Pyroxasulfone-isoproturon suspending agent as well as preparation method and application thereof

Abstract

The invention relates to the technical field of pesticides, in particular to a pyroxasulfone and isoproturon suspending agent and a preparation method and application thereof.The pyroxasulfone and isoproturon suspending agent is prepared from, by weight, 5%-10% of pyroxasulfone raw medicine, 30%-50% of isoproturon raw medicine, 10%-15% of wetting dispersant, 0.3%-1.5% of anti-precipitation thickener, 3%-5% of antifreezing agent, 0.01%-0.5% of defoaming agent, 0.01%-0.2% of bactericide and the balance deionized water, and meanwhile, the sanding efficiency, the heat storage stability, the cold storage stability and the wetting spreadability of the product are guaranteed, and the actual application requirements are better met.

Description

Technical Field

[0001] The invention relates to the technical field of pesticides, in particular to a sulfonepyraclostrobin·isoproturon suspension, and a preparation method and application thereof. Background Art

[0002] Sulfonepyraclostrobin is a new type of broad-spectrum, highly active pre-emergence soil treatment agent developed by Kumizu Chemical Co., Ltd. of Japan. It belongs to the isoxazole herbicide. After application, it is absorbed by the young roots and shoots of weeds, inhibiting the early growth of seedlings, destroying meristems and coleoptiles, and is a serious potential inhibitor of VLCFA (very long side-chain fatty acids) (C20-C30) biosynthesis in plants; it mainly inhibits the activity of photosystem II by blocking the electron flow between the primary receptor (QB binding site of D1 protein) and the secondary receptor (plastoquinone) in photosystem II, resulting in the production of reactive oxygen species (ROS) in plants, thereby inhibiting the production of ATP and NADPH2. At present, the compound preparations of sulfonepyraclostrobin and isoproturon mainly focus on improving the weed control effect of crops. For example, a Chinese patent (authorization announcement number CN116158442B) discloses a composition comprising sulfonepyraclostrobin and isoproturon, and a Chinese patent application (publication number CN108293988A) provides a herbicidal composition comprising sulfonepyraclostrobin and its use. Although the surface tension of the drug solution and the contact angle between the drug solution and the weed leaf surface can be effectively reduced to a certain extent by optimizing the adjuvant combination, in actual application, the water dispersion effect of the preparation needs to be further improved, and the stability of the preparation under high and low temperature conditions also needs to be further improved. Summary of the invention

[0003] On one hand, the present invention provides a sulfonepyraclostrobin·isoproturon suspension, which comprises, by weight percentage, 5-10% of sulfonepyraclostrobin technical, 30-50% of isoproturon technical, 10-15% of wetting dispersant, 0.3-1.5% of anti-precipitation thickener, 3-5% of antifreeze, 0.01-0.5% of defoamer, 0.01-0.2% of bactericide, and the balance is made up of deionized water.

[0004] As a preferred technical solution, the mass ratio of sulfonepyraclostrobin technical and isoproturon technical is 1:(4-6), preferably 1:5. Based on the system of the present invention, sulfonepyraclostrobin and isoproturon are used as effective active ingredients, especially controlling the mass ratio of sulfonepyraclostrobin and isoproturon to be 1:(4-6) has a good synergistic effect. Under the action of specific wetting and dispersing agents, anti-precipitation thickeners and other additives, the provided sulfonepyraclostrobin·isoproturon suspension product has excellent control effect on crop weeds, can meet the demand for annual weed control in winter wheat fields, and the control effect is less affected by the environment.

[0005] As a preferred technical solution, the wetting dispersant at least includes a weak cationic polycarboxylic acid dispersant, a rosin ether modified material dispersant, and a block copolymer dispersant.

[0006] As a preferred technical solution, the weak cationic polycarboxylic acid dispersant is SP-SC3275 (Qingyu auxiliary agent).

[0007] As a preferred technical solution, the rosin ether modified material dispersant is SP-SC3 (Qingyu auxiliary agent).

[0008] As a preferred technical solution, the block copolymer dispersant at least includes EO / PO block polyether (a block copolymer composed of EO (ethylene oxide) and PO (propylene oxide)) and polyethylene / polypropylene block copolymer.

[0009] Preferably, the average molecular weight of the EO / PO block polyether is 2000-4000, preferably Ethylan Ns-5001q (Nolyon).

[0010] Preferably, the polyethylene / polypropylene block copolymer is EZ TABS (Lamberti).

[0011] As a preferred technical solution, the mass ratio of the weak cationic polycarboxylic acid dispersant, the rosin ether modified dispersant, the EO / PO block polyether, and the polyethylene / polypropylene block copolymer is 3:3:2:(1-8), preferably 3:3:2:(3-6), and most preferably 3:3:2:5.

[0012] The suspension product provided by the present invention, in order to ensure the prevention effect, optimizes the ratio of sulfonepyraclostrobin and isoproturon original medicine while controlling the total addition amount of sulfonepyraclostrobin original medicine and isoproturon original medicine in the product to be ≥40wt%, which greatly increases the difficulty of controlling the stability of the product and affects the sand milling efficiency to a certain extent. The present invention adopts conventional carboxylate dispersant in combination with naphthalenesulfonate condensate and phosphate as an auxiliary agent system in the early stage. Although the heat storage and cold storage stability of the prepared product can be effectively controlled, the sand milling efficiency is low, the wetting and spreading property is poor, the preparation is dispersed in water in a mass shape, and the dispersion effect is not good. In order to improve the above-mentioned problems and enable the provided product to have a corresponding soil sealing effect, the product system is optimized to introduce synergist lignin and naphthalenesulfonate condensate in combination with phosphate, weak cationic polycarboxylic acid dispersant, rosin ether modified material dispersant, and block copolymer dispersant to prepare the suspension product. Although the wetting and spreading property and sand milling efficiency of the product can be effectively improved, the heat storage stability of the product is damaged, and the phenomenon of bottoming, reduced suspension rate or precipitate in screening after hot storage cannot meet the actual application requirements. The invention is based on an unexpected discovery during the screening process of a large number of additives. By simultaneously introducing a weak cationic polycarboxylic acid dispersant, a rosin ether modified material dispersant, and a block copolymer dispersant, especially when the block copolymer dispersant at least includes EO / PO block polyether and polyethylene / polypropylene block copolymer, under the coordinated effect of other raw materials in the system, the sand grinding efficiency, heat storage stability, cold storage stability, and wetting and spreading properties of the product are simultaneously guaranteed, thereby better meeting the actual application requirements.

[0013] As a preferred technical solution, the antifreeze agent at least includes ethylene glycol.

[0014] As a preferred technical solution, the anti-sedimentation thickener includes at least magnesium aluminum silicate and xanthan gum.

[0015] Preferably, the mass ratio of the magnesium aluminum silicate to xanthan gum is (8-12):1, preferably 10:1.

[0016] As a preferred technical solution, the defoamer includes at least an organosilicon defoamer, and the organosilicon defoamer is preferably SAG 1572 (Momentive additive).

[0017] Furthermore, the present invention controls the amount of the anti-precipitation thickener added in the suspension product system and the selection and matching of the anti-precipitation thickener, especially adopts magnesium aluminum silicate and xanthan gum with a mass ratio of (8-12):1 as the anti-precipitation thickener, and matches the wetting dispersant system in the system to obtain a suspension product with low viscosity, good water dispersibility, and good hot storage and cold storage stability.

[0018] In addition, the suspension product provided by the present invention has excellent dispersion stability at a lower dilution multiple by optimizing the product formula system and coordinating the sand grinding particle size control, and has a high suspension rate, and has anti-volatilization and anti-drift properties, and a more uniform droplet particle size. After the implementation of prevention and control, it can be evenly dispersed in the soil, assisted by good adhesion and spreadability, greatly enhancing its application in soil sealing.

[0019] As a preferred technical solution, the fungicide at least includes 1,2-benzisothiazolin-3-one (BIT).

[0020] On the other hand, the present invention provides a method for preparing a sulfonepyraclostrobin·isoproturon suspension, which comprises at least the following steps: adding deionized water, isoproturon technical, sulfonepyraclostrobin technical, a wetting dispersant, an antifreeze agent, an anti-precipitation thickener, a bactericide, and a defoaming agent into a container, stirring and mixing, and obtaining the sulfonepyraclostrobin·isoproturon suspension after shearing, dispersing, and sand milling.

[0021] As a preferred technical solution, the shear dispersion time is 3-8 minutes.

[0022] As a preferred technical solution, the sand grinding treatment time is 2-2.5h.

[0023] The suspension product provided by the present invention can control the sand-grinding particle size to be below 2.5 μm within 2-2.5 hours by optimizing the formulation of various raw materials, thereby greatly improving the production efficiency and being easy to realize large-scale industrial production and popularization and application.

[0024] The third aspect of the present invention provides an application of a sulfonepyraclostrobin·isoproturon suspension, which is applied to the prevention and control of annual grass weeds and annual broadleaf weeds in winter wheat fields. The annual grass weeds include at least: Alopecurus aequalis Sobol., Poa annua L.; the annual broadleaf weeds include at least: Stellaria media (L.) Cyr.

[0025] Beneficial Effects

[0026] 1. Based on the system of the present invention, sulfonepyraclostrobin and isoproturon are used as effective active ingredients, especially controlling the combination of sulfonepyraclostrobin and isoproturon in a mass ratio of 1: (4-6) to have a good synergistic effect. Under the action of specific wetting and dispersing agents, anti-precipitation thickeners and other auxiliary agents, the provided sulfonepyraclostrobin·isoproturon suspension product has excellent control effect on crop weeds, can meet the demand for annual weed control in winter wheat fields, and the control effect is less affected by the environment.

[0027] 2. The present invention simultaneously introduces a weak cationic polycarboxylic acid dispersant, a rosin ether modified material dispersant, and a block copolymer dispersant, especially when the block copolymer dispersant includes at least EO / PO block polyether and polyethylene / polypropylene block copolymer, and under the coordination of other raw materials in the system, the sanding efficiency, heat storage stability, cold storage stability, and wetting and spreading properties of the product are simultaneously guaranteed.

[0028] 3. The present invention controls the amount of the anti-precipitation thickener added in the suspension product system and the selection and matching of the anti-precipitation thickener, especially adopts magnesium aluminum silicate and xanthan gum with a mass ratio of (8-12):1 as the anti-precipitation thickener, and matches the wetting dispersant system in the system to obtain a suspension product with low viscosity, good water dispersibility, and good hot storage and cold storage stability.

[0029] 4. The suspension product provided by the present invention has excellent dispersion stability at a lower dilution multiple by optimizing the product formula system and coordinating the sand grinding particle size control, and has a high suspension rate, and has anti-volatilization and anti-drift, and a more uniform droplet particle size. After the implementation of prevention and control, it can be evenly dispersed in the soil, assisted by good adhesion and spreadability, greatly enhancing the application in soil sealing.

[0030] 5. The suspension product provided by the present invention can control the sand-grinding particle size below 2.5 μm within 2-2.5 hours by optimizing the formulation of various raw materials, thereby greatly improving production efficiency and facilitating large-scale industrial production and promotion and application. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 This is a comparison diagram of the soil sealing effect of the suspension agent provided in Example 1 and Comparative Example 1, in which a corresponds to Example 1 and b corresponds to Comparative Example 1.

[0032] Figure 2 This is a product state diagram of the suspension provided in Comparative Example 2 that becomes a paste after heat storage.

[0033] Figure 3 This is a comparison chart of the wetting and spreadability of the suspension concentrate products provided for Example 1 and Comparative Example 4, wherein the left side of the chart corresponds to Example 1 and the right side corresponds to Comparative Example 4.

[0034] Figure 4 This is a product status diagram of the suspension provided in Comparative Example 5 with precipitates after hot storage screening.

[0035] Figure 5 This is a product status diagram of the suspension provided in Comparative Example 7 after hot storage and the formation of bottom. DETAILED DESCRIPTION

[0036] Example 1, Comparative Examples 1-7

[0037] Example 1 of the present invention Example 1 and Comparative Examples 1-7 provide, on the one hand, a sulfonepyraclostrobin·isoproturon suspension concentrate, calculated by weight percentage, and the formula is shown in Table 1.

[0038] Table 1

[0039]

[0040]

[0041] In Table 1: the weak cationic polycarboxylic acid dispersant is SP-SC3275 (Qingyu Auxiliary). The rosin ether modified dispersant is SP-SC3 (Qingyu Auxiliary). The average molecular weight of EO / PO block polyether is 4000, Ethylan Ns-500lq (Nouryon). The polyethylene / polypropylene block copolymer is EZ TABS (Ningbodi). The silicone defoamer is SAG 1572 (Moitu Auxiliary). The carboxylate dispersant is D900 (Fangzhong Auxiliary). The lignin is WG4 (Jieshe Auxiliary). The naphthalenesulfonate condensate is Morwet D-425 (Nouryon Auxiliary). The phosphate dispersant is DS505 (Fangzhong Auxiliary).

[0042] On the other hand, Example 1 and Comparative Examples 1-7 of the present invention provide a method for preparing a sulfonepyraclostrobin·isoproturon suspension, which specifically comprises the following steps: adding deionized water, isoproturon technical, sulfonepyraclostrobin technical, wetting dispersant, antifreeze, anti-precipitation thickener, bactericide, and defoamer into a container, stirring and mixing, shearing and dispersing for 5 minutes, and sand-milling for 2 hours using a vertical sand mill to obtain a sulfonepyraclostrobin·isoproturon suspension.

[0043] Performance Testing Methods

[0044] 1. The suspension product provided in Example 1 was tested for the various physical and chemical properties in Table 2. The test basis, test result indicators and test results are shown in Table 2.

[0045] Table 2

[0046]

[0047] 2. The suspension products provided in Example 1 and Comparative Examples 1-7 were subjected to the tests in Table 3. The test results are shown in Table 3. The suspension product provided in Comparative Example 2 was paste-like after heat storage. Figure 2 For comparison of the wetting and spreading properties of the suspension products provided in Example 1 and Comparative Example 4, see Figure 3 The product state of the suspension provided in Comparative Example 5 after hot storage screening with precipitates is shown in Figure 4 The product state of the suspension provided in Comparative Example 7 after hot storage is shown in Figure 5 .

[0048] Table 3

[0049]

[0050] Note: The sand grinding efficiency in Table 3 is based on the particle size after sand grinding for 2 hours according to the preparation process of Example 1 and Comparative Examples 1-7. In the same time, the smaller the particle size, the higher the sand grinding efficiency.

[0051] 3. The soil sealing effect of the products provided in Example 1 and Comparative Example 1 was tested. The test method was: the products provided in Example 1 and Comparative Example 1 were used in the soil before wheat germination (application method and water dosage: conventional spray method, 30 liters of water per mu, and the dosage of active ingredient was 576 grams per hectare). The weed situation in the wheat planting field was checked 35 days after the application. The test results are shown in Figure 1 ,analyze Figure 1 It can be seen that the sealing effect of the suspension concentrate provided in Example 1 is obvious after use, and there are basically no weeds in the later stage (preventing weeds from germinating); while after the suspension concentrate product provided in Comparative Example 1 is used, weeds in some ditch sections still germinate, there are new weeds, and the sealing effect is worse than that of the embodiment.

[0052] 4. Conduct field efficacy tests on the suspension concentrate product provided in Example 1.

[0053] In 2023, a field efficacy test of 48% sulfamethoxazole·isoproturon suspension (Example 1) for controlling annual weeds in winter wheat fields was conducted in the Zhonglongqie wheat planting field in Danfeng Street, Shizong County, Qujing City, Yunnan Province. Control targets: annual grass weeds: Alopecurus aequalis Sobol., Poa annua L.; annual broadleaf weeds: Stellaria media (L.) Cyr.

[0054] See Table 4 for the test agents.

[0055] Table 4

[0056]

[0057] Application method and water consumption: conventional spray method, 30 liters of water per mu.

[0058] The control effect of 48% pyraclostrobin·isoproturon suspension on annual weeds in winter wheat fields (35 days after application) is shown in Table 5.

[0059] Table 5

[0060]

[0061]

[0062] See Table 6 for the fresh weight control effect of 48% pyraclostrobin·isoproturon suspension on annual weeds in winter wheat fields (95 days after application).

[0063] Table 6

[0064]

[0065]

Claims

1. A sulfonepyraclostrobin·isoproturon suspension, characterized in that: Calculated by weight percentage, it includes: 5-10% of sulfonepyraclostrobin technical, 30-50% of isoproturon technical, 10%-15% of wetting and dispersing agent, 0.3%-1.5% of anti-precipitation thickener, 3-5% of antifreeze agent, 0.01-0.5% of defoaming agent, 0.01-0.2% of bactericide, and deionized water makes up the balance.

2. The sulfonepyraclostrobin·isoproturon suspension according to claim 1, characterized in that: The mass ratio of the sulfonepyraclostrobin technical drug to the isoproturon technical drug is 1:(4-6).

3. The sulfonepyraclostrobin·isoproturon suspension according to claim 1 or 2, characterized in that: The wetting dispersant at least includes a weak cationic polycarboxylic acid dispersant, a rosin ether modified material dispersant, and a block copolymer dispersant.

4. The sulfonepyraclostrobin·isoproturon suspension according to claim 3, characterized in that: The block copolymer dispersant at least includes EO / PO block polyether and polyethylene / polypropylene block copolymer.

5. The sulfonepyraclostrobin·isoproturon suspension according to claim 4, characterized in that: The average molecular weight of the EO / PO block polyether is 2000-4000.

6. The sulfonepyraclostrobin·isoproturon suspension according to claim 5, characterized in that: The mass ratio of the weak cationic polycarboxylic acid dispersant, the rosin ether modified material dispersant, the EO / PO block polyether and the polyethylene / polypropylene block copolymer is 3:3:2:(1-8).

7. The sulfonepyraclostrobin·isoproturon suspension according to claim 6, characterized in that: The anti-sedimentation thickener at least includes magnesium aluminum silicate and xanthan gum.

8. The sulfonepyraclostrobin·isoproturon suspension according to claim 7, characterized in that: The mass ratio of the magnesium aluminum silicate to the xanthan gum is (8-12):

1.

9. A method for preparing the sulfonepyraclostrobin·isoproturon suspension concentrate according to any one of claims 1 to 8, characterized in that: Deionized water, isoproturon technical, sulfonepyrazone technical, wetting dispersant, antifreeze agent, anti-precipitation thickener, bactericide and defoamer are added into a container and stirred and mixed, and sulfonepyrazone·isoproturon suspension is obtained after shearing, dispersion and sand milling.

10. Use of the sulfonepyraclostrobin·isoproturon suspension concentrate according to any one of claims 1 to 8 for controlling annual grass weeds and annual broadleaf weeds in winter wheat fields.

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