Composition with effects of preventing hair breakage and repairing as well as preparation method and application of composition

Abstract

The invention discloses a composition with broken hair preventing and repairing effects as well as a preparation method and application thereof, the composition comprises the following components in percentage by mass: 10-40% of hydrolyzed rice protein, 5-20% of tricholoma matsutake extract, 5-30% of sodium hyaluronate, 5-20% of panthenol and the balance of water, the preparation method of the composition comprises the following steps: mixing the hydrolyzed rice protein, the tricholoma matsutake extract, the sodium hyaluronate, the panthenol and the water, and stirring until the mixture is completely dissolved to obtain the composition, and applying the composition to the preparation of the shampoo. Through mutual coordination of the hydrolyzed rice protein, the tricholoma matsutake extract, the sodium hyaluronate and the panthenol in the raw materials of the composition, the composition not only can repair damaged hair in the hair and in the aspect of chemical bond action between keratin, has a remarkable anti-breakage effect, but also is mild, safe, degradable and friendly to scalp, and has a good application prospect. In addition, the preparation method is simple and can be applied to products such as shampoo, hair conditioners, hair masks and hair care essence.

Description

Technical Field

[0001] The present invention relates to the technical field of daily cosmetics, and in particular to a composition with hair breakage prevention and repairing effects, and a preparation method and application thereof. Background Art

[0002] Hair loss is increasingly becoming a problem for modern people, especially women. When hair grows to a certain length, it will split and break. With the increase of work pressure, the accelerated pace of life, environmental impact, and the use and popularity of styling products such as hair dyeing and perming, the patients with hair loss and hair breakage are gradually getting younger. The fundamental cause of hair loss is the atrophy and degeneration of hair follicles, which cannot absorb nutrients from the surrounding hair, and the hair naturally stops growing. The commonly used anti-hair breakage repair ingredients in shampoos on the market are silicone oil and polymer conditioners, which have a certain anti-hair breakage repair effect on hair, but long-term use is easy to deposit on the hair, which is not friendly to the hair and not very healthy for the scalp. Summary of the invention

[0003] In order to solve the problems raised in the above background technology, the purpose of the present invention is to provide a composition with anti-hair breakage and repairing effects, and a preparation method and application thereof, wherein the composition is mild, safe, degradable, and scalp-friendly.

[0004] To achieve the above object, the present invention adopts the following technical solutions:

[0005] The first object of the present invention is to provide a composition with anti-breakage and hair repairing effects, which comprises, by mass percentage, 10-40% of hydrolyzed rice protein, 5-20% of Tricholoma matsutake extract, 5-30% of sodium hyaluronate, 5-20% of panthenol and the remainder of water.

[0006] The second object of the present invention is to provide a method for preparing the above-mentioned composition with the effect of preventing hair breakage and repairing hair, comprising the following steps: mixing hydrolyzed rice protein, Tricholoma matsutake extract, sodium hyaluronate, panthenol and water, and stirring until completely dissolved to obtain the composition.

[0007] As a further scheme of the present invention: the preparation step of the hydrolyzed rice protein: water is heated to 55° C. in a thermostatic water bath, rice protein is first added, 1 mol / L NaOH solution is added to the thermostatic water bath, the pH value of the reaction system is adjusted to 8.0, trypsin is added to hydrolyze the rice protein for 2.0 h, then the temperature is adjusted to 55° C. again, and the pH value of the reaction system is adjusted to 8.0 with 1 mol / L NaOH solution, and alkaline protease is added to hydrolyze the rice protein for 2.0 h; after hydrolysis, the enzymolysis solution is dehydrogenated, the enzyme dehydrogenation condition is 90-100° C. and maintained for 5-10 min, the enzymolysis solution is cooled to room temperature after the enzyme dehydrogenation, then filtered, and finally the filtrate is spray-dried under the conditions of an inlet air temperature of 120-150° C., an outlet air temperature of 65-90° C., and a homogenization pressure of 20-35 MPa to obtain the hydrolyzed rice protein;

[0008] As a further scheme of the present invention: the preparation steps of the Tricholoma matsutake extract are: reflux extraction of Tricholoma matsutake dried slices to obtain a Tricholoma matsutake crude extract with a density of 1.01-1.10 g / cm; column chromatography of the extracted Tricholoma matsutake crude extract at a temperature of 10-40°C, and reduced pressure concentration to obtain Tricholoma matsutake extract; freeze-drying and crushing the prepared Tricholoma matsutake extract to obtain the Tricholoma matsutake extract.

[0009] As a further solution of the present invention: the weight ratio of the trypsin to the rice protein is 0.01:1, and the weight ratio of the alkaline protease to the rice protein is 0.01:1.

[0010] As a further solution of the present invention: the resin used in the column chromatography is H103 macroporous resin with a diameter-to-height ratio of 1:8.

[0011] As a further solution of the present invention: the time for the Tricholoma matsutake crude extract to be adsorbed by the resin is 2 to 3 hours, the volume ratio of the resin to the Tricholoma matsutake crude extract is 1:1, and the column flow speed of the Tricholoma matsutake crude extract is 2 to 3 BV / h.

[0012] As a further solution of the present invention: the eluent used for the column chromatography is 40% by volume ethanol, the ratio of the eluent to the resin is 3:1, and the elution rate of the eluent is 2 to 3 BV / h.

[0013] Another object of the present invention is to provide a use of the above composition with hair breakage prevention and repairing effects in the preparation of shampoo.

[0014] The specific applications are as follows:

[0015] A shampoo, comprising the following raw materials in percentage by mass:

[0016]

[0017] As a further scheme of the present invention: the preparation method of the shampoo comprises the following steps: adding the phase A raw materials into the reactor in sequence, stirring and homogenizing until completely dissolved, and then heating to 80°C, then adding the phase B into the reactor in sequence, stirring until completely dissolved, keeping the temperature for 30 minutes and then cooling, cooling to below 45°C, adding phases C and D into the reactor, and stirring evenly to obtain the shampoo.

[0018] Compared with the prior art, the present invention has the following beneficial effects: the raw materials of the composition of the present invention contain hydrolyzed rice protein, Tricholoma matsutake extract, sodium hyaluronate and panthenol, wherein the hydrolyzed rice protein is rich in substances such as amino acids, can promote fibroblasts to produce collagen, and has multiple functions such as moisturizing, antistatic, skin conditioning and hair conditioning, and the pine mushroom polysaccharide contained in the Tricholoma matsutake extract can promote the removal of free radicals in the body, increase the body's antioxidant capacity, and have a significant protective effect on immune damage caused by radiation; sodium hyaluronate can not only significantly improve skin moisture, maintain elasticity and moisture in the field of skin care, but also In the field of hair care, its stable water-soluble polymer structure can form a protective film, providing deep moisturizing and nourishment for the hair; panthenol can prevent hair loss, promote hair growth, keep hair moisturized, reduce hair split ends, prevent dryness and breakage, and protect, repair and care for the hair. Through the mutual coordination of the above components, the composition not only repairs damaged hair inside the hair and the chemical bonds between keratin, and has a significant anti-breakage effect, but is also gentle, safe, degradable, and scalp-friendly. In addition, the preparation method is simple and can be applied to products such as shampoo, conditioner, hair mask and hair care essence. DETAILED DESCRIPTION

[0019] The present invention will be further described below in conjunction with the embodiments.

[0020] Example 1

[0021] The present embodiment provides a method for preparing a composition with the efficacy of preventing hair breakage and repairing hair, comprising the following steps: mixing 10% hydrolyzed rice protein, 15% Tricholoma matsutake extract, 20% sodium hyaluronate, 15% panthenol and 40% water, and stirring until completely dissolved to obtain the composition.

[0022] Example 2

[0023] The present embodiment provides a method for preparing a composition with the efficacy of preventing hair breakage and repairing hair, comprising the following steps: mixing 20% ​​hydrolyzed rice protein, 10% Tricholoma matsutake extract, 5% sodium hyaluronate, 10% panthenol and 55% water, and stirring until completely dissolved to obtain the composition.

[0024] Example 3

[0025] The present embodiment provides a method for preparing a composition with the efficacy of preventing hair breakage and repairing hair, comprising the following steps: mixing 15% hydrolyzed rice protein, 15% Tricholoma matsutake extract, 10% sodium hyaluronate, 10% panthenol and 50% water, and stirring until completely dissolved to obtain the composition.

[0026] Example 4

[0027] The present embodiment provides a method for preparing a composition with the efficacy of preventing hair breakage and repairing hair, comprising the following steps: mixing 30% hydrolyzed rice protein, 10% Tricholoma matsutake extract, 10% sodium hyaluronate, 5% panthenol and 45% water, and stirring until completely dissolved to obtain the composition.

[0028] Example 5

[0029] The present embodiment provides a method for preparing a composition with the efficacy of preventing hair breakage and repairing hair, comprising the following steps: mixing 25% hydrolyzed rice protein, 12% Tricholoma matsutake extract, 15% sodium hyaluronate, 10% panthenol and 38% water, and stirring until completely dissolved to obtain the composition.

[0030] Comparative Example 1

[0031] Comparative Example 1 is compared with Example 2, except that the present comparative example composition does not include hydrolyzed rice protein, and other components, amounts and preparation methods are the same as those of Example 2.

[0032] Comparative Example 2

[0033] The only difference between Comparative Example 1 and Example 2 is that the composition of this comparative example does not include Tricholoma matsutake extract, and the other components, dosages and preparation methods are the same as those of Example 2.

[0034] Comparative Example 3

[0035] The only difference between Comparative Example 1 and Example 2 is that sodium hyaluronate is not included in the composition of this comparative example, and the other components, amounts and preparation methods are the same as those of Example 2.

[0036] Comparative Example 4

[0037] The only difference between Comparative Example 1 and Example 2 is that panthenol is not included in the composition of this comparative example, and the other components, amounts and preparation methods are the same as those of Example 2.

[0038] Comparative Example 5

[0039] Comparative Example 5 is compared with Example 2, except that the hydrolyzed rice protein is replaced by hydrolyzed wheat protein in the comparative example composition, and the other components, amounts and preparation methods are the same as those in Example 2.

[0040] Comparative Example 6

[0041] The only difference between Comparative Example 6 and Example 2 is that the Tricholoma matsutake extract is replaced by ginseng extract in the composition of this comparative example, and the other components, dosages and preparation methods are the same as those in Example 2.

[0042] Comparative Example 7

[0043] The difference between Comparative Example 7 and Example 2 is that the sodium hyaluronate is replaced by glycerol glucoside in the composition of this comparative example, and the other components, amounts and preparation methods are the same as those of Example 2.

[0044] Comparative Example 8

[0045] The only difference between Comparative Example 8 and Example 2 is that panthenol is replaced by niacinamide in the composition of this comparative example, and the other components, amounts and preparation methods are the same as those of Example 2.

[0046] Application Example 1

[0047] A shampoo using a composition having the effect of preventing hair breakage and repairing hair, comprising the following raw materials in percentage by mass:

[0048] Phase A components: 12% sodium laureth sulfate, 6% cocamidopropyl betaine;

[0049] Phase B components: PEG-7 glyceryl cocoate 1%, citric acid 0.55%, phenoxyethanol 0.5%, sodium benzoate 0.4%;

[0050] Phase C components: 0.5% flavor, 8% composition prepared in Example 1, 0.6% sodium chloride

[0051] Phase D components: 0.1% disodium EDTA, 0.35% polyquaternium-10, 70% water;

[0052] The phase D raw materials are sequentially added into the reactor, stirred and homogenized until completely dissolved, and then heated to 80°C. Subsequently, the phase A is sequentially added into the reactor, stirred until completely dissolved, and then kept warm for 30 minutes and cooled. When the temperature is lower than 45°C, the phases B and C are added into the reactor, and stirred evenly to obtain the shampoo.

[0053] Application Example 2

[0054] The difference between Application Example 2 and Application Example 1 is that the composition prepared in Example 1 is replaced by the composition prepared in Example 2, and the addition amount of the composition prepared in Example 2 is 18%, and the addition amount of water is 60%.

[0055] Application Example 3

[0056] The difference between Application Example 3 and Application Example 1 is that the composition prepared in Example 1 is replaced by the composition prepared in Example 2, and the addition amount of the composition prepared in Example 2 is 15%, and the addition amount of water is 63%.

[0057] Application Example 4

[0058] The difference between Application Example 4 and Application Example 1 is that the composition prepared in Example 1 is replaced by the composition prepared in Example 2, and the addition amount of the composition prepared in Example 2 is 12%, and the addition amount of water is 66%.

[0059] Application Example 5

[0060] The difference between Application Example 5 and Application Example 1 is that the composition prepared in Example 1 is replaced by the composition prepared in Example 2, and the addition amount of the composition prepared in Example 2 is 10%, and the addition amount of water is 68%.

[0061] Application Comparative Example 1

[0062] Compared with Application Example 2, the only difference is that the composition prepared in Example 2 is replaced by the composition prepared in Comparative Example 1, and the other components, amounts and preparation methods are the same as those in Application Example 2.

[0063] Application Comparative Example 2

[0064] Compared with Application Example 2, the only difference is that the composition prepared in Example 2 is replaced by the composition prepared in Comparative Example 2, and the other components, amounts and preparation methods are the same as those in Application Example 2.

[0065] Application Comparative Example 3

[0066] Compared with Application Example 2, the only difference is that the composition prepared in Example 2 is replaced by the composition prepared in Comparative Example 3, and the other components, amounts and preparation methods are the same as those in Application Example 2.

[0067] Application Comparative Example 4

[0068] Compared with Application Example 2, the only difference is that the composition prepared in Example 2 is replaced by the composition prepared in Comparative Example 4, and the other components, amounts and preparation methods are the same as those in Application Example 2.

[0069] Application Comparative Example 5

[0070] Compared with Application Example 2, the only difference is that the composition prepared in Example 2 is replaced by the composition prepared in Comparative Example 5, and the other components, amounts and preparation methods are the same as those in Application Example 2.

[0071] Application Comparative Example 6

[0072] Compared with Application Example 2, the only difference is that the composition prepared in Example 2 is replaced by the composition prepared in Comparative Example 6, and the other components, amounts and preparation methods are the same as those in Application Example 2.

[0073] Application Comparative Example 7

[0074] Compared with Application Example 2, the only difference is that the composition prepared in Example 2 is replaced by the composition prepared in Comparative Example 7, and the other components, amounts and preparation methods are the same as those in Application Example 2.

[0075] Application Comparative Example 8

[0076] Compared with Application Example 2, the only difference is that the composition prepared in Example 2 is replaced by the composition prepared in Comparative Example 8, and the other components, amounts and preparation methods are the same as those in Application Example 2.

[0077] Application Comparative Example 9

[0078] Compared with Application Example 2, the only difference is that the composition prepared in Example 2 is not added, and the other components, dosages and preparation methods are the same as those in Application Example 2.

[0079] Test Case

[0080] Test object: Select a standard hair bundle with a similar degree of damage, completely immerse the damaged hair bundle in a hair bundle cleaning solution, ultrasonically clean it for 10 minutes, wash it with ordinary shampoo and dry it naturally, divide the hair bundle into 15 groups, each group has 10 hairs; weigh 2g of each of the commercially available shampoo, application examples 1-5 and application comparative examples 1-9, evenly apply each group of samples on each group of hair, massage for 3-5 minutes, wash it with deionized water, dry it, and obtain the test hair.

[0081] Index test: first use ZY-HD2K digital test microscope to measure the fiber cross-sectional area of ​​the test hair, then use XJ810 hair combing performance tester to test, fix a single test hair on the hair combing performance tester at a distance of 5cm, input the fiber cross-sectional area of ​​the test hair, set the stretching speed to 2.5cm / min, and perform tensile performance test. The index data include maximum force, tensile strength, elongation, energy absorption, and calculate the average value of each index; take the test hair smeared with the popular anti-hair breakage repair shampoo on the market as a reference, and set the maximum force average value to 1, the tensile strength average value to 1, the elongation average value to 1, and the energy absorption average value to 1, and calculate the relative data of the test hair smeared with other samples on this basis, where if the value is greater than 1, it indicates that the sample is better than the reference, otherwise, if the value is less than 1, it indicates that the sample is worse than the reference. The comparison results of the index test data are shown in Table 1 below.

[0082] Table 1 Comparison results of test data of various indicators of hair test

[0083]

[0084]

[0085] According to the comparison results of the test data of the above indicators, it can be seen that the anti-hair breakage and repairing effects of application examples 1-5 are better than those of commercially available anti-hair breakage and repairing shampoos, and the anti-hair breakage and repairing effects of application examples 1-9 are worse than those of commercially available anti-hair breakage and repairing shampoos, and their anti-hair breakage and repairing effects are average or not obvious. Application of comparative example 9 did not add the anti-hair breakage and repairing composition, and its test result was also the worst.

[0086] Trial evaluation: 300 volunteers with damaged hair were recruited, with 20 volunteers in each sample group. The sample trial period was 1 month. During the trial period, other shampoos were not allowed to be replaced, and other hair care products such as conditioners or hair oils were not used. After the trial, the volunteers scored the anti-hair breakage and repair effects based on the trial situation. The score ranged from 1 to 10, with 1 representing the worst and 10 representing the best. The average trial score of each group of samples was taken. The trial evaluation results are shown in Table 2 below.

[0087] Table 2 Trial evaluation results of test samples

[0088]

[0089]

[0090] According to the above trial evaluation results, the shampoo obtained by the technical solution of the present invention has excellent anti-hair breakage and repairing effects in sensory evaluation, and its repair and anti-hair breakage effects are mainly brought by the composition with anti-hair breakage and repairing effects of the present invention, and when any item in the composition is not added or replaced, it will affect the above effects. The composition of the present invention can repair damaged hair in terms of the chemical bonds inside the hair and between keratin proteins, and has a significant anti-hair breakage effect.

[0091] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A composition having the effect of preventing hair breakage and repairing hair, characterized in that: Calculated by mass percentage, the invention comprises 10-40% of hydrolyzed rice protein, 5-20% of Tricholoma matsutake extract, 5-30% of sodium hyaluronate, 5-20% of panthenol and the balance of water.

2. A method for preparing the composition having the effect of preventing hair breakage and repairing hair as claimed in claim 1, characterized in that: The following steps are involved: The hydrolyzed rice protein, Tricholoma matsutake extract, sodium hyaluronate, and panthenol are mixed with water and stirred until they are completely dissolved to obtain a composition.

3. The method for preparing a composition having the effect of preventing hair breakage and repairing hair according to claim 2, characterized in that: The preparation steps of the hydrolyzed rice protein are as follows: heating water to 55° C. in a constant temperature water bath, first adding rice protein, then adding 1 mol / L NaOH solution to the constant temperature water bath, adjusting the pH value of the reaction system to 8.0, adding trypsin to hydrolyze the rice protein for 2.0 hours, then adjusting the temperature to 55° C. again, adjusting the pH value of the reaction system to 8.0 with 1 mol / L NaOH solution, and adding alkaline protease to hydrolyze the rice protein for 2.0 hours; after hydrolysis, inactivating the enzyme in the enzymolysis solution at 90-100° C. for 5-10 minutes, cooling the enzymolysis solution to room temperature after the enzyme inactivation, then filtering, and finally spray drying the filtrate under the conditions of an inlet air temperature of 120-150° C., an outlet air temperature of 65-90° C., and a homogenizing pressure of 20-35 MPa to obtain the hydrolyzed rice protein.

4. The method for preparing a composition having the function of preventing hair breakage and repairing hair according to claim 2, characterized in that: The preparation steps of the Tricholoma matsutake extract are as follows: extracting Tricholoma matsutake dried slices by refluxing to obtain a Tricholoma matsutake crude extract having a density of 1.01 to 1.10 g / cm; subjecting the extracted Tricholoma matsutake crude extract to column chromatography at a temperature of 10 to 40° C., and concentrating under reduced pressure to obtain a Tricholoma matsutake extract; and freeze-drying and crushing the prepared Tricholoma matsutake extract to obtain the Tricholoma matsutake extract.

5. The method for preparing a composition having the effect of preventing hair breakage and repairing hair according to claim 3, characterized in that: The weight ratio of the trypsin to the rice protein is 0.01:1, and the weight ratio of the alkaline protease to the rice protein is 0.01:

1.

6. The method for preparing a composition having the function of preventing hair breakage and repairing hair according to claim 4, characterized in that: The resin used for the column chromatography is H103 macroporous resin, and the diameter-to-height ratio is 1:

8. The time for the crude extract of Tricholoma matsutake to be adsorbed by the resin is 2 to 3 hours. The volume ratio of the resin to the crude extract of Tricholoma matsutake is 1:

1. The column flow rate of the crude extract of Tricholoma matsutake is 2 to 3 BV / h. The eluent used for the column chromatography is 40% ethanol by volume. The ratio of the eluent to the resin is 3:1, and the elution rate of the eluent is 2 to 3 BV / h.

7. Use of the composition with hair breakage prevention and repairing efficacy as claimed in any one of claims 1 to 6 in the preparation of shampoo.

8. A shampoo, characterized in that: It is composed of the following raw materials in percentage by mass:

9. The method for preparing shampoo according to claim 8, characterized in that: The following steps are involved: Add the raw materials of phase A into the reactor in sequence, stir and homogenize until completely dissolved, then heat to 80°C, then add phase B into the reactor in sequence, stir until completely dissolved, keep warm for 30 minutes and then cool down to below 45°C, add phases C and D into the reactor, stir evenly to obtain the shampoo.

Images