Lymphatic drainage device

Abstract

The present invention relates to a lymphatic drainage device. The lymphatic drainage device comprises: an anti-clogging support, a collecting cavity is formed inside the anti-clogging support, the anti-clogging support is used to support the biological tissue around the position to be drained to maintain the shape of the collecting cavity, and the collecting cavity is used to collect the lymph produced by the lymphatic tissue around the position to be drained; a drainage tube, the two ends of the drainage tube are an inlet end and an outlet end, the inlet end is used to introduce the lymph into the drainage tube, and the outlet end is used to guide the lymph out of the drainage tube, and the inlet end extends into the collecting cavity; and an implantable pump, the implantable pump is connected to the drainage tube, and is used to pump the lymph in the collecting cavity from the inlet end of the drainage tube and pump it out from the outlet end. The present invention realizes continuous drainage of cervical lymph by designing a lymphatic drainage device with an automatic adjustment of negative pressure suction function.

Description

Technical Field

[0001] The present invention relates to the technical field of lymphatic drainage, and in particular to a lymphatic drainage device. Background Art

[0002] Alzheimer's disease is one of the most common neurodegenerative diseases and the leading cause of dementia in the elderly. Studies have shown that blockage of the lymphatic system in the brain can cause the accumulation of substances such as beta-amyloid protein (Aβ) and tau protein associated with Alzheimer's disease, which in turn aggravates the patient's symptoms. Draining lymph fluid in the neck can drain Aβ and tau substances and may help slow or stop the progression of Alzheimer's disease. However, most of the currently designed lymphatic drainage devices use needle puncture of lymphatic vessels for drainage, which is not suitable for the small lymphatic vessels in the neck. Summary of the invention

[0003] In view of this, the present invention provides a lymphatic drainage device to solve or alleviate one or more of the above problems and other problems existing in the prior art.

[0004] In order to achieve the above-mentioned object, the present invention provides a lymphatic drainage device, wherein the lymphatic drainage device comprises:

[0005] An anti-clogging stent, wherein a collecting cavity is formed inside the anti-clogging stent, and the anti-clogging stent is used to support biological tissues around the position to be drained to maintain the shape of the collecting cavity, and the collecting cavity is used to collect lymph produced by the lymphatic tissues around the position to be drained;

[0006] a drainage tube, wherein both ends of the drainage tube are an inlet end and an outlet end, the inlet end is used to introduce lymph fluid into the drainage tube, the outlet end is used to guide lymph fluid out of the drainage tube, and the inlet end extends into the collection cavity; and

[0007] An implantable pump is connected to the drainage tube and is used to pump lymph fluid in the collection chamber into the inlet end of the drainage tube and pump it out from the outlet end.

[0008] In the lymphatic drainage device as described above, optionally, the drainage tube includes an inner groove section starting from the inlet end, the inner groove section includes an inner groove section outer wall and a partition connected to the inner side of the inner groove section outer wall, the partition is used to divide the interior of the inner groove section into multiple channels, the length of the inner groove section is 2.5 cm to 3.5 cm, and the inlet end of the drainage tube extends into the anti-clogging bracket by 0.8 cm to 1.2 cm.

[0009] In the lymphatic drainage device as described above, optionally, the partition extends along the axial direction of the inner groove segment so that the axes of the multiple channels are parallel to each other.

[0010] In the lymphatic drainage device as described above, optionally, the cross-sectional shape of the partition is an I-shape, a square, a triangle, a well-shape or an arc triangle, which divides the interior of the inner groove segment into 5, 5, 4, 9 and 4 channels respectively.

[0011] In the lymphatic drainage device as described above, optionally, a perforated area starting from the inlet end is provided on the outer wall of the inner groove segment, and the perforated area includes a plurality of three-dimensional drainage holes connecting the channel and the collecting chamber, and the length of the perforated area is 1.2 cm to 1.8 cm.

[0012] In the lymphatic drainage device as described above, optionally, a plurality of communication holes are provided on the partition, and the communication holes are used to connect the plurality of channels to each other.

[0013] In the lymphatic drainage device as described above, optionally, the length of the drainage tube is greater than 50 cm and less than 100 cm.

[0014] In the lymphatic drainage device as described above, optionally, the anti-clogging bracket includes a frame unit and a connecting seat, one end of the frame unit is connected to the connecting seat, the frame unit extends in a curved manner along the axial direction of the connecting seat, a plurality of the frame units are arranged and distributed along the circumferential direction of the connecting seat, the frame units surround and form the collecting cavity, the connecting seat is fixedly connected to the drainage tube, and the anti-clogging bracket is in the shape of an umbrella, a polyhedron, a sphere or an ellipsoid.

[0015] In the lymphatic drainage device as described above, optionally, the anti-blockage stent is made of shape memory alloy, and has a folded state and a restored state. In the folded state, the anti-blockage stent can reduce its size by folding, and in the restored state, the anti-blockage stent can automatically restore its stretched shape.

[0016] In the lymphatic drainage device as described above, optionally, the implantable pump is a unidirectional peristaltic pump, which continuously pumps the liquid in the drainage tube from the inlet end to the outlet end in a unidirectional manner.

[0017] In the lymphatic drainage device as described above, optionally, the implantable pump comprises:

[0018] an implantable power supply device, the power supply device being electrically connected to the implantable pump to continuously supply power to the implantable pump; and

[0019] A pressure sensor is used to measure the pressure in the drainage tube, the power supply device adjusts the negative pressure of the implantable pump according to the measurement signal of the pressure sensor, the pressure sensor is fixed on the drainage tube, and the wall of the drainage tube at the fixed position of the pressure sensor is thinner than the wall of the drainage tube at other positions.

[0020] The present invention realizes continuous drainage of cervical lymph fluid by designing a lymphatic drainage device with an automatic adjustment negative pressure suction function. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] The disclosure of the present invention will become more apparent with reference to the accompanying drawings. It should be understood that these drawings are only for illustrative purposes and are not intended to limit the scope of protection of the present invention. In the drawings:

[0022] Figure 1 is a stereoscopic diagram of an embodiment of a lymphatic drainage device of the present invention;

[0023] Figure 2 for Figure 1 A partial enlarged view of the inlet end of the drainage tube of the embodiment;

[0024] Figure 3 is a schematic diagram of the AA cross section of the inlet end of the drainage tube;

[0025] Figure 4 It is a three-dimensional diagram of an inner tank section having three-dimensional drainage holes;

[0026] Figure 5 It is a three-dimensional diagram of the inner groove section extending into the anti-blocking bracket;

[0027] Figure 6 A front view of the anti-blocking bracket.

[0028] Figure markings: 1-drainage tube; 2-implantable pump; 3-power supply device; 4-pressure sensor; 5-anti-clogging bracket; 6-three-dimensional drainage hole; 7-inlet end; 8-outlet end; 9-deep cervical lymphatic vessel; 10-open end of lymphatic vessel; 11-front section of drainage tube; 12-back section of drainage tube; 13-one-way valve; 14-outer wall of inner groove section; 15-partition; 16-channel; 17-inner groove section; 18-punching area; 19-frame unit; 20-lymph node; 21-connecting seat; 22-collecting chamber; 23-folded state; 24-restored state; 26-connecting hole. DETAILED DESCRIPTION

[0029] With reference to the accompanying drawings and specific embodiments, the structure, composition, characteristics and advantages of a lymphatic drainage device of the present invention will be described below in an exemplary manner. However, all descriptions should not be used to form any limitation on the present invention.

[0030] For any single technical feature described or implied in the embodiments mentioned in this document, or any single technical feature displayed or implied in the accompanying drawings, the present invention still allows any combination or deletion between these technical features (or their equivalents) without any technical obstacles, and thus it should be considered that these more embodiments according to the present invention are also within the scope of the description of this document.

[0031] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features.

[0032] The terms "front" and "rear" are used in this application document to describe the relative positions and directions of the components of the lymphatic drainage device of the present invention in the extension direction of the drainage tube, with the direction close to the inlet end of the drainage tube being "front" and the direction close to the outlet end of the drainage tube being "rear". The front section of the drainage tube is closer to the inlet end of the drainage tube than the rear section of the drainage tube.

[0033] Figure 1 It is a stereoscopic diagram of an embodiment of a lymphatic drainage device of the present invention.

[0034] The lymphatic drainage device of the present invention comprises an anti-blocking bracket 5, a drainage tube 1 and an implantable pump 2. The anti-blocking bracket 5 can be placed on the neck of a human body, and a collecting cavity 22 is formed inside the anti-blocking bracket. The anti-blocking bracket is used to support biological tissues around the position to be drained, such as fat and muscle, to maintain the shape of the collecting cavity, and the collecting cavity is used to collect lymph produced by the lymphatic tissue around the position to be drained. The anti-blocking bracket 5 can be an umbrella-shaped, polyhedral, spherical or ellipsoidal shape, or a mesh or sheet support structure, or an arrangement and combination of the above shapes and support structures, including but not limited to spherical mesh, spherical sheet and other structures. The anti-blocking bracket 5 is used to place the open end 10 of the deep neck lymphatic vessel, and the open end 10 of the deep neck lymphatic vessel is processed by surgical operation on the deep neck lymphatic vessel 9 of the neck. The processing method can be transverse cutting or longitudinal cutting of the side wall to form the open end 10 of the deep neck lymphatic vessel, and the lymph node 20 is connected to the end of the lymphatic vessel and can also secrete lymph. After the surgical treatment is completed, the deep cervical lymphatic vessel 9 and the lymph nodes 20 can be extended into the anti-blockage stent 5, and the open end 10 of the deep cervical lymphatic vessel is then located in the anti-blockage stent 5. The inlet end 7 of the drainage tube is extended into the anti-blockage stent 5 and is firmly connected. The inlet end 7 is adjacent to the open end 10 of the deep cervical lymphatic vessel and is used to suck the lymph fluid flowing out of the open end 10 of the lymphatic vessel or the lymph nodes 20.

[0035] The two ends of the drainage tube 1 are an inlet end 7 and an outlet end 8, and the inlet end extends into the collection cavity. The drainage tube 1 can be configured to guide the lymph fluid to flow unidirectionally from the inlet end 7 to the outlet end 8 in the drainage tube 1. In order to achieve this unidirectional flow, the lymphatic drainage device of the present invention may include an implantable pump 2, which divides the drainage tube 1 into a front section 11 of the drainage tube and a rear section 12 of the drainage tube. The implantable pump 2 can generate negative pressure at the inlet end of the drainage tube through unidirectional rotation, continuously inhale liquid, and continuously transport the lymph fluid in the drainage tube 1 from the front section 11 of the drainage tube to the rear section 12 of the drainage tube, and pump it out from the outlet end.

[0036] As an optional embodiment, the implantable pump 2 can be a unidirectional peristaltic pump, which can be fixedly connected to the drainage tube 1 and has a rotating head for squeezing the drainage tube 1. The rotating head continuously squeezes the drainage tube 1 when rotating, so that the liquid in the tube continuously flows from the front section 11 of the drainage tube to the rear section 12 of the drainage tube. The implantable peristaltic pump can form a stable negative pressure at the inlet end 7 of the drainage tube 1 to provide power for pumping the liquid in the collection cavity 22. The implantable peristaltic pump has a large torque, low power consumption, stable operation, and high transmission accuracy, and can accurately adjust the suction speed of the lymph fluid. The rotating head can maintain unidirectional rotation, so that the liquid in the drainage tube is pumped unidirectionally from the inlet end to the outlet end, achieving a non-return effect, preventing the derived lymph fluid from flowing back and preventing external liquid from flowing back from the outlet end 8 of the drainage tube to the inlet end 7 and invading the collection cavity 22 and the open end 10 of the deep neck lymphatic vessel, avoiding possible infection problems.

[0037] Alternatively, if Figure 1 As shown in the partial enlarged view in FIG. 1 , a one-way valve 13 can be provided in the drainage tube 1. The one-way valve 13 can be provided behind the implantable pump 2 of the drainage tube 1. In other words, the one-way valve 13 is located on one side of the outlet end 8 of the implantable pump 2. At this time, the implantable pump 2 can adopt other types of liquid-driven pumps, and need not be limited to a one-way peristaltic pump. The one-way valve 13 can include an elastic membrane flap. When the implantable pump 2 pumps lymph from the front section 11 of the drainage tube to the rear section 12 of the drainage tube, the membrane flap is separated due to the pressure difference on both sides of the one-way valve 13, so that the one-way valve 13 is opened, providing a channel for transporting lymph. When the implantable pump 2 stops pumping lymph or rotates in the opposite direction, the pressure difference on both sides disappears or reverses, and the membrane flap automatically closes due to its own elasticity, so that the one-way valve 13 is closed, thereby realizing the function of the drainage tube 1 to transport lymph in one direction. In order for the one-way valve 13 to respond quickly to the action of the implantable pump 2, the one-way valve 13 can be set at a position close to the implantable pump 2.

[0038] As an optional embodiment, the lymphatic drainage device may also include an implantable power supply device 3, which is electrically connected to the implantable pump 2 to continuously supply power to the implantable pump 2. The power supply device 3 may adopt a magnetic induction charging design or use a long-lasting large-capacity battery to achieve sustainable and long-term power supply. A reliable power supply device may extend the service life of a single implantation of the drainage device and extend the time interval for patients to replace the power supply device. The power supply device 3 may be fixed to the outer wall of the drainage tube 1, the outer shell of the implantable pump 2, or sutured to human tissues such as the fascia near the implantable pump 2, so as to shorten the length of the power line and signal line between the implantable pump 2 and the power supply device 3 as much as possible, thereby improving the stability of the power supply function. The power supply device maintains outputting current to the implantable pump, so that the inlet end of the drainage tube 1 continuously draws lymph fluid and discharges it from the outlet end 8 into the abdominal cavity or bladder.

[0039] Optionally, the inlet end 7 of the drainage tube 1 can be placed near the zone II lymph nodes in the carotid triangle of the human body. Specifically, this position is an anatomical landmark with the accessory nerve at the outer edge, the internal jugular vein at the inner edge, and the cervical loop at the lower edge. Collecting lymph fluid from this position can effectively perform deep cervical lymphatic drainage for patients, timely discharge metabolites related to senile degenerative diseases such as Alzheimer's disease in the brain, and improve cognitive function of patients with senile dementia.

[0040] As an alternative embodiment, the implantable pump may also include a pressure sensor 4, which may be fixedly attached to the outer wall of the drainage tube 1. The pressure sensor may be electrically connected to a power supply device and transmit a pressure measurement signal thereto. The power supply device adjusts the output current to the implantable pump 2 according to the signal to adjust its power and flow, thereby controlling the negative pressure value in the drainage tube 1. The pressure sensor 4 may also transmit the measurement signal directly to the implantable pump 2, which adjusts the power and flow by itself. Since the accumulation rate of the lymph fluid in the collection chamber 22 changes with the state of the human body, the implantable pump 2 with the function of automatically adjusting the negative pressure can avoid excessive suction of lymph fluid or tissue fluid, so that a large negative pressure will not be formed in the collection chamber, causing blockage in the collection chamber, and can also avoid the problem of untimely drainage. In an alternative embodiment, the pressure sensor 4 can be fixed to a weaker part of the wall of the drainage tube 1, which is conducive to more accurate measurement of the pressure changes in the drainage tube. Specifically, the wall of the drainage tube at the fixed position of the pressure receptor is thinner than the wall of other parts of the drainage tube. The pressure feedback there is more sensitive, which can transmit the pressure in the drainage tube more accurately and quickly, thereby improving the accuracy and timeliness of the negative pressure regulation of the implantable pump.

[0041] Optionally, the housings of the implantable pump 2, power supply device 3 and pressure sensor 4 can all be made of biocompatible materials, and these structures can be used as implantable devices that can be fixedly connected to the subcutaneous part of the chest wall or other firmly fixed positions to improve the position stability of the lymphatic drainage device.

[0042] As an alternative embodiment, the anti-blockage stent 5 can be an open mesh stent structure or a structure with an open top and a closed perimeter. The anti-blockage stent with a mesh stent structure can better conform to the surrounding human tissues and disperse the pressure exerted by the human tissues on the anti-blockage stent due to negative pressure suction. The anti-blockage stent with an open top and a closed perimeter has higher support strength and is suitable for higher-flow negative pressure aspiration.

[0043] Figure 2 is Figure 1 a partial enlarged view of the inlet end of the drainage tube in the middle embodiment, Figure 3 is a schematic cross-sectional view of the A-A cross-section of the inlet end of the drainage tube. The following will describe the implementation manner of the inlet end 7 of the drainage tube 1 in conjunction with Figure 2 and Figure 3 illustrate the implementation manner of the inlet end 7 of the drainage tube 1.

[0044] As an alternative embodiment, the drainage tube 1 may include an inner groove section 17 starting from its inlet end 7. The inner groove section 17 is shown by the hatched area in Figure 2 and the internal structure of the inner groove section 17 can be designed as a multi-groove structure. The inner groove section may include an outer wall 14 of the inner groove section and a partition 15 connected to the inner side of the outer wall 14 of the inner groove section. The partition divides the interior of the inner groove section into multiple channels. The partition 15 forms a multi-groove structure, and different structures of the partition 15 form different cross-sectional shapes. Figure 3 shows 5 different cross-sectional shapes. Moreover, the partition 15 can be designed to be parallel to the axis direction of the inner groove section, so that the cross-sectional shape of the partition 15 is the same at different lengths of the inner groove section. The stable cross-sectional shape can make the flow velocity and direction of lymph fluid in the drainage tube 1 more stable. The inner groove section 17 is located on the drainage tube 1 and extends axially, and its length can be 2.5 cm to 3.5 cm, preferably 3 cm. A part of the inner groove section 17 can extend into the anti-blockage stent 5 to suck lymph fluid, and the other part is fixed in the human tissue, so that the inner groove section 17 is fixed more firmly. The aforementioned human tissue is shown by the "X" shaped shadow in Figure 2 and tightly wraps around the outer sides of the inner groove section 17 and the drainage tube 1.

[0045] As an alternative embodiment, the partition 15 can have the following characteristics, that is, the partition extends along the axial direction of the inner groove section, so that the axes of multiple channels are parallel to each other. The cross-sectional shapes of the partition and the channels with this structural characteristic do not change due to the length position where they are located, thereby keeping the flow direction and flow velocity of the lymph fluid transported by the inner groove section 17 stable. Further, an alternative embodiment is proposed: the cross-sectional shape of the partition 15 can be in the shape of "I", square, triangle, "well" shape, and "arc triangle" as shown in Figure 3 (a) to (e). The cross-sectional shape of the partition 15 is not limited to these 5 types, and other symmetric and asymmetric shapes should also be within the protection scope of the present invention.

[0046] Different-shaped partitions 15 are provided in the inner groove section 17 of the drainage tube 1, and the different-shaped partitions 15 divide the interior of the inner groove section 17 into multiple channels 16. The above-mentioned partitions with different shapes from Figure 3 (a) to (e) divide the interior of the inner groove section into 5, 5, 4, 9, and 4 channels respectively. Specifically, Figure 3 the "I"-shaped one in (a) and Figure 3 the square-section partition in (b) divide the interior of the inner groove section 17 into 5 channels; Figure 3 the triangular one in (c) and Figure 3 the "arc triangle"-shaped section partition in (e) divide the interior of the inner groove section 17 into 4 channels; Figure 3 the "well"-shaped section partition in (d) divides the interior of the inner groove section 17 into 9 channels. A large number of channels is beneficial to preventing the blockage of the drainage tube.

[0047] The anti-blockage bracket 5 with a reticular support structure (see Figure 1 ) has relatively large gaps. The inlet end 7 of the drainage tube 1, the lymph node 20 (see Figure 1 ) and the open end 10 of the deep cervical lymphatic vessel (see Figure 1 ) extend into the anti-blockage bracket 5. Since the drainage tube 1 is implanted in the body, with the movement of the body or the growth of tissues, the above-mentioned lymph node 20 and the open end 10 of the lymphatic vessel may enter the inlet end 7 of the drainage tube 1. If the lymph node 20 or the open end 10 of the lymphatic vessel continues to grow after entering the inlet end 7 of the drainage tube 1 and the radial dimension increases, it is very likely to completely block the inlet end 7 of the drainage tube 1, resulting in the failure of this lymphatic drainage device. The inner groove section 17 at the inlet end 7 of the drainage tube 1 is divided into several channels 16 by the partition 15. The partition can separate the lymph nodes, lymphatic vessels or other biological tissues invading the inner groove section. Even if several channels 16 are blocked, the remaining channels 16 can still be used to transport lymph fluid. In contrast, the drainage tube 1 without the inner groove section 17 is more likely to be completely blocked, with low reliability, increasing the possibility that the patient needs to undergo surgery to dredge the drainage tube 1.

[0048] In addition, since the drainage tube 1 is implanted in the body and the inner groove section is close to the inlet end of the drainage tube, it may be subjected to a radially inward pressure from human tissues. The partition 15 can increase the radial stiffness of the inner groove section. The design of the partition makes the inner groove section conducive to avoiding being squeezed and narrowed, ensuring the efficiency of this lymphatic drainage device in sucking lymph fluid under negative pressure.

[0049] As an alternative embodiment, since the body sizes of people are different, the drainage tube 1 can be customized with different lengths to adapt to patients with different body lengths, making the drainage tube 1 long enough so that the outlet end 8 (see Figure 1) can be placed in the abdominal cavity or bladder of the human body. If the drainage tube is too long, it can also be trimmed to a suitable length. Specifically, since the length from the mandible to the lower abdomen of an average adult is less than 100 cm, the length of the drainage tube 1 of the lymphatic drainage device can be set to be greater than 50 cm and less than 100 cm. In addition, the outlet end 8 can be fixed to the posterior wall of the rectus abdominis or punctured and fixed and buried in the bladder, and the middle pipeline of the drainage tube 1 from the neck to the abdominal cavity or bladder can run in the subcutaneous fat layer. The material of the drainage tube 1 can be silicone or other flexible and biocompatible non-degradable materials. The inside of the lumen of the drainage tube 1 can be designed to have a uniform diameter, or the drainage tube can be designed to have a thicker inlet end 7 and a thinner outlet end 8, thereby further reducing the possibility of blockage of the inlet end 7 and making it easier for the outlet end 8 to penetrate the abdominal cavity or bladder.

[0050] Figure 4 It is a three-dimensional diagram of the inner groove section with three-dimensional drainage holes.

[0051] Optionally, a perforated area 18 starting from the inlet end 7 may be provided on the outer wall 14 of the inner groove section, and the perforated area 18 includes a plurality of three-dimensional drainage holes 6. The three-dimensional drainage holes 6 are used to connect the channel 16 and the collection chamber 22 (see Figure 1 ). The three-dimensional drainage holes are distributed along the axial direction of the inner groove section, and cooperate with the inlet end of the drainage tube to form a three-dimensional channel for introducing lymph into the drainage tube. The three-dimensional drainage holes 6 increase the number and area of ​​the channels that can be used to introduce lymph, improve the drainage efficiency, and reduce the possibility of blockage of the inlet end 7. As an optional embodiment, the partition 15 can be provided with the following Figure 4 As shown in the figure, different channels 16 are connected through the connecting holes 26 at different lengths from the inlet end 7. Therefore, even if some channels 16 near the inlet end are blocked, lymph fluid can still flow into each channel through the deeper connecting holes 26, so that the available cross-sectional area of ​​the inner groove section 17 will not be reduced, thereby ensuring that the flow conduction capacity of the inner groove section 17 is stable.

[0052] The perforated area extends along the axial direction of the drainage tube. The optional length of the perforated area is 1.2 cm to 1.8 cm, preferably 1.5 cm. The length of the perforated area should be smaller than the inner groove section 17. The three-dimensional drainage holes 6 can be evenly distributed in the perforated area 18, and the connecting holes 26 can be evenly distributed in the partition 15. The three-dimensional drainage holes 6 and the multi-groove-like structure formed by the partition 15 in the inner groove section 17 are connected to ensure that even if the inlet end 7 of the drainage tube is completely blocked, the drainage tube can still drain normally. The multi-groove-like structure formed by the partition 15 in the inner groove section 17 includes but is not limited to Figure 3 Any one of (a) to (e). The multi-groove structure formed by the partition 15 and the tube wall, the connecting hole 26 and the channel 16 together form irregularly shaped channels, which are difficult to be completely blocked, thereby improving the reliability of the drainage tube.

[0053] The inlet end 7 of the drainage tube can extend into the anti-clogging bracket by 0.8 cm to 1.2 cm, preferably 1 cm. The extension length is less than or equal to the length of the perforated area 18. The three-dimensional drainage holes 6 on the perforated area 18 can be all located in the collection chamber, or a part of the three-dimensional drainage holes can be left behind the anti-clogging bracket. In other words, the three-dimensional drainage holes can be located at the connection seat 21 (see Figure 5 ) on both sides, so that the drainage tube can simultaneously attract lymph fluid in the collecting cavity and behind the anti-clogging stent, reducing the leakage of lymph fluid in the collecting cavity.

[0054] Figure 5 It is a three-dimensional diagram of the inner groove section extending into the anti-blocking bracket.

[0055] As an optional embodiment, the anti-blocking bracket 5 can be a frame spherical structure, and a large gap is formed between the frames of the anti-blocking bracket 5, which can provide a channel for the open ends of the lymph nodes and deep cervical lymphatic vessels to enter the anti-blocking bracket 5. The anti-blocking bracket 5 has a certain rigidity, which can prevent the surrounding fat or muscle tissue from squeezing the inlet end 7, reducing the tube diameter, and causing poor drainage or blockage.

[0056] Optionally, the anti-blocking bracket 5 may include a frame unit 19 and a connecting seat 21. One end of the frame unit is connected to the connecting seat, the frame unit extends in a curved manner along the axial direction of the connecting seat, a plurality of frame units are arranged and distributed along the circumferential direction of the connecting seat, the frame unit surrounds and forms a collection cavity, and the connecting seat is fixedly connected to the drainage tube. The connecting seat 21 may be annular, and the connecting seat 21 is fixedly sleeved on the outside of the inlet end 7. As an optional embodiment, a through hole for the drainage tube to pass through may be provided at the center of the connecting seat 21, and the connecting seat 21 is fixedly connected to the outside of the inner groove segment outer wall 14 through the through hole, so that the relative position of the inner groove segment 17 and the anti-blocking bracket 5 is fixed, so that the part of the inner groove segment 17 extending into the anti-blocking bracket 5 is fixed, and the structural stability is strong, which is conducive to continuously drawing out lymph fluid from the inside of the anti-blocking bracket 5. The frame unit contacts the side wall of the collection cavity, and the lymph fluid and tissue fluid can flow through the connecting seat along the frame unit and be sucked in by the three-dimensional drainage hole in front of or behind the connecting seat, thereby improving the collection efficiency. The radial dimension of the connecting seat is related to the radial dimension of the anti-clogging support frame and needs to be determined according to the size of the collecting chamber.

[0057] The fixed connection methods between the connection seat 21 and the outer wall 14 of the inner groove section include but are not limited to screw connection and clamping connection. Figure 5The figure does not show the human tissues wrapped around the anti-blocking stent 5 after it is implanted into the human body. In fact, the human tissues such as fat and muscle surrounding the anti-blocking stent 5 are propped up by the anti-blocking stent 5, and a collecting cavity 22 is formed inside the anti-blocking stent 5. Lymphatic fluid is secreted and flows out from lymphatic tissues such as lymph nodes and the open ends of deep cervical lymphatic vessels, and is collected in the collecting cavity 22, and then sucked into the drainage tube from the inlet end 7. The reason for using a drainage device with an anti-blocking stent 5 to collect cervical lymph is that the existing lymphatic drainage device is suitable for draining lymphatic fluid from lymphatic vessels with a diameter of about 4 mm such as the thoracic duct by puncture, while the lymphatic drainage device of the present invention is used to drain lymphatic fluid from deep cervical lymphatic vessels. Since the deep cervical lymphatic vessels are only 0.2 mm in diameter, the existing lymphatic drainage equipment cannot drain them continuously and constantly. Therefore, the present invention creatively props up the collecting cavity 22 by the anti-blocking stent 5, manufactures the open ends of deep cervical lymphatic vessels by surgical methods, and places the open ends of the lymphatic vessels and the nearby lymph nodes in the collecting cavity. After the lymphatic tissue secretes lymph and collects in the collection cavity 22, it is collected and discharged by the lymphatic drainage device of the present invention.

[0058] Figure 6 A front view of the anti-blocking bracket.

[0059] As an optional embodiment, the material of the anti-blocking bracket can be a shape memory alloy. The shape memory alloy is a metal with a certain shape memory ability. When the temperature is low, the alloy product is easy to deform and can be bent into other shapes. When the temperature rises to a certain value, the alloy product will restore elasticity and automatically unfold. Therefore, the anti-blocking bracket 5 has the characteristics of being retractable and deformable. The anti-blocking bracket at the lower and higher temperatures mentioned above has a folded state 23 and a restored state 24 respectively. The anti-blocking bracket in the folded state can reduce the size and maintain the shape by folding, and the anti-blocking bracket in the restored state can automatically restore the stretched shape.

[0060] As an optional embodiment, the shape memory alloy material used in the stent is specially configured so that the anti-blocking stent has the following properties: that is, when it is in a restored state close to the body temperature, the stent has good rigidity and a supporting function, and can maintain the collection cavity 22 (see Figure 1 ) shape; the anti-blockage stent is in a folded state when it is lower than the temperature close to the body temperature, and the temperature should not be too low at this time to avoid frostbite or irritation when implanted in the body. The anti-blockage stent in this embodiment can be folded into a shape with a smaller radial dimension at the temperature corresponding to the folded state; after being placed in the body, due to the increase in ambient temperature, the temperature of the anti-blockage stent rises to close to the body temperature, and it will automatically restore the stretched shape, thereby achieving the purpose of minimizing the surgical incision. Figure 5 A form of the anti-blockage stent being stretched out is shown, which is embodied as an open mesh stent structure.

[0061] Specifically, the frame unit 19 in the folded state 23 can be folded into Figure 6 The state shown by the dotted line is that it extends along the axial direction of the drainage tube, so that the radial size of the anti-blockage stent 5 at this time is smaller; the frame unit 19 in the restored state 24 will be restored to the state shown by the solid line in the figure. At this time, the frame unit 19 is bent into an arc or U shape, and the radial size of the anti-blockage stent 5 is increased. A plurality of frame units 19 together form a spherical anti-blockage stent 5. The frame unit 19 in the restored state 24 has a certain rigidity, so that the anti-blockage stent 5 can withstand the pressure of the external surrounding fat or muscle tissue. The anti-blockage stent 5 composed of the frame unit 19 in the folded state 23 has a smaller radial size, and the wound size required for implantation in the human body is also smaller, which is not only easier to implant into the patient's body, but also the wound recovery speed is faster and more beautiful.

[0062] The specific operation method of the lymphatic drainage device of the present invention during implantation is as follows:

[0063] S1. After general anesthesia takes effect, the patient lies in supine position with the head slightly tilted to the opposite side, and the neck, chest and abdomen are disinfected and covered with a drape;

[0064] S2, make a 5 cm oblique incision along the medial edge of the sternocleidomastoid muscle and slightly outward, cut the platysma muscle, and protect the cervical plexus branches;

[0065] S3, pull the sternocleidomastoid muscle outward, separate the fat tissue, and find the internal jugular vein;

[0066] S4, the accessory nerve is found along the direction of the jugular foramen at the mandibular angle;

[0067] S5. Lymph nodes in zone II were found between the internal jugular vein and accessory nerve, and multiple deep cervical lymphatic vessels were found using markers such as indocyanine green.

[0068] S6. Open the deep cervical lymphatic vessels, either by transverse cutting or longitudinal lateral wall cutting, or by cutting the distal lateral wall of the lymph node;

[0069] S7, placing the anti-blocking stent 5 at the open end of the deep cervical lymphatic vessel that has been pre-treated by surgical operation, the open end of the lymphatic vessel is located in the stent mesh cavity, and the stent mesh is sutured and fixed with the surrounding fascia;

[0070] S8, the head end of the drainage tube 1 extends about 1 cm into the anti-blocking bracket 5, adjacent to the lymphatic vessel with the open end mentioned above, and the pressure sensor 4 is placed;

[0071] S9. Make a 2-3 cm incision in the front of the chest wall, use a trocar or subcutaneous cleaning rod to establish a subcutaneous route, and lead the drainage tube 1 to the chest;

[0072] S10, placing an implantable peristaltic pump and an implantable power supply device 3, fixing them under the chest skin with a non-absorbable suture, and connecting the signal line of the pressure sensor 4;

[0073] S11. Use a trocar or standard open surgery to place the abdominal end of drainage tube 1 in the abdominal cavity. Finally, you can choose to place it freely in the abdominal cavity, or use non-absorbable sutures to fix the catheter to the posterior wall of the rectus abdominis muscle, or use a transpubic bladder incision at the end. After exposing the bladder, make a 1 cm small incision to insert the abdominal end of drainage tube 1, and then suture the bladder and skin.

[0074] S12, flush the drainage tube 1 with 5 ml of normal saline to ensure that the drainage device is unobstructed;

[0075] S13, rinse and close the wound, the operation is complete, and the patient wakes up and returns to the ward safely;

[0076] S14. Inform patients of precautions.

[0077] The technical scope of the present invention is not limited to the contents of the above description. Those skilled in the art can make various deformations and modifications to the above implementation without departing from the technical idea of ​​the present invention, and these deformations and modifications should all fall within the scope of the present invention.

Claims

1. A lymphatic drainage device, characterized in that: The lymphatic drainage device comprises: An anti-clogging support (5), wherein a collecting cavity (22) is formed inside the anti-clogging support (5), the anti-clogging support (5) is used to support biological tissues around the location to be drained so as to maintain the shape of the collecting cavity (22), and the collecting cavity (22) is used to collect lymph fluid produced by lymphatic tissues around the location to be drained; A drainage tube (1), wherein two ends of the drainage tube (1) are an inlet end (7) and an outlet end (8), the inlet end (7) is used to introduce lymph fluid into the drainage tube (1), the outlet end (8) is used to guide lymph fluid out of the drainage tube (1), and the inlet end (7) extends into the collecting cavity (22); and An implantable pump (2), the implantable pump (2) being connected to the drainage tube (1) and being used to pump lymph fluid in the collection chamber (22) into the drainage tube (1) from the inlet end (7) and out from the outlet end (8); The anti-clogging support (5) comprises a frame unit (19) and a connecting seat (21), one end of the frame unit (19) is connected to the connecting seat (21), the frame unit (19) extends in a curved manner along the axial direction of the connecting seat (21), a plurality of the frame units (19) are arranged and distributed along the circumferential direction of the connecting seat (21), the frame units (19) surround and form the collecting cavity (22), the connecting seat (21) is fixedly connected to the drainage tube (1), and gaps are formed between the frame units (19), which provide a passage for the open ends of lymph nodes and lymphatic vessels in the deep neck to enter the anti-clogging support (5).

2. The lymphatic drainage device according to claim 1, characterized in that: The drainage tube (1) comprises an inner groove section (17) starting from the inlet end (7), the inner groove section (17) comprising an inner groove section outer wall (14) and a partition (15) connected to the inner side of the inner groove section outer wall (14), the partition (15) being used to divide the interior of the inner groove section (17) into a plurality of channels (16), the inner groove section (17) having a length of 2.5 cm to 3.5 cm, and the inlet end (7) of the drainage tube (1) extending into the anti-clogging bracket (5) by 0.8 cm to 1.2 cm.

3. The lymphatic drainage device according to claim 2, characterized in that: The partition plate (15) extends along the axial direction of the inner groove section (17), so that the axes of the plurality of channels (16) are parallel to each other.

4. The lymphatic drainage device according to claim 3, characterized in that: The cross-sectional shape of the partition plate (15) is an I-shape, a square, a triangle, a well-shape or an arc triangle, and the interior of the inner groove section (17) is divided into 5, 5, 4, 9 and 4 channels (16) respectively.

5. The lymphatic drainage device according to claim 2, characterized in that: A perforated area (18) starting from the inlet end (7) is provided on the outer wall (14) of the inner groove section, the perforated area (18) comprising a plurality of three-dimensional drainage holes (6) connecting the channel (16) and the collection chamber (22), and the length of the perforated area (18) is 1.2 cm to 1.8 cm.

6. The lymphatic drainage device according to claim 2, characterized in that: A plurality of communication holes (26) are provided on the partition plate (15), and the communication holes (26) are used to connect the plurality of channels (16) to each other.

7. The lymphatic drainage device according to claim 1, characterized in that: The length of the drainage tube (1) is greater than 50 centimeters and less than 100 centimeters.

8. The lymphatic drainage device according to claim 1, characterized in that: The anti-clogging bracket (5) has an umbrella shape, a polyhedron shape, a sphere shape or an ellipsoid shape.

9. The lymphatic drainage device according to claim 1, characterized in that: The material of the anti-blockage bracket (5) is a shape memory alloy. The anti-blockage bracket (5) has a folded state and a restored state. In the folded state, the anti-blockage bracket (5) can be reduced in size by folding, and in the restored state, the anti-blockage bracket (5) can automatically restore its stretched shape.

10. The lymphatic drainage device according to claim 1, characterized in that: The implantable pump (2) is a unidirectional peristaltic pump, which continuously pumps the liquid in the drainage tube (1) from the inlet end (7) to the outlet end (8) in a unidirectional manner.

11. The lymphatic drainage device according to claim 1, characterized in that: The implantable pump (2) comprises: An implantable power supply device (3), the power supply device (3) being electrically connected to the implantable pump (2) to continuously supply power to the implantable pump (2); and A pressure sensor (4), the pressure sensor (4) is used to measure the pressure in the drainage tube (1), the power supply device (3) adjusts the negative pressure of the implantable pump (2) according to the measurement signal of the pressure sensor (4), the pressure sensor (4) is fixed on the drainage tube (1), and the wall of the drainage tube (1) at the fixed position of the pressure sensor (4) is thinner than the wall of the drainage tube (1) at other positions.

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