Thrombus removing catheter and removing method

Abstract

The invention discloses a thrombus removing catheter and a thrombus removing method, and belongs to the technical field of cardiovascular treatment instruments. Comprising a hollow catheter, a sealing plug is arranged in the end, acting on the interior of a blood vessel, of the catheter, the outer wall of the sealing plug is fixed to the inner wall of the catheter, a core tube is arranged in the catheter, and the outer surface of the core tube is slidably connected to the middle of the sealing plug; a flow gap is formed between the outer surface of the core pipe and the inner wall of the guide pipe, the two ends of the core pipe are arranged on the outer sides of the two ends of the guide pipe, a hollow guide column is arranged above the surface, close to the outside, of the sealing plug, and the inner surface of the guide column is fixed to the outer surface of the core pipe. The guide column comprises a cylindrical end and a conical end which are spliced, a plurality of guide sliding grooves which are evenly distributed in the circumference are formed in the outer surface of the guide column, and the guide sliding grooves are distributed in the cylindrical end and the conical end. According to the technical scheme, the injection effect of the thrombolysis liquid medicine is improved, the thrombolysis time is shortened, and the thrombolysis efficiency is improved.

Description

Technical Field

[0001] The present invention belongs to the technical field of cardiovascular treatment equipment, and in particular relates to a thrombus removal catheter and a removal method. Background Art

[0002] Vascular embolism is a common symptom among vascular diseases, and its disability and mortality rates are extremely high. Currently, the main treatments for this type of disease include mechanical thrombectomy and drug thrombolysis.

[0003] In the prior art, when injecting thrombolytic drugs into a blood clot, the drug solution is usually released through the through hole on the outer wall of the catheter, and the released drug solution can only contact the outer surface of the blood clot. For example, patent No. 202411479565.2 discloses a thrombolytic and thrombectomy device, which includes a spray tube, a core tube, an elastic skeleton, and a blood clot collection structure. When releasing the drug solution in this patent, the release method is consistent with that in the prior art, resulting in the drug solution only being in contact with the outer surface of the blood clot, which results in a long thrombolytic time and low thrombolytic efficiency. Summary of the invention

[0004] In view of this, the object of the present invention is to provide a thrombus removal catheter and a removal method, so as to improve the injection effect of thrombolytic solution, reduce the thrombolysis time, and improve the thrombolytic efficiency.

[0005] In order to achieve the above object, the present invention provides the following technical solutions:

[0006] The present invention provides a thrombus removal catheter, comprising a hollow catheter, wherein a sealing plug is provided inside one end of the catheter acting on the inside of a blood vessel, the outer wall of the sealing plug is fixed to the inner wall of the catheter, a core tube is provided inside the catheter, the outer surface of the core tube is slidably connected to the middle part of the sealing plug, and a flow gap is provided between the outer surface of the core tube and the inner wall of the catheter, both ends of the core tube are arranged outside the two ends of the catheter, a hollow guide column is provided above a surface of the sealing plug close to the outside, the inner surface of the guide column is fixed to the outer surface of the core tube, the guide column comprises a spliced ​​cylindrical end and a conical end, a plurality of circumferentially uniformly distributed guide grooves are provided on the outer surface of the guide column, the guide grooves are distributed on the cylindrical end and the conical end, and the conical end is close to the outer surface of the core tube. The catheter is arranged at one end located in the outside world, and a plurality of injection ejectors arranged side by side are arranged in the guide slide groove. The interior of the injection ejector is hollow, and one end of the injection ejector is slidably connected to the guide slide groove, and the other end of the injection ejector is slidably connected to the outer wall of the catheter. The catheter is provided with a first developing ring and a second developing ring, and the first developing ring and the second developing ring are arranged on the outside of both ends of the sliding connection part between the catheter and the injection ejector. An injection joint is provided on the surface of the catheter at the end located in the outside world, and the injection joint is communicated with the interior of the catheter. The injection ejector is used to be inserted into the interior of the thrombus block, and the injection joint is used to inject thrombolytic solution into the interior of the catheter. The thrombolytic solution flows from the flow gap to the injection ejector, flows out from the thrombolytic solution, and is injected into the thrombus block.

[0007] Furthermore, a plurality of circumferentially distributed auxiliary liquid inlet holes are provided on the outer wall of one end of the injection ejector located in the guide chute, and a wedge-shaped tip is provided on the other end of the injection ejector.

[0008] Furthermore, a columnar magnetic element is provided above the conical end of the guide column, the middle part of the columnar magnetic element is fixed on the core tube, one end of the guide slide extends to the columnar magnetic element, and when the end of the injection ejector pin is magnetically adsorbed in the guide slide on the columnar magnetic element, the other end of the injection ejector pin is located within the wall thickness of the catheter.

[0009] Furthermore, a sliding ball head is provided on one end of the injection ejector facing the guide slot, and the diameter of the sliding ball head is greater than the diameter of the injection ejector.

[0010] Furthermore, a first stopper is provided on one end of the core tube that acts on the blood vessel, an elastic airbag is provided between the first stopper and the end of the catheter, one end of the elastic airbag is fixed on the first stopper, the middle part of the elastic airbag is slidably connected to the core tube, a first magnetic ring is provided on the other end of the elastic airbag, the first magnetic ring is slidably set on the core tube, and the surface of the first magnetic ring is fixed on the elastic airbag, a second magnetic ring is provided on the end of the catheter, and the first magnetic ring and the second magnetic ring are set to repel each other.

[0011] Furthermore, a second stopper is provided on one end of the catheter located outside the blood vessel, and the core tube is slidably connected to the middle part of the second stopper.

[0012] Furthermore, an outer tube is sleeved on the outer side of the catheter, a blocking end is provided on one end of the outer tube located in the blood vessel, and a negative pressure component is provided on one end of the outer tube located outside the blood vessel.

[0013] A method for removing thrombus using a thrombus removal catheter comprises the following steps:

[0014] S1. inserting the catheter into the blood vessel and passing through the thrombus in the blood vessel so that the thrombus is located between the first developing ring and the second developing ring;

[0015] S2, the core tube is pulled outward, and the guide column slides outward together with the core tube, that is, the injection ejector slides in the guide slot, so that the end of the injection ejector is ejected outward, and the injection ejector is inserted into the thrombus block; at the same time, when the core tube is pulled outward, the positions of the first magnetic ring and the second magnetic ring are close, and under the effect of mutual repulsion, the first magnetic ring will slide on the core tube, thereby squeezing the elastic airbag to expand it, and temporarily blocking the blood vessel;

[0016] S3, injecting thrombolytic solution into the injection connector, causing the solution to flow out from the end of the injection needle, so that the thrombolytic solution is injected into the thrombus;

[0017] S4. After the thrombus is dissolved, negative pressure is generated in the outer tube to suck the dissolved thrombus out of the blood vessel;

[0018] S5. Slide the core tube back to its original position to reset the elastic airbag and injection needle, and then pull out the catheter.

[0019] The beneficial effects of the present invention are:

[0020] This technical solution can inject thrombolytic solution into the interior of the thrombus, so that the thrombus begins to dissolve from the inside, thereby improving the dissolution effect and dissolution efficiency, and improving the thrombolytic effect.

[0021] Other advantages, objectives and features of the present invention will be described in the following description and will be apparent to those skilled in the art to some extent, or those skilled in the art may be taught from the practice of the present invention. The objectives and other advantages of the present invention may be realized and obtained through the following description. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to make the purpose, technical solution and beneficial effects of the present invention clearer, the present invention provides the following drawings for illustration:

[0023] Figure 1It is a three-dimensional schematic diagram of the thrombus removal catheter of the present invention in a working state;

[0024] Figure 2 It is a partial schematic diagram of the injection ejector part of the thrombus removal catheter of the present invention when it is in a working state;

[0025] Figure 3 It is a three-dimensional schematic diagram of the injection ejector part of the thrombus removal catheter of the present invention in a working state;

[0026] Figure 4 It is a three-dimensional schematic diagram from another perspective when the injection ejector needle part of the thrombus removal catheter of the present invention is in a working state;

[0027] Figure 5 It is a schematic diagram of the internal cross-sectional view of the thrombus removal catheter of the present invention when it is in a working state;

[0028] Figure 6 The figure is a schematic diagram of the installation positions of the sealing plug and the guide column in the thrombus removal catheter of the present invention.

[0029] The following are marked in the accompanying drawings:

[0030] 1. Catheter; 2. Core tube; 3. Sealing plug; 4. Flow gap; 5. Guide column; 6. Guide chute; 7. Injection ejector pin; 8. Auxiliary liquid inlet hole; 9. Columnar magnetic element; 10. First stopper; 11. Elastic airbag; 12. First magnetic ring; 13. Second magnetic ring; 14. Injection connector; 15. Second stopper; 16. First developing ring; 17. Second developing ring; 18. Outer tube; 19. Sealing end; 20. Thrombus block. DETAILED DESCRIPTION

[0031] like Figure 1 to Figure 6As shown, a thrombus removal catheter of the present invention comprises a hollow catheter 1, and a sealing plug 3 is arranged inside the end of the catheter 1 acting on the inside of the blood vessel. The function of the sealing plug 3 is to prevent excessive thrombolytic solution from flowing out of the gap between the catheter 1 and the core tube 2. The sealing plug 3 can be a rubber part, and the outer wall of the sealing plug 3 is fixed on the inner wall of the catheter 1. A core tube 2 is arranged inside the catheter 1, and the outer surface of the core tube 2 is slidably connected to the middle part of the sealing plug 3, and a flow gap 4 is arranged between the outer surface of the core tube 2 and the inner wall of the catheter 1, and both ends of the core tube 2 are arranged on the outside of the two ends of the catheter 1, and a hollow guide column 5 is arranged above a surface of the sealing plug 3 close to the outside, and the inner surface of the guide column 5 is fixed to the outer surface of the core tube 2, and the guide column 5 includes a spliced ​​cylindrical end and a conical end, and a plurality of circumferentially uniformly distributed guide grooves 6 are arranged on the outer surface of the guide column 5, and the depth of the guide grooves 6 is consistent. The guide grooves 6 are distributed on the cylindrical end and the conical end, and the conical end is close to the end of the catheter 1 located at the outside. The guide slot 6 is provided with a plurality of injection ejectors 7 arranged side by side, the interior of the injection ejector 7 is hollow, one end of the injection ejector 7 is slidably connected to the guide slot 6, and the other end of the injection ejector 7 is slidably connected to the outer wall of the catheter 1. The outer wall of the catheter 1 is provided with through holes having the same number as the injection ejectors 7. The catheter 1 is provided with a first developing ring 16 and a second developing ring 17 (metal rings made of platinum-iridium alloy, fixed in the form of forging, and capable of developing under radiation irradiation), the first developing ring 16 and the second developing ring 17 are arranged on the outer sides of both ends of the sliding connection portion between the catheter 1 and the injection ejector 7, an injection connector 14 is provided on the surface of the catheter 1 at one end thereof, the injection connector 14 is communicated with the interior of the catheter 1, the injection ejector 7 is used for inserting into the interior of the thrombus block 20, the injection connector 14 is used for injecting thrombolytic solution into the interior of the catheter 1, the thrombolytic solution flows from the flow gap 4 to the injection ejector 7, flows out from the thrombolytic solution, and is injected into the thrombus block 20.

[0032] The working principle of the above technical solution is:

[0033] The guide pin 5 is then pulled outward to move the guide pin 5 from the guide slot 6 on the cylindrical end, and the end of the injection pin 7 is pushed outward to insert the injection pin 7 into the thrombus block 20. Of course, it is not difficult to understand that the thrombolytic solution may also flow out from the gap between the catheter 1 and the core tube 2, and after flowing out, it can act on the surface of the thrombus 20, thereby dissolving the inside and outside of the thrombus 20 at the same time, further improving the thrombus removal effect and rate.

[0034] Of course, it is not difficult to understand that the length of the injection needle 7 should be relatively short, so as not to puncture a blood vessel after being extended, and no further elaboration is made here.

[0035] In one practicable manner, a plurality of circumferentially distributed auxiliary liquid inlet holes 8 are provided on the outer wall of one end of the injection ejector pin 7 located in the guide chute 6, and a wedge-shaped tip is provided on the other end of the injection ejector pin 7. The contact between the end of the injection ejector pin 7 and the guide chute 6 may cause the end to be contacted and closed. Therefore, the provision of the auxiliary liquid inlet holes 8 can ensure the normal liquid inlet of the injection ejector pin 7. At the same time, the wedge-shaped tip can be understood as the needle tip part of the syringe, thereby improving the effect of puncturing the blood clot.

[0036] In one practicable manner, a columnar magnetic element 9 (magnet) is provided above the conical end of the guide column 5, the middle portion of the columnar magnetic element 9 is fixed to the core tube 2, one end of the guide chute 6 extends to the columnar magnetic element 9, and when the end of the injection ejector pin 7 is magnetically adsorbed in the guide chute on the columnar magnetic element 9, the other end of the injection ejector pin 7 is located within the wall thickness of the catheter 1.

[0037] When the catheter 1 is in a normal state, the end of the injection thimble 7 is adsorbed on the columnar magnetic element 9, which prevents the injection thimble 7 from extending out of the catheter 1, causing inconvenience in use. At the same time, when the core tube 2 slides outward, the position of the injection thimble 7 is limited by the through hole set on the catheter 1 and will not move horizontally. Therefore, it can only move with the guide chute 6 to realize the operation of the injection thimble 7 being ejected. After the thrombolysis is completed, it is only necessary to reset the core tube 2, thereby driving the guide column 5 to reset, and then the annular magnetic element will adsorb the end of the injection thimble 7, so that the injection thimble 7 is retracted, which is convenient for the subsequent removal of the catheter 1. Of course, the part of the injection thimble 7 protruding from the catheter 1 and the part located in the catheter 1 are relatively short. Because the diameter of the blood vessel is small, the attached figure is only for the convenience of observation, and the size is relatively too large after being drawn.

[0038] In an practicable manner, a sliding ball head is provided on one end of the injection ejector needle 7 facing the guide slot 6 . The diameter of the sliding ball head is larger than the diameter of the injection ejector needle 7 . The sliding ball head limits the injection ejector needle 7 to prevent it from falling out of the catheter 1 .

[0039] In one feasible manner, a first stopper 10 is provided on one end of the core tube 2 acting in the blood vessel, an elastic airbag 11 is provided between the first stopper 10 and the end of the catheter 1, the elastic airbag 11 is annular, one end of the elastic airbag 11 is fixed on the first stopper 10, the middle part of the elastic airbag 11 is slidably connected to the core tube 2, a first magnetic ring 12 is provided on the other end of the elastic airbag 11, the first magnetic ring 12 is slidably set on the core tube 2, and the surface of the first magnetic ring 12 is fixed on the elastic airbag 11, a second magnetic ring 13 is provided at the end of the catheter 1, and the first magnetic ring 12 and the second magnetic ring 13 are mutually exclusive.

[0040] When the core tube 2 is pulled outward, the first magnetic ring 12 will move close to the second magnetic ring 13, and then under the repulsion of the two, the first magnetic ring 12 will move on the core tube 2, and then squeeze the elastic airbag 11, and then the elastic airbag 11 will deform, filling and blocking the blood vessel to prevent the dissolved thrombus 20 from flowing in the blood vessel. Of course, after the thrombolysis is completed, the core tube 2 is reset, so that the first magnetic ring 12 loses the force of the second magnetic ring 13, and the elastic airbag 11 will be reset.

[0041] In one practicable manner, a second stopper 15 is provided on one end of the catheter 1 outside the blood vessel, and the core tube 2 is slidably connected to the middle of the second stopper 15 to further prevent the thrombolytic solution from flowing out of the end of the catheter 1 .

[0042] In an practicable manner, an outer tube 18 is sleeved on the outer side of the catheter 1, and a blocking end 19 is provided on one end of the outer tube 18 located in the blood vessel, and a negative pressure component is provided on one end of the outer tube 18 located outside the blood vessel. The negative pressure component provides negative pressure to suck out the blood vessel, thereby sucking out the dissolved thrombus 20 and a small amount of blood. Of course, the blocking section can be understood as an annular hollow elastic component, and the expansion or reset can be controlled by air pressure.

[0043] A method for removing thrombus using a thrombus removal catheter 1 comprises the following steps:

[0044] S1, inserting the catheter 1 into the blood vessel and passing through the thrombus 20 in the blood vessel, so that the thrombus 20 is located between the first developing ring 16 and the second developing ring 17;

[0045] S2, the core tube 2 is pulled outward, and the guide column 5 slides outward together with the core tube 2, that is, the injection ejector 7 slides in the guide slot 6, so that the end of the injection ejector 7 is ejected outward, and the injection ejector 7 is inserted into the thrombus block 20; at the same time, when the core tube 2 is pulled outward, the positions of the first magnetic ring 12 and the second magnetic ring 13 are close, and under the effect of mutual repulsion, the first magnetic ring 12 will slide on the core tube 2, thereby squeezing the elastic airbag 11 to expand it, and temporarily blocking the blood vessel;

[0046] S3, injecting thrombolytic solution into the injection connector 14, so that the solution flows out from the end of the injection needle 7, and the thrombolytic solution is injected into the thrombus 20;

[0047] S4, after the thrombus is dissolved, negative pressure is generated in the outer tube 18, and the dissolved thrombus 20 is sucked out of the blood vessel;

[0048] S5, the core tube 2 is slid back to its original position, so that the elastic airbag 11 and the injection ejector needle 7 are reset, and then the catheter 1 is withdrawn.

[0049] Finally, it should be noted that the above preferred embodiments are only used to illustrate the technical solutions of the present invention rather than to limit it. Although the present invention has been described in detail through the above preferred embodiments, those skilled in the art should understand that various changes can be made in form and details without departing from the scope defined by the claims of the present invention.

Claims

1. A thrombus removal catheter, characterized in that: The invention comprises a hollow catheter (1), wherein a sealing plug (3) is arranged inside one end of the catheter (1) acting on the inside of a blood vessel, the outer wall of the sealing plug (3) is fixed on the inner wall of the catheter (1), a core tube (2) is arranged inside the catheter (1), the outer surface of the core tube (2) is slidably connected to the middle part of the sealing plug (3), and a flow gap (4) is arranged between the outer surface of the core tube (2) and the inner wall of the catheter (1), both ends of the core tube (2) are arranged outside the two ends of the catheter (1), a hollow guide column (5) is arranged above a surface of the sealing plug (3) close to the outside, the inner surface of the guide column (5) is fixed on the outer surface of the core tube (2), the guide column (5) comprises a spliced ​​cylindrical end and a conical end, a plurality of circumferentially evenly distributed guide grooves (6) are arranged on the outer surface of the guide column (5), the guide grooves (6) are distributed on the cylindrical end and the conical end, the conical end is arranged close to the end of the catheter (1) located in the outside, and the guide column (5) is provided with a plurality of circumferentially evenly distributed guide grooves (6) on the outer surface. A plurality of injection ejectors (7) are arranged side by side in the guide chute (6). The interior of the injection ejector (7) is hollow. One end of the injection ejector (7) is slidably connected to the guide chute (6). The other end of the injection ejector (7) is slidably connected to the outer wall of the catheter (1). The catheter (1) is provided with a first developing ring (16) and a second developing ring (17). The first developing ring (16) and the second developing ring (17) are arranged on the outer sides of the two ends of the sliding connection portion between the catheter (1) and the injection ejector (7). An injection joint (14) is provided on the surface of the catheter (1) at one end located at the outside. The injection joint (14) is communicated with the interior of the catheter (1). The injection ejector (7) is used to be inserted into the interior of the thrombus block (20). The injection joint (14) is used to inject thrombolytic solution into the interior of the catheter (1). The thrombolytic solution flows from the flow gap (4) to the injection ejector (7), flows out from the thrombolytic solution, and is injected into the thrombus block (20).

2. A thrombus removal catheter according to claim 1, characterized in that: A plurality of auxiliary liquid inlet holes (8) distributed circumferentially are provided on the outer wall of one end of the injection ejector needle (7) located in the guide chute (6), and a wedge-shaped tip is provided on the other end of the injection ejector needle (7).

3. The thrombus removal catheter according to claim 1, characterized in that: A columnar magnetic element (9) is provided above the conical end of the guide column (5), the middle part of the columnar magnetic element (9) is fixed on the core tube (2), one end of the guide slide (6) extends to the columnar magnetic element (9), and when the end of the injection ejector pin (7) is magnetically adsorbed in the guide slide on the columnar magnetic element (9), the other end of the injection ejector pin (7) is located within the wall thickness of the catheter (1).

4. The thrombus removal catheter according to claim 1, characterized in that: A sliding ball head is provided on one end of the injection ejector needle (7) facing the guide slot (6), and the diameter of the sliding ball head is greater than the diameter of the injection ejector needle (7).

5. The thrombus removal catheter according to claim 1, characterized in that: A first stopper (10) is provided on one end of the core tube (2) acting on the blood vessel, an elastic airbag (11) is provided between the first stopper (10) and the end of the catheter (1), one end of the elastic airbag (11) is fixed on the first stopper (10), the middle part of the elastic airbag (11) is slidably connected to the core tube (2), a first magnetic ring (12) is provided on the other end of the elastic airbag (11), the first magnetic ring (12) is slidably arranged on the core tube (2), and the surface of the first magnetic ring (12) is fixed on the elastic airbag (11), and a second magnetic ring (13) is provided at the end of the catheter (1), and the first magnetic ring (12) and the second magnetic ring (13) are arranged to repel each other.

6. The thrombus removal catheter according to claim 1, characterized in that: A second stopper (15) is provided on one end of the catheter (1) located outside the blood vessel, and the core tube (2) is slidably connected to the middle part of the second stopper (15).

7. The thrombus removal catheter according to claim 1, characterized in that: An outer tube (18) is also sleeved on the outer side of the catheter (1); a blocking end (19) is provided on the end of the outer tube (18) located inside the blood vessel, and a negative pressure component is provided on the end of the outer tube (18) located outside the blood vessel.

8. A method for removing thrombus using a thrombus removal catheter according to any one of claims 1 to 7, characterized in that: The cleanup steps include: S1, inserting the catheter (1) into a blood vessel and passing through a thrombus (20) in the blood vessel, so that the thrombus (20) is located between the first developing ring (16) and the second developing ring (17); S2, the core tube (2) is pulled outward, and the guide column (5) slides outward together with the core tube (2), that is, the injection ejector pin (7) slides in the guide slot (6), so that the end of the injection ejector pin (7) is ejected outward, so that the injection ejector pin (7) is inserted into the inside of the thrombus (20); at the same time, when the core tube (2) is pulled outward, the positions of the first magnetic ring (12) and the second magnetic ring (13) are close, and under the effect of mutual repulsion, the first magnetic ring (12) slides on the core tube (2), thereby squeezing the elastic airbag (11) to expand it, and temporarily blocking the blood vessel; S3, injecting a thrombolytic solution into the injection connector (14), causing the solution to flow out from the end of the injection needle (7), and injecting the thrombolytic solution into the thrombus (20); S4, after the thrombus is dissolved, negative pressure is generated in the outer tube (18), and the dissolved thrombus (20) is sucked out of the blood vessel; S5, the core tube (2) is slid back to its original position, so that the elastic airbag (11) and the injection ejector needle (7) are reset, and then the catheter (1) is withdrawn.

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