Electrocardio sensor prepared based on electronic skin technology and use method thereof

Abstract

The invention discloses an electrocardio sensor prepared based on an electronic skin technology and a use method thereof, and belongs to the technical field of medical monitoring devices. In order to solve the problems that traditional electrocardiogram monitoring equipment is large in size and difficult to carry, long-time continuous monitoring is difficult to achieve depending on wired equipment, and meanwhile real-time monitoring and timely early warning are difficult to achieve, the electrocardiogram sensor comprising a flexible substrate, a conductive layer, an electrocardiogram electrode, a signal processing circuit, a Bluetooth module and a packaging material is designed. The signal processing circuit controls and collects signals of the heart, conducts secondary processing on the collected signals, and sends data to a mobile device or a computer through the Bluetooth module, so that real-time monitoring of heart health is achieved. Through special material selection and process treatment, stable performance can be kept in the long-term use process, and continuous, accurate and real-time monitoring of electrocardiosignals is ensured.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical monitoring devices, and in particular relates to an electrocardiogram sensor prepared based on electronic skin technology and a method of using the same. Background Art

[0002] Cardiovascular disease is one of the diseases with the highest mortality rate in the world. ECG monitoring is a method of continuously recording and analyzing cardiac electrical activity through specific equipment. It is mainly used to evaluate the functional state of the heart and detect heart disease. It is the most direct and effective method for diagnosing such diseases. ECG monitoring can capture abnormal changes in cardiac electrical activity in a timely manner, which helps to detect heart diseases such as arrhythmia, myocardial ischemia, and myocardial infarction at an early stage. By continuously monitoring ECG changes, the severity and progression of heart disease can be assessed, providing a basis for formulating treatment plans. During treatment, ECG monitoring can help doctors understand the treatment effect and adjust drug dosage and treatment plans in a timely manner. For high-risk groups, such as patients with coronary heart disease and heart failure, ECG monitoring can provide early warning of sudden cardiac events so that timely measures can be taken. However, traditional ECG monitoring equipment is bulky and difficult to carry. It also relies on wired equipment and is difficult to achieve long-term continuous monitoring. In addition, most traditional equipment can only analyze data after the test is completed, making it difficult to achieve real-time monitoring and timely warning. There is a certain lag, which may delay the discovery and treatment of patients' conditions. Summary of the invention

[0003] In view of the problems that traditional ECG monitoring equipment is bulky, difficult to carry, and relies on wired equipment to achieve long-term continuous monitoring, as well as real-time monitoring and timely warning, the present invention provides an ECG sensor prepared based on electronic skin technology and a method of using the same, which can continuously monitor ECG signals in real time, provide timely feedback on heart health status, and provide effective assistance in the prevention and treatment of cardiovascular diseases.

[0004] In order to achieve the above object, the present invention adopts the following technical solutions:

[0005] An electrocardiogram sensor prepared based on electronic skin technology, the electrocardiogram sensor comprising a flexible substrate, a conductive layer, electrocardiogram electrodes, a signal processing circuit, a Bluetooth module and packaging materials; specifically:

[0006] Uniformly coating a conductive material on a flexible substrate to form a conductive layer;

[0007] preparing ECG electrodes at specific positions on the conductive layer;

[0008] The signal processing circuit is integrated via flexible printed circuit board technology or directly on a flexible substrate.

[0009] Furthermore, the material of the flexible substrate is selected to have good flexibility and biocompatibility; the prepolymer of the flexible substrate material and the curing agent are mixed in a certain proportion, stirred evenly, the mixed material is poured into a mold, and cured at a certain temperature to form a flexible substrate;

[0010] The conductive material is selected from metal nanowires;

[0011] The ECG electrode material is usually made of silver chloride or other materials with good conductivity and biocompatibility.

[0012] The packaging material is a material with good biocompatibility, softness and waterproof performance; the entire ECG sensor is packaged with the packaging material (such as silica gel) to protect the internal structure, while improving the biocompatibility and waterproof performance, ensuring that the packaged ECG sensor has good flexibility and durability.

[0013] Furthermore, the material of the flexible substrate is selected to have good flexibility and biocompatibility; the prepolymer of the flexible substrate material and the curing agent are mixed in a certain proportion, stirred evenly, the mixed material is poured into a mold, and cured at a certain temperature to form a flexible substrate;

[0014] The conductive material is selected from metal nanowires;

[0015] The ECG electrode material is usually made of silver chloride or other materials with good conductivity and biocompatibility.

[0016] The packaging material is a material with good biocompatibility, softness and waterproof performance; the entire ECG sensor is packaged with the packaging material (such as silica gel) to protect the internal structure, while improving the biocompatibility and waterproof performance, and ensuring the flexibility and durability of the packaged ECG sensor.

[0017] Furthermore, the signal processing circuit includes a signal acquisition module, a data processing module, a power supply and voltage stabilization module, and a data display module; the signal acquisition, data processing, power supply and voltage stabilization modules constitute the main circuit, control and acquire heart signals, perform secondary processing on the acquired signals, and send the data to a mobile device or computer through a Bluetooth module; wherein:

[0018] The signal acquisition module is composed of a preamplifier, a filter and a digital-to-analog converter. The preamplifier amplifies the weak ECG signal to increase the amplitude of the signal for subsequent processing. At the same time, the preamplifier has the characteristics of high input impedance, low noise, high common mode rejection ratio, etc., which can reduce signal distortion and interference. The preamplifier can be selected from AD620, INA128, etc.

[0019] The data processing module is composed of a microprocessor;

[0020] The power supply and voltage stabilization module is composed of a wireless charging module, a rechargeable lithium battery, a voltage stabilization chip and a charging chip;

[0021] The data display module is composed of a mobile device or a computer.

[0022] Furthermore, the filter is an active bandpass filter for removing noise and interference in the ECG signal. The filter removes noise and interference in the ECG signal to improve the quality of the signal. The filter adopts an active bandpass filter, which can be selected from UAF42, TZJH / UL8, LM358 and FI-B10T(D)-R2 series.

[0023] Furthermore, the preamplifier amplifies the ECG signal to increase the amplitude of the ECG signal.

[0024] Furthermore, the analog-to-digital converter (ADC) converts the analog ECG signal into a digital signal to facilitate digital signal processing and storage; it can be selected from ADC chips such as ADS1292 and ADS1298 that are specifically used for bioelectric signal acquisition.

[0025] Furthermore, the microprocessor further processes and analyzes the digital ECG signal, such as calculating heart rate, detecting arrhythmia, etc. A microprocessor of the ARM series and a microcontroller of the STM32 series can be selected. At the same time, a microprocessor with low power consumption and moderate speed should be required to work for 24 hours or more, and at the same time, the performance requirements of processing data should be met.

[0026] Furthermore, the Bluetooth module sends the ECG signal data packet processed by the microprocessor to a mobile device or a computer. The Bluetooth module can adopt a variety of solutions, and a Bluetooth communication module can be built from an integrated Bluetooth chip and a microstrip line antenna. The integrated Bluetooth chip can be a chip with a Bluetooth signal transmission function from CC2540, CC2541, CSR101x, nRF51822 and ESP32. The signal line of the microstrip line antenna needs to have a certain length, and copper cannot be laid around the antenna signal line to maximize the signal.

[0027] Furthermore, the rechargeable lithium battery in the power supply and voltage stabilization module is a secondary lithium battery that can be recharged repeatedly and recycled. The working voltage of the battery cell is 3.6-3.9V, which can provide more powerful power support for the electrocardiogram sensor.

[0028] The voltage regulator chip uses a commonly used integrated circuit, which is mainly used to convert the unstable voltage of the power input into a stable output voltage. The voltage regulator chip can be selected from TPS61040DBVR, MT2492, TPS5430DDAR, TPS54302DDCR and other chips with voltage regulation function output.

[0029] Furthermore, the wireless charging module includes a button battery, and a receiving coil, i.e., a wireless charging coil, is provided inside the button battery. When in the magnetic field of the wireless charging device, the receiving coil will induce current, thereby charging the button battery;

[0030] The button battery is also equipped with a wireless power receiver and a power management chip;

[0031] The first AC port (AC1 port) of the wireless power receiver is connected to the housing, and the second AC port (AC2 port) is connected to the positive electrode ear;

[0032] The input end of the power management chip is connected to the output end of the wireless power receiver, and the output end of the power management chip is connected to the positive electrode of the top cover of the battery;

[0033] When the button battery is in a wireless charging environment, the wireless charging coil outputs alternating current to the two ports of the wireless power receiver, and then the power management chip processes and transmits the electrical energy to the positive and negative poles of the battery;

[0034] The charging chip is an integrated circuit specially used for charging and managing button batteries. You can choose one of CN3130, TP4056 and XB3306A to complete the charging process.

[0035] Furthermore, the ECG sensor is evenly attached to the chest, wrist or ankle of the human body to ensure good contact with the skin, so as to achieve accurate ECG signal detection.

[0036] Before the ECG sensor is attached, the skin of the attachment part needs to be cleaned to remove impurities such as grease and dust that may affect the performance of the sensor. After use, the ECG sensor needs to be cleaned and disinfected to ensure safety and accuracy for the next use. Specific cleaning solutions or disinfection methods can be used.

[0037] A method for using an electrocardiogram sensor prepared based on electronic skin technology, the method comprising: evenly attaching the electrocardiogram sensor to a human body part to collect electrocardiogram signals, amplifying the collected electrocardiogram signals through a preamplifier and transmitting them to a filter, filtering out interference components that do not match the frequency of the required transmitted electrocardiogram signals, and then transmitting the electrocardiogram signals to a digital-to-analog converter, which converts the electrocardiogram signals into digital signals and sends them to a microprocessor, which analyzes and processes the digital signals to obtain corresponding electrocardiogram information, and then transmitting the electrocardiogram information to a mobile device or a computer via a Bluetooth module for diagnosis by a patient or a doctor;

[0038] When the ECG sensor is working, the power supply and voltage stabilization module supplies power to the signal acquisition module and the data processing module.

[0039] In addition, the power supply and voltage regulation module is responsible for the power distribution, monitoring and management of the overall circuit through the power management chip. Although the power management chip can also provide certain power control functions, the charging requirements of button batteries are relatively special and require low-power, small-sized charging chips to meet them. The charging chip can provide constant current and constant voltage charging, overcharge protection, temperature monitoring and other functions based on the chemical characteristics of specific batteries to ensure safe and efficient charging of the battery.

[0040] Compared with the prior art, the present invention has the following advantages:

[0041] The flexible material and light structure design can fit the curve of human skin well, without causing too much pressure on the skin, making it more comfortable to wear and suitable for long-term continuous monitoring. At the same time, due to the use of silver chloride with high conductivity and low noise as the electrode material, it has good electrochemical stability and low contact resistance, and the contact area between the electrode sheet and the human skin is large enough, so that the device has high sensitivity and can accurately capture the slight changes in the heart's electrical signals, providing more accurate data support for the early diagnosis and disease monitoring of heart disease. Low-noise electronic components are used, with less electromagnetic interference and signal coupling, and a preamplifier with a high common-mode rejection ratio is selected to reduce common-mode interference and improve common-mode rejection capability; a stable power supply is used to reduce power supply noise. It has good wearability and can be integrated into various wearable devices, such as smart watches, smart bracelets, smart clothing, etc., so that users can monitor ECG anytime and anywhere, and realize real-time monitoring of heart health. After special material selection and process treatment, it can maintain stable performance during long-term use to ensure continuous and accurate monitoring of ECG signals. BRIEF DESCRIPTION OF THE DRAWINGS

[0042] The drawings described herein are used to provide a further understanding of the present invention, constitute a part of the present application, and do not constitute an improper limitation of the present invention. In the drawings:

[0043] Figure 1 It is a schematic diagram of the composition structure of the electrocardiogram sensor of the present invention;

[0044] Figure 2 It is a working principle diagram of the electrocardiogram monitoring of the present invention. DETAILED DESCRIPTION

[0045] In order to gain a deeper understanding of the present invention, we will provide a comprehensive and detailed description of the present invention. However, the present invention has multiple implementations and is not limited to the specific examples listed herein. The presentation of these examples is intended to deepen the comprehensive understanding of the disclosure of the present invention.

[0046] An electrocardiogram sensor prepared based on electronic skin technology, the electrocardiogram sensor comprising a flexible substrate, a conductive layer, electrocardiogram electrodes, a signal processing circuit, a Bluetooth module and packaging materials; specifically:

[0047] Uniformly coating a conductive material on a flexible substrate to form a conductive layer;

[0048] preparing ECG electrodes at specific positions on the conductive layer;

[0049] The signal processing circuit is integrated via flexible printed circuit board technology or directly on a flexible substrate.

[0050] Furthermore, the material of the flexible substrate is selected to have good flexibility and biocompatibility; the prepolymer of the flexible substrate material and the curing agent are mixed in a certain proportion, stirred evenly, the mixed material is poured into a mold, and cured at a certain temperature to form a flexible substrate;

[0051] The conductive material is selected from metal nanowires;

[0052] The ECG electrode material is usually made of silver chloride or other materials with good conductivity and biocompatibility.

[0053] The packaging material is a material with good biocompatibility, softness and waterproof performance; the entire ECG sensor is packaged with the packaging material (such as silica gel) to protect the internal structure, while improving the biocompatibility and waterproof performance, ensuring that the packaged ECG sensor has good flexibility and durability.

[0054] Furthermore, the material of the flexible substrate is selected to have good flexibility and biocompatibility; the prepolymer of the flexible substrate material and the curing agent are mixed in a certain proportion, stirred evenly, the mixed material is poured into a mold, and cured at a certain temperature to form a flexible substrate;

[0055] The conductive material is selected from metal nanowires;

[0056] The ECG electrode material is usually made of silver chloride or other materials with good conductivity and biocompatibility.

[0057] The packaging material is a material with good biocompatibility, softness and waterproof performance; the entire ECG sensor is packaged with the packaging material (such as silica gel) to protect the internal structure, while improving the biocompatibility and waterproof performance, and ensuring the flexibility and durability of the packaged ECG sensor.

[0058] Furthermore, the signal processing circuit includes a signal acquisition module, a data processing module, a power supply and voltage stabilization module, and a data display module; the signal acquisition, data processing, power supply and voltage stabilization modules constitute the main circuit, control and acquire heart signals, perform secondary processing on the acquired signals, and send the data to a mobile device or computer through a Bluetooth module; wherein:

[0059] The signal acquisition module is composed of a preamplifier, a filter and a digital-to-analog converter. The preamplifier amplifies the weak ECG signal to increase the amplitude of the signal for subsequent processing. At the same time, the preamplifier has the characteristics of high input impedance, low noise, high common mode rejection ratio, etc., which can reduce signal distortion and interference. The preamplifier can be selected from AD620, INA128, etc.

[0060] The data processing module is composed of a microprocessor;

[0061] The power supply and voltage stabilization module is composed of a wireless charging module, a rechargeable lithium battery, a voltage stabilization chip and a charging chip;

[0062] The data display module is composed of a mobile device or a computer.

[0063] Furthermore, the filter is an active bandpass filter for removing noise and interference in the ECG signal. The filter removes noise and interference in the ECG signal to improve the quality of the signal. The filter adopts an active bandpass filter, which can be selected from UAF42, TZJH / UL8, LM358 and FI-B10T(D)-R2 series.

[0064] Furthermore, the preamplifier amplifies the ECG signal to increase the amplitude of the ECG signal.

[0065] Furthermore, the analog-to-digital converter (ADC) converts the analog ECG signal into a digital signal to facilitate digital signal processing and storage; it can be selected from ADC chips such as ADS1292 and ADS1298 that are specifically used for bioelectric signal acquisition.

[0066] Furthermore, the microprocessor further processes and analyzes the digital ECG signal, such as calculating heart rate, detecting arrhythmia, etc. A microprocessor of the ARM series and a microcontroller of the STM32 series can be selected. At the same time, a microprocessor with low power consumption and moderate speed should be required to work for 24 hours or more, and at the same time, the performance requirements of processing data should be met.

[0067] Furthermore, the Bluetooth module sends the ECG signal data packet processed by the microprocessor to a mobile device or a computer. The Bluetooth module can adopt a variety of solutions, and a Bluetooth communication module can be built from an integrated Bluetooth chip and a microstrip line antenna. The integrated Bluetooth chip can be a chip with a Bluetooth signal transmission function from CC2540, CC2541, CSR101x, nRF51822 and ESP32. The signal line of the microstrip line antenna needs to have a certain length, and copper cannot be laid around the antenna signal line to maximize the signal.

[0068] Furthermore, the rechargeable lithium battery in the power supply and voltage stabilization module adopts a secondary lithium battery that can be repeatedly charged and recycled. The working voltage of the battery cell is 3.6-3.9V, which can provide more powerful power support for the ECG sensor. The working temperature of the battery is -25 to 45°C. With the improvement of the electrolyte and the positive electrode, it is expected to be expanded to -40 to 70°C in the future, which is suitable for various working environments. And it has high specific energy. Under the same weight or volume, the secondary lithium battery can store more electrical energy and has a stronger endurance. At the same time, the battery life can generally reach more than 500 times, or even more than 1,000 times, which greatly extends the service life of the battery and reduces the cost of use. And it has good safety performance, does not contain cadmium, lead, mercury and other elements that pollute the environment, and is environmentally friendly; and there is no "memory effect", and it does not need to be fully discharged and then recharged like nickel-cadmium batteries, which is more convenient to use.

[0069] The voltage regulator chip uses a commonly used integrated circuit, which is mainly used to convert the unstable voltage of the power input into a stable output voltage. The voltage regulator chip can be selected from TPS61040DBVR, MT2492, TPS5430DDAR, TPS54302DDCR and other chips with voltage regulation function output.

[0070] Furthermore, the wireless charging module includes a button battery, and a receiving coil, i.e., a wireless charging coil, is provided inside the button battery. When in the magnetic field of the wireless charging device, the receiving coil will induce current, thereby charging the button battery;

[0071] The button battery is also equipped with a wireless power receiver and a power management chip;

[0072] The first AC port (AC1 port) of the wireless power receiver is connected to the housing, and the second AC port (AC2 port) is connected to the positive electrode ear;

[0073] The input end of the power management chip is connected to the output end of the wireless power receiver, and the output end of the power management chip is connected to the positive electrode of the top cover of the battery;

[0074] When the button battery is in a wireless charging environment, the wireless charging coil outputs alternating current to the two ports of the wireless power receiver, and then the power management chip processes and transmits the electrical energy to the positive and negative poles of the battery;

[0075] The charging chip is an integrated circuit specially used for charging and managing button batteries. You can choose one of CN3130, TP4056 and XB3306A to complete the charging process.

[0076] Furthermore, the ECG sensor is evenly attached to the chest, wrist or ankle of the human body to ensure good contact with the skin, so as to achieve accurate ECG signal detection.

[0077] Before the ECG sensor is attached, the skin of the attachment part needs to be cleaned to remove impurities such as grease and dust that may affect the performance of the sensor. After use, the ECG sensor needs to be cleaned and disinfected to ensure safety and accuracy for the next use. Specific cleaning solutions or disinfection methods can be used.

[0078] A method for using an electrocardiogram sensor prepared based on electronic skin technology, the method comprising: evenly attaching the electrocardiogram sensor to a human body part to collect electrocardiogram signals, amplifying the collected electrocardiogram signals through a preamplifier and transmitting them to a filter, filtering out interference components that do not match the frequency of the required transmitted electrocardiogram signals, and then transmitting the electrocardiogram signals to a digital-to-analog converter, which converts the electrocardiogram signals into digital signals and sends them to a microprocessor, which analyzes and processes the digital signals to obtain corresponding electrocardiogram information, and then transmitting the electrocardiogram information to a mobile device or a computer via a Bluetooth module for diagnosis by a patient or a doctor;

[0079] When the ECG sensor is working, the power supply and voltage stabilization module supplies power to the signal acquisition module and the data processing module.

[0080] In addition, the power supply and voltage regulation module is responsible for the power distribution, monitoring and management of the overall circuit through the power management chip. Although the power management chip can also provide certain power control functions, the charging requirements of button batteries are relatively special and require low-power, small-sized charging chips to meet them. The charging chip can provide constant current and constant voltage charging, overcharge protection, temperature monitoring and other functions based on the chemical characteristics of specific batteries to ensure safe and efficient charging of the battery.

[0081] Example 1

[0082] like Figure 1 As shown, this example provides a schematic diagram of the composition structure of an ECG sensor prepared based on electronic skin technology. The sensor is prepared based on a flexible substrate, a conductive layer, ECG electrodes, a signal processing circuit and packaging.

[0083] In this example, the flexible substrate material may be selected from materials having good flexibility and biocompatibility, such as polydimethylsiloxane (PDMS) and polyurethane (PU).

[0084] Conductive materials can be selected from metal nanowires, such as silver nanowires, or conductive polymers, such as polyaniline, polypyrrole, and the like.

[0085] ECG electrode materials usually use materials such as silver chloride that have good conductivity and biocompatibility.

[0086] The packaging material should be biocompatible, soft and waterproof, such as silicone.

[0087] The prepolymer and curing agent of the flexible substrate material are mixed in a certain proportion and stirred evenly. The mixed material is poured into a mold and cured at a certain temperature to form a flexible substrate. The conductive material (such as silver nanowire solution or conductive polymer solution) is evenly coated on the flexible substrate by a solution method, a spraying method or a printing method. The conductive layer is dried or cured to ensure its conductivity and stability. ECG electrodes are prepared by printing, sputtering or deposition at specific positions on the conductive layer. The electrode material can be silver chloride, etc. The electrode is surface treated to improve its contact performance and conductivity with the skin. The tiny ECG signal processing circuit (such as amplifier, filter, etc.) is integrated through flexible printed circuit board technology or directly on the flexible substrate. The conductive layer and the signal processing circuit are connected to ensure accurate signal transmission. The entire sensor is encapsulated with an encapsulation material (such as silicone) to protect the internal structure and improve biocompatibility and waterproof performance. Ensure that the encapsulated sensor has good flexibility and durability.

[0088] Example 2

[0089] like Figure 2As shown, an ECG monitoring circuit of an ECG sensor prepared based on electronic skin technology provided in this example is composed of signal acquisition, data processing, power supply and voltage regulation, and data display unit. Among them, the signal acquisition module is composed of a preamplifier, an active bandpass filter, a digital-to-analog converter, and a Bluetooth module. Because the ECG signal is a weak bioelectric signal, it has the following characteristics: weak amplitude: usually at the millivolt level, easily affected by noise and interference; low frequency range: mainly concentrated between 0.05Hz and 100Hz; susceptible to interference: easily affected by factors such as human body movement, electromagnetic interference, and poor electrode contact. Therefore, the working mechanism of this circuit is that the preamplifier amplifies the collected ECG signal to increase the amplitude of the signal. After being amplified by the preamplifier, the signal is sent to the filter, and the noise and interference in the ECG signal are removed by the filter to improve the quality of the signal. The signal is then transmitted to the digital-to-analog converter, which converts the analog ECG signal into a digital signal for digital signal processing and storage. The signal is then transmitted to a microprocessor for further processing and analysis, such as calculating heart rate, detecting arrhythmias, etc. The results are then transmitted to a mobile device or computer via a Bluetooth module for diagnosis by the patient and the doctor.

[0090] The present invention adopts low-noise electronic components, such as low-noise amplifiers, low-noise power supplies, etc. during design; reasonably arranges circuit boards to reduce electromagnetic interference and signal coupling; and adopts shielding technology, such as shielded cables, shielding covers, etc., to reduce external interference and play a role in noise suppression.

[0091] Choose a preamplifier with a high common-mode rejection ratio to reduce common-mode interference; use differential input to improve common-mode rejection capability; good grounding and shielding can reduce the conduction of common-mode interference and play a role in common-mode rejection;

[0092] Use a stable power supply, such as a linear regulated power supply or a switching regulated power supply, to reduce power supply noise; filter and decouple the power supply to reduce power supply ripple and noise; reasonably distribute the power supply to avoid power supply interference between different circuits, thereby playing a role in power management.

[0093] The contents not described in detail in the specification of the present invention belong to the prior art known to the professional and technical personnel in the field. Although the illustrative specific embodiments of the present invention are described above to facilitate the understanding of the present invention by the technical personnel in the field, it should be clear that the present invention is not limited to the scope of the specific embodiments. For the ordinary technical personnel in the field, as long as various changes are within the spirit and scope of the present invention defined and determined by the attached claims, these changes are obvious, and all inventions and creations using the concept of the present invention are protected.

Claims

1. An electrocardiogram sensor prepared based on electronic skin technology, characterized in that: The ECG sensor includes a flexible substrate, a conductive layer, ECG electrodes, a signal processing circuit, a Bluetooth module and packaging materials; specifically: Uniformly coating a conductive material on a flexible substrate to form a conductive layer; preparing ECG electrodes at specific positions on the conductive layer; The signal processing circuit is integrated via flexible printed circuit board technology or directly on a flexible substrate.

2. The electrocardiogram sensor based on electronic skin technology according to claim 1, characterized in that: The material of the flexible substrate is selected to have good flexibility and biocompatibility; the prepolymer of the flexible substrate material and the curing agent are mixed in a certain proportion, stirred evenly, poured into a mold, and cured at a certain temperature to form a flexible substrate; The conductive material is selected from metal nanowires; The ECG electrode material is made of a conductive and biocompatible material; The packaging material is selected from a material with good biocompatibility, softness and waterproof performance; The entire ECG sensor is encapsulated with encapsulation materials to protect the internal structure, while improving biocompatibility and waterproof performance, and ensuring the flexibility and durability of the encapsulated ECG sensor.

3. The electrocardiogram sensor based on electronic skin technology according to claim 1, characterized in that: The signal processing circuit includes a signal acquisition module, a data processing module, a power supply and voltage stabilization module, and a data display module; wherein: The signal acquisition module is composed of a preamplifier, a filter and a digital-to-analog converter; The data processing module is composed of a microprocessor; The power supply and voltage stabilization module is composed of a wireless charging module, a rechargeable lithium battery, a voltage stabilization chip and a charging chip; The data display module is composed of a mobile device or a computer.

4. The electrocardiogram sensor prepared based on electronic skin technology according to claim 3 is characterized in that: The filter is an active bandpass filter, which is used to remove noise and interference in the ECG signal; The preamplifier amplifies the ECG signal to increase the amplitude of the ECG signal; The analog-to-digital converter converts the analog ECG signal into a digital signal, which is convenient for digital signal processing and storage; The microprocessor further processes and analyzes the digital ECG signal; The voltage stabilizing chip is used to convert the unstable voltage of the power input into a stable output voltage.

5. The electrocardiogram sensor prepared based on electronic skin technology according to claim 3, characterized in that: The wireless charging module includes a button battery, and a receiving coil, i.e., a wireless charging coil, is provided inside the button battery. When in the magnetic field of the wireless charging device, the receiving coil will induce current, thereby charging the button battery; The button battery is also equipped with a wireless power receiver and a power management chip; The first AC port of the wireless power receiver is connected to the housing, and the second AC port is connected to the positive terminal; The input end of the power management chip is connected to the output end of the wireless power receiver, and the output end of the power management chip is connected to the positive electrode of the top cover of the battery; When the button battery is in a wireless charging environment, the wireless charging coil outputs alternating current to the two ports of the wireless power receiver, and then the power management chip processes and transmits the electrical energy to the positive and negative poles of the battery; The charging chip is an integrated circuit used to manage the charging of button batteries.

6. The electrocardiogram sensor based on electronic skin technology according to claim 1, characterized in that: The Bluetooth module sends the ECG signal data packet processed by the microprocessor to the mobile device or computer.

7. The electrocardiogram sensor based on electronic skin technology according to claim 2, characterized in that: The electrocardiogram electrode material is silver chloride.

8. The electrocardiogram sensor based on electronic skin technology according to claim 1, characterized in that: The ECG sensor is evenly attached to the human body to ensure good contact with the skin, so as to achieve accurate ECG signal detection; Before the ECG sensor is attached, the skin of the attachment part needs to be cleaned; After use, the ECG sensor needs to be cleaned and disinfected to ensure safety and accuracy for the next use. Specific cleaning solutions or disinfection methods can be used.

9. A method for using an electrocardiogram sensor prepared based on electronic skin technology, characterized in that: The method comprises: after the ECG sensor is evenly attached to a part of the human body, the ECG signal is collected, the collected ECG signal is amplified by a preamplifier and then transmitted to a filter, the filter filters out interference components that do not match the frequency of the ECG signal to be transmitted, and then the ECG signal is transmitted to a digital-to-analog converter, the digital-to-analog converter converts the ECG signal into a digital signal and sends it to a microprocessor, the microprocessor analyzes and processes the digital signal to obtain corresponding ECG information, and then the ECG information is transmitted to a mobile device or a computer via a Bluetooth module for diagnosis by a patient or a doctor; When the ECG sensor is working, the power supply and voltage stabilization module supplies power to the signal acquisition module and the data processing module.

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