Blood lactic acid monitoring device and method and wearable equipment

Abstract

The invention relates to the technical field of health monitoring, and particularly discloses a blood lactic acid monitoring device and method and wearable equipment. The device comprises a detection chip and a paper chip sensor coated with a chemical coating; the detection chip is used for collecting a blood lactic acid detection signal of a target user by utilizing the paper chip sensor when sweat or blood on the skin surface of the target user is in contact with the chemical coating and is subjected to chemical reaction; the device provided by the invention can realize low-cost, convenient and real-time monitoring of the blood lactic acid concentration. Compared with a traditional laboratory detection method, the real-time performance and convenience of detection are greatly improved, the tedious blood sample collection process is avoided, and more efficient training and recovery decision support is provided for athletes and coaches. Meanwhile, the design of the paper chip sensor reduces the cost, and is suitable for being widely applied to the fields of exercise training, fitness monitoring, clinical health management and the like.

Description

Technical Field

[0001] The present invention relates to the technical field of health monitoring, and in particular to a blood lactate monitoring device, method and wearable equipment. Background Art

[0002] With the development of sports science, blood lactate concentration has been widely used to assess athletes' physical fitness and fatigue status. At present, the measurement of blood lactate concentration usually relies on blood sample collection and laboratory analysis, which is complicated to operate and has poor real-time performance. In addition, most of the existing portable blood lactate detection devices rely on complex sensor systems, which have problems such as high cost, poor convenience, and insufficient real-time performance.

[0003] Therefore, it is urgent to provide a technical solution to solve the above problems. Summary of the invention

[0004] In order to solve the above technical problems, the present invention provides a blood lactate monitoring device, method and wearable device.

[0005] In a first aspect, the present invention provides a blood lactate monitoring device, the technical solution of the device is as follows:

[0006] It includes: a detection chip and a paper chip sensor coated with a chemical coating; the detection chip is used for:

[0007] When the sweat or blood on the skin surface of the target user contacts the chemical coating and a chemical reaction occurs, the paper chip sensor is used to collect the blood lactate detection signal of the target user;

[0008] The current blood lactate concentration value of the target user is determined according to the blood lactate detection signal.

[0009] The beneficial effects of a blood lactate monitoring device of the present invention are as follows:

[0010] The device of the present invention can realize low-cost, convenient and real-time blood lactate concentration monitoring. Compared with traditional laboratory detection methods, the present invention greatly improves the real-time and convenience of detection, avoids the cumbersome blood sample collection process, and provides athletes and coaches with more efficient training and recovery decision support. At the same time, the design of the paper chip sensor reduces costs and is suitable for wide application in sports training, fitness monitoring, clinical health management and other fields.

[0011] Based on the above solution, the blood lactate monitoring device of the present invention can also be improved as follows.

[0012] In an optional embodiment, the chemical coating is made of lactate oxidase.

[0013] In an optional manner, the detection chip is specifically used for:

[0014] The blood lactate detection signal is sequentially amplified, analog-to-digital converted, and data processed to obtain the current blood lactate concentration value of the target user.

[0015] In an optional manner, the detection chip is also used for:

[0016] The current blood lactate concentration value is sent to the terminal device of the target user.

[0017] In an optional manner, the detection chip is arranged inside the paper chip sensor.

[0018] In a second aspect, the present invention provides a blood lactate monitoring method, the technical solution of the method is as follows:

[0019] When the sweat or blood on the skin surface of the target user contacts the chemical coating and a chemical reaction occurs, the blood lactate detection signal of the target user is collected by using the paper chip sensor; wherein the chemical coating is coated on the paper chip sensor;

[0020] The current blood lactate concentration value of the target user is determined according to the blood lactate detection signal.

[0021] The beneficial effects of a blood lactate monitoring method of the present invention are as follows:

[0022] The method of the present invention can realize low-cost, convenient and real-time blood lactate concentration monitoring. Compared with traditional laboratory detection methods, the present invention greatly improves the real-time and convenience of detection, avoids the cumbersome blood sample collection process, and provides athletes and coaches with more efficient training and recovery decision support. At the same time, the design of the paper chip sensor reduces costs and is suitable for wide application in sports training, fitness monitoring, clinical health management and other fields.

[0023] Based on the above scheme, the blood lactate monitoring method of the present invention can also be improved as follows.

[0024] In an optional embodiment, the chemical coating is made of lactate oxidase.

[0025] In an optional manner, the step of determining the current blood lactate concentration value of the target user according to the blood lactate detection signal includes:

[0026] The blood lactate detection signal is sequentially amplified, analog-to-digital converted, and data processed to obtain the current blood lactate concentration value of the target user.

[0027] In an optional manner, the method further includes:

[0028] The current blood lactate concentration value is sent to the terminal device of the target user.

[0029] In a third aspect, the present invention provides a wearable device, which includes a blood lactate monitoring device as described in the present invention.

[0030] The above description is only an overview of the technical solution of the present invention. In order to more clearly understand the technical means of the present invention, it can be implemented according to the contents of the specification. In order to make the above and other purposes, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] The accompanying drawings are only used to illustrate the embodiments and are not to be considered as limiting the present invention. In addition, the same reference symbols are used to represent the same components throughout the accompanying drawings. In the accompanying drawings:

[0032] Figure 1 It is a structural schematic diagram of an embodiment of a blood lactate monitoring device of the present invention;

[0033] Figure 2 This is one of the schematic diagrams of the blood lactate monitoring principle;

[0034] Figure 3 This is the second schematic diagram of the blood lactate monitoring principle;

[0035] Figure 4 The figure is a flow chart of an embodiment of a method for monitoring blood lactate of the present invention. DETAILED DESCRIPTION

[0036] Exemplary embodiments of the present invention will be described in more detail below with reference to the accompanying drawings. Although exemplary embodiments of the present invention are shown in the drawings, it should be understood that the present invention can be implemented in various forms and should not be limited to the embodiments set forth herein.

[0037] Figure 1 FIG. 2 is a schematic diagram showing a structure of an embodiment of a blood lactate monitoring device provided by the present invention. Figure 1 As shown, the blood lactate monitoring device includes: a detection chip 10 and a paper chip sensor 20 coated with a chemical coating 21; the detection chip 10 is used to:

[0038] When the sweat or blood on the skin surface of the target user contacts the chemical coating 21 and a chemical reaction occurs, the paper chip sensor 20 is used to collect the blood lactate detection signal of the target user.

[0039] The target user is the user who performs blood lactate monitoring in this embodiment. The target user refers to athletes by default, and can also be applied to other people without limitation. The chemical coating 21 is made of lactate oxidase, and lactate oxidase (LOx) is the main material of the chemical coating 21. The current signal collected by the blood lactate detection signal paper chip sensor 20.

[0040] The specific process of coating the chemical coating 21 on the paper chip sensor 20 is as follows: first, the paper chip sensor 20 is immersed in a buffer solution containing an appropriate amount of a cross-linking agent (such as glutaraldehyde) for a period of time by physical adsorption and cross-linking method, then the lactate oxidase and other materials are dissolved in a buffer solution containing a small amount of a protective agent, and then the treated paper chip sensor 20 is immersed in the enzyme solution, and the lactate oxidase is fixed on the surface of the paper chip sensor 20 by physical adsorption and cross-linking under mild stirring or shaking conditions. Then, the paper chip sensor 20 is taken out, and impurities such as unbound enzymes are washed away with a buffer solution, and finally, a drying treatment is performed to obtain a paper chip sensor 20 coated with the chemical coating 21.

[0041] The principle of chemical reaction between the target user's sweat or blood on the skin surface and the chemical coating 21 is as follows: when the target user's sweat or trace blood containing lactic acid enters the area where the chemical coating 21 of the paper chip sensor 20 is located through capillary action, lactic acid undergoes an oxidation reaction under the catalysis of lactate oxidase, and lactic acid (C3H6O3) is oxidized to pyruvic acid (C3H4O3), while hydrogen peroxide (H2O2) is produced. The produced hydrogen peroxide is oxidizing and can further react with other chemical substances to produce detectable signal changes. When hydrogen peroxide diffuses to the surface of the working electrode, the following reaction occurs: H2O2→O2+2H + +2e - , this electrochemical reaction will produce a current signal (blood lactate detection signal).

[0042] The paper chip sensor 20 is also provided with a transmission module (wired transmission module or wireless transmission module) to send the collected blood lactate detection signal to the detection chip 10. In addition, in this embodiment, the detection chip 10 can also be directly arranged inside the paper chip sensor 20. When the detection chip 10 is arranged inside the paper chip sensor 20, the signal can be directly transmitted inside the paper chip sensor 20.

[0043] The current blood lactate concentration value of the target user is determined according to the blood lactate detection signal.

[0044] Among them, the current blood lactate concentration value is the blood lactate concentration value collected at the current moment, which is determined according to the size of the blood lactate detection signal (current signal). The size of the current signal is proportional to the concentration of hydrogen peroxide, and the concentration of hydrogen peroxide is related to the lactate concentration in sweat or blood. By detecting the size of the current signal (blood lactate detection signal), the current blood lactate concentration value can be indirectly calculated to achieve dynamic blood lactate monitoring.

[0045] In an optional manner, the detection chip 10 is specifically used for:

[0046] The blood lactate detection signal is sequentially amplified, analog-to-digital converted, and data processed to obtain the current blood lactate concentration value of the target user.

[0047] Among them, since the directly collected blood lactate detection signal (current signal) is usually very weak, it is necessary to amplify the signal through an amplifier to obtain an amplified current signal for subsequent processing and measurement. The amplified current signal is converted into a digital signal using an analog-to-digital converter for subsequent calculation and processing. The digital signal is converted into a blood lactate concentration value using a specific algorithm in the detection chip 10 (for example, using linear regression, polynomial fitting or other statistical methods to establish a relationship model between the current signal and the blood lactate concentration value).

[0048] It should be noted that if Figure 2 As shown, the paper chip sensor 20 ( Figure 2 The chemical coating 21 on the lactic acid detection chip in the paper chip sensor 20 is the lactic acid reaction area. When the chemical coating 21 contacts the skin surface of the target user, the paper chip sensor 20 attracts liquid to flow to the lactic acid detection area (the lactic acid detection chip in the paper chip sensor 20) on the paper chip sensor 20 through "capillary action". Figure 2 The direction of the arrow in the figure indicates the direction of the flow of sweat or blood. Figure 3 As shown, after the current signal (blood lactate detection signal) is generated in the lactate detection area, the paper chip sensor 20 transmits the current signal to the external device (data processing unit) through the wireless transmission module. Among them, the relationship between the lactate detection area and the lactate reaction area is as follows: the lactate reaction area is the core part of the lactate detection area, and the lactate reaction area focuses on the chemical reaction between blood lactate and the chemical coating 21 to generate a current signal; the lactate detection area covers a wider range, providing an environment and conditions for the lactate reaction area, and using the current signal generated by the lactate reaction area to achieve blood lactate concentration detection and data transmission through sensors and other components, the two work together to achieve dynamic blood lactate detection.

[0049] In an optional manner, the detection chip 10 is also used for:

[0050] The current blood lactate concentration value is sent to the terminal device of the target user.

[0051] The detection chip 10 may include a wireless communication module for sending the current blood lactate concentration value to the terminal device of the target user. The terminal device may be a mobile phone, a computer, a tablet, etc., and there is no limitation here.

[0052] The technical solution of this embodiment can realize low-cost, convenient and real-time blood lactate concentration monitoring. Compared with the traditional laboratory detection method, the present invention greatly improves the real-time and convenience of detection, avoids the cumbersome blood sample collection process, and provides athletes and coaches with more efficient training and recovery decision support. At the same time, the design of the paper chip sensor reduces the cost and is suitable for wide application in sports training, fitness monitoring and clinical health management.

[0053] Figure 4 FIG. 1 is a flow chart of an embodiment of a blood lactate monitoring method provided by the present invention, and the method is executed by a detection chip 10. Figure 4 As shown, the method comprises the following steps:

[0054] S1. When the sweat or blood on the skin surface of the target user contacts the chemical coating 21 and a chemical reaction occurs, the blood lactate detection signal of the target user is collected by using the paper chip sensor 20; wherein the paper chip sensor 20 is coated with the chemical coating 21;

[0055] S2. Determine the current blood lactate concentration value of the target user according to the blood lactate detection signal.

[0056] In an optional manner, the chemical coating 21 is made of lactate oxidase.

[0057] In an optional manner, S2 includes:

[0058] The blood lactate detection signal is sequentially amplified, analog-to-digital converted, and data processed to obtain the current blood lactate concentration value of the target user.

[0059] In an optional manner, the method further includes:

[0060] The current blood lactate concentration value is sent to the terminal device of the target user.

[0061] The technical solution of this embodiment can realize low-cost, convenient and real-time blood lactate concentration monitoring. Compared with the traditional laboratory detection method, the present invention greatly improves the real-time and convenience of detection, avoids the cumbersome blood sample collection process, and provides athletes and coaches with more efficient training and recovery decision support. At the same time, the design of the paper chip sensor reduces the cost and is suitable for wide application in sports training, fitness monitoring and clinical health management.

[0062] An embodiment of the present invention provides a wearable device, including a blood lactate monitoring device provided by an embodiment of the present invention.

[0063] The blood lactate monitoring device may be disposed in a wearable device (for example, the blood lactate monitoring device is fitted to the wearable device). The wearable device may be a sports bracelet or sportswear, and there is no limitation here.

[0064] The technical solution of this embodiment is based on a paper chip sensor, which adopts a wearable design. In combination with a paper chip sensor and a detection chip, it detects the blood lactate concentration on the skin surface and in the blood microcirculation, monitors the changes in lactate during exercise in real time, and provides athletes and coaches with more efficient training and recovery decision support.

[0065] In the description provided herein, a large number of specific details are described. However, it is understood that embodiments of the present invention can be practiced without these specific details. Similarly, in order to simplify the present invention and help understand one or more of the various inventive aspects, in the above description of exemplary embodiments of the present invention, the various features of the embodiments of the present invention are sometimes grouped together into a single embodiment, figure, or description thereof. Wherein, the claims that follow the specific embodiment are hereby expressly incorporated into the specific embodiment, wherein each claim itself is a separate embodiment of the present invention.

[0066] It should be noted that the above embodiments illustrate the present invention rather than limit it, and that those skilled in the art may devise alternative embodiments without departing from the scope of the appended claims. In the claims, any reference symbol between brackets shall not be construed as a limitation on the claims. The word "comprising" does not exclude the presence of elements or steps not listed in the claims. The word "one" or "an" preceding an element does not exclude the presence of a plurality of such elements. The present invention may be implemented by means of hardware comprising a number of different elements and by means of a suitably programmed computer. In a unit claim enumerating a number of devices, several of these devices may be embodied by the same hardware item. The use of the words first, second, and third, etc. does not indicate any order. These words may be interpreted as names. The steps in the above embodiments, unless otherwise specified, should not be understood as limitations on the order of execution.

Claims

1. A blood lactate monitoring device, characterized in that: include: A detection chip and a paper chip sensor coated with a chemical coating; the detection chip is used for: When the sweat or blood on the skin surface of the target user contacts the chemical coating and a chemical reaction occurs, the paper chip sensor is used to collect the blood lactate detection signal of the target user; The current blood lactate concentration value of the target user is determined according to the blood lactate detection signal.

2. The blood lactate monitoring device according to claim 1, characterized in that: The chemical coating is made of lactate oxidase.

3. The blood lactate monitoring device according to claim 1, characterized in that: The detection chip is specifically used for: The blood lactate detection signal is sequentially amplified, analog-to-digital converted, and data processed to obtain the current blood lactate concentration value of the target user.

4. The blood lactate monitoring device according to any one of claims 1 to 3, characterized in that: The detection chip is also used for: The current blood lactate concentration value is sent to the terminal device of the target user.

5. The blood lactate monitoring device according to any one of claims 1 to 3, characterized in that: The detection chip is arranged inside the paper chip sensor.

6. A blood lactate monitoring method, characterized in that: include: When the sweat or blood on the skin surface of the target user contacts the chemical coating and a chemical reaction occurs, the blood lactate detection signal of the target user is collected by using the paper chip sensor; wherein the chemical coating is coated on the paper chip sensor; The current blood lactate concentration value of the target user is determined according to the blood lactate detection signal.

7. The blood lactate monitoring method according to claim 6, characterized in that: The chemical coating is made of lactate oxidase.

8. The blood lactate monitoring method according to claim 6, characterized in that: The step of determining the current blood lactate concentration value of the target user according to the blood lactate detection signal comprises: The blood lactate detection signal is sequentially amplified, analog-to-digital converted, and data processed to obtain the current blood lactate concentration value of the target user.

9. The blood lactate monitoring method according to any one of claims 6 to 8, characterized in that: Also includes: The current blood lactate concentration value is sent to the terminal device of the target user.

10. A wearable device, characterized in that: Comprising a blood lactate monitoring device as described in any one of claims 1 to 5.

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