Plasma treatment apparatus and control method thereof

Abstract

The invention relates to the technical field of medical instruments, and provides a plasma treatment device and a control method thereof.The plasma treatment device comprises a flexible plasma patch, a power module and a control module; the flexible plasma patch comprises a first dielectric barrier layer, an electrode layer, a second dielectric barrier layer and a medical film layer which are sequentially stacked from top to bottom, the medical film layer is suitable for being in contact with a wound surface, the electrode layer comprises a positive electrode, a negative electrode and an auxiliary electrode, the positive electrode and the negative electrode are arranged on the substrate in a coplanar mode, and the auxiliary electrode is connected with the negative electrode; electric field distribution can be changed; the power module is electrically connected with the positive electrode and the negative electrode; the control module is connected with the power module and used for controlling the power module to work. Spatial distribution of an electric field can be better controlled, fine management of a plasma generation area is achieved, hot spots or dead zones are avoided, uniform energy deposition is ensured, and the safety of the flexible plasma patch is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a plasma treatment device and a control method thereof. Background Art

[0002] Plasma therapy device is an innovative medical device that combines modern technology with traditional therapies. It is used in many fields such as wound healing, skin disease treatment, and pain relief. The core of plasma therapy device is to generate active particles with biological effects through controllable plasma technology, thereby promoting tissue repair and regeneration. Plasma is a special state of matter that contains components such as high-energy electrons, ions, and neutral particles. Among them, low-temperature plasma has significant advantages in sterilization, promoting healing, promoting coagulation, and killing tumor cells due to its low temperature and active biochemical properties.

[0003] Although the plasma therapy device in the related art can achieve functions such as wound healing and skin disease treatment through flexible plasma patches, flexible plasma patches are prone to produce hot spots or dead zones during operation. When hot spots are generated, excessive heat concentration causes the local temperature to rise sharply, which can easily cause protein denaturation and cell membrane damage, delaying or even hindering wound healing; "dead zones" mean places where the treatment method cannot reach or the force is insufficient, and the plasma cannot be evenly distributed, weakening the sterilization and disinfection effect. Summary of the invention

[0004] The present invention provides a plasma treatment device and a control method thereof, which are used to solve the above-mentioned technical defects in the prior art, can better control the spatial distribution of the electric field, realize the refined management of the plasma generation area, avoid hot spots or dead zones, ensure uniform energy deposition, and improve the safety of the flexible plasma patch.

[0005] A first aspect of the present invention provides a plasma treatment device, comprising a flexible plasma patch, a power module and a control module, wherein the flexible plasma patch comprises a first dielectric barrier layer, an electrode layer, a second dielectric barrier layer and a medical film layer stacked in sequence from top to bottom, wherein the medical film layer is suitable for contacting a wound surface, wherein the electrode layer comprises a positive electrode, a negative electrode and an auxiliary electrode, wherein the positive electrode and the negative electrode are coplanarly arranged on a substrate, and the auxiliary electrode is connected to the negative electrode for changing an electric field distribution; the power module is electrically connected to the positive electrode and the negative electrode; and the control module is connected to the power module for controlling the operation of the power module.

[0006] The plasma treatment device provided according to the present invention further includes a power regulation module, which is electrically connected to the power module and the control module respectively, and is used to receive control instructions from the control module and control the output power of the power module.

[0007] According to the plasma treatment device provided by the present invention, the flexible plasma patch further comprises a switching component, which is integrally connected to the electrode wires of the positive electrode and the negative electrode and is electrically connected to the power module.

[0008] According to the plasma treatment device provided by the present invention, the flexible plasma patch further comprises a heating element, the heating element is located between the second dielectric barrier layer and the medical film layer, and the heating element is electrically connected to the power module.

[0009] According to the plasma treatment device provided by the present invention, the flexible plasma patch also includes a monitoring module, which is arranged between the second dielectric barrier layer and the medical film layer and is used to monitor the temperature and humidity of the wound surface. The monitoring module is electrically connected to the control module.

[0010] According to the plasma treatment device provided by the present invention, first through holes are provided at intervals on the first dielectric barrier layer, and the first through holes are provided corresponding to the gaps between the electrode layers; The second dielectric barrier layer is provided with second through holes at intervals, and the positions of the second through holes correspond to the positions of the first through holes; The medical film layer is provided with a third through hole, and the position of the third through hole corresponds to the position of the second through hole.

[0011] According to the plasma treatment device provided by the present invention, along the thickness direction of the flexible plasma patch, the apertures of the first through hole, the second through hole and the third through hole gradually increase from top to bottom.

[0012] According to the plasma treatment device provided by the present invention, the aperture of the first through hole is smaller than the aperture of the second through hole, and the aperture of the second through hole is smaller than the aperture of the third through hole.

[0013] A second aspect of the present invention provides a control method based on the plasma treatment device, comprising the following steps: When it is determined that the wound surface meets the treatment conditions, the power supply module is controlled to turn on to supply power to the positive electrode and the negative electrode, so as to form plasma between the positive electrode and the negative electrode to treat the wound surface; Determine that the operation time of the power module meets the preset operation time, and control the power module to shut down.

[0014] The control method of the plasma treatment device provided by the present invention further includes the following steps: Obtain temperature and humidity information of the wound surface; When it is determined that the humidity information of the wound surface is greater than the preset humidity information and the temperature information is less than the preset temperature information, the heating element is controlled to operate; until the humidity information of the wound surface meets the preset humidity information, the heating element is controlled to stop operating; When it is determined that the humidity information of the wound surface is greater than the preset humidity information, and the temperature information is greater than or equal to the preset temperature information, the heating element is controlled to stop running, and the wound surface is quickly dried by the natural airflow through the through hole.

[0015] The plasma treatment device provided by the present invention comprises a flexible plasma patch, a power module and a control module. The flexible plasma patch is provided with a medical film layer below a structure composed of a first dielectric barrier layer, an electrode layer and a second dielectric barrier layer stacked sequentially from top to bottom, so that the medical film layer is used as a substrate for plasma generation. The film layer needs to be compatible with the plasma generation mechanism to ensure that the plasma can penetrate into the treatment site under safe conditions to play the functions of sterilization, healing promotion and analgesia. At the same time, the electrode layer includes a positive electrode, a negative electrode and an auxiliary electrode. The positive electrode and the negative electrode are both suitable for connecting to the power module for discharge. The auxiliary electrode is connected to the negative electrode to change the electric field distribution, guide the formation path and diffusion range of the plasma, and can better control the spatial distribution of the electric field, realize the refined management of the plasma generation area, avoid hot spots or dead zones, ensure uniform energy deposition, and improve the safety of the flexible plasma patch.

[0016] The control method of the plasma treatment device provided by the present invention can achieve the effects of sterilizing the wound surface, promoting healing, etc. by generating low-temperature plasma, and has a better treatment effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the technical solutions in the present invention or the prior art, a brief introduction will be given below to the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0018] Figure 1 It is a schematic diagram of the structure of a flexible plasma patch provided by an embodiment of the present invention.

[0019] Figure 2 It is a schematic diagram of the structural decomposition of the flexible plasma patch provided by an embodiment of the present invention.

[0020] Figure 3 is an axonometric cross-sectional view of a flexible plasma patch provided by an embodiment of the invention.

[0021] Figure 4 yes Figure 3 A partial schematic diagram of a flexible plasma patch provided by an embodiment of the invention is shown.

[0022] Figure 5 It is a schematic diagram of the partial structural decomposition of the flexible plasma patch provided in the embodiment of the invention.

[0023] Figure 6 It is a schematic diagram of the structure of the electrode layer in the flexible plasma patch provided in an embodiment of the invention.

[0024] Figure 7 is a top view of a flexible plasma patch provided by an embodiment of the invention.

[0025] Figure 8 It is a control block diagram of a plasma treatment device provided by an embodiment of the present invention.

[0026] Fig. 9 It is a flow chart of a control method of a plasma treatment device provided by an embodiment of the present invention.

[0027] Reference numerals: 10. First dielectric barrier layer; 11. First through hole; 20. Electrode layer; 21. Positive electrode; 22. Negative electrode; 23. Auxiliary electrode; 30. Second dielectric barrier layer; 31. Second through hole; 40. Medical film layer; 41. Third through hole; 50. Adapter component; 60. Control module; 70. Power module; 80. Monitoring module; 90. Power regulation module; 100. Heating element. DETAILED DESCRIPTION

[0028] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the drawings of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0029] In the description of the embodiments of the present application, it should be noted that, unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in the embodiments of the present application can be understood according to specific circumstances.

[0030] In the embodiments of the present application, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0031] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the embodiments of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0032] See also Figures 1 to 8 An embodiment of the present invention provides a plasma treatment device, which includes a flexible plasma patch, a control module 60 and a power module 70.

[0033] The flexible plasma patch includes a first dielectric barrier layer 10, an electrode layer 20, a second dielectric barrier layer 30 and a medical film layer 40 which are stacked in sequence from top to bottom. The medical film layer 40 is suitable for contacting the wound surface. The electrode layer 20 includes a positive electrode 21, a negative electrode 22 and an auxiliary electrode 23. The positive electrode 21 and the negative electrode 22 are coplanarly arranged on a substrate. The auxiliary electrode 23 is connected to the negative electrode 22 to change the electric field distribution.

[0034] Among them, the medical film layer 40 is suitable for contacting the wound surface, which includes but is not limited to polyurethane, polyethylene, and polyvinyl chloride. At the same time, an adhesive layer can be set on the medical film layer 40 to fix the flexible plasma patch as a whole near the patient's wound surface, that is, to fix the flexible plasma patch to the target area, to ensure that the plasma release is stable and uniform, and it will not fall off easily, and it can maintain good adhesion even in exercise or sleep, reducing secondary damage caused by tearing again. The medical film layer 40 can also be used as a substrate for plasma generation. The film layer needs to be compatible with the plasma generation mechanism to ensure that the plasma can penetrate into the treatment site under safe conditions to play the functions of sterilization, healing, and analgesia.

[0035] The first dielectric barrier layer 10 and the second dielectric barrier layer 30 are used as flexible substrates to provide support and a flat working interface, suitable for close contact with the skin or other treatment parts. The first dielectric barrier layer 10 and the second dielectric barrier layer 30 are both made of the same insulating dielectric material, including but not limited to silicone rubber, silica gel, gel, polyimide, and polydimethylsiloxane. The first dielectric barrier layer 10 and the second dielectric barrier layer 30 can also be made of polymer films, such as PET (polyethylene terephthalate), PU (polyurethane), PVC (polyvinyl chloride), etc., to ensure that the patch has flexibility and comfort.

[0036] The power module 70 is electrically connected to the positive electrode 21 and the negative electrode 22 respectively, and is used to provide necessary high frequency or pulse voltage to the electrodes to generate the electric field required for plasma discharge.

[0037] The control module 60 is connected to the power module 70 and is used to control the operation of the power module 70. The control module 60 includes a microcontroller, a signal processor, a display, etc., and is responsible for monitoring and adjusting various parameters to ensure the safety and effectiveness of treatment.

[0038] It can be understood that the plasma treatment device provided by the embodiment of the present invention includes a flexible plasma patch, a power module and a control module. The flexible plasma patch is provided with a medical film layer 40 below a structure consisting of a first dielectric barrier layer 10, an electrode layer 20 and a second dielectric barrier layer 30 stacked in sequence from top to bottom. At the same time, the electrode layer 20 includes a positive electrode 21, a negative electrode 22 and an auxiliary electrode 23. The positive electrode 21 is provided on one side of the first dielectric barrier layer 10, the negative electrode 22 is provided on one side of the second dielectric barrier layer 30, and the auxiliary electrode 23 is connected to the negative electrode to change the electric field distribution, guide the formation path and diffusion range of the plasma, and better control the spatial distribution of the electric field, realize the refined management of the plasma generation area, avoid hot spots or dead zones, ensure uniform energy deposition, and improve the safety of the flexible plasma patch.

[0039] By adding auxiliary electrodes, the flexible plasma patch can generate a plasma field through three-electrode plasma. Compared with the plasma field generated by two-electrode plasma, it can better control the spatial distribution of the electric field, realize the refined management of the plasma generation area, avoid hot spots or dead zones, and ensure uniform energy deposition; the composite electric field formed by the participation of the auxiliary electrode is conducive to improving the electron density and mean free path, thereby increasing the efficiency of the excitation and ionization process and generating more active species (ROS, RNS, etc.); the three-electrode architecture helps to stabilize the plasma discharge mode, reduce the risk of spark discharge, extend the equipment operation cycle, and improve overall safety; the three-electrode system can often achieve lower power consumption, which is more economical for large-scale production or continuous operation.

[0040] In some embodiments of the invention, the plasma treatment device further includes a power regulation module 90, which is electrically connected to the power module 70 and the control module 60, respectively. The power regulation module 90 is used to receive control instructions from the control module 60 and control the power output of the power module 70.

[0041] In some embodiments of the invention, the flexible plasma patch further includes a transition component 50, the transition component 50 is integrally connected to the electrode wires of the electrode layer 20, and the transition component 50 is suitable for connecting to a power module.

[0042] The flexible plasma patch is conveniently connected to the power module by providing the adapter component 50. The adapter component 50 can be provided with a standardized plug and socket, allowing the flexible plasma patch to be quickly connected to the power module, which is convenient for maintenance and connection.

[0043] In some embodiments of the present invention, a heating element 100 may be integrated on the flexible plasma patch, and the heating element 100 is electrically connected to the power module 70 .

[0044] The heating element 100 can be a resistive heating wire, a graphene heating sheet or a conductive polymer heating film. When current passes through the resistance wire, electrical energy is converted into thermal energy, causing the resistance wire to heat up, and then transferring the heat to the surrounding plasma. When current passes through the graphene heating sheet, the electrons in the graphene lattice are accelerated under the action of the electric field, collide with the lattice atoms, and convert electrical energy into thermal energy. When a voltage is applied to the conductive polymer heating film, the carriers inside the conductive polymer move in a directional manner under the action of the electric field, collide with the polymer molecular chain, and generate heat.

[0045] Although the flexible plasma patch mainly excites gas molecules to generate plasma through the electric field between electrodes, adding an appropriate heating mechanism can optimize the plasma generation conditions and improve its therapeutic effect.

[0046] In some embodiments of the present invention, the flexible plasma patch further includes a monitoring module, which is disposed between the second dielectric barrier layer 30 and the medical film layer 40 and is used to monitor the temperature and humidity of the wound surface. The monitoring module is electrically connected to the control module 60 .

[0047] The monitoring module 80 may be a structure such as a temperature and humidity sensor, which is used to monitor the temperature and humidity information of the wound surface, and feed back the collected temperature and humidity information to the control module 60, and the control module 60 controls the operation of the heating element 100.

[0048] In some embodiments of the invention, first through holes 11 are provided at intervals on the first dielectric barrier layer 10, and the first through holes 11 are provided corresponding to the gaps of the electrode layer 20, and gaps are provided between the electrodes on the electrode layer 20; second through holes 31 are provided at intervals on the second dielectric barrier layer 30, and the positions of the second through holes 31 correspond to the positions of the first through holes 11, which is equivalent to the flexible plasma patch being provided with through holes consisting of the first through holes 11, the gaps and the second through holes 31. The medical film layer 40 is provided with a third through hole 41, and the position of the third through hole 41 corresponds to the position of the second through hole 31. It is equivalent to providing through holes throughout the flexible plasma patch composed of the first dielectric barrier layer 10, the electrode layer 20, the second dielectric barrier layer 30 and the medical film layer 40 stacked in sequence from top to bottom, so as to improve the treatment efficiency and promote wound healing.

[0049] It can be understood that the flexible plasma patch composed of the first dielectric barrier layer 10, the electrode layer 20, the second dielectric barrier layer 30 and the medical film layer 40 stacked in sequence from top to bottom is provided with through holes. On the one hand, the outside air can enter the wound through the through holes to increase the generation of active particles and effectively improve the treatment efficiency; on the other hand, the ozone generated by the discharge of the electrode layer 20 can flow out from the through holes, thereby reducing ozone accumulation, avoiding tissue oxidative stress caused by ozone accumulation, leading to cell membrane lipid peroxidation, and promoting the wound healing process.

[0050] Due to the accumulation of ozone volume generated during wound treatment, high concentrations of ozone are toxic to living cells. Long-term concentration in a certain part can easily cause tissue oxidative stress, leading to cell membrane lipid peroxidation, and then triggering an inflammatory response, delaying the wound healing process. In addition, a large amount of ozone will inhibit the function of white blood cells, interfere with normal immune responses, weaken the body's ability to resist infection, and is not conducive to the defense and repair of the wound. The flexible plasma patch provided in the embodiment of the invention provides an escape channel for ozone by setting the first through hole 11 and the second through hole 31 in positions corresponding to each other, which can reduce the accumulation of ozone at the location of the wound, thereby promoting the wound healing process and improving the treatment efficiency.

[0051] In some embodiments of the invention, along the thickness direction of the flexible plasma patch, the apertures of the first through hole 11, the second through hole 31 and the third through hole 41 gradually increase from top to bottom, that is, along the thickness direction of the flexible plasma patch, the apertures of the first through hole 11, the second through hole 31 and the third through hole 41 gradually decrease from bottom to top.

[0052] Equivalently, the first through hole 11, the second through hole 31 and the third through hole 41 can all be conical holes or trapezoidal holes, and the aperture of the first through hole 11 gradually increases, the top size of the second through hole 31 is the same as the bottom size of the first through hole 11, the aperture of the second through hole 31 gradually increases, the top size of the third through hole 41 is the same as the bottom size of the second through hole 31, and the aperture of the third through hole 41 gradually increases.

[0053] That is, the bottom aperture of the third through hole 41 is the largest, and the top aperture of the first through hole 11 is the smallest. This arrangement is equivalent to the through hole close to the wound surface having a larger aperture, and the through hole away from the wound surface having a smaller aperture, thereby preventing water vapor or other liquids from entering the flexible plasma patch through the through hole.

[0054] It should be noted that the entire through-hole setting of the flexible plasma patch can precisely control the diameter and arrangement of the through-holes according to the specific wound conditions, and utilize the principle of capillary phenomenon to make the pore size small enough to allow liquid droplets to enter, but allow air and ozone to pass freely.

[0055] In addition, a hydrophobic layer may be coated around each third through hole 41 on the medical film layer 40 or on the entire film surface, so that the medical film layer 40 is not easily wetted even when encountering water vapor, thereby preventing moisture from penetrating the flexible plasma patch. Alternatively, a hygroscopic material layer is provided at the lower layer of the medical film layer 40 at the position of the third through hole 41, and the hygroscopic material layer quickly absorbs moisture near the electrode layer 20, so that even if a small amount of liquid accidentally penetrates, it will be absorbed by the hygroscopic material layer in time, thereby protecting the circuit of the electrode layer 20 from damage.

[0056] In some embodiments of the invention, the aperture of the first through hole 11 is smaller than the aperture of the second through hole 31 , and the aperture of the second through hole 31 is smaller than the aperture of the third through hole 41 .

[0057] In other words, the first through hole 11, the second through hole 31 and the third through hole 41 are all cylindrical straight holes, and the through hole formed by the first through hole 11, the second through hole 31 and the third through hole 41 and penetrating the flexible plasma patch is a step hole, which can accelerate the air flow in the vertical direction and help to replenish the working gas. At the same time, the step hole increases the surface area of ​​air interaction, promotes the smooth flow of airflow, and can effectively improve the treatment efficiency.

[0058] In some embodiments of the invention, at least two first through holes 11 form a first hole group; on the same projection plane, the layout area of ​​each first hole group covers the opening area of ​​the second through hole 31; the aperture of the third through hole 41 is greater than or equal to the aperture of the second through hole 31.

[0059] Since the first through hole 11 is connected to the outside air, the aperture of the first through hole 11 determines whether external pollution can enter the wound surface and the wound. Therefore, by opening the position of the original first through hole 11 into at least two first through holes 11 of different shapes, by reducing the size of a single first through hole 11 and increasing the number of first through holes 11 in the same area, the size of the first through hole 11 can be effectively reduced, thereby further isolating external pollution and preventing microorganisms, dust and other harmful substances from invading the wound surface and the wound.

[0060] In this embodiment, the aperture of the third through hole 41 is greater than or equal to the aperture of the second through hole 31, and the aperture of the first through hole 11 must be smaller than the aperture of the second through hole 31, so that the through hole penetrating the flexible plasma patch composed of the first through hole 11, the second through hole 31 and the third through hole 41 is also large in size close to the wound surface, and small in size at one end away from the wound surface and connected to the outside air, thereby preventing external pollution from entering the interior of the flexible plasma patch from the first through hole 11.

[0061] In some embodiments of the invention, at least three first through holes 11 form a first hole group, at least two second through holes 31 form a second hole group, the layout area of ​​each first hole group corresponds to the layout area of ​​each second hole group, and the number of through holes in each first hole group is greater than the number of through holes in the corresponding second hole group; on the same projection plane, the layout area of ​​each second hole group covers the opening area of ​​the third through hole 41.

[0062] Equivalently, in this embodiment, by opening at least three first through holes 11 of different shapes at the original position of one first through hole 11, the size of a single first through hole 11 is reduced, and the number of first through holes 11 in the same area is increased; at the same time, by opening at least two second through holes 31 of different shapes at the original position of one second through hole 31, the size of a single second through hole 31 is reduced, and the number of second through holes 31 in the same area is increased. And the size of the third through hole 41 is always kept larger than the size of the second through hole 31, and the size of the second through hole 31 is larger than the size of the first through hole 11, the capillary phenomenon principle can be effectively utilized, so that the aperture is small enough to allow liquid droplets to enter, but can allow air and ozone to pass freely, ensuring that the flexible plasma patch has a good therapeutic effect while effectively preventing pollutants from entering from each through hole in turn and contacting the wound surface.

[0063] In some embodiments of the invention, an ozone catalyst may be further provided on the hole wall of each third through hole 41 or the hole wall of the second through hole 31 to quickly decompose excess ozone into oxygen. The hydroxyl radicals (·OH) formed by ozone under the action of the ozone catalyst have a higher reaction rate with organic matter and a stronger oxidizing property, thereby oxidizing and decomposing macromolecular organic matter into small molecules, making them easier to be degraded, thereby improving the treatment efficiency.

[0064] When the medical film layer 40 is not provided on the flexible plasma patch, an ozone catalyst is provided on the hole wall of the second through hole 31. When the medical film layer 40 is provided on the flexible plasma patch, an ozone catalyst is provided on the hole wall of the third through hole 41 to quickly decompose excess ozone.

[0065] It should be noted that the shapes of the first through hole 11 , the second through hole 31 and the third through hole 41 include but are not limited to circle, oval, square, bar, polygon, special shape, etc., special shape such as pentagon or heart shape.

[0066] It should also be noted that the flexible plasma patch provided in the embodiment of the invention can use computer simulation software to predict the distribution pattern of each through hole at different apertures and spacings according to the wound area, depth, shape, etc. of the wound surface to adapt to different wound surface conditions.

[0067] In some embodiments of the present invention, the shape of the discharge electrode is not limited to comb, grid, spiral and honeycomb.

[0068] When a high voltage AC or DC voltage is applied between the comb-shaped electrode (positive electrode) and the ground (or negative electrode), a strong electric field will be formed between the electrodes. When the electric field strength exceeds the breakdown electric field of the gas molecules, the molecules in the air on the wound surface will be strongly ionized and decomposed into charged particles (electrons, positive ions and free radicals). The charged particles move faster under the action of the electric field, collide with other neutral molecules, and further produce more charged particles, forming an avalanche-like chain reaction. As the electron density increases, the local current increases sharply, forming a discharge channel. The high temperature and high-energy electrons in the discharge channel cause the gas molecules to be completely ionized, forming a plasma composed of ions, electrons and excited molecules. The plasma propagates outward from the discharge area through electrodynamics and thermal diffusion, effectively sterilizing the wound surface and achieving the purpose of treatment.

[0069] Among them, the edge or tip of the comb-tooth electrode has a small radius of curvature, and the electric field strength is greatly enhanced, which can lead to electric field concentration. In other words, the sharp tip of the comb-tooth electrode can locally amplify the electric field, reducing the voltage required for discharge, so that plasma discharge can be achieved at a lower energy input, thereby reducing thermal damage to surrounding tissues. In addition, the multi-tooth arrangement can form a dense discharge lattice, achieving uniform coverage over a larger area, which is suitable for scenarios such as large-area wound treatment or surface processing.

[0070] When the power module provides high voltage electricity between the spiral positive electrode and the negative electrode, an electromagnetic field in the spiral direction is generated. Under the combined action of the strong magnetic field and electric field, the gas molecules are ionized, and the electrons are stripped from the atoms to form electrons and ions. The structure of the spiral electrode guides the electrons and ions to move along the spiral path. The charge accumulation on the spiral path triggers discharge. During the discharge process, the gas molecules are transformed into a plasma state due to ionization and heating, forming a stable plasma cloud. The plasma cloud is affected by the spiral magnetic field and propels along the spiral axis, showing a spiral or vortex motion.

[0071] Since the plasma cloud generated by the spiral electrode discharge can be output in a specific direction, a magnetic component can be added to the treatment end 12. The magnetic component can generate a magnetic field, and the output direction of the plasma can be further regulated by adding an additional magnetic field, thereby providing targeted treatment for the wound that needs treatment.

[0072] The grid electrode is usually composed of a series of interwoven metal wires or strips, which alternately serve as positive and negative electrodes to form multiple intersections and gaps. When the external power module applies potential to the positive and negative electrodes respectively, a strong electric field is established in the gaps of the grid. Under the action of the electric field, the electrons in the gas molecules are pulled and begin to separate from the atoms or molecules to form free electrons. The free electrons are accelerated by the electric field and collide with more gas molecules to form new electron-ion pairs. As the electron density continues to increase, the local electric field becomes extremely strong, enough to completely break down the gas medium to form a discharge. The discharge path spreads along the gaps of the grid, forming many dispersed but connected small discharge channels, which increases the effective area covered by the plasma. In the discharge channel, a large number of electrons, positive ions and excited molecules gather to form a dense plasma cloud. The generated plasma diffuses from the discharge channel to achieve the sterilization and disinfection function of the plasma.

[0073] The honeycomb-shaped electrode generally contains a set of central electrodes (usually positive electrodes) and annular or hexagonal negative electrodes surrounding it. The gap in the middle is filled with gas medium. When a high-voltage power supply applies voltage between the central electrode and the peripheral electrodes, a non-uniform electric field is formed between the two. Due to the unique arrangement of the electrodes, the electric field is very concentrated inside each unit of the honeycomb, especially near the central electrode, forming a highly concentrated electric field gradient. The central electrode attracts free electrons and other charged particles in the surrounding space to move toward it. At the same time, the negative electrode repels these charged particles, causing charges to accumulate around the central electrode. When the electric field strength is large enough, it causes the gas medium to be ionized and form charge carriers (electrons and positive ions). The medium after breakdown forms a discharge channel. The high-energy particles in the discharge channel continue to interact with other molecules to form a large number of ions, electrons and active species, namely plasma. The plasma is not only confined to the discharge channel, but will diffuse into the wound surface to sterilize and disinfect the wound surface.

[0074] Among the above-mentioned electrodes, the fine tooth edges of the comb-tooth electrode can focus the electric field, which is suitable for the treatment of local lesions, with less damage to normal tissues around the wound, and suitable for the treatment of deep skin infections. It can effectively kill bacteria without damaging healthy tissues. Since the honeycomb electrode can provide a more uniform discharge distribution and the plasma coverage area is wide, it is suitable for the treatment of larger wounds. Since the grid electrode has strong permeability, it is suitable for treatment deep inside the tissue or in complex morphological parts, which is beneficial for the treatment that needs to penetrate into the deep tissue and can achieve deep purification and repair. Since the spiral electrode uses the spiral discharge characteristics and directional plasma flow, it can form a directional treatment effect in deep tissues. The ability to deliver plasma in a directional manner enhances the accuracy and safety of treatment and is suitable for targeted treatment.

[0075] An embodiment of the present invention further provides a control method for a plasma treatment device, and the control method for a plasma treatment device includes the following steps S100 and S200.

[0076] Step S100: When it is determined that the wound surface meets the treatment conditions, the power supply module 70 is controlled to supply power to the positive electrode 21 and the negative electrode 22 to form plasma between the positive electrode 21 and the negative electrode 22 for wound treatment.

[0077] It is understandable that before determining that the wound meets the treatment conditions, a multi-dimensional wound assessment is required. In addition to the conventional wound size and depth measurements, the infection of the wound needs to be accurately detected. If infection is found, appropriate anti-infection pretreatment is required, such as local application of antibiotic ointment or debridement, to ensure the effectiveness and safety of subsequent plasma treatment. After confirming that the wound meets the treatment conditions, perform meticulous wound cleaning. Rinse the wound with saline to remove surface dirt, necrotic tissue and secretions.

[0078] Step S200: Determine whether the operation time of the power module 70 meets the preset operation time, and control the power module 70 to shut down.

[0079] It is understandable that the preset running time may be different depending on the treatment type and wound surface condition. For example, for a smaller wound surface, the preset running time may be shorter, while for a larger or deeper wound surface, the preset running time may be longer. A timer or counter is built into the power module 70 or the control module 60 to accurately record the running time of the power module.

[0080] When it is determined that the operation time of the power module 70 meets the preset operation time, the system should automatically trigger the shutdown mechanism to stop supplying power to the positive electrode 21 and the negative electrode 22. For example, a timer interrupt is set in the controller, and when the timer reaches the preset time, the shutdown operation is performed. In addition to the automatic shutdown mechanism, a manual shutdown function should also be provided so that the operator can manually shut down the power module 70 in an emergency or after the treatment is completed. The manual shutdown function should be easy to operate and can reliably stop the operation of the power module 70 at any time.

[0081] See also Fig. 9 The control method of the plasma treatment device provided by the embodiment of the present invention also includes step S300, step S400 and step S500.

[0082] Step S300: Acquire temperature and humidity information of the wound surface.

[0083] It is understandable that a temperature and humidity sensor can be integrated on the flexible plasma patch, and the temperature and humidity sensor is electrically connected to the control module 60. When the flexible plasma patch is in direct contact with the wound surface, the temperature and humidity sensor is used to collect temperature and humidity information of the wound surface, and feed the collected temperature and humidity information back to the control module 60.

[0084] Step S400: When it is determined that the humidity information of the wound surface is greater than the preset humidity information and the temperature information is less than the preset temperature information, the heating element 100 is controlled to operate; until the humidity information of the wound surface meets the preset humidity information, the heating element 100 is controlled to stop operating.

[0085] It is understandable that when the humidity of the wound surface is high and the temperature is not high, the heating element 100 can be controlled by the control module 60 to work, thereby quickly drying the wound surface and facilitating subsequent treatment.

[0086] Step S500: When it is determined that the humidity information of the wound surface is greater than the preset humidity information and the temperature information is greater than or equal to the preset temperature information, the heating element 100 is controlled to stop running, and the natural airflow through the through hole quickly dries the wound surface.

[0087] It is understandable that when the humidity of the wound surface is high and the temperature is high, the wound surface can be dried quickly by the natural airflow through the through hole without passing through the heating element 100, thereby avoiding scalding of the wound tissue.

[0088] The method provided by the present invention achieves the effects of sterilizing the wound surface, promoting healing, etc. by generating low-temperature plasma, and has a better treatment effect.

[0089] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A plasma treatment device, characterized in that: include: A flexible plasma patch comprises a first dielectric barrier layer, an electrode layer, a second dielectric barrier layer and a medical film layer stacked in sequence from top to bottom, wherein the medical film layer is suitable for contacting a wound surface, the electrode layer comprises a positive electrode, a negative electrode and an auxiliary electrode, the positive electrode and the negative electrode are coplanarly arranged on a substrate, and the auxiliary electrode is connected to the negative electrode to change the electric field distribution; A power module, electrically connected to the positive electrode and the negative electrode; The control module is connected to the power module and is used to control the operation of the power module.

2. The plasma treatment device according to claim 1, characterized in that: It also includes a power regulation module, which is electrically connected to the power module and the control module respectively, and is used to receive control instructions from the control module and control the output power of the power module.

3. The plasma treatment device according to claim 1, characterized in that: The flexible plasma patch further includes a switching component, which is integrally connected to the electrode wires of the positive electrode and the negative electrode and is electrically connected to the power module.

4. The plasma treatment device according to claim 1, characterized in that: The flexible plasma patch further comprises a heating element, wherein the heating element is located between the second dielectric barrier layer and the medical film layer, and the heating element is electrically connected to the power module.

5. The plasma treatment device according to claim 1, characterized in that: The flexible plasma patch also includes a monitoring module, which is arranged between the second dielectric barrier layer and the medical film layer and is used to monitor the temperature and humidity of the wound surface. The monitoring module is electrically connected to the control module.

6. The plasma treatment device according to any one of claims 1 to 5, characterized in that: The first dielectric barrier layer is provided with first through holes at intervals, and the first through holes are arranged corresponding to the gaps between the electrode layers; The second dielectric barrier layer is provided with second through holes at intervals, and the positions of the second through holes correspond to the positions of the first through holes; The medical film layer is provided with a third through hole, and the position of the third through hole corresponds to the position of the second through hole.

7. The plasma treatment device according to claim 6, characterized in that: Along the thickness direction of the flexible plasma patch, the apertures of the first through hole, the second through hole and the third through hole gradually increase from top to bottom.

8. The plasma treatment device according to claim 6, characterized in that: The aperture of the first through hole is smaller than that of the second through hole, and the aperture of the second through hole is smaller than that of the third through hole.

9. A control method for a plasma treatment device according to any one of claims 1 to 8, characterized in that: The steps include: When it is determined that the wound surface meets the treatment conditions, the power supply module is controlled to turn on to supply power to the positive electrode and the negative electrode, so as to form plasma between the positive electrode and the negative electrode to treat the wound surface; Determine that the operation time of the power module meets the preset operation time, and control the power module to shut down.

10. The control method of the plasma treatment device according to claim 9, characterized in that: The following steps are also included: Obtain temperature and humidity information of the wound surface; When it is determined that the humidity information of the wound surface is greater than the preset humidity information and the temperature information is less than the preset temperature information, the heating element is controlled to operate; until the humidity information of the wound surface meets the preset humidity information, the heating element is controlled to stop operating; When it is determined that the humidity information of the wound surface is greater than the preset humidity information, and the temperature information is greater than or equal to the preset temperature information, the heating element is controlled to stop running, and the wound surface is quickly dried by the natural airflow through the through hole.

Images