Disinfection spray containing lonicerae flos extract and preparation method thereof

Abstract

The invention relates to the technical field of disinfectants, in particular to disinfection spray containing a lonicerae flos extract and a preparation method of the disinfection spray. Chlorogenic acid in the lonicerae flos extract and caffeic acid in the chia seed extract and the duchesnea indica extract have excellent antibacterial performance; the antibacterial agent is added into neutral electrolyte water as an antibacterial component to prepare disinfection spray, so that a powerful and lasting antibacterial effect can be provided, and the antibacterial agent has the advantages of safety and environment friendliness; the chlorogenic acid and the caffeic acid can effectively inhibit the growth of various bacteria, fungi and even some viruses, and the natural antibacterial components play an antibacterial role by destroying bacterial cell membranes, interfering the metabolic process or inhibiting DNA / RNA synthesis and the like, so that the disinfection spray can provide reliable disinfection effects in various environments, and moreover, the disinfection spray can be used as a disinfection spray for disinfection. Compared with a chemically synthesized antibacterial agent, natural antibacterial components such as chlorogenic acid and caffeic acid are safer and more environmentally friendly, and are friendly to human bodies and the environment.

Description

Technical Field

[0001] The invention relates to the technical field of disinfectants, and in particular to a disinfectant spray containing honeysuckle flower extract and a preparation method thereof. Background Art

[0002] With the growing demand for disinfection products in modern medical, health and healthcare fields, traditional disinfectants have been unable to meet the increasingly stringent safety and efficacy requirements due to their possible side effects and limited broad-spectrum bactericidal effects. Most of the disinfectants on the market are chemical disinfectants, but chemical reagents have a strong odor, can irritate the skin and respiratory tract, produce toxic byproducts that harm the environment, and produce a variety of drug-resistant bacteria, which are harmful to a certain extent.

[0003] In recent years, the use of single Chinese medicine or compound Chinese medicine as disinfectant has been increasing. Compared with single Chinese medicine, compound Chinese medicine has its unique advantages. On the one hand, it can better reflect the characteristics of traditional Chinese medicine theory of syndrome differentiation and treatment, and better reflect the holistic view of Chinese medicine; on the other hand, single Chinese medicine has a relatively single or few targets, which is easy to cause drug resistance, while compound Chinese medicine has the advantage of multiple targets, which can better play an antibacterial and bactericidal effect and prevent the occurrence of drug-resistant bacteria. Therefore, how to design a disinfectant spray with compound Chinese medicine as raw material, while maintaining excellent bactericidal performance, can also reduce its toxic side effects, has become a technical problem that needs to be solved urgently by technicians in this field. Summary of the invention

[0004] Technical issues solved

[0005] In view of the above-mentioned shortcomings of the prior art, the present invention provides a disinfectant spray containing honeysuckle extract and a preparation method thereof, aiming to enable the prepared disinfectant spray to reduce its toxic side effects while maintaining excellent bactericidal performance.

[0006] Technical Solution

[0007] To achieve the above objectives, the present invention is implemented through the following technical solutions:

[0008] A disinfectant spray containing honeysuckle extract, the disinfectant spray containing honeysuckle extract consisting of the following components:

[0009] Honeysuckle flower extract, chia seed extract, snakeberry extract, complex plant extract, neutral electrolyte water, sophoracarpine, berberine, surfactant component and deionized water;

[0010] The composite plant extract is prepared by extracting atractylodes, wormwood leaves, dalbergia odorifera, atractylodes macrocephala, angelica dahurica and calamus.

[0011] Furthermore, the preparation method of the honeysuckle extract is:

[0012] S2.1. Wash the honeysuckle buds and dry them in a 60°C forced air drying oven for 24 hours. Grind them and pass them through an 80-mesh sieve. The obtained powder is recorded as honeysuckle powder.

[0013] S2.2. Weigh 2-3g of honeysuckle powder and disperse it in a 70% ethanol aqueous solution. Adjust the pH value to 4 and extract it in a 100°C water bath under reflux conditions for 2 hours. Filter the obtained extract through a Buchner funnel and centrifuge it at 5000r / min for 5 minutes. The obtained supernatant is the honeysuckle extract.

[0014] Furthermore, in S2.2, a sulfuric acid solution with a concentration of 1 mol / L or a sodium hydroxide solution with a mass fraction of 10% is used to adjust the pH value.

[0015] Furthermore, the preparation method of the chia seed extract is:

[0016] After cleaning the chia seeds, dry them in a 62°C forced air drying oven for 24 hours. Grind them through a 60-mesh sieve, weigh 2-3 g, and disperse them in 20 mL of 80% ethanol aqueous solution. Ultrasonic disperse them at a power of 250 W for 30 minutes, and centrifuge them at a speed of 6000 r / min for 5 minutes. The resulting supernatant is the chia seed extract.

[0017] Furthermore, the preparation method of the snakeberry extract is:

[0018] After crushing the snakeberry through a 50-mesh sieve, take 5 g and disperse it in 100 g deionized water, then extract it in a 100°C water bath under reflux conditions for 3 hours. The obtained extract is concentrated by rotary evaporation at 65°C to 1 / 2 of the original volume, then 50 mL of anhydrous ethanol is added and the supernatant obtained after standing for 24 hours is the snakeberry extract.

[0019] Furthermore, the preparation method of the composite plant extract is:

[0020] Atractylodes lancea, Artemisia argyi, Dalbergia odorifera, Atractylodes macrocephala, Angelica dahurica and Acorus calamus are mixed in equal weight ratios and ground through a 60-mesh sieve. Then 5-8 g are weighed and dispersed in 100 mL of deionized water. After soaking for 3-4 hours, the mixture is placed in a volatile oil extractor and heated to reflux at 105° C. The resulting volatile oil is the composite plant extract.

[0021] Furthermore, the preparation method of the neutral electrolyte water is:

[0022] Weigh 5 g of salt and dissolve it in 500 mL of deionized water. After stirring at a speed of 500 r / min for 10 min, place it in an oxidizing potential water generator and start it for 9 min. The result is neutral electrolyte water.

[0023] Furthermore, the surfactant component is prepared by mixing polyoxyethylene hydrogenated castor oil, polysorbate-80 and caprylic / capric macrogol glyceride in equal weight ratios.

[0024] A method for preparing a disinfectant spray containing honeysuckle extract, the preparation method comprising:

[0025] S1, weighing 25-30 parts by weight of honeysuckle flower extract, 18-22 parts by weight of chia seed extract, 20-24 parts by weight of snakeberry extract and 25-28 parts by weight of composite plant extract, mixing them, stirring and mixing them evenly, placing them at 65° C. and concentrating them by rotary evaporation to 1 / 3 of the original volume, and the obtained volume is recorded as the extract component;

[0026] S2. Pour the extract component and 1-2 parts by weight of the surfactant component into 60-80 parts by weight of neutral electrolyte water, add 12-14 parts by weight of sophorafruit, 8-10 parts by weight of berberine and 20-30 parts by weight of deionized water under stirring conditions, and obtain a disinfectant spray containing honeysuckle extract after ultrasonic dispersion.

[0027] Furthermore, the specific operation of stirring and mixing uniformly in S1 is stirring at a speed of 500 r / min for 10 min, the speed of the stirring condition in S2 is 300 r / min, and the specific operation of ultrasonic dispersion in S2 is ultrasonic dispersion at a frequency of 30 kHz for 20 min.

[0028] Beneficial Effects

[0029] The present invention provides a disinfectant spray containing honeysuckle extract and a preparation method thereof. Compared with the prior art, the present invention has the following beneficial effects:

[0030] The chlorogenic acid in the honeysuckle extract and the caffeic acid in the chia seed extract and the snakeberry extract of the present invention all have excellent antibacterial properties. Adding them as antibacterial ingredients to neutral electrolyte water to prepare a disinfectant spray can not only provide a strong and lasting antibacterial effect, but also have the advantages of safety and environmental protection; chlorogenic acid and caffeic acid can effectively inhibit the growth of a variety of bacteria, fungi and even certain viruses. These natural antibacterial ingredients exert their antibacterial effects by destroying bacterial cell membranes, interfering with their metabolic processes or inhibiting their DNA / RNA synthesis, so that the disinfectant spray can provide reliable disinfection effects in a variety of environments. Moreover, compared with chemically synthesized antibacterial agents, natural antibacterial ingredients such as chlorogenic acid and caffeic acid are safer, more environmentally friendly, and friendly to the human body and the environment.

[0031] Secondly, in addition to chlorogenic acid, honeysuckle extract is also rich in other ingredients that are beneficial to the skin, such as flavonoids. These ingredients have certain moisturizing and antioxidant effects. Adding honeysuckle extract to disinfectant spray can not only enhance the disinfection effect, but also protect the skin from irritation while disinfecting. It is suitable for skin surface disinfection and can have certain skin care effects.

[0032] Finally, the present invention further adds a composite plant extract to the disinfectant spray. The composite plant extract is volatile oil extracted from atractylodes, wormwood, dalbergia odorifera, atractylodes macrocephala, angelica dahurica and calamus tatarinowii, which has obvious in vitro antibacterial effect on Staphylococcus aureus and the like. It is added to the disinfectant spray together with sophoracarpine and berberine to further stabilize the antibacterial performance of the disinfectant spray; secondly, the atractylodes macrocephala in the composite plant extract can regulate the oil secretion of the skin, and for oily skin, it helps to reduce excessive oil secretion and keep the skin fresh. The wormwood has a soothing effect and can reduce skin inflammation and redness. The dalbergia odorifera can promote the regeneration of skin cells, help repair damaged skin, and make the skin smoother and more delicate. The angelica dahurica can accelerate skin metabolism. The atractylodes macrocephala and calamus tatarinowii have a moisturizing effect and can lock skin moisture to prevent dryness and roughness of the skin. Therefore, the addition of the composite plant extract can play a better skin care effect. DETAILED DESCRIPTION

[0033] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] The present invention will be further described below in conjunction with the embodiments.

[0035] Example 1

[0036] The disinfectant spray containing honeysuckle extract of this embodiment is composed of the following components: honeysuckle extract, chia seed extract, snakeberry extract, composite plant extract, neutral electrolyte water, sophoracarpine, berberine, surfactant component and deionized water.

[0037] Wherein, the preparation method of honeysuckle extract is:

[0038] S2.1. Wash the honeysuckle buds and dry them in a 60°C forced air drying oven for 24 hours. Grind them and pass them through an 80-mesh sieve. The obtained powder is recorded as honeysuckle powder.

[0039] S2.2. Weigh 2 g of honeysuckle powder and disperse it in a 70% ethanol aqueous solution. Use a 1 mol / L sulfuric acid solution to adjust the pH value to 4, and then extract it in a 100°C water bath under reflux conditions for 2 hours. The obtained extract is filtered through a Buchner funnel and centrifuged at 5000 r / min for 5 minutes. The obtained supernatant is the honeysuckle extract.

[0040] The preparation method of chia seed extract is as follows:

[0041] After cleaning the chia seeds, dry them in a 62°C forced air drying oven for 24 hours. Grind them through a 60-mesh sieve, weigh 2 g, and disperse them in 20 mL of 80% ethanol aqueous solution. Ultrasonic dispersion was performed at a power of 250 W for 30 minutes, and then centrifuged at a speed of 6000 r / min for 5 minutes. The supernatant obtained was the chia seed extract.

[0042] The preparation method of snakeberry extract is as follows:

[0043] After crushing the snakeberry through a 50-mesh sieve, take 5 g and disperse it in 100 g deionized water, then extract it in a 100°C water bath under reflux conditions for 3 hours. The obtained extract is concentrated by rotary evaporation at 65°C to 1 / 2 of the original volume, then 50 mL of anhydrous ethanol is added and the supernatant obtained after standing for 24 hours is the snakeberry extract.

[0044] The composite plant extract is prepared by extracting Atractylodes lancea, Artemisia argyi, Dalbergia odorifera, Atractylodes macrocephala, Angelica dahurica and Acorus calamus. The preparation method of the composite plant extract is as follows:

[0045] Atractylodes lancea, Artemisia argyi, Dalbergia odorifera, Atractylodes macrocephala, Angelica dahurica and Acorus calamus are mixed in equal weight ratios and ground through a 60-mesh sieve. Then 5 g is weighed and dispersed in 100 mL of deionized water. After soaking for 3 hours, the mixture is placed in a volatile oil extractor and heated to reflux at 105° C. The resulting volatile oil is the composite plant extract.

[0046] The preparation method of neutral electrolyte water is:

[0047] Weigh 5 g of salt and dissolve it in 500 mL of deionized water. After stirring at a speed of 500 r / min for 10 min, place it in an oxidizing potential water generator and start it for 9 min. The result is neutral electrolyte water.

[0048] The surfactant component is prepared by mixing polyoxyethylene hydrogenated castor oil, polysorbate-80 and caprylic acid capric acid macrogol glyceride in equal weight ratio.

[0049] A method for preparing a disinfectant spray containing honeysuckle extract, the preparation method comprising:

[0050] S1, weighing 25 parts by weight of honeysuckle flower extract, 18 parts by weight of chia seed extract, 20 parts by weight of snakeberry extract and 25 parts by weight of composite plant extract, mixing them, stirring at a speed of 500 r / min for 10 min, and then placing them at a temperature of 65° C. and concentrating them by rotary evaporation to 1 / 3 of the original volume, and the obtained volume is recorded as the extract component;

[0051] S2. Pour the extract component and 1 part by weight of the surfactant component into 60 parts by weight of neutral electrolyte water, add 12 parts by weight of sophorafruit, 8 parts by weight of berberine and 20 parts by weight of deionized water under stirring at a speed of 300 r / min, and ultrasonically disperse at a frequency of 30 kHz for 20 minutes to obtain a disinfectant spray containing the honeysuckle extract.

[0052] Example 2

[0053] The disinfectant spray containing honeysuckle extract of this embodiment is composed of the following components: honeysuckle extract, chia seed extract, snakeberry extract, composite plant extract, neutral electrolyte water, sophoracarpine, berberine, surfactant component and deionized water.

[0054] Wherein, the preparation method of honeysuckle extract is:

[0055] S2.1. Wash the honeysuckle buds and dry them in a 60°C forced air drying oven for 24 hours. Grind them and pass them through an 80-mesh sieve. The obtained powder is recorded as honeysuckle powder.

[0056] S2.2. Weigh 3 g of honeysuckle powder and disperse it in a 70% ethanol aqueous solution. Use a 1 mol / L sulfuric acid solution to adjust the pH value to 4, and then extract it in a 100°C water bath under reflux conditions for 2 hours. The obtained extract is filtered through a Buchner funnel and centrifuged at 5000 r / min for 5 minutes. The obtained supernatant is the honeysuckle extract.

[0057] The preparation method of chia seed extract is as follows:

[0058] After cleaning the chia seeds, dry them in a 62°C forced air drying oven for 24 hours. Grind them through a 60-mesh sieve, weigh 3 g, and disperse them in 20 mL of 80% ethanol aqueous solution. Ultrasonic dispersion was performed at a power of 250 W for 30 minutes, and then centrifuged at a speed of 6000 r / min for 5 minutes. The supernatant obtained was the chia seed extract.

[0059] The preparation method of snakeberry extract is as follows:

[0060] After crushing the snakeberry through a 50-mesh sieve, take 5 g and disperse it in 100 g deionized water, then extract it in a 100°C water bath under reflux conditions for 3 hours. The obtained extract is concentrated by rotary evaporation at 65°C to 1 / 2 of the original volume, then 50 mL of anhydrous ethanol is added and the supernatant obtained after standing for 24 hours is the snakeberry extract.

[0061] The composite plant extract is prepared by extracting Atractylodes lancea, Artemisia argyi, Dalbergia odorifera, Atractylodes macrocephala, Angelica dahurica and Acorus calamus. The preparation method of the composite plant extract is as follows:

[0062] Atractylodes lancea, Artemisia argyi, Dalbergia odorifera, Atractylodes macrocephala, Angelica dahurica and Acorus calamus are mixed in equal weight ratios and ground through a 60-mesh sieve. Then 8 g is weighed and dispersed in 100 mL of deionized water. After soaking for 4 hours, the mixture is placed in a volatile oil extractor and heated to reflux at 105° C. The resulting volatile oil is the composite plant extract.

[0063] The preparation method of neutral electrolyte water is:

[0064] Weigh 5 g of salt and dissolve it in 500 mL of deionized water. After stirring at a speed of 500 r / min for 10 min, place it in an oxidizing potential water generator and start it for 9 min. The result is neutral electrolyte water.

[0065] The surfactant component is prepared by mixing polyoxyethylene hydrogenated castor oil, polysorbate-80 and caprylic acid capric acid macrogol glyceride in equal weight ratio.

[0066] A method for preparing a disinfectant spray containing honeysuckle extract, the preparation method comprising:

[0067] S1, weighing 30 parts by weight of honeysuckle flower extract, 22 parts by weight of chia seed extract, 24 parts by weight of snakeberry extract and 28 parts by weight of composite plant extract, mixing them, stirring at a speed of 500 r / min for 10 min, and then placing them at a temperature of 65° C. and concentrating them by rotary evaporation to 1 / 3 of the original volume, and the obtained mixture was recorded as the extract component;

[0068] S2. Pour the extract component and 2 parts by weight of the surfactant component into 80 parts by weight of neutral electrolyte water, add 14 parts by weight of sophorafruit, 10 parts by weight of berberine and 30 parts by weight of deionized water under stirring at a speed of 300 r / min, and ultrasonically disperse at a frequency of 30 kHz for 20 minutes to obtain a disinfectant spray containing the honeysuckle extract.

[0069] Example 3

[0070] The disinfectant spray containing honeysuckle extract of this embodiment is composed of the following components: honeysuckle extract, chia seed extract, snakeberry extract, composite plant extract, neutral electrolyte water, sophoracarpine, berberine, surfactant component and deionized water.

[0071] Wherein, the preparation method of honeysuckle extract is:

[0072] S2.1. Wash the honeysuckle buds and dry them in a 60°C forced air drying oven for 24 hours. Grind them and pass them through an 80-mesh sieve. The obtained powder is recorded as honeysuckle powder.

[0073] S2.2. Weigh 3 g of honeysuckle powder and disperse it in a 70% ethanol aqueous solution. Use a 1 mol / L sulfuric acid solution to adjust the pH value to 4, and then extract it in a 100°C water bath under reflux conditions for 2 hours. The obtained extract is filtered through a Buchner funnel and centrifuged at 5000 r / min for 5 minutes. The obtained supernatant is the honeysuckle extract.

[0074] The preparation method of chia seed extract is as follows:

[0075] After cleaning the chia seeds, dry them in a 62°C forced air drying oven for 24 hours. Grind them through a 60-mesh sieve, weigh 2 g, and disperse them in 20 mL of 80% ethanol aqueous solution. Ultrasonic dispersion was performed at a power of 250 W for 30 minutes, and then centrifuged at a speed of 6000 r / min for 5 minutes. The supernatant obtained was the chia seed extract.

[0076] The preparation method of snakeberry extract is as follows:

[0077] After crushing the snakeberry through a 50-mesh sieve, take 5 g and disperse it in 100 g deionized water, then extract it in a 100°C water bath under reflux conditions for 3 hours. The obtained extract is concentrated by rotary evaporation at 65°C to 1 / 2 of the original volume, then 50 mL of anhydrous ethanol is added and the supernatant obtained after standing for 24 hours is the snakeberry extract.

[0078] The composite plant extract is prepared by extracting Atractylodes lancea, Artemisia argyi, Dalbergia odorifera, Atractylodes macrocephala, Angelica dahurica and Acorus calamus. The preparation method of the composite plant extract is as follows:

[0079] Atractylodes lancea, Artemisia argyi, Dalbergia odorifera, Atractylodes macrocephala, Angelica dahurica and Acorus calamus are mixed in equal weight ratios and ground through a 60-mesh sieve. Then 5 g is weighed and dispersed in 100 mL of deionized water. After soaking for 3 hours, the mixture is placed in a volatile oil extractor and heated to reflux at 105° C. The resulting volatile oil is the composite plant extract.

[0080] The preparation method of neutral electrolyte water is:

[0081] Weigh 5 g of salt and dissolve it in 500 mL of deionized water. After stirring at a speed of 500 r / min for 10 min, place it in an oxidizing potential water generator and start it for 9 min. The result is neutral electrolyte water.

[0082] The surfactant component is prepared by mixing polyoxyethylene hydrogenated castor oil, polysorbate-80 and caprylic acid capric acid macrogol glyceride in equal weight ratio.

[0083] A method for preparing a disinfectant spray containing honeysuckle extract, the preparation method comprising:

[0084] S1, weighing 28 parts by weight of honeysuckle flower extract, 20 parts by weight of chia seed extract, 22 parts of snakeberry extract and 27 parts by weight of composite plant extract, mixing them, stirring at a speed of 500 r / min for 10 min, and then placing them at a temperature of 65° C. and concentrating them by rotary evaporation to 1 / 3 of the original volume, and the obtained volume is recorded as the extract component;

[0085] S2. Pour the extract component and 2 parts by weight of the surfactant component into 70 parts by weight of neutral electrolyte water, add 13 parts by weight of sophorafruit, 9 parts by weight of berberine and 25 parts by weight of deionized water under stirring at a speed of 300 r / min, and ultrasonically disperse at a frequency of 30 kHz for 20 minutes to obtain a disinfectant spray containing honeysuckle extract.

[0086] Comparative Example 1

[0087] The disinfectant spray containing honeysuckle extract and the preparation method thereof provided in this comparative example are substantially the same as those in Example 1, with the main difference being that in this comparative example 1, the honeysuckle extract in Example 1 is replaced with deionized water.

[0088] Comparative Example 2

[0089] The disinfectant spray containing honeysuckle extract and the preparation method thereof provided in this comparative example are substantially the same as those in Example 1, with the main difference being that the chia seed extract in Example 1 is replaced with deionized water in this comparative example 2.

[0090] Comparative Example 3

[0091] The disinfectant spray containing honeysuckle extract and the preparation method thereof provided in this comparative example are substantially the same as those in Example 1, with the main difference being that in this comparative example 3, the snakeberry extract in Example 1 is replaced with deionized water.

[0092] Performance Testing

[0093] The antibacterial performance of the disinfectant spray containing honeysuckle extract in Examples 1-3 and Comparative Examples 1-3 was tested, and the test strains were Staphylococcus aureus, Escherichia coli, and Candida albicans; the neutralizer was a PBS solution containing 0.5% sodium thiosulfate, 3% Tween-80, and 1% soy lecithin; the disinfectant was the disinfectant spray containing honeysuckle extract in Examples 1-3 and Comparative Examples 1-3. The neutralizer identification test and the quantitative bactericidal test were carried out in accordance with Articles 5.2.1.4 and 5.2.1.5 of the "Antibacterial and Antibacterial Effect Evaluation Method" (WS / T 650-2019) issued by the National Health Commission of the People's Republic of China, respectively. If the bactericidal rate is ≥90% at the specified time, it is judged to have an antibacterial effect; if the bactericidal rate is ≥99% at the time specified in the instructions, it is judged to have a strong antibacterial effect. The obtained data are recorded in the following table:

[0094]

[0095] Among them, the concentration of Staphylococcus aureus in the experimental group was 4.55×10 4 The bacterial concentration in the positive control group was 1.40×10 8 ; The concentration of E. coli in the experimental group was 7.85×10 4 The bacterial concentration in the positive control group was 1.18×10 8 ; The bacterial concentration of Candida albicans in the experimental group was 7.50×10 3 The bacterial concentration in the positive control group was 3.80×10 7 .

[0096] It can be seen from the data in the above table that the sterilization rate of the disinfectant spray containing honeysuckle extract in Examples 1-3 is significantly higher than that in Comparative Examples 1-3, indicating that the disinfectant spray prepared by mixing honeysuckle extract, chia seed extract and snakeberry extract has better antibacterial performance.

[0097] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the presence of other identical elements in the process, method, article or device including the elements.

[0098] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments may still be modified, or some of the technical features may be replaced by equivalents. Such modifications or replacements will not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A disinfectant spray containing honeysuckle extract, characterized in that: The disinfectant spray containing honeysuckle extract is composed of the following components: Honeysuckle flower extract, chia seed extract, snakeberry extract, complex plant extract, neutral electrolyte water, sophoracarpine, berberine, surfactant component and deionized water; The composite plant extract is prepared by extracting atractylodes, wormwood leaves, dalbergia odorifera, atractylodes macrocephala, angelica dahurica and calamus.

2. The disinfectant spray containing honeysuckle extract according to claim 1, characterized in that: The preparation method of the honeysuckle extract is as follows: S2.

1. Wash the honeysuckle buds and dry them in a 60°C forced air drying oven for 24 hours. Grind them and pass them through an 80-mesh sieve. The obtained powder is recorded as honeysuckle powder. S2.

2. Weigh 2-3g of honeysuckle powder and disperse it in a 70% ethanol aqueous solution. Adjust the pH value to 4 and extract it in a 100°C water bath under reflux conditions for 2 hours. Filter the obtained extract through a Buchner funnel and centrifuge it at 5000r / min for 5 minutes. The obtained supernatant is the honeysuckle extract.

3. The disinfectant spray containing honeysuckle extract according to claim 2, characterized in that: In S2.2, a sulfuric acid solution with a concentration of 1 mol / L or a sodium hydroxide solution with a mass fraction of 10% is used to adjust the pH value.

4. The disinfectant spray containing honeysuckle extract according to claim 1, characterized in that: The preparation method of the chia seed extract is: After cleaning the chia seeds, dry them in a 62°C forced air drying oven for 24 hours. Grind them through a 60-mesh sieve, weigh 2-3 g, and disperse them in 20 mL of 80% ethanol aqueous solution. Ultrasonic disperse them at a power of 250 W for 30 minutes, and centrifuge them at a speed of 6000 r / min for 5 minutes. The resulting supernatant is the chia seed extract.

5. The disinfectant spray containing honeysuckle extract according to claim 1, characterized in that: The preparation method of the snakeberry extract is: After crushing the snakeberry through a 50-mesh sieve, take 5 g and disperse it in 100 g deionized water, then extract it in a 100°C water bath under reflux conditions for 3 hours. The obtained extract is concentrated by rotary evaporation at 65°C to 1 / 2 of the original volume, then 50 mL of anhydrous ethanol is added and the supernatant obtained after standing for 24 hours is the snakeberry extract.

6. The disinfectant spray containing honeysuckle extract according to claim 1, characterized in that: The preparation method of the composite plant extract is as follows: Atractylodes lancea, Artemisia argyi, Dalbergia odorifera, Atractylodes macrocephala, Angelica dahurica and Acorus calamus are mixed in equal weight ratios and ground through a 60-mesh sieve. Then 5-8 g are weighed and dispersed in 100 mL of deionized water. After soaking for 3-4 hours, the mixture is placed in a volatile oil extractor and heated to reflux at 105° C. The resulting volatile oil is the composite plant extract.

7. The disinfectant spray containing honeysuckle extract according to claim 1, characterized in that: The preparation method of the neutral electrolyte water is: Weigh 5 g of salt and dissolve it in 500 mL of deionized water. After stirring at a speed of 500 r / min for 10 min, place it in an oxidizing potential water generator and start it for 9 min. The result is neutral electrolyte water.

8. The disinfectant spray containing honeysuckle extract according to claim 1, characterized in that: The surfactant component is prepared by mixing polyoxyethylene hydrogenated castor oil, polysorbate-80 and caprylic acid capric acid macrogol glyceride in equal weight ratio.

9. The method for preparing a disinfectant spray containing honeysuckle extract according to any one of claims 1 to 8, characterized in that: The preparation method is: S1, weighing 25-30 parts by weight of honeysuckle flower extract, 18-22 parts by weight of chia seed extract, 20-24 parts by weight of snakeberry extract and 25-28 parts by weight of composite plant extract, mixing them, stirring and mixing them evenly, placing them at 65° C. and concentrating them by rotary evaporation to 1 / 3 of the original volume, and the obtained volume is recorded as the extract component; S2. Pour the extract component and 1-2 parts by weight of the surfactant component into 60-80 parts by weight of neutral electrolyte water, add 12-14 parts by weight of sophorafruit, 8-10 parts by weight of berberine and 20-30 parts by weight of deionized water under stirring conditions, and obtain a disinfectant spray containing honeysuckle extract after ultrasonic dispersion.

10. The method for preparing a disinfectant spray containing honeysuckle extract according to claim 9, characterized in that: The specific operation of stirring and mixing uniformly in S1 is stirring at a speed of 500 r / min for 10 min, the stirring speed in S2 is 300 r / min, and the specific operation of ultrasonic dispersion in S2 is ultrasonic dispersion at a frequency of 30 kHz for 20 min.

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