A nasal breath sampling and analysis device

Abstract

The present invention discloses a nasal breath sampling and analysis device, and relates to the field of biological detection technology. It includes: a shell, an air inlet is arranged on the top of the shell, and an air outlet is arranged on the side; an air inlet pipe, the first end of the air inlet pipe is connected to the air inlet, and the second end is connected to a silent pump; an air outlet pipe, the first end of the air outlet pipe is connected to a silent pump, and the second end is connected to a detector; a nasal breathing head, the nasal breathing head is arranged on the top of the shell and connected to the air inlet, and the air inlet pipe is connected to the outside world through the air inlet and the nasal breathing head; the nasal breathing head is truncated cone-shaped, and a positioning boss is arranged on the top of the nasal breathing head, and a plurality of small holes are evenly distributed on the positioning boss, and an airway is arranged inside the nasal breathing head, and the air inlet pipe is connected to the outside world through the air inlet, the airway and the small holes. The overall design of the nasal breathing head of the present invention is truncated cone-shaped, which can better adapt to the shape of the nasal cavity and improve the wearing comfort. A positioning boss is added to the head to ensure that the nasal breathing head is accurately positioned during use to avoid inaccurate sampling angles and depths.

Description

Technical Field

[0001] The present invention relates to the field of biological detection technology, and in particular to a nasal breath sampling and analysis device. Background Art

[0002] With the continuous development of medical research and technology, the detection of metabolites in human exhaled breath to assist in examining the health status of subjects has become a rapidly developing technical method in basic biomedical research and clinical applications. As a non-invasive detection method, nasal exhalation is not affected by differences in oral conditions such as oral inflammation, food residues, and oral microbial metabolism in the subjects, and is therefore widely used in the early diagnosis and health management of respiratory diseases.

[0003] The patent with publication number CN213606527U discloses an oral and nasal dual-purpose exhalation detection filter device, including a respiratory filter handle and a filter. The top of the respiratory filter handle is provided with a groove connected to the filter, and an inhalation passage, an exhalation passage and an exhaust passage are provided inside; the filter is an exhalation filter or an exhaust filter, which is respectively embedded in the groove and sealed and connected with the exhalation passage or the exhaust passage. Although this patent can realize respiratory filtration of exhalation or exhaust sampling, there is no need to repeatedly replace the oral or nasal exhalation filter device and the matching disposable filter, which is easy to operate and improves detection efficiency.

[0004] However, its exhalation head is olive-shaped, and the olive-shaped design has the problem of unclear sampling depth, which will cause large fluctuations in the sampling results and affect the analysis accuracy. Summary of the invention

[0005] The main purpose of the present invention is to provide a nasal breath sampling and analysis device to solve the above problems.

[0006] To achieve the above object, the present invention provides a nasal breath sampling and analysis device, comprising:

[0007] A shell, wherein the top of the shell is provided with an air inlet, and the side of the shell is provided with an air outlet;

[0008] An air intake pipe, wherein a first end of the air intake pipe is connected to the air intake port, and a second end of the air intake pipe is connected to a silent pump;

[0009] An air outlet pipe, wherein a first end of the air outlet pipe is connected to a silent pump, and a second end of the air outlet pipe is connected to a detector;

[0010] A nasal breathing head, wherein the nasal breathing head is arranged at the top of the shell and connected to the air inlet, and the air inlet pipe is connected to the outside world through the air inlet and the nasal breathing head; the nasal breathing head is truncated cone-shaped, and a positioning boss is arranged on the top of the nasal breathing head, and a plurality of small holes are evenly distributed on the positioning boss, and an airway is arranged inside the nasal breathing head, and the air inlet pipe is connected to the outside world through the air inlet, the airway and the small holes.

[0011] Furthermore, a curved surface is provided on one side of the nasal exhalation head, the airway is inclined toward the curved surface by 20-40 degrees, and the top of the positioning boss is inclined toward the curved surface by 20-40 degrees.

[0012] Furthermore, the nasal breathing head is made of soft rubber material, and filter cotton is arranged in the airway.

[0013] Furthermore, a filter element is provided at the air inlet.

[0014] Furthermore, a pressure sensor is provided in the air inlet pipe or the air outlet pipe.

[0015] Furthermore, a centralized controller and a battery compartment are also provided in the shell, the battery compartment is electrically connected to the centralized controller, the silent pump, the detector and the pressure sensor, and a compartment cover of the battery compartment and a button for controlling the centralized controller are provided on the shell.

[0016] Furthermore, a wireless transmitter is also provided in the shell, and the wireless transmitter is electrically connected to the centralized controller, and the wireless transmitter is used to upload the detection result to the cloud.

[0017] Furthermore, a display screen is provided on the housing, and the display screen is electrically connected to the centralized controller.

[0018] Furthermore, a non-slip pad is provided at the bottom of the shell.

[0019] The overall design of the nose breathing head of the present invention is a truncated cone shape, which conforms to ergonomics, can better adapt to the shape of the nasal cavity, and improves wearing comfort. A positioning boss is added to the head to ensure that the nose breathing head is accurately positioned during use to avoid inaccurate sampling angles and depths. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 The overall schematic diagram of a nasal breath sampling and analysis device of the present invention is shown in FIG. Figure 1 .

[0021] Figure 2 The overall schematic diagram of a nasal breath sampling and analysis device of the present invention is shown in FIG. Figure 2 .

[0022] Figure 3The present invention is a side view of a nasal breath sampling and analysis device.

[0023] Figure 4 This is an exploded view of a nasal breath sampling and analysis device of the present invention.

[0024] Figure 5 This is experimental comparison data of a nasal breath sampling and analysis device of the present invention and a traditional nasal breath head.

[0025] Figure 6 This is experimental comparison data 2 of the nasal breath sampling and analysis device of the present invention and the traditional nasal breath head.

[0026] Among them, 1-shell; 2-inlet pipe; 3-silent pump; 4-outlet pipe; 5-detector; 6-nasal breathing head; 7-centralized controller; 8-battery compartment; 9-button; 10-anti-slip pad; 11-compartment cover; 12-air outlet; 13-small hole; 14-arc surface; 15-upper cover; 16-middle cover; 17-lower cover; 18-display screen; 19-bracket. DETAILED DESCRIPTION

[0027] In order to achieve the above-mentioned purpose and effect, the technical means and structures adopted by the present invention are described in detail with reference to the accompanying drawings for the features and functions of the preferred embodiments of the present invention.

[0028] like Figure 1-Figure 4 As shown, the present invention provides a nasal breath sampling and analysis device, comprising:

[0029] The housing 1 has an air inlet at the top and an air outlet 12 at the side;

[0030] An air intake pipe 2, wherein a first end of the air intake pipe 2 is connected to the air intake port, and a second end of the air intake pipe 2 is connected to a silent pump 3;

[0031] An air outlet pipe 4, the first end of which is connected to a silent pump 3, and the second end of which is connected to a detector 5; the silent pump is used to transport the sampled airflow to the detector and reduce the operating noise of the equipment, thereby improving the user experience.

[0032] The nasal breathing head 6 is arranged on the top of the shell 1 and connected with the air inlet. The air inlet pipe 2 is connected with the outside through the air inlet and the nasal breathing head 6.

[0033] Specifically, the housing 1 includes an upper cover 15, a middle cover 16 and a lower cover 17. The middle cover 16 is detachably connected to the upper cover and the lower cover. A bracket 19 for fixing various components is also provided in the housing.

[0034] During actual use, the user turns on the device and presses the nasal exhalation head 6 against the nostrils, exhales into the nasal exhalation head 6, and the gas enters the air inlet pipe 2 through the nasal exhalation head 6. The gas will be transported to the detector 5 under the action of the silent pump 3. The detector 5 detects the gas in real time and quickly detects biomarkers in the gas, such as nitric oxide NO, volatile organic compounds VOC, etc., to help evaluate the health of the respiratory system. After the detection is completed, the detector 5 discharges the gas into the shell 1, and the gas will leave from the outlet 12 on the side wall of the shell 1.

[0035] In this embodiment, the nose breathing head 6 is in the shape of a truncated cone, and a positioning boss is arranged on the top of the nose breathing head 6. The shape of the positioning boss is adapted to the shape of the nostril, and a plurality of small holes 13 are evenly distributed on the positioning boss. An airway is arranged inside the nose breathing head 6, and the air inlet pipe 2 is connected to the outside through the air inlet, the airway and the small holes 13. The user can put the positioning boss into the nostril and then exhale, thereby reducing the possibility of external gas entering and improving the accuracy of the detection result. At the same time, the positioning boss also limits the sampling depth, avoiding sampling that is too deep or too shallow, thereby ensuring that the nose breathing head 6 does not press against the nasal wall when sampling, and ensuring the representativeness and accuracy of the sampled gas.

[0036] Specifically, a curved surface 14 is provided on one side of the nasal breathing head 6, the airway is inclined 20-40 degrees toward the curved surface 14, and the top of the positioning boss is inclined 20-40 degrees toward the curved surface 14. The design of the curved surface 14 allows the curved surface 14 to fit the user's lip surface during sampling, naturally limiting the position, avoiding the sliding of the nasal breathing head 6 during sampling, ensuring the stability of the device during use, and ensuring that the nasal breathing head 6 is accurately positioned during use, avoiding inaccurate sampling angles and depths, and avoiding the problem of low gas composition caused by incorrect sampling angles in traditional designs; the inclination angles of the airway and the positioning boss make the two face the nasal cavity, directly aligning with the upper respiratory tract in the front of the nasal cavity, ensuring that the sampling airflow can accurately enter from the front of the nasal cavity, avoiding airflow deviation, and making the collected gas mainly come from the upper respiratory tract rather than other parts of the nasal cavity or the oral area, ensuring accurate collection of gas components.

[0037] Preferably, the inclination angles of the airway and the positioning boss are the same, both of which are 30°.

[0038] In this embodiment, the nose breathing head 6 is made of soft rubber material, which is soft and elastic, can adapt to different nasal shapes, ensure sealing, and improve comfort during use. Filter cotton is arranged in the airway to effectively prevent liquid substances such as nasal mucus from entering the device, avoiding contamination and damage to the device.

[0039] In this embodiment, a moisture-filtering and dust-proof filter is provided at the air inlet to intercept particles and impurities in the gas sample and ensure the purity of the sample. The filter can be replaced according to usage.

[0040] In this embodiment, a pressure sensor is provided in the air inlet pipe 2 or the air outlet pipe 4 to detect the pressure change in the air flow, monitor the sampling state in real time, and avoid the vacuum state caused by air path blockage.

[0041] In another embodiment, a centralized controller 7 and a battery compartment 8 are also provided in the shell 1. The battery compartment 8 is electrically connected to the centralized controller 7, the silent pump 3, the detector 5 and the pressure sensor. A compartment cover 11 of the battery compartment 8 and a button 9 for controlling the centralized controller 7 are provided on the shell 1.

[0042] Specifically, a wireless transmitter and a storage module are also provided in the shell 1, and the wireless transmitter and the storage module are electrically connected to the centralized controller 7, so that the detection data is stored through the storage module, and the detection results are uploaded to the cloud through the wireless transmitter, so as to facilitate remote monitoring by users.

[0043] Preferably, a display screen 18 is also provided on the housing 1, and the display screen 18 is electrically connected to the centralized controller 7. The display screen 18 can display test data and operation status, and provide real-time feedback of analysis results.

[0044] Preferably, an anti-slip pad 10 is provided at the bottom of the housing 1 to facilitate placement of the device.

[0045] The present invention also simulates the model through software and performs actual comparative tests.

[0046] Software simulation: Using the fluid analysis module provided by SolidWorks, the nasal breathing head and nasal cavity 3D model were imported, and the temperature and humidity, surface roughness, flow rate and pressure of the air inlet and outlet and other preconditions were set. The software automatically analyzed the patency of the flow channel, whether there was dead space, vortex, blockage, etc. The results showed that under the design of the nasal breathing head of the present invention, the direction of the sampling airflow was just aligned with the middle of the nostril, and the airflow could smoothly enter the sampling channel without being hindered by the nasal cavity wall, thereby ensuring that the collected gas samples were not disturbed.

[0047] Actual comparative test: Each subject used the adult mode to test the two nasal breathing tips three times, recorded each set of test results and calculated the standard deviation, and then performed a significance analysis on the two sets of standard deviation data to compare the consistency. Figure 5-Figure 6 shown.

[0048] Comparison of standard deviation mean: The standard deviation mean of the nasal air tip of the present invention is significantly lower than that of the traditional olive-shaped nasal air tip, indicating that the test results of the nasal air tip of this embodiment fluctuate less.

[0049] Significance analysis: Through the independent sample t-test, the significance analysis result P<0.05, indicating that the consistency of the nasal nozzle of the present invention is significantly better than that of the traditional olive-shaped nasal nozzle.

[0050] Actual tests show that the airflow is smooth during the sampling process using the nasal breathing tip of the present invention, the collected gas samples are stable, and the sampling depth is maintained in the front part of the nasal cavity, which meets the design requirements. By comparison with the traditional nasal breathing tip, the nasal breathing tip of the present invention performs well in consistency and accuracy, with a significantly lower standard deviation and more reliable test results.

[0051] The above are only preferred embodiments of the present invention, not all embodiments. Anyone should be aware that any structural changes made under the inspiration of the present invention, and any technical solutions that are the same or similar to the present invention, belong to the protection scope of the present invention.

Claims

1. A nasal breath sampling and analysis device, characterized in that: include: A housing (1), wherein the top of the housing (1) is provided with an air inlet, and the side of the housing (1) is provided with an air outlet (12); An air intake pipe (2), wherein a first end of the air intake pipe (2) is connected to the air intake port, and a second end of the air intake pipe (2) is connected to a silent pump (3); An air outlet pipe (4), wherein a first end of the air outlet pipe (4) is connected to the silent pump (3), and a second end of the air outlet pipe (4) is connected to a detector (5); A nasal breathing head (6), wherein the nasal breathing head (6) is arranged on the top of the shell (1) and connected to the air inlet, and the air inlet pipe (2) is connected to the outside through the air inlet and the nasal breathing head (6); the nasal breathing head (6) is truncated cone-shaped, and a positioning boss is arranged on the top of the nasal breathing head (6), and a plurality of small holes (13) are evenly distributed on the positioning boss; an airway is arranged inside the nasal breathing head (6), and the air inlet pipe (2) is connected to the outside through the air inlet, the airway and the small holes (13).

2. A nasal breath sampling and analysis device as claimed in claim 1, characterized in that: A curved surface (14) is provided on one side of the nasal exhalation head (6), the airway is inclined 20-40 degrees toward the curved surface (14), and the top of the positioning boss is inclined 20-40 degrees toward the curved surface (14).

3. A nasal breath sampling and analysis device as claimed in claim 1, characterized in that: The nasal breathing head (6) is made of soft rubber material, and filter cotton is arranged in the airway.

4. A nasal breath sampling and analysis device as claimed in claim 1, characterized in that: A filter element is arranged at the air inlet.

5. A nasal breath sampling and analysis device as claimed in claim 1, characterized in that: A pressure sensor is arranged in the air inlet pipe (2) or the air outlet pipe (4).

6. A nasal breath sampling and analysis device as claimed in claim 5, characterized in that: A centralized controller (7) and a battery compartment (8) are also provided in the housing (1); the battery compartment (8) is electrically connected to the centralized controller (7), the silent pump (3), the detector (5) and the pressure sensor; a compartment cover (11) of the battery compartment (8) and a button (9) for controlling the centralized controller (7) are provided on the housing (1).

7. A nasal breath sampling and analysis device as claimed in claim 6, characterized in that: A wireless transmitter is also provided in the housing (1), the wireless transmitter is electrically connected to the centralized controller (7), and the wireless transmitter is used to upload the detection results to the cloud.

8. A nasal breath sampling and analysis device as claimed in claim 7, characterized in that: The housing (1) is also provided with a display screen (18), and the display screen (18) is electrically connected to the centralized controller (7).

9. A nasal breath sampling and analysis device as claimed in claim 1, characterized in that: An anti-slip pad (10) is provided at the bottom of the housing (1).

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