A tumor organoid culture kit

By introducing limiting components and scaffold structures into the tumor organoid culture kit, the problem of inconvenient handling of reagent bottles and labels is solved, and efficient and safe tumor organoid culture operations are achieved.

CN119683149BActive Publication Date: 2025-07-25SHANDONG FUYOU LIFE SCI CO LTD
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Patent Information

Application Number
CN202510201118.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-02-24
Publication Date
2025-07-25
Estimated Expiration
2045-02-24

AI Technical Summary

Technical Problem

During the use of the existing tumor organoid culture kit, the reagent bottle and label are inconvenient to hold and place, and it is prone to mishandling and knocking, which increases the difficulty and cost of operation, and is inconvenient for efficient use.

Method used

A tumor organoid culture kit is designed, using a limiting component and a scaffold structure. Through the coordination of the scaffold and limiting component, the stable placement and separate storage of the reagent bottle and marker can be achieved. The scaffold can be taken out of the box and used alone, improving operating efficiency and safety.

Benefits of technology

It realizes the convenient handling of reagent bottles and labels, improves the efficiency of tumor organoid culture, ensures the safety and stability of reagent bottles, and reduces the difficulty and cost of operation.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention provides a tumor organoid culture kit, belonging to the technical field of kits. It includes a box body, one side of the box body is rotatably connected with a box cover, a bracket is inserted into the box body, reagent bottles and a label plate are placed on the bracket, and strips are inserted into the label plate; a limiting component, which is used to limit the reagent bottles and the label plate, and the limiting component is respectively connected with the bracket and the box body. By setting the limiting component and the bracket, the present invention can not only place the reagent bottles and the label plate, but also take out the bracket and the limiting component from the box body according to the usage process of the reagent bottles and the label plate, and then store and limit the reagent bottles and the label plate separately. After the bracket and the limiting component are taken out of the box body, it is more convenient for the operator to pick up and place the reagent bottles, improving the efficiency of tumor organoid culture and ensuring the safety during the repeated use of the reagent bottles.
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Description

Technical Field

[0001] The present invention relates to the technical field of kits, and in particular to a tumor organoid culture kit. Background Art

[0002] The test kit is a box used to hold chemical reagents for detecting chemical components, drug residues, virus types, etc. A tumor organoid culture kit is needed for tumor organoid culture. The tumor organoid culture kit generally stores sample cleaning solution, culture medium, primary clearing solution, stop solution, organoid digestion solution, cell culture plates and other related reagents and tools. In the test kit, plastic sponges are currently used to limit the reagent bottles, and disposable sealing bags are used to seal the cell culture plates.

[0003] When culturing tumor organoids, it is necessary to take out the reagent bottle from the reagent kit and place it on the experimental table, and then disassemble the cell culture plate from the disposable sealed bag and take it out. During the entire culturing process, the operator needs to repeatedly add reagents to the cell culture plate. Since there are many types of reagents and the reagent bottles look similar, it is easy to take the wrong bottle or knock it over if the reagent bottle is directly placed on the table. Since the friction of the plastic sponge in the reagent kit is large, it is inconvenient for the operator to directly use the reagent kit to conveniently and efficiently take and place the reagent bottle. This requires the operator to use other auxiliary tools to temporarily store and limit the reagent bottle, which increases the cost of tumor organoid culture. Therefore, the present invention provides a tumor organoid culture kit to meet the needs. Summary of the invention

[0004] The technical problem to be solved by the present invention is to provide a tumor organoid culture kit which can not only realize the placement of reagent bottles and label plates by setting a limiting component and a bracket, but also take out the bracket and the limiting component from the box body according to the use process of the reagent bottles and label plates, and then store and limit the reagent bottles and label plates separately. When the bracket and the limiting component are taken out from the box body, it is not only more convenient for operators to take and place reagent bottles, but also improves the efficiency of tumor organoid culture and ensures the safety of reagent bottles during repeated use. The above settings can solve the problem of inconvenient taking and placing of reagent bottles during use.

[0005] In order to solve the above technical problems, the present invention provides the following technical solutions:

[0006] A tumor organoid culture kit comprises a box body, one side of which is rotatably connected to a box cover, a bracket inserted in the box body, a reagent bottle and a label plate placed on the bracket, and a slat inserted on the label plate; a limiting component is used to limit the reagent bottle and the label plate, and the limiting component is respectively connected to the bracket and the box body.

[0007] Optionally, the limiting component includes a storage cylinder and a first storage plate fixedly connected to the bottom of the bracket. A second storage plate is fixedly connected to the bottom of the first storage plate. An extrusion block is fixedly connected to the inner wall of the box body.

[0008] Optionally, the storage cylinder is a cylindrical-profile barrel structure. A lightweight slot is provided on the storage cylinder. The storage cylinder and the bracket are of an integrally injection-molded structure.

[0009] Optionally, the position of the extrusion block corresponds to the position of the storage cylinder. An extrusion sheet is fixedly connected to the top of the extrusion block. The extrusion sheet is inserted into the lightweight slot. The middle position of the extrusion sheet has an inwardly concave arc.

[0010] Optionally, the size of the first storage plate is larger than that of the second storage plate. The first storage plate, the second storage plate and the bracket are of an integrally injection-molded structure.

[0011] Optionally, a first positioning block is fixedly connected to the top of the first storage plate. An insertion block is fixedly connected to the bottom of the marking plate. A slot adapted to the contour of the insertion block is provided at the middle position of the first positioning block.

[0012] Optionally, a second positioning block is fixedly connected to the top of the second storage plate. The overall contour of the second positioning block is spherical. The top of the second positioning block is of an open-segment structure.

[0013] Optionally, an arc-shaped sheet is fixedly connected to the bottom of the bracket. A support portion is fixedly connected to one end of the arc-shaped sheet. A limiting portion is fixed to the outer wall of the bottom of the arc-shaped sheet.

[0014] Optionally, the arc-shaped sheet has an inwardly inclined angle. The middle position of the arc-shaped sheet has an inwardly concave arc contour. Both the support portion and the limiting portion are of a curved arc structure.

[0015] Optionally, an inclined surface and a limiting block are fixedly connected to the inner wall of the box body. The inclined surface has an angle inclined towards the middle position of the box body. A slot with a "U"-shaped contour is provided at the middle position of the support portion. The position of the limiting block corresponds to the position of the "U"-shaped contour slot at the middle of the support portion.

[0016] Compared with the prior art, the present invention has at least the following beneficial effects:

[0017] In the above solution, compared with the prior art, the technical solution provided by the present application can not only place the reagent bottle and the label board, but also take out the bracket and the limiting component from the box body according to the usage process of the reagent bottle and the label board, and then store and limit the reagent bottle and the label board separately. After the bracket and the limiting component are taken out from the box body, it is not only more convenient for the operator to pick up and place the reagent bottle, which improves the efficiency of tumor organoid culture, ensures the safety during the repeated use of the reagent bottle, and perfects the practical application value of the reagent kit.

[0018] By setting structures such as the arc-shaped piece, the supporting part and the limiting part, not only the stability of the bracket during transportation is better, but also the impact force and collision force generated during transportation can be buffered and absorbed, thereby improving the safety of the reagent bottle during transportation. Moreover, the bracket can be disassembled from the box body and placed separately on the table, so that it is more convenient and efficient for the user to pick up and place the reagent bottle during the tumor organoid culture process. The cooperation between the arc-shaped piece and the supporting part makes the bracket more stable when the user places it on the table, ensuring that the bracket will not tip over or fall when the user picks up and places the reagent bottle, and improving the safety of the reagent bottle.

[0019] By setting the storage cylinder and the extrusion block, when the bracket is placed in the box body, the storage cylinder can form a structural cooperation with the extrusion block in the box body. The achieved effect makes the reagent bottle more stable and firm in the storage cylinder, thereby ensuring that the reagent bottle will not swing or shake in the storage cylinder during transportation, improving the safety of the reagent bottle. When the bracket is taken out from the box body, the storage cylinder can only simply position the reagent bottle and will not squeeze and limit it, so that it is easier and more convenient for the user to pick up and place the reagent bottle.

[0020] By setting the first storage board and the second storage board, the label board and the strip can be respectively limited and fixed. On the one hand, this improves the efficiency of the user to pick up and place the label board and the strip. On the other hand, it effectively ensures the safety and convenience of the label board and the strip during the secondary use process, thus making the entire tumor organoid culture process more concise and efficient. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] The drawings incorporated herein and constituting a part of the specification illustrate embodiments of the present invention and, together with the specification, are further used to explain the principles of the present invention and enable those skilled in the relevant art to implement and use the present invention.

[0022] Figure 1 It is a schematic perspective view of the first angle of the tumor organoid culture kit;

[0023] Figure 2 It is a schematic perspective view of the second angle of the tumor organoid culture kit;

[0024] Figure 3Schematic enlarged three-dimensional structure diagram of the cooperation between the box body and the box cover;

[0025] Figure 4 Schematic enlarged three-dimensional structure diagram of the cooperation of the limiting component;

[0026] Figure 5 Schematic first perspective three-dimensional structure diagram of the cross-section of the cooperation between the box body and the limiting component;

[0027] Figure 6 Schematic second perspective three-dimensional structure diagram of the cross-section of the cooperation between the box body and the limiting component;

[0028] Figure 7 Schematic first perspective three-dimensional structure diagram of the cross-section of the cooperation of the limiting component;

[0029] Figure 8 Schematic second perspective three-dimensional structure diagram of the cross-section of the cooperation of the limiting component;

[0030] Figure 9 Schematic enlarged three-dimensional structure diagram of the extrusion block;

[0031] Figure 10 Schematic enlarged three-dimensional structure diagram of the cooperation between the first storage plate and the second storage plate;

[0032] Figure 11 Schematic bottom view three-dimensional structure diagram of the marking plate;

[0033] Figure 12 Schematic top view three-dimensional structure diagram of the cooperation between the second storage plate and the slats.

[0034] Reference numerals:

[0035] 1. Box body; 101. Box cover; 102. Inclined surface; 103. Limiting block; 2. Bracket; 201. Arc-shaped piece; 202. Support part; 203. Limiting part; 3. Storage cylinder; 4. First storage plate; 401. First positioning block; 402. Second storage plate; 403. Second positioning block; 5. Extrusion block; 501. Extrusion piece; 6. Reagent bottle; 7. Marking plate; 701. Slats; 702. Insert block.

[0036] As shown in the figure, in order to clearly show the structure of the embodiments of the present invention, specific structures and devices are marked in the figure, but this is only for schematic purposes and is not intended to limit the present invention to this specific structure, device and environment. Those of ordinary skill in the art can adjust or modify these devices and environments according to specific needs. Detailed implementation manners

[0037] The following will describe in detail a tumor organoid culture kit provided by the present invention in conjunction with the accompanying drawings and specific embodiments. At the same time, it should be noted here that in order to make the embodiments more detailed, the following embodiments are the best and preferred embodiments. For some well-known technologies, those skilled in the art can also adopt other alternative methods for implementation; moreover, the accompanying drawings are only for more specifically describing the embodiments and are not intended to specifically limit the present invention.

[0038] It should be noted that in the specification, references to "an embodiment", "embodiments", "exemplary embodiments", "some embodiments", etc. indicate that the described embodiments may include specific features, structures, or characteristics, but not necessarily every embodiment includes such specific features, structures, or characteristics. Additionally, when combining embodiments to describe a specific feature, structure, or characteristic, implementing such a feature, structure, or characteristic in combination with other embodiments (whether explicitly described or not) should be within the knowledge of those skilled in the relevant art.

[0039] Generally, terms can be understood at least in part from their use in context. For example, depending at least in part on the context, the term "one or more" as used herein can be used to describe any feature, structure, or characteristic in a singular sense, or can be used to describe a combination of features, structures, or characteristics in a plural sense. Additionally, the term "based on" can be understood as not necessarily intended to convey a set of exclusive factors, but rather, depending at least in part on the context, can alternatively allow for the existence of other factors that may not be explicitly described.

[0040] It can be understood that the meanings of "on...", "above...", and "over..." in the present invention should be interpreted in the broadest manner, such that "on..." not only means "directly on" something, but also includes the meaning of being "on" something with intervening features or layers therebetween, and "above..." or "over..." not only means "above" or "over" something, but can also include the meaning of being "above" or "over" something with no intervening features or layers therebetween.

[0041] In addition, spatial relative terms such as "under...", "below...", "lower", "above...", "upper", etc. are used herein for convenience of description to describe the relationship of one element or feature to another or other elements or features, as shown in the accompanying drawings. Spatial relative terms are intended to cover different orientations in the use or operation of the device in addition to the orientation depicted in the drawings. The device may be oriented in other ways, and the spatial relative descriptive words used herein may be interpreted accordingly.

[0042] As Figures 1 to 5As shown in the figure, an embodiment of the present invention provides a tumor organoid culture kit, which includes a box body 1. One side of the box body 1 is rotatably connected with a box cover 101. A bracket 2 is inserted into the box body 1. A reagent bottle 6 and a label plate 7 are placed on the bracket 2. A strip 701 is inserted into the label plate 7. A limiting component is used to limit the reagent bottle 6 and the label plate 7. The limiting component is respectively connected to the bracket 2 and the box body 1. Both the box body 1 and the box cover 101 are made of hard paper shells. In the existing tumor organoid culture kits, usually a whole piece of plastic sponge is placed in the box body 1, and then placement holes are opened on the plastic sponge. The reagent bottle 6 is placed in the placement holes on the plastic sponge to achieve the limiting effect of the reagent bottle 6 by means of friction. The label plate 7 is stored in a disposable sealed bag. In this application, the bracket 2 and the limiting component are used to limit the reagent bottle 6 and the label plate 7 at the same time, without the need for separate placement. Compared with the prior art, the technical solution provided in this application can not only place the reagent bottle 6 and the label plate 7, but also take out the bracket 2 and the limiting component from the box body 1 according to the usage process of the reagent bottle 6 and the label plate 7, and then store and limit the reagent bottle 6 and the label plate 7 separately. After the bracket 2 and the limiting component are taken out from the box body 1, it is more convenient for the operator to pick up and place the reagent bottle 6, improving the efficiency of tumor organoid culture and perfecting the practical application value of the kit.

[0043] In this embodiment, as Figures 1 to 9As shown, an arc-shaped piece 201 is fixedly connected to the bottom of the bracket 2. One end of the arc-shaped piece 201 is fixedly connected to a support portion 202. A limiting portion 203 is fixed on the outer wall of the bottom of the arc-shaped piece 201. The arc-shaped piece 201 has an inwardly inclined angle. The middle position of the arc-shaped piece 201 has an inwardly concave arc profile. Both the support portion 202 and the limiting portion 203 are curved arc structures. An inclined surface 102 and a limiting block 103 are fixedly connected to the inner wall of the box body 1. The inclined surface 102 has an angle inclined towards the middle position of the box body 1. A groove with a "U"-shaped profile is formed in the middle position of the support portion 202. The position of the limiting block 103 corresponds to the position of the "U"-shaped profile groove in the middle of the support portion 202. The bracket 2 is a rectangular sheet structure made of plastic. Such a material selection can save cost investment. Four arc-shaped pieces 201 extend from the bottom side of the bracket 2. These four arc-shaped pieces 201 are respectively located on the four side lines of the rectangular profile of the bracket 2. Since the arc-shaped piece 201 has an inwardly inclined angle and the inclined surface 102 on the inner wall of the box body 1 also has an angle inclined towards the middle position of the box body 1, when the user needs to place the bracket 2 into the box body 1, the bracket 2 can be pressed into the box body 1 from top to bottom. During the downward pressing process of the bracket 2, the arc-shaped piece 201 and the inclined surface 102 are mutually extruded, and the two are assisted by the inclined surface 102 for guiding and limiting, thus ensuring that the bracket 2 will not be misaligned during the downward pressing process, improving the efficiency of the user in assembling the bracket 2. Further, since the position of the limiting block 103 corresponds to the position of the "U"-shaped profile groove in the middle of the support portion 202, when the user presses down the bracket 2, the limiting block 103 will slide in the "U"-shaped profile groove in the middle of the support portion 202, and the limiting of the bracket 2 is realized by means of the matching effect of the profiles between the two, ensuring that the bracket 2 will not shift in the box body 1 during the downward pressing and use processes, improving the stability of the bracket 2, making the reagent bottle 6 more stable and safe during transportation. Even further, since the middle position of the arc-shaped piece 201 has an inwardly concave arc profile, under the action of the arc profile, it is easier for the middle position of the arc-shaped piece 201 to deform under the action of external force. Such a setting makes it possible that if the reagent bottle 6 is impacted and knocked during transportation, at this time, the middle position of the arc-shaped piece 201 deforms, and while deforming, it buffers and absorbs the impact force and the knocking force, thereby improving the safety of the reagent bottle 6.

[0044] When culturing tumor organoids, the bracket 2 can be pulled upward to deform the limit plate and disengage it from the limit of the limit block 103. After the bracket 2 is taken out of the box body 1 and placed on the table, since both the support portion 202 and the limit portion 203 are curved arc structures and are arranged on both sides of the arc-shaped piece 201, when the user places the bracket 2 on the table, the support portion 202 and the limit portion 203 can simultaneously support and limit the bracket 2. The two can increase the contact area between the bottom of the bracket 2 and the table, thereby improving the overall stability of the bracket 2. Secondly, due to the inward inclination angle of the arc-shaped piece 201 and the arc contour of the limit portion 203, the arc-shaped piece 201, the limit portion 203 and the table form a triangular contour support system, thus effectively improving the structural stability of the bracket 2 after being placed on the table, so that the bracket 2 will not tip over or fall when the user picks up and places the reagent bottle 6; In summary, the cooperation of structures such as the arc-shaped piece 201, the support portion 202 and the limit portion 203 not only makes the bracket 2 more stable during transportation, but also can buffer and absorb the impact force and collision force generated during transportation, thereby improving the safety of the reagent bottle 6 during transportation. Moreover, the bracket 2 can be disassembled from the box body 1 and placed separately on the table, making it more convenient and efficient for the user to pick up and place the reagent bottle 6 during the tumor organoid culture process. In addition, the cooperation of the arc-shaped piece 201 and the support portion 202 makes the bracket 2 more stable when the user places it on the table, ensuring that the bracket 2 will not tip over or fall when the user picks up and places the reagent bottle 6, and improving the safety of the reagent bottle 6.

[0045] As an implementation manner in this embodiment, such as Figures 4 to 9As shown, the limiting assembly includes a storage barrel 3 and a first storage plate 4 fixedly connected to the bottom of the bracket 2, the bottom of the first storage plate 4 is fixedly connected to the second storage plate 402, and an extrusion block 5 is fixedly connected to the inner wall of the box body 1. The storage barrel 3 is a cylinder structure with a cylindrical profile, and a lightweight groove is opened on the storage barrel 3. The storage barrel 3 and the bracket 2 are an integral injection-molded structure. The position of the extrusion block 5 corresponds to the position of the storage barrel 3. The top of the extrusion block 5 is fixedly connected to an extrusion sheet 501, which is inserted into the lightweight groove. The middle position of the extrusion sheet 501 has an inwardly concave arc. In the limiting assembly, the reagent bottle 6 is mainly inserted into the lightweight groove through the storage barrel 3. The holder 2 is provided with a plurality of locking members 100, 102 and 104 locking members 106. The holder 2 is provided with a plurality of locking members 100, 104 and 104 locking members 107. The holder 2 is provided with a plurality of locking members 100, 102 and 104 locking members 108. The holder 2 is provided with a plurality of locking members 100, 104 and 104 locking members 106. The middle position of the squeezing sheet 501 has an inwardly concave arc, so the concave arc in the middle of the squeezing sheet 501 can squeeze the reagent bottle 6 in the storage barrel 3, thereby improving the firmness of the reagent bottle 6 in the storage barrel 3, so that the reagent bottle 6 will not sway in the storage barrel 3 during transportation. Since the squeezing block 5 is fixed to the bottom of the box body 1, when the bracket 2 is taken out of the box body 1, the squeezing sheet 501 will not continue to squeeze the reagent bottle 6 in the storage barrel 3, and the user will be more relaxed when taking and placing the reagent bottle 6. In summary, when the bracket 2 is placed in the box body 1, the storage barrel 3 can be squeezed with the squeezing block 5 in the box body 1. The pressing block 5 forms a structural fit, and the effect achieved by the fit makes the reagent bottle 6 more firm and stable in the storage barrel 3, thereby ensuring that the reagent bottle 6 will not sway or shake in the storage barrel 3 during transportation, thereby improving the safety of the reagent bottle 6. When the bracket 2 is taken out of the box body 1, the storage barrel 3 can only simply position the reagent bottle 6 without squeezing or limiting it, thereby making it easier and more convenient for the user to take and place the reagent bottle 6; since the storage barrel 3 and the bracket 2 are an integral injection-molded structure, during the production process, the storage rack and the bracket 2 are integrally injection-molded using the same mold, making the two easier to produce and manufacture, reducing capital investment.

[0046] Optionally, relevant information of the reagent bottle 6 is posted at the position of the storage tube 3 on the bracket 2, so that the user can refer to the information on the bracket 2 when taking or placing the reagent bottle 6, ensuring that the reagent bottle 6 will not be taken or placed incorrectly. Since the bracket 2 is made of plastic, the user can also choose to record relevant information of the reagent bottle 6 on the bracket 2 with a signature pen.

[0047] In this embodiment, if Figures 4 to 12 As shown, the size of the first storage plate 4 is larger than that of the second storage plate 402, the first storage plate 4, the second storage plate 402 and the bracket 2 are an integral injection-molded structure, the top of the first storage plate 4 is fixedly connected with a first positioning block 401, the bottom of the mark plate 7 is fixedly connected with an insert block 702, the middle position of the first positioning block 401 is provided with a groove body adapted to the contour of the insert block 702, the top of the second storage plate 402 is fixedly connected with a second positioning block 403, the overall contour of the second positioning block 403 is a sphere, and the top of the second positioning block 403 is an open segmented structure, in the limiting assembly, the mark plate 7 is mainly fixed by the first storage plate 4 and the second storage plate 402, and the bracket 2, the first storage plate 4 and the second storage plate 402 are fixed from top to bottom. The one-piece structure connected to each other below is integrally injection molded by a mold during actual production. Since the sizes of the first storage plate 4 and the mark plate 7 are consistent, the user can directly place the mark plate 7 on the top of the first storage plate 4 from top to bottom. Because a groove body adapted to the contour of the plug block 702 is provided at the middle position of the first positioning block 401, when the user places the mark plate 7 on the top of the first storage plate 4, the plug block 702 will be directly plugged into the groove body at the middle position of the first positioning block 401, and the mark plate 7 is limited and fixed with the help of the first positioning block 401. Optionally, a transparent plastic sealing sticker is used to seal the mark plate 7 at the position of the first storage plate 4 on the top of the bracket 2 to ensure that the mark plate 7 will not be contaminated by the external environment in the box body 1.

[0048] Before the operator carries out tumor organoid culture, he needs to determine the number of slats 701 on the mark plate 7 to be used, and then remove the excess slats 701 from the mark plate 7 and re-place them in a disposable sealed bag for storage. This operation has the following disadvantages: when the slats 701 are removed, they become messy and inconvenient to put into the sealed bag, and it is inconvenient to take and put them when they are used again. In addition, when the scattered slats 701 are carried in the box body 1, they will collide with each other due to shaking, which is not only easy to cause damage but also make noise; in the present application, when using After the user removes the mark plate 7 from the first storage plate 4, the user can place the extra slats 701 on the second storage plate 402. The second storage plate 402 is provided with a second positioning block 403. Since the overall contour of the second positioning block 403 is a sphere and the top of the second positioning block 403 is an open segmented structure, the top of the second positioning block 403 is elastic. When the user places the slats 701 on the second storage plate 402, the slats 701 can be inserted into the gap between two adjacent second positioning blocks 403 (such as Figure 12As shown in the figure, during the insertion process of the slat 701, the top of the second positioning block 403 will be squeezed, causing the top of the second positioning block 403 to deform and shrink inward. During the deformation process of the second positioning block 403, the slat 701 will be reversely squeezed, thereby achieving the fixing effect of the slat 701. Further, when the specimen plate 7 is used up, it can be re-placed on the top of the first storage plate 4. Since the gap between the first storage plate 4 and the second storage plate 402 is greater than the height of the slat 701, placing the slat 701 on the second storage plate 402 will not affect the storage of the specimen plate 7. After both are placed, they can be re-sealed with the transparent plastic sealing sticker on the top of the bracket 2. When using the specimen plate 7 and the slat 701 next time, they can be directly taken from the first storage plate 4 and the second storage plate 402. And under the limiting action of the second positioning block 403, the slats 701 will not collide with each other, and it is convenient and efficient to take the slats 701; In summary, by setting the first storage plate 4 and the second storage plate 402, the specimen plate 7 and the slats 701 can be respectively limited and fixed. On the one hand, this improves the efficiency of the user in taking and placing the specimen plate 7 and the slats 701. On the other hand, it effectively ensures the safety and convenience of the specimen plate 7 and the slats 701 during the secondary use process, thereby making the entire tumor organ culture process operation more concise and efficient.

[0049] The working principle of the technical solution provided by the present invention is as follows:

[0050] When the user needs to perform tumor organoid culture operations, open the lid 101 on the top of the box body 1, and then pull the bracket 2 upward to deform the limit plate and disengage it from the limit of the limit block 103. After the bracket 2 is taken out of the box body 1, place it on the table. Since both the support part 202 and the limit part 203 are curved arc structures and are arranged on both sides of the arc-shaped piece 201, when the user places the bracket 2 on the table, the support part 202 and the limit part 203 can simultaneously support and limit the bracket 2, and the two can increase the contact area between the bottom of the bracket 2 and the table, thereby improving the overall stability of the bracket 2. Secondly, due to the inwardly inclined angle of the arc-shaped piece 201 and the arc-shaped contour of the limit part 203, the arc-shaped piece 201, the limit part 203 and the table form a triangular contour support system, which effectively improves the structural stability of the bracket 2 after it is placed on the table, so that the bracket 2 will not tip over or fall when the user picks up or places the reagent bottle 6. It is worth mentioning that since the position of the extrusion block 5 corresponds to the position of the placement cylinder 3, when the bracket 2 is in the box body 1, the placement cylinder 3 is just located on the top of the extrusion block 5. Also, since a lightening groove is opened on the placement cylinder 3 and the extrusion piece 501 is inserted into the lightening groove, and the middle position of the extrusion piece 501 has an inwardly concave arc, the inwardly concave arc of the middle of the extrusion piece 501 can squeeze the reagent bottle 6 in the placement cylinder 3, thereby improving the firmness of the reagent bottle 6 in the placement cylinder 3, so that the reagent bottle 6 will not swing in the placement cylinder 3 during transportation. Since the extrusion block 5 is fixed to the bottom of the box body 1, when the bracket 2 is taken out of the box body 1, the extrusion piece 501 will not continue to squeeze the reagent bottle 6 in the placement cylinder 3. At this time, it will be easier for the user to pick up and place the reagent bottle 6.

[0051] When the user needs to use the scale plate 7, the user tears off one end of the transparent plastic sealing sticker at the top of the first storage plate 4 and then takes out the scale plate 7 from the first storage plate 4 from bottom to top. After the user removes the scale plate 7 from the first storage plate 4, the redundant slats 701 are placed on the second storage plate 402. Since the overall contour of the second positioning block 403 is spherical and the top of the second positioning block 403 is an open segmented structure, the top of the second positioning block 403 has elasticity. When the user places the slats 701 on the second storage plate 402, the slats 701 can be inserted into the gap between two adjacent second positioning blocks 403. During the insertion process of the slats 701, the top of the second positioning block 403 will be squeezed, causing the top of the second positioning block 403 to deform and shrink inward. During the deformation of the second positioning block 403, the slats 701 will be reversely squeezed, thus achieving the fixing effect on the slats 701. When the scale plate 7 is used up, it can be placed back on the top of the first storage plate 4. Since a groove adapted to the contour of the insertion block 702 is provided at the middle position of the first positioning block 401, when the user places the scale plate 7 on the top of the first storage plate 4, the insertion block 702 will be directly inserted into the groove at the middle position of the first positioning block 401, and the scale plate 7 will be limited and fixed by the first positioning block 401. Since the gap between the first storage plate 4 and the second storage plate 402 is greater than the height of the slats 701, placing the slats 701 on the second storage plate 402 will not affect the storage of the scale plate 7. After both are placed, they can be sealed again with the transparent plastic sealing sticker on the top of the bracket 2. When using the scale plate 7 and the slats 701 next time, they can be directly taken from the first storage plate 4 and the second storage plate 402. And under the limiting effect of the second positioning block 403, the slats 701 will not collide with each other, and it is convenient and efficient to take the slats 701.

[0052] The present invention covers any substitutions, modifications, equivalent methods, and solutions made to the essence and scope of the present invention. For the public to have a thorough understanding of the present invention, specific details are described in detail in the following preferred embodiments of the present invention. However, those skilled in the art can fully understand the present invention without these detailed descriptions. Additionally, to avoid unnecessary confusion to the essence of the present invention, well-known methods, processes, procedures, components, and circuits are not described in detail.

[0053] The above are only the preferred embodiments of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the principle of the present invention, several improvements and refinements can be made, and these improvements and refinements should also be regarded as the protection scope of the present invention.

Claims

1. A tumor organoid culture kit, comprising a box body, characterized in that, One side of the box body is rotatably connected with a box cover. A bracket is inserted into the box body. A reagent bottle and a label board are placed on the bracket, and strip plates are inserted into the label board. A limiting component is used to limit the reagent bottle and the label board, and the limiting component is respectively connected with the bracket and the box body. The limiting component includes a storage cylinder and a first storage board fixedly connected to the bottom of the bracket. A second storage board is fixedly connected to the bottom of the first storage board. An extrusion block is fixedly connected to the inner wall of the box body. The position of the extrusion block corresponds to the position of the storage cylinder. An extrusion sheet is fixedly connected to the top of the extrusion block. A lightening slot is formed in the storage cylinder, and the extrusion sheet is inserted into the lightening slot. The middle position of the extrusion sheet has an inwardly concave arc. A first positioning block is fixedly connected to the top of the first storage board. An insertion block is fixedly connected to the bottom of the label board. A slot body adapted to the contour of the insertion block is formed at the middle position of the first positioning block. A second positioning block is fixedly connected to the top of the second storage board. The overall contour of the second positioning block is spherical, and the top of the second positioning block is an open segmented structure. An arc-shaped sheet is fixedly connected to the bottom of the bracket. One end of the arc-shaped sheet is fixedly connected with a support portion, and a limiting portion is fixed to the outer wall of the bottom of the arc-shaped sheet. The arc-shaped sheet has an inwardly inclined angle, and the middle position of the arc-shaped sheet has an inwardly concave arc contour. Both the support portion and the limiting portion are curved arc structures. An inclined surface and a limiting block are fixedly connected to the inner wall of the box body. The inclined surface has an angle inclined towards the middle position of the box body. A slot body with a "U"-shaped contour is formed at the middle position of the support portion. The position of the limiting block corresponds to the position of the "U"-shaped contour slot body at the middle of the support portion.

2. The tumor organoid culture kit according to claim 1, wherein The storage cylinder is a cylindrical profile barrel structure, and the storage cylinder and the bracket are of an integrally injection-molded structure.

3. The tumor organoid culture kit according to claim 1, wherein The size of the first storage board is larger than that of the second storage board. The first storage board, the second storage board and the bracket are of an integrally injection-molded structure.

Citation Information

Patent Citations

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