Thrombus protector and thrombus protection catheter

Abstract

The invention relates to the technical field of catheter medical instruments, and provides a thrombus protector and a thrombus protection catheter. The device comprises a net bag, a guide rod, a ring body and a connecting wire, the net bag is provided with a containing cavity; two ends of the guide rod are respectively a first end and a second end; the first end is fixedly connected with the inner wall of the bottom of the accommodating cavity; the second end is connected with the seat body; the ring body extends along the edge of the opening of the accommodating concave cavity; the edge of the opening of the accommodating concave cavity is fixed on the ring body; the ring body is arranged on the outer side of the guide rod in a sleeving manner; the ring body can be bent and deformed under the action of external force; after the external force is removed, the ring body can recover to be annular; a thrombus inlet channel for thrombus to enter the accommodating cavity is formed between the ring body and the guide rod; the connecting wire is connected with the ring body and the second end; the ring body is located between the first end and the second end.

Description

Technical Field

[0001] The present invention belongs to the technical field of catheter medical devices, and more specifically, relates to a thrombus protector and a thrombus protection catheter. Background Art

[0002] Ischemic stroke, also known as cerebral infarction, refers to blockage or severe stenosis of cerebral blood vessels due to cerebral blood circulation disorders, resulting in reduced cerebral blood flow or insufficient cerebral oxygen supply, causing death of brain tissue in the cerebral blood supply area. About 20%-30% of strokes are related to atherosclerotic carotid artery stenosis. The surgical treatment of carotid artery stenosis mainly includes carotid endarterectomy (CEA) and carotid artery stenting (CAS). The use of distal embolic protection devices in carotid artery stenting can effectively reduce the incidence of embolic events caused by emboli detachment, and the use of thrombus removal protection devices (hereinafter referred to as embolic protection devices) for complete removal of emboli. This type of device has the advantage of being able to remove thrombi without interrupting blood flow and can be used for most patients.

[0003] Lower extremity arterial disease refers to a disease in which local ischemia of the body is caused by local stenosis or occlusion of lower extremity arteries. The main cause is atherosclerosis, and lesions related to atherosclerosis account for 90%-95% of all lesions. In lower extremity arterial disease, distal embolic protection devices are mainly used in volume reduction therapy to reduce vascular contents by removing plaques or thrombi, thereby reducing the incidence of distal embolic events.

[0004] Both of the above-mentioned diseases require distal embolic protection devices (thrombus protectors). Similar devices on the market have defects in the net bag structure after capturing thrombus fragments, so there is still a possibility that the captured emboli will escape. Summary of the invention

[0005] The purpose of the present invention is to provide a thrombus protector to solve the technical problem in the prior art that thrombus is easy to escape when being grabbed.

[0006] To achieve the above-mentioned purpose, the technical solution adopted by the present invention is to provide a thrombus protector, comprising: seat body; A net bag; the net bag has a receiving cavity; A guide rod; the two ends of the guide rod are respectively a first end and a second end; the first end is fixedly connected to the inner wall of the bottom of the accommodating cavity; the second end is connected to the seat body; A ring body; the ring body extends along the edge of the opening of the accommodating cavity; the edge of the opening of the accommodating cavity is fixed on the ring body; the ring body is sleeved on the outside of the guide rod; the ring body can be bent and deformed under the action of external force; after the external force is removed, the ring body can return to a ring shape; a thrombus entry channel for allowing thrombus to enter the accommodating cavity is formed between the ring body and the guide rod; A connecting wire; the connecting wire connects the ring body and the second end; the ring body is located between the first end and the second end.

[0007] Furthermore, the ring body is a memory alloy ring or an elastic ring.

[0008] Furthermore, the ring body is: a nickel-titanium alloy ring.

[0009] Furthermore, the connecting wire is: memory alloy wire.

[0010] Furthermore, the connecting wire is: nickel-titanium alloy wire.

[0011] Furthermore, the ring body and the net bag are connected by any one of welding, wire winding, knitting and bonding.

[0012] Furthermore, there are multiple connecting wires.

[0013] Furthermore, the number of the connecting wires is two.

[0014] Furthermore, a supporting space is formed between the plurality of connecting wires; the supporting space is communicated with the accommodating cavity; and the external space is communicated with the supporting space through the gap between any adjacent connecting wires.

[0015] Furthermore, along the extension direction of the guide rod from the first end to the second end, the cross section of the support space gradually narrows.

[0016] Furthermore, the net bag is: a metal woven net; or the net bag is: a porous polymer molding net.

[0017] Furthermore, the net bag is a nickel-titanium wire woven net.

[0018] Furthermore, it also includes: a first ring sleeved and fixed on the first end.

[0019] Furthermore, a connection between the net bag and the first end is clamped between the first ring and the first end.

[0020] Furthermore, the first ring is made of any one of platinum, platinum-iridium alloy, and gold.

[0021] Furthermore, it also includes: a second ring sleeved and fixed on the second end.

[0022] Furthermore, the second ring is made of any one of platinum, platinum-iridium alloy, and gold.

[0023] Furthermore, it also includes: a guide wire; one end of the guide wire is connected to the first end; and the other end of the guide wire is located outside the net bag.

[0024] Furthermore, it also includes: a containment tube, a traction wire, and a traction device arranged on the seat body; the openings at both ends of the containment tube are respectively a first opening and a second opening; the edge of the first opening is fixed on the ring body, and the ring body extends along the edge of the first opening; the traction device is connected to the edge of the second opening through the traction wire, and the traction wire can pull the edge of the second opening in a direction away from the first end to sleeve the containment tube on the outside of the connecting wire.

[0025] Furthermore, the containment cylinder can be folded and sleeved on the outer wall of the net bag.

[0026] Furthermore, the containment cylinder is an integral piece made of elastic material.

[0027] Furthermore, the containment cylinder is made of any one of nylon, pebax, and polyester film by blow molding.

[0028] Furthermore, the containment cylinder is provided with a plurality of through holes.

[0029] Furthermore, the traction device includes: a toggle switch; the toggle switch is slidably mounted on the seat; one end of the traction wire is connected to the toggle switch, and the other end of the traction wire is connected to the second opening edge of the containment cylinder.

[0030] Furthermore, the traction wire can be made of any one of nickel-titanium, stainless steel, and nylon ribbon wire.

[0031] Furthermore, a wire feeding channel is provided in the guide rod, and the traction wire passes through the wire feeding channel and is connected to the toggle switch.

[0032] Further, the guide rod includes: a hypotube and a sleeve; the hypotube and the sleeve are respectively connected to the seat body; one end of the hypotube is the first end, and the sleeve is sleeved on the other end of the hypotube; the end of the sleeve close to the first end is the second end; the wire feeding channel is formed between the sleeve and the hypotube.

[0033] Furthermore, the outer surface of the hypotube has a spiral groove formed by laser processing.

[0034] Furthermore, it also includes: an ultrasonic generator arranged on the base, and the ultrasonic generator is connected to the guide rod.

[0035] Furthermore, it also includes: a medicine bag arranged in the accommodating cavity and containing a thrombolytic drug.

[0036] Furthermore, the medicine bag has an opening; the opening is covered with a protective cover; the protective cover is rotatably arranged on the medicine bag; and the protective cover is connected to a pulling line for pulling and opening the protective cover.

[0037] Furthermore, a mesh is laid on the inner wall of the accommodating cavity; the mesh is fixedly connected to the inner wall of the accommodating cavity by a plurality of fasteners.

[0038] Furthermore, the mesh holes on the net body are smaller than the mesh holes on the net bag.

[0039] Furthermore, the mesh body and the inner wall of the accommodating cavity are spaced apart from each other.

[0040] Furthermore, the mesh holes on the net body and the mesh holes on the net bag are arranged alternately.

[0041] Furthermore, the inner wall of the net bag is covered with a thrombolytic drug coating for reducing thrombosis.

[0042] Furthermore, any adjacent grids on the net bag are rotatably connected to each other.

[0043] Furthermore, it also includes: a universal coupling structure; any adjacent grids on the net bag are rotatably connected via the universal coupling structure.

[0044] Furthermore, when the guide rod extends along the x-axis and the net bag is opened, in an axial section passing through the axis of the guide rod and vertically arranged, the trajectory of the outer wall of the net bag on one side of the x-axis is parallel to y=0.0001*x^3 +0.01*x^2−0.5*x (wherein, -85≤x≤19), and the trajectories of the outer walls of the net bag on both sides of the guide rod are axially symmetrical.

[0045] The present invention also provides a thrombus protection catheter, comprising: a tube body and the thrombus protector; the tube body has a tube cavity, and the net bag is received in the tube body.

[0046] The beneficial effects of the thrombus protector provided by the present invention are as follows: compared with the prior art, the thrombus protector provided by the present invention has a guide rod arranged on a seat body, and the two ends of the guide rod are respectively a first end and a second end, and the second end is connected to the seat body, and the user can move the guide rod by moving the seat body; the net bag has a accommodating cavity, and when the user releases the net bag into the blood vessel, the user can catch the thrombus in the blood vessel through the accommodating cavity; a ring body is fixed to the edge of the opening of the accommodating cavity, and the ring body extends along the edge of the opening of the accommodating cavity, so that the ring body can support the edge of the opening of the accommodating cavity; on the outside Under the action of force, the ring body can bend and deform, so that the ring body can be folded and stored under the action of external force, which is convenient for the folding and storage of the net bag; when the ring body is released into the blood vessel, the ring body can return to its ring shape to open the opening of the accommodating cavity, and the thrombus can enter the accommodating cavity from the opening of the accommodating cavity more easily; the first end of the guide rod is fixedly connected to the inner wall of the bottom of the accommodating cavity, and the ring body is connected to the second end by a connecting wire. The ring body is located between the first end and the second end, so that when the ring body is in the blood vessel, it can maintain the stability of its relative position through the connecting wire, thereby reducing the escape of thrombus in the accommodating cavity. BRIEF DESCRIPTION OF THE DRAWINGS

[0047] Figure 1 A schematic front view of a thrombus protector provided by an embodiment of the present invention; Figure 2 A schematic diagram of a thrombus protector provided in an embodiment of the present invention gradually pulling a containment cylinder with a traction wire; Figure 3 A schematic front view of a thrombus protector (with the seat body and the traction device hidden) provided in an embodiment of the present invention; Figure 4 for Figure 3 The enlarged schematic diagram at A in the middle; Figure 5 for Figure 3 Schematic diagram of the middle BB section; Figure 6 for Figure 5 Enlarged view of point C in the middle; Figure 7 for Figure 6 Schematic diagram of the middle containment cylinder; Figure 8 for Figure 5 Enlarged view of point D in the middle; Fig. 9 for Figure 5 Enlarged view of point E in the middle; Fig.10 A schematic diagram of the coordination of the net bag and the guide wire provided in an embodiment of the present invention; Fig.11 A schematic diagram of a guide rod provided in an embodiment of the present invention; Fig.12A three-dimensional schematic diagram (before the traction wire is pulled) of the thrombus protector provided by an embodiment of the present invention (the net bag is woven); Fig.13 A three-dimensional schematic diagram of a thrombus protector provided by an embodiment of the present invention (the traction wire is pulled for a certain distance) (the net bag is woven); Fig.14 A three-dimensional schematic diagram of a thrombus protector provided by an embodiment of the present invention (the traction wire is pulled a longer distance) (the net bag is woven); Fig.15 A three-dimensional schematic diagram (before the traction wire is pulled) of the thrombus protector provided by an embodiment of the present invention (the net bag is a thin film with holes); Fig.16 A three-dimensional schematic diagram of a thrombus protector provided by an embodiment of the present invention (the traction wire is pulled a certain distance) (the net bag is a thin film with holes); Fig.17 A schematic front view of a hypotube provided in an embodiment of the present invention; Fig.18 A schematic diagram of a y curve provided in an embodiment of the present invention.

[0048] Among them, the reference numerals in the figure are: 1-base; 21-net bag; 211-accommodating cavity; 22-containment tube; 221-first opening; 222-second opening; 3-guide rod; 31-hypotube; 311-first end; 312-spiral groove; 32-sleeve; 321-second end; 4-ring body; 41-thrombus entry channel; 5-connecting wire; 61-first ring; 62-second ring; 81-guide wire; 82-traction device; 83-traction wire; 9-thrombus. DETAILED DESCRIPTION

[0049] It should be noted that the specific embodiments are only used to explain the present invention, and are not used to limit the present invention.

[0050] It should be noted that, in the description of the embodiments of the present application, unless otherwise specified, " / " means or, for example, A / B can mean A or B; "and / or" in this article is only a description of the association relationship of associated objects, indicating that there can be three relationships, for example, A and / or B can mean: A exists alone, A and B exist at the same time, and B exists alone. Among them, A and B can be singular or plural respectively.

[0051] It should be noted that when an element is referred to as being "fixed on" or "set on" another element, it may be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" or "connected to" another element, it may be directly connected to the other element or indirectly connected to the other element. When an element is referred to as being "fixed on" or "set on" another element, it may be directly on the other element or indirectly on the other element.

[0052] It should be noted that the directions or positional relationships indicated by terms such as “length”, “width”, “up”, “down”, “front”, “back”, “left”, “right”, “vertical”, “horizontal”, “top”, “bottom”, “inside” and “outside” are based on the directions or positional relationships shown in the accompanying drawings and are only for the convenience of describing the present invention and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction. Therefore, they should not be understood as limiting the present invention.

[0053] It should be noted that the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features.

[0054] It should be noted that the term "plurality" means two or more than two, unless otherwise clearly and specifically defined.

[0055] Please also read Figures 1 to 17 The thrombus protector provided by the present invention is now described. The thrombus protector comprises: a seat body 1, a net bag 21, a guide rod 3, a ring body 4, and a connecting wire 5; the net bag 21 has a receiving cavity 211; the two ends of the guide rod 3 are respectively a first end 311 and a second end 321; the first end 311 is fixedly connected to the inner wall of the bottom of the receiving cavity 211; the second end 321 is connected to the seat body 1; the ring body 4 extends along the edge of the opening of the receiving cavity 211; the edge of the opening of the receiving cavity 211 is fixed on the ring body 4; the ring body 4 is sleeved on the outside of the guide rod 3; the ring body 4 can be bent and deformed under the action of external force; after the external force is removed, the ring body 4 can return to a ring shape; a thrombus entry channel 41 for the thrombus 9 to enter the receiving cavity 211 is formed between the ring body 4 and the guide rod 3; the connecting wire 5 connects the ring body 4 and the second end 321; the ring body 4 is located between the first end 311 and the second end 321.

[0056] In this way, the guide rod 3 is arranged on the seat body 1, and the two ends of the guide rod 3 are respectively a first end 311 and a second end 321, and the second end 321 is connected to the seat body 1, and the user can move the guide rod 3 by moving the seat body 1; the net bag 21 has a accommodating cavity 211, and when the user releases the net bag 21 in the blood vessel, the user can catch the thrombus 9 in the blood vessel through the accommodating cavity 211; the edge of the opening of the accommodating cavity 211 is fixed with a ring body 4, and the ring body 4 extends along the edge of the opening of the accommodating cavity 211, so that the ring body 4 can support the edge of the opening of the accommodating cavity 211; under the action of external force, the ring body 4 can bend and deform, so that the ring body 4 It can be folded and stored under the action of external force, which is convenient for folding and storing the net bag 21; when the ring body 4 is released into the blood vessel, the ring body 4 can restore its ring shape to open the opening of the accommodating cavity 211, and the thrombus 9 can enter the accommodating cavity 211 more easily from the opening of the accommodating cavity 211; the first end 311 of the guide rod 3 is fixedly connected to the inner wall of the bottom of the accommodating cavity 211, and the ring body 4 is connected to the second end 321 through the connecting wire 5. The ring body 4 is located between the first end 311 and the second end 321, so that when the ring body 4 is in the blood vessel, it can maintain the stability of its relative position through the connecting wire 5, thereby reducing the escape of thrombus in the accommodating cavity 211.

[0057] In one embodiment, regarding: "net bag 21": [1] The term "net bag 21" refers to a bag-like structure made of a mesh material (such as fiber, metal wire or plastic), which is usually used to hold, capture or wrap objects. The design feature of the net bag 21 is that it has a certain elasticity or stretchability, which can accommodate objects and allow them to pass through liquids, air or flow, while effectively keeping the objects in the net bag 21 from being easily lost or scattered. The net bag 21 is widely used in many fields, including medical treatment, sports, daily life, etc. [2] The first example: a thrombus 9 catching net bag 21 in the medical field: In medical devices, the net bag 21 is often used in a thrombus 9 catching catheter. The doctor introduces a device with a net bag 21 into the blood vessel through a catheter. The function of the net bag 21 is to capture the thrombus 9 or other obstructions in the blood vessel. This net bag 21 is designed to be sufficiently elastic to capture the thrombus 9.

[0058] In one embodiment, the net bag 21 is foldable and / or bendable.

[0059] For further information, see Figures 1 to 17As a specific embodiment of the thrombus protector provided by the present invention, the ring body 4 is: a memory alloy ring or an elastic ring. Thus, regarding the memory alloy ring: the memory alloy material (such as NiTi alloy) can restore the preset shape at the temperature inside the human blood vessel, which enables the net bag 21 to adapt to the blood vessel environment and effectively unfold. Regarding the elastic ring: the flexibility and elasticity of the elastic ring enable the net bag 21 to unfold more smoothly in narrow blood vessels, while causing less stimulation to the blood vessels and reducing damage to the blood vessel walls. The elastic ring can also effectively withstand pressure changes inside the blood vessels, maintain the stability of the net bag 21, and ensure that the net bag 21 can be firmly fixed when capturing the thrombus 9.

[0060] In one embodiment, the elastic ring is silicone or rubber.

[0061] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the ring body 4 is a nickel-titanium alloy ring. Thus, nickel-titanium alloy (NiTi) is a material with excellent shape memory effect. When the nickel-titanium alloy ring is exposed in a blood vessel, it can automatically return to a predetermined shape. In the blood vessel, as the body temperature changes, the nickel-titanium alloy ring can self-regulate and quickly unfold, thereby ensuring that the net bag 21 can be quickly and accurately positioned in the blood vessel.

[0062] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the connecting wire 5 is a memory alloy wire. In this way, the memory alloy material (such as NiTi alloy) can restore the preset shape at the temperature in the human blood vessel.

[0063] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the connecting wire 5 is a nickel-titanium alloy wire. Thus, the nickel-titanium alloy has extremely high strength and corrosion resistance, and can maintain its structural integrity when used in a blood vessel for a long time, and is not prone to deformation or corrosion.

[0064] For further information, see Figures 1 to 17As a specific embodiment of the thrombus protector provided by the present invention, the ring body 4 and the net bag 21 are connected by any one of welding, wire winding, knitting, and bonding. In this way, regarding welding: the welding connection can provide a higher mechanical strength, which can ensure that the connection between the ring body 4 and the net bag 21 is very stable, and avoid falling off due to external force when capturing the thrombus 9. Regarding wire winding: the wire winding connection can form a stable connection by winding a filament material (such as stainless steel wire or polymer wire) between the net bag 21 and the ring body 4. This method has a certain flexibility, which can ensure the flexibility of the net bag 21 when it is unfolded and adapt to the complex structure and pressure changes in the blood vessel. The wire winding connection can also enhance the tensile strength between the net bag 21 and the ring body 4 and improve the reliability of the device. Regarding knitting: knitting connection is usually used for softer materials, such as polymer net bags 21. Through the knitting process, the ring body 4 and the net bag 21 are connected in a woven manner, which has good elasticity and adaptability, and is suitable for fine-tuning the thrombus 9 during the capture process to avoid excessive tension and damage to the blood vessel. Knitted connection can provide higher flexibility and wear resistance, and is suitable for thrombus 9 capture that requires flexibility and high stretchability. About bonding: Bonding is to connect the net bag 21 to the ring body 4 by using a strong adhesive, which is suitable for precise design, especially when it involves the combination of different materials. The bonding connection method can avoid the abrupt seams caused by traditional mechanical connections, provide a smoother structural transition, and reduce friction or damage to blood vessels. Bonding can also ensure a tight connection between the net bag 21 and the ring body 4 without adding extra weight.

[0065] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, there are multiple connecting wires 5. In this way, multiple connecting wires 5 can improve the stability of the position of the ring body 4 itself.

[0066] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the number of connecting wires 5 is two. In this way, the connecting wires 5 can maintain the stability of the ring body 4 at two positions.

[0067] For further information, see Figures 1 to 17As a specific embodiment of the thrombus protector provided by the present invention, a support space is formed between multiple connecting wires 5; the support space is connected to the accommodating cavity 211; the external space is connected to the support space through the gap between any adjacent connecting wires 5. In this way, the support space formed between the multiple connecting wires 5; the connection between the support space and the accommodating cavity 211 ensures that the net bag 21 can flexibly adapt to thrombi 9 of different sizes and shapes. The external space is connected to the support space through the gap between any adjacent connecting wires 5, so that the blood flow is not subject to excessive resistance. Blood can flow through these gaps, avoiding the situation where the net bag 21 obstructs blood flow, while also reducing the pressure on the inner wall of the blood vessel, providing higher biocompatibility and safety.

[0068] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the cross section of the support space gradually narrows along the extension direction of the guide rod 3 from the first end 311 to the second end 321. In this way, the design of the gradually narrowing cross section of the support space allows the net bag 21 to gradually shrink or expand in the guide rod 3 according to the size and position of the blood vessel. The gradually narrowing cross section of the support space can also optimize the blood flow path and reduce the obstruction of the net bag 21 to the blood flow.

[0069] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the net bag 21 is: a metal woven mesh; or the net bag 21 is: a porous polymer molding mesh. In this way, the metal woven mesh has excellent mechanical strength and elasticity, so that it can withstand high tension and pressure and adapt to the expansion and contraction in a complex vascular environment. The polymer molding mesh can customize the shape and aperture of the net bag 21 through the formable characteristics of the plastic material to adapt to different types of thrombi 9. The perforated design can not only provide a better capture effect, but also ensure the fluidity of blood while reducing the mass of the net bag 21.

[0070] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the net bag 21 is: a nickel-titanium wire braided mesh. In this way, the net bag 21 is braided with nickel-titanium wires, can be automatically unfolded in the blood vessel, and maintain the stability and shape of the net bag 21.

[0071] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, it also includes: a first ring 61 sleeved and fixed on the first end 311; the first ring 61 is made of any material selected from platinum, platinum-iridium alloy, and gold. In this way, the first ring 61 can serve as a developing ring.

[0072] For further information, see Figures 1 to 17As a specific embodiment of the thrombus protector provided by the present invention, the connection between the net bag 21 and the first end 311 is clamped between the first ring 61 and the first end 311. In this way, the first end 311 of the net bag 21 is more stable under the clamping of the first ring 61.

[0073] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, it also includes: a second ring 62 sleeved and fixed on the second end 321; the second ring 62 is made of any one of platinum, platinum-iridium alloy, and gold. In this way, the second ring 62 can serve as a developing ring.

[0074] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, it also includes: a guide wire 81; one end of the guide wire 81 is connected to the first end 311; and the other end of the guide wire 81 is located outside the net bag 21. In this way, the guide wire 81 can play a guiding role.

[0075] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, it also includes: a blocking tube 22, a traction wire 83, and a traction device 82 arranged on the seat body 1; the two end openings of the blocking tube 22 are respectively a first opening 221 and a second opening 222; the edge of the first opening 221 is fixed on the ring body 4, and the ring body 4 extends along the edge of the first opening 221; the traction device 82 is connected to the edge of the second opening 222 through the traction wire 83, and the traction wire 83 can pull the edge of the second opening 222 in a direction away from the first end 311 to sleeve the blocking tube 22 on the outside of the connecting wire 5. In this way, after the traction wire 83 pulls the edge of the second opening 222 in a direction away from the first end 311, the blocking tube 22 can be sleeved on the outside of the connecting wire 5, and the blocking tube 22 can be blocked on the outside of the opening of the accommodating cavity 211, reducing the thrombus 9 in the accommodating cavity 211 from falling off and escaping again or being brought to other areas. During the intravascular treatment process, the containment tube 22 can adjust the position of the containment tube 22 through the traction effect with the ring body 4 and make the containment tube 22 firmly cover the thrombus 9, thereby ensuring the treatment effect.

[0076] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the containment tube 22 can be folded and sleeved on the outer wall of the net bag 21. In this way, the containment tube 22 can be stored outside the net bag 21 to save space.

[0077] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the containment tube 22 is an integral piece made of elastic material. In this way, the containment tube 22 can change its shape to adapt to the environment in the blood vessel.

[0078] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the containment tube 22 is made of any one of the following materials: nylon, pebax (pebax: block polyetheramide resin), and polyester film by blow molding. In this way, nylon, as a wear-resistant and high-strength material, can withstand high pressure and traction in the blood vessels, ensuring that the containment tube 22 is not easy to break or damage during the treatment process. Pebax, as a material with excellent elasticity and durability, can maintain long-term stability in the blood vessels. Polyester film has strong tensile strength and high heat resistance, which can ensure that the containment tube 22 maintains its shape unchanged in a complex vascular environment.

[0079] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, a plurality of through holes are provided on the containment tube 22. In this way, blood can flow through the through holes.

[0080] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the tractor 82 includes: a toggle switch; the toggle switch is slidably arranged on the seat body 1; one end of the traction wire 83 is connected to the toggle switch, and the other end of the traction wire 83 is connected to the edge of the second opening 222 of the containment tube 22. In this way, the toggle switch can pull the containment tube 22 to move through the traction wire 83.

[0081] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the traction wire 83 can be made of any one of nickel-titanium, stainless steel, and nylon ribbon wire. In this way, nickel-titanium alloy (memory alloy) has excellent shape memory effect and elasticity. Stainless steel, as a high-strength, corrosion-resistant material, has excellent tensile strength and toughness. Nylon ribbon wire has good flexibility and biocompatibility.

[0082] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the guide rod 3 has a wire entry channel, and the traction wire 83 passes through the wire entry channel and is connected to the toggle switch. In this way, the traction wire 83 can be stored in the wire entry channel.

[0083] For further information, see Figures 1 to 17As a specific embodiment of the thrombus protector provided by the present invention, the guide rod 3 includes: a hypotube 31 (hypotube 31: Hibiscus Tube) and a sleeve 32; the hypotube 31 and the sleeve 32 are respectively connected to the seat body 1; one end of the hypotube 31 is a first end 311, and the sleeve 32 is sleeved on the other end of the hypotube 31; the end of the sleeve 32 close to the first end 311 is a second end 321; a wire feeding channel is formed between the sleeve 32 and the hypotube 31. In this way, the sleeve 32 can protect the internal hypotube 31, and the hypotube 31 is prone to deformation.

[0084] In one embodiment, the hypotube 31 is made of a polymer material (such as polyurethane (PU), polyamide (nylon), polytetrafluoroethylene (PTFE), PEBAX, etc.). These materials have good flexibility, corrosion resistance and biocompatibility, and can ensure long-term use in blood vessels without causing tissue irritation or allergic reactions. In one embodiment, the hypotube 31 is made of materials such as stainless steel or nickel-titanium alloy to enhance its strength and stability. These metal materials can provide higher tensile strength to help the catheter maintain its shape and withstand external pressure during operation.

[0085] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the outer surface of the hypotube 31 has a spiral groove 312 formed by laser processing. In this way, the spiral groove 312 can improve the bending ability of the hypotube 31.

[0086] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, it also includes: an ultrasonic generator arranged on the seat body 1, and the ultrasonic generator is connected to the guide rod 3. In this way, the ultrasonic wave is transmitted to the guide rod 3, and the ultrasonic wave guided is transmitted to the net bag 21, thereby reducing the adhesion of the thrombus 9 to the net bag 21.

[0087] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, it also includes: a medicine bag containing a thrombolytic drug disposed in the accommodating cavity 211. In this way, the thrombus 9 in the accommodating cavity 211 can be dissolved after the thrombus 9 in the accommodating cavity 211 is released.

[0088] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the medicine bag has an opening; the opening is covered with a protective cover; the protective cover is rotatably arranged on the medicine bag; the protective cover is connected to a pulling line for pulling and opening the protective cover. In this way, after the user opens the protective cover by pulling the line, the medicine can be discharged into the accommodating cavity 211 through the opening.

[0089] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, a mesh is laid on the inner wall of the accommodating cavity 211; the mesh is fixedly connected to the inner wall of the accommodating cavity 211 by a plurality of fasteners. In this way, the mesh can provide sequential filtration for the blood in the accommodating cavity 211, and the net bag 21 can provide a second filtration, and the mesh and the net bag 21 can together improve the interception capability of the thrombus 9.

[0090] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the mesh holes on the mesh body are smaller than the mesh holes on the net bag 21. In this way, the ability of the mesh body inside the net bag 21 to intercept thrombi 9 is greater than that of the net bag 21 to intercept thrombi 9, so that thinner thrombi 9 can be caught by the mesh body inside the net bag 21, reducing the possibility of thrombi 9 leaking from the net bag 21.

[0091] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the mesh body is spaced apart from the inner wall of the accommodating cavity 211. In this way, when blood is filtered through the mesh body and the net bag 21 in sequence, the thrombus 9 adhered to the mesh body is not easy to adhere to the inner wall of the accommodating cavity 211, thereby reducing the thrombus 9 from blocking the mesh body and the net bag 21 at the same time.

[0092] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the mesh holes on the mesh body and the mesh holes on the net bag 21 are arranged alternately. In this way, part of the thrombus 9 can be easily intercepted by the net bag 21 when passing through the mesh holes on the mesh body.

[0093] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the inner wall of the net bag 21 is covered with a thrombolytic drug coating for reducing the formation of thrombus 9. In this way, when blood remains in the net bag 21, the thrombolytic drug can reduce the formation of thrombus 9 in the net bag 21.

[0094] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, any adjacent grids on the net bag 21 are rotatably connected to each other. In this way, the adjacent grids of the net bag 21 can rotate with each other to change the relative position, and the relative rotation of the adjacent grids can change the shape of the net bag 21.

[0095] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, it also includes: a universal coupling structure; any adjacent grids on the net bag 21 are rotatably connected by the universal coupling structure. In this way, the adjacent grids can be relatively rotated very conveniently through the universal coupling structure.

[0096] In one embodiment, the universal coupling structure is: a universal coupling.

[0097] For further information, see Fig.18 As a specific embodiment of the thrombus protector provided by the present invention, when the guide rod 3 extends along the x-axis and the net bag 21 is opened, in the axial section passing through the axis of the guide rod 3 and arranged vertically, the trajectory of the outer wall of the net bag 21 on one side of the x-axis is parallel to y=0.0001*x^3 +0.01*x^2−0.5*x (where -85≤x≤19), and the trajectories of the outer walls of the net bag 21 on both sides of the guide rod 3 are axisymmetric (in one embodiment, the trajectories of the outer walls of the net bag 21 on both sides of the guide rod 3 are symmetrically arranged on both sides of the x-axis. In one embodiment, the axis of the guide rod 3 is the x-axis. In one embodiment, the x-axis is the symmetry axis of the guide rod 3.). In this way, when -85≤x≤19, the trajectory of y is between the peak value H1 on the left side of the Y-axis and the valley value H2 on the right side of the Y-axis. [1] Smooth curve characteristics: The cubic term (x^3) and the square term (x^2) make the side wall present a smooth and continuous change without sharp inflection points or irregular mutations. This is very important for the deployment of the net bag 21, because the smooth curve can ensure that the net bag 21 is evenly deployed in the blood vessel, avoiding excessive pressure on the blood vessel wall caused by the mutation point, and reducing damage to the blood vessel. [2] Bending characteristics: The combination of the "negative first-order term (-0.5x)" and other terms affects the inclination of the curve. The curve gradually bends downward when the x value is between H1 and H2, which indicates that the side wall of the net bag 21 gradually shrinks within a certain range. This design may be used to adapt to the curvature changes of different blood vessels. This change characteristic of the side wall of the net bag 21 ensures its adaptability in complex blood vessel structures and can be adjusted as the morphology of the blood vessel changes. [3] Adaptation to complex blood vessels: The change of the curve allows the side wall of the net bag 21 to be flexibly adjusted according to the size, shape and blood flow speed of the blood vessel. When the curve in the blood vessel changes greatly, the side wall of the net bag 21 can effectively adapt to the complex environment of the blood vessel through this nonlinear change, ensuring that the thrombus 9 is firmly wrapped.

[0098] In one embodiment, the containment tube 22 and the net bag 21 are connected by welding, winding wire knitting and bonding.

[0099] In one embodiment, the first ring 61 is a circular ring.

[0100] In one embodiment, the second ring 62 is a circular ring.

[0101] In one embodiment, the metal braided or polymer-molded net bag 21 has a self-expanding function and can automatically expand and fit the inner wall of the blood vessel after being transported out of the mouth of the carrier catheter.

[0102] In one embodiment, the connecting wire 5 is a memory alloy support wire. The memory alloy support wire is used to support the containment tube 22, so that it can maintain the gourd shape when the containment tube 22 is released. Its material is the same as the memory alloy support ring (i.e., the ring body 4) at the mouth of the net bag 21. In one embodiment, the connecting wire 5 can be connected to the sleeve 32 by riveting / welding / bonding / inlaying. In one embodiment, the connecting wire 5 can be connected to the ring body 4 by riveting / welding / bonding / inlaying.

[0103] In one embodiment, the connecting wire 5 is arched toward the outside.

[0104] In one embodiment, the connecting wire 5 is partially connected to the net bag 21 smoothly.

[0105] In one embodiment, the sleeve 32 is a bendable metal tube.

[0106] In one embodiment, the sea wave tube 31 is inside the entire protector net bag 21 and is in a spiral hollow shape. This structure can be achieved by laser cutting to provide compliance for the protector net bag 21. The distal end of the inner sea wave tube 31 is connected to the first ring 61 and the head end of the net bag 21 by riveting / welding / bonding / inlaying.

[0107] In one embodiment, the guide wire 81 is made of winding wire or soft elastomeric material, and plays a guiding role. The guide wire 81 is connected to the inner layer hypotube 31 by riveting / welding / bonding / inserting. In one embodiment, the guide wire 81 is connected to the first ring 61 by riveting / welding / bonding / inserting.

[0108] In one embodiment, the seat body 1 is made of polycarbonate or polyethylene material.

[0109] In one embodiment, the tractor 82 is a button, which is made of polycarbonate, polyethylene or metal.

[0110] In one embodiment, the traction wire 83 is connected to the first ring 61 by bonding / welding, inlaying, etc. In one embodiment, the traction wire 83 is connected to the tractor 82 by bonding / welding, inlaying, etc.

[0111] In one embodiment, the sleeve 32 is a hollow structure made of metal materials such as stainless steel or nickel titanium tube.

[0112] In one embodiment, the distal end of the net bag 21 is connected to the guide wire 81 , and the metal braided or polymer-molded net bag 21 is connected to the hypotube 31 .

[0113] See also Figures 1 to 17The present invention also provides a thrombus protection catheter, including: a tube body and a thrombus protector; the tube body has a tube cavity, and the net bag 21 is accommodated in the tube body. In this way, the net bag 21 can be accommodated in the tube cavity first, and after the tube body is removed, the net bag 21 can be exposed in the blood vessel; due to the use of the above-mentioned thrombus protector, the guide rod 3 is arranged on the seat body 1, and the two ends of the guide rod 3 are respectively a first end 311 and a second end 321, and the second end 321 is connected to the seat body 1, and the user can move the guide rod 3 by moving the seat body 1; the net bag 21 has a receiving cavity 211, and when the user releases the net bag 21 in the blood vessel, the user can catch the thrombus 9 in the blood vessel through the receiving cavity 211; a ring body 4 is fixed to the edge of the opening of the receiving cavity 211, and the ring body 4 extends along the edge of the opening of the receiving cavity 211, so that the ring body 4 can support the edge of the opening of the receiving cavity 211. Use; under the action of external force, the ring body 4 can bend and deform, so that the ring body 4 can be folded and stored under the action of external force, which is convenient for the folding and storage of the net bag 21; when the ring body 4 is released into the blood vessel, the ring body 4 can restore its ring shape to open the opening of the accommodating cavity 211, and the thrombus 9 can more easily enter the accommodating cavity 211 from the opening of the accommodating cavity 211; the first end 311 of the guide rod 3 is fixedly connected to the inner wall of the bottom of the accommodating cavity 211, and the ring body 4 is connected to the second end 321 through the connecting wire 5. The ring body 4 is located between the first end 311 and the second end 321, so that when the ring body 4 is in the blood vessel, it can maintain the stability of its relative position through the connecting wire 5, thereby reducing the escape of thrombus in the accommodating cavity 211.

[0114] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and substitutions can be made without departing from the technical principles of the present invention. These improvements and substitutions should also be regarded as the scope of protection of the present invention.

Claims

1. A thrombus protector, characterized in that: include: seat body; Net bag; The net bag has a receiving cavity; A guide rod; the two ends of the guide rod are respectively a first end and a second end; the first end is fixedly connected to the inner wall of the bottom of the accommodating cavity; the second end is connected to the seat body; A ring body; the ring body extends along the edge of the opening of the accommodating cavity; the edge of the opening of the accommodating cavity is fixed on the ring body; the ring body is sleeved on the outside of the guide rod; the ring body can be bent and deformed under the action of external force; after the external force is removed, the ring body can return to a ring shape; a thrombus entry channel for allowing thrombus to enter the accommodating cavity is formed between the ring body and the guide rod; Connecting wire; The connecting wire connects the ring body and the second end; the ring body is located between the first end and the second end.

2. The thrombus protector according to claim 1, characterized in that: The number of the connecting wires is multiple.

3. The thrombus protector according to claim 2, characterized in that: The number of the connecting wires is two.

4. The thrombus protector according to claim 2, characterized in that: A supporting space is formed between the plurality of connecting wires; the supporting space is communicated with the accommodating cavity; and the external space is communicated with the supporting space through the gaps between any adjacent connecting wires.

5. The thrombus protector according to claim 4, characterized in that: Along the extension direction of the guide rod from the first end to the second end, the cross section of the support space gradually narrows.

6. The thrombus protector according to claim 1, characterized in that: Also includes: Guidewire; One end of the guide wire is connected to the first end; the other end of the guide wire is located outside the net bag.

7. The thrombus protector according to any one of claims 1 to 6, characterized in that: Also includes: A containment cylinder, a traction wire, and a tractor arranged on the seat body; the openings at both ends of the containment cylinder are respectively a first opening and a second opening; The edge of the first opening is fixed on the ring body, and the ring body extends along the edge of the first opening; the traction device is connected to the edge of the second opening through the traction wire, and the traction wire can pull the edge of the second opening away from the first end to sleeve the containment cylinder on the outside of the connecting wire.

8. The thrombus protector according to claim 7, characterized in that: The containment cylinder can be folded and sleeved on the outer wall of the net bag.

9. The thrombus protector according to claim 7, characterized in that: The containment cylinder is an integral piece made of elastic material.

10. The thrombus protector according to claim 7, characterized in that: The traction device comprises: a toggle switch; the toggle switch is slidably arranged on the seat body; one end of the traction wire is connected to the toggle switch, and the other end of the traction wire is connected to the second opening edge of the containment cylinder.

11. The thrombus protector according to claim 10, characterized in that: The guide rod is provided with a wire feeding channel, and the traction wire passes through the wire feeding channel and is connected to the toggle switch.

12. The thrombus protector according to claim 11, characterized in that: The guide rod includes: a hypotube and a sleeve; the hypotube and the sleeve are respectively connected to the seat body; one end of the hypotube is the first end, and the sleeve is sleeved on the other end of the hypotube; the end of the sleeve close to the first end is the second end; the wire feeding channel is formed between the sleeve and the hypotube.

13. The thrombus protector according to any one of claims 1 to 6, characterized in that: A mesh is laid on the inner wall of the accommodating cavity; the mesh is fixedly connected to the inner wall of the accommodating cavity by a plurality of fasteners.

14. The thrombus protector according to any one of claims 1 to 6, characterized in that: Any adjacent grids on the net bag are rotatably connected to each other.

15. The thrombus protector according to any one of claims 1 to 6, characterized in that: When the guide rod extends along the x-axis and the net bag is opened, in an axial section passing through the axis of the guide rod and vertically arranged, the trajectory of the outer wall of the net bag on one side of the x-axis is parallel to y=0.0001*x^3 +0.01*x^2−0.5*x (wherein, -85≤x≤19), and the trajectories of the outer walls of the net bag on both sides of the guide rod are axially symmetrical.

16. An embolic protection catheter, characterized in that: include: A tube body and a thrombus protector as claimed in any one of claims 1 to 15; the tube body has a lumen, and the net bag is received in the lumen.

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