A peristaltic debriding catheter and method of use thereof

Abstract

The application discloses a peristaltic thrombus breaking and moving suction catheter and a use method thereof, and relates to the technical field of interventional medical devices. The peristaltic thrombus breaking and moving suction catheter comprises a catheter body, the catheter body comprises a suction channel and an adjusting channel, and the adjusting channel is arranged close to the suction channel. The adjusting channel is provided with a peristaltic structure, the peristaltic structure comprises multiple adjusting sections arranged along the axial direction of the catheter body, the expansion degree between the two ends of the adjusting section is adjustable, when the thrombus is sucked, the intermittent adjusting section is pressed and squeezed when expanding, the part with the maximum expansion degree of the two adjacent adjusting sections is not adjacent, and the adjusting section makes part of the channel wall of the suction channel have a corrugated structure along the axial direction. And the position with the maximum expansion degree of the adjusting section is different each time the expansion degree of the adjusting section is adjusted, so that the channel wall of the suction channel forms a dynamic corrugated movement (that is, a surface movement similar to the peristaltic movement of the intestines and stomach), thereby enhancing the moving force of the thrombus.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of interventional medical devices, in particular to a peristaltic thrombus breaking and moving catheter and a use method thereof. BACKGROUND

[0002] ADAPT technology (A Direct Aspiration first-Pass Technology, ADAPT) is an endovascular treatment method taking direct aspiration as a thrombus removal technology. The main advantages of ADAPT technology are that the operation is simpler, the opening time is shorter, the bleeding rate is lower, the safety is relatively high, the proportion of three-level recanalization is increased, and the thrombus distal escape event is reduced. However, the biggest disadvantage is that part of the cases cannot be in place or the thrombus is difficult to aspirate due to vascular stenosis. In the case of vascular stenosis or complex lesions, the thrombus may be difficult to be effectively aspirated, thereby reducing the effectiveness of the technology. Some large hard thrombi are prone to blockage in the blood vessel and cause pipe jamming, thereby affecting the recanalization of the blood vessel, requiring in vitro pipe through or multiple pipe replacement, and after pipe jamming occurs, the catheter is withdrawn from the human body, which is extremely complex to operate, the thrombus is prone to distal escape, and the operator needs to be more careful to avoid more unnecessary risks caused by pipe jamming. SUMMARY

[0003] The present application aims to solve one of the above technical problems in the prior art. To this end, the present application provides a peristaltic thrombus breaking and moving catheter.

[0004] The present application also provides a use method of the peristaltic thrombus breaking and moving catheter.

[0005] According to the embodiments of the first aspect of the present application, a peristaltic thrombus breaking and moving catheter is provided, which comprises a catheter body, the catheter body comprising an aspiration channel and an adjusting channel, the adjusting channel being adjacent to the aspiration channel; a peristaltic structure, at least part of the adjusting channel being provided with the peristaltic structure, the peristaltic structure comprising a plurality of adjusting segments arranged along the axial direction of the catheter body, the expansion degree between the two ends of the adjusting segment being adjustable, the adjusting segment being squeezed when expanding, the part with the largest expansion degree of the adjacent two adjusting segments not being adjacent, and the adjusting segment making part of the channel wall of the aspiration channel have a corrugated structure along the axial direction.

[0006] The above-mentioned peristaltic thrombus crushing and removing suction catheter has at least the following beneficial effects: the adjusting channel is arranged in the catheter body, and the peristaltic structure is arranged in part or all of the adjusting channel; the peristaltic structure adjusts the local width of the suction channel through a plurality of adjusting segments with adjustable expansion degrees; the expansion degree of the adjusting segments is adjusted intermittently during the thrombus suction operation; the parts with the maximum expansion degrees of the two adjacent adjusting segments are not adjacent; the part of the suction channel wall has a wave structure in the axial direction; and the position with the maximum expansion degree of the adjusting segments is different each time the expansion degree of the adjusting segments is adjusted, so that the channel wall of the suction channel forms a dynamic wave movement (i.e., a surface movement similar to the peristaltic movement of the intestines and stomach), thereby enhancing the moving force of the thrombus; in addition, the channel wall with the dynamic wave movement can extrude the thrombus during the peristaltic movement, so that the thrombus is crushed or deformed, thereby avoiding the catheter blockage.

[0007] According to the first aspect of the present application, the peristaltic thrombus crushing and removing suction catheter has the following beneficial effects: the catheter body includes an outer tube layer, an adjusting channel, and a suction channel for sucking the thrombus, and the adjusting channel is arranged close to the outer tube layer; the peristaltic structure is arranged in at least part of the adjusting channel, and the peristaltic structure includes a plurality of adjusting segments arranged in the axial direction of the catheter body; the expansion degree between the two ends of the adjusting segment can be adjusted; the adjusting segment adjusts the surface shape of the outer tube layer when it expands; the parts with the maximum expansion degrees of the two adjacent adjusting segments are not adjacent; and the adjusting segment makes part of the surface of the outer tube layer have a wave structure in the axial direction.

[0008] The peristaltic broken plug removing and suction catheter has at least the following beneficial effects: an adjusting channel is arranged at a position close to the outer tube layer of the catheter body, and a peristaltic structure is arranged in part or all of the adjusting channel; the peristaltic structure adjusts the surface shape of the outer tube layer through a plurality of adjusting segments with adjustable expansion degrees; the expansion degrees of the adjusting segments are adjusted intermittently during the movement of the catheter body in the blood vessel; the positions with the maximum expansion degrees of the two adjacent adjusting segments are not adjacent, so that part of the surface of the outer tube layer has a wave structure in the axial direction; and the positions with the maximum expansion degrees of the adjusting segments are changed each time the expansion degrees of the adjusting segments are adjusted, so that the channel wall of the suction channel forms a dynamic wave movement (i.e., a surface movement similar to the peristaltic movement of the intestines and stomach). For the suction of intracranial distal thrombus, a long and complex tortuous blood vessel needs to be passed, and after the conventional suction catheter is in place, a certain tension is generated; after the suction operation is performed, the tension between the catheter and the blood vessel is increased, and part of the catheter may be difficult to withdraw. The catheter body is additionally provided with a peristaltic structure, and during the use before the catheter is in place, the peristaltic reciprocating movement of the surface of the outer tube layer can eliminate part of the tension, so as to avoid increasing the tension of the catheter body or increasing the risk of catheter withdrawal.

[0009] The peristaltic broken plug removing and suction catheter according to the first aspect of the present application, the adjusting segment comprises at least two expansion tubes, the expansion tubes are annular, and the suction channel passes through the expansion tubes.

[0010] The peristaltic broken plug removing and suction catheter according to the first aspect of the present application, the diameter of the expansion tube is D, and the center distance between the two adjacent expansion tubes is greater than or equal to 1.5D.

[0011] The peristaltic broken plug removing and suction catheter according to the first aspect of the present application, the number of the expansion tubes is N, when the number of the expansion tubes is more than two, the N is a multiple of 2, the number of the expansion tubes between the expansion tube with the maximum expansion degree and the expansion tube with the minimum expansion degree is n, and n=(N-2) / 2.

[0012] The peristaltic broken plug removing and suction catheter according to the first aspect of the present application, the number of the expansion tubes is at least four, and the expansion degrees of the expansion tubes gradually decrease from the expansion tube with the maximum expansion degree to the expansion tube with the minimum expansion degree.

[0013] The peristaltic broken plug removing and suction catheter according to the first aspect of the present application, in the adjusting segment, only one of the expansion tubes has the maximum expansion degree, and the position of the expansion tube with the maximum expansion degree is changed once each time the expansion degree of the adjusting segment is adjusted.

[0014] According to the peristaltic broken plug moving plug suction catheter of the first aspect of the present application, the position of the inflation tube with the largest inflation degree changes towards the proximal end of the catheter body, and the position of the inflation tube with the largest inflation degree changes in the following manner: the inflation degree of the inflation tube adjacent to the inflation tube with the largest inflation degree in the last time becomes the largest.

[0015] According to the peristaltic broken plug moving plug suction catheter of the first aspect of the present application, the position of the inflation tube with the largest inflation degree changes towards the distal end of the catheter body, and the position of the inflation tube with the largest inflation degree changes in the following manner: the inflation degree of the inflation tube adjacent to the inflation tube with the largest inflation degree in the last time becomes the largest.

[0016] According to the second aspect of the present application, a method for using a peristaltic broken plug moving plug suction catheter is provided, comprising the following steps:

[0017] Selecting a catheter body matching the diameter of the blood vessel;

[0018] Passing the catheter body equipped with a peristaltic structure through the arterial approach and delivering it to the lesion position of the target blood vessel;

[0019] Starting the suction work of the device externally providing suction force, providing negative pressure suction force for the catheter body, and under the action of the negative pressure suction force, the thrombus enters the catheter body and is then removed from the blood vessel through the catheter body;

[0020] Stopping the suction work of the device externally providing suction force, and withdrawing the catheter body from the human body;

[0021] Wherein, if the peristaltic structure is close to the inner layer of the catheter body, the flow medium is injected into the inflation tube to adjust the inflation degree of the inflation tube during the suction process of the catheter body, and the position of the inflation tube with the largest inflation degree changes once every time the adjustment section adjusts the inflation degree;

[0022] If the peristaltic structure is close to the outer layer of the catheter body, the flow medium is injected into the inflation tube to adjust the inflation degree of the inflation tube during the pushing and pulling process of the catheter body in the blood vessel, and the position of the inflation tube with the largest inflation degree changes once every time the adjustment section adjusts the inflation degree.

[0023] Additional aspects and advantages of the present application will be partially given in the following description, partially will become obvious from the following description, or will be understood by the practice of the present application. BRIEF DESCRIPTION OF DRAWINGS

[0024] The present application will be further described below in combination with the drawings and examples;

[0025] Figure 1is a schematic diagram of a suction catheter structure in the embodiment of the present application;

[0026] Figure 2 is Figure 1 is an enlarged schematic diagram at A in FIG. 1;

[0027] Figure 3 is Figure 1 is a sectional view along direction B-B in FIG. 1;

[0028] Figure 4 is a schematic diagram of a peristaltic structure in the embodiment of the present application Figure 1 ;

[0029] Figure 5 is a schematic diagram of a peristaltic structure in the embodiment of the present application Figure 2 ;

[0030] Figure 6 is a schematic diagram of a peristaltic structure in the embodiment of the present application Figure 3 ;

[0031] Figure 7 is a schematic diagram of a peristaltic structure in the embodiment of the present application Figure 4 ;

[0032] Figure 8 is a schematic diagram of a catheter body being pulled in a blood vessel in the embodiment of the present application Figure 1 ;

[0033] Figure 9 is a schematic diagram of a catheter body being pulled in a blood vessel in the embodiment of the present application Figure 2 ;

[0034] Figure 10 is a schematic diagram of a catheter body being pulled in a blood vessel in the embodiment of the present application Figure 3 .

[0035] Reference signs:

[0036] catheter seat 100, catheter body 200, suction channel 201, radiopaque ring 202, hydrophilic coating 210, outer tube layer 220, braided layer 230, spring winding layer 240, adjusting channel 250, first expansion tube 251, third expansion tube 2521, fourth expansion tube 2522, second expansion tube 253, inner liner 260. DETAILED DESCRIPTION

[0037] This part will describe the specific embodiments of the present application in detail, the preferred embodiments of the present application are shown in the drawings, the role of the drawings is to supplement the description of the text part with figures, so that people can intuitively and visually understand each technical feature and the overall technical scheme of the present application, but it cannot be understood as a limitation on the protection scope of the present application.

[0038] In the description of the present application, it should be understood that the orientation description, such as the orientation or position relationship indicated by up, down, front, back, left, right and the like, is based on the orientation or position relationship shown in the drawings, and is only for the purpose of facilitating the description of the present application and simplifying the description, and does not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present application.

[0039] In the description of the present application, the meaning of several is one or more, the meaning of multiple is more than two, greater than, less than, more than, etc. are understood as not including the number, above, below, within, etc. are understood as including the number. If it is described as first, second, it is only for the purpose of distinguishing technical features, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features or implicitly indicating the sequence of indicated technical features.

[0040] In the description of the present application, unless otherwise explicitly limited, the words such as setting, installing, connecting, etc. should be broadly understood, and those skilled in the art can reasonably determine the specific meaning of the above words in the present application in combination with the specific content of the technical solution.

[0041] In order to more clearly describe the present application, the meanings of the two concepts of "distal end" and "proximal end" are defined here. The above concepts are common terms in the field of interventional medical devices. Specifically, "distal end" means the end far from the operator during the operation, and "proximal end" means the end close to the operator during the operation. Of course, for a single device object, "proximal end" can also be used to describe the end close to the operator, and "distal end" can also be used to describe the end far from the operator.

[0042] Thrombus aspiration is an interventional treatment method, which inserts a catheter into the blood vessel, uses special instruments in the thrombosed blood vessel to extract the thrombus, and restores the unobstructed blood flow. This technology is mainly used for the treatment of acute coronary syndrome and cerebral infarction and other thrombotic diseases.

[0043] The principle of thrombus aspiration is to use special catheters to cut or extract thrombus, make the blood vessel unobstructed, and restore normal blood flow. The catheter is inserted into the blood vessel, and the instrument for cutting or sucking out the thrombus is sent into the blood vessel after positioning at a proper position. These instruments usually include special catheters and suction tubes, and instruments that can penetrate and grasp the thrombus. Under the operation of the instrument, the thrombus is separated, captured and sucked out of the body, so as to restore normal blood flow.

[0044] ADAPT technology (A Direct Aspiration first-Pass Technology, ADAPT) is an endovascular treatment method using direct aspiration as a thrombus extraction technique. This technique requires the use of a trackable, large-diameter aspiration catheter for direct aspiration thrombus extraction. In 2015, the publication of five clinical trials of endovascular treatment of stroke confirmed that patients with acute large artery occlusion could benefit from endovascular treatment. This milestone established the first-line treatment of mechanical thrombectomy for large vessel occlusion and marked the advent of the thrombectomy era.

[0045] In the past two years, with the advent of ADAPT technology, stent thrombectomy or catheter aspiration has become a hot topic widely discussed in clinical practice. In 2019, the AHA / ASA guidelines were updated, and ADAPT technology was listed as an IB level recommended therapy, providing strong evidence support for the application of ADAPT technology in clinical practice.

[0046] However, the biggest drawback of ADAPT technology is that it cannot be placed in some cases or the thrombus is difficult to aspirate due to vascular stenosis. In the case of vascular stenosis or complex lesions, the thrombus may be difficult to aspirate effectively, thereby reducing the effectiveness of the technology. Some large and hard thrombi are prone to blockage in the blood vessel and cause catheter jamming, thereby affecting blood vessel recanalization.

[0047] Therefore, the embodiments of the present application provide a peristaltic thrombus crushing and moving thrombus aspiration catheter, which can effectively solve the problem of thrombus blockage or difficult aspiration.

[0048] Reference Figure 1 The peristaltic thrombus crushing and moving thrombus aspiration catheter according to the first aspect of the present application comprises a catheter body 200 and a peristaltic structure. The catheter body 200 comprises an aspiration channel 201 and an adjusting channel 250, and the adjusting channel 250 is adjacent to the aspiration channel 201. At least part of the adjusting channel 250 is provided with a peristaltic structure, and the peristaltic structure comprises a plurality of adjusting segments arranged in the axial direction of the catheter body 200. The expansion degree between the two ends of the adjusting segment is adjustable. When the adjusting segment expands, it presses the aspiration channel 201. The part with the largest expansion degree of the two adjacent adjusting segments is not adjacent. The adjusting segment makes part of the channel wall of the aspiration channel 201 have a corrugated structure in the axial direction.

[0049] The corrugated structure is composed of continuous and alternating convex and concave parts on the inner wall of the catheter body 200.

[0050] The peristaltic structure adjusts the local width of the aspiration channel through a plurality of adjusting segments with adjustable expansion degree. During the aspiration of the thrombus, the expansion degree of the adjusting segment is adjusted intermittently, and the adjusting frequency of the adjusting segment can be the same as the aspiration frequency.

[0051] All the adjustment segments simultaneously perform the expansion degree adjustment, after the expansion degree adjustment is completed, the part with the largest expansion degree of the adjacent two adjustment segments is not adjacent, so that part of the channel wall of the suction channel 201 has a corrugated structure along the axial direction, and the position with the largest expansion degree of the adjustment segment is different each time the expansion degree adjustment of the adjustment segment is performed, so that the channel wall of the suction channel 201 forms a dynamic corrugated movement (that is, a surface movement similar to the "peristalsis" of the intestines and stomach), thereby enhancing the moving force of the thrombus; in addition, the channel wall in the dynamic corrugated movement can extrude the thrombus during the suction of the thrombus, so that the thrombus is broken or deformed, thereby avoiding pipe blockage.

[0052] In some embodiments, the peristaltic thrombus suction and removal device further comprises a stress release tube and a catheter seat 100, the stress release tube is sleeved on the proximal end of the catheter body 200, and the stress release tube is connected with the catheter seat 100, the stress release tube is used for facilitating the control of the catheter body 200 during the operation of the operator, so as to avoid the breakage of the catheter body 200 due to stress concentration.

[0053] As shown in FIG. 1, the catheter body 200 comprises a suction channel 201, an inner lining layer 260, an adjustment channel 250, a spring winding layer 240, a braided layer 230 and an outer tube layer 220 from inside to outside, that is, the suction channel 201 and the adjustment channel 250 are separated by the inner lining layer 260. Figure 3

[0054] The inner lining layer 260 is made of PTFE material, and the smooth and lubricated suction channel 201 is established through the inner lining layer 260, which is beneficial to the passage of other instruments.

[0055] The adjustment channel 250 is composed of TPU.

[0056] The outer tube layer 220 is composed of TPU and Pebax, and the appearance layer contains barium sulfate material which can be developed under X-ray. The outer tube layer 220 has a stronger hardness change from soft to hard from the distal end to the proximal end, the distal end maintains soft to position performance, and the proximal end provides higher support.

[0057] As shown in FIG. 1, the catheter body 200 is provided with a developing ring 202 at the distal end, the developing ring 202 is made of platinum-iridium alloy, and the developing ring 202 can be developed under X-ray. Figure 2 The spring winding layer 240 and the braided layer 230 are made of stainless steel wire which is wound or braided, and the winding wire and the braided wire include but are not limited to original round wire, flat wire, round and flat mixed winding / braiding. The spring winding layer 240 and the braided layer 230 are used to enhance the structure of the catheter body, and the winding pitch and the braiding density can be changed from sparse to dense from the distal end to the proximal end, so as to have better soft and hard performance.

[0058] ​​

[0059] In some specific embodiments, the effective length of the catheter body 200 is 110-150 cm, the length of the distal soft part of the catheter body 200 is set to 10-30 cm, the length of the hydrophilic coating 210 on the surface of the outer tube layer 220 of the catheter body 200 is 50-80 cm, the diameter of the suction channel 201 is 1.0-2.5 mm, and the outer diameter of the catheter body 200 is 1.2-3.3 mm.

[0060] In some examples, the adjustment section includes at least two expansion tubes, each of which is annular. The suction channel 201 passes through the expansion tubes, and the expansion tubes at the same position of all the adjustment sections are connected.

[0061] like Figure 4 As shown, in some embodiments shown in the first aspect of the present application, the adjustment section includes a first expansion tube 251 and a second expansion tube 253, the first expansion tubes 251 of all adjustment sections are connected, and the second expansion tubes 253 of all adjustment sections are connected, and the first expansion tube 251 and the second expansion tube 253 are sleeved outside the suction channel 201.

[0062] In some embodiments, the expansion degree of the first expansion tube 251 and the second expansion tube 253 can be adjusted by positive and negative pressure. By connecting the first expansion tube 251 or the second expansion tube 253 to a variable frequency negative pressure suction device, the intermittent frequency conversion of positive and negative pressure causes the first expansion tube 251 and the second expansion tube 253 to alternately inflate and deflate. This alternating process creates a dynamic ripple curve on the surface of the suction channel 201, creating a surface motion similar to gastrointestinal "peristalsis," thereby enhancing the ability to transport blood clots.

[0063] When positive pressure is applied to the first expansion tube 251, negative pressure is applied to the second expansion tube 253; when negative pressure is applied to the first expansion tube 251, positive pressure is applied to the second expansion tube 253; each time the expansion degree is adjusted, the position of the maximum expansion degree of the adjustment section will change, that is, the first expansion tube 251 and the second expansion tube 253 alternately become the expansion tubes with the maximum expansion degree, thereby achieving peristaltic squeezing of the thrombus in the suction channel 201 to prevent the thrombus from getting stuck in the tube.

[0064] During the peristaltic extrusion and aspiration of thrombus, for large and irregularly shaped thrombi, the expansion tube introduced into the positive pressure part during the peristaltic process will squeeze the thrombus, causing it to break or deform. The maximum size of the squeezed thrombus monomer is smaller than the inner diameter of the catheter body 200, avoiding tube jamming.

[0065] In some embodiments, a flowable medium may be introduced into the first expansion tube 251 and the second expansion tube 253 to adjust the expansion degree of the expansion tube. The filling and deflation of the expansion tube may be achieved by increasing or decreasing the medium in the expansion tube. The medium may be a flowable fluid such as water or gas.

[0066] In this embodiment, when performing thrombectomy, the catheter body 200 still uses negative pressure suction (syringe or negative pressure suction pump) as the main means of thrombus suction, and the peristaltic type of the suction channel 201 serves as an auxiliary function to prevent tube jamming and enhance the thrombus suction speed.

[0067] In some embodiments, the diameter of the expansion tube is D, and the center distance between two adjacent expansion tubes is greater than or equal to 1.5D. If two expansion tubes are directly close together, it is not conducive to adjusting the expansion degree of the expansion tubes. A certain adjustment gap should be set between the two adjacent expansion tubes. That is, the center distance between the two adjacent expansion tubes should be greater than or equal to 1.5D. This makes the corrugated structure formed on the channel wall of the suction channel 201 more continuous and provides sufficient expansion adjustment space for the expansion tubes.

[0068] Suppose the number of expansion tubes is N. When the number of expansion tubes exceeds 2, N is a multiple of 2. Suppose the number of expansion tubes between the expansion tube with the largest expansion degree and the expansion tube with the smallest expansion degree is n, n=(N-2) / 2.

[0069] In some embodiments, the number of the expansion tubes is at least 4, and the expansion degrees of the expansion tubes decrease gradually from the expansion tube with the largest expansion degree to the expansion tube with the smallest expansion degree.

[0070] When the number of expansion tubes in each adjustment section is 6, when the expansion degree is adjusted, the number of expansion tubes between the expansion tube with the largest expansion degree and the expansion tube with the lowest expansion degree is 2, and the expansion degrees of the expansion tubes between the expansion tube with the largest expansion degree and the expansion tube with the lowest expansion degree gradually decrease.

[0071] In the adjustment section, only one expansion tube has the largest expansion degree. Each time the adjustment section performs an expansion degree adjustment, the position of the expansion tube with the largest expansion degree is changed.

[0072] In some embodiments, the position of the expansion tube with the largest expansion degree is changed toward the proximal end of the catheter body 200 , and the position of the expansion tube with the largest expansion degree is changed in such a way that the expansion degree of the expansion tube adjacent to the expansion tube with the largest expansion degree becomes the largest.

[0073] In other embodiments, the position of the expansion tube with the largest expansion degree is changed toward the distal end of the catheter body 200 , and the position of the expansion tube with the largest expansion degree is changed in such a way that the expansion degree of the expansion tube adjacent to the expansion tube with the largest expansion degree last time becomes the largest.

[0074] like Figure 5As shown, in some embodiments of the first aspect of the present application, the adjusting section includes a first expansion tube 251, a second expansion tube 253, a third expansion tube 2521, and a fourth expansion tube 2522. The third expansion tube 2521 and the fourth expansion tube 2522 are distributed on both sides of the first expansion tube 251, and the third expansion tube 2521 is between the first expansion tube 251 and the second expansion tube 253.

[0075] When the first expansion tube 251 is in the state of the largest expansion degree, the second expansion tube 253 has the smallest expansion degree, the third expansion tube 2521 has an expansion degree greater than that of the second expansion tube 253, but the expansion degree of the third expansion tube 2521 is smaller than that of the first expansion tube 251, the fourth expansion tube 2522 has an expansion degree greater than that of the second expansion tube 253, but the expansion degree of the fourth expansion tube 2522 is smaller than that of the first expansion tube 251, and the fourth expansion tube 2522 is adjacent to the second expansion tube 253 of the next adjusting section.

[0076] Therefore, the expansion degrees of the first expansion tube 251, the third expansion tube 2521, and the second expansion tube 253 gradually decrease, that is, the expansion degree of the expansion tube gradually decreases from the expansion tube with the largest expansion degree to the expansion tube with the lowest expansion degree.

[0077] When the expansion degree of the next adjusting section is adjusted, the expansion tube with the largest expansion degree changes from the first expansion tube 251 to the third expansion tube 2521, the fourth expansion tube 2522 has the smallest expansion degree, the first expansion tube 251 has an expansion degree greater than that of the fourth expansion tube 2522, but the expansion degree of the first expansion tube 251 is smaller than that of the third expansion tube 2521, the expansion degree of the second expansion tube 253 is smaller than that of the third expansion tube 2521, and the fourth expansion tube 2522 is adjacent to the second expansion tube 253 of the next adjusting section.

[0078] At this time, the part with the largest expansion degree in the adjusting section is switched from the first expansion tube 251 to the third expansion tube 2521, and the expansion degree of the adjusting section is adjusted intermittently to realize the peristalsis of the corrugated structure, thereby forming a dynamic corrugated curve on the surface of the channel wall of the suction channel 201, and forming a surface movement similar to the "peristalsis" of the intestines and stomach.

[0079] In the second aspect of the present application, the peristaltic thrombus extraction catheter includes a catheter body 200 and a peristaltic structure. In this embodiment, the catheter body 200 includes an outer tube layer 220, an adjusting channel 250, and a suction channel 201 for extracting thrombus. The adjusting channel 250 is adjacent to the outer tube layer 220, and at least part of the adjusting channel 250 is provided with the peristaltic structure, that is, the peristaltic structure is adjacent to the outer tube layer 220.

[0080] The peristaltic structure includes multiple adjustment segments arranged along the axial direction of the catheter body 200, the expansion degree between the two ends of the adjustment segment is adjustable, the adjustment segment adjusts the surface shape of the outer tube layer 220 when it expands, and the parts with the maximum expansion degree of the two adjacent adjustment segments are not adjacent, and the adjustment segment makes part of the surface of the outer tube layer 220 have a wave structure along the axial direction.

[0081] In the second aspect, the adjustment channel 250 is arranged at the position close to the outer tube layer 220 of the catheter body 200, and the peristaltic structure is arranged in part or all of the adjustment channel 250. The peristaltic structure adjusts the surface shape of the outer tube layer 220 through multiple adjustment segments with adjustable expansion degree. During the movement of the catheter body 200 in the blood vessel, the expansion degree adjustment of the adjustment segment is performed intermittently. The parts with the maximum expansion degree of the two adjacent adjustment segments are not adjacent, so that part of the surface of the outer tube layer 220 has a wave structure along the axial direction, and the position with the maximum expansion degree of the adjustment segment is changed each time the expansion degree adjustment of the adjustment segment is performed (that is, the position with the maximum expansion degree is changed each time the expansion degree adjustment is performed), so that the channel wall of the suction channel 201 forms a dynamic wave movement (that is, a surface movement similar to the peristaltic movement of the intestines and stomach).

[0082] For intracranial distal thrombus suction, a long and complex tortuous blood vessel will be experienced. After the conventional suction catheter is in place, there will be a certain tension. After the suction operation is performed, the tension between the catheter and the blood vessel will increase, and part of the catheter may have difficulty in withdrawing. The catheter body 200 of the present application is additionally provided with a peristaltic structure. During the use before being in place, the peristaltic reciprocating movement of the surface of the outer tube layer 220 will eliminate part of the tension, thereby avoiding increasing the tension of the catheter body 200 or increasing the risk of catheter withdrawal.

[0083] The adjustment segment includes at least two expansion tubes, the expansion tube is annular, the suction channel 201 passes through the expansion tube, and the expansion tubes at the same position of all adjustment segments are connected.

[0084] The diameter of the expansion tube is D, and the center distance between the two adjacent expansion tubes is greater than or equal to 1.5D.

[0085] The number of expansion tubes is N, when the number of expansion tubes is more than 2, N is a multiple of 2, the number of expansion tubes between the expansion tube with the maximum expansion degree and the expansion tube with the minimum expansion degree is n, n=(N-2) / 2.

[0086] The number of expansion tubes is at least 4, and the expansion degree of the expansion tube gradually decreases from the expansion tube with the maximum expansion degree to the expansion tube with the minimum expansion degree.

[0087] In the adjustment segment, only one expansion tube has the maximum expansion degree, and the position of the expansion tube with the maximum expansion degree is changed once each time the expansion degree adjustment of the adjustment segment is performed.

[0088] The position of the inflation tube with the largest degree of inflation is changed in the proximal direction of the catheter body 200, and the position of the inflation tube with the largest degree of inflation is changed in the following manner: the degree of inflation of the inflation tube adjacent to the inflation tube with the largest degree of inflation in the last time becomes the largest.

[0089] The position of the inflation tube with the largest degree of inflation is changed in the distal direction of the catheter body 200, and the position of the inflation tube with the largest degree of inflation is changed in the following manner: the degree of inflation of the inflation tube adjacent to the inflation tube with the largest degree of inflation in the last time becomes the largest.

[0090] As shown in Figure 6 some embodiments shown by the second aspect of the present application, the adjustment section includes a first inflation tube 251 and a second inflation tube 253, the first inflation tubes 251 of all the adjustment sections are communicated, the second inflation tubes 253 of all the adjustment sections are communicated, and the first inflation tube 251 and the second inflation tube 253 are sleeved outside the suction channel 201.

[0091] As shown in Figure 7 some embodiments shown by the second aspect of the present application, the adjustment section includes a first inflation tube 251, a second inflation tube 253, a third inflation tube 2521 and a fourth inflation tube 2522, the third inflation tube 2521 and the fourth inflation tube 2522 are distributed on both sides of the first inflation tube 251, and the third inflation tube 2521 is between the first inflation tube 251 and the second inflation tube 253.

[0092] It should be noted that the adjustment section in the second aspect of the application is the same as the adjustment section in the first aspect of the application, and the related principles will not be described here.

[0093] As shown in Figure 8 when the catheter body 200 needs to be separated from the human body, the external stretching force and the friction force of the blood vessel will cause the catheter body 200 to deform, resulting in the situation that the stress is concentrated on the inner bending part of the blood vessel; as Figure 9 shown, when the catheter body 200 needs to be pushed into the blood vessel, the external pushing force and the friction force of the blood vessel wall will cause the catheter body 200 to deform, resulting in the situation that the stress is concentrated on the outer bending part of the blood vessel.

[0094] As shown in Figure 10 the use process of the peristaltic broken-stub moving-stub suction catheter of the second aspect of the present application before being in place, due to the setting of the peristaltic structure, the outer surface of the catheter body 200 is in a peristaltic reciprocating motion state, which can eliminate part of the tension and avoid increasing the tension of the catheter body 200, thereby effectively reducing the risk of catheter withdrawal.

[0095] The present application also provides a use method of the peristaltic broken-stub moving-stub suction catheter, and the specific steps are as follows:

[0096] selecting a catheter body 200 matching the diameter of the blood vessel;

[0097] passing the catheter body 200 equipped with the peristaltic structure through the arterial approach and delivering it to the lesion site of the target blood vessel;

[0098] the device providing suction force externally starts the suction work, providing negative pressure suction force for the catheter body 200, and the thrombus enters the catheter body 200 under the action of the negative pressure suction force and is then removed from the blood vessel through the catheter body 200;

[0099] the device providing suction force externally stops the suction work, and the catheter body 200 is withdrawn from the human body;

[0100] If the peristaltic structure is close to the inner layer of the catheter body 200, the flow medium is injected into the inflation tube to adjust the inflation degree of the inflation tube during the suction process of the catheter body 200, and the position of the inflation tube with the largest inflation degree is changed once for each inflation degree adjustment of the adjustment section;

[0101] If the peristaltic structure is close to the outer layer of the catheter body 200, the flow medium is injected into the inflation tube to adjust the inflation degree of the inflation tube during the pushing and pulling process of the catheter body 200 in the blood vessel, and the position of the inflation tube with the largest inflation degree is changed once for each inflation degree adjustment of the adjustment section.

[0102] The embodiments of the present application are described in detail above in combination with the drawings, but the present application is not limited to the above embodiments, and various changes can be made within the knowledge of those skilled in the art in the technical field without departing from the purpose of the present application.

Claims

1. A peristaltic debriding and evacuating catheter, comprising: The catheter body comprises a suction channel and an adjusting channel adjacent to the suction channel. The adjusting channel is provided with a peristaltic structure, which comprises a plurality of adjusting segments arranged along the axial direction of the catheter body, the expansion degree between the two ends of the adjusting segment is adjustable, the adjusting segment is squeezed when expanded, the part with the maximum expansion degree of the two adjacent adjusting segments is not adjacent, and the adjusting segment makes part of the channel wall of the suction channel have a corrugated structure along the axial direction. The adjusting segment comprises at least two expansion tubes, the expansion tube is annular, the suction channel passes through the expansion tube, the expansion tubes at the same position of all adjusting segments are communicated, only one of the expansion tubes has the maximum expansion degree in the adjusting segment, and the position of the expansion tube with the maximum expansion degree changes once every time the expansion degree of the adjusting segment is adjusted. The catheter body comprises an outer tube layer, an adjusting channel and a suction channel for sucking thrombus, and the adjusting channel is adjacent to the outer tube layer.

2. A peristaltic debriding and evacuating catheter comprising: The adjusting channel is provided with a peristaltic structure, which comprises a plurality of adjusting segments arranged along the axial direction of the catheter body, the expansion degree between the two ends of the adjusting segment is adjustable, the adjusting segment adjusts the surface shape of the outer tube layer when expanded, the part with the maximum expansion degree of the two adjacent adjusting segments is not adjacent, and the adjusting segment makes part of the surface of the outer tube layer have a corrugated structure along the axial direction. The adjusting segment comprises at least two expansion tubes, the expansion tube is annular, the suction channel passes through the expansion tube, the expansion tubes at the same position of all adjusting segments are communicated, only one of the expansion tubes has the maximum expansion degree in the adjusting segment, and the position of the expansion tube with the maximum expansion degree changes once every time the expansion degree of the adjusting segment is adjusted. The diameter of the expansion tube is D, and the center distance between the two adjacent expansion tubes is greater than or equal to 1.5D. When the number of expansion tubes is more than two, the number N is a multiple of 2, and the number of expansion tubes between the expansion tube with the maximum expansion degree and the expansion tube with the minimum expansion degree is n, n=(N-2) / 2.

3. A peristaltic debriding catheter according to claim 1 or 2, characterised in that: The number of expansion tubes is at least four, and the expansion degree of the expansion tube gradually decreases from the expansion tube with the maximum expansion degree to the expansion tube with the minimum expansion degree.

4. A peristaltic broken plug milk expressing breast pump according to claim 1 or 2, characterised in that: The position change of the expansion tube with the maximum expansion degree changes towards the proximal end of the catheter body, and the position change of the expansion tube with the maximum expansion degree changes in the following way: the expansion degree of the expansion tube adjacent to the expansion tube with the maximum expansion degree changes to the maximum.

5. A peristaltic de-threading suction catheter according to claim 3, wherein: The position change of the expansion tube with the maximum expansion degree changes towards the distal end of the catheter body, and the position change of the expansion tube with the maximum expansion degree changes in the following way: the expansion degree of the expansion tube adjacent to the expansion tube with the maximum expansion degree changes to the maximum.

6. A peristaltic broken plug milk expressing breast pump according to claim 1 or 2, wherein: ​ 7. A peristaltic de-threading suction catheter according to claim 1 or 2, characterized in that: ​

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