and more effectively prevent the rotatable component 11 from being overloaded during rotation.

[0067] Figure 5 is a perspective view of a carrier and an adjustment assembly portion according to some exemplary embodiments of the present disclosure.

[0068] According to the embodiments of the present disclosure, Figure 1 and Figure 5 As shown, the support frame 14 includes a mounting portion 141 and a bearing portion 142. The mounting portion 141 is disposed on the outer wall of the rotatable component 11 and extends outwardly along the radial direction of the rotatable component 11. The bearing portion 142 is disposed at one end of the mounting portion 141 away from the rotatable component 11 and forms a first mounting surface parallel to the axis of the rotatable component 11.

[0069] In some exemplary embodiments, such as Figure 5 As shown, two carriers 14 are provided on the rotatable component 11, and the two carriers 14 are symmetrically arranged on both radial sides of the rotatable component 11. Specifically, a pulse transformer 2 is mounted on the first mounting surface formed by each carrier 14. The pulse transformers 2 located on both sides of the axis of the rotatable component 11 are respectively connected to the power distributor nearby.

[0070] For example, two power distributors 7 can be set, one power distributor 7 can be set at the upper part of the rotatable component 11 through a distributor bracket 12, and the other power distributor can be set at the lower part of the rotatable component 11 through another distributor bracket. The two power distributors are respectively connected to the pulse transformer 2 through waveguides.

[0071] In some exemplary embodiments, Figure 1 and Figure 5 As shown, each support frame 14 includes two mounting portions 141, and the two mounting portions 141 are arranged along the x direction on the outer wall of the rotatable component 11. Specifically, a bearing portion 142 is arranged between the lower ends of the two mounting portions 141.

[0072] In some exemplary embodiments, Figure 5 As shown, the mounting portion 141 is configured as a substantially “T”-shaped plate-like structure, the upper end of which is relatively small in width can be directly or indirectly mounted on the outer wall of the rotatable component 11 through other connecting members, and the lower end of which is relatively large in width is used to mount the bearing portion 142. Specifically, the bearing portion 142 includes but is not limited to a substantially rectangular plate-like structure, the two opposite sides of which are mounted on the mounting portion 141 on the same side, as shown in FIG. Figure 5 As shown, the upper surface of the bearing portion 142 forms the above-mentioned first mounting surface to carry the pulse transformer 2. The bearing portion 142 and the mounting portion 141 are connected by, but not limited to, riveting, welding, bolt connection, integral connection and any other method.

[0073] Figure 6 yes Figure 5 A schematic diagram of a top view of an adjustment assembly of an exemplary embodiment is shown.

[0074] In some exemplary embodiments, the pulse transformer 2 is connected to the power divider via a waveguide, so that the output end of the pulse transformer 2 can output a microwave signal to the power divider. The waveguide is suitable for guiding the conduction of the microwave signal to the power divider.

[0075] In some exemplary embodiments, the waveguide includes, but is not limited to, a hollow metal tube configured to have a circular, square, and elliptical cross-section. Since the waveguide is rigid, when the waveguide is used to connect the pulse transformer 2 to the power distributor through the waveguide, there are precise requirements for the relative positions of the pulse transformer 2 and the power distributor. However, when the carrier 14 is assembled with the rotatable component 11, there must be an assembly error that is difficult to overcome, making it difficult to form a precise positioning between the pulse transformer 2 and the power distributor, resulting in the inability to effectively connect the pulse transformer 2 and the power distributor through the waveguide.

[0076] In view of this, refer to Figure 5 and Figure 6 As shown, according to an embodiment of the present disclosure, the rack 1 further includes an adjustment component 16. The adjustment component 16 is disposed between the carrier 14 and the pulse transformer 2, and is suitable for adjusting the position of the pulse transformer 2 relative to the power distributor and maintaining the pulse transformer 2 in the assembled position. In this way, the position of the pulse transformer 2 disposed on the carrier 14 can be adjusted by the adjustment component 16, for example, along the Figure 5 The x-direction and / or y-direction shown is adjusted so that the distance between the pulse transformer 2 and the power distributor is just such that a connection can be made via the waveguide.

[0077] According to the embodiments of the present disclosure, Figure 5 and Figure 6 As shown, the adjustment component 16 is disposed on the bearing portion 142 , and is suitable for making the pulse transformer 2 translate along a direction parallel to the first mounting surface and / or move closer to or away from the rotatable component 11 along a direction orthogonal to the first mounting surface.

[0078] According to the embodiments of the present disclosure, Figure 5 and Figure 6 As shown, the adjustment assembly 16 includes a moving plate 161 and a lifting member 163. The moving plate 161 is slidably disposed on the first mounting surface, and is suitable for translation along the first direction or the second direction. The lifting member 163 is disposed on the moving plate 161 and abuts against the first mounting surface, and is suitable for adjusting the distance between the moving plate 161 and the first mounting surface along the third direction. Among them, the pulse transformer 2 is mounted on the moving plate 161 to move synchronously with the moving plate 161.

[0079] According to the embodiments of the present disclosure, Figure 5 and Figure 6 As shown, the adjustment assembly 16 also includes a limiter, which is suitable for limiting the displacement of the movable plate 161 along the first direction and the second direction, so that the pulse transformer 2 is maintained in the assembly position.

[0080] In some exemplary embodiments, Figure 5 and Figure 6 As shown, the adjustment assembly 16 includes a moving plate 161, and the moving plate 161 is connected to the first mounting surface of the bearing portion 142 of the bearing frame 14 through a second screw 167. Specifically, the moving plate 161 is Figure 5 As shown, mounting beams 162 are integrally provided at both ends in the x direction, and a larger distance between the two mounting beams 162 and the first mounting surface than between the moving plate 161 and the first mounting surface is provided to facilitate the installation of the lifting member 163 .

[0081] In some exemplary embodiments, Figure 5 and Figure 6 As shown, the adjustment assembly 16 includes a plurality of pairs of lifting members 163, and the two lifting members 163 in each pair are symmetrically arranged at the corners of the moving plate 161, that is, a lifting member 163 is arranged at each corner of the moving plate. The lifting member 163 includes an integrally formed screw rod and a ball head.

[0082] For example, the number of the lifting members 163 can be set to 2, 3, 5, 6 or any other number.

[0083] For another example, the lifting member 163 may be disposed in the middle or at other locations of the movable plate 161 .

[0084] In some exemplary embodiments, Figure 5 and Figure 6 As shown, a ball is provided in the ball head of the lifting member 163 for rolling, and the ball is pressed against the first mounting surface. Figure 5 The y direction shown in the figure is extended, and is threadedly matched with the mounting beam 162. In this way, the movable plate 161 can be slidably supported on the first mounting surface of the bearing portion 142 through the lifting member 163, so that the movable plate 161 can be translated relative to the first mounting surface, and the spacing between the movable plate 161 and the first mounting surface can be adjusted.

[0085] In some exemplary embodiments, Figure 5 and Figure 6As shown, the base plate at the bottom of the pulse transformer 2 is fixed to the movable plate 161 by the first screw 166, so as to be integrally connected with the movable plate 161, so as to be translated or lifted with the movable plate 161. With the participation of the above-mentioned lifting member 163, the pulse transformer 2 can adjust the relative position with the first mounting surface to facilitate the precise connection with the waveguide. In addition to the design requirements of realizing position adjustment, corresponding limit members can also be configured to keep the pulse transformer 2 and the power distributor in the assembly position after they are connected, so as to prevent the two from being misaligned during the rotation of the rotatable component 11.

[0086] In some exemplary embodiments, Figure 5 and Figure 6 As shown, the stopper includes a top block 165, a top screw 164 disposed on the top block 165, and a second screw 167. Specifically, the top block 165 is arranged along the Figure 6 The movable plates 161 are arranged in pairs in the x-direction and the y-direction as shown. Furthermore, each top block 165 is connected to a top screw 164 by a thread, and the end of each top screw 164 presses against the edge of the movable plate 161, so that the position of the movable plate 161 relative to the bearing portion 142 is adjusted and locked by the part of the top screw 164 extending relative to the top block 165. Furthermore, the lifting member 163 is connected to the assembly beam 162 by a thread, and under the action of friction, along the Figure 3 Although there is a certain limiting effect in the z direction as shown, there is still a risk of relative movement under the action of the centrifugal force of the rotating component 11. For this reason, in the embodiment of the present disclosure, the movable plate 161 and the bearing part 142 are further fixed by a second screw 167 to maintain their relative spacing.

[0087] Figure 7 yes Figure 1 A perspective view of a frame of an exemplary embodiment is shown, illustrating a support assembly and a rotatable assembly.

[0088] According to an embodiment of the present disclosure, the frame further includes a mounting plate 15, which is disposed on the outer wall of the second end of the rotatable component 11 and extends outwardly in the radial direction of the rotatable component 11. The beam component 3 is disposed on the mounting plate 15.

[0089] According to the embodiments of the present disclosure, Figure 1 and Figure 2As shown, the frame includes a first mounting plate 151 and a second mounting plate 152. The first mounting plate 151 is arranged on a first side of the second end. The second mounting plate 152 is arranged on a second side of the second end opposite to the first side. The beam assembly 3 includes a plurality of beam modules 30, a portion of the beam modules 30 are arranged on the first mounting plate 151, and another portion of the beam modules 30 are arranged on the second mounting plate 152. The output ends of the beam modules 30 are all arranged facing the axis of the rotatable assembly 11, so that the particle beam output by each beam module 30 converges at a point on the axis of the rotatable assembly 11.

[0090] In some exemplary embodiments, Figure 1 and Figure 2 As shown, each beam module 30 in the beam assembly 3 includes but is not limited to being constructed in the same structure. Such a modular design not only shortens the processing cycle of the beam module 30, but also makes it easy to match with the external structure, thereby improving the adaptability and interchangeability of the beam module 30.

[0091] In some exemplary embodiments, the beam module 30 includes a beam module base, a collimation mount, and a flange arranged opposite to the collimation mount. Further, the beam module 30 also includes at least a high-energy accelerating tube and a V-shaped collimation unit. The high-energy accelerating tube is installed on the beam module base, and its output end is located in the cavity formed by the beam module base. A flange is provided at the output end of the high-energy accelerating tube to accurately position the high-energy accelerating tube and the beam module base, and the V-shaped collimation unit is arranged opposite to the collimation mount. The other end of the collimation mount opposite to the beam module base. In this way, the charged ions accelerated by the high-energy accelerating tube can be accurately emitted after collimation.

[0092] According to the embodiments of the present disclosure, Figure 7 As shown, the first mounting plate 151 and the second mounting plate 152 are coplanarly arranged to form a second mounting surface, and the beam assembly 3 is arranged on the second mounting surface. Figure 7 In the example shown, the second mounting surface may be located on the right side of the first mounting plate 151 and the second mounting plate 152 .

[0093] According to the embodiments of the present disclosure, Figure 7 As shown, the first mounting plate 151 and / or the second mounting plate 152 are configured as a substantially fan-shaped structure.

[0094] According to the embodiments of the present disclosure, Figure 7 As shown, different numbers of beam modules 30 are disposed on the first mounting plate 151 and the second mounting plate 152 .

[0095] In some exemplary embodiments, Figure 7As shown, the first mounting plate 151 is disposed at the upper end of the rotatable component 11, and the second mounting plate 152 is disposed at the lower end of the rotatable component 11. Figure 7 The first mounting plate 151 and the second mounting plate 152 are coplanarly arranged in a plane formed by the y direction and the z direction shown. Specifically, the first mounting plate 151 and the second mounting plate 152 include but are not limited to a plate-like structure configured as a substantially fan-shaped structure. Further, a plurality of mounting holes 153 are arranged on the first mounting plate 151 and the second mounting plate 152 at intervals along the extension direction of the arc. Each mounting hole 153 corresponds to a beam module 30, and is suitable for accurately positioning the beam module 30 on the mounting plate along the circumferential direction.

[0096] In some exemplary embodiments, Figure 7 As shown, the curvature of the arc structure formed by the first mounting plate 151 is configured to be greater than the curvature of the arc structure formed by the second mounting plate 152. Specifically, the number of mounting holes provided on the first mounting plate 151 is also correspondingly configured to be greater than the number of through holes provided on the second mounting plate 152. For example, three through holes may be provided on the first mounting plate 151, and two through holes may be provided on the second mounting plate 152, so that more beam modules 30 can be installed on the first mounting plate 151 along the circumferential direction of the rotatable component 11 than on the second mounting plate 152.

[0097] In some exemplary embodiments, Figure 7 As shown, the first mounting plate 151 includes but is not limited to being provided with three beam modules 30. Further, the second mounting plate 152 includes but is not limited to being provided with two beam modules 30. The beams of rays output by each beam module 30 converge on the axis of the rotatable component 11. It should be understood that the embodiments of the present disclosure are not limited thereto.

[0098] For example, according to another embodiment of the present disclosure, the same number of beam modules 30 are disposed on the first mounting plate 151 and the second mounting plate 152 .

[0099] For another example, the beam module 30 may be disposed on only the first mounting plate 151 or the second mounting plate 152 , and a counterweight may be disposed on the other mounting plate.

[0100] According to the embodiments of the present disclosure, Figure 1 and Figure 7 As shown, the support assembly 13 includes a base 132 and two legs 131. The base 132 is configured as a pry-type structure. The two legs 131 are arranged at two opposite ends of the base 132, and a rotatable assembly 11 is rotatably arranged between the two legs 131.

[0101] In some exemplary embodiments, the base 132 includes a crossbeam and a longitudinal beam, which are connected in sequence to form a skid-type structure. Further, two legs 131 are relatively mounted on two crossbeams or longitudinal beams. Furthermore, the first end 111 and the second end 112 of the rotatable component 11 are rotatably mounted on the legs 131. In order to make the rotatable component 11 rotate smoothly relative to the legs 131, a bearing can be arranged between the rotatable component 11 and the legs 131. In addition, in order to facilitate the transportation of the rack and the radiation device, a lifting ring 133 can also be set on the base 132.

[0102] According to an embodiment of the present disclosure, a driving assembly 17 may also be provided on the frame 1. The driving assembly 17 is suitable for driving the rotatable assembly 11 to rotate around an axis.

[0103] According to the embodiments of the present disclosure, Figure 7 As shown, the driving assembly 17 includes a ring gear 171 and a driving portion 172. The ring gear 171 is coaxially disposed on the outer wall of the first end of the rotatable assembly 11. The driving portion 172 is transmission-connected to the ring gear 171 and is suitable for outputting torque to the ring gear 171.

[0104] According to an embodiment of the present disclosure, a brake assembly may also be provided on the frame 1 , and the brake assembly is suitable for limiting further rotation of the rotatable assembly 11 .

[0105] In some exemplary embodiments, the driving unit 172 may include a motor, a coupling and a reducer, and the brake assembly includes an electromagnetic brake. The output shaft of the motor is connected to the electromagnetic brake and the reducer through a coupling, and the output end of the reducer is connected to a pinion gear provided on the leg 131 through a synchronous belt, and the pinion gear is meshed with a ring gear 171 provided on the rotatable component 11 to drive the rotatable component 11 to rotate around the axis AX1. The synchronous belt is also equipped with a tensioning device to maintain the stability of the driving process. In addition, compared with the chain drive method, the use of synchronous belt drive is also conducive to reducing noise and improving transmission efficiency to meet the design requirements of the radiation device.

[0106] Furthermore, the frame 10 may also be configured with a proximity switch, which is communicatively connected to the electromagnetic brake to actively brake the rotatable component 11 when the rotatable component 11 rotates beyond a preset angle, and the preset angle includes but is not limited to ±180°.

[0107] According to the embodiments of the present disclosure, Figure 7 As shown, a detection assembly 18 is also provided on the frame 1. The detection assembly 18 is suitable for detecting the rotation speed and / or circumferential position of the rotatable assembly 11.

[0108] In some exemplary embodiments, the detection component 18 includes but is not limited to using an encoder. In detail, the encoder is arranged on a leg 131. Further, a code disk suitable for being detected by the leg 131 is also arranged on the outer wall of the rotatable component 11 to detect the rotation angle of the rotatable component 11 in real time.

[0109] In the process of realizing the inventive concept of the present disclosure, the inventors have discovered through research that how to perform multi-angle ultra-high dose rate radiation on a designated location within a short period of time (eg, within hundreds of milliseconds) is a problem that needs to be solved urgently.

[0110] According to one aspect of the present disclosure, a calibration device for an ultra-high dose rate radiation device is provided, wherein the ultra-high dose rate radiation device includes a plurality of beam modules for emitting multiple radiation beams, and the calibration device includes: a calibration target assembly, including a target portion, wherein the target portion is located in a predetermined radiation area of ​​the ultra-high dose rate radiation device during the calibration process; wherein the target portion is used as a reference to calibrate an intersection deviation of the multiple radiation beams converging in the predetermined radiation area.

[0111] In some exemplary embodiments, a calibration target assembly is provided, and its target portion is used as a reference to calibrate the intersection deviation of the multiple radiation beams at the predetermined radiation area, so that the multiple radiation beams can be converged in the predetermined radiation area, and the intersection deviation meets the expected requirements. It is possible to enable the calibrated multiple beam modules to perform ultra-high dose rate radiation at multiple angles on the same designated position.

[0112] Figure 8 The structure diagram of the calibration target assembly according to the embodiment of the present disclosure is schematically shown. Figure 8 (a) is the main view of the calibration target assembly. Figure 8 (b) is a side view of the calibration target assembly.

[0113] Figure 3 shows the schematic location of the calibration equipment, refer to Figure 3 , the calibration device may be located in the rotatable component 11. In some embodiments, the calibration device may include a calibration target assembly 20. The calibration target assembly 20 includes a target portion, wherein the target portion is located in a predetermined radiation area of ​​the radiation device 100 during the calibration process; wherein the target portion is used as a reference to calibrate the intersection deviation of multiple radiation beams converging in the predetermined radiation area.

[0114] For example, the beam module may include an electron linear accelerator. The radiation beam may include an X-ray beam. The predetermined radiation area may be an area in the radiation device 100 where radiotherapy is allowed, for example, the rotatable component 11 has a receiving space that can accommodate the target object to be radiotherapy. The predetermined radiation area may be a fixed area in the receiving space, for example, the lesion of the patient to be radiotherapy is placed in the fixed area and then receives radiotherapy.

[0115] In some embodiments, the radiation device 100 may include one or more predetermined radiation areas. When the radiation device 100 includes multiple predetermined radiation areas, multiple calibration devices may be provided to provide calibration functions simultaneously or asynchronously, or a single calibration device may be provided to provide calibration functions by changing positions between multiple predetermined radiation areas.

[0116] In some embodiments, the distances between the beam emission positions of the multiple beam modules and the target portion are substantially equal, which is beneficial for making the radiation effects of the beam modules on the radiotherapy area substantially consistent and also beneficial for the accuracy of calibration.

[0117] Exemplarily, the rotatable component 11 can rotate around its rotation axis AX1, thereby driving the first beam module 301, the second beam module 302, the third beam module 303, the fourth beam module 304 and the fifth beam module 305 to rotate. For example, during the calibration process, the center of the target is located at the rotation axis AX1 of the rotatable component 11. Therefore, during the rotation process, the rotatable component 11 can rotate around the predetermined radiation area. During the rotation process, by switching different beam modules to emit beams, the same predetermined radiation area (such as a lesion) can be irradiated at different angles, wherein the radiation beam emitted by each beam module can achieve the effect of ultra-high dose rate radiation. Multiple beam modules can emit beams in order and in relative position to the predetermined radiation area, or in a disordered order. Even when necessary, beams can be emitted for treatment at the same time.

[0118] By setting a plurality of beam modules of different angles on a rotatable component 11, the beam modules generating radiation are switched to achieve the purpose of rapidly performing irradiation treatment at multiple angles in a very short time required in flash radiotherapy. That is, after calibration, the rotatable component 11 and the plurality of beam modules cooperate to achieve irradiation of a predetermined radiation area at ultra-high dose rates at multiple angles.

[0119] Exemplarily, the target portion serves as a reference, which means that by simulating the beam output of multiple beam modules, a simulated radiation beam can be guided as a reference to hit a predetermined radiation area, or multiple beam modules can be made to actually output beams, which serves as a reference to guide multiple actual beams to hit a predetermined radiation area.

[0120] Whether the target is hit by a simulated radiation beam or by an actual beam, the situation where multiple radiation beams converge in a predetermined radiation area can be characterized in a visual or non-visual manner. Non-visual methods may include data processing methods such as signal detection or dose detection. By characterizing in a visual or non-visual manner, the intersection deviation of multiple radiation beams in a predetermined radiation area can be calibrated. The intersection deviation includes the distance between the impact position of any radiation beam in the predetermined radiation area and a specific position, or the distance between the impact positions of any two radiation beams in the predetermined radiation area.

[0121] In some embodiments, the target portion is used as a reference to calibrate the intersection deviation of multiple beam modules converging in a predetermined radiation area, including at least one of the following: simulating the beam output of multiple beam modules through multiple beams of visible light, simulating the multiple radiation beams hitting the target portion, and manually testing or image identifying the hitting positions and intersection deviations of the multiple beams of visible light in a visual manner; actually emitting beams through multiple beam modules, detecting the dose of the radiation beam in the predetermined radiation area by a dose detection method, and calibrating the intersection deviation by the difference between the radiation beam doses; actually emitting beams through multiple beam modules, detecting the radiation signal of the radiation beam in the predetermined radiation area by a radiation signal detection method, and calibrating the intersection deviation by the representation of the radiation energy, the number of rays or the radiation scanning image.

[0122] It can be understood that the above-mentioned method of simulating the beam emission of multiple beam modules, the dose detection method and the radiation signal detection method can be used one by one or in sequence.

[0123] According to an embodiment of the present disclosure, a calibration target assembly 20 is provided, and its target portion is used as a reference to calibrate the intersection deviation of multiple radiation beams at a predetermined radiation area, so that the multiple radiation beams can be converged at the predetermined radiation area, and the intersection deviation meets the expected requirements. It is possible to enable multiple calibrated beam modules to perform ultra-high dose rate radiation at multiple angles on the same designated position.

[0124] Various embodiments of using the target portion as a reference to calibrate the intersection deviation of multiple beam modules in a predetermined radiation area are further described below.

[0125] In some embodiments, the calibration device further comprises a plurality of laser assemblies, which are mounted one by one at the beam emission positions of the plurality of beam modules, wherein the plurality of laser assemblies are used to emit a plurality of laser beams to the target portion to simulate the intersection position of the plurality of radiation beams at the predetermined radiation area.

[0126] Each laser assembly is installed at the beam emission position of the corresponding beam module, and the installation axis coincides with the beam axis of the corresponding beam module for adjustment and positioning during installation. After the calibration is completed, the laser assembly can be removed.

[0127] For example, the intersection position includes the area where multiple laser beams converge at the target, which includes one or more points hit by each laser beam. The intersection deviation between the laser beams can be reflected by the distance between the points of each laser beam, or the distance between the point of each laser beam and the target point. When the intersection deviation does not meet the requirements, one or more of the angle, height, position, collimation parameters, etc. of the beam module can be adjusted, and then multiple laser components can be reused to emit multiple laser beams to the target.

[0128] According to an embodiment of the present disclosure, by providing a laser component to simulate the emission of multiple radiation beams, the intersection deviation can be efficiently measured in a low-cost and visual manner, and it can be quickly discovered whether the intersection position meets the conditions and then determine whether to adjust the beam module.

[0129] For example, the target portion may include a structure such as a plane mirror, a polygonal mirror, a flat plate, a cube, or a sphere, which can display the impact point of each laser beam in a visual manner.

[0130] For example, in the case where the target portion includes a single plane mirror or a flat plate, a target point can be marked thereon, and the laser assembly corresponding to the first beam module 301 is first moved to a specific position and then emits a laser to the target portion, and the position of its hit point is recorded. Then, by rotating the rotatable assembly 11, each of the remaining beam modules is moved to the same position in turn, and the corresponding laser assembly emits a laser and then records the position of the hit point. After obtaining the hit point positions of all laser assemblies, the distance between each hit point and the target point, as well as the distance between the hit points, can be calculated.

[0131] For example, when the target portion includes a polygonal mirror, it may include a prism structure formed by multiple plane mirrors. Multiple laser assemblies are made to emit lasers to the polygonal mirror at the same time to simulate the situation where multiple beam modules emit beams at the same time. The intersection deviation is measured by the impact point of each laser beam presented by the polygonal mirror.

[0132] For example, when the target portion includes a cube, it may be a cube, a cuboid, or other polyhedrons. Multiple laser assemblies are made to emit lasers to the cube at the same time to simulate the situation where multiple beam modules emit beams at the same time. The intersection deviation is measured by the impact point of each laser beam presented by the cube.

[0133] For example, in the case where the target portion includes a sphere 201 , further description will be given below.

[0134] In some embodiments, the center of the sphere 201 is located at the rotation axis AX1 of the rotatable component 11 during the calibration process.

[0135] The rotatable component 11 can rotate around its rotation axis AX1, and can rotate around the predetermined radiation area during the rotation process. Ideally, the rotatable component 11 always rotates around the same treatment center, and multiple beam modules are no longer calibrated during this process. The same treatment center can be the center position of the predetermined radiation area, and the center position is simulated by the center of the sphere. The sphere 201 can occupy part or all of the predetermined radiation area.

[0136] According to the embodiments of the present disclosure, by placing the center of the sphere on the rotation axis AX1, an actual radiotherapy scenario can be simulated, calibration accuracy can be improved, data deviation can be reduced, and the accuracy and consistency of the calibration process and the actual radiotherapy process can be maintained.

[0137] In some embodiments, the sphere 201 is drawn with interwoven longitudes and latitudes, wherein the longitudes and latitudes are used to represent the intersection deviation between any two laser beams in the multiple laser beams.

[0138] The longitude and latitude lines on the sphere 201 can be used as a reference grid for detecting and adjusting the alignment of the laser beams. For example, if two laser beams should intersect at one point on the sphere 201, but actually the grid shows them intersecting at different points, this deviation can be corrected by adjusting the position or angle of the laser emitters.

[0139] According to an embodiment of the present disclosure, the longitude and latitude lines provide a visual framework for accurately measuring the intersection deviation of each laser beam and visually simulating and displaying the intersection position.

[0140] In some embodiments, multiple beam modules are distributed in a ring around the rotatable component 11, and the sphere 201 is used as a reference to guide multiple laser beams to converge on the surface of the sphere. Further, the impact points of the multiple laser beams on the sphere 201 can be guided to be located on the same circular cross section.

[0141] Multiple beam modules are evenly distributed around the rotatable component 11, and can emit radiation beams from different angles simultaneously or asynchronously. By calibrating so that the impact points of all laser beams on the sphere 201 are located on the sphere 201, the expected intersection position can be obtained by emitting multiple radiation beams during the actual radiotherapy process. Maintaining the same circular cross-section is conducive to achieving the proximity of the impact position and thus achieving the flash therapy radiation effect of ultra-high dose rate.

[0142] In some embodiments, the radius of the sphere 201 is less than or equal to a predetermined threshold, and the center of the sphere 201 coincides with the target point position in the predetermined radiation area, wherein the predetermined threshold is used to constrain the error between the impact position of any laser beam and the target radiotherapy position.

[0143] By controlling the radius and the center position of the sphere 201, the irradiation range of the laser beam can be controlled, that is, when any laser beam can irradiate the sphere 201, the distance between its impact point and the center of the sphere is equal to the predetermined threshold, and thus is less than the error value equal to the predetermined threshold. When the predetermined threshold is less than or equal to the predetermined error value, it is quickly confirmed in a visual manner which laser beams meet the intersection deviation because they irradiate the sphere 201, and which laser beams do not meet the intersection deviation because they do not irradiate the sphere 201, so as to adjust the beam modules corresponding to the laser beams that do not meet the intersection deviation.

[0144] For example, the predetermined threshold value or the predetermined error value may be determined according to the size of the lesion to be irradiated.

[0145] Therefore, the sphere 201 can be used to realize the beam convergence center of multiple beam modules (such as multiple linear accelerators) in the geometric space, and the error between each radiation beam and the intersection point is less than a predetermined error value, such as ±5mm, thereby achieving ultra-high dose irradiation at the designated lesion location.

[0146] Exemplarily, the sphere 201 may be made of plastic, iron, lead or stainless steel, and its diameter may be 10 mm (for example only), and the coaxial error between the sphere center and the rotation axis AX1 is ≯0.2 mm, and the processing error is ensured by precision processing of CNC machine tools.

[0147] like Figure 8 As shown, the calibration target assembly 20 also includes a support frame. The support frame includes: a support base 202, which is installed on the inner wall of the rotatable assembly 11, and the curvature of the bottom surface of the support base 202 matches the curvature of the installation area on the inner wall of the rotatable assembly 11; a connecting member 203, whose first end is connected to the support base 202 and whose second end is connected to the sphere 201.

[0148] Among them, the bottom surface of the support base 202 serves as the component installation surface, which fits with the inner wall curved surface of the rotatable component 11 (that is, the curvature matches), and is conveniently installed on the inner circle (inner wall arc surface) of the rotatable component 11. The inner circle installation position is finely machined, and the machining error is guaranteed by fine machining of CNC machine tools.

[0149] The following further describes the actual beam emission through multiple beam modules, the use of dose detection to detect the dose of the radiation beam in a predetermined radiation area, and the calibration of the intersection deviation through the difference between the radiation beam doses.

[0150] In some embodiments, the target portion includes at least one dose detection module for detecting a first actual dose of the radiation beam emitted by each beam module; wherein the difference between the first actual dose and the first theoretical dose of the radiation beam emitted by each beam module is used to characterize the intersection deviation.

[0151] It can be understood that when multiple beam modules can intersect in a predetermined radiation area, and the intersection deviation is less than a certain value, the dose of the radiation beam emitted by each beam module in the predetermined radiation area can be estimated, which is called the first theoretical dose. Therefore, the intersection deviation can be reflected by the difference between the actual detection dose and the theoretical dose. For example, it can be estimated that there is a certain deviation between the distance between the radiation beam emitted by each beam module and the target point.

[0152] According to the embodiments of the present disclosure, an accurate comparison between the actual dose and the theoretical dose of the radiation beam emitted by each beam module can be achieved, thereby effectively characterizing the intersection deviation, which can not only improve the calibration efficiency and reliability, but also improve the dose accuracy and consistency of radiotherapy.

[0153] In some embodiments, at least one dose detection module includes at least one dosimeter for detecting a first actual dose of the radiation beam emitted by each beam module.

[0154] A dosimeter is a device used to measure the dose of radiation (such as X-rays and gamma rays). For example, the radiation intensity can be measured based on a radiation-sensitive detector, that is, when radiation particles in the environment pass through the detector, they will react with the radiation-sensitive medium, which will then be collected by the detector and converted into an electrical signal. The electrical signal is further processed to calculate the radiation dose.

[0155] For example, at least one dosimeter may include a single dosimeter whose radiation detection area has a fixed angle. By rotating the rotatable component 11, each beam module is rotated to the same angle in turn, and a radiation beam is emitted to the radiation detection area of ​​the dosimeter serving as the target, thereby realizing dose detection of multiple radiation beams.

[0156] In some embodiments, at least one dosimeter includes multiple dosimeters, multiple beam modules are distributed in a ring around the rotatable component 11 of the radiation device 100, and multiple radiation detection areas of the multiple dosimeters are distributed in a ring to correspond one-to-one to multiple beam emission positions of the multiple beam modules; wherein the multiple dosimeters are used to detect the first actual dose of each radiation beam in the multiple radiation beams in a one-to-one correspondence.

[0157] For example, the radiation detection area is used to reflect the radiation and measure the radiation dose passing through the area. Multiple dosimeters are independent dose detection devices.

[0158] According to the embodiments of the present disclosure, the dose of each beam module can be accurately measured, so that the intersection deviation between each beam module and the target point or other beam modules can be accurately evaluated.

[0159] In some embodiments, at least one dose detection module includes: at least one ionization chamber for detecting a second actual dose of the radiation beam emitted by each beam module; wherein the difference between the second actual dose and the first theoretical dose of the radiation beam emitted by each beam module is used to characterize the intersection deviation.

[0160] The ionization chamber contains a chamber filled with inert gas, with positive and negative electrodes in the chamber. When radiation is incident, it causes the gas in the tube to ionize. Under the action of the electric field, electrons move toward the anode and positive ions move toward the cathode. The electrons collected by the anode form a current in the circuit and are recorded, thereby measuring the radiation dose.

[0161] For example, at least one ionization chamber may include a single ionization chamber whose radiation detection area has a fixed angle. By rotating the rotatable component 11, each beam module is rotated to the same angle in turn, and a radiation beam is emitted to the radiation detection area of ​​the ionization chamber serving as a target, thereby realizing dose detection of multiple radiation beams.

[0162] In some embodiments, at least one ionization chamber includes multiple ionization chambers, multiple beam modules are distributed in a ring around the rotatable component 11 of the radiation device 100, and multiple ray incident angles of the multiple ionization chambers correspond one-to-one to multiple beam emission positions of the multiple beam modules to receive multiple radiation beams one-to-one; wherein the multiple ionization chambers are used to detect the second actual dose of each radiation beam in the multiple radiation beams one-to-one.

[0163] Fig. 9 The structure cross-sectional view of a rotatable assembly and a calibration target assembly according to an embodiment of the present disclosure is schematically shown. Fig.10 The structure top view of the rotatable assembly and the calibration target assembly according to the embodiment of the present disclosure is schematically shown. Fig.11 The diagram schematically shows the installation zero position state according to an embodiment of the present disclosure. The installation zero position is the initial state of the beam module installation.

[0164] Reference Figures 1 to 11 , the following describes the installation and calibration process of the beam module of the radiation device 100.

[0165] When the rotatable assembly 11 is installed, the first beam module 301, the second beam module 302, and the third beam module 303 are installed on the upper first mounting plate 151, and the fourth beam module 304 and the fifth beam module 305 are installed on the lower second mounting plate 152. The upper beam support is lifted by a sling to dock with the rotatable assembly 11, and is positioned with a fixing pin and then fastened with a screw; then the motor drum is driven to rotate 180°, and the lower beam module support is docked with the rotatable assembly 11, and is also positioned with a pin and fastened, and then the drum is rotated back to the working zero position.

[0166] Exemplarily, the first mounting plate 151 and the second mounting plate 152 include mounting holes 153 for mounting the beam module. The mounting surfaces of the first mounting plate 151 and the second mounting plate 152 are coplanar, and the distance control error between the surface and one end surface of the rotatable component 11 is ≯0.2mm. A plurality of positioning screws 154 are reserved near the mounting holes 153 to meet the front-to-back and left-to-right four-way adjustment functions, which is conducive to observing the positioning reference and adjusting the beam module during installation.

[0167] In order to facilitate installation and maintenance, multiple beam modules are modularly designed, which not only shortens the processing cycle, but also makes it easy to match with external interfaces and enhance interchangeability. The first mounting plate 151 or the second mounting plate 152 is made of aluminum and designed as an integrated structure, which is as light as possible while ensuring the support strength and rigidity; the center hole of the accelerating tube mounting flange of the beam module is finely processed, and the tolerance between the center line of the hole and the bottom surface of the installed mounting plate 15 is controlled to be ≯0.05mm to ensure the consistency of the height of the beam center line of each module.

[0168] A calibration target assembly 20 is arranged on the rotation axis of the rotatable assembly 11, and its target part includes a sphere 201. The sphere 201 is made of stainless steel, and the diameter of the sphere 201 is 10 mm. It is installed on the rotation axis of the rotatable assembly 11. The coaxial error between the sphere center and the rotation axis AX1 is ≯0.2 mm. The bottom surface of the support frame and the inner wall of the rotatable assembly are curved surfaces, and the processing error is ensured by fine processing of a CNC machine tool. The calibration target assembly 20 is adjustable in the front-to-back direction along the rotation axis AX1 of the rotatable assembly 11, so that the center of the sphere 201 coincides with the intersection point where the five radiation beams meet, which can meet the installation and adjustment of the on-site beam module.

[0169] With the calibration target assembly 20 as the positioning reference, the positions of the beam modules are adjusted in sequence by setting the positioning screws 154 of each mounting hole 153 on the first mounting plate 151 and the second mounting plate 152. The beam modules can be fastened after the laser beams at the front end of each beam module are irradiated on the spherical surface and the multiple laser beams are roughly located on the same circular cross section (try to locate them at the cross section of the sphere center).

[0170] A sphere 201 is provided for calibration, and its center coincides with the rotation axis AX1 of the rotatable component 11. The sphere 201 is used as a reference target for the beam convergence center of each beam module, and can be used for multi-directional adjustment and positioning installation of the beam module, and multiple beam modules are installed sequentially, and finally the beam convergence center of multiple beam modules distributed in an array is realized.

[0171] Based on the calibration device for the radiation device 100 as described above, a calibration method is also provided, which is further described below.

[0172] Fig.12 The flowchart of the calibration method according to the embodiment of the present disclosure is schematically shown. Figure 6As shown, the calibration method provided in this embodiment may include operations S1210 to S1220.

[0173] In operation S1210 , during a calibration process, a target of the calibration target assembly 20 is arranged at a predetermined radiation area of ​​the radiation device 100 .

[0174] In operation S1220 , a convergence deviation of a plurality of radiation beams converging at a predetermined radiation area is calibrated using the target portion as a reference.

[0175] In the embodiment of the present disclosure, the calibration process, for example, starts with the installation of each beam module and ends with the intersection deviation meeting the expected requirements. The expected requirements, for example, include making multiple laser beams hit the sphere 201, and the radius of the sphere 201 is less than or equal to a specific error, such as 5 mm.

[0176] In some embodiments, during the calibration process, the center of the target portion is located at the rotation axis AX1 of the rotatable component 11.

[0177] In some embodiments, a plurality of laser assemblies are controlled to emit a plurality of laser beams to a target portion to simulate a convergence position where a plurality of radiation beams converge at a predetermined radiation region.

[0178] In some embodiments, the target portion includes a sphere 201 , the center of which is located at the rotation axis AX1 of the rotatable component 11 during the calibration process.

[0179] In some embodiments, the intersection deviation between any two laser beams in the multiple laser beams is represented by the intertwined longitude and latitude lines on the sphere 201 .

[0180] In some embodiments, the sphere 201 is used as a reference to guide multiple laser beams to intersect on the surface of the sphere, including guiding multiple laser beams to intersect at a cross section where the same center of the circle is located.

[0181] In some embodiments, at least one dose detection module is used to detect a first actual dose of the radiation beam emitted by each beam module; and the difference between the first actual dose and a first theoretical dose of the radiation beam emitted by each beam module is used to characterize the intersection deviation.

[0182] In some embodiments, at least one dose detection module includes at least one dosimeter or at least one ionization chamber.

[0183] In some embodiments, at least one dosimeter includes multiple dosimeters, and multiple radiation detection areas of the multiple dosimeters are distributed in a ring shape to correspond one-to-one to multiple beam emission positions of multiple beam modules; so that the multiple dosimeters detect the first actual dose of each radiation beam in the multiple radiation beams one-to-one.

[0184] In some embodiments, at least one ionization chamber includes multiple ionization chambers, and the multiple ray incident angles of the multiple ionization chambers correspond one-to-one to the multiple beam emission positions of the multiple beam modules, so as to receive the multiple radiation beams one-to-one; so that the multiple ionization chambers detect the second actual dose of each radiation beam in the multiple radiation beams one-to-one.

[0185] In some embodiments, the distances between the beam emission positions of the plurality of beam modules and the target portion 130 are substantially equal, which is beneficial for making the radiation effects of the beam modules on the radiotherapy area substantially consistent and also beneficial for the accuracy of calibration.

[0186] Exemplarily, the rotatable component 11 may include a roller, a circular ring (or a fixed ring of other shapes, such as a hexagonal, triangular, or irregularly shaped fixed ring, etc.). The rotatable component 11 may rotate around its rotation axis AX1, thereby driving the first beam module 301, the second beam module 302, the third beam module 303, the fourth beam module 304, and the fifth beam module 305 to rotate. For example, during the calibration process, the center of the target portion is located at the rotation axis AX1 of the rotatable component 11. Thus, during the rotation process, the rotatable component 11 may rotate around the target portion 130. During the rotation process, by switching different beam modules to emit beams, the same target portion 130 (for example, a lesion) may be irradiated at different angles, wherein the radiation beam emitted by each beam module may achieve the effect of ultra-high dose radiation. Multiple beam modules may emit beams in a sequential order and in a relative position to a predetermined radiation area, or may emit beams in a disordered order. Even when necessary, beams may be emitted for treatment at the same time.

[0187] By setting a plurality of beam modules of different angles on a rotatable component 11, the beam modules generating radiation are switched to achieve the purpose of rapidly performing multiple angle irradiation treatment in a very short time required in flash radiotherapy. That is, after the calibration is completed, the rotatable component 11 and the plurality of beam modules cooperate to achieve ultra-high dose irradiation of a predetermined radiation area at multiple angles.

[0188] For example, the beam module may include an electron linear accelerator. The radiation beam may include an X-ray beam. For example, the rotatable component 11 has a receiving space therein, which can accommodate the target object to be radiotherapy. Figure 3 The schematic position of the target portion 130 is shown, which may be located in the rotatable component 11. For example, a lesion of a target object (such as a person) may be located in the target portion 130 and irradiated by one or more radiation beams.

[0189] It should also be noted that the directional terms mentioned in the embodiments, such as "upper", "lower", "front", "back", "left", "right", etc., are only for reference to the drawings and are not intended to limit the scope of protection of the present disclosure. Throughout the drawings, the same elements are represented by the same or similar reference numerals. Conventional structures or configurations will be omitted when they may cause confusion in the understanding of the present disclosure.

[0190] The embodiments of the present disclosure are described above. However, these embodiments are only for illustrative purposes and are not intended to limit the scope of the present disclosure. Although the embodiments are described above separately, this does not mean that the measures in the various embodiments cannot be used in combination to advantage. The scope of the present disclosure is defined by the attached claims and their equivalents. Without departing from the scope of the present disclosure, those skilled in the art may make a variety of substitutions and modifications, which should all fall within the scope of the present disclosure.

Claims

1. A radiation device, characterized in that: include: a rotatable component, the rotatable component being rotatable about a rotation axis; A beam assembly disposed on the rotatable assembly, wherein the beam assembly comprises a plurality of beam modules, each of the beam modules is used to emit a radiation beam, and the plurality of beam modules are arranged at intervals along the circumferential direction of the rotatable assembly; A power distributor is arranged on the rotatable component, wherein the power distributor is provided with a plurality of power distribution ports, and the plurality of power distribution ports are respectively connected to the plurality of beam modules, Wherein, the beam assembly and the power divider can rotate around the rotation axis along with the rotatable assembly.

2. The device according to claim 1, characterized in that The output end of each beam module faces the rotation axis of the rotatable component, and the radiation beam output by each beam module converges on the rotation axis.

3. The device according to claim 1 or 2, characterized in that: The radiation device also includes a pulse transformer arranged on the rotatable component, and the pulse transformer is used to convert a DC power supply of a first voltage into a pulse power supply of a second voltage, wherein the second voltage is higher than the first voltage, and the pulse transformer can rotate around the rotation axis with the rotatable component.

4. The device according to claim 1 or 2, characterized in that: The radiation device also includes a power source disposed on the rotatable component, the power source is connected to the pulse transformer, the power source is used to generate microwave energy, and the power source can rotate around the rotation axis along with the rotatable component.

5. The device according to claim 1 or 2, characterized in that: The radiation device also includes a power synthesizer disposed on the rotatable component, the power synthesizer is connected to the power source, the power synthesizer is used to synthesize the microwave energy provided by the power source, and the power synthesizer can rotate around the rotation axis along with the rotatable component.

6. The device according to claim 1 or 2, characterized in that: The radiation device further includes a plurality of waveguides, the plurality of power distribution ports are respectively connected to the plurality of beam modules through the plurality of waveguides, and the waveguide lengths of at least two of the plurality of waveguides are unequal.

7. The device according to claim 1 or 2, characterized in that: The rotatable component includes a first end and a second end disposed opposite to each other along the extension direction of the rotation axis; The radiation device further includes a mounting plate, which is disposed on an outer wall of the second end of the rotatable component and extends outwardly along a radial direction of the rotatable component; and The beam assembly is arranged on the mounting plate.

8. The device according to claim 7, characterized in that The mounting plate comprises: a first mounting plate disposed on a first side of the second end; and a second mounting plate disposed on a second side of the second end opposite to the first side, and A portion of the plurality of beam modules is disposed on the first mounting plate, and another portion of the plurality of beam modules is disposed on the second mounting plate.

9. The device according to claim 8, characterized in that The first mounting plate and one side surface of the second mounting plate are coplanarly arranged to form a second mounting surface, and the plurality of beam modules are arranged on the second mounting surface.

10. The device according to claim 7 or 8, characterized in that A plurality of mounting holes are respectively provided on the first mounting plate and the second mounting plate, and the plurality of mounting holes are used to respectively mount the plurality of beam modules and position the plurality of beam modules on the mounting plates along a circumferential direction.

11. The device according to claim 1 or 2, characterized in that: The radiation device further comprises a driving component, wherein the driving component is used for driving the rotatable component to rotate around the rotation axis.

12. The device according to claim 11, characterized in that The rotatable assembly includes a roller; The driving assembly comprises: a ring gear coaxially arranged on the outer wall of the first end of the drum; and a driving part drivingly connected to the ring gear and suitable for outputting torque to the ring gear.

13. The device according to claim 1 or 2, characterized in that At least one of the beam modules includes an electron linear accelerator.

14. The device according to claim 1 or 2, characterized in that The radiation device also includes an adjustment component, which is used to adjust the position of the pulse transformer relative to the power distributor and keep the pulse transformer at a preset position.

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