A Chinese medicine formula for treating bone erosion and its preparation method

Abstract

The present invention relates to the technical field of Chinese medicine formula, and in particular to a Chinese medicine formula for treating bone erosion and a preparation method thereof. Technical problem: In the process of treating bone erosion, the treatment mechanism of some western medicines is relatively single, which only temporarily relieves the symptoms and cannot fundamentally adjust the overall immune and physical state. Under long-term use, it can be accompanied by more side effects, and it is impossible to fine-tune the prescription ratio according to the patient's condition, physical condition, age and other characteristics to achieve the problem of comprehensive conditioning and recovery. Technical solution: A Chinese medicine formula for treating bone erosion, comprising the following components: Chuanxiong 3g-10g, Su Mu 3g-9g, Sanguisorba officinalis 1g-1.5g, Leech 3g-9g, Deer Horn Glue 6g-12g, Drynariae Rhizoma 10g-20g, Dipsacus asper 6g-15g, Natural Copper 10g-15g, Achyranthes bidentata 5g-15g, Eupolyphaga sinensis 6g, Corydalis 3g-10g, etc. The Chinese medicine formula of the present invention can be used for comprehensive conditioning, and the prescription ratio can be adjusted according to the patient's condition, constitution, age and other characteristics, and can play a fundamental therapeutic effect under long-term treatment.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine formulas, and in particular to a traditional Chinese medicine formula for treating bone erosion and a preparation method thereof. Background Art

[0002] Some of the current drugs used for bone erosion have relatively simple treatment mechanisms, which only temporarily relieve symptoms and cannot fundamentally regulate the overall immune and physical state. Long-term use may be accompanied by more side effects, such as indigestion, immunosuppression, etc., and may also affect liver and kidney function. For long-term use of antibiotics and immunosuppressants, the efficacy will decrease due to drug resistance. The Chinese medicine formulas for bone erosion used on the market have relatively simple efficacy, and it is impossible to fine-tune the prescription ratio according to the patient's condition, physical condition, age and other characteristics to achieve individualized treatment. Therefore, it is urgently needed to set up a Chinese medicine formula that can effectively treat bone erosion, which can perform comprehensive conditioning, improve the overall physical condition and immune function, help overall recovery and regulation, have fewer side effects, and generally will not have much impact on liver and kidney function during medication. It pays more attention to long-term effects and fundamental treatment, which can not only relieve symptoms, but also promote the body's self-repair ability. Summary of the invention

[0003] In order to overcome the problem that in the process of treating bone erosion, some Western medicines have relatively single treatment mechanisms, which only temporarily relieve symptoms and cannot fundamentally regulate the overall immune and physical state. Long-term use may be accompanied by more side effects, such as digestive tract discomfort, immunosuppression, etc. It is impossible to fine-tune the prescription ratio according to the patient's condition, physical condition, age and other characteristics to achieve comprehensive conditioning and recovery.

[0004] The technical scheme of the present invention is: a traditional Chinese medicine formula for treating bone erosion, comprising the following components: 3g-10g of Chuanxiong, 3g-9g of Sappan wood, 1g-1.5g of Sanguisorba officinalis, 3g-9g of Leech, 6g-12g of Deer Horn Glue, 10g-20g of Drynaria Rhizoma, 6g-15g of Dipsacus asper, 10g-15g of Natural Copper, 5g-15g of Achyranthes bidentata, 6g of Eupolyphaga sinensis, 3g-10g of Corydalis yanhusuo, 10g-15g of Ganoderma lucidum and 10g of Patchouli.

[0005] Preferably, the mass ratio of Chuanxiong, Sappan wood and Corydalis is 1:1:1.

[0006] As a preferred method, the main rhizome of Chuanxiong should be fresh, insect-free, and well-dried. After washing and drying, the Chuanxiong should be cut into small pieces for later use.

[0007] Preferably, the Sanguisorba officinalis is of full texture and bright color. Both the root and the whole plant of Sanguisorba officinalis can be used as medicine. After washing, cut into small pieces or chop, dry and set aside.

[0008] Preferably, the leeches are plump, intact, and bright red in color.

[0009] Preferably, the Drynaria used is hard, insect-free and mildew-free. The Drynaria is washed, dried and cut into small pieces for later use.

[0010] Preferably, the whole plant or the above-ground part of the Dipsacus asper is used, and fresh and tender Dipsacus asper without disease and insect pests is selected. The Dipsacus asper is washed and then dried. The whole plant can be dried or chopped for later use.

[0011] A method for preparing a traditional Chinese medicine formula for treating bone erosion, comprising the traditional Chinese medicine formula for treating bone erosion as described above, and the steps are as follows: Step 1: Prepare the ingredients Prepare 3g-10g of Chuanxiong, 3g-9g of Su Mu, 1g-1.5g of Sanguisorba officinalis, 3g-9g of Hirudo, 6g-12g of Deer Horn Glue, 10g-20g of Drynaria, 6g-15g of Dipsacus asper, 10g-15g of Natural Copper, 5g-15g of Achyranthes bidentata, 6g of Eupolyphaga sinensis, 3g-10g of Corydalis yanhusuo, 10g-15g of Ganoderma lucidum, and 10g of Patchouli, for a total of 13 doses. Step 2: First Decoction Preparation Put the above Chinese medicinal materials into a ceramic container, add water and soak for half an hour, boil over high heat and then simmer for 12-30 minutes until the medicinal juice presents a rich color and aroma, and pour out the first decoction; Step 3: Second Decoction Preparation Add cold boiled water or warm water to the ceramic container in step 2 again, and continue to soak the newly cooked residue until the water just soaks the residue. Simmer on low heat for 5-10 minutes after the water boils. Pour out the second decoction, mix the two decoctions together, and take it warm twice a day, morning and evening, one dose per day.

[0012] Preferably, the first decoction prepared in step 2 can be filtered out through a clean filter or cloth.

[0013] The beneficial effects of the present invention are as follows: the use of Chuanxiong in the formula can invigorate blood circulation and dissipate blood stasis, promote qi circulation and relieve pain. In the treatment of bone erosion, it is helpful to promote blood circulation and relieve pain. Su Mu has the effects of reducing swelling, dispersing nodules, invigorating blood circulation and relieving pain, helps to reduce local inflammation and swelling, and promotes the repair of damaged tissues. The main effects of Xue Jie are cooling blood and stopping bleeding, invigorating blood circulation and removing blood stasis. In the treatment of bone erosion, it is helpful to improve blood circulation, reduce bleeding and promote wound healing. Leech has obvious effects of reducing swelling, invigorating blood circulation and removing blood stasis. It can help clear blood stasis and improve local blood circulation, and is helpful to treat local pain and edema caused by bone erosion. Drynaria is a nourishing medicinal material that helps to strengthen muscles and bones and promote bone growth. In the treatment of bone erosion, it can enhance the nutritional supply and repair ability of bones. Dipsacus has the effects of invigorating blood circulation and dissipating blood stasis, dispelling wind and relieving pain, and can improve local blood circulation, relieve pain, and promote tissue repair and regeneration. Natural copper is mainly used for It can promote blood circulation, remove blood stasis, clear away heat and detoxify. In the treatment of bone erosion, it helps to eliminate inflammation, promote wound healing, and relieve local pain. Chinese Achyranthes bidentata has the effects of strengthening tendons and bones, promoting blood circulation and relieving pain. It can help enhance joint stability and flexibility and reduce joint pain during treatment. Earthworm can improve local blood circulation, relieve pain, and promote tissue repair: Yuanhu can improve blood circulation around joints, relieve inflammation and pain. Ganoderma lucidum has the effects of regulating immune function, anti-inflammatory and antioxidant. In the treatment of bone erosion, it helps to enhance the body's immunity and promote tissue repair and regeneration. Patchouli has the effects of relieving exterior symptoms, dispersing cold, removing dampness and relieving pain. In the treatment of bone erosion, it helps to improve local dampness symptoms and relieve joint pain and discomfort. This Chinese medicine formula can be used for comprehensive conditioning, and the prescription ratio can be adjusted according to the patient's condition, constitution, age and other characteristics. It can play a fundamental therapeutic effect under long-term treatment. DETAILED DESCRIPTION

[0014] Example 1 The present invention will be further described below in conjunction with the embodiments.

[0015] The present invention provides an embodiment: a traditional Chinese medicine formula for treating bone erosion, comprising the following components: 3g of Chuanxiong, 3g of Su Mu, 1g of Sanguisorba officinalis, 3g of Hirudo, 6g of Deer Horn Glue, 10g of Drynaria Rhizoma, 6g of Dipsacus asper, 10g of Natural Copper, 5g of Achyranthes bidentata, 6g of Eupolyphaga sinensis, 3g of Corydalis yanhusuo, 10g of Ganoderma lucidum, and 10g of Patchouli, wherein the mass ratio of Chuanxiong, Su Mu and Corydalis yanhusuo is 1:1:1, and the main rhizome part of Chuanxiong that is fresh, free of insect infestation and well dried should be used, and Chuanxiong should be washed, dried and cut into Small pieces are set aside. For the Sanguisorba officinalis, use the ones with full texture and bright color. Either the root or the whole plant can be used as medicine. Wash it, cut it into small pieces or chop it up, dry it and set aside. For the leeches, use the ones with full texture, no damage and bright red color. For the Drynaria, use the ones with hard texture, no insect infestation and no mildew. Wash it, dry it, cut it into small pieces and set aside. For the Dipsacus asper, mainly use its whole plant or the above-ground part. Choose the fresh and tender Dipsacus asper without disease and insect pests. Wash it and dry it. You can dry it whole or chop it up and set aside.

[0016] A method for preparing a traditional Chinese medicine formula for treating bone erosion, comprising the traditional Chinese medicine formula for treating bone erosion as described above, and the steps are as follows: Step 1: Prepare the ingredients Prepare 3g of Chuanxiong, 3g of Su Mu, 1g of Sanguisorba officinalis, 3g of Hirudo, 6g of Deer Horn Glue, 10g of Drynariae, 6g of Dipsacus asper, 10g of Natural Copper, 5g of Achyranthes bidentata, 6g of Eupolyphaga sinensis, 3g of Corydalis yanhusuo, 10g of Ganoderma lucidum, and 10g of Patchouli, for a total of 12 doses. Step 2: First Decoction Preparation Put the above Chinese medicinal materials into a ceramic container, add water and soak for half an hour, boil over high heat and then simmer for 20-30 minutes until the juice shows a rich color and aroma, pour out the first decoction, and filter the first decoction through a clean filter or cloth; Step 3: Second Decoction Preparation Add cold boiled water or warm water to the ceramic container in step 2 again, and continue to soak the newly cooked residue until the water just soaks the residue. Simmer on low heat for 5-10 minutes after the water boils. Pour out the second decoction, mix the two decoctions together, and take it warm twice a day, morning and evening, one dose per day.

[0017] Example 2 The present invention will be further described below in conjunction with the embodiments.

[0018] The invention provides an embodiment: a traditional Chinese medicine formula for treating bone erosion, comprising the following components: 5g of Chuanxiong, 5g of Sappan wood, 1g of Dragon's Blood, 4g of Hirudo, 8g of Deer Horn Glue, 15g of Drynaria Rhizoma, 10g of Dipsacus asper, 12g of Natural Copper, 13g of Achyranthes bidentata, 6g of Eupolyphaga sinensis, 5g of Corydalis yanhusuo, 12g of Ganoderma lucidum, and 10g of Patchouli, wherein the mass ratio of Chuanxiong, Sappan wood and Corydalis yanhusuo is 1:1:1, and the main rhizome part of Chuanxiong that is fresh, free of insect infestation and well dried should be used, and the Chuanxiong should be washed and dried, cut into Cut into small pieces for later use. For the Dragon's Blood, use the ones with full texture and bright color. The root or the whole plant of Dragon's Blood can be used as medicine. Wash it, cut it into small pieces or chop it, dry it and set it aside. For the leech, use the ones with full texture, no damage and bright red color. For the Drynaria, use the ones with hard texture, no insect infestation and no mildew. Wash it, dry it, cut it into small pieces for later use. For the Dipsacus, mainly use its whole plant or the above-ground part. Choose the fresh and tender Dipsacus without disease and insect pests. Wash it and dry it. You can dry it whole or chop it for later use.

[0019] A method for preparing a traditional Chinese medicine formula for treating bone erosion, comprising the traditional Chinese medicine formula for treating bone erosion as described above, and the steps are as follows: Step 1: Prepare the ingredients Prepare 5g of Chuanxiong, 5g of Su Mu, 1g of Sanguisorba officinalis, 4g of Hirudo, 8g of Deer Horn Glue, 15g of Drynariae, 10g of Dipsacus asper, 12g of Natural Copper, 13g of Achyranthes bidentata, 6g of Eupolyphaga, 5g of Corydalis, 12g of Ganoderma lucidum, and 10g of Patchouli, for a total of 12 doses. Step 2: First Decoction Preparation Put the above Chinese medicinal materials into a ceramic container, add water and soak for half an hour, boil over high heat and then simmer for 20-30 minutes until the juice shows a rich color and aroma, pour out the first decoction, and filter the first decoction through a clean filter or cloth; Step 3: Second Decoction Preparation Add cold boiled water or warm water to the ceramic container in step 2 again, and continue to soak the newly cooked residue until the water just soaks the residue. Simmer on low heat for 5-10 minutes after the water boils. Pour out the second decoction, mix the two decoctions together, and take it warm twice a day, morning and evening, one dose per day.

[0020] Example 3 The present invention will be further described below in conjunction with the embodiments.

[0021] The present invention provides an embodiment: a traditional Chinese medicine formula for treating bone erosion, comprising the following components: a traditional Chinese medicine formula for treating bone erosion, comprising the following components: 10g of Chuanxiong, 9g of Su Mu, 1.5g of Sanguisorba officinalis, 9g of Leech, 12g of Deer Horn Glue, 12g of Drynariae Rhizoma, 12g of Dipsacus asper, 15g of Natural Copper, 8g of Achyranthes bidentata, 6g of Eupolyphaga sinensis, 10g of Corydalis yanhusuo, 15g of Ganoderma lucidum, and 10g of Patchouli, the mass ratio of Chuanxiong, Su Mu and Corydalis yanhusuo is 1:1:1, and the main rhizome of Chuanxiong should be fresh, insect-free and well-dried For the leech, use the leech with a full texture, no damage and bright red color. Use the Drynaria fortunei that has a hard texture, no insects or mildew. Wash the Drynaria fortunei, dry it, cut it into small pieces for later use. The whole plant or the above-ground part of the Dipsacus asper is mainly used. Choose the fresh and tender Dipsacus fortunei that is free of diseases and insect pests. Wash the Dipsacus fortunei and dry it. It can be dried as a whole plant or chopped for later use.

[0022] A method for preparing a traditional Chinese medicine formula for treating bone erosion, comprising the traditional Chinese medicine formula for treating bone erosion as described above, and the steps are as follows: Step 1: Prepare the ingredients Prepare 10g of Chuanxiong, 9g of Su Mu, 1.5g of Sanguisorba officinalis, 9g of Hirudo, 12g of Deer Horn Glue, 12g of Drynariae, 12g of Dipsacus asper, 15g of Natural Copper, 8g of Achyranthes bidentata, 6g of Eupolyphaga sinensis, 10g of Corydalis, 15g of Ganoderma lucidum, and 10g of Patchouli, for a total of 12 doses. Step 2: First Decoction Preparation Put the above Chinese medicinal materials into a ceramic container, add water and soak for half an hour, boil over high heat and then simmer for 12-30 minutes, until the juice presents a rich color and aroma, pour out the first decoction, and filter the first decoction through a clean filter or cloth; Step 3: Second Decoction Preparation Add cold boiled water or warm water to the ceramic container in step 2 again, and continue to soak the newly cooked residue until the water just soaks the residue. Simmer on low heat for 5-10 minutes after the water boils. Pour out the second decoction, mix the two decoctions together, and take it warm twice a day, morning and evening, one dose per day.

[0023] Example 4 The present invention will be further described below in conjunction with the embodiments.

[0024] The invention provides an embodiment: a traditional Chinese medicine formula for treating bone erosion, comprising the following components: 8g of Chuanxiong, 4g of Sappan wood, 1.2g of Dragon's Blood, 4g of Hirudo, 10g of Deer Horn Glue, 16g of Drynariae Rhizoma, 9g of Dipsacus asper, 12g of Natural Copper, 11g of Achyranthes bidentata, 6g of Eupolyphaga sinensis, 7g of Corydalis yanhusuo, 12g of Ganoderma lucidum, and 10g of Patchouli, wherein the mass ratio of Chuanxiong, Sappan wood and Corydalis yanhusuo is 1:1:1, and the Chuanxiong should be a fresh, insect-free, well-dried main rhizome part, and the Chuanxiong should be washed and air-dried. Cut into small pieces for later use. For the Dragon's Blood, use the ones with full texture and bright color. Either the root or the whole plant of the Dragon's Blood can be used as medicine. Wash it, cut it into small pieces or chop it up, dry it and set it aside. For the leech, use the ones with full texture, no damage and bright red color. For the Drynaria, use the ones with hard texture, no insect infestation and no mildew. Wash it, dry it, cut it into small pieces for later use. For the Dipsacus, mainly use its whole plant or the above-ground part. Choose the fresh and tender Dipsacus without disease and insect pests. Wash it and dry it. You can dry it whole or chop it up for later use.

[0025] A method for preparing a traditional Chinese medicine formula for treating bone erosion, comprising the traditional Chinese medicine formula for treating bone erosion as described above, and the steps are as follows: Step 1: Prepare the ingredients Prepare 8g of Chuanxiong, 4g of Su Mu, 1.2g of Sanguisorba officinalis, 4g of Hirudo, 10g of Deer Horn Glue, 16g of Drynariae, 9g of Dipsacus asper, 12g of Natural Copper, 11g of Achyranthes bidentata, 6g of Eupolyphaga, 7g of Corydalis, 12g of Ganoderma Lucidum, and 10g of Patchouli, for a total of 12 doses. Step 2: First Decoction Preparation Put the above Chinese medicinal materials into a ceramic container, add water and soak for half an hour, boil over high heat and then simmer for 20-30 minutes until the juice shows a rich color and aroma, pour out the first decoction, and filter the first decoction through a clean filter or cloth; Step 3: Second Decoction Preparation Add cold boiled water or warm water to the ceramic container in step 2 again, and continue to soak the newly cooked residue until the water just soaks the residue. Simmer on low heat for 5-10 minutes after the water boils. Pour out the second decoction, mix the two decoctions together, and take it warm twice a day, morning and evening, one dose per day.

[0026] Experimental Example 1 Huang, male, 66 years old, was unfortunately infected during the SARS period in 2003. The hospital used hormones to treat the lungs, which caused dull pain in the joints of both legs, which was continuous, stiff joints, irritability, thirst, insomnia, and dry throat. He was introduced to my clinic for treatment by others. The laboratory 4-word examination of the hip joints of both lower limbs was positive. He walked with difficulty and had facial pain. The CT scan showed that the left hip bone erosion was stage III and the right hip bone was stage II: Chinese medicine diagnosed it as bone erosion (kidney deficiency and blood stasis syndrome). The Chinese medicine formula of Example 1 was used for taking. The diet avoided spicy food, cold, alcohol, garlic, star anise, pepper, mutton, and blood nourishment. It was forbidden to walk with weight, use crutches, prevent bone "fatigue", and prevent collapse. At the same time, Musk Blood Activating and Pain Relief Paste plus three-point three-point powder was applied to the affected area for pain relief; The patient was re-examined 15 days later. The medicine and the symptoms were consistent. After taking the above prescription, the pain of bone erosion in both hips was relieved (applied externally). The prescription was continued without change, but the dosage was increased to nourish the liver and kidneys, 15 grams of Achyranthes bidentata and 15 grams of Dipsacus asper, 28 doses, and the diet and care were the same as above. The patient was re-examined 29 days later. After taking the above prescription, the 4th, 5th and 6th visits were the same as above, and the trabeculae showed signs of contour. The patient was changed to oral administration of Huogu Pills, 20-30 grams three times a day, to increase the repair of bone erosion in the colloid layer of the ball cartilage. The "Huogu Pills or Powder" were taken for 5 months in a row, and the patient was able to walk normally and was cured. Experimental Example 2 Mr. Ma, male, 45 years old, had right hip pain without obvious cause half a year ago, the pain in hip joint became more severe when squatting, he bought rheumatism ointment for external use in the pharmacy, but the effect was not good, he was treated in the hospital the year before last, MRI showed: snake-like low signal in the right femoral head, obvious edema signal in the right hip joint, diagnosed with right femoral head necrosis (CTII), came to our clinic for treatment, current symptoms: right hip joint pain, obvious tenderness in the right groin, limited abduction and adduction of right lower limb, positive 4-word test: Dialectical analysis: the patient usually likes to drink and eat excessively, and wine is a damp and hot product. Drinking for a long time will gather dampness and generate heat, and the heat evil will burn the body fluids. The dampness evil will be sticky and difficult to transform, and the dampness and heat will be intertwined and gathered in the tendons and bones. The evil qi will gather, and its qi must be weak. The dampness and heat will gather in the femur, hindering the circulation of qi and blood, qi stagnation and blood stasis, and the hip bone will be malnourished, forming bone erosion: Chinese medicine diagnosed it as bone erosion (phlegm and blood stasis syndrome), and Western medicine diagnosed it as alcoholic femoral head necrosis. The Chinese medicine formula of Example 2 was taken, and spicy food, wind and cold, alcohol, garlic, star anise, pepper, mutton, and blood were prohibited. It was forbidden to walk with weight, and crutches were used to prevent bone "fatigue" and collapse. At the same time, Musk Blood Activating and Analgesic Ointment plus three fen and three powder were applied to the affected area to relieve pain; After a follow-up visit 15 days later, the medicine and the syndrome were in harmony, the pain was relieved, the right groin pressure and teeth turned, and the yellow greasy fur gradually disappeared. The effect did not change the prescription, and the original prescription was continued for 28 doses; The patient was re-examined 29 days later. The pain in the right hip joint had stopped, and no trabecular bone erosion was observed. The dosage of the prescription remained unchanged, and the patient continued to take the "Ancestral Bone-Growing Blood Pain-Relieving Soup" and the diet adjustment was the same as above; The patient was re-examined one month later. There was still no outline of trabecular bone erosion, so the "Ancestral Bone-Growing Blood Pain-Relieving Soup" was continued for 28 doses; The trabecular bone erosion showed improvement at the fifth, sixth, seventh, eighth, and ninth visits, so the patient was changed to oral "Ancestral Bone-Activating Pills or Powder". After 9 months, the cartilage gelatinous layer healed, and the patient completely improved. He no longer had to take crutches, and could walk normally, and there has been no recurrence since then. Experimental Example 3 Shen, male, 67 years old, found left hip pain one and a half years after the car accident. Half a year later, right hip also began to hurt. The pain was more severe at night, the stabbing pain did not move, the joint flexion and extension were not good, the 4-word test of the left and right lower limbs was positive, the tenderness between the left groin was obvious, (CT scan), the left hip ball head joint bone erosion diameter was 13 grams and millimeters long, 12 grams and millimeters deep round hole bone erosion, the degree has reached the left hip III (stage 3) right hip joint is stage II bone erosion: Dialectical analysis:, the patient was injured by external force, the meridians were blocked, the blood circulation was not smooth, the meridians were blocked, and bone erosion was formed: Traditional Chinese medicine diagnosed it as bone erosion (Qi stagnation and blood stasis syndrome), the Chinese medicine formula of Example 3 was used for taking, the diet avoided spicy food, avoid wind and cold, prohibit alcohol, prohibit garlic, star anise pepper, mutton, nourish blood, prohibit weight-bearing walking, crutches, prevent bone "fatigue", prevent collapse, and apply Musk Blood Activating and Pain Relief Paste with three points and three powder to the affected area for pain relief; The patient was re-examined 15 days later. The medicine and the indication were suitable. After taking the above prescription, the right hip joint showed improvement in stage II, and the pain was relieved. If it was not effective, the prescription was increased with a larger dosage of 15 grams of Drynaria fortunei, 15 grams of Dipsacus asper, and 12 grams of Rhizoma Achyranthis Bidentatae. The original prescription was continued for 28 doses, and the diet and care were the same as above. The patient was re-examined 29 days later. After taking the above prescription, the pain in the left and right hip joints improved significantly. The above prescription was continued for 30 doses, and the previous dosage and diet and care were the same as before. After observing the efficacy, the compound prescription was the same as above for 28 doses each at the 4th, 5th, 6th, 7th, 8th and 9th visits. When the trabeculae showed contours, the patient was changed to oral "Huogu Pills or Powder" after 16 times for about 9 months to increase the healing of bone erosion in the colloid layer of the ball cartilage. He could walk 5-8 miles normally without pain or congestion, and worked until retirement.

[0027] Experimental Example 4 Qiao, female, 56 years old, fell to the ground half a year ago because she did not get off her bicycle properly. Since then, she has always felt discomfort in her right hip joint, and her knee joints are sometimes loose and weak. She also has soreness in her hip joints, which is sometimes light and sometimes heavy. She also feels pain when going up and down stairs. As time went by, she felt that the pain in her right hip joint became more and more severe, and the joint had difficulty flexing and extending. CT scan showed that her right hip (bone erosion) was stage II.

[0028] Dialectical analysis: The patient should have suffered from injuries caused by falls, which resulted in damage to the meridians, poor blood circulation, blocked meridians, blood stasis, and bone erosion; Chinese medicine diagnosed the patient as bone erosion (Qi stagnation and blood stasis syndrome), and the Chinese medicine formula of Example 4 was taken, and the patient avoided spicy food, cold, alcohol, weight-bearing walking, and crutches to prevent bone "fatigue" and collapse. At the same time, musk blood-activating and analgesic ointment was applied externally with three-tenths and three-tenths of powder, and aconite powder was applied externally to the affected area to relieve pain; After a follow-up visit on 15 days, the patient's symptoms were consistent, and the pain in the right hip joint was relieved after taking the above prescription, and the continuation prescription was unchanged, and 14 doses of the original prescription were added; Dietary care is the same as above; After another 15 days, the patient will be re-examined. The medicine and the symptoms should be consistent. The same prescription will be continued for 28 doses. Later, the patient will be re-examined once a month. The fourth, fifth and sixth visits are the same as above. The trabeculae showed contours, and the patient started taking bone-activating pills or powder orally, three times a day, 20-30 grams each time, to increase the healing of bone erosion in the ball head of the cartilage gelatinous layer. After taking the "bone-activating pills" for 5 months, everything was back to normal, there was no pain, and the patient was cured.

[0029] Experimental Example 45 Wang Lu, male and female, 74-52 years old, had sudden low back pain while exercising a year ago, involving pain in the right lower limb. CT scan at the local hospital showed: L4 / 5, L5 / S1 intervertebral disc herniation. Conservative treatment with acupuncture and massage relieved the low back pain. One month later, the low back pain recurred after catching a cold, accompanied by right hip joint pain. Acupuncture and massage were used in the clinic to treat the low back pain, but the hip joint pain was not significantly relieved, so he went to the hospital for further examination and was diagnosed with femoral head necrosis and bone erosion II. He was treated with Chinese medicine in the Department of Traditional Chinese Medicine, but the effect was not good, so he came to our clinic for treatment. Current symptoms: right hip joint pain, limited abduction and adduction activities, aggravated pain when standing up and squatting, positive 4-word test in the right lower limb, obvious tenderness in the right groin, and past history: history of trauma.

[0030] Laboratory examination: CT: L4 / 5, L5 / S1 intervertebral disc herniation.

[0031] Dialectical analysis: The patient is old and weak, with liver and kidney deficiency. Liver deficiency leads to weak tendons, kidney deficiency leads to emptiness, and emptiness leads to soft bones. Liver and kidney deficiency leads to weak tendons and bones, which is a sign of qi deficiency and blood stasis. Blood stasis blocks the collaterals, the collaterals are blocked, the tendons and bones are not nourished, exercise is uncomfortable, long-term walking hurts the tendons, standing hurts the bones, liver and kidney are damaged, and blood stasis blocks the collaterals, hip bones are not nourished, and bone erosion is formed. The patient accidentally fell six months ago and sprained and hurt his left ankle joint. However, six months later, his left hip joint was still painful. He felt that there was nothing wrong with him, so he bought injury tablets and Panax notoginseng injury tablets in the pharmacy. The pain in the left ankle joint improved, and the pain in the left hip joint was sometimes light and sometimes heavy. Later, a CT scan in the hospital showed: necrosis of the left femoral head. The patient did not want bone grafting surgery, so he came to our hospital for treatment. The current symptoms: pain in the left hip joint, limited abduction and adduction activities, limping when walking, and positive 4-character test of the left lower limb; Dialectical analysis shows that the patient usually drinks alcohol, which is a damp-heat evil. Dampness consumes the body's positive energy, restrains the spleen, and the qi cannot be distributed throughout the body. Heat burns the body's yin fluid, which leads to the deficiency of essence and kidney deficiency. Blood stasis is formed due to injuries from falls. Blood stasis blocks the collaterals, which blocks the collaterals, causing poor blood circulation and malnutrition of the bone marrow, resulting in bone erosion: Chinese medicine diagnoses the patient as bone erosion (Qi stagnation and blood stasis syndrome). The Chinese medicine formula of Example 1 is used for taking. Spicy and hot foods, ginger, garlic, fish, pepper, star anise, pepper, mutton and sheep blood are avoided in the diet. Alcohol and weight-bearing walking are prohibited. Crutches are used to prevent bone "fatigue" and collapse.

[0032] Fifteen days later, the patient was re-examined. The medicine and symptoms were consistent. The pain in the right hip joint improved, but the patient still complained of pain when squatting. The original prescription was continued for 28 doses, with the decoction method and diet adjustment as before. The patient came for a follow-up visit 30 days later, and then changed to once a month. The symptoms were alleviated and the prescription was not changed. The original prescription was continued for 28 doses, with the decoction method and diet adjustment as before. The fourth, fifth, and sixth visits were the same as above.

[0033] Efficacy observation: stop decoction, change to oral ancestral "bone-activating pill or powder", three times a day, each time 20-30 grams, continue to take for five months, everything is normal, recovery Chinese medicine diagnosis is bone erosion (phlegm and blood stasis syndrome), Western medicine diagnosis alcoholic femoral head necrosis, adopt the Chinese medicine formula of embodiment 4 to take, diet avoid spicy, avoid wind and cold, prohibit alcohol, prohibit garlic, star anise pepper, mutton, nourish blood, prohibit weight-bearing walking, crutches, prevent bone "fatigue", prevent collapse, and apply musk blood-activating analgesic ointment plus three points three powder to the affected area for pain relief; 15 days later, the medicine syndrome should be combined with pain relief, right hip joint pain relief, effect is not changed, the original prescription is continued. 30 doses, the decoction method and diet adjustment are the same as before; Follow-up visit 30 days later, and then follow-up visit once a month. After taking the above prescription, the pain in the right hip joint was significantly relieved, and the damp-heat and blood stasis gradually disappeared, so the dosage of Patchouli was reduced by 9 grams, and the original prescription was continued; 28 doses, fourth, fifth, sixth, seventh, eighth, and ninth visits, the decoction method and diet adjustment are the same as before: Observation of efficacy: Stop taking the decoction, and take Huogu Pills or powder orally three times a day, 20-30 grams each time. After taking the "Huogu Pills" for about a year, there is no pain, no lameness, and everything is normal. He is cured.

[0034] Experimental Example 6 Liang, male, 62 years old, had right hip pain and limited mobility without obvious cause half a year ago. The pain in the hip joint became more severe when he stood up and squatted. He bought rheumatism ointment for external use at the pharmacy, but the effect was not good. He went to the hospital for diagnosis and treatment. The MRI showed: snake-like low signal in the right femoral head and obvious edema signal in the right hip joint. He was diagnosed with right femoral head necrosis (CT Ш). He came to our hospital for diagnosis and treatment. His current symptoms: right joint pain, obvious tenderness in the right groin, limited abduction and adduction of the right lower limb, and the 4-word test was positive.

[0035] Laboratory examination: (CT Ш) bone erosion.

[0036] Past medical history: history of alcoholism for 12 years, drinking an average of half a catty to one catty of liquor a day.

[0037] Dialectical analysis: The patient is addicted to alcohol and excessive eating. Alcohol is a damp-heat product. Drinking for a long time will gather dampness and generate heat, and the heat evil will burn the body fluids. The dampness evil is sticky and difficult to transform. The dampness and heat are intertwined and gathered in the tendons and bones. The evil qi gathers, and the qi must be weak. The dampness and heat gather in the femur, hindering the circulation of qi and blood, qi stagnation and blood stasis, and the hip bone is malnourished, forming bone erosion; Chinese medicine diagnosis is bone erosion (phlegm and blood stasis syndrome), and the Chinese medicine formula of Example 2 is taken, and the diet avoids spicy food, avoids wind and cold, prohibits alcohol, prohibits garlic, star anise, pepper, mutton, nourishes blood, prohibits weight-bearing walking with crutches, prevents bone "fatigue", and prevents collapse. At the same time, Musk Blood Activating and Pain Relief Paste with three-point three-point powder is applied to the affected area to relieve pain; After 15 days of follow-up, the medicine and symptoms were consistent, the pain was relieved, and the tenderness in the right groin improved. The original prescription was continued for 28 doses, and the diet and care were the same as above. The patient was re-examined 29 days later. After taking the above prescription, the pain in the right hip joint was significantly relieved, and the damp-heat evil had been eliminated. Therefore, the incense was reduced and liver and kidney nourishing products were added to strengthen the body. The prescription is as follows: 28 doses of Dipsacus asper and Achyranthes bidentata, the decoction method and diet adjustment are the same as before, and the diet adjustment for the fourth, fifth, and sixth visits is the same as above.

[0038] Observation of therapeutic effect: trabecular bones showed outlines, and the patient changed to taking the family-inherited bone-activating pills or powder. He recovered in six months and could walk normally. Doctor's advice: no alcohol and no weight bearing.

[0039] Experimental Example 7 Mr. Li, male, 68 years old, loves high-intensity exercises such as somersaults, and he also loves going upstairs with weights. Half a year ago, he developed right hip pain without obvious cause, and his joint flexion and extension were difficult. The pain worsened over time. Although the patient had acupuncture and massage in a large hospital, the effect was not good. His abduction and introversion activities have been limited, and he suffers pain when squatting.

[0040] Test examination: The 4-digit test of the left hip joint was positive, and the CT scanning showed that the ball head of the right hip joint was grade II bone erosion.

[0041] Dialectical analysis: The patient suffered from traumatic injuries, blocked meridians, poor blood circulation, and blood stasis, which led to bone erosion. TCM diagnosis was bone erosion (Qi stagnation and blood stasis syndrome). Diet adjustment: avoid spicy food, cold, alcohol, garlic, star anise, pepper, mutton, nourish blood, avoid weight-bearing and walking with crutches, prevent bone "fatigue" and collapse; After 15 days of follow-up, the medicine and the symptoms were consistent. After taking the above prescription and applying it externally, the left hip joint improved and the pain was relieved. The patient came for a follow-up visit 15 days later. After taking the above prescription, the pain in the left hip joint improved significantly. He continued to take the above prescription for 30 doses, with the same dosage and diet as before. After observing the efficacy, he changed to oral administration of the ancestral bone-activating pills or powder to increase the healing of bone erosion in the colloid layer of the ball head cartilage. After 10 months of treatment, he came to us to thank us without crutches. He was cured and could move normally.

[0042] Experimental Example 8 Zhang, female, 60 years old, had low back pain, right hip pain, and right joint pain without obvious cause a year ago, which worsened when going up and down stairs. She went to the hospital for a CT scan, which showed: L3 / L4, L5 / S1 disc herniation, and right femoral head necrosis. After acupuncture and massage treatment, her low back pain improved, but the pain in her right hip joint was not significantly relieved. After hearing the introduction of her friend, she came to my clinic for treatment. Her current symptoms are: obesity, red face, pain in her right hip joint, positive right lower limb 4-word test, limited abduction and adduction of her right lower limb, and pain in the right groin.

[0043] Laboratory examination: CT showed: L3 / 4, L5 / S1 intervertebral disc herniation, right femoral head necrosis, and stage Ш bone erosion.

[0044] Dialectical analysis: The patient is obese, which is a phlegm-damp body. Eating too much fat and greasy food will cause dampness to accumulate and generate heat. The internal dampness and heat will damage the spleen and stomach, and the water and dampness will be transported and transformed improperly, which will aggravate the phlegm and dampness. When the phlegm and heat are exposed, the face will turn red. When the phlegm and heat are intertwined and blocked in the blood vessels, the bone marrow will be deprived of nutrition, causing hip pain and limited movement, resulting in bone erosion. Chinese medicine diagnosis is bone erosion (Qi stagnation and blood stasis syndrome). Diet adjustment: Diet adjustment, avoid spicy and hot foods, ginger, garlic, fish, chili, star anise, pepper, mutton and sheep blood, abstain from alcohol and weight-bearing walking, use crutches to prevent bone "fatigue" and collapse; After 15 days of follow-up, the medicine and symptoms were consistent. The right groin tenderness was relieved, the right hip joint pain was relieved, and the dampness and heat gradually disappeared. There was no need to change the prescription. The original prescription was continued, and the diet and care were the same as before for 28 doses. The decoction method and diet and care were the same as before. The patient was re-examined 29 days later. After taking the above prescription, the pain in the right hip joint was significantly relieved, the tongue coating was thin and white, and the damp-heat evil was gradually eliminated. The dosage of Huangbo, a heat-clearing and dampness-removing medicine, was reduced and added. The patient continued to take 28 doses.

[0045] Efficacy observation: Stop taking decoction and take Huogu Pills orally, three times a day, 20g-30g each time. Change the follow-up visit to once a month; Doctor's instructions: no drinking, no weight-bearing walking, use crutches, prevent bone "fatigue", prevent collapse, avoid mutton and sheep blood, the fourth, fifth, sixth, seventh, eighth, and ninth visits are the same as above. The trabeculae were found to have a spherical head outline, so the patient was cured by taking "ancestral bone-activating pills or powder" orally. The patient had bone erosion in the gelatinous layer of the cartilage. After fourteen months of oral administration of bone-activating pills or powder, the patient put down his crutches and has not had a relapse since then, and is cured.

Claims

1. A Chinese medicine formula for treating bone erosion, characterized in that: It includes the following components: 3g-10g of Chuanxiong, 3g-9g of Sappan Wood, 1g-1.5g of Blood Dracaena, 3g-9g of Leech, 6g-12g of Deer Horn Glue, 10g-20g of Drynaria, 6g-15g of Dipsacus asper, 10g-15g of Natural Copper, 5g-15g of Polygonum multiflorum, 6g of Eupolyphaga, 3g-10g of Corydalis, 10g-15g of Ganoderma Lucidum, and 10g of Patchouli.

2. A Chinese medicine formula for treating bone erosion according to claim 1, characterized in that: The mass ratio of Chuanxiong, Sappan wood and Corydalis is 1:1:

1.

3. A Chinese medicine formula for treating bone erosion according to claim 1, characterized in that: The main rhizome of Chuanxiong should be fresh, insect-free and well-dried. Wash and dry Chuanxiong, then cut into small pieces for later use.

4. A Chinese medicine formula for treating bone erosion according to claim 1, characterized in that: The Sanguisorba officinalis should be of full texture and bright color. Either the root or the whole plant can be used as medicine. Wash it, cut it into small pieces or chop it, dry it and set aside.

5. A Chinese medicine formula for treating bone erosion according to claim 1, characterized in that: The leeches used are plump, intact and bright red in color.

6. A Chinese medicine formula for treating bone erosion according to claim 1, characterized in that: The drynaria used should be hard in texture, free of insects and mildew. Wash it, dry it, cut it into small pieces for later use.

7. A Chinese medicine formula for treating bone erosion according to claim 1, characterized in that: The whole plant or the above-ground part of the Dipsacus asper is mainly used. Select fresh and tender Dipsacus asper without disease and insect pests. Wash and dry the Dipsacus asper. The whole plant can be dried or chopped for later use.

8. A method for preparing a Chinese medicine formula for treating bone erosion, characterized in that The method comprises the following steps: Step 1: Prepare the ingredients Prepare 3g-10g of Chuanxiong, 3g-9g of Su Mu, 1g-1.5g of Sanguisorba officinalis, 3g-9g of Hirudo, 6g-12g of Deer Horn Glue, 10g-20g of Drynaria, 6g-15g of Dipsacus asper, 10g-15g of Natural Copper, 5g-15g of Achyranthes bidentata, 6g of Eupolyphaga sinensis, 3g-10g of Corydalis yanhusuo, 10g-15g of Ganoderma lucidum, and 10g of Patchouli, for a total of 13 doses. Step 2: First Decoction Preparation Put the above Chinese medicinal materials into a ceramic container, add water and soak for half an hour, boil over high heat and then simmer for 12-30 minutes until the medicinal juice presents a rich color and aroma, and pour out the first decoction; Step 3: Second Decoction Preparation Add cold boiled water or warm water to the ceramic container in step 2 again, and continue to soak the newly cooked residue until the water just soaks the residue. Simmer on low heat for 5-10 minutes after the water boils. Pour out the second decoction, mix the two decoctions together, and take it warm twice a day, morning and evening, one dose per day.

9. The method for preparing a traditional Chinese medicine formula for treating bone erosion according to claim 8, characterized in that: The first decoction prepared in step 2 can be filtered out through a clean filter or cloth.