Valve frame and artificial valve device

Abstract

This application relates to a valve frame and an artificial valve device. The main frame segment has an internal space, a distal opening, and a proximal opening. The upper coronary frame segment is connected to the distal end of the main frame segment and is an annular frame with an internal space. This internal space communicates with the internal space of the main frame through the distal opening. The anchoring frame segment is connected to the proximal end of the main frame segment, and its axial length is greater than that of the main frame segment. The anchoring frame segment has an axially elongated structure within the overall valve frame structure. Compared to the anchoring frame segment, the main frame segment has a shorter axial length, allowing it to be positioned relatively high, close to the upper side of the original valve annulus, after the valve frame is implanted into the left atrium and left ventricle. Furthermore, the perforated structure design on the main frame segment aligns with the sutured bovine pericardium, effectively preventing the risk of left ventricular outflow tract obstruction.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and in particular to valve stents and artificial valve devices. Background Technology

[0002] Mitral valve disease is a common type of heart valve disease. Cardiovascular disease has long been the leading cause of death worldwide. Cardiovascular diseases include arteriosclerosis, myocardial infarction, stroke, arrhythmia, and valvular diseases. Valvular diseases, including aortic, pulmonary, mitral, and tricuspid valve diseases, are a major cause of heart failure, stroke, and other heart attacks. Mitral valve disease is the most common type of valvular disease.

[0003] Mitral valve diseases mainly include mitral regurgitation (MR) and mitral stenosis (MS). Mitral regurgitation refers to the inability of the mitral valve orifice to close completely due to abnormalities in any structure or function of the valve leaflets, annulus, chordae tendineae, papillary muscles, or left ventricle, allowing blood to flow back into the left atrium. Regurgitation leads to increased blood flow to the left atrium, elevated blood pressure, and increased pulmonary venous pressure. Severe cases can cause pulmonary edema, myocardial damage, heart failure, and even death. Mitral stenosis refers to the narrowing of the mitral valve orifice, preventing blood from flowing from the left atrium to the left ventricle. Insufficient oxygenated blood supply leads to fatigue and shortness of breath. Increased blood stagnation in the left atrium causes increased left atrial pressure and left atrial enlargement, which can also lead to pulmonary edema.

[0004] An aging society will bring about a huge number of patients, and the incidence of various valvular diseases increases with age. Among them, the incidence of mitral regurgitation is much higher than that of aortic stenosis, aortic regurgitation, and mitral stenosis. Considering that up to half of the patients do not undergo surgery due to factors such as poor cardiac function, multiple comorbidities, and advanced age, which make the surgery too risky, a large number of treatment needs are far from being met, such as the risk of outflow tract obstruction. Summary of the Invention

[0005] Therefore, it is necessary to provide a valve frame and an artificial valve device to address the aforementioned technical problems.

[0006] This application provides a valve frame, the valve frame comprising:

[0007] The main frame section has an internal space, a distal opening at the distal end, and a proximal opening at the proximal end.

[0008] The upper crown frame section is connected to the far end of the main frame section. The upper crown frame section is a ring-shaped frame and has an internal space. The internal space of the crown frame is connected to the internal space of the main frame through the far end opening.

[0009] An anchoring frame section, which is connected to the near end of the main frame section, wherein the axial length of the anchoring frame section is greater than the axial length of the main frame section.

[0010] In one embodiment, the valve frame includes:

[0011] The rear release frame section is connected to the proximal end of the main frame section.

[0012] In one embodiment, the rear release frame section includes a plurality of rear release support rods, the distal ends of which are respectively connected to different positions on the proximal end of the main frame section; and / or,

[0013] The anchoring frame section has an internal anchoring space, which is connected to the main frame internal space through the proximal opening. The rear release frame section is located in the internal anchoring space of the anchoring frame section.

[0014] In one embodiment, the radial dimension of the rear-release support rod gradually increases and then gradually decreases in the direction from the distal end to the proximal end.

[0015] In one embodiment, the rear release support rod includes a first rod segment and a second rod segment connected together. The distal end of the first rod segment is connected to the proximal end of the main frame segment, and the proximal end of the first rod segment and the distal end of the second rod segment are connected. In the direction from the distal end to the proximal end of the rear release support rod, the radial dimension of the first rod segment gradually increases, and the radial dimension of the second rod segment gradually increases.

[0016] In one embodiment, the ratio of the axial length of the main frame segment to the axial length of the petal frame is less than one-third; and / or,

[0017] The sum of the axial lengths of the main frame section and the upper crown frame section is less than the axial length of the anchoring frame section; and / or,

[0018] The radial dimension of the main frame section is smaller than the radial dimension of the upper crown frame section; and / or,

[0019] The upper crown section is provided with a plurality of spikes; and / or,

[0020] In the direction from the proximal end to the distal end of the upper crown frame segment, the radial dimension of the upper crown frame segment gradually increases; and / or,

[0021] The anchoring frame section is provided with barbs, the proximal end of which is connected to the anchoring frame section, and the distal end of which is a pointed structure; and / or,

[0022] The anchoring frame section includes several anchoring support rods, the distal ends of which are connected to different positions of the proximal end of the main frame section, and the space between the several anchoring support rods is the anchoring inner space inside the anchoring frame section.

[0023] In one embodiment, the main frame section is a cylindrical frame, and the upper crown frame section is an annular frame; wherein:

[0024] The diameter of the upper crown frame segment is greater than the diameter of the main frame segment; and / or, the diameter of the upper crown frame segment gradually increases in the direction from the proximal end to the distal end.

[0025] This application provides an artificial valve device, the artificial valve device comprising:

[0026] The valve frame;

[0027] Leaflets, the leaflets being disposed inside the petiole frame;

[0028] A membrane body, which is disposed outside the valve frame.

[0029] In one embodiment, the membrane comprises:

[0030] A first membrane segment covers the exterior of the upper crown segment and the main frame segment of the valve frame;

[0031] The second membrane segment is connected to the first membrane segment, and the second membrane segment is movable at least relative to the main frame segment.

[0032] In one embodiment, the weight per unit area of ​​the second membrane segment is less than the weight per unit area of ​​the first membrane segment; and / or,

[0033] The thickness of the second membrane segment is less than the thickness of the first membrane segment.

[0034] In the aforementioned valve frame and artificial valve device, the anchoring frame segment has an axially elongated structure within the overall valve frame structure. Compared to the anchoring frame segment, the main frame segment has a shorter axial length. This allows the main frame segment to be positioned relatively high, close to the upper side of the original valve annulus, after the valve frame is implanted into the left atrium and left ventricle. Furthermore, the hollow structure design on the main frame segment aligns its position with the sutured bovine pericardium, effectively preventing the risk of obstruction of the outflow tract of the left ventricle. Attached Figure Description

[0035] Figure 1 This is a diagram illustrating the usage state of an artificial valve device provided in one embodiment of this application.

[0036] Figure 2 A front view of a petal frame provided in one embodiment of this application.

[0037] Figure 3 This is a perspective view of a petiole frame provided in one embodiment of this application.

[0038] Figure 4 This is a diagram showing the fit between the valve frame and the leaflet according to one embodiment of this application.

[0039] Figure 5 This is a front view of an artificial valve device provided in one embodiment of this application.

[0040] Figure 6 This is a front view of a membrane provided in one embodiment of this application.

[0041] Figure 7 This is a top view of an artificial valve device provided in one embodiment of this application.

[0042] Icon labels:

[0043] 100. Left atrium; 200. Left ventricle; 300. Outflow tract;

[0044] 1000, Valve frame; 2000, Valve leaflets; 3000, Valve membrane;

[0045] 1100. Main frame section; 1200. Upper crown frame section; 1300. Anchoring frame section; 1400. Rear release frame section;

[0046] 1201, Spikes;

[0047] 1310. Anchoring support rod; 1301. Barbed part;

[0048] 1410. Release the support pole later; 1411. First pole segment; 1412. Second pole segment;

[0049] 3100, first membrane segment; 3200, second membrane segment. Detailed Implementation

[0050] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.

[0051] In the description of this application, it should be understood that if terms such as "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" appear, these terms indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0052] Furthermore, where the terms "first" and "second" appear, these terms are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, where the term "multiple" appears, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0053] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0054] In this application, unless otherwise expressly specified and limited, the use of descriptions such as "above" or "below" the second feature indicates that the first and second features are in direct contact or indirect contact via an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. Similarly, "below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0055] It should be noted that if an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. If an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. If so, the terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used in this application are for illustrative purposes only and do not represent the only possible implementation.

[0056] See Figures 1 to 3 As shown, this application provides a valve frame 1000, which includes a main frame segment 1100, a superior coronary frame segment 1200, and an anchoring frame segment 1300. The valve frame 1000 can be manufactured from medical nickel-titanium tubing through precision laser cutting, heat setting, electrochemical polishing, and other processes, resulting in a robust and reliable structural connection and low processing cost. The valve frame 1000 possesses deformation capability, exhibiting both contractile and expanded states, and can switch between these states under stress. This deformation capability manifests as excellent shape memory recovery in the valve frame 1000, allowing it to contract to a suitable, narrow-diameter delivery sheath before implantation, and to self-expand to the required size within the heart after release to replace the native mitral valve.

[0057] The term "distal" here refers to the end furthest from the operator during the surgical procedure, and "proximal" refers to the end closest to the operator during the surgical procedure. The "axial" direction of the valve frame 1000 can be defined as the direction from the distal to the proximal end (or from the proximal to the distal end), and the "radial" direction of the valve frame 1000 can be defined as the direction perpendicular to the axial direction of the valve frame 1000.

[0058] Unless otherwise defined, all technical and scientific terms used in this application have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in this application's specification is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

[0059] See Figure 2 and Figure 3As shown, the main frame section 1100 can be roughly shaped as a cylindrical frame. This cylindrical frame shape allows the main frame section 1100 to have an internal space, which is the internal space of the cylindrical frame. This internal space adapts to the degree of deformation of the main frame section 1100. The cylindrical frame can be various regular or irregular shapes such as cylindrical, elliptical, or square, and those skilled in the art can choose according to their needs; no limitation is made here. Furthermore, the main frame section 1100 has a distal opening at its distal end and a proximal opening at its proximal end, with the distal and proximal openings respectively communicating with the internal space of the main frame at the distal and proximal ends of the main frame section 1100.

[0060] Continue reading Figure 2 and Figure 3 As shown, the upper crown frame segment 1200 is connected to the distal end of the main frame segment 1100. The upper crown frame segment 1200 is a ring-shaped frame, which can be in various regular or irregular shapes such as circular rings, elliptical rings, and square rings, to adapt to the main frame segment 1100; no limitation is made here. The upper crown frame segment 1200 also has an internal space, which communicates with the internal space of the main frame through a distal opening. The anchoring frame segment 1300 is connected to the proximal end of the main frame segment 1100.

[0061] In the aforementioned petal frame 1000, the main frame section 1100, the upper crown frame section 1200, and the anchoring frame section 1300, the main frame section 1100 is located between the upper crown frame section 1200 and the anchoring frame section 1300. Furthermore, the dimensional relationship between the main frame section 1100 and the anchoring frame section 1300 is designed such that the axial length of the anchoring frame section 1300 is greater than the axial length of the main frame section 1100.

[0062] Therefore, the anchoring segment 1300 presents an axially elongated structural form within the overall structure of the valve frame 1000. In contrast, the main frame segment 1100 has a shorter axial length, allowing it to be positioned relatively higher after the valve frame 1000 is implanted into the left atrium 100 and left ventricle 200 (see reference). Figure 1 The main frame segment 1100 is positioned in an upper position, close to the upper side of the original valve annulus. At the same time, by utilizing the hollow structure design on the main frame segment 1100, the position of the hollow structure on the main frame segment 1100 corresponds to the orientation of the sutured bovine pericardium, which can effectively prevent the risk of obstruction of the outflow tract 300 of the left ventricle 200.

[0063] In one embodiment, not only is the axial length of the anchoring frame segment 1300 limited to be greater than the axial length of the main frame segment 1100, but also, in terms of the overall size design proportion of the petiole frame 1000, the ratio of the axial length of the main frame segment 1100 to the axial length of the petiole frame 1000 is limited to less than one-third. Furthermore, the ratio of the sum of the axial lengths of the main frame segment 1100 and the upper crown segment 1200 to the axial length of the petiole frame 1000 is limited to less than one-half (which is also equivalent to the sum of the axial lengths of the main frame segment 1100 and the upper crown segment 1200 being less than the axial length of the anchoring frame segment 1300). In one embodiment, the following ratio can be defined:

[0064] Upper frame section 1200: Main frame section 1100: Anchoring frame section 1300 = 2:2:5; or,

[0065] Upper crown frame section 1200: main frame section 1100: anchoring frame section 1300 = 2:3:6.

[0066] Those skilled in the art can set the above ratios based on the above technical concept, and no limitation is made here. This results in the main frame section 1100 being relatively higher (see reference). Figure 1 (The upper part of the main frame section 1100), and with the help of the hollow structure design on the main frame section 1100, the risk of obstruction of the outflow tract 300 of the left ventricle 200 can be effectively prevented.

[0067] In one embodiment, the radial dimension of the main frame segment 1100 may also be designed to be smaller than the radial dimension of the upper crown frame segment 1200, which makes the upper crown frame segment 1200 appear as follows: Figure 2 and Figure 3 The large-size form shown can be similar to, for example... Figure 2 and Figure 3 The lotus-shaped structure is shown. Due to the large size of the superior coronary artery segment 1200, it can be larger than the original valve annulus. Based on its large size and shape, it can effectively fit onto the original valve annulus, ensuring that the entire superior coronary artery segment 1200 is located within the left atrium 100. At this point, the superior coronary artery segment 1200 can closely adhere to the upper side of the original valve annulus, resulting in a better seal and effectively reducing the risk of paravalvular leakage.

[0068] Meanwhile, the upper coronary artery segment 1200 is provided with a plurality of spikes 1201, which are evenly distributed around the circumference of the annular frame of the upper coronary artery segment 1200. The spikes 1201 can anchor to a certain extent with the tissue of the left atrium 100, improving the stability of the upper coronary artery segment 1200 within the left atrium 100. The radial dimension of the upper coronary artery segment 1200 can gradually increase from the proximal to the distal end. For example, in one embodiment, when the main frame segment 1100 is a cylindrical frame and the upper coronary artery segment 1200 is an annular frame, the gradual increase in the radial dimension of the upper coronary artery segment 1200 can be manifested as a gradual increase in the diameter of the upper coronary artery segment 1200 from the proximal to the distal end. In this case, the diameter of the upper coronary artery segment 1200 can also be limited to be larger than the diameter of the main frame segment 1100.

[0069] In one embodiment, the anchoring frame section 1300 is provided with a barb portion 1301, the proximal end of which is connected to the anchoring frame section 1300, and the distal end of which is a pointed structure. The anchoring frame section 1300 includes a plurality of anchoring support rods 1310, the distal ends of which are respectively connected to different positions on the proximal end of the main frame section 1100. For example, the plurality of anchoring support rods 1310 are arranged circumferentially on the proximal end of the main frame section 1100. Figure 2 and Figure 3 As shown, the space between the anchoring support rods 1310 is the anchoring inner space inside the anchoring frame section 1300. In one embodiment, the number of anchoring support rods 1310 is set to three, and the three anchoring support rods 1310 are evenly distributed in a triangular pattern along the circumferential direction at the proximal end of the main frame section 1100, so as to minimize the stimulation of the ventricular wall and not affect the contraction or expansion of the ventricular cavity.

[0070] As can be seen from the above, the anchoring segment 1300 is longer in the axial direction of the valve frame 1000 than the upper coronary segment 1200 and the main frame segment 1100, making the anchoring segment 1300 appear slender and flexible. At the same time, the anchoring segment 1300 is equipped with barbs 1301. Therefore, the anchoring segment 1300 can be designed based on its high elasticity and outward expansion structure, which is conducive to fixing the proximal end of the valve frame 1000 to the ventricular wall and forming a traction trend with the upper coronary segment 1200, effectively fixing the artificial mitral valve at the target lesion site and reducing the displacement of the valve frame 1000 towards the atrium.

[0071] In one embodiment, the valve frame 1000 may further include a posterior release frame segment 1400, which is connected to the proximal end of the main frame segment 1100. The posterior release frame segment 1400 maintains the positional stability of the artificial valve device during implantation. After the superior coronal frame segment 1200 and the anchoring frame segment 1300 are released, the posterior release frame segment 1400 is released, thereby completing the implantation of the artificial valve device. This not only regulates the release of the artificial valve device but also reduces the risk of misoperation, effectively improving the success rate of the surgery. The posterior release frame segment 1400 can take various forms. For example, the posterior release frame segment 1400 includes several posterior release support rods 1410, the distal ends of which are connected to different positions on the proximal end of the main frame segment 1100, such that the several posterior release support rods 1410 can be arranged as follows: Figure 2 and Figure 3 The distribution shown is uniformly distributed along the circumference of the main frame section 1100.

[0072] In the relative positional relationship between the anchoring frame section 1300 and the rear release frame section 1400, the interior of the anchoring frame section 1300 can be defined as having an anchoring inner space. For example, the space between several anchoring support rods 1310 is the anchoring inner space inside the anchoring frame section 1300. The anchoring inner space is connected to the main frame inner space through a proximal opening. The rear release frame section 1400 is located in the anchoring inner space of the anchoring frame section 1300.

[0073] In one embodiment, the radial dimension of the rear release support rod 1410 gradually increases and then gradually decreases in the direction from the distal end to the proximal end. For example, in one embodiment, the rear release support rod 1410 includes a first rod segment 1411 and a second rod segment 1412 connected together. The distal end of the first rod segment 1411 is connected to the proximal end of the main frame segment 1100, and the proximal end of the first rod segment 1411 is connected to the distal end of the second rod segment 1412. In the direction from the distal end to the proximal end of the rear release support rod 1410, the radial dimension of the first rod segment 1411 gradually increases, and the radial dimension of the second rod segment 1412 gradually increases.

[0074] The first frame segment 1411 and the second frame segment 1412 can be designed as straight rods, curved rods, single-rod structures, or multi-rod structures. For example, in one embodiment, the first frame segment 1411 can be composed of two rods, the distal ends of which are connected to the proximal ends of the main frame segment 1100, and the proximal ends of the two rods are connected, making the first frame segment 1411 triangular in shape. Meanwhile, the second frame segment 1412 can be composed of one rod, the distal end of which is connected to the proximal ends of the two rods in the first frame segment 1411. In addition, those skilled in the art can design the structure, dimensions, etc., of the release support rod 1410 according to actual needs, which are not limited here.

[0075] See Figures 4 to 7 As shown, this application provides an artificial valve device, which includes the aforementioned valve frame 1000 and leaflets 2000 and a membrane 3000 disposed on the valve frame 1000. The leaflets 2000 are located inside the valve frame 1000 to mimic the function of the native leaflets, while the membrane 3000 is located outside the valve frame 1000. The leaflets 2000 can be made from two or three pieces of bovine pericardial tissue of uniform size and thickness, processed through a series of cutting and tissue curing processes, and then tightly sutured to the inner side of the valve frame 1000 using medical polymer sutures. Specifically, they can be located inside the main frame segment 1100 of the valve frame 1000. The two or three leaflets 2000 are evenly distributed and can only open towards the ventricular cavity, closing towards the atrium, effectively mimicking the opening and closing action of the native mitral valve leaflets.

[0076] In one embodiment, the membrane body 3000 includes a first membrane segment 3100 and a second membrane segment 3200, which have different shapes, positions, and materials. For example, the first membrane segment 3100 covers the exterior of the upper crown segment 1200 and the main frame segment 1100 of the valve frame 1000, the second membrane segment 3200 is connected to the first membrane segment 3100, and the second membrane segment 3200 is movable at least relative to the main frame segment 1100.

[0077] In one embodiment, the weight per unit area of ​​the second membrane segment 3200 is less than that of the first membrane segment 3100, and the membrane thickness of the second membrane segment 3200 is less than that of the first membrane segment 3100. Here, the weight per unit area refers to the fact that the second membrane segment 3200 is lighter and thinner when the areas of the two are the same. The second membrane segment 3200 is thinner and lighter than the first membrane segment 3100. The thinner second membrane segment 3200 can be flipped upward by the backflow of blood, that is, the distal end of the second membrane segment 3200 is tightly connected to the valve frame 1000. The proximal end of the second membrane segment 3200 is designed to be movable relative to the main frame segment 1100, so that the proximal opening of the second membrane segment 3200 can be flipped back to the underside of the original valve annulus when the heart contracts, which can further prevent the risk of paravalvular leakage and reduce the risk of postoperative complications.

[0078] For example, the first membrane segment 3100 is made of a PET film with a fluffy surface, which greatly increases the sealing performance of the artificial mitral valve. The second membrane segment 3200 is made of thin ePTFE (expanded PTFE). The fluffy PET film can be woven from medical-grade PET filaments, making it dense and thin, effectively preventing blood leakage while facilitating endothelial cell adhesion. The thin ePTFE can be flushed upwards by blood flow, further preventing the risk of paravalvular leakage and reducing the risk of postoperative complications.

[0079] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0080] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. A valve frame for the mitral valve, characterized in that, The valve frame includes: The main frame section has an internal space, a distal opening at the distal end, and a proximal opening at the proximal end. The upper crown frame section is connected to the far end of the main frame section. The upper crown frame section is a ring-shaped frame with an internal crown frame space. The internal crown frame space communicates with the internal space of the main frame through the far end opening. The radial dimension of the main frame section is smaller than the radial dimension of the upper crown frame section. An anchoring frame section, which is connected to the proximal end of the main frame section, and the axial length of the anchoring frame section is greater than the axial length of the main frame section; the anchoring frame section has an internal anchoring space, which communicates with the internal space of the main frame through the proximal end opening; The rear release frame section is connected to the proximal end of the main frame section and is located in the anchoring inner space of the anchoring frame section.

2. The petiole frame according to claim 1, characterized in that, The rear release frame section includes a plurality of rear release support rods, the distal ends of which are respectively connected to different positions of the proximal end of the main frame section.

3. The petiole frame according to claim 2, characterized in that, In the direction from the distal end to the proximal end of the rear release support rod, the radial dimension of the rear release support rod first gradually increases and then gradually decreases.

4. The petiole frame according to claim 2, characterized in that, The rear release support rod includes a first rod segment and a second rod segment connected together. The distal end of the first rod segment is connected to the proximal end of the main frame segment, and the proximal end of the first rod segment and the distal end of the second rod segment are connected. In the direction from the distal end to the proximal end of the rear release support rod, the radial dimension of the first rod segment gradually increases, and the radial dimension of the second rod segment gradually increases.

5. The petiole frame according to claim 1, characterized in that, The ratio of the axial length of the main frame segment to the axial length of the petal frame is less than one-third; and / or, The sum of the axial lengths of the main frame section and the upper crown frame section is less than the axial length of the anchoring frame section; and / or, The upper crown section is provided with a plurality of spikes; and / or, In the direction from the proximal end to the distal end of the upper crown frame segment, the radial dimension of the upper crown frame segment gradually increases; and / or, The anchoring frame section is provided with barbs, the proximal end of which is connected to the anchoring frame section, and the distal end of which is a pointed structure; and / or, The anchoring frame section includes several anchoring support rods, the distal ends of which are connected to different positions of the proximal end of the main frame section, and the space between the several anchoring support rods is the anchoring inner space inside the anchoring frame section.

6. The petiole frame according to claim 5, characterized in that, The main frame section is a cylindrical frame, and the upper crown frame section is a circular frame; wherein: The diameter of the upper crown frame segment is greater than the diameter of the main frame segment; and / or, the diameter of the upper crown frame segment gradually increases in the direction from the proximal end to the distal end.

7. An artificial valve device, characterized in that, The artificial valve device includes: Valve frame as described in any one of claims 1-6; Leaflets, the leaflets being disposed inside the petiole frame; A membrane body, which is disposed outside the valve frame.

8. The artificial valve device according to claim 7, characterized in that, The membrane comprises: A first membrane segment covers the exterior of the upper crown segment and the main frame segment of the valve frame; The second membrane segment is connected to the first membrane segment, and the second membrane segment is movable at least relative to the main frame segment.

9. The artificial valve device according to claim 8, characterized in that, The weight per unit area of ​​the second membrane segment is less than that of the first membrane segment.

10. The artificial valve device according to claim 8, characterized in that, The thickness of the second membrane segment is less than the thickness of the first membrane segment.

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