Optical measurement system of full-automatic POCT (Point of Care Testing) high-precision immunity analyzer

Abstract

The invention discloses an optical measurement system of a full-automatic POCT high-precision immunity analyzer, the optical measurement system comprises a reaction bin part, an optical measurement part and a substrate separate injection part, the reaction bin part comprises an incubation assembly, the incubation assembly comprises an incubation table and a side detection convex clamping seat, and a reaction cup comprises a reaction cup upper cup sleeve; the optical detection component is used for performing optical detection on contents in the reaction cup and comprises a light receiving detection assembly, and the light receiving detection assembly comprises a side detection light receiving seat; the substrate separate injection part is used for injecting substrate liquid into the reaction cup and comprises an injection head; when light emitting detection is carried out, the side detection light receiving seat and the side detection convex clamping seat are embedded to form a first multi-concave-convex-ring embedded structure, the filling head and the upper cup sleeve of the reaction cup are embedded to form a second multi-concave-convex-ring embedded structure, and the first multi-concave-convex-ring embedded structure and the second multi-concave-convex-ring embedded structure form a plurality of light closing matching surfaces. The chemiluminescence reaction in the reaction cup is carried out in a stable and reliable closed environment, the interference of an external light source is reduced, and the detection specificity and sensitivity are improved.

Description

Technical Field

[0001] The invention relates to the technical field of clinical detection medical treatment, and in particular to an optical measurement system of a fully automatic POCT high-precision immunoassay analyzer. Background Art

[0002] At present, the fully automatic POCT high-precision immunoassay is a widely used device in clinical diagnosis and medical testing. It performs highly sensitive immunoassay based on the principle of chemiluminescence. Chemiluminescence immunoassay is a technology that uses light signals generated by chemical reactions to detect specific biomarkers. In this analysis, the sample reacts with antibodies or antigens marked with luminescent markers to generate light signals, and the intensity of the light signals is measured to quantitatively analyze specific components in the sample.

[0003] Therefore, ensuring that the luminescence in the test cuvette is not interfered by external light sources is the key to ensuring the accuracy of the test results.

[0004] The existing chemiluminescence immunoassay analyzers have unreasonable photometric layouts, often with problems such as complex structure, poor shading effect, and high assembly precision requirements. They are easily disturbed by external light and it is difficult to achieve efficient shading effect, resulting in external stray light having a greater impact on the test results, reducing the accuracy and reliability of the test.

[0005] Therefore, it is necessary to provide a light monitoring system for a fully automatic immunoassay analyzer, so as to effectively prevent external light from entering the detection system and affecting the detection results. Summary of the invention

[0006] The purpose of the present application is to overcome the problems in the prior art that the photometric system of the chemiluminescence immunoassay analyzer has a complex structure, poor shading effect, and is easily disturbed by external light, resulting in a significant impact of stray light on the test results, thereby reducing the accuracy and reliability of the test. Thus, an optical measurement system for a fully automatic POCT high-precision immunoassay analyzer with a simple structure and efficient shading effect is provided. The optical measurement system has a simple structure and can enable the chemiluminescence reaction in the reaction cup to be carried out in a stable and reliable closed environment, significantly reducing the interference of external light sources and improving the specificity and sensitivity of the test.

[0007] In order to achieve the above object, the present invention provides an optical measurement system for a fully automatic POCT high-precision immunoassay analyzer, the optical measurement system comprising: A reaction chamber component, wherein the reaction chamber component comprises an incubation component, the incubation component comprises an incubation table and a side inspection convex seat, the incubation table comprises a reaction cup placement area, and a first light through hole arranged on the side of the reaction cup placement area, the reaction cup placement area is used to place the reaction cup, the side inspection convex seat is arranged on a side of the first light through hole away from the reaction cup placement area, and the reaction cup comprises a reaction cup upper cup sleeve; An optical detection component, which is used to perform optical detection on the content of the reaction cup, and includes a light receiving detection component, and the light receiving detection component includes a side light receiving seat; A substrate dispensing component, which is used to add substrate liquid into the reaction cup and includes a filling head; When performing luminescence detection, the side inspection light receiving seat and the side inspection convex holder are embedded in each other to form a first multiple concave-convex ring embedded structure, and the filling head is embedded in the cup sleeve on the reaction cup to form a second multiple concave-convex ring embedded structure.

[0008] Furthermore, an annular groove is provided at the front end of the side inspection light receiving seat, and the side inspection convex card seat is a convex circular ring, and the side inspection convex card seat and the annular groove are embedded in each other to form the first multiple concave-convex ring embedded structure, and the first multiple concave-convex ring embedded structure includes a first light-shielding mating surface, and a second annular light-shielding buffer zone and a third annular light-shielding buffer zone, wherein the first light-shielding mating surface is the fitting surface between the side inspection convex card seat and the side inspection light receiving seat.

[0009] Furthermore, the light receiving detection component also includes a photomultiplier tube, and the photomultiplier tube is arranged on a side of the side inspection light receiving seat away from the side inspection convex seat.

[0010] Furthermore, two circles of annular pits are provided at the bottom of the filling head, and a convex edge is provided on the edge of the cup sleeve on the reaction cup, and the cup sleeve on the reaction cup is embedded with the two circles of annular pits to form the second multiple concave-convex ring embedded structure; the second multiple concave-convex ring embedded structure includes a second light-shielding mating surface, and a fourth annular light-shielding buffer zone, a fifth annular light-shielding buffer zone and a sixth annular light-shielding buffer zone, wherein the second light-shielding mating surface is the fitting surface between the cup sleeve on the reaction cup and the filling head.

[0011] Furthermore, the reaction chamber component also includes a reaction chamber drive assembly, which includes a stepper motor, a slider and a linear guide rail. The incubation assembly is connected to the slider, and the stepper motor drives the slider to move forward and backward on the linear guide rail to drive the incubation assembly to move in the forward and backward directions.

[0012] Furthermore, the optical measurement component also includes a first optical detection drive component, and the first optical detection drive component includes a rotating electromagnet. The rotating electromagnet drives the first eccentric wheel to swing, thereby driving the light shielding plate to swing. The light shielding plate is a fan-shaped structure with a circular hole on one side for aligning with the detection hole of the photomultiplier tube.

[0013] Furthermore, the optical detection component further comprises an optical detection second drive assembly, and the optical detection second drive assembly comprises an optical detection drive motor, and the optical detection drive motor can drive the side detection receiving optical seat to move so as to be close to the side detection convex card seat; The optical inspection drive motor can drive the second eccentric wheel to rotate. The optical inspection drive motor converts the rotational motion into linear motion through the deep groove ball bearing and the waist-shaped slot hole of the optical inspection moving block. The maximum stroke of the motion is twice the eccentricity of the second eccentric wheel.

[0014] Furthermore, the side inspection convex holder and the incubation table are fixed into one body by screws.

[0015] Furthermore, the incubation platform also includes a reagent placement area, and the reagent placement area is used to place the reagent strip; Furthermore, a heating rod assembly is provided at the lower end of the incubation table, and the heating rod assembly includes a heating rod, a temperature sensor and an overheating protector. The incubation table is connected to the incubation installation base plate through an insulating support column, and the insulating support column is made of non-metallic insulating material. The incubation table is wrapped with insulation cotton.

[0016] Furthermore, the reagent strip is made of black light-proof material, and is provided with a plurality of slots, which are respectively used to hold substrate, reagent, cleaning solution, diluent, and magnetic separation liquid.

[0017] Furthermore, the reaction cup is a combination of black and transparent.

[0018] Furthermore, the reaction cup and the reagent strip are an integrally formed structure, and the cup sleeve on the reaction cup and the slot of the reagent strip are an integral structure.

[0019] Furthermore, the cup sleeve on the reaction cup has an opening, and the opening is used for docking with the reagent strip, and the docking is a light interference fit with a tapered surface.

[0020] Furthermore, the incubation component also includes a static liquid drainage seat, which is black and has a circular boss disposed thereon, and the circular boss is engaged with the annular groove at the front end of the side inspection light receiving seat.

[0021] The present invention also provides a fully automatic POCT high-precision immunoassay analyzer, which includes the above-mentioned optical measurement system.

[0022] Compared with the prior art, the present invention has the following beneficial effects: The optical measurement system of the fully automatic POCT high-precision immunoassay instrument provided by the present invention, when performing luminescence detection, the side detection convex card seat arranged at the first light through hole on one side of the reaction cup placement area is embedded with the annular groove at the front end of the side detection light receiving seat in the optical measurement component to form a first multiple concave-convex ring embedded structure, and the reaction cup filling head used to fill the substrate liquid into the reaction cup is embedded with the cup sleeve on the reaction cup to form a second multiple concave-convex ring embedded structure. The first and second multiple concave-convex ring embedded structures form multiple closed light matching surfaces, so that the chemiluminescent reaction in the reaction cup is carried out in a stable and reliable closed environment, with an efficient light shielding effect, significantly reducing the interference of external light sources, and improving the specificity and sensitivity of detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0024] Figure 1 It is a structural schematic diagram of the optical measurement system of the present invention; Figure 2 This is a schematic diagram of the structure of the optical measurement system reagent strip of the present invention; Figure 3 The first multiple concave-convex ring embedded structure of the optical measurement system of the present invention; Figure 4 The second multiple concave-convex ring embedded structure of the optical measurement system of the present invention; Figure 5 A reaction chamber driving component of the optical measurement system of the present invention; Figure 6 The first optical detection driving component of the optical detection system of the present invention; Figure 7 The optical detection second driving component of the optical detection system of the present invention; Figure 8 It is a schematic diagram of the structure of the incubation component of the optical measurement system of the present invention; Fig. 9 is a front view of an incubation component of the optical detection system of the present invention; Fig.10 It is a schematic diagram of the joint portion between the static liquid drainage seat and the side inspection light receiving seat of the incubation component of the present invention.

[0025] Reference numerals: Incubation table 11, reaction cup 111, reagent strip 112, reaction solution luminous area 113, reaction cup cover 1111, side inspection convex card seat 12, first light through hole 13; Instrument bottom plate 10, left side plate 101, right side plate 102, stepping motor 14, linear rail slider 15, linear guide rail 16, incubation moving bottom plate 170, incubation moving left side plate 171, incubation moving right side plate 172, synchronous belt 18; Side inspection light receiving seat 21, photon detection channel 211, photomultiplier tube 22; Rotating electromagnet 231, first eccentric wheel 232, light shielding sheet 233, circular hole 234; Optical inspection drive motor 241, second eccentric wheel 242, deep groove ball bearing 243, optical inspection moving block 244; The first light-shielding matching surface 121, the first annular light-shielding buffer area 122, the second annular light-shielding buffer area 123; the second light-shielding matching surface 311, the third annular light-shielding buffer area 312, the fourth annular light-shielding buffer area 313, the fifth annular light-shielding buffer area 314; Filling head 31, dispensing mounting seat 32; Drain seat 41 , circular boss 411 , drain pipe joint 42 , heating rod assembly 51 , heat insulation support column 52 , incubation installation base plate 53 . DETAILED DESCRIPTION

[0026] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in the field without creative work are within the scope of protection of the present invention.

[0027] Exemplary embodiments will be described in detail herein, examples of which are shown in the accompanying drawings. When the following description refers to the drawings, the same numbers in different drawings represent the same or similar elements unless otherwise indicated. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present disclosure. Instead, they are merely examples of devices and methods consistent with some aspects of the present disclosure as detailed in the appended claims.

[0028] like Figure 1-4 As shown, an embodiment of the present invention provides an optical measurement system of a fully automatic POCT high-precision immunoassay analyzer, comprising: A reaction chamber component, the reaction chamber component includes an incubation component, the incubation component includes an incubation table 11 and a side inspection convex seat 12, the incubation table 11 includes a reaction cup placement area, the reaction cup placement area is used to place a reaction cup 111, the reaction cup includes a reaction cup upper cup sleeve 1111, the incubation table 11 also includes a first light through hole 13 arranged on the side of the reaction cup placement area, the side inspection convex seat 12 is arranged on the side of the first light through hole 13 away from the reaction cup placement area, the incubation table 11 also includes a reagent placement area, the reagent placement area is used to place a reagent strip 112; an optical measurement component, the optical measurement component is used to perform optical detection on the content of the reaction cup 111, and it includes a light receiving detection component, and the light receiving detection component includes a side inspection light receiving seat 21; a substrate dispensing component, the substrate dispensing component is used to add substrate liquid into the reaction cup 111, and it includes a filling head 31 and a dispensing mounting seat 32.

[0029] The side inspection light receiving seat 21 has a photon detection channel 211 inside, and a ring groove is provided at the front end thereof, that is, the end close to the side inspection convex card seat 12; the side inspection convex card seat 12 is in a convex ring shape. The light receiving detection component also includes a photomultiplier tube, which is arranged on the side of the side inspection light receiving seat 21 away from the side inspection convex card seat 12.

[0030] First, when a chemical reaction occurs, the light emitted by the liquid in the reaction cup 111 enters the photon detection channel 211 through the first light through hole 13, and finally enters the photomultiplier tube 22 for detection. Therefore, there may be contamination from external light sources at the junction of the side inspection convex card seat 12 and the side inspection light receiving seat 21.

[0031] The first multiple concave-convex ring embedding structure formed by the side inspection convex card seat 12 and the annular groove of the side inspection light receiving seat 21 described in this embodiment is as follows: Figure 3 As shown, the fitting surface between the side inspection convex card seat 12 and the side inspection light receiving seat 21 is the first light shielding mating surface 121, which is the main light shielding surface. The first light shielding mating surface 121 has a low roughness and no gaps, and can block most of the external light sources. However, due to the limited processing accuracy, the first light shielding mating surface 121 cannot reach the theoretical smooth plane. From a microscopic point of view, the first light shielding mating surface 121 still has many small uneven places. At this time, the external light source may diffract or reflect a small amount of light source into the photon detection channel 211 when passing through these pits or bosses.

[0032] In view of the above problems, the first multiple concave-convex ring embedded structure described in this embodiment also has a first annular light-shielding buffer zone 122 and a second annular light-shielding buffer zone 123, that is, a small amount of light source diffracted or reflected from the first light-shielding mating surface 121 will enter the first and second annular light-shielding buffer zones 122 and 123. The first and second annular light-shielding buffer zones 122 and 123 are both narrow and long annular channels. When a small amount of light source diffracted or reflected from the first light-shielding mating surface 121 enters the annular channels of the first and second annular light-shielding buffer zones 122 and 123, a small amount of light source will undergo multiple reflections in the two annular channels, thereby exhausting the photon energy. Therefore, the number of photons that actually pass through the first and second annular light-shielding buffer zones 122 and 123 will be very small, thereby achieving a relatively ideal light-shielding effect, avoiding external light sources from entering the photon detection channel 211, and reducing the impact on the detection results.

[0033] On the other hand, when a chemical reaction occurs, there will also be contamination from external light sources at the connection between the filling head 31 and the cup sleeve 111 on the reaction cup.

[0034] Furthermore, in this embodiment, a second multiple concave-convex ring interlocking structure is provided at the connection between the filling head 31 and the cup sleeve 111 of the reaction cup to avoid the problem of external light source pollution at the connection.

[0035] Specifically, Figure 4 As shown, the bottom of the filling head 31 is provided with two circles of annular pits, and the edge of the cup sleeve 111 on the reaction cup is provided with a convex edge. When a chemical reaction occurs, the edge of the cup sleeve 111 on the reaction cup is embedded with the two circles of annular pits at the bottom of the filling head 31 to form a second multiple concave and convex ring embedded structure. Among them, the fitting surface between the cup sleeve 111 on the reaction cup and the bottom of the filling head 31 is the second light shielding matching surface 311, which is the main light shielding surface. Similarly, based on the limited processing accuracy, in order to prevent the external light source from diffracting or reflecting a small amount of light source into the reaction liquid luminous area 113 when passing through the pit or boss at the second light-shielding matching surface 311, thereby affecting the detection result, the second multiple concave-convex ring embedded structure also includes a third annular light-shielding buffer zone 312, a fourth annular light-shielding buffer zone 313, and a fifth annular light-shielding buffer zone 314. The third, fourth and fifth annular light-shielding buffer zones 312, 313 and 314 are all narrow and long annular channels. When a small amount of light source diffracted or reflected from the second light-shielding matching surface 311 enters the annular channels of the third, fourth and fifth annular light-shielding buffer zones 312, 313 and 314, the small amount of light source will undergo multiple reflections in the three annular channels, thereby exhausting the photon energy. Therefore, the number of photons that actually pass through the third, fourth and fifth annular light-shielding buffer zones 312, 313 and 314 will be very small, thereby achieving a more ideal light-shielding effect and reducing the pollution of external light sources.

[0036] It can be seen from the above that the first and second multiple concave-convex ring embedded structures described in this embodiment form multiple light-blocking matching surfaces, so that the chemiluminescence reaction in the reaction cup 111 is carried out in a stable and reliable closed environment, with efficient light-shielding effect, significantly reducing the interference of external light sources, and improving the specificity and sensitivity of detection.

[0037] In the optical measurement system of the fully automatic POCT high-precision immunoassay analyzer described in this embodiment, the reaction chamber component also includes a reaction chamber drive component, which is mainly used to move the incubation component in the front-to-back direction and cooperate with the syringe pump to realize the transfer of the liquid in the reagent strip 112. The reaction chamber drive component includes a stepper motor 14, a linear rail slider 15 and a linear guide rail 16, such as Figure 5 As shown, the reaction chamber driving assembly is arranged on the instrument base plate 10, and linear guide rails 16 are installed on the left plate 101 and the right plate 102 respectively; the linear rail slider 15 is connected to the incubation assembly through the incubation movable base plate 170, the incubation movable left plate 171, and the incubation movable right plate 172; the stepper motor 14 drives the linear rail slider 15 to slide on the linear guide rail 16 through the synchronous belt 18, thereby realizing the movement of the incubation assembly in the front and rear directions.

[0038] In the optical measurement system of the fully automatic POCT high-precision immunoassay analyzer described in this embodiment, the optical measurement component also includes an optical detection first drive component and an optical detection second drive component.

[0039] The first optical detection drive assembly includes a rotating electromagnet 231, which drives the first eccentric wheel 232 to swing, thereby driving the shading plate 233 to swing. The shading plate 233 is a fan-shaped structure with a circular hole 234 on one side for aligning with the detection hole of the photomultiplier tube 22. Figure 6 is the internal structure diagram of the first drive component when it is not detected. Figure 6 It can be seen that photon detection is not performed at this time, and the circular hole 234 on the shading sheet 233 is misaligned with the detection hole of the light detection and light receiving seat 21. At this time, light cannot enter the photomultiplier tube 22; when photon detection is performed, the rotating electromagnet 231 drives the first eccentric wheel 232 to swing, thereby driving the shading sheet 233 to swing, and the circular hole 234 on the shading sheet 233 is aligned with the detection hole of the light detection and light receiving seat 21. At this time, light can enter the photomultiplier tube 22 for detection.

[0040] like Figure 7As shown, the optical inspection second drive assembly includes an optical inspection drive motor 241, and the optical inspection drive motor 241 can drive the side inspection light receiving seat 21 to move to be close to the side inspection convex card seat 12, so as to perform photon detection. There are a total of six photon detection channels in this embodiment. Before performing photon detection of the second to sixth channels, the side inspection light receiving seat 21 needs to be retracted first and then extended to be close to the side inspection convex card seat 12 to perform photon detection of the second to sixth channels in sequence. This recovery process is driven by the optical inspection drive motor 241 to drive the second eccentric wheel 242 to rotate, and then the rotational motion is converted into linear motion through the deep groove ball bearing 243 and the waist-shaped slot hole of the optical inspection moving block 244. The maximum stroke of the motion is twice the eccentricity of the second eccentric wheel 242.

[0041] In some embodiments, the side inspection convex holder 12 and the incubation table 11 are fixed together by screws, which enhances the stability of the structure and simplifies the assembly process of the device.

[0042] In some embodiments, Figure 8 and 9 As shown, the upper end of the incubation table 11 is provided with a pit corresponding to the reagent strip 112, and the lower end is provided with two heating rod assemblies 51, which are used to heat the incubation table 11, so that the reagent strip 112 in the incubation table 11 and the liquid in the reaction cup 111 are heated and kept warm, and the liquid in the reagent strip 112 is accurately controlled at 37°C. The heating rod assembly 51 includes two heating rods, a temperature sensor, and an overheating protector. In order to prevent the heat of the heating rod assembly 51 from being transferred to other non-essential temperature control parts, the incubation table 11 is designed to be connected to the incubation installation base plate 53 through an insulating support column 52, and the insulating support column 52 is made of non-metallic insulating material; in addition, the incubation table 11 will be wrapped with a layer of insulation cotton on all sides to reduce energy loss and facilitate precise temperature control.

[0043] In some embodiments, the reagent strip 112 is made of black light-proof material, and a plurality of slots are provided on the reagent strip 112, and the plurality of slots are used to hold substrates, reagents, cleaning solutions, diluents, and magnetic separation liquids, respectively.

[0044] The reaction cup 111 is a container for loading samples and reagents, and is used in conjunction with the reagent strip 112. In this embodiment, the reaction cup 111 and the reagent strip 112 are an integrally formed structure.

[0045] In some embodiments, the reaction cup 111 is designed to be a combination of black and transparent. Specifically, the portion of the reaction cup 111 corresponding to the first optical through hole 13 is designed to be transparent, which can ensure that the light emitted by the reaction liquid in the reaction cup 111 directly enters the first optical through hole 13, reducing the scattering and reflection of the light inside the reaction cup 111, thereby improving the collection efficiency of the light signal; the rest of the reaction cup 111 is black, and the black portion absorbs light, reducing the stray light reflected or scattered from the outer wall of the reaction cup 111 from entering the first optical through hole 13, which can reduce background noise and improve the signal-to-noise ratio of the detection. The reaction cup 111 also includes a cup sleeve 1111 on the reaction cup, which is used to prevent light leakage from the gap at the loading joint of the reagent strip 112 and the incubation table 11. In this embodiment, the cup sleeve on the reaction cup and the slot of the reagent strip are an integral structure.

[0046] In some embodiments, the cup sleeve 1111 on the reaction cup has an opening, and the opening is used for docking with the reagent strip 112, and the docking is a light interference fit with a tapered surface. It should be supplemented that: the light interference fit with a tapered surface is a type of fit, where the "tapered surface" refers to the taper geometry of the opening of the cup sleeve 1111 on the reaction cup and the mating interface of the reagent strip 112. There are processing errors, and the tapered surface must be used to compensate for the processing errors. In addition, the manufacturing of the mold also requires a certain tapered surface as a draft angle; "light interference" means that the gap between the mating parts is very small, but not completely tightened, allowing a certain amount of room for movement, while ensuring the stability and sealing of the connection.

[0047] In some embodiments, Fig.10 As shown, the incubation component also includes a static drain seat 41, which is used to empty the empty space and possible impurities in the pipeline before filling the substrate. The static drain seat 41 is black, and a circular boss 411 is provided on the static drain seat 41. The static drain seat 41 is used to empty the empty space and possible impurities in the pipeline before filling the substrate, and when the optical inspection and receiving light seat 21 returns to zero position during shutdown, it just rests on the circular boss 411 of the static drain seat 41, and the circular boss 411 is engaged with the annular groove at the front end of the side inspection and receiving light seat 21, so as to prevent the photomultiplier tube from aging due to external environmental light and affect product performance.

[0048] In a second aspect, an embodiment of the present invention further provides a fully automatic POCT high-precision immunoassay analyzer, including the optical measurement system as described above.

[0049] The preferred embodiments of the present application are described in detail above, but the present application is not limited thereto. Within the technical concept of the present application, the technical solution of the present application can be subjected to a variety of simple modifications, including combining various technical features in any other suitable manner, and these simple modifications and combinations should also be regarded as the contents disclosed in the present application and belong to the protection scope of the present application.

Claims

1. An optical measurement system for a fully automatic POCT high-precision immunoassay analyzer, characterized in that: include A reaction chamber component, wherein the reaction chamber component comprises an incubation component, the incubation component comprises an incubation table and a side inspection convex seat, the incubation table comprises a reaction cup placement area, and a first light through hole arranged on the side of the reaction cup placement area, the reaction cup placement area is used to place the reaction cup, the side inspection convex seat is arranged on a side of the first light through hole away from the reaction cup placement area, and the reaction cup comprises a reaction cup upper cup sleeve; An optical detection component, which is used to perform optical detection on the content of the reaction cup, and includes a light receiving detection component, and the light receiving detection component includes a side light receiving seat; A substrate dispensing component, which is used to add substrate liquid into the reaction cup and includes a filling head; When performing luminescence detection, the side inspection light receiving seat and the side inspection convex holder are embedded in each other to form a first multiple concave-convex ring embedded structure, and the filling head is embedded in the cup sleeve on the reaction cup to form a second multiple concave-convex ring embedded structure.

2. The optical measurement system according to claim 1, characterized in that: An annular groove is provided at the front end of the side inspection light receiving seat, and the side inspection convex card seat is a convex circular ring. The side inspection convex card seat and the annular groove are embedded in each other to form the first multiple concave-convex ring embedded structure, and the first multiple concave-convex ring embedded structure includes a first light-shielding mating surface, and a second annular light-shielding buffer zone and a third annular light-shielding buffer zone, wherein the first light-shielding mating surface is the fitting surface between the side inspection convex card seat and the side inspection light receiving seat.

3. The optical measurement system according to claim 2, characterized in that: The light receiving detection component also includes a photomultiplier tube, which is arranged on a side of the side inspection light receiving seat away from the side inspection convex seat.

4. The optical measurement system according to claim 1, characterized in that: Two circles of annular pits are provided at the bottom of the filling head, and a convex edge is provided on the edge of the cup sleeve on the reaction cup. The cup sleeve on the reaction cup is embedded with the two circles of annular pits to form the second multiple concave-convex ring embedded structure; the second multiple concave-convex ring embedded structure includes a second light-shielding matching surface, and a fourth annular light-shielding buffer zone, a fifth annular light-shielding buffer zone and a sixth annular light-shielding buffer zone, wherein the second light-shielding matching surface is the fitting surface between the cup sleeve on the reaction cup and the filling head.

5. The optical measurement system according to claim 1, characterized in that: The reaction chamber component also includes a reaction chamber drive assembly, which includes a stepper motor, a slider and a linear guide rail. The incubation assembly is connected to the slider, and the stepper motor drives the slider to move forward and backward on the linear guide rail to drive the incubation assembly to move in the forward and backward directions.

6. The optical measurement system according to claim 1, characterized in that: The optical measurement component also includes a first optical detection drive component, which includes a rotating electromagnet. The rotating electromagnet drives the first eccentric wheel to swing, thereby driving the light shielding plate to swing. The light shielding plate is a fan-shaped structure with a circular hole on one side for aligning with the detection hole of the photomultiplier tube.

7. The optical measurement system according to claim 1, characterized in that: The optical detection component further includes an optical detection second drive assembly, and the optical detection second drive assembly includes an optical detection drive motor, and the optical detection drive motor can drive the side detection receiving optical seat to move so as to be close to the side detection convex card seat; The optical inspection drive motor can drive the second eccentric wheel to rotate. The optical inspection drive motor converts the rotational motion into linear motion through the deep groove ball bearing and the waist-shaped slot hole of the optical inspection moving block. The maximum stroke of the motion is twice the eccentricity of the second eccentric wheel.

8. The optical measurement system according to claim 1, characterized in that: The side inspection convex clamping seat and the incubation platform are fixed into one body by screws.

9. The optical measurement system according to claim 1, characterized in that: The incubation station also includes a reagent placement area, and the reagent placement area is used to place a reagent strip.

10. The optical measurement system according to claim 1, characterized in that: A heating rod assembly is provided at the lower end of the incubation table, and the heating rod assembly includes a heating rod, a temperature sensor and an overheating protector. The incubation table is connected to the incubation installation base plate through an insulating support column, and the insulating support column is made of non-metallic insulating material. The incubation table is wrapped with insulation cotton.

11. The optical measurement system according to claim 9, characterized in that: The reagent strip is made of black light-proof material and is provided with a plurality of slots, which are respectively used to hold substrate, reagent, cleaning solution, diluent, and magnetic separation liquid.

12. The optical measurement system according to claim 1, characterized in that: The reaction cup is a combination of black and transparent.

13. The optical measurement system according to claim 1, characterized in that: The reaction cup and the reagent strip are an integrally formed structure, and the cup sleeve on the reaction cup and the slot of the reagent strip are an integral structure.

14. The optical measurement system according to claim 1, characterized in that: The cup sleeve on the reaction cup has an opening, and the opening is used for docking with the reagent strip, and the docking is a light interference fit with a tapered surface.

15. The optical measurement system according to claim 1, characterized in that: The incubation component also includes a static liquid drainage seat, which is black and has a circular boss disposed thereon. The circular boss is engaged with the annular groove at the front end of the side inspection light receiving seat.

16. A fully automatic POCT high-precision immunoassay analyzer, characterized in that: Comprising the optical measurement system as described in any one of claims 1-15.

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