Horizontal rotor centrifugal machine capable of eliminating wall effect

By introducing a support device or pulling device into the horizontal rotor centrifuge, the angle between the center line of the bucket and the rotation axis is automatically adjusted, and the problem of wall effect is solved, achieving more uniform material settlement and better cell activity protection.

CN119702265APending Publication Date: 2025-03-28王泾汝
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Patent Information

Application Number
CN202411897049.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-23
Publication Date
2025-03-28

AI Technical Summary

Technical Problem

When the existing horizontal rotor centrifuge rotates, the wall effect is not perpendicular to the rotation axis, which affects the separation effect. Especially when centrifuge active substances such as cells, it will cause the cells to move and settle close to the wall of the centrifuge tube, affecting cell activity and uneven distribution.

Method used

A horizontal rotor centrifuge including a support device or pulling device is designed to monitor the rotation speed of the centrifuge rotation shaft through a rotary detection assembly. When the required speed for centrifugation is reached, the support device or pulling device is automatically activated to provide support or pulling force to the bucket, so that the center line of the bucket remains perpendicular or close to the rotation shaft.

Benefits of technology

It effectively eliminates the wall effect during centrifugation, so that the substances that need to be separated in the centrifuge tube evenly settle to the bottom of the centrifuge tube, improving the separation effect of the centrifuge and protecting the activity of the cells.

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Abstract

The invention relates to the technical field of centrifugal machines, in particular to a horizontal rotor centrifugal machine capable of eliminating wall effect, which comprises a centrifugal machine body, and a bucket, a centrifugal machine rotating shaft and a hanger which are arranged in the centrifugal machine body, and further comprises a rotating detection assembly and a support device or a traction device which are arranged in the centrifugal machine body, when the rotating detection assembly monitors that the rotating speed of the rotating shaft of the centrifugal machine reaches the speed required by centrifugation, the rotating detection assembly starts the supporting device or the traction device to automatically provide a certain supporting force or pulling force for the centrifugal machine bucket, so that the bucket deflects upwards by a certain angle; therefore, the center line of the centrifugal bucket is kept vertical or approximately vertical to the rotating shaft in the centrifugal process. According to the centrifugal tube, substances needing to be separated in the centrifugal tube can uniformly settle to the bottom of the centrifugal tube, and the wall effect during centrifugation is completely eliminated.
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Description

Technical Field

[0001] The invention relates to the technical field of centrifuges, and in particular to a horizontal rotor centrifuge capable of eliminating wall effects. Background Art

[0002] Horizontal rotor centrifuge is a device that uses centrifugal force to separate mixtures. Its working principle is to use the centrifugal force generated by rotation to separate different substances in the mixture into layers according to their density and mass differences, thereby achieving the purpose of separation. It is widely used in biomedicine, chemistry, food, agriculture and other fields.

[0003] At present, the bucket of the horizontal rotor centrifuge on the market is directly hung on the centrifuge rotating shaft bracket, without other components to provide support. When the rotating shaft rotates the bucket through the bracket, it cannot provide additional support to make the bucket deflect upward. The center line of the centrifuge bucket cannot be perpendicular to the rotating shaft, and there will be a certain angle, such as Figure 1 As shown. The inventors found that the existence of this angle will cause the wall effect during centrifugation, thereby affecting the separation effect of the centrifuge. At the same time, the heavier the bucket and the centrifuge tube, the slower the centrifugal speed, and the larger this angle will be. If active substances, such as cells, are centrifuged, the wall effect will cause the cells to move and settle close to the wall of the centrifuge tube, affecting the cell activity and causing uneven distribution of cells when they gather at the bottom of the centrifuge tube. Summary of the invention

[0004] In order to solve the above problems, the present invention provides a horizontal rotor centrifuge in which the center line of the bucket and the rotation axis can be adaptively vertical during rotation, thereby eliminating the wall effect.

[0005] To achieve the above object, the technical solution adopted by the present invention is:

[0006] A horizontal rotor centrifuge capable of eliminating wall effect comprises a centrifuge body, a bucket installed in the centrifuge body, a centrifuge rotating shaft, and a hanger. It also comprises a supporting device or a pulling device and a rotation detection component installed in the centrifuge body. When the rotation detection component monitors that the rotation speed of the centrifuge rotating shaft reaches the speed required for centrifugation, the rotation detection component starts the supporting device or the pulling device to automatically provide a certain supporting force or pulling force to the centrifuge bucket, so that the bucket deflects upward by a certain angle, thereby keeping the center line of the centrifuge bucket and the rotating shaft vertical or nearly vertical during the centrifugation process.

[0007] Furthermore, the rotation detection component includes but is not limited to a rotation speed sensor.

[0008] Furthermore, the supporting device is installed on a rotating shaft or a bracket, and includes a supporting rod and a supporting rod driving member.

[0009] Furthermore, the rotation detection assembly is installed at the lower end of the rotating shaft of the centrifuge.

[0010] Furthermore, the pulling device is used to apply pulling force to the bucket at the connection between the bucket and the hanger to make the bucket level.

[0011] The invention can automatically provide a certain supporting force or pulling force to the centrifuge bucket during centrifugal rotation, so that the bucket deflects upward by a certain angle, thereby making the center line of the centrifuge bucket and the rotating axis remain vertical or nearly vertical during the centrifugal process, thereby making the substances to be separated in the centrifuge tube evenly settle to the bottom of the centrifuge tube, and completely eliminating the wall effect during centrifugation. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Other features, objects and advantages of the present invention will become more apparent from the detailed description of non-limiting embodiments made with reference to the following drawings:

[0013] Figure 1 This is a diagram of the rotation state of a commercially available horizontal rotor centrifuge.

[0014] Figure 2 It is a schematic diagram of the structure of the rotor in a stationary state when the supporting structure is connected to the rotating shaft of the centrifuge.

[0015] Figure 3 It is a schematic diagram of the structure of the rotor rotating state when the supporting structure is connected to the rotating shaft of the centrifuge.

[0016] Figure 4 This is a schematic diagram of the structure of the rotor in a stationary state when the supporting structure is connected to the bracket.

[0017] Figure 5 It is a structural schematic diagram of the rotor rotating state when the supporting structure is connected to the bracket.

[0018] Figure 6 This is a schematic diagram of the structure of the rotor in a stationary state when the pulling structure is connected to the bracket.

[0019] Figure 7 The traction structure is connected to the bracket and the rotor is in a rotating state.

[0020] Figure 8 A structural diagram of an embodiment of the supporting device in the present invention;

[0021] Fig. 9 is a structural schematic diagram of the supporting device when it is in a supporting state;

[0022] Fig.10 A structural diagram of an embodiment of pulling and transposing the support device in the present invention;

[0023] Fig.11It is a schematic diagram of the structure when pulling and transposing the pulling bucket;

[0024] In the figure: 1-centrifuge body; 2-bucket center line; 3-centrifuge rotation axis; 4-hanging rack; 5-bucket; 6-support device; 7-rotation detection assembly; 8-pulling mechanism; 9-upper gear bar; 10-bucket hanging shaft fixed gear; 11-lower gear bar; 12-support rod fixed gear; 13-left gear bar; 14-support rod; 15-right gear bar; 16-support drive gear. DETAILED DESCRIPTION

[0025] The present invention is described in detail below in conjunction with specific embodiments. The following embodiments will help those skilled in the art to further understand the present invention, but are not intended to limit the present invention in any form. It should be noted that, for those of ordinary skill in the art, several variations and improvements may be made without departing from the concept of the present invention. These all belong to the protection scope of the present invention.

[0026] Example 1

[0027] like Figure 2-Figure 5 As shown, a horizontal rotor centrifuge that can eliminate the wall effect according to an embodiment of the present invention comprises a centrifuge body 1 and two buckets 5 installed in the centrifuge body 1, a centrifuge rotating shaft 3, a rack 4, a supporting device 6 and a rotating detection assembly 7. The two buckets 5 are rotatably symmetrically installed at both ends of the rack 4 through the rotating shaft, and are located on both sides of the upper end of the centrifuge rotating shaft 3. The centrifuge rotating shaft 3 and the rack 4 adopt an existing fixed locking connection method. The rotating detection assembly 7 is installed at the lower end of the centrifuge rotating shaft 3 or any position in the centrifuge body 1, and is used to monitor the rotating speed of the centrifuge rotating shaft 3, and to evaluate the rotating speed of the centrifuge rotating shaft 3 based on the preset required centrifugal speed. When the rotating detection assembly 7 detects that the rotating speed of the centrifuge rotating shaft 3 reaches the required centrifugal speed, the rotating detection assembly 7 starts the supporting device 6, automatically provides a certain supporting force to the centrifuge bucket, so that the bucket deflects upward by a certain angle, thereby making the center line of the centrifuge bucket and the rotating shaft remain vertical or nearly vertical during the centrifugation process, so that the substances to be separated in the centrifuge tube are evenly settled to the bottom of the centrifuge tube, and the wall effect during centrifugation is completely eliminated.

[0028] In this embodiment, the rotation detection assembly 7 includes but is not limited to a rotation speed sensor. The support device is installed on the rotating shaft or the bracket, and includes a support rod and a support rod driving member.

[0029] In this embodiment, the support device 6 is used to apply additional upward support force to the centrifuge bucket during centrifugation, so that the center line of the centrifuge bucket is perpendicular or nearly perpendicular to the rotation axis. This structure can be achieved by an additional structure on the rotation axis, an additional structure on the bracket, or other structural devices by applying support force to the bucket. Figure 8-Figure 9 The structural diagram of an embodiment of the support device is shown in FIG. The support device can be installed on the bracket or outside the bracket, and is composed of a support rod fixed gear 12, a left gear bar 13, a support rod 14, a right gear bar 15, and a support drive gear 16. When the centrifuge reaches the required speed, the detection mechanism starts the support device drive mechanism to drive the gear to rotate, and the left and right gear bars drive the support rod fixed gear to rotate a certain angle and then fix it, driving the bucket to deflect to a certain extent, so that the center line of the bucket and the rotation axis are perpendicular or nearly perpendicular.

[0030] Example 2

[0031] like Figure 6-Figure 7 As shown, a horizontal rotor centrifuge that can eliminate the wall effect according to an embodiment of the present invention includes a centrifuge body 1 and two buckets 5 installed in the centrifuge body 1, a centrifuge rotating shaft 3, a hanger 4, a pulling mechanism 8 and a rotation detection assembly 7. The two buckets 5 are rotatably and symmetrically installed at the two ends of the hanger 4 through the rotating shaft, and are located on both sides of the upper end of the centrifuge rotating shaft 3. The centrifuge rotating shaft 3 and the hanger 4 adopt an existing fixed locking connection method. The rotation detection assembly 7 is installed at the lower end of the centrifuge rotating shaft 3 or any position in the centrifuge body 1, and is used to monitor the rotation speed of the centrifuge rotating shaft 3, and to evaluate the rotation speed of the centrifuge rotating shaft 3 based on the preset required centrifugal speed. When the rotation detection assembly 7 detects that the rotation speed of the centrifuge rotating shaft 3 reaches the required centrifugal speed, the rotation detection assembly 7 starts the pulling mechanism 8, automatically provides a certain pulling force to the centrifuge bucket, so that the bucket deflects upward by a certain angle, thereby making the center line of the centrifuge bucket and the rotating shaft remain vertical or nearly vertical during the centrifugation process, so that the substances to be separated in the centrifuge tube are evenly settled to the bottom of the centrifuge tube, and the wall effect during centrifugation is completely eliminated.

[0032] In this embodiment, the pulling device is used to apply pulling force to the bucket at the connection between the bucket and the hanger to make the bucket level. Figure 10-11As shown, it is an embodiment diagram of a pulling device. The pulling device can be arranged on the hanger or outside the hanger, and is composed of a pulling drive mechanism and a gear 17, an upper gear bar 9, a bucket hanging shaft fixed gear 10 and a lower gear bar 11; when the rotating shaft rotates to drive the bucket to rotate, the structure on the pulling transpose does not take effect. When the centrifuge reaches the required speed, the detection mechanism starts the pulling device drive mechanism to drive the gear to rotate, and drives the gear connected to the bucket hanging shaft fixed gear (in this example, the bucket hanging shaft is fixed on the bucket) through the upper and lower gear bars to rotate a certain angle and then fixed, driving the bucket to deflect a certain amount, so that the center line of the bucket and the rotating axis are perpendicular or nearly perpendicular.

[0033] The present invention eliminates the wall effect by reducing the angle between the center line of the centrifuge bucket and the rotation axis. Any method that can change the angle between the center line of the bucket and the rotation axis during centrifugation, such as providing pulling force, supporting force or rotational force to the bucket, so that the center line of the centrifuge bucket and the rotation axis are vertical or nearly vertical, falls within the protection scope of the present invention.

[0034] The above describes the specific embodiments of the present invention. It should be understood that the present invention is not limited to the above specific embodiments, and those skilled in the art may make various modifications or variations within the scope of the claims, which do not affect the essence of the present invention.

Claims

1. A horizontal rotor centrifuge capable of eliminating wall effect, comprising a centrifuge body, a bucket installed in the centrifuge body, a centrifuge rotating shaft, and a rack, characterized in that: It also includes a rotation detection component, a supporting device or a pulling device installed in the centrifuge body. When the rotation detection component monitors that the rotation speed of the centrifuge rotating shaft reaches the speed required for centrifugation, the rotation detection component starts the supporting device or the pulling device to automatically provide a certain supporting force or pulling force to the centrifuge bucket, so that the bucket deflects upward by a certain angle, thereby keeping the center line of the centrifuge bucket and the rotating shaft vertical or nearly vertical during the centrifugation process.

2. A horizontal rotor centrifuge capable of eliminating wall effect as claimed in claim 1, characterized in that: The rotation detection component includes but is not limited to a rotation speed sensor.

3. A horizontal rotor centrifuge capable of eliminating wall effect as claimed in claim 1, characterized in that: The supporting device is installed on the rotating shaft or the hanging bracket, and comprises a supporting rod and a supporting rod driving member.

4. A horizontal rotor centrifuge capable of eliminating wall effect as claimed in claim 1, characterized in that: The rotation detection assembly is installed at the lower end of the rotating shaft of the centrifuge.

5. A horizontal rotor centrifuge capable of eliminating wall effect as claimed in claim 1, characterized in that: The pulling device is used to apply pulling force to the bucket at the connection between the bucket and the hanging bracket to make the bucket level.