A thrombus protector and a thrombus protection catheter

Abstract

The present invention relates to the technical field of catheter medical devices, and provides a thrombus protector and a thrombus protection catheter, comprising: a seat body; a mesh pocket, a guide rod, a ring body, and connecting wires; the mesh pocket has a receiving cavity; the two ends of the guide rod are respectively a first end and a second end; the first end is fixedly connected to the inner wall of the bottom of the receiving cavity; the second end is connected to the seat body; the ring body extends along the edge of the opening of the receiving cavity; the edge of the opening of the receiving cavity is fixed on the ring body; the ring body is sleeved outside the guide rod; the ring body can be bent and deformed under an external force; after the external force is removed, the ring body can recover to be in a ring shape; a thrombus inlet channel for allowing thrombus to enter the receiving cavity is formed between the ring body and the guide rod; the connecting wires connect the ring body and the second end; the ring body is located between the first end and the second end.

Description

Technical Field

[0001] The present invention belongs to the technical field of catheter medical devices, and more specifically, relates to a thrombus protector and a thrombus protection catheter. Background Art

[0002] Ischemic stroke, also known as cerebral infarction, refers to the blockage or severe stenosis of cerebral blood vessels caused by cerebral blood circulation disorders, resulting in reduced cerebral blood flow or insufficient cerebral oxygen supply, causing death of brain tissue in the cerebral blood supply area. Approximately 20%-30% of strokes are related to atherosclerotic carotid artery stenosis. The main surgical methods for treating carotid artery stenosis include carotid endarterectomy (CEA) and carotid artery stenting (CAS). In carotid artery stenting, a distal embolization protection device can effectively reduce the incidence of embolism events caused by the shedding of emboli. A thrombus removal protection device (hereinafter referred to as an embolization protection device) is used to completely remove emboli. This type of device has the advantage of being able to remove thrombi without interrupting blood flow and can be used for most patients.

[0003] Lower extremity arterial disease refers to a disease of local ischemia of the body caused by local stenosis or occlusion of the lower extremity arteries. The main cause is atherosclerosis, and atherosclerotic-related lesions account for 90%-95% of all lesions. In lower extremity arterial disease, distal embolization protection devices are mainly used in volume reduction treatments such as removing plaques or thrombi to reduce the incidence of distal embolization events.

[0004] Both of the above two diseases use distal embolization protection devices (thrombus protectors). Due to the structural defects of the mesh bag in similar devices on the market, there will still be a situation where the captured emboli escape after capturing thrombus debris. Summary of the Invention

[0005] The purpose of the present invention is to provide a thrombus protector to solve the technical problem of easy escape of thrombus during capture in the prior art.

[0006] To achieve the above purpose, the technical solution adopted by the present invention is: providing a thrombus protector, including:

[0007] A seat body;

[0008] A mesh bag; the mesh bag has a receiving cavity;

[0009] A guide rod; the two ends of the guide rod are respectively a first end and a second end; the first end is fixedly connected to the inner wall of the bottom of the receiving cavity; the second end is connected to the seat body;

[0010] Ring body; the ring body extends along the edge of the opening of the accommodating cavity; the edge of the opening of the accommodating cavity is fixed on the ring body; the ring body is sleeved outside the guide rod; the ring body can be bent and deformed under the action of an external force; after the external force is removed, the ring body can return to a ring shape; an embolism inlet channel for allowing a thrombus to enter the accommodating cavity is formed between the ring body and the guide rod;

[0011] Connecting wire; the connecting wire connects the ring body and the second end; the ring body is located between the first end and the second end.

[0012] Further, the ring body is: a shape memory alloy ring or an elastic ring.

[0013] Further, the ring body is: a nitinol alloy ring.

[0014] Further, the connecting wire is: a shape memory alloy wire.

[0015] Further, the connecting wire is: a nitinol alloy wire.

[0016] Further, the ring body and the mesh bag are connected by any one of welding, wire winding, knitting, and bonding.

[0017] Further, the number of the connecting wires is multiple.

[0018] Further, the number of the connecting wires is two.

[0019] Further, a support space is formed between multiple connecting wires; the support space is communicated with the accommodating cavity; the external space is communicated with the support space through the gap between any adjacent connecting wires.

[0020] Further, along the extending direction of the guide rod from the first end to the second end, the cross section of the support space gradually narrows.

[0021] Further, the mesh bag is: a metal braided mesh; or the mesh bag is: a perforated polymer plastic mesh.

[0022] Further, the mesh bag is: a nitinol wire braided mesh.

[0023] Further, it further includes: a first ring sleeved and fixed on the first end.

[0024] Further, the connection part of the mesh bag with the first end is clamped between the first ring and the first end.

[0025] Further, the first ring is made of any one of platinum, platinum-iridium alloy, and gold.

[0026] Furthermore, it also includes: a second ring sleeved and fixed on the second end.

[0027] Furthermore, the second ring is made of any one of platinum, platinum-iridium alloy, and gold.

[0028] Furthermore, it also includes: a guide wire; one end of the guide wire is connected to the first end; and the other end of the guide wire is located outside the net bag.

[0029] Furthermore, it also includes: a containment tube, a traction wire, and a traction device arranged on the seat body; the openings at both ends of the containment tube are respectively a first opening and a second opening; the edge of the first opening is fixed on the ring body, and the ring body extends along the edge of the first opening; the traction device is connected to the edge of the second opening through the traction wire, and the traction wire can pull the edge of the second opening in a direction away from the first end to sleeve the containment tube on the outside of the connecting wire.

[0030] Furthermore, the containment cylinder can be folded and sleeved on the outer wall of the net bag.

[0031] Furthermore, the containment cylinder is an integral piece made of elastic material.

[0032] Furthermore, the containment cylinder is made of any one of nylon, pebax, and polyester film by blow molding.

[0033] Furthermore, the containment cylinder is provided with a plurality of through holes.

[0034] Furthermore, the traction device includes: a toggle switch; the toggle switch is slidably mounted on the seat; one end of the traction wire is connected to the toggle switch, and the other end of the traction wire is connected to the second opening edge of the containment cylinder.

[0035] Furthermore, the traction wire can be made of any one of nickel-titanium, stainless steel, and nylon ribbon wire.

[0036] Furthermore, a wire feeding channel is provided in the guide rod, and the traction wire passes through the wire feeding channel and is connected to the toggle switch.

[0037] Further, the guide rod includes: a hypotube and a sleeve; the hypotube and the sleeve are respectively connected to the seat body; one end of the hypotube is the first end, and the sleeve is sleeved on the other end of the hypotube; the end of the sleeve close to the first end is the second end; the wire feeding channel is formed between the sleeve and the hypotube.

[0038] Furthermore, the outer surface of the hypotube has a spiral groove formed by laser processing.

[0039] Further, it further includes: an ultrasonic generator disposed on the seat body, and the ultrasonic generator is connected to the guide rod.

[0040] Further, it further includes: a medicine bag containing a thrombolytic drug and disposed in the accommodation cavity.

[0041] Further, the medicine bag has an opening; a protective cover is covered on the opening; the protective cover is rotatably disposed on the medicine bag; a pulling wire for pulling and opening the protective cover is connected to the protective cover.

[0042] Further, a mesh body is laid on the inner wall of the accommodation cavity; the mesh body is fixedly connected to the inner wall of the accommodation cavity through a plurality of fasteners.

[0043] Further, the mesh holes on the mesh body are smaller than the mesh holes on the mesh pocket.

[0044] Further, a gap is provided between the mesh body and the inner wall of the accommodation cavity.

[0045] Further, the mesh holes on the mesh body and the mesh holes on the mesh pocket are arranged in a staggered manner.

[0046] Further, a thrombolytic drug coating for reducing thrombus formation is covered on the inner wall of the mesh pocket.

[0047] Further, any two adjacent meshes on the mesh pocket are rotatably connected to each other.

[0048] Further, it further includes: a universal coupling structure; any two adjacent meshes on the mesh pocket are respectively rotatably connected through the universal coupling structure.

[0049] Further, when the guide rod extends along the x-axis and after the mesh pocket is opened, in the axial section passing through the axis of the guide rod and vertically arranged, the trajectory of the outer wall of the mesh pocket on one side of the x-axis is parallel to y = 0.0001*x^3 + 0.01*x^2 - 0.5*x (where -85 ≤ x ≤ 19), and the trajectories of the outer walls of the mesh pocket on both sides of the guide rod are axisymmetric.

[0050] The present invention also provides a thrombus protection catheter, including: a catheter body and the thrombus protector; the catheter body has a lumen, and the mesh pocket is received in the catheter body.

[0051] The beneficial effects of the thrombus protector provided by the present invention are as follows: Compared with the prior art, for the thrombus protector provided by the present invention, the guiding rod is arranged on the seat body. The two ends of the guiding rod are respectively the first end and the second end, and the second end is connected to the seat body. The user can move the guiding rod by moving the seat body; the mesh bag has a receiving cavity. When the user releases the mesh bag into the blood vessel, the user can trap the thrombus in the blood vessel through the receiving cavity; a ring body is fixed at the edge of the opening of the receiving cavity, and the ring body extends along the edge of the opening of the receiving cavity, so that the ring body can support the edge of the opening of the receiving cavity; under an external force, the ring body can be bent and deformed, so that the ring body can be folded and stored under the action of the external force, which is convenient for the folding and storage of the mesh bag; when the ring body is released into the blood vessel, the ring body can return to a ring shape to open the opening of the receiving cavity, and the thrombus can more easily enter the receiving cavity through the opening of the receiving cavity; the first end of the guiding rod is fixedly connected to the inner wall of the bottom of the receiving cavity, and the ring body is connected to the second end through a connecting wire. The ring body is located between the first end and the second end, so that the ring body can maintain the stability of its relative position through the connecting wire when in the blood vessel, reducing the escape of thrombus in the receiving cavity. BRIEF DESCRIPTION OF THE DRAWINGS

[0052] Figure 1 is the front view schematic diagram of the thrombus protector provided by the embodiment of the present invention;

[0053] Figure 2 is the schematic diagram of the traction wire of the thrombus protector provided by the embodiment of the present invention gradually pulling and blocking the cylinder;

[0054] Figure 3 is the front view schematic diagram of the thrombus protector (hiding the seat body and the tractor) provided by the embodiment of the present invention;

[0055] Figure 4 is Figure 3 the enlarged schematic diagram at A in

[0056] Figure 5 is Figure 3 the sectional view along B-B in

[0057] Figure 6 is Figure 5 the enlarged view at C in

[0058] Figure 7 is Figure 6 the schematic diagram of the blocking cylinder in

[0059] Figure 8 is Figure 5 the enlarged view at D in

[0060] Figure 9 is Figure 5 the enlarged view at E in

[0061] Figure 10A schematic diagram of the coordination of the net bag and the guide wire provided in an embodiment of the present invention;

[0062] Figure 11 A schematic diagram of a guide rod provided in an embodiment of the present invention;

[0063] Figure 12 A three-dimensional schematic diagram (before the traction wire is pulled) of the thrombus protector provided by an embodiment of the present invention (the net bag is woven);

[0064] Figure 13 A three-dimensional schematic diagram of a thrombus protector provided by an embodiment of the present invention (the traction wire is pulled for a certain distance) (the net bag is woven);

[0065] Figure 14 A three-dimensional schematic diagram of a thrombus protector provided by an embodiment of the present invention (the traction wire is pulled a longer distance) (the net bag is woven);

[0066] Figure 15 A three-dimensional schematic diagram (before the traction wire is pulled) of the thrombus protector provided by an embodiment of the present invention (the net bag is a thin film with holes);

[0067] Figure 16 A three-dimensional schematic diagram of a thrombus protector provided by an embodiment of the present invention (the traction wire is pulled a certain distance) (the net bag is a thin film with holes);

[0068] Figure 17 A schematic front view of a hypotube provided in an embodiment of the present invention;

[0069] Figure 18 A schematic diagram of a y curve provided in an embodiment of the present invention.

[0070] Among them, the reference numerals in the figure are:

[0071] 1-base; 21-net bag; 211-accommodating cavity; 22-containment tube; 221-first opening; 222-second opening; 3-guide rod; 31-hypotube; 311-first end; 312-spiral groove; 32-sleeve; 321-second end; 4-ring body; 41-thrombus entry channel; 5-connecting wire; 61-first ring; 62-second ring; 81-guide wire; 82-traction device; 83-traction wire; 9-thrombus. DETAILED DESCRIPTION

[0072] It should be noted that the specific embodiments are only used to explain the present invention, and are not used to limit the present invention.

[0073] It should be noted that in the description of the embodiments of the present application, unless otherwise specified, " / " means "or". For example, A / B may mean A or B. The "and / or" herein is only a description of the association relationship between associated objects, indicating that there can be three relationships. For example, A and / or B may mean: A exists alone, A and B exist simultaneously, and B exists alone. Herein, A and B may be singular or plural respectively.

[0074] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" or "connected on" another element, it can be directly connected to the other element or indirectly connected to the other element. When an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element.

[0075] It should be noted that the orientation or positional relationship indicated by terms such as "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as a limitation on the present invention.

[0076] It should be noted that the terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include one or more of such features.

[0077] It should be noted that the meaning of the term "plural" is two or more, unless otherwise specifically defined.

[0078] Please refer to Figures 1 to 17, the thrombus protector provided by the present invention will now be described. The thrombus protector includes: a seat body 1, a mesh pocket 21, a guide rod 3, a ring body 4, and a connecting wire 5; the mesh pocket 21 has a receiving cavity 211; the two ends of the guide rod 3 are respectively a first end 311 and a second end 321; the first end 311 is fixedly connected to the inner wall of the bottom of the receiving cavity 211; the second end 321 is connected to the seat body 1; the ring body 4 extends along the edge of the opening of the receiving cavity 211; the edge of the opening of the receiving cavity 211 is fixed on the ring body 4; the ring body 4 is sleeved outside the guide rod 3; the ring body 4 can be bent and deformed under an external force; after the external force is removed, the ring body 4 can return to a ring shape; a thrombus inlet channel 41 for allowing a thrombus 9 to enter the receiving cavity 211 is formed between the ring body 4 and the guide rod 3; the connecting wire 5 connects the ring body 4 and the second end 321; the ring body 4 is located between the first end 311 and the second end 321.

[0079] In this way, the guide rod 3 is arranged on the seat body 1. The two ends of the guide rod 3 are respectively a first end 311 and a second end 321, and the second end 321 is connected to the seat body 1. When the user moves the seat body 1, the guide rod 3 can be moved; the mesh pocket 21 has a receiving cavity 211. When the user releases the mesh pocket 21 into the blood vessel, the user can catch the thrombus 9 in the blood vessel through the receiving cavity 211; the edge of the opening of the receiving cavity 211 is fixed with a ring body 4, and the ring body 4 extends along the edge of the opening of the receiving cavity 211, so that the ring body 4 can support the edge of the opening of the receiving cavity 211; under an external force, the ring body 4 can be bent and deformed, so that the ring body 4 can be folded and stored under an external force, which is convenient for the folding and storage of the mesh pocket 21; when the ring body 4 is released into the blood vessel, the ring body 4 can return to a ring shape to open the opening of the receiving cavity 211, and the thrombus 9 can more easily enter the receiving cavity 211 from the opening of the receiving cavity 211; the first end 311 of the guide rod 3 is fixedly connected to the inner wall of the bottom of the receiving cavity 211, the ring body 4 is connected to the second end 321 through the connecting wire 5, and the ring body 4 is located between the first end 311 and the second end 321, so that the ring body 4 can maintain the stability of its relative position through the connecting wire 5 when in the blood vessel, and reduce the escape of the thrombus in the receiving cavity 211.

[0080] In one embodiment, regarding the "mesh bag 21": 【1】The term "mesh bag 21" refers to a bag-like structure made of a mesh material (such as fibers, wires, or plastics), which is usually used to load, capture, or wrap objects. The mesh bag 21 is designed to have a certain elasticity or stretchability, capable of accommodating objects and allowing them to pass through liquids, breathe, or circulate, while effectively keeping the objects inside the mesh bag 21 from being easily lost or scattered. The mesh bag 21 is widely used in multiple fields, including medical, sports, and daily life. 【2】The first example: The thrombus 9 capture mesh bag 21 in the medical field: In medical devices, the mesh bag 21 is often used in thrombus 9 capture catheters. Doctors introduce the device with the mesh bag 21 into the blood vessel through the catheter, and the function of the mesh bag 21 is to capture thrombus 9 or other obstructions in the blood vessel. This mesh bag 21 is designed to have sufficient elasticity to capture thrombus 9.

[0081] In one embodiment, the mesh bag 21 is foldable and / or bendable.

[0082] Further, please refer to Figures 1 to 17 , as a specific implementation manner of the thrombus protector provided by the present invention, the ring body 4 is: a shape memory alloy ring or an elastic ring. Thus, regarding the shape memory alloy ring: The shape memory alloy material (such as NiTi alloy) can restore the preset shape at the temperature in the human blood vessel, which enables the mesh bag 21 to adapt to the blood vessel environment and effectively unfold. Regarding the elastic ring: The flexibility and elasticity of the elastic ring enable the mesh bag 21 to unfold more smoothly in the narrow blood vessel, while causing less irritation to the blood vessel and reducing the damage to the blood vessel wall. The elastic ring can also effectively withstand the pressure changes in the blood vessel, maintain the stability of the mesh bag 21, and ensure that the mesh bag 21 can be firmly fixed when capturing thrombus 9.

[0083] In one embodiment, the elastic ring is made of silicone or rubber.

[0084] Further, please refer to Figures 1 to 17 , as a specific implementation manner of the thrombus protector provided by the present invention, the ring body 4 is: a NiTi alloy ring. Thus, NiTi alloy is a material with excellent shape memory effect. When the NiTi alloy ring is exposed in the blood vessel, it can automatically restore to the predetermined shape. In the blood vessel, with the change of body temperature, the NiTi alloy ring can self-regulate and quickly unfold, thereby ensuring that the mesh bag 21 can be quickly and accurately positioned in the blood vessel.

[0085] Further, please refer to Figures 1 to 17 , as a specific implementation manner of the thrombus protector provided by the present invention, the connecting wire 5 is: a shape memory alloy wire. Thus, the shape memory alloy material (such as NiTi alloy) can restore the preset shape at the temperature in the human blood vessel.

[0086] Further, please refer to Figures 1 to 17, as a specific embodiment of the thrombus protector provided by the present invention, the connecting wire 5 is: a nitinol wire. In this way, nitinol has extremely high strength and corrosion resistance, and can maintain its structural integrity during long-term use in blood vessels, and is not prone to deformation or corrosion.

[0087] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the ring body 4 and the mesh pocket 21 are connected by any one of welding, wire winding, knitting, and bonding. In this way, regarding welding: Connecting by welding can provide high mechanical strength, ensure a very firm connection between the ring body 4 and the mesh pocket 21, and prevent detachment due to external forces during thrombus capture. Regarding wire winding: Wire winding connection can be achieved by winding a thin wire material (such as stainless steel wire or polymer wire) between the mesh pocket 21 and the ring body 4 to form a firm connection. This method has a certain flexibility, can ensure the flexibility of the mesh pocket 21 during deployment, and adapt to the complex structure and pressure changes in blood vessels. Wire winding connection can also enhance the tensile strength between the mesh pocket 21 and the ring body 4, improving the reliability of the device. Regarding knitting: Knitting connection is usually used for softer materials, such as polymer mesh pocket 21. Through the knitting process, the ring body 4 and the mesh pocket 21 are connected in a weaving manner, which has good elasticity and adaptability, is suitable for fine-tuning the thrombus 9 during the capture process, and avoids damage to blood vessels caused by excessive tension. Knitting connection can provide higher flexibility and wear resistance, and is suitable for thrombus 9 capture that requires flexibility and high stretchability. Regarding bonding: Bonding is to connect the mesh pocket 21 and the ring body 4 by using a strong adhesive, which is suitable for precise designs, especially those involving the combination of different materials. The bonding connection method can avoid the abrupt seams brought by traditional mechanical connections, provide a smoother structural transition, reduce friction or damage to blood vessels. Bonding can also ensure a tight connection between the mesh pocket 21 and the ring body 4 without adding extra weight.

[0088] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the number of connecting wires 5 is multiple. In this way, multiple connecting wires 5 can improve the stability of the position of the ring body 4 itself.

[0089] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the number of connecting wires 5 is two. In this way, the connecting wires 5 can keep the ring body 4 stable at two positions.

[0090] Further, please refer to Figures 1 to 17, as a specific embodiment of the thrombus protector provided by the present invention, a support space is formed between multiple connecting wires 5; the support space communicates with the accommodation cavity 211; the external space communicates with the support space through the gaps between any adjacent connecting wires 5. In this way, the support space formed between multiple connecting wires 5; the communication between the support space and the accommodation cavity 211 ensures that the mesh bag 21 can flexibly adapt to thrombi 9 of different sizes and shapes. The external space communicates with the support space through the gaps between any adjacent connecting wires 5, so that the blood flow is not subject to excessive resistance. Blood can flow through these gaps, avoiding the situation where the mesh bag 21 obstructs blood flow, and at the same time reducing the pressure on the inner wall of the blood vessel, providing higher biocompatibility and safety.

[0091] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, along the extension direction of the guiding rod 3 from the first end 311 to the second end 321, the cross-section of the support space gradually narrows. In this way, the design of the gradually narrowing cross-section of the support space enables the mesh bag 21 to gradually contract or expand in the guiding rod 3 according to the size and position of the blood vessel. The gradually narrowing cross-section of the support space can also optimize the blood flow path and reduce the obstruction of the mesh bag 21 to blood flow.

[0092] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the mesh bag 21 is: a metal braided mesh; or the mesh bag 21 is: a perforated polymer plastic mesh. In this way, the metal braided mesh has excellent mechanical strength and elasticity, enabling it to withstand higher tensile and compressive forces and adapt to the expansion and contraction in a complex blood vessel environment. The polymer plastic mesh can customize the shape and pore size of the mesh bag 21 through the formable characteristics of the plastic material to adapt to different types of thrombi 9. The perforated design can not only provide better capture effect, but also ensure the fluidity of blood while reducing the mass of the mesh bag 21.

[0093] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the mesh bag 21 is: a nitinol wire braided mesh. In this way, the mesh bag 21 is woven from nitinol wires and can automatically expand in the blood vessel and maintain the stability and shape of the mesh bag 21.

[0094] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, it further includes: a first ring 61 sleeved and fixed on the first end 311; the first ring 61 is made of any one of platinum, platinum-iridium alloy, and gold. In this way, the first ring 61 can act as a radiopaque ring.

[0095] Further, please refer to Figures 1 to 17, as a specific embodiment of the thrombus protector provided by the present invention, the connection part of the mesh bag 21 with the first end 311 is clamped between the first ring 61 and the first end 311. In this way, the first end 311 of the mesh bag 21 is more stable under the clamping of the first ring 61.

[0096] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, it further includes: a second ring 62 sleeved and fixed on the second end 321; the second ring 62 is made of any one of platinum, platinum-iridium alloy, and gold. In this way, the second ring 62 can act as a visualization ring.

[0097] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, it further includes: a guide wire 81; one end of the guide wire 81 is connected to the first end 311; the other end of the guide wire 81 is located outside the mesh bag 21. In this way, the guide wire 81 can play a guiding role.

[0098] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, it further includes: a containment cylinder 22, a traction wire 83, and a tractor 82 provided on the seat body 1; the two ends of the containment cylinder 22 are respectively an first opening 221 and a second opening 222; the edge of the first opening 221 is fixed on the ring body 4, and the ring body 4 extends along the edge of the first opening 221; the tractor 82 is connected to the edge of the second opening 222 through the traction wire 83, and the traction wire 83 can pull the edge of the second opening 222 in a direction away from the first end 311 to sleeved the containment cylinder 22 outside the connecting wire 5. In this way, after the traction wire 83 pulls the edge of the second opening 222 in a direction away from the first end 311, the containment cylinder 22 can be sleeved outside the connecting wire 5, and the containment cylinder 22 can surround the outside of the opening of the accommodation cavity 211, reducing the risk of the thrombus 9 in the accommodation cavity 211 falling off and escaping again or being carried to other areas. During the intravascular treatment process, through the traction effect with the ring body 4, the position of the containment cylinder 22 can be adjusted and the containment cylinder 22 can be firmly covered on the thrombus 9 to ensure the treatment effect.

[0099] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the containment cylinder 22 can be folded and sleeved on the outer wall of the mesh bag 21. In this way, the containment cylinder 22 can be stored outside the mesh bag 21 to save space.

[0100] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the containment cylinder 22 is an integral part made of elastic material. In this way, the containment cylinder 22 can change its own shape to adapt to the intravascular environment.

[0101] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the containment cylinder 22 is made by blow molding from any one of the following materials: nylon, pebax (pebax: block polyether amide resin), and polyester film. In this way, nylon, as a wear-resistant and high-strength material, can withstand high pressure and traction forces within blood vessels, ensuring that the containment cylinder 22 is not easily ruptured or damaged during treatment. Pebax, as a material with excellent elasticity and durability, can maintain long-term stability within blood vessels. Polyester film has strong tensile strength and high heat resistance, ensuring that the containment cylinder 22 maintains its shape in a complex blood vessel environment.

[0102] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, a plurality of through holes are provided on the containment cylinder 22. In this way, blood flow can pass through the through holes.

[0103] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the tractor 82 includes: a toggle switch; the toggle switch is slidably arranged on the base body 1; one end of the traction wire 83 is connected to the toggle switch, and the other end of the traction wire 83 is connected to the edge of the second opening 222 of the containment cylinder 22. In this way, the toggle switch can pull the containment cylinder 22 to move through the traction wire 83.

[0104] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the traction wire 83 can be made from any one of the following materials: nitinol, stainless steel, and nylon ribbon wire. In this way, nitinol alloy (shape memory alloy) has excellent shape memory effect and elasticity. Stainless steel, as a high-strength and corrosion-resistant material, has excellent tensile strength and toughness. Nylon ribbon wire has good flexibility and biocompatibility.

[0105] Further, please refer to Figures 1 to 17 , as a specific embodiment of the thrombus protector provided by the present invention, the guide rod 3 has a wire inlet channel inside, and the traction wire 83 passes through the wire inlet channel and is connected to the toggle switch. In this way, the traction wire 83 can be stored in the wire inlet channel.

[0106] Further, please refer to Figures 1 to 17As a specific embodiment of the thrombus protector provided by the present invention, the guide rod 3 includes: a hypotube 31 (hypotube 31: Hibiscus Tube) and a sleeve 32; the hypotube 31 and the sleeve 32 are respectively connected to the seat body 1; one end of the hypotube 31 is a first end 311, and the sleeve 32 is sleeved on the other end of the hypotube 31; the end of the sleeve 32 close to the first end 311 is a second end 321; a wire feeding channel is formed between the sleeve 32 and the hypotube 31. In this way, the sleeve 32 can protect the internal hypotube 31, and the hypotube 31 is prone to deformation.

[0107] In one embodiment, the hypotube 31 is made of a polymer material (such as polyurethane (PU), polyamide (nylon), polytetrafluoroethylene (PTFE), PEBAX, etc.). These materials have good flexibility, corrosion resistance and biocompatibility, and can ensure long-term use in blood vessels without causing tissue irritation or allergic reactions. In one embodiment, the hypotube 31 is made of materials such as stainless steel or nickel-titanium alloy to enhance its strength and stability. These metal materials can provide higher tensile strength to help the catheter maintain its shape and withstand external pressure during operation.

[0108] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the outer surface of the hypotube 31 has a spiral groove 312 formed by laser processing. In this way, the spiral groove 312 can improve the bending ability of the hypotube 31.

[0109] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, it also includes: an ultrasonic generator arranged on the seat body 1, and the ultrasonic generator is connected to the guide rod 3. In this way, the ultrasonic wave is transmitted to the guide rod 3, and the ultrasonic wave guided is transmitted to the net bag 21, thereby reducing the adhesion of the thrombus 9 to the net bag 21.

[0110] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, it also includes: a medicine bag containing a thrombolytic drug disposed in the accommodating cavity 211. In this way, the thrombus 9 in the accommodating cavity 211 can be dissolved after the thrombus 9 in the accommodating cavity 211 is released.

[0111] For further information, see Figures 1 to 17 As a specific embodiment of the thrombus protector provided by the present invention, the medicine bag has an opening; the opening is covered with a protective cover; the protective cover is rotatably arranged on the medicine bag; the protective cover is connected to a pulling line for pulling and opening the protective cover. In this way, after the user opens the protective cover by pulling the line, the medicine can be discharged into the accommodating cavity 211 through the opening.

[0112] For further information, seeFigures 1 to 17 , as a specific implementation of the thrombus protector provided by the present invention, a mesh body is laid on the inner wall of the accommodation cavity 211; the mesh body and the inner wall of the accommodation cavity 211 are fixedly connected through a plurality of fasteners. In this way, the mesh body can provide sequential filtration for the blood in the accommodation cavity 211, and the mesh pocket 21 can provide a second filtration. The mesh body and the mesh pocket 21 can together enhance the ability to intercept the thrombus 9.

[0113] Further, please refer to Figures 1 to 17 , as a specific implementation of the thrombus protector provided by the present invention, the mesh holes on the mesh body are smaller than the mesh holes on the mesh pocket 21. In this way, the ability of the mesh body inside the mesh pocket 21 to intercept the thrombus 9 is greater than that of the mesh pocket 21 to intercept the thrombus 9, so that finer thrombi 9 can be trapped by the mesh body inside the mesh pocket 21, reducing the possibility of the thrombus 9 leaking from the mesh pocket 21.

[0114] Further, please refer to Figures 1 to 17 , as a specific implementation of the thrombus protector provided by the present invention, there is a spaced arrangement between the mesh body and the inner wall of the accommodation cavity 211. In this way, when the blood is filtered successively through the mesh body and the mesh pocket 21, the thrombus 9 adhered to the mesh body is not easily adhered to the inner wall of the accommodation cavity 211, reducing the simultaneous blockage of the mesh body and the mesh pocket 21 by the thrombus 9.

[0115] Further, please refer to Figures 1 to 17 , as a specific implementation of the thrombus protector provided by the present invention, the mesh holes on the mesh body and the mesh holes on the mesh pocket 21 are arranged in a staggered manner. In this way, part of the thrombus 9 is easily intercepted by the mesh pocket 21 when passing through the mesh holes on the mesh body.

[0116] Further, please refer to Figures 1 to 17 , as a specific implementation of the thrombus protector provided by the present invention, a thrombolytic drug coating for reducing the formation of thrombus 9 is covered on the inner wall of the mesh pocket 21. In this way, when the blood remains in the mesh pocket 21, the thrombolytic drug can reduce the generation of thrombus 9 in the mesh pocket 21.

[0117] Further, please refer to Figures 1 to 17 , as a specific implementation of the thrombus protector provided by the present invention, any two adjacent meshes on the mesh pocket 21 are rotatably connected to each other. In this way, the adjacent meshes on the mesh pocket 21 can rotate relative to each other to change the relative position, and the relative rotation of the adjacent meshes can change the shape of the mesh pocket 21.

[0118] Further, please refer to Figures 1 to 17 , as a specific implementation of the thrombus protector provided by the present invention, it further includes: a universal coupling structure; any two adjacent meshes on the mesh pocket 21 are respectively rotatably connected through the universal coupling structure. In this way, the adjacent meshes can rotate relative to each other very conveniently through the universal coupling structure.

[0119] In one embodiment, the universal coupling structure is: a universal coupling.

[0120] Further, please refer to Figure 18 , as a specific embodiment of the thrombus protector provided by the present invention, when the guide rod 3 extends along the x-axis and the mesh pocket 21 is opened, in the axial section passing through the axis of the guide rod 3 and vertically arranged, the trajectory of the outer wall of the mesh pocket 21 on one side of the x-axis is parallel to y = 0.0001*x^3 + 0.01*x^2 - 0.5*x (where -85 ≤ x ≤ 19), and the trajectories of the outer walls of the mesh pockets 21 on both sides of the guide rod 3 are axisymmetric (in one embodiment, the trajectories of the outer walls of the mesh pockets 21 on both sides of the guide rod 3 are symmetrically arranged on both sides of the x-axis. In one embodiment, the axis of the guide rod 3 is the x-axis. In one embodiment, the x-axis is the axis of symmetry of the guide rod 3). Thus, when -85 ≤ x ≤ 19, the trajectory of y is located between the peak value H1 on the left side of the Y-axis and the trough value H2 on the right side of the Y-axis. 【1】Smoothing curve characteristic: The cubic term (x^3) and the quadratic term (x^2) make the side wall show a smooth and continuous change, without sharp inflection points or irregular mutations. This is very important for the deployment of the mesh pocket 21, because the smooth curve can ensure that the mesh pocket 21 is evenly deployed in the blood vessel, avoiding excessive pressure on the blood vessel wall caused by the mutation point and reducing the damage to the blood vessel. 【2】Bending characteristic: The combination of the "negative first-order term (-0.5x)" and other terms affects the inclination degree of the curve. The curve gradually bends downward when the x value is between H1 and H2, which indicates that the side wall of the mesh pocket 21 gradually contracts within a certain range. This design may be used to adapt to the curvature changes of different blood vessels. This change characteristic of the side wall of the mesh pocket 21 ensures its adaptability in the complex blood vessel structure and can adjust with the change of the blood vessel shape. 【3】Adapting to complex blood vessels: The change of the curve allows the side wall of the mesh pocket 21 to be flexibly adjusted according to the size, shape of the blood vessel and the blood flow velocity. When the curve change in the blood vessel is large, the side wall of the mesh pocket 21 can effectively adapt to the complex environment of the blood vessel through this non-linear change, ensuring that the thrombus 9 is firmly wrapped.

[0121] In one embodiment, the containment cylinder 22 is connected to the mesh pocket 21 by any one of welding, wire winding knitting bonding.

[0122] In one embodiment, the first ring 61 is a circular ring.

[0123] In one embodiment, the second ring 62 is a circular ring.

[0124] In one embodiment, the mesh pocket 21 made of metal braiding or polymer molding has a self-expansion function and can automatically expand and fit the inner wall of the blood vessel after being delivered out of the mouth of the delivery catheter.

[0125] In one embodiment, the connecting wire 5 is a memory alloy support wire. The memory alloy support wire is used to support the containment tube 22, so that it can maintain the gourd shape when the containment tube 22 is released. Its material is the same as the memory alloy support ring (i.e., the ring body 4) at the mouth of the net bag 21. In one embodiment, the connecting wire 5 can be connected to the sleeve 32 by riveting / welding / bonding / inlaying. In one embodiment, the connecting wire 5 can be connected to the ring body 4 by riveting / welding / bonding / inlaying.

[0126] In one embodiment, the connecting wire 5 is arched toward the outside.

[0127] In one embodiment, the connecting wire 5 is partially and smoothly connected to the net bag 21 .

[0128] In one embodiment, the sleeve 32 is a bendable metal tube.

[0129] In one embodiment, the sea wave tube 31 is inside the entire protector net bag 21 and is in a spiral hollow shape. This structure can be achieved by laser cutting to provide compliance for the protector net bag 21. The distal end of the inner sea wave tube 31 is connected to the first ring 61 and the head end of the net bag 21 by riveting / welding / bonding / inlaying.

[0130] In one embodiment, the guide wire 81 is made of winding wire or soft elastomeric material, and plays a guiding role. The guide wire 81 is connected to the inner layer hypotube 31 by riveting / welding / bonding / inserting. In one embodiment, the guide wire 81 is connected to the first ring 61 by riveting / welding / bonding / inserting.

[0131] In one embodiment, the seat body 1 is made of polycarbonate or polyethylene material.

[0132] In one embodiment, the tractor 82 is a button, which is made of polycarbonate, polyethylene or metal.

[0133] In one embodiment, the traction wire 83 is connected to the first ring 61 by bonding / welding, inlaying, etc. In one embodiment, the traction wire 83 is connected to the tractor 82 by bonding / welding, inlaying, etc.

[0134] In one embodiment, the sleeve 32 is a hollow structure made of metal materials such as stainless steel or nickel titanium tube.

[0135] In one embodiment, the distal end of the net bag 21 is connected to the guide wire 81 , and the metal braided or polymer-molded net bag 21 is connected to the hypotube 31 .

[0136] See also Figures 1 to 17, the present invention also provides a thrombus protection catheter, comprising: a tube body and a thrombus protector; the tube body has a lumen, and the mesh pocket 21 is received in the tube body. In this way, the mesh pocket 21 can be first received in the lumen, and after the tube body is removed, the mesh pocket 21 can be exposed in the blood vessel; due to the adoption of the above-mentioned thrombus protector, the guide rod 3 is arranged on the seat body 1, and the two ends of the guide rod 3 are respectively a first end 311 and a second end 321, and the second end 321 is connected to the seat body 1, and the user can move the guide rod 3 by moving the seat body 1; the mesh pocket 21 has a receiving cavity 211, when the user releases the mesh pocket 21 into the blood vessel, the user can catch the thrombus 9 in the blood vessel through the receiving cavity 211; a ring body 4 is fixed to the edge of the opening of the receiving cavity 211, and the ring body 4 extends along the edge of the opening of the receiving cavity 211, so that the ring body 4 can support the edge of the opening of the receiving cavity 211; under an external force, the ring body 4 can be bent and deformed, so that the ring body 4 can be folded and received under the external force, which is convenient for the folding and receiving of the mesh pocket 21; when the ring body 4 is released into the blood vessel, the ring body 4 can be restored to a ring shape to open the opening of the receiving cavity 211, and the thrombus 9 can more easily enter the receiving cavity 211 through the opening of the receiving cavity 211; the first end 311 of the guide rod 3 is fixedly connected to the inner wall of the bottom of the receiving cavity 211, and the ring body 4 is connected to the second end 321 through a connecting wire 5, and the ring body 4 is located between the first end 311 and the second end 321, so that the ring body 4 can maintain the stability of its relative position through the connecting wire 5 when in the blood vessel, and reduce the escape of thrombus in the receiving cavity 211.

[0137] The above are only the preferred embodiments of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the technical principle of the present invention, several improvements and substitutions can be made, and these improvements and substitutions should also be regarded as the protection scope of the present invention.

Claims

1. A thrombus protector, characterized in that: include: seat body; Net bag; The net bag has a receiving cavity; A guide rod; the two ends of the guide rod are respectively a first end and a second end; the first end is fixedly connected to the inner wall of the bottom of the accommodating cavity; the second end is connected to the seat body; A ring body; the ring body extends along the edge of the opening of the accommodating cavity; the edge of the opening of the accommodating cavity is fixed on the ring body; the ring body is sleeved on the outside of the guide rod; the ring body can be bent and deformed under the action of external force; after the external force is removed, the ring body can return to a ring shape; a thrombus entry channel for allowing thrombus to enter the accommodating cavity is formed between the ring body and the guide rod; Connecting wire; The connecting wire connects the ring body and the second end; The ring body is located between the first end and the second end; It also includes: a containment tube, a traction wire, and a traction device arranged on the seat body; the openings at both ends of the containment tube are respectively a first opening and a second opening; the edge of the first opening is fixed on the ring body, and the ring body extends along the edge of the first opening; the traction device is connected to the edge of the second opening through the traction wire, and the containment tube can be folded and sleeved on the outer wall of the net bag; the traction wire can pull the edge of the second opening in a direction away from the first end to sleeve the containment tube on the outside of the connecting wire, and the containment tube can block the outside of the opening of the accommodating cavity.

2. The thrombus protector according to claim 1, characterized in that: The number of the connecting wires is multiple.

3. The thrombus protector according to claim 2, characterized in that: The number of the connecting wires is two.

4. The thrombus protector according to claim 2, characterized in that: A supporting space is formed between the plurality of connecting wires; the supporting space is communicated with the accommodating cavity; and the external space is communicated with the supporting space through the gaps between any adjacent connecting wires.

5. The thrombus protector according to claim 4, characterized in that: Along the extension direction of the guide rod from the first end to the second end, the cross section of the support space gradually narrows.

6. The thrombus protector according to claim 1, characterized in that: Also includes: Guidewire; One end of the guide wire is connected to the first end; the other end of the guide wire is located outside the net bag.

7. The thrombus protector according to claim 1, characterized in that: The containment cylinder is an integral piece made of elastic material.

8. The thrombus protector according to claim 1, characterized in that: The traction device comprises: a toggle switch; the toggle switch is slidably arranged on the seat body; one end of the traction wire is connected to the toggle switch, and the other end of the traction wire is connected to the second opening edge of the containment cylinder.

9. The thrombus protector according to claim 8, characterized in that: The guide rod is provided with a wire feeding channel, and the traction wire passes through the wire feeding channel and is connected to the toggle switch.

10. The thrombus protector according to claim 9, characterized in that: The guide rod includes: a hypotube and a sleeve; the hypotube and the sleeve are respectively connected to the seat body; one end of the hypotube is the first end, and the sleeve is sleeved on the other end of the hypotube; the end of the sleeve close to the first end is the second end; the wire feeding channel is formed between the sleeve and the hypotube.

11. The thrombus protector according to any one of claims 1 to 6, characterized in that: A mesh is laid on the inner wall of the accommodating cavity; the mesh is fixedly connected to the inner wall of the accommodating cavity by a plurality of fasteners.

12. The thrombus protector according to any one of claims 1 to 6, characterized in that: Any adjacent grids on the net bag are rotatably connected to each other.

13. The thrombus protector according to any one of claims 1 to 6, characterized in that: When the guide rod extends along the x-axis and the net bag is opened, in an axial section passing through the axis of the guide rod and vertically arranged, the trajectory of the outer wall of the net bag on one side of the x-axis is parallel to y=0.0001*x^3+0.01*x^2-0.5*x; wherein, -85≤x≤19, and the trajectories of the outer walls of the net bag on both sides of the guide rod are axially symmetrical.

14. An embolic protection catheter, characterized in that: include: A tube body and a thrombus protector as claimed in any one of claims 1 to 13; the tube body has a lumen, and the net bag is received in the lumen.

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