Yin-nourishing and blood-nourishing headache granules for treating dull head pain

Through the qiyin and blood headache granules, the compatibility effect of Chinese medicinal materials such as ginseng, Atractylodes, and Angelica sinensis was used to solve the problem of insufficient efficacy of existing treatment plans, and achieved significant therapeutic effect and high safety effect on head pain.

CN119792406APending Publication Date: 2025-04-11CHONGQING YUJUNFANG INTELLIGENT MEDICAL TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202510061636.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-15
Publication Date
2025-04-11

AI Technical Summary

Technical Problem

The existing treatment plans for head pain are insufficient, slow to function or have side effects, and there are lack of Chinese patent medicine formulas specifically designed to nourish yin and blood, which cannot meet the diverse needs of patients.

Method used

It provides a kind of yin-nourishing and blood-nourishing headache granules, the main ingredients include ginseng, Atractylodes macrocephala, Angelica sinensis, roasted licorice, cooked Rehmannia, Poria, peony and Chuanxiong. Through scientifically matched Chinese herbal medicines, it replenishes qi and blood, nourishes yin and regulates yin, and comprehensively treats the causes of dull headache pain.

Benefits of technology

This granule has the characteristics of significant efficacy, easy to take and high safety. It can effectively relieve symptoms such as headache, swelling, fatigue and fatigue, improve headache and dizziness caused by insufficient qi and blood, and improve immunity and sleep quality.

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Abstract

The invention discloses a yin-nourishing blood-nourishing headache granule for treating dull head pain, which comprises the following main traditional Chinese medicine components in parts by weight: 5 to 10 parts of ginseng, 5 to 15 parts of bighead atractylodes rhizome, 10 to 20 parts of Chinese angelica, 3 to 8 parts of honey-fried licorice root, 10 to 25 parts of prepared rehmannia root, 5 to 15 parts of poria cocos, 10 to 20 parts of Chinese herbaceous peony and 10 to 20 parts of szechuan lovage rhizome, and also comprises the following raw materials in parts by weight: 5 to 10 parts of ginseng, 5 to 15 parts of bighead atractylodes rhizome, 10 to 20 parts of Chinese angelica, 3 to 8 parts of honey-fried licorice root, 10 to 25 parts of prepared rehmannia root, 5 to 15 parts of poria cocos, 10 to 20 parts of Chinese herbaceous peony and 10 to 20 parts of szechuan lovage rhizome. The Chinese herbal medicine components preferably comprise the following components: 8 parts of ginseng, 10 parts of bighead atractylodes rhizome, 15 parts of angelica sinensis, 5 parts of honey-fried licorice root, 18 parts of prepared rehmannia root, 10 parts of poria cocos, 15 parts of Chinese herbaceous peony and 15 parts of ligusticum wallichii; the dosage of the granules is 5-10 g for adults each time, the specific dosage can be adjusted according to the symptoms, and the granules are taken 2-3 times every day; according to the taking mode, the granules are taken after being mixed with warm boiled water and fully stirred, the granules are drunk after being completely dissolved, generally, the granules are continuously taken for 7-10 days, and if symptoms are relieved, the dosage can be properly reduced.
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Description

Technical Field

[0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to yin-nourishing and blood-nourishing headache granules for treating dull headaches. Background Art

[0002] Headache is a common clinical symptom, which is mainly manifested as persistent dull pain, bloating or dull pain, usually accompanied by fatigue, dizziness, memory loss and other symptoms. According to Chinese medicine, headache is mostly caused by insufficient Qi and blood, imbalance of Yin and Yang, especially in patients with long-term fatigue, weak constitution or chronic diseases. Traditional methods of treating headache include adjusting lifestyle, psychological counseling and drug treatment. However, while existing treatment options can relieve symptoms, they often have problems such as insufficient efficacy, slow effect or large side effects. An efficient and safe treatment method is urgently needed.

[0003] Traditional Chinese medicine has a long history and rich practical experience in treating headaches. The method of nourishing yin and blood is one of the classic theories of TCM for treating headaches. It mainly replenishes the yin fluid and blood in the body to achieve the effect of balancing yin and yang and relieving pain. However, there are few types of Chinese patent medicines for headaches on the market, and there is a lack of formulas specifically for nourishing yin and blood, which cannot meet the diverse needs of patients.

[0004] Based on the above problems, the present invention provides a headache granule formula with nourishing yin and blood as the core, and selects classic Chinese medicinal materials such as ginseng, atractylodes, angelica, roasted licorice, cooked rehmannia, poria, peony and ligusticum chuanxiong. These medicinal materials are scientifically matched to effectively replenish qi and blood, nourish yin and regulate, and specifically treat the causes of headaches comprehensively, with the characteristics of significant efficacy, easy administration and high safety. Summary of the invention

[0005] The purpose of the present invention is to solve the shortcomings of the prior art and provide a Yin-nourishing and blood-nourishing headache granule for treating dull headache.

[0006] In order to achieve the above object, the present invention provides the following technical solutions: Disclosed is a Yin-nourishing and blood-nourishing headache granule for treating hidden headache. The main Chinese medicinal ingredients of the granule include ginseng, atractylodes macrocephala, angelica sinensis, roasted liquorice, prepared rehmannia, Poria cocos, peony and Chuanxiong. The proportion of each ingredient in parts by weight is: 5-10 parts of ginseng, 5-15 parts of atractylodes macrocephala, 10-20 parts of angelica sinensis, 3-8 parts of roasted liquorice, 10-25 parts of prepared rehmannia, 5-15 parts of Poria cocos, 10-20 parts of peony and 10-20 parts of Chuanxiong. The Chinese herbal medicine ingredients may preferably include the following components: 8 parts of ginseng, 10 parts of atractylodes macrocephala, 15 parts of angelica sinensis, 5 parts of roasted liquorice, 18 parts of prepared rehmannia, 10 parts of Poria cocos, 15 parts of peony and 15 parts of Chuanxiong.

[0007] Furthermore, the ginseng has the effects of invigorating qi and strengthening the spleen, replenishing the body's positive energy, improving immunity, helping to relieve fatigue and weakness caused by qi deficiency, calming the mind and soothing the nerves: regulating the central nervous system, helping to relieve headaches and dizziness, and improving sleep quality; the white atractylodes can invigorate the spleen and replenish qi, help the spleen and stomach digest and absorb, improve the symptoms of physical weakness caused by spleen deficiency, and promote diuresis and eliminate dampness: reduce moisture retention in the body, thereby relieving dizziness and headache; the angelica can replenish blood and promote blood circulation, improve dizziness symptoms caused by blood deficiency, regulate menstruation and relieve pain, and relieve headaches caused by qi stagnation and blood stasis, especially migraine.

[0008] Furthermore, the roasted licorice harmonizes the various medicines, enhances the overall coordination of the formula, makes the medicinal properties of each medicinal material more harmonious, nourishes the spleen and replenishes qi, helps to strengthen the physical fitness, and improves headaches and fatigue caused by spleen deficiency; the cooked rehmannia nourishes yin and blood, replenishes the liver and kidney yin fluid, helps to improve headaches and dizziness caused by kidney deficiency, replenishes essence and marrow, helps to improve brain function, and enhances memory and concentration; the poria promotes diuresis and moisture absorption, promotes water metabolism in the body, helps to reduce the feeling of head swelling caused by moisture, strengthens the spleen and calms the mind, relieves anxiety, and improves the symptoms of lack of energy and dizziness caused by spleen deficiency.

[0009] Furthermore, the peony calms the liver and relieves pain, helps soothe the liver and regulate qi, relieves headaches, and is particularly suitable for headaches caused by liver qi stagnation, softens the liver and nourishes blood, improves blood deficiency symptoms, and helps relieve dizziness caused by poor blood circulation; the chuanxiong promotes blood circulation and qi, dredges the meridians, improves headaches and migraines caused by qi and blood stasis, dispels wind and relieves pain, and is used to relieve headaches caused by wind-cold and improves symptoms of heaviness and swelling in the head.

[0010] Furthermore, the particles are prepared by the following process steps: a. Weigh the following herbs by weight: 5-10 parts of ginseng, 5-15 parts of Atractylodes macrocephala, 10-20 parts of Angelica sinensis, 3-8 parts of licorice, 10-25 parts of Rehmannia glutinosa, 5-15 parts of Poria cocos, 10-20 parts of peony, 10-20 parts of Chuanxiong; b. Wash each raw medicinal material with clean water, remove impurities, and dry them for later use; c. Take each ingredient and grind them into fine powder according to their weight ratio; d. Mix all the fine powders evenly and add appropriate amount of water to form a moist mixture; e. Add appropriate amount of auxiliary materials, such as dextrin or starch, as needed to improve the formability of the particles and the stability of the drug, add appropriate amount of purified water, mix into a soft material mixture, stir until uniform, and control the humidity at 10%-15%; f. forming the soft material mixture into granules by a wet granulator; g. Place the prepared granules in a dryer and dry them at 50-60°C until the moisture content of the granules is less than 5%.

[0011] Furthermore, the granules are used to treat anemia caused by deficiency of both qi and blood, chronic blood loss, irregular menstruation, functional uterine bleeding, habitual abortion, postpartum evil leakage, chronic nephritis, chronic hepatitis, chronic bronchitis, chronic diarrhea, allergic purpura, arrhythmia, coronary heart disease, chronic heart failure, leukopenia, thrombocytopenic purpura, chronic osteomyelitis and other diseases, accompanied by dull headache, which occurs suddenly, stops suddenly, and worsens with overwork, and may be accompanied by palpitations and insomnia, pale complexion, fatigue, and the tongue coating is pale and thin with white fur.

[0012] Furthermore, the dosage of the granules is 5 to 10 grams of granules per time for adults, and the specific dosage can be adjusted according to the severity of the symptoms, and taken 2-3 times a day; for children or the elderly, it is recommended to reduce the dosage appropriately according to age and physical condition, and it is generally recommended to take 3-5 grams each time, twice a day; it is recommended to take it half an hour after a meal to reduce irritation to the stomach and ensure the absorption of the drug effect; for the method of taking, the granules are taken with warm boiled water, stirred thoroughly, and drunk after ensuring that the granules are completely dissolved. It is generally taken continuously for 7-10 days, and the dosage can be appropriately reduced if the symptoms are relieved.

[0013] In the above technical scheme, the Yin-nourishing and blood-nourishing headache granules for treating headache have the following beneficial effects: (1) Calming the Liver and Suppressing Yang: The granule formula contains ingredients such as Chuanxiong, Paeonia lactiflora and Rehmannia glutinosa, which help regulate the hyperactivity of liver yang and relieve headaches and head swelling caused by excessive liver fire. By calming liver yang and suppressing liver fire, it improves the symptoms of head swelling and dizziness caused by hyperactivity of liver yang.

[0014] (2) Soothing the liver and regulating qi: Ingredients such as ginseng, white atractylodes and chuanxiong work together to help dredge liver qi and promote the circulation of qi and blood, thereby alleviating symptoms such as headaches and head swelling. This has a significant effect on migraines and dizziness caused by liver qi stagnation.

[0015] (3) Replenishing Qi and Blood: The ginseng, angelica and cooked rehmannia in this formula can nourish Qi and blood and strengthen the body. They are particularly suitable for headaches and dizziness caused by insufficient Qi and blood. The effect of replenishing Qi and blood can also effectively improve the accompanying symptoms such as fatigue and weakness caused by physical weakness.

[0016] (4) Promoting blood circulation and removing blood stasis: Ingredients such as Chuanxiong and Angelica have the effect of promoting blood circulation and removing blood stasis, which helps to improve blood circulation, relieve headache symptoms caused by blood stasis, prevent blood vessel blockage, and improve poor blood supply to the head.

[0017] (5) Strengthening the spleen and calming the mind: Ingredients such as Atractylodes macrocephala and Poria cocos help strengthen the spleen and promote diuresis, enhance the digestive and absorptive functions of the spleen and stomach, and effectively relieve dizziness, headache, and other discomforts caused by weak spleen and stomach. In addition, roasted licorice and Poria cocos can calm the mind and calm the mind, help relieve anxiety and tension, and improve headaches caused by mental stress.

[0018] (6) Eliminate dampness and reduce swelling: Poria cocos has the effect of promoting diuresis and removing dampness, which helps to eliminate excess water in the body and reduce edema and heaviness in the head. It is especially suitable for headaches and head swelling caused by excessive dampness.

[0019] (7) Improve drug absorption and utilization: The granular dosage form is easy to take, which improves the absorption and utilization rate of the drug, ensures that the active ingredients are quickly released and act on the lesions, and has the effect of quickly relieving symptoms. DETAILED DESCRIPTION

[0020] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below.

[0021] The embodiment of the present invention provides a Yin-nourishing and blood-nourishing headache granule for treating hidden headache. The main Chinese medicinal ingredients of the granule include ginseng, atractylodes macrocephala, angelica, roasted licorice, cooked rehmannia, Poria, peony and Chuanxiong. The ratio of each ingredient in parts by weight is: 5-10 parts of ginseng, 5-15 parts of atractylodes macrocephala, 10-20 parts of angelica, 3-8 parts of roasted licorice, 10-25 parts of cooked rehmannia, 5-15 parts of Poria, 10-20 parts of peony, and 10-20 parts of Chuanxiong; the Chinese herbal medicine ingredients may preferentially include the following components: 8 parts of ginseng, 10 parts of atractylodes macrocephala, 15 parts of angelica, 5 parts of roasted licorice, 18 parts of cooked rehmannia, 10 parts of Poria, 15 parts of peony, and 15 parts of Chuanxiong.

[0022] In one embodiment provided by the present invention, ginseng has the effects of invigorating qi and strengthening the spleen, replenishing the body's positive qi, improving immunity, helping to relieve fatigue and weakness caused by qi deficiency, calming the mind and soothing the nerves: regulating the central nervous system, helping to relieve headaches and dizziness, and improving sleep quality; white atractylodes can invigorate the spleen and replenish qi, help the spleen and stomach digest and absorb, improve the symptoms of physical weakness caused by spleen deficiency, and promote diuresis and moisture removal: reduce moisture retention in the body, thereby relieving dizziness and headache; angelica can replenish blood and promote blood circulation, improve dizziness symptoms caused by blood deficiency, regulate menstruation and relieve pain, and relieve headaches caused by qi stagnation and blood stasis, especially migraine.

[0023] Roasted licorice harmonizes the various medicines, enhancing the overall coordination of the formula, making the medicinal properties of each ingredient more harmonious, tonifying the spleen and replenishing qi, helping to strengthen the physical fitness, and improving headaches and fatigue caused by spleen deficiency; cooked rehmannia nourishes yin and blood, replenishes the yin fluid of the liver and kidneys, helps to improve headaches and dizziness caused by kidney deficiency, replenishes essence and benefits the marrow, helps to improve brain function, and enhances memory and concentration; poria promotes diuresis and eliminates dampness, promotes water metabolism in the body, helps to relieve the feeling of head swelling caused by dampness, tonifies the spleen and calms the mind, relieves anxiety, and improves symptoms of lack of energy and dizziness due to spleen deficiency.

[0024] Peony calms the liver and relieves pain, helps soothe the liver and regulate qi, and relieves headaches. It is especially suitable for headaches caused by liver qi stagnation, softens the liver and nourishes blood, improves symptoms of blood deficiency, and helps relieve dizziness caused by poor blood circulation; Chuanxiong promotes blood circulation and qi, dredges the meridians, improves headaches and migraines caused by qi and blood stasis, dispels wind and relieves pain, and is used to relieve headaches caused by wind-cold, and improves symptoms of heaviness and swelling in the head.

[0025] In another embodiment provided by the present invention, the particles are prepared by the following process steps: a. Weigh the following herbs by weight: 5-10 parts of ginseng, 5-15 parts of Atractylodes macrocephala, 10-20 parts of Angelica sinensis, 3-8 parts of licorice, 10-25 parts of Rehmannia glutinosa, 5-15 parts of Poria cocos, 10-20 parts of peony, 10-20 parts of Chuanxiong; b. Wash each raw medicinal material with clean water, remove impurities, and dry them for later use; c. Take each ingredient and grind them into fine powder according to their weight ratio; d. Mix all the fine powders evenly and add appropriate amount of water to form a moist mixture; e. Add appropriate amount of auxiliary materials, such as dextrin or starch, as needed to improve the formability of the particles and the stability of the drug, add appropriate amount of purified water, mix into a soft material mixture, stir until uniform, and control the humidity at 10%-15%; f. forming the soft material mixture into granules by a wet granulator; g. Place the prepared granules in a dryer and dry them at 50-60°C until the moisture content of the granules is less than 5%.

[0026] In another embodiment provided by the present invention, the granules are used to treat anemia caused by deficiency of both qi and blood, chronic blood loss, irregular menstruation, functional uterine bleeding, habitual abortion, postpartum evil leakage, chronic nephritis, chronic hepatitis, chronic bronchitis, chronic diarrhea, allergic purpura, arrhythmia, coronary heart disease, chronic heart failure, leukopenia, thrombocytopenic purpura, chronic osteomyelitis and other diseases, accompanied by dull headache, which occurs suddenly, stops suddenly, and worsens with overwork, and may be accompanied by palpitations and insomnia, pale complexion, fatigue, and the tongue coating is pale and thin white.

[0027] The dosage of granules is 5 to 10 grams for adults each time. The specific dosage can be adjusted according to the severity of symptoms, and it should be taken 2-3 times a day. For children or the elderly, it is recommended to reduce the dosage appropriately according to age and physical condition. It is generally recommended to take 3-5 grams each time, twice a day. It is recommended to take it half an hour after a meal to reduce irritation to the stomach and ensure the absorption of the drug. For the method of taking, take the granules with warm boiled water, stir well, and drink after ensuring that the granules are completely dissolved. It is generally taken for 7-10 consecutive days. If the symptoms are relieved, the dosage can be appropriately reduced.

[0028] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A Yin-nourishing and blood-nourishing headache granule for treating dull headache, characterized in that: The main Chinese medicinal ingredients of the granules include ginseng, atractylodes macrocephala, angelica sinensis, roasted licorice, cooked rehmannia, Poria cocos, peony and Chuanxiong, and the ratio of each ingredient by weight is: 5-10 parts of ginseng, 5-15 parts of atractylodes macrocephala, 10-20 parts of angelica sinensis, 3-8 parts of roasted licorice, 10-25 parts of cooked rehmannia, 5-15 parts of Poria cocos, 10-20 parts of peony and 10-20 parts of Chuanxiong.

2. The Yin-nourishing and blood-nourishing headache granules for treating headache according to claim 1, characterized in that: The Chinese herbal medicine composition may preferably include the following components: 8 parts of ginseng, 10 parts of atractylodes macrocephala, 15 parts of angelica sinensis, 5 parts of roasted liquorice, 18 parts of prepared rehmannia, 10 parts of tuckahoe, 15 parts of peony root, and 15 parts of ligusticum chuanxiong.

3. The Yin-nourishing and blood-nourishing headache granules for treating headache according to claim 1, characterized in that: The ginseng has the effects of invigorating qi and strengthening the spleen, replenishing the body's positive energy, improving immunity, helping to relieve fatigue and weakness caused by qi deficiency, calming the mind and soothing the nerves: regulating the central nervous system, helping to relieve headaches and dizziness, and improving sleep quality; The Atractylodes macrocephala invigorates the spleen and replenishes Qi, helps the spleen and stomach digest and absorb, improves symptoms of physical weakness caused by spleen deficiency, and promotes diuresis and eliminates dampness: it reduces moisture retention in the body, thereby relieving dizziness and headache; the Angelica sinensis invigorates blood and activates blood circulation, promotes blood circulation, improves symptoms of dizziness caused by blood deficiency, regulates menstruation and relieves pain, and relieves headaches caused by Qi stagnation and blood stasis, especially migraines.

4. The Yin-nourishing and blood-nourishing headache granules for treating dull headache according to claim 1, characterized in that: The roasted licorice harmonizes the various medicines, enhances the overall coordination of the formula, makes the medicinal properties of each medicinal material more harmonious, nourishes the spleen and replenishes qi, helps to strengthen the physical fitness, and improves headaches and fatigue caused by spleen deficiency; the cooked rehmannia nourishes yin and blood, replenishes the liver and kidney yin fluid, helps to improve headaches and dizziness caused by kidney deficiency, replenishes essence and marrow, helps to improve brain function, and enhances memory and concentration; the poria promotes diuresis and moisture absorption, promotes water metabolism in the body, helps to reduce the feeling of head swelling caused by moisture, strengthens the spleen and calms the mind, relieves anxiety, and improves symptoms of lack of energy and dizziness caused by spleen deficiency.

5. The Yin-nourishing and blood-nourishing headache granules for treating dull headache according to claim 1, characterized in that: The peony calms the liver and relieves pain, helps to soothe the liver and regulate qi, relieves headaches, and is particularly suitable for headaches caused by liver qi stagnation, softens the liver and nourishes blood, improves blood deficiency symptoms, and helps relieve dizziness caused by poor blood circulation; the Chuanxiong promotes blood circulation and qi, dredges the meridians, improves headaches and migraines caused by qi and blood stasis, dispels wind and relieves pain, and is used to relieve headaches caused by wind-cold, and improves the feeling of heaviness and swelling in the head.

6. The Yin-nourishing and blood-nourishing headache granules for treating headache according to claim 1, characterized in that: The particles are prepared by the following process steps: a. Weigh the following herbs by weight: 5-10 parts of ginseng, 5-15 parts of Atractylodes macrocephala, 10-20 parts of Angelica sinensis, 3-8 parts of licorice, 10-25 parts of Rehmannia glutinosa, 5-15 parts of Poria cocos, 10-20 parts of peony, 10-20 parts of Chuanxiong; b. Wash each raw medicinal material with clean water, remove impurities, and dry them for later use; c. Take each ingredient and grind them into fine powder according to their weight ratio; d. Mix all the fine powders evenly and add appropriate amount of water to form a moist mixture; e. Add appropriate amount of auxiliary materials, such as dextrin or starch, as needed to improve the formability of the particles and the stability of the drug, add appropriate amount of purified water, mix into a soft material mixture, stir until uniform, and control the humidity at 10%-15%; f. forming the soft material mixture into granules by a wet granulator; g. Place the prepared granules in a dryer and dry them at 50-60°C until the moisture content of the granules is less than 5%.

7. The Yin-nourishing and blood-nourishing headache granules for treating dull headache according to claim 1, characterized in that: The granules are used to treat anemia caused by deficiency of both qi and blood, chronic blood loss, irregular menstruation, functional uterine bleeding, habitual abortion, postpartum foul play, chronic nephritis, chronic hepatitis, chronic bronchitis, chronic diarrhea, allergic purpura, arrhythmia, coronary heart disease, chronic heart failure, leukopenia, thrombocytopenic purpura, chronic osteomyelitis and other diseases, accompanied by dull headache, which occurs suddenly, stops suddenly, and worsens with overwork, and may be accompanied by palpitations and insomnia, pale complexion, fatigue, and a pale tongue coating with a thin white coating.

8. The Yin-nourishing and blood-nourishing headache granules for treating dull headache according to claim 1, characterized in that: The dosage of the granules is 5 to 10 grams for adults each time. The specific dosage can be adjusted according to the severity of the symptoms, and it is taken 2-3 times a day. For children or the elderly, it is recommended to reduce the dosage appropriately according to age and physical condition. It is generally recommended to take 3-5 grams each time, twice a day. It is recommended to take it half an hour after a meal to reduce irritation to the stomach and ensure the absorption of the drug. For the method of taking, the granules are taken with warm boiled water, stirred thoroughly, and drunk after ensuring that the granules are completely dissolved. It is generally taken continuously for 7-10 days. If the symptoms are relieved, the dosage can be appropriately reduced.