Laser ablation method and laser ablation device

By using laser mediated caps in laser soft tissue ablation technology, laser energy is converted into thermal energy to ablate tissue, the problem of optical fibers being susceptible to contamination and limited ablation range is solved, the stable transmission of laser power and the expansion of ablation range is achieved, and the efficacy and safety of treatment are improved.

CN119770164APending Publication Date: 2025-04-08BEIJING MEDICAL PLASMA LABORATORY TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202411901935.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-23
Publication Date
2025-04-08

AI Technical Summary

Technical Problem

In the existing laser soft tissue ablation technology, the end of the optical fiber is directly in contact with the lesion tissue and is easily contaminated, resulting in a decrease in laser power; the high laser power density leads to tissue carbonization; the inner core size of the optical fiber limits the ablation range.

Method used

The laser-mediated cap is used to heat the laser-mediated cap to ablation temperature by transporting the laser through the optical fibers, and maintain the laser-mediated cap temperature to achieve laser ablation of the ablation target.

Benefits of technology

It avoids direct contact between optical fibers and tissues, prevents tissue contamination, ensures stable transmission of laser power, expands the ablation range, avoids tissue carbonization, and improves the efficacy and safety of treatment.

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Abstract

The invention relates to the technical field of medical equipment, in particular to a laser ablation method and a laser ablation device. The laser ablation host is controlled to output laser based on the ablation temperature, the laser is transmitted through the optical fiber to act on the laser mediating cap, and the laser mediating cap is heated to the ablation temperature; and the laser ablation host is kept outputting laser, so that the laser mediation cap maintains the ablation temperature, and laser ablation is performed on the ablation target by using the laser mediation cap. The laser-mediated cap is arranged between the focus soft tissue and the light-guide fiber, so that the working end of the light-guide fiber is prevented from being in direct contact with the in-vivo tissue, the pollution of the human tissue to the light-guide fiber is prevented, the ablation range is expanded, tissue carbonization is avoided, accurate, efficient and safe ablation of the soft tissue lesion is realized, and the ablation efficiency is improved. The efficiency of laser ablation treatment is improved, meanwhile, the safety of treatment is greatly improved, and the risks of tissue overheating and carbonization possibly occurring in the treatment process are reduced.
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Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to a laser ablation method and a laser ablation device. Background Art

[0002] Laser soft tissue ablation uses the photothermal effect of laser. When the laser is absorbed by soft tissue, the light energy is converted into heat energy, causing the temperature of the tissue to rise, which in turn causes the tissue to evaporate or coagulate, thereby achieving the purpose of cutting or removing the tissue. Specifically, the puncture needle is inserted into the lesion in the body under ultrasound guidance, and then the end of the optical fiber is pushed along the needle hole of the puncture needle to the lesion. The puncture needle is then withdrawn a distance away from the lesion, leaving only the end of the optical fiber in the lesion. At this time, the end of the optical fiber is completely wrapped in the lesion tissue, and the laser reaches the lesion through the optical fiber to start ablation treatment of the lesion.

[0003] In clinical practice, laser soft tissue ablation technology still faces many defects. First, because the end of the optical fiber is in direct contact with the lesion tissue, it is easily contaminated, and the contaminated optical fiber will affect the output of the laser power, resulting in a decrease in the output power of the laser. Secondly, the laser power density output by the optical fiber is extremely high, causing the soft tissue to carbonize due to the high local temperature at the contact point between the end of the optical fiber and the soft tissue, forming a hard carbonized shell, which not only hinders the penetration of the laser into deep tissues, but may also damage surrounding healthy tissues. Thirdly, the limitation of the size of the inner core of the optical fiber also reduces the scope of ablation, which limits the widespread application of the technology. Summary of the invention

[0004] The present invention provides a laser ablation method and a laser ablation device, which are used to solve the many defects faced by the laser soft tissue ablation technology in the prior art, ensure the stable power transmission of the laser, avoid tissue carbonization, and expand the ablation range.

[0005] The present invention provides a laser ablation method, comprising: obtaining the ablation temperature of the ablation target based on the ablation target; based on the ablation temperature, controlling the laser ablation host to output laser, and transmitting the laser to a laser-mediated cap through an optical fiber to heat the laser-mediated cap to the ablation temperature; maintaining the laser ablation host to output laser so that the laser-mediated cap maintains the ablation temperature, and using the laser-mediated cap to perform laser ablation on the ablation target.

[0006] According to a laser ablation method provided by the present invention, maintaining the laser ablation host to output laser so that the laser-mediated cap maintains the ablation temperature includes: acquiring the real-time temperature of the laser-mediated cap; and adjusting the power of the laser output by the laser ablation host based on the acquired real-time temperature of the laser-mediated cap to reheat the laser-mediated cap to the ablation temperature.

[0007] According to a laser ablation method provided by the present invention, the use of the laser-mediated cap to perform laser ablation on the ablation target includes: obtaining the ablation time of the ablation target based on the ablation target; based on the ablation time, controlling the laser-mediated cap to perform an ablation operation on the ablation target for the ablation time at the ablation temperature to complete laser ablation of the ablation target.

[0008] The present invention also provides a laser ablation device, which is suitable for executing any one of the laser ablation methods described above, and the laser ablation device includes a laser ablation host, an optical fiber and a laser mediation cap, wherein the laser ablation host is used to generate laser, and the laser ablation host is provided with an optical fiber connection port for outputting laser; the optical fiber is used to transmit the laser generated by the laser ablation host, and the first end of the optical fiber is connected to the optical fiber connection port; the laser mediation cap is connected to the second end of the optical fiber, and is suitable for outputting laser through the optical fiber to act on the laser mediation cap to heat the laser mediation cap.

[0009] According to a laser ablation device provided by the present invention, the laser ablation host includes a laser generating mechanism, a control module, an adjustment module, a temperature feedback module and a setting module, wherein the laser generating mechanism is used to generate ablation laser; the control module is electrically connected to the laser generating mechanism, and is used to control the power of the laser emitted by the laser generating mechanism; the adjustment module is electrically connected to the control module, and is used to control the power of the laser emitted by the laser generating mechanism through the control module; the temperature feedback module is electrically connected to the control module, and is used to monitor the temperature of the laser mediation cap and feed back to the control module; the setting module is electrically connected to the control module to limit the working temperature of the laser mediation cap and the working time and the emitted laser power of the laser generating mechanism.

[0010] According to a laser ablation device provided by the present invention, the laser ablation host further comprises a shell, and the shell is provided with a setting panel, an adjustment panel and a display panel.

[0011] The setting panel is electrically connected to the setting module and is used to set the working temperature of the laser mediation cap, the working time of the laser generating mechanism and the emitted laser power.

[0012] The adjustment panel is electrically connected to the adjustment module and is used for adjusting the power of the laser emitted by the laser generating mechanism.

[0013] The display panel is electrically connected to the control module, and includes a set working display area and a real-time working display area. The set working display area is used to display the set temperature of the laser mediation cap, the set working time of the laser generating mechanism, and the set power of the laser emitted by the laser generating mechanism; the real-time working display area is used to display the real-time temperature of the laser mediation cap, the real-time working time of the laser generating mechanism, and the real-time power of the laser emitted by the laser generating mechanism.

[0014] According to a laser ablation device provided by the present invention, the optical fiber includes an optical fiber inner core and an optical fiber jacket wrapped around the outer circumference of the optical fiber inner core, the laser mediation cap is connected to the end of the optical fiber jacket, and the working end of the optical fiber inner core extends out of the end of the optical fiber jacket and is located in the laser mediation cap.

[0015] According to a laser ablation device provided by the present invention, a plurality of temperature sensors are evenly distributed on the laser-mediated cap, and the temperature sensors are used to monitor the real-time temperature of the laser-mediated cap; the inner wall of the laser-mediated cap forms a diffuse reflection inner wall.

[0016] According to a laser ablation device provided by the present invention, a beam expander is arranged in the laser-mediated cap, and the beam expander is located at the working end of the optical fiber. The beam expander is arranged parallel to the bottom end surface of the laser-mediated cap to expand the laser output from the working end of the optical fiber so that the expanded laser acts on the bottom end surface of the laser-mediated cap.

[0017] According to a laser ablation device provided by the present invention, a beam splitter is arranged in the laser-mediated cap, and the beam splitter is located at the working end of the optical fiber. The beam splitter is used to uniformly diverge the laser output from the working end of the optical fiber so that the diverged laser acts on the inner wall of the laser-mediated cap.

[0018] The laser ablation method and laser ablation device provided by the present invention use a laser-mediated cap to mediate laser ablation treatment of soft tissue in the body, thereby avoiding direct contact between the working end of the optical fiber and the tissue in the body, preventing human tissue from contaminating the optical fiber, and ensuring the stable transmission of laser power through the optical fiber. The area of ​​the laser-mediated cap can be hundreds of times the cross-sectional area of ​​the inner core of the optical fiber, expanding the ablation range and avoiding tissue carbonization. The laser ablation method of the present invention uses a laser-mediated cap between the lesion soft tissue and the optical fiber, optimizes the laser ablation treatment process, and achieves accurate, efficient and safe ablation of soft tissue lesions, which not only improves the effectiveness of laser ablation treatment, but also greatly improves the safety of treatment, and reduces the risk of tissue overheating and carbonization that may occur during treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions in the present invention or the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0020] Figure 1 It is a schematic flow chart of the laser ablation method provided by the present invention.

[0021] Figure 2 This is a block diagram of the working principle of the laser ablation host provided by the present invention.

[0022] Figure 3 It is a schematic diagram of the external structure of the laser ablation host provided by the present invention.

[0023] Figure 4 The present invention is a schematic diagram of an assembly structure of an optical fiber and a laser-mediated cap.

[0024] Figure 5 It is another schematic diagram of the assembly structure of the optical fiber and the laser-mediated cap provided by the present invention.

[0025] Figure 6 This is another schematic diagram of the assembly structure of the optical fiber and the laser-mediated cap provided by the present invention.

[0026] Figure numerals: 1. Laser ablation host; 11. Optical fiber connection port; 12. Laser generating mechanism; 13. Control module; 14. Adjustment module; 15. Temperature feedback module; 16. Setting module; 17. Shell; 171. Setting panel; 172. Adjustment panel; 173. Display panel; 2. Optical fiber; 21. Optical fiber inner core; 22. Optical fiber jacket; 3. Laser-mediated cap; 4. Beam expander; 5. Beam splitter. DETAILED DESCRIPTION

[0027] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the drawings of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0028] In the description of the embodiments of the present invention, it should be noted that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the embodiments of the present invention and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limitations on the embodiments of the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0029] In the description of the embodiments of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in the embodiments of the present invention can be understood according to specific circumstances.

[0030] In the embodiments of the present invention, unless otherwise clearly specified and limited, the first feature being "above" or "below" the second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0031] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the embodiment of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0032] Combine the following Figures 1 to 6 The laser ablation method and the laser ablation device of the present invention are described.

[0033] One embodiment of the present invention provides a laser ablation method, see Figure 1 As shown, the laser ablation method specifically includes the following steps S1 to S3.

[0034] S1. acquiring the ablation temperature of the ablation target based on the ablation target (the ablation temperature refers to the temperature reached when the ablation target is ablated, i.e., the temperature at which the tissue is evaporated or coagulated in the laser soft tissue ablation surgery); S2, based on the ablation temperature, controlling the laser ablation host 1 to output laser, and transmitting the laser to the laser mediation cap 3 through the optical fiber 2, so as to heat the laser mediation cap 3 to the ablation temperature; S3 , maintaining the laser ablation host 1 to output laser, allowing the laser mediation cap 3 to maintain the ablation temperature, and utilizing the laser mediation cap 3 to perform laser ablation on the ablation target.

[0035] The laser ablation method of this embodiment can be applied to laser soft tissue ablation surgery, with the lesion soft tissue as the ablation target. First, the ablation temperature of the lesion soft tissue is determined according to the lesion soft tissue, and the laser ablation host 1 is set; then, under the guidance of an imaging device (such as a CT or ultrasound device), the puncture needle is percutaneously punctured into the lesion site in the body, and then the optical fiber 2 equipped with a laser mediation cap 3 is inserted into the needle hole of the puncture needle and enters the lesion site along the puncture needle; the laser ablation host 1 is started to output Laser, the laser output by the laser ablation host 1 is transmitted through the optical fiber 2 and reaches the laser-mediated cap 3 at the working end of the optical fiber 2, converting the laser energy into heat energy to act on the laser-mediated cap 3. The laser-mediated cap 3 has good corrosion resistance, biocompatibility, mechanical strength and balanced thermal conductivity. After the laser heats the laser-mediated cap 3, the heat energy is evenly distributed on the laser-mediated cap 3. When the laser-mediated cap 3 is heated to the ablation temperature of the lesion soft tissue, the heat energy of the laser-mediated cap 3 performs thermal coagulation and ablation on the lesion soft tissue.

[0036] It is understandable that the laser-mediated cap 3 is used to mediate the laser for in vivo soft tissue ablation treatment, which avoids direct contact between the working end of the optical fiber 2 and the tissue in the body, prevents the human tissue from contaminating the optical fiber 2, and ensures the stable transmission of the laser power through the optical fiber 2. The area of ​​the laser-mediated cap 3 can be hundreds of times the cross-sectional area of ​​the inner core of the optical fiber 2, which expands the ablation range and avoids tissue carbonization. The laser ablation method of this embodiment uses the laser-mediated cap 3 between the lesion soft tissue and the optical fiber 2, optimizes the laser ablation treatment process, and realizes accurate, efficient and safe ablation of soft tissue lesions, which not only improves the effectiveness of laser ablation treatment, but also greatly improves the safety of treatment, and reduces the risk of tissue overheating and carbonization that may occur during treatment.

[0037] In some embodiments of the laser ablation method of the present invention, the process of maintaining the laser ablation host 1 to output laser so that the laser-mediated cap 3 maintains the ablation temperature in the above step S3 includes the following steps S31 and S32.

[0038] S31 , obtaining the real-time temperature of the laser-mediated cap 3 .

[0039] S32 . Based on the acquired real-time temperature of the laser-mediated cap 3 , the power of the laser output by the laser ablation host 1 is adjusted to reheat the laser-mediated cap 3 to the ablation temperature.

[0040] It can be understood that in the laser ablation method of this embodiment, the real-time temperature of the laser-mediated cap 3 is monitored during the laser ablation process, and the power of the laser output by the laser ablation host 1 is adjusted in real time to achieve precise control of the temperature of the laser-mediated cap 3 so as to maintain it at the ablation temperature of the lesion soft tissue, thereby ensuring that the temperature of the laser-mediated cap 3 is maintained within a preset safety range during the treatment process, thereby avoiding the problem of tissue carbonization caused by overheating.

[0041] Among them, the real-time temperature monitoring of the laser-mediated cap 3 can be achieved through a temperature sensor. Specifically, two optical fibers 2 can be set, one of which is used for the conduction and energy supply of the laser, and the other is used for the conduction of the temperature signal; or a conduction line can be added to the optical fiber 2, and the optical fiber 2 conducts the temperature signal through the conduction line during the laser conduction process. The real-time temperature of the laser-mediated cap 3 is first detected by a temperature sensor, and then the temperature signal is transmitted to the laser ablation host 1 by the optical fiber or conduction line used for temperature signal transmission, so as to facilitate subsequent power adjustment. Similarly, in some specific examples, the temperature monitoring process can also be performed directly through a thermocouple, and the thermocouple and the optical fiber 2 are prepared as one body, and the thermocouple's hot electrode is in the laser-mediated cap 3. The temperature of the laser-mediated cap 3 is monitored in real time through the thermocouple's hot electrode and transmitted to the laser ablation host 1.

[0042] In some embodiments of the laser ablation method of the present invention, the process of performing laser ablation on the ablation target by using the laser-mediated cap 3 in the above step S3 includes the following steps S301 and S302.

[0043] S301. Acquire an ablation time of an ablation target based on the ablation target.

[0044] S302 , based on the ablation time, controlling the laser-mediated cap 3 to perform an ablation operation on the ablation target at the ablation temperature for the ablation time, thereby completing laser ablation of the ablation target.

[0045] It is understandable that the laser ablation method of this embodiment can obtain the ablation time of the ablation target according to the ablation target before the operation. Specifically, the doctor's clinical surgical experience can be used to obtain the laser ablation time of the corresponding lesion soft tissue under a certain laser power, and then the laser ablation host 1 is controlled to output the laser of the corresponding power during the operation, and the corresponding laser ablation time is set in advance. During the operation, the laser output is performed according to the set laser output power and ablation time to realize the process of intelligent laser ablation of the lesion soft tissue. It should be understood that the ablation time can be the time when the laser ablation host 1 outputs the laser, and it can also be optimized to the time for ablation after the laser-mediated cap 3 reaches the ablation temperature. It can be continuously optimized and improved according to clinical surgical experience in order to obtain a better intelligent laser ablation process. During the laser ablation process, the laser ablation host 1 can also be adjusted according to the actual situation, and the power of the laser output by the laser ablation host 1 and the time for performing ablation can be adjusted to achieve a better treatment effect.

[0046] On the other hand, the present invention further provides a laser ablation device, which is suitable for executing the laser ablation method of any one of the above-mentioned embodiments. In some embodiments, the laser ablation device includes a laser ablation host 1, an optical fiber 2 and a laser mediation cap 3, wherein the laser ablation host 1 is used to generate laser, and the laser ablation host 1 is provided with an optical fiber connection port 11 for outputting laser; the optical fiber 2 is used to transmit the laser generated by the laser ablation host 1, and the first end of the optical fiber 2 is connected to the optical fiber connection port 11; the laser mediation cap 3 is connected to the second end of the optical fiber 2, and is suitable for outputting laser through the optical fiber 2 to act on the laser mediation cap 3, so as to heat the laser mediation cap 3.

[0047] It can be understood that the laser ablation host 1 generates laser light, which is transmitted to the optical fiber 2 through the optical fiber connection port 11. The optical fiber 2 transmits the laser light generated by the laser ablation host 1 to act on the laser mediation cap 3. The laser mediation cap 3 installed at the working end of the optical fiber 2 effectively and evenly converts the laser light energy into heat energy, avoiding tissue carbonization, and is used to accurately ablate human soft tissue lesions, ensuring the safety and effectiveness of the treatment process. At the same time, the laser mediation cap 3 also prevents the direct contact between the optical fiber 2 and the patient's body tissue, avoiding the contamination of the optical fiber 2 by human tissue, and ensuring the stable transmission of the laser power through the optical fiber 2.

[0048] In some embodiments of the laser ablation device of the present invention, see Figure 2As shown, the laser ablation host 1 includes a laser generating mechanism 12, a control module 13, an adjustment module 14, a temperature feedback module 15 and a setting module 16, wherein the laser generating mechanism 12 is used to generate ablation laser; the control module 13 is electrically connected to the laser generating mechanism 12, and is used to control the power of the laser emitted by the laser generating mechanism 12; the adjustment module 14 is electrically connected to the control module 13, and is used to control the power of the laser emitted by the laser generating mechanism 12 through the control module 13; the temperature feedback module 15 is electrically connected to the control module 13, and is used to monitor the temperature of the laser mediation cap 3 and feed back to the control module 13; the setting module 16 is electrically connected to the control module 13 to limit the working temperature of the laser mediation cap 3 and the working time and the emitted laser power of the laser generating mechanism 12.

[0049] The laser ablation host 1 in this embodiment generates laser light by the laser generating mechanism 12, and the generated laser light is transmitted to the optical fiber 2 through the optical fiber connection port 11 on the laser ablation host 1. The laser generation process is a mature technology, and the laser generating mechanism 12 is not further described in detail here, and an existing finished laser generator can be used. It can be understood that the control module 13 in this embodiment can control the laser generating mechanism 12, control the power and time of the laser output by the laser generating mechanism 12, so as to realize the temperature control of the laser mediating cap 3. Specifically, the setting module 16 can be used to set the working temperature of the laser-mediated cap 3 and the working time and the emitted laser power of the laser generating mechanism 12 before the operation. Based on the working time and the emitted laser power of the laser generating mechanism 12 set by the setting module 16, the laser generating mechanism 12 is controlled to work, the laser-mediated cap 3 is heated, the temperature of the laser-mediated cap 3 is monitored in real time, and the temperature feedback module 15 is fed back to the control module 13. When the temperature of the laser-mediated cap 3 is too high, the control module 13 controls the laser generating mechanism 12 to reduce the output power to reduce the heat obtained by the laser-mediated cap 3, to achieve cooling of the laser-mediated cap 3, and to achieve precise control of the temperature of the laser-mediated cap 3. Similarly, during the laser ablation process, the real-time output laser power of the laser generating mechanism 12 can also be adjusted through the adjustment module 14 according to actual needs to better match the laser ablation process.

[0050] In some examples of the laser ablation apparatus of the present invention, see Figure 3As shown, the laser ablation host 1 also includes a housing 17, on which a setting panel 171, an adjustment panel 172 and a display panel 173 are provided, wherein the setting panel 171 is electrically connected to the setting module 16, and is used to set the working temperature of the laser mediation cap 3 and the working time and the laser emission power of the laser generating mechanism 12. The adjustment panel 172 is electrically connected to the adjustment module 14, and is used to adjust the power of the laser emitted by the laser generating mechanism 12. The display panel 173 is electrically connected to the control module 13, and the display panel 173 includes a setting working display area and a real-time working display area, wherein the setting working display area is used to display the set temperature of the laser mediation cap 3, the set working time of the laser generating mechanism 12, and the set power of the laser emitted by the laser generating mechanism 12; the real-time working display area is used to display the real-time temperature of the laser mediation cap 3, the real-time working time of the laser generating mechanism 12, and the real-time power of the laser emitted by the laser generating mechanism 12.

[0051] It can be understood that the laser ablation device in this example, the laser generating mechanism 12, the control module 13, the adjustment module 14, the temperature feedback module 15 and the setting module 16 are all located in the housing 17, and the operation control of the laser ablation host 1 can be realized through the setting panel 171, the adjustment panel 172 and the display panel 173 on the housing 17. Among them, the operation of the setting module 16 can be realized through the setting panel 171, the operation of the adjustment module 14 can be realized through the adjustment panel 172, and the display panel 173 can display the real-time temperature of the laser-mediated cap 3 and the laser ablation time and the laser emission power in real time. Combined with the functions of each module in the above embodiment, the laser ablation host 1 of this embodiment can realize preoperative setting (setting panel 171 and setting module 16), intraoperative monitoring (display panel 173) and intraoperative adjustment (adjustment panel 172 and adjustment module 14), and efficiently realize accurate ablation of tissue.

[0052] In some embodiments of the laser ablation device of the present invention, see Figure 4 As shown, the optical fiber 2 includes an optical fiber core 21 and an optical fiber jacket 22 wrapped around the outer circumference of the optical fiber core 21, the laser mediation cap 3 is connected to the end of the optical fiber jacket 22, and the working end of the optical fiber core 21 extends out of the end of the optical fiber jacket 22 and is located in the laser mediation cap 3.

[0053] It can be understood that the optical fiber core 21 is wrapped with the optical fiber jacket 22. The optical fiber jacket 22 protects the outer reflective film of the optical fiber core 21 from being scratched by external forces and prevents the optical fiber core 21 from breaking. The laser mediation cap 3 is installed at the end of the optical fiber jacket 22. The working end of the optical fiber core 21 extends out of the optical fiber jacket 22 and is sealed in the laser mediation cap 3. The laser mediation cap 3 prevents the working end of the optical fiber core 21 from directly contacting the body tissue, effectively isolates the direct contact between the optical fiber 2 and the body tissue, and ensures the stable transmission of laser power through the optical fiber.

[0054] In some specific examples, the laser-mediated cap 3 is a cylindrical metal cap, which is suitable for receiving the laser output from the working end of the optical fiber 2 and uniformly conducting heat energy on the cylinder. Of course, the structure of the laser-mediated cap 3 is not limited to a cylinder, and a spherical, elliptical, needle-shaped structure can also be adopted. It can be designed, manufactured and installed according to actual needs. The material of the laser-mediated cap 3 is not limited to a metal material, as long as it has a material that can sense temperature and conduct heat quickly. In this example, the laser-mediated cap 3 is a metal cylinder. It can be understood that the laser energy acts on the laser-mediated cap 3. After the laser heats the metal, the heat energy is evenly distributed on the laser-mediated cap 3. The uniform heat energy on the laser-mediated cap 3 performs thermal coagulation and ablation on the lesion tissue. The surface area of ​​the laser-mediated cap 3 can be hundreds of times the cross-sectional area of ​​the optical fiber inner core 21. The uniform heat energy on the surface of the laser-mediated cap 3 is used to perform thermal coagulation and ablation of the lesion tissue, which expands the ablation range and avoids tissue carbonization. It should be understood that the laser-mediated cap 3 can have a variety of sizes, allowing the use of metal caps of different shapes and sizes for replacement, thereby enhancing the applicability and flexibility of the device and making it suitable for the treatment of soft tissue lesions of different types and sizes.

[0055] Furthermore, a plurality of temperature sensors are evenly distributed on the laser-mediated cap 3, and the temperature sensors are used to monitor the real-time temperature of the laser-mediated cap 3. The temperature sensor can be connected to the temperature feedback module 15 of the laser ablation host 1 by wireless connection or wire connection. During the laser ablation process, the temperature of the laser-mediated cap 3 is monitored in real time by the temperature sensor on the laser-mediated cap 3, and the monitoring information is transmitted to the temperature feedback module 15 to guide the doctor to adjust the laser power, avoid tissue carbonization, and efficiently achieve accurate ablation of the tissue.

[0056] After the laser beam provided by the optical fiber 2 acts on the inner wall of the laser-mediated cap 3, it is necessary to make the laser-mediated cap 3 absorb the laser beam energy as much as possible and convert it into its own heat. However, part of the laser beam may be reflected back to the optical fiber 2 through the inner wall of the laser-mediated cap 3, causing damage to the optical fiber 2. Based on this process, in some specific examples, the inner wall of the laser-mediated cap 3 is designed to be a diffuse reflection inner wall. By making a rough inner wall surface or using special processes such as frosting, the inner wall of the laser-mediated cap 3 can form a diffuse reflection. The light beam reflected by the inner wall of the laser-mediated cap 3 will act on other positions of the inner wall of the laser-mediated cap 3 again to the greatest extent, and will not be reflected back to the optical fiber 2. While protecting the optical fiber 2, the absorption and conversion effect of the laser-mediated cap 3 is further enhanced.

[0057] In some embodiments of the laser ablation device of the present invention, see Figure 5 As shown, a beam expander 4 is provided in the laser-mediated cap 3. The beam expander 4 is located at the working end of the optical fiber 2. The beam expander 4 is arranged parallel to the bottom end surface of the laser-mediated cap 3 to expand the laser output from the working end of the optical fiber 2 so that the expanded laser acts on the bottom end surface of the laser-mediated cap 3.

[0058] The beam expander 4 is designed to expand the diameter of the parallel input light beam to a larger parallel output light beam. In this embodiment, the laser output from the working end of the optical fiber 2 passes through the beam expander 4. Figure 5 As shown by the arrow in , the laser beam is expanded into a larger diameter, the coverage of the laser beam is expanded, and the laser energy per unit area is reduced, so that the laser energy can cover the bottom end surface of the laser-mediated cap 3 in a larger range, thereby accelerating the heat diffusion process on the laser-mediated cap 3.

[0059] In other embodiments of the laser ablation device of the present invention, see Figure 6 As shown, a beam splitter 5 is provided in the laser-mediated cap 3 , and the beam splitter 5 is located at the working end of the optical fiber 2 . The beam splitter 5 is used to evenly diverge the laser output from the working end of the optical fiber 2 , so that the diverged laser acts on the inner wall of the laser-mediated cap 3 .

[0060] The beam splitter 5 can split a beam of light into two or more beams of light. The beam splitter 5 can use a metal film or a dielectric film. In this embodiment, the laser output from the working end of the optical fiber 2 passes through the beam splitter 5. Figure 6 As shown by the arrows in , the laser is differentiated from point-like direct radiation into multiple divergent laser beams, which act evenly on the inner wall of the laser-mediated cap 3 and can also accelerate the heat diffusion of the laser energy on the laser-mediated cap 3 .

[0061] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A laser ablation method, characterized in that: include: Acquiring an ablation temperature of the ablation target based on the ablation target; Based on the ablation temperature, controlling the laser ablation host (1) to output laser light, and transmitting the laser light through the optical fiber (2) to act on the laser mediation cap (3), so as to heat the laser mediation cap (3) to the ablation temperature; The laser ablation host (1) is kept outputting laser light, so that the laser mediation cap (3) maintains the ablation temperature, and the laser mediation cap (3) is used to perform laser ablation on the ablation target.

2. The laser ablation method according to claim 1, characterized in that: The step of maintaining the laser ablation host (1) to output laser light so that the laser mediation cap (3) maintains the ablation temperature comprises: Obtaining the real-time temperature of the laser-mediated cap (3); Based on the acquired real-time temperature of the laser-mediated cap (3), the power of the laser output by the laser ablation host (1) is adjusted to reheat the laser-mediated cap (3) to the ablation temperature.

3. The laser ablation method according to claim 1, characterized in that: The step of performing laser ablation on the ablation target using the laser-mediated cap (3) comprises: acquiring an ablation time of the ablation target based on the ablation target; Based on the ablation time, the laser-mediated cap (3) is controlled to perform an ablation operation on the ablation target for the ablation time at the ablation temperature, thereby completing laser ablation of the ablation target.

4. A laser ablation device, characterized in that: Suitable for performing the laser ablation method according to any one of claims 1 to 3, the laser ablation device comprising: A laser ablation main unit (1) for generating laser light, wherein the laser ablation main unit (1) is provided with an optical fiber connection port (11) for outputting laser light; An optical fiber (2) used for transmitting laser light generated by the laser ablation host (1), wherein a first end of the optical fiber (2) is connected to the optical fiber connection port (11); The laser-mediated cap (3) is connected to the second end of the optical fiber (2) and is suitable for outputting laser light through the optical fiber (2) to act on the laser-mediated cap (3) so as to heat the laser-mediated cap (3).

5. The laser ablation device according to claim 4, characterized in that: The laser ablation host (1) comprises: A laser generating mechanism (12) for generating ablative laser; A control module (13), electrically connected to the laser generating mechanism (12), and used to control the power of the laser emitted by the laser generating mechanism (12); A regulating module (14), electrically connected to the control module (13), and used for controlling the power of the laser emitted by the laser generating mechanism (12) through the control module (13); A temperature feedback module (15), electrically connected to the control module (13), and used to monitor the temperature of the laser-mediated cap (3) and provide feedback to the control module (13); A setting module (16) is electrically connected to the control module (13) to limit the operating temperature of the laser-mediated cap (3) and the operating time and emitted laser power of the laser generating mechanism (12).

6. The laser ablation device according to claim 5, characterized in that: The laser ablation host (1) further comprises a housing (17), on which a setting panel (171), an adjustment panel (172) and a display panel (173) are provided; The setting panel (171) is electrically connected to the setting module (16) and is used to set the working temperature of the laser mediation cap (3) and the working time and emitted laser power of the laser generating mechanism (12); The adjustment panel (172) is electrically connected to the adjustment module (14) and is used to adjust the power of the laser emitted by the laser generating mechanism (12); The display panel (173) is electrically connected to the control module (13), and comprises a set working display area and a real-time working display area. The set working display area is used to display the set temperature of the laser mediation cap (3), the set working time of the laser generating mechanism (12), and the set power of the laser emitted by the laser generating mechanism (12); the real-time working display area is used to display the real-time temperature of the laser mediation cap (3), the real-time working time of the laser generating mechanism (12), and the real-time power of the laser emitted by the laser generating mechanism (12).

7. The laser ablation device according to claim 4, characterized in that: The optical fiber (2) comprises an optical fiber inner core (21) and an optical fiber jacket (22) wrapped around the outer circumference of the optical fiber inner core (21); the laser mediation cap (3) is connected to the working end of the optical fiber jacket (22); the working end of the optical fiber inner core (21) extends out of the end of the optical fiber jacket (22) and is located in the laser mediation cap (3).

8. The laser ablation device according to claim 7, characterized in that: A plurality of temperature sensors are evenly distributed on the laser-mediated cap (3), and the temperature sensors are used to monitor the real-time temperature of the laser-mediated cap (3); The inner wall of the laser-mediated cap (3) forms a diffuse reflection inner wall.

9. The laser ablation device according to claim 8, characterized in that: A beam expander (4) is arranged inside the laser-mediated cap (3), and the beam expander (4) is located at the working end of the optical fiber (2). The beam expander (4) is arranged parallel to the bottom end surface of the laser-mediated cap (3) to expand the laser light output from the working end of the optical fiber (2), so that the expanded laser light acts on the bottom end surface of the laser-mediated cap (3).

10. The laser ablation device according to claim 8, characterized in that: A beam splitter (5) is arranged inside the laser-mediated cap (3), and the beam splitter (5) is located at the working end of the optical fiber (2). The beam splitter (5) is used to evenly diverge the laser light output from the working end of the optical fiber (2), so that the diverged laser light acts on the inner wall of the laser-mediated cap (3).

Citation Information

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